[H]C1=C([H])C([H])=C2C(=C1[H])C([H])([H])C([H])([H])[C@]2([H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])C(C([H])([H])[H])(C([H])([H])[H])C1([H])[H]
[H]O[C@]1([H])C([H])([H])C([H])([H])[C@]2([H])[C@]3([H])C([H])([H])C([H])([H])C4=C(C([H])=C(OC([H])([H])[H])C(OS(=O)(=O)N([H])[H])=C4[H])[C@@]3([H])C([H])([H])C([H])([H])[C@]12C([H])([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1F)C([H])([H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C([H])C([H])=C(OC([H])([H])[H])C([H])=C2OC([H])([H])[H])C([H])([H])C1([H])[H]
[H]N1C([H])=C(C2=C1C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])=C(C2=C(F)C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
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COC1=CC=C2C=C(CNCCC3=CC(Br)=CC=C3)C(=NC2=C1)C1=CSC=C1
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[H]OC1=C([H])C([H])=C(N([H])C(=O)C2=NC([H])=NC(N([H])C3=C([H])C([H])=C([H])C([H])=C3C([H])([H])[H])=C2[H])C([H])=C1[H]
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[H]N(C(=O)N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C([H])C(\C([H])=C(/[H])C2=NN([H])C3=C([H])C(N4C([H])([H])C([H])([H])C([H])([H])C4([H])[H])=C(N([H])S(=O)(=O)C([H])([H])[H])C([H])=C23)=C1[H]
[H]N([H])S(=O)(=O)C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C2=C(C([H])=NC([H])=C2[H])C([H])=C1OC([H])([H])C1([H])C([H])([H])C([H])([H])N([H])C([H])([H])C1([H])[H]
[H]N([H])C1=NC2=C(C([H])=NN2C([H])([H])C([H])([H])C([H])([H])C2=C([H])C([H])=C(OC([H])([H])[H])C(OC([H])([H])[H])=C2[H])C2=NC(=NN12)C1=C([H])C([H])=C([H])O1
[H]N([H])C(=N\C1=C(C([H])=C([H])C([H])=C1[H])C([H])([H])[H])\N([H])C1=C(N([H])[H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)C([H])([H])N(C(=O)C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=N1)C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C1=C([H])C(F)=C([H])C(F)=C1[H]
[H]N(C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1N1C([H])([H])C([H])([H])N(C(=O)[C@]2([H])C([H])([H])N(C([H])([H])[C@@]2([H])C2=C([H])C([H])=C(Cl)C([H])=C2[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H])S(=O)(=O)C([H])([H])[H]
[H]N([H])C1=C([H])C(Cl)=C([H])C([H])=C1SC1=C([H])C([H])=C([H])C([H])=C1C([H])([H])N(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)C1=C(C(=NC2=C([H])C([H])=C([H])C([H])=C12)C1=C([H])C([H])=C([H])C(F)=C1[H])C([H])([H])N(C([H])([H])[H])S(=O)(=O)C([H])([H])[H])[C@]([H])(C1=C([H])C(F)=C([H])C([H])=C1[H])C1([H])C([H])([H])C1([H])[H]
[H]OC(=O)C(=C([H])[H])C([H])([H])[C@@]([H])(N([H])C(=O)C1=C([H])C([H])=C(N([H])C([H])([H])C2=NC3=C(N=C(N=C3N=C2[H])N([H])[H])N([H])[H])C([H])=C1[H])C(=O)O[H]
[H]O[C@]([H])(C1=C([H])C([H])=C([H])N=C1[H])C([H])([H])N([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C(N([H])C(=O)C2=NC3=C(N2[H])C([H])=C([H])C([H])=C3[H])C([H])=C1[H]
[H]C#CC1=C([H])C([H])=C([H])C(=C1[H])[C@@]1([H])C2=C([H])C([H])=C(OC([H])([H])C([H])([H])C([H])([H])N3C([H])([H])C([H])([H])C([H])([H])C([H])([H])C3([H])[H])C([H])=C2[C@@]2([H])N(C([H])([H])C([H])([H])C2([H])[H])C1([H])[H]
