[H]ON(C(=O)N([H])C([H])([H])C1=NC([H])=C(C([H])=C1F)C1=C([H])C(Cl)=C([H])C(F)=C1C1=NN(N=N1)C([H])([H])[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C1=NC(=C([H])S1)C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C([H])C2=C1C([H])([H])C([H])([H])C([H])([H])C2([H])[H]
[H]O[C@]([H])(C([H])([H])N([H])[C@]([H])(C(=O)N([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])[H])[C@@]([H])(N([H])C(=O)C1=C([H])C(=C([H])C([H])=C1[H])S(=O)(=O)C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)C([H])([H])[H])C1=C([H])C(=C([H])C([H])=C1[H])C1=C([H])C2=C([H])C([H])=C(OC([H])([H])[H])C([H])=C2C(=C1[H])C([H])([H])C([H])([H])N([H])C(=O)C([H])([H])[H]
[H]N([H])C1=C2C(OC([H])([H])C([H])([H])C2([H])[H])=NC2=C([H])C([H])=C(Cl)C([H])=C12
[H]N(C(=O)C([H])([H])[H])[C@@]1([H])C([H])([H])C([H])([H])[C@]([H])(N2C(=NC3=C([H])N=C4N([H])C([H])=C([H])C4=C23)C([H])([H])[H])C([H])([H])C1([H])[H]
[H]\C(=C(\[H])C1=C(C(=O)C(=C(C1=O)C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])N=C1[H])C([H])([H])[H])C(=O)OC([H])([H])C([H])([H])[H]
[H]N1C(=S)N(C2=C([H])C([H])=C(C([H])=C2[H])C([H])([H])C([H])([H])[H])C([H])([H])N(C([H])([H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C1([H])[H]
[H]O[C@@]1([H])[C@@]([H])(O[C@]([H])(C(=O)N([H])C([H])([H])C([H])([H])[H])[C@@]1([H])O[H])N1C([H])=NC2=C(N=C([H])N=C12)N([H])C(=O)N([H])C1=C([H])C(=C([H])C([H])=C1[H])C(F)(F)F
[H]N([H])C1=C(C([H])=NC2=C(C([H])=NN12)C1=C([H])C([H])=C([H])C(=C1[H])N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C(N([H])C(=O)N(C([H])([H])[H])C2([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])=C1[H]
[H]N([H])C1=C(Cl)C([H])=C(C(=O)N([H])C2([H])C([H])([H])C([H])([H])N(C([H])([H])C3([H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])N([H])[H])C([H])([H])C3([H])[H])C([H])([H])C2([H])[H])C(OC([H])([H])[H])=C1[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])OC1=C([H])C(=C([H])C([H])=C1OC([H])([H])[H])C([H])([H])[C@@]([H])(N(C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]C1=NC2=C(C(=NN2C([H])([H])[H])C2=C([H])C([H])=C([H])C(Br)=C2[H])C(=N1)C#CC1=C([H])N=C(C([H])=C1[H])N(C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])N2C(=NC(OC([H])([H])N3C(=O)C4=C(C([H])=C(OC([H])([H])[H])C([H])=C4S3(=O)=O)C([H])(C([H])([H])[H])C([H])([H])[H])=C(Br)C2=O)C([H])=C1[H]
[H]C1=C(Cl)N(C2=NC(=C(N12)C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C([H])([H])[H])C(F)(F)F)C1=C(C([H])=C(C([H])=C1C([H])([H])[H])C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])C(=NC(=N1)C1=C([H])C([H])=C(Cl)C([H])=C1[H])N1C([H])([H])C([H])([H])C([H])([H])[C@]([H])(N2C(=O)N(C3=C2C([H])=C([H])C([H])=C3[H])C([H])([H])C([H])([H])[H])C1([H])[H]
[H]C1=C([H])C([H])=C2N(C(=NC2=C1[H])[C@]1([H])C([H])([H])N(C([H])([H])C([H])([H])C1([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]OC(=O)C([H])([H])C1=C(N(C(=O)C2=C([H])C([H])=C(I)C([H])=C2[H])C2=C1C([H])=C(OC([H])([H])[H])C([H])=C2[H])C([H])([H])[H]
[H]N(C(=O)C1=C([H])N(C(=N1)C([H])([H])C([H])([H])C([H])([H])[H])C1=C([H])C([H])=C(F)C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C([H])C([H])=C([H])C(=C2C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]OC1=C([H])C([H])=C(\C([H])=C(/[H])C(=O)C2=C([H])C([H])=C(O[H])C([H])=C2O[H])C([H])=C1[H]
FC1=CC=C(C=C1F)C(=O)CC1=CC=C(C=C1)C1=NN=C2N1C1=CC=CN=C1NC1=C2C=CC=C1
[H]C1=C([H])C(OC([H])([H])[H])=C(SC2=C([H])C(=C(C#N)C([H])=C2[H])C(F)(F)F)C([H])=C1[H]
[H]OC(=O)C([H])([H])C1=C([H])C(Cl)=C(OC([H])([H])C2=C([H])C(=C([H])C(=C2[H])C2=C([H])C([H])=C(C([H])=C2[H])C(F)(F)F)C2=C([H])C([H])=C(C([H])=C2[H])C(F)(F)F)C([H])=C1[H]
[H]C1=C(N(N=C1C([H])([H])C([H])([H])C(=O)N1C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C(C([H])=C2[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C(Cl)C([H])=C1[H])C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]N(C(=O)N1OC(=O)C(=C1C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]O[C@@]1([H])C([H])([H])C(=O)O[C@@]([H])(C(\[H])=C(/[H])C2=C(C([H])=C(Cl)C([H])=C2Cl)C([H])([H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C1([H])[H]
[H]N([H])C1=NC(=C([H])C([H])=N1)C1=C([H])C2=C(N1[H])C([H])([H])C([H])([H])N([H])C2=O
[H]N([H])C1=C(I)C([H])=C(C([H])=C1I)S(=O)(=O)N([H])[H]
[H]N(C(=O)C1=C(C([H])=C([H])C([H])=C1[H])C1=NN([H])N=N1)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1C(=NN=C1C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])[S@](=O)C([H])([H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]OC(=O)C([H])([H])C([H])([H])C(=O)O[C@@]1([H])C2=C(C([H])=C3OC([H])([H])OC3=C2[H])[C@@]([H])(C2=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C(OC([H])([H])[H])=C2[H])[C@@]2([H])C(=O)OC([H])([H])[C@]12[H]
[H]OC([H])([H])C([H])([H])N([H])C1=NC2=C(C([H])=C([H])C([H])=C2[H])C(=N1)N([H])C1=C([H])C([H])=C([H])C([H])=C1C([H])([H])[H]
[H]OC([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC2=C(C([H])=C([H])C([H])=C2N1[H])C(=O)N([H])[H]
[H]OC([H])([H])C([H])([H])N1C([H])=C([H])C2=NC([H])=NC(N([H])C3=C([H])C([H])=C(OC4=C([H])C([H])=C([H])C5=C4C([H])=NS5)C(Cl)=C3[H])=C12
[H]C1=C([H])C([H])=C2C(=C1[H])N(C(=O)C1=C(Cl)C([H])=C(C([H])=C1[H])N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H]
[H]OC(=O)[C@@]([H])(C([H])([H])C([H])([H])[H])[C@]1([H])C2=C([H])C([H])=C(OC([H])([H])C([H])([H])C3=C(OC(=N3)C3=C([H])C4=C(OC([H])([H])O4)C([H])=C3[H])C([H])([H])[H])C([H])=C2C([H])([H])C1([H])[H]