[H]N(C(=O)[C@]([H])(N([H])C(=O)C1(N([H])C(=O)C2=C([H])C([H])=C(C([H])=C2[H])C2=C([H])C([H])=C(C([H])=C2[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C2([H])C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C(=O)C([H])=C([H])C1=O
[H]N(C(=O)C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])N([H])N=C1C1=NC2=C([H])C([H])=C([H])C([H])=C2N1[H]
[H]C1=C(N(C2=C1C([H])=NC(=N2)C#N)C([H])([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C(=O)N(C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])C([H])=C(N2N=C3C(OC([H])([H])C([H])([H])C([H])([H])[C@@]3([H])N3C(=O)C([H])([H])C([H])([H])C3([H])[H])=C2C2=C([H])C([H])=C(Cl)C([H])=C2[H])C(Cl)=C1[H]
[H]OC1=NC(=NC2=C1C([H])=C(C([H])=C2[H])C([H])([H])N(C1=C([H])C([H])=C(C([H])=C1[H])C(=O)N([H])C([H])([H])C1=C([H])C([H])=C([H])C(=C1[H])[N+]([O-])=O)C([H])([H])C#C[H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H]
[H]OC(=O)C([H])([H])C([H])([H])C1=C([H])C([H])=C(OC([H])([H])C([H])([H])N(C2=NC3=C([H])C([H])=C([H])C([H])=C3S2)C([H])([H])C2=C([H])C([H])=C(C([H])=C2[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])=C1[H]
[H]OC1=C([H])C([H])=C([H])C([H])=C1C(=O)N([H])\N=C1/OC2=C([H])C([H])=C([H])C([H])=C2C([H])=C1C(=O)N([H])[H]
[H]N(C(=O)C1=C(N(C(=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C([H])C(Cl)=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]OC1=C([H])C([H])=C([H])C(=C1[H])C1=C([H])N(C2=NC([H])=NC(N([H])[H])=C12)C1([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]OC([H])([H])C1=C([H])C([H])=C([H])C([H])=C1N1C([H])=C(C2=C(N=C([H])N=C12)N([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
CCNC(=O)NC1=CC=C(C=C1)C1=NC2=C(CCN(C2)C2=NC=C(F)C=N2)C(=N1)N1CCOC[C@@H]1C
[H]O[C@@]1([H])C([H])([H])C(=O)O[C@@]([H])(C([H])([H])C([H])([H])C2=C(Cl)C([H])=C(Cl)C3=C([H])C(Cl)=C([H])C([H])=C23)C1([H])[H]
[H]C1=C([H])C([H])=C(OC2([H])C([H])([H])C([H])([H])N(C3=NN=C(C([H])=C3[H])C3=NOC(=N3)C([H])([H])[H])C([H])([H])C2([H])[H])C(Cl)=C1[H]
[H]OC([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])[C@@]1([H])C2=C(C([H])=C(Cl)C([H])=C2[H])[C@@]([H])(C2=C([H])C([H])=C(F)C([H])=C2[H])C1([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C(=O)N(C([H])([H])[H])C([H])([H])C([H])([H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C(C([H])=C2[H])[N+]([O-])=O)C([H])([H])C1([H])[H]
[H]N(C(=O)C([H])([H])C1=C([H])C([H])=NC([H])=C1[H])C1=NC([H])=C(\C([H])=C(/[H])C(=O)N([H])C([H])([H])C(=O)N(C2=C(Cl)C(=C(Cl)C([H])=C2[H])C([H])([H])OC2=C3N=C(C([H])=C(OC([H])([H])C4=C([H])C([H])=C([H])C([H])=N4)C3=C([H])C([H])=C2[H])C([H])([H])[H])C([H])([H])[H])C([H])=C1[H]
[H]N([H])[C@@]([H])(C([H])([H])[H])C([H])([H])C1=C([H])C(OC([H])([H])[H])=C(C([H])=C1OC([H])([H])[H])C([H])([H])C([H])([H])[H]
[H]N([H])C(=[N+]([H])[H])C1=C([H])C([H])=C([H])C(=C1[H])N1C(=O)N(C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])S(=O)(=O)C([H])([H])C1=NC([H])=C([H])C([H])=C1[H]