[H]OC([H])([H])[C@@]1([H])O[C@@]([H])(N2C([H])=NC3=C2N=C([H])N=C3N([H])C2([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])[C@]([H])(O[H])[C@@]1([H])N([H])C(=O)C1=C([H])C([H])=C(C(=C1[H])C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)C([H])([H])N1C(Cl)=C([H])N=C(N([H])C([H])([H])C(F)(F)C2=[N+]([O-])C([H])=C([H])C([H])=C2[H])C1=O)C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1OC([H])([H])C(F)(F)F
[H]ON([H])C(=O)[C@]1([H])N(C([H])([H])C2=C(C([H])=C([H])C([H])=C2[H])C1([H])[H])S(=O)(=O)C1=C([H])C([H])=C(S1)C#CC1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]N([H])S(=O)(=O)C1=C([H])C([H])=C(C#CC2=C([H])N(C(=O)C([H])=C2[H])C([H])(F)F)C([H])=C1[H]
[H]OC1=C([H])C([H])=C([H])C([H])=C1SC1=NN2C([H])=NC(=O)C(=C2C([H])=C1[H])C1=C(Cl)C([H])=C([H])C([H])=C1Cl
[H]N(C(=O)N1C([H])([H])[C@@]([H])(C([H])=C2C3=C([H])C([H])=C([H])C4=C3C(=C([H])N4C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H])C([H])([H])[C@@]12[H])C(=O)N1C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)C1=C([H])C(OC([H])([H])C([H])([H])C2=C([H])C([H])=C(Cl)C([H])=C2Cl)=C(OC([H])([H])[H])C([H])=C1[H])C([H])([H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]O[C@]([H])(C([H])([H])N([H])C([H])([H])[H])[C@@]([H])(N1C([H])=C([H])C2=C1C([H])=C([H])C([H])=C2C([H])([H])[H])C1=C([H])C(F)=C([H])C([H])=C1[H]
[H]OC1(C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])[C@@]([H])(C1=C([H])C([H])=C([H])C([H])=C1OC([H])([H])[H])C([H])([H])N([H])C(=O)C([H])([H])C1=C([H])C(=C([H])C(=C1[H])C(F)(F)F)C(F)(F)F
[H]N1C([H])=NC(=C1[H])C([H])([H])C([H])([H])C([H])([H])OC(=O)C([H])([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C(I)C([H])=C1[H]
[H]C1=NN(C(=N1)C(C([H])([H])[H])(C([H])([H])[H])[C@]1([H])C2=C([H])C(=C(Cl)C([H])=C2[C@@]2(C1([H])[H])C([H])([H])C([H])([H])N(C(=O)[C@]1([H])C([H])([H])[C@]([H])(N(C([H])([H])[H])C3([H])C([H])([H])C([H])([H])OC([H])([H])C3([H])[H])C([H])([H])[C@@]1([H])C1=C([H])C([H])=C(F)C([H])=C1F)C([H])([H])C2([H])[H])C([H])([H])[H])C([H])([H])[H]
[H]N(C1=C([H])C([H])=C([H])C(=N1)C1=C([H])N=C2C([H])=C([H])C(=C([H])N12)C1=C([H])C([H])=C([H])N1[H])C1([H])C([H])([H])C([H])([H])N([H])C([H])([H])C1([H])[H]
[H]N(C(=O)OC([H])([H])C1(C([H])([H])OC2=NC(=C([H])S2)C2=C([H])C([H])=C(C([H])=C2[H])C([H])([H])[H])C([H])([H])C([H])([H])C1([H])[H])[C@]([H])(C(=O)C(=O)N([H])[C@@]([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]N([H])S(=O)(=O)OC1=C([H])C([H])=C(C([H])=C1C#N)C([H])([H])N(N1C([H])=NN=C1[H])C1=C([H])C([H])=C(C#N)C([H])=C1[H]
[H]N([H])C1=NC2(N([H])C3=C([H])C([H])=C([H])C(Cl)=C13)C([H])([H])C([H])([H])N(C(=O)OC([H])([H])C([H])([H])[H])C([H])([H])C2([H])[H]
[H]OC1=C([H])C([H])=C([H])C2=C1N(C1=C2C2=C(C(=O)N(N([H])C([H])(C([H])([H])O[H])C([H])([H])O[H])C2=O)C2=C1N([H])C1=C2C([H])=C([H])C([H])=C1[H])[C@]1([H])O[C@]([H])(C([H])([H])O[H])[C@@]([H])(O[H])[C@@]([H])(O[H])[C@]1([H])O[H]
[H]C1=C([H])C([H])=C2C(SN=C2N2C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])C([H])([H])N3C(=O)SC4(C3=O)C([H])([H])C([H])([H])C([H])([H])C4([H])[H])C([H])([H])C2([H])[H])=C1[H]
[H]C1=C([H])C(OC([H])([H])C([H])([H])C([H])([H])N2C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])=C2N(C([H])([H])C3([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C3([H])[H])C([H])([H])C([H])([H])C([H])([H])C2=C1[H]
[H]N(C(=O)C1=C([H])C2=C([H])C([H])=C([H])C([H])=C2S1)C1=C([H])C([H])=C2N=C(C([H])=C(C2=C1[H])C([H])([H])[H])N(C([H])([H])[H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)C1=C([H])N=C([H])N(C1=O)C([H])([H])C1=C([H])C([H])=C(F)C(F)=C1[H])C([H])([H])C#CC1=C([H])C([H])=C2N=C([H])C(=C([H])C2=C1C([H])([H])[H])C(=O)N(C([H])([H])[H])C([H])([H])[H]
[H]O[C@]([H])(C([H])([H])C([H])([H])C([H])([H])N([H])C(=O)N([H])C1=C([H])C(Cl)=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]N(C1=NC(=NC2=C1N(C(=O)N2C1=C([H])C([H])=C(C([H])=C1Br)C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])OC([H])([H])[H]
[H]C1=NC2=C([H])C([H])=C([H])C([H])=C2C(=O)N1C([H])([H])C([H])([H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]C1=C(ON=C1C(=O)N1C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])C([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]N(C(=O)C(=O)C1=C(N([H])C2=C([H])C([H])=C([H])C([H])=C12)C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])N([H])C1=C([H])C([H])=C(C2=NON=C12)[N+]([O-])=O
[H]C1=C([H])C(=C([H])C(=C1[H])C(=O)\N=C1/SC(=C(N1C([H])([H])C1([H])C([H])([H])C1([H])[H])C([H])([H])[H])C([H])([H])[H])C(F)(F)F
[H]OC1=C([H])C2=C(C([H])=C1[H])C(=O)[C@]1([H])N(C([H])([H])C3([H])C([H])([H])C3([H])[H])C([H])([H])[C@]([H])(C([H])([H])C([H])([H])[H])[C@@]2([H])[C@@]1([H])C([H])([H])[H]
[H]C1=C(C(=O)C2([H])C(C([H])([H])[H])(C([H])([H])[H])C2(C([H])([H])[H])C([H])([H])[H])C2=C([H])C3=C(OC([H])([H])O3)C([H])=C2N1C([H])([H])C1([H])C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
ClC1=CC=C(C=C1)C1=C[N-]C(=N1)[C@@H]1CC2=CC=CC=[C]2=CN1
[H]OC1=C(N([H])S(=O)(=O)C([H])([H])[H])C([H])=C(C([H])=C1[H])[C@]([H])(O[H])C([H])([H])N([H])[C@@]([H])(C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C(=O)N([H])C([H])([H])[H]
[H]OP(=O)(O[H])C([H])([H])N1C(=O)C(=O)N([H])C2=C([H])C(=C(C([H])=C12)C([H])([H])[H])C([H])([H])[H]
[H]OC(=O)C([H])([H])C([H])([H])[C@@]([H])(C(=O)O[H])C([H])([H])C([H])([H])C([H])([H])S[H]
[H]C1=NC([H])=C(N1C([H])([H])[H])[C@@]([H])(OC([H])([H])C1=NC(=C(C#N)C([H])=C1[H])C1=C([H])C([H])=C(Cl)C([H])=C1[H])C1=C([H])C([H])=C(C#N)C([H])=C1[H]
CN1CCC(CC1)N1CCC(CC1)N1N=C(C2=C(N)N=CN=C12)C1=CC=C(NC2=NC3=C(O2)C(Cl)=CC=C3)C=C1
[H]N(\C(=N/C#N)N1C([H])([H])C([H])([H])N(C(=O)C([H])([H])C2=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C([H])=C2[H])C([H])([H])[C@@]1([H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C1=C(C([H])=C([H])C([H])=C1[H])C([H])([H])[H]