[H]N1C(=O)N(C([H])([H])C1(C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C([H])C(OC([H])([H])[H])=C2[H])C([H])([H])C1([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C([H])C([H])=C1[H])C1=NC([H])=C([H])C(=C1[H])C1=NN([H])C(=O)N1C1=C([H])C2=C([H])C([H])=C([H])C([H])=C2C([H])=C1[H]
[H]N([H])C([H])([H])C([H])([H])C(=O)N([H])[C@@]([H])(C(=O)N1C([H])([H])C([H])([H])N(C2=NC([H])=C([H])C([H])=C2C([H])([H])N([H])C(=O)OC2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C(Cl)C([H])=C1Cl
[H]N1C(=NC([H])([H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C(C(OC([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])=C1C([H])([H])[H])C([H])([H])[H]
[H]N([H])[C@@]1([H])C([H])([H])N(C2=NC3=C(N2C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2Cl)C(=O)N(C2=C3C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C1([H])[H]
[H]C1=C([H])C(OC([H])([H])[H])=C([H])C(=C1[H])C(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C([H])C([H])=C(Cl)C([H])=C2[H])C([H])([H])C1([H])[H]
[H]OC(=O)C([H])([H])[C@]([H])(C(=O)N([H])[C@@]([H])(C(=O)N([H])C([H])([H])[H])C([H])([H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N1\C(S\C(=C(\[H])C2=C(N(N=C2[H])C2=C([H])C([H])=C(F)C([H])=C2[H])C([H])([H])[H])C1=O)=N\C([H])([H])[H]
[H]N(C1=C2C([H])=C([H])C(F)=C([H])C2=C2C(=O)N([H])C([H])=C([H])C2=N1)C1([H])C([H])([H])C(F)(F)C1([H])[H]
[H]N([H])C1=N[C@](C(=O)N1C([H])([H])[H])(C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])[C@]12C([H])([H])[C@@]3([H])C([H])([H])[C@]([H])(C([H])([H])[C@]([H])(C3([H])[H])C1([H])[H])C2([H])[H]
[H]N(C(=O)C([H])([H])OC1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C2=C(N1[H])C(=O)N(C(=O)N2C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]OC1=C([H])C([H])=C([H])C([H])=C1C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])OC([H])(C2=C([H])C([H])=C(F)C([H])=C2[H])C2=C([H])C([H])=C(F)C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N1N(C(SC([H])([H])C2=C(N3C(=O)[C@]([H])(OC([H])([H])[H])[C@@]3([H])S(=O)(=O)C2([H])[H])C(=O)OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])=NC(=O)C1=O)C([H])([H])[H]
[H]SC1=NN=C(S1)N([H])C(=O)N([H])[C@]([H])(C(=O)N1C([H])([H])C([H])([H])N(C2=NC([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N1C(=O)\C(=C(/[H])C(=O)C2=C([H])N=C([H])C([H])=C2[H])C2=C([H])C([H])=C([H])C(Cl)=C12
[H]N(C(=O)C([H])([H])OC(=O)C1=C2C(=NC3=C([H])C([H])=C([H])C([H])=C13)\C(=C(/[H])C1=C([H])C([H])=C([H])O1)C([H])([H])C2([H])[H])[C@]1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C([H])([H])[H]
[H]N(C(=O)C1=C(N(N=C1[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C(F)(F)F)C1=C([H])C([H])=C(OC2=C([H])C([H])=NC3=C2SC(=C3[H])C2=C([H])N(C([H])=N2)C([H])([H])[H])C(F)=C1[H]
[H]N1C([H])([H])C([H])([H])N(C(=O)C2=C(OC3=C(C([H])=C([H])C([H])=C3C([H])([H])[H])C([H])([H])[H])N(C3=C([H])C([H])=C([H])N=C23)C2=C([H])C([H])=C([H])C([H])=C2[H])[C@@]([H])(C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C1([H])[H]
[H]N(C(=O)C1=C([H])C2=C(SC(Cl)=C2[H])N1[H])[C@]1([H])C(=O)N(C2=C(C([H])=C([H])C([H])=C2[H])C1([H])[H])C([H])([H])C([H])([H])OC([H])([H])[H]
[H]N(C(=O)N([H])C1=NC([H])=C([H])C([H])=C1[H])C1=NC2=C([H])C([H])=C(C([H])=C2S1)C(=O)N([H])C1=C(C([H])=C([H])C([H])=C1Cl)C([H])([H])[H]
[H]OC1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[C@]1([H])N([H])C(=O)[C@]([H])(N([H])[H])C([H])([H])SSC([H])([H])[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C1=O)[C@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C(=O)N([H])[H])C([H])([H])C(=O)N([H])[H])C(=O)N1C([H])([H])C([H])([H])C([H])([H])[C@]1([H])C(=O)N([H])[C@]([H])(C(=O)N([H])C([H])([H])C(=O)N([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N([H])C1=NN([H])C2=C1C([H])=C(C([H])=C2[H])C1=C([H])C([H])=NC([H])=C1[H]
[H]N1C(=C([H])C2=C1C(=O)N(C(=O)N2[H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C(OC([H])([H])[H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H])C1=C([H])C(Cl)=C([H])C([H])=C1[H]
[H]OC(=O)C1=C(Cl)C([H])=C([H])C(=C1[H])C1=C([H])C([H])=C(O1)C(\[H])=C1/N([H])C(=O)N(C1=O)C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)C1=C([H])C([H])=C(O1)C1=C([H])C(Cl)=C([H])C([H])=C1Cl)C1=C(F)C([H])=C([H])C([H])=C1F
[H]N(C(=S)N([H])[C@]1([H])C2=C(C(OC([H])([H])[H])=C(N([H])S(=O)(=O)C([H])([H])[H])C([H])=C2[H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])C(SC2=C(Cl)C([H])=C(C#N)C([H])=C2[H])=C(C([H])=C1[H])C([H])([H])[H]
[H]N([H])C(=NC([H])([H])C([H])([H])C([H])([H])[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)C1=C(OC(=N1)[C@@]([H])(N([H])C(=O)C([H])([H])N([H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(F)C([H])=C1[H])C([H])([H])[H])C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C(=O)N([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])N([H])[H]
[H]N1N=C(C([H])=C1C(=O)OC([H])([H])[H])C1=C(Cl)C(Cl)=C(Cl)C([H])=C1[H]
[H]N(C1=C([H])C(=C([H])C([H])=N1)C1=C(N=C(N1[H])[S@](=O)C([H])([H])[H])C1=C([H])C([H])=C(F)C([H])=C1[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N([H])C1=NC(N([H])[H])=C(F)C(C2=NC(=C(N2[H])C2=C([H])C([H])=C([H])O2)C2=C([H])C([H])=NC([H])=C2[H])=C1F
[H]C1=C([H])C(F)=C(C([H])=C1[H])C([H])([H])N1C(=O)N(C(=O)C11C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C(C([H])=C2[H])C2=C([H])C([H])=C([H])C(C#N)=C2[H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C([H])C(OC([H])([H])[H])=C1[H]
[H]N(C(=O)C([H])([H])[H])C([H])([H])C([H])([H])C1=C(N([H])C2=C1C([H])=C([H])C([H])=C2[H])C([H])([H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]OP(=O)(O[H])OC([H])([H])[C@@]12C([H])([H])[C@]1([H])[C@]([H])(N1C([H])=NC3=C(N=C(Br)N=C13)N([H])C([H])([H])[H])C([H])([H])[C@]2([H])OP(=O)(O[H])O[H]
[H]C1=NC(=C([H])C([H])=C1[H])N1C([H])([H])C([H])([H])C([H])(C2=NN=C(N2C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N(C1=NC(=C([H])C(=N1)C(F)(F)F)C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)C([H])([H])[H])C([H])([H])C1([H])C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]N([H])C1=NC(=O)\C(N1[H])=C1\C2=C(N([H])C(=C2[H])C2=C([H])C([H])=C(OC([H])([H])[H])C([H])=C2[H])C(=O)N([H])C([H])([H])C1([H])[H]
[H]C1([H])OC([H])([H])C([H])([H])N(C2=NC(=NC(=N2)C#N)N2C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])C1([H])[H]
[H]OP(=O)(O[H])C([H])(C([H])([H])C([H])([H])C([H])([H])C([H])=C(C([H])([H])[H])C([H])([H])[H])P(=O)(O[H])O[H]
[H]OC(=O)C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C1=C(SC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C2=C([H])C(OC([H])([H])C3=C([H])C([H])=C(C([H])=N3)C([H])([H])C([H])([H])[H])=C([H])C([H])=C2N1C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C(OC([H])([H])[H])N=C1[H]
[H]N([H])C1=NC2=C(N=C(C([H])=C2[H])C([H])([H])N(C2=C([H])C([H])=C(OC([H])([H])[H])C([H])=C2OC([H])([H])[H])C([H])([H])[H])C(=N1)N([H])[H]
[H]N(C(=O)OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C(F)(F)C(=O)[C@@]([H])(N([H])C(=O)[C@@]1([H])N(C(=O)[C@@]([H])(N([H])C(=O)OC2=C([H])C([H])=C([H])C([H])=C2[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C1([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]OC1=C([H])OC(=C([H])C1=O)C([H])([H])SC([H])([H])C([H])([H])C([H])([H])[H]
[H]S\C(=N\C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])N1C([H])([H])C([H])([H])N(C2=C3C([H])=C(OC([H])([H])[H])C(OC([H])([H])[H])=C([H])C3=NC([H])=N2)C([H])([H])C1([H])[H]
[H]C1=C([H])C(=C([H])O1)C([H])([H])N(C(=O)O[C@@]1([H])C([H])([H])[C@@]2([H])N(C([H])([H])[H])[C@]([H])(C([H])([H])C2([H])[H])C1([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]O[C@@]([H])(C([H])([H])C(=C([H])[H])C(=O)N([H])C([H])([H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])N([H])C([H])=N1)C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]OC(=O)C(=C(/[H])C1=C(OC2=C([H])C([H])=C(Cl)C(=C2[H])C([H])([H])[H])C2=C([H])C(OC([H])([H])C3=C([H])C([H])=C(C([H])=C3[H])C3=C([H])C([H])=C([H])C([H])=C3[H])=C(OC([H])([H])C3=C([H])C([H])=C(C([H])=C3[H])C3=C([H])C([H])=C([H])C([H])=C3[H])C([H])=C2S1)\C1=C([H])C([H])=NC([H])=C1[H]
[H]N([H])C(=NC([H])([H])C([H])([H])C([H])([H])[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@]([H])(N([H])S(=O)(=O)C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H])C(=O)C1=NC([H])=C([H])S1)N([H])[H]
[H]OC(=O)C([H])([H])[C@]1([H])N([H])C(=O)C([H])([H])N([H])C(=O)[C@@]([H])(N(C(=O)[C@@]([H])(N([H])C(=O)C([H])([H])[H])C(SSC(C([H])([H])[H])(C([H])([H])[H])[C@@]([H])(N([H])C1=O)C(=O)N([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])N=C(N([H])[H])N([H])[H]
[H]N([H])C([H])([H])[C@@]1([H])C([H])([H])C([H])([H])[C@]([H])(C([H])([H])N([H])C2=NC(=NC([H])=C2[N+]([O-])=O)N([H])C([H])([H])C2=C([H])C([H])=C([H])C(F)=C2F)C([H])([H])C1([H])[H]
[H]C1=C(OC(=O)C([H])([H])[H])C(OC(=O)C([H])([H])[H])=C([H])C(=C1[H])C1=C([H])C(=O)C2=C(O1)C([H])=C(OC([H])([H])[H])C(OC([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])=C2OC([H])([H])[H]
[H]N(C1=NC([H])=C([H])C([H])=N1)C([H])([H])C([H])([H])OC1=NC([H])=NC(N([H])S(=O)(=O)C2=C([H])C([H])=C(C([H])=C2[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])=C1OC1=C([H])C([H])=C([H])C(OC([H])([H])[H])=C1[H]
[H]N1C(=O)C2=C(C1=O)C1=C(C([H])=C([H])C3=C1N(C([H])=C3[H])C([H])([H])[H])C1=C2C2=C(N1[H])C(Br)=C([H])C([H])=C2[H]
[H]N(C(=O)N([H])[C@@]([H])(C(=O)N1C([H])([H])C([H])([H])C([H])(N([H])C(=O)C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H])C([H])([H])C([H])([H])C(=O)OC([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C(=C([H])C([H])=C1[H])C([H])([H])[H]
[H]ON([H])C(=O)C1=C(Br)C([H])=C([H])C(N2C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C2([H])[H])=C1N(C([H])([H])[H])S(=O)(=O)C1=C([H])C([H])=C(OC([H])([H])C#CC([H])([H])[H])C([H])=C1[H]
[H]O[C@@]1([H])[C@@]([H])(O[C@]([H])(C([H])([H])O[P@@](=O)(O[H])O[P@@](=O)(O[H])O[P@@](=O)(O[H])O[P@@](=O)(O[H])OC([H])([H])[C@@]2([H])O[C@]([H])(O[H])C([H])([H])[C@@]([H])(O[H])[C@]2([H])O[H])[C@@]1([H])O[H])N1C([H])=C([H])C(=O)N([H])C1=O
[H]N([H])C(=O)C1=C([H])C(=C([H])C(=C1[H])C(=O)N1C([H])([H])C([H])([H])C([H])(C2=C([H])C([H])=C([H])C(=C2[H])C([H])([H])N([H])[H])C([H])([H])C1([H])[H])C1=NC(=NO1)C1=C([H])C([H])=C([H])S1
[H]C1=C2N(C(=O)SC2=C([H])C(=C1[H])C(=O)C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]C1=NC(OC2=C([H])C([H])=C(OC(=O)N3C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@@]3([H])C([H])([H])[H])C([H])=C2[H])=C([H])C([H])=C1C(F)(F)F
[H]N1C(=NC([H])([H])C1([H])[H])[C@]1([H])OC2=C([H])C([H])=C([H])C([H])=C2OC1([H])[H]
[H]N(C(=O)OC1=C([H])C([H])=C([H])C(=C1[H])C([H])([H])C(=O)N([H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]N(C(=O)C([H])([H])C([H])([H])[C@@]1(C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])N(C(=O)N([H])C2=C([H])C([H])=C(Cl)C([H])=C2[H])C([H])([H])C([H])([H])C1([H])[H])C1=NN([H])N([H])N1[H]
[H]OC1=C([H])C(O[H])=C(Cl)C([H])=C1C1=NN([H])C([H])=C1N1C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])N([H])C1=NC(=C([H])C2=C([H])N=C([H])C([H])=C12)C1=C([H])C([H])=NC([H])=C1F
[H]O[C@@]1([H])C([H])=C([H])[C@@]23C4=C(C([H])=C([H])C(OC([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[N+](C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])=C4O[C@@]2([H])C1([H])[H])C([H])([H])N(C([H])([H])[H])C([H])([H])C3([H])[H]
[H]N1C2=C(O[C@]([H])(C([H])([H])[H])C1([H])[H])C([H])=NC1=C2C2=C(S1)C(=O)N(C([H])=N2)C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]OC(=O)C([H])([H])C([H])([H])[C@]([H])(N([H])C(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])N=C1[H])C([H])([H])C1=C([H])C([H])=C(OC([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])=C1[H]
[H]N(C1=NC(=O)\C(S1)=C(/[H])\C(=C(\[H])C1=C([H])C([H])=C([H])C([H])=C1[H])\C([H])([H])[H])C1=C([H])C([H])=C(C(=C1[H])C([H])([H])[H])C([H])([H])[H]
[H]N1C([H])([H])[C@@]2([H])N(C3=C(C(Cl)=C([H])C([H])=C3C2([H])[H])C([H])([H])[H])[C@]([H])(C([H])([H])[H])C1([H])[H]
[H]ON(C(=O)N(C1=C([H])C(=C([H])C(OC([H])([H])C([H])([H])C([H])([H])[H])=C1OC([H])([H])C([H])([H])C([H])([H])[H])[C@]1([H])O[C@@]([H])(C2=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C(OC([H])([H])[H])=C2[H])C([H])([H])C1([H])[H])C([H])([H])C([H])([H])[H])C([H])([H])[H]
[H]N(\N=C1/C([H])([H])C([H])([H])C([H])([H])[C@]1([H])C([H])([H])[H])C1=NC(=C([H])S1)C1=C([H])C([H])=C([H])C(OC([H])([H])[H])=C1[H]
[H]O[C@]([H])(C([H])([H])OC1=C([H])C([H])=C([H])C([H])=C1C(=O)C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C(C([H])=C([H])C([H])=C2[H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]OC1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[C@]([H])(N([H])C([H])([H])[H])C(=O)N([H])C([H])([H])C(=O)N([H])C([H])([H])C(=O)N([H])[C@@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])N=C(N([H])[H])N([H])[H])C([H])([H])C([H])([H])C([H])([H])N=C(N([H])[H])N([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]O\C(=C(\C#N)C(=O)N([H])C1=C([H])C(C(=O)OC([H])([H])[H])=C(OS(=O)(=O)C(F)(F)F)C([H])=C1[H])C([H])([H])C([H])([H])[H]
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[H]OC1=C(OC([H])([H])[H])C([H])=C([H])C(=C1[H])C([H])([H])N([H])C(=O)N([H])C([H])([H])C([H])([H])C([H])([H])C(\[H])=C(\[H])C([H])([H])C(\[H])=C(\[H])C([H])([H])C(\[H])=C(\[H])C([H])([H])C(\[H])=C(\[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]OC(=O)C([H])([H])C([H])([H])SC1=NC(N([H])S(=O)(=O)C2=C([H])C([H])=C(C([H])=C2[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])=C(OC2=C([H])C([H])=C([H])C([H])=C2OC([H])([H])[H])C(OC([H])([H])C([H])([H])OC2=NC([H])=C(Br)C([H])=N2)=N1
[H]N1C2=C([H])C([H])=C1\C(=C1/N([H])\C(\C([H])=C1[H])=C(/C1=N/C(/C([H])=C1[H])=C(\C1=N\C(\C([H])=C1[H])=C2\C1=C([H])C(F)=C([H])C([H])=C1[H])C1=C([H])C(F)=C([H])C([H])=C1[H])C1=C([H])C(F)=C([H])C([H])=C1[H])C1=C([H])C(F)=C([H])C([H])=C1[H]
[H]OC(=O)[C@]1([H])N(C(=O)[C@@]([H])(N([H])C(=O)C([H])([H])N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)C2=C([H])C3=C(C([H])=C2[H])C(=O)C(=O)C2=C3C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C(=O)N([H])[H])C([H])([H])C([H])([H])C(=O)N([H])[H])C([H])([H])C([H])([H])C(=O)N([H])[H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])[C@@]1([H])C([H])([H])C2=C([H])C([H])=C([H])C(OC([H])([H])[H])=C2C([H])([H])C1([H])[H]
[H]OC1=C(C2=NC3=C([H])C([H])=C(N([H])C3=N2)N2C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])C(N([H])[H])=C2C([H])=C([H])C([H])=C([H])C2=N1
[H]C1=NC2=C(N1C([H])([H])[H])C(=O)N(C(=O)N2C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C(=O)OC([H])([H])C([H])([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])OC1=C([H])C([H])=C(OC([H])([H])C([H])([H])C([H])([H])C([H])([H])S(F)(=O)=O)C([H])=C1[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])[C@]1([H])C([H])([H])C([H])([H])[C@]2([H])N(C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])[C@@]1([H])N(C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C(=O)N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H])C2([H])[H]
[H]N(C1=C2C([H])=C(C([H])=C([H])C2=NC([H])=N1)[N+]([O-])=O)C1=C([H])C([H])=C([H])C(Br)=C1[H]
[H]N([H])C(=NC(=O)C1=C(N([H])C(=N1)C1=C([H])C(F)=C([H])C([H])=C1OC([H])([H])[H])C([H])([H])[H])N([H])[H]
[H]O[C@@]([H])(C([H])([H])C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])[C@@]([H])(N([H])C(=O)C([H])([H])C([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])OC([H])([H])C1=C([H])C([H])=C(Br)C([H])=C1[H]