[H]N1C(=O)C2(N(C3=C([H])C([H])=C([H])C([H])=C3[H])C1([H])[H])C([H])([H])C([H])([H])N(C([H])([H])C2([H])[H])[C@@]([H])(C1=C([H])C([H])=C(Cl)C([H])=C1[H])C([H])([H])[H]
[H]N([C@@]([H])(C1=NN(C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C(F)(F)F)C([H])([H])[H])[C@@]([H])(C1=C([H])C(F)=C([H])C([H])=C1[H])C([H])([H])[H]
[H]N(C(=O)C1=C([H])C2=C(N=C(N2C([H])([H])C2=C([H])C([H])=C(C([H])=C2[H])C2=C([H])C([H])=C([H])C([H])=C2C2=NN=NN2[H])C([H])([H])C([H])([H])C([H])([H])[H])C(=C1[H])C([H])([H])[H])C([H])([H])[C@]([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H]
[H]C1=C([H])C(N(C([H])([H])[H])C([H])([H])[H])=C2C(SC3=C2C([H])=C([H])N(C3=O)C2=C([H])C([H])=C(OC([H])([H])[H])C([H])=C2[H])=N1
[H]N1C([H])=NC([H])=C1\C([H])=C1\C2=C([H])C([H])=C(F)C([H])=C2C([H])([H])C1([H])[H]
[H]N([H])C1=NC(N(C(=N1)N([H])[H])C1=C([H])C(=C([H])C([H])=C1[H])C([H])([H])OC1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]\C(=C1\OC2=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C([H])=C2C1=O)C1=C([H])C([H])=C([H])C(=C1[H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(C(=O)C([H])([H])N1C(=O)C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C(OC([H])([H])[H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]OC(=O)[C@@]1([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])OC([H])([H])C([H])=C(C2=C(C([H])=C([H])C([H])=C2[H])C([H])([H])[H])C2=C(C([H])=C([H])C([H])=C2[H])C([H])([H])[H])C([H])([H])C([H])([H])C1([H])[H]
[H]OC1=C2C(=C([H])C([H])=C1C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])C([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C2([H])[H]
[H]N1N=C(N([H])C1=O)C1=C([H])C(=C([H])C(=C1[H])C(F)(F)F)S(=O)(=O)N1C([H])([H])C([H])([H])N(C(=O)[C@]2([H])C([H])([H])[C@@]2([H])C2=C([H])C([H])=C(C([H])=C2[H])C(F)(F)F)C([H])([H])C1([H])[H]
[H]N(C(=O)OC([H])([H])C1(C([H])([H])OC(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])[N+]2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]N(C1=NC2=C([H])C([H])=C(Cl)C([H])=C2S1)C1([H])C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C(OC([H])([H])[H])C(OC([H])([H])C([H])([H])[H])=C2[H])C([H])([H])C1([H])[H]
[H]ON([H])C(=O)[C@]([H])(N(C([H])([H])C1=C([H])C2=C(OC([H])([H])O2)C([H])=C1[H])S(=O)(=O)C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])C([H])([H])C([H])([H])C(=O)N1C([H])([H])C([H])([H])N(C(=O)OC([H])([H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N([H])S(=O)(=O)C1=C([H])C([H])=C(C([H])=C1[H])N1N=C(C2=C([H])C(Cl)=C([H])C([H])=C2[H])C([H])([H])[C@]1([H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]N(C(=O)[C@@]1([H])N(C2=NN3C([H])=C([H])C([H])=C3C(=N2)N([H])C2=NN([H])C(=C2[H])C2([H])C([H])([H])C2([H])[H])C([H])([H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H]
[H]N([H])[C@@]1([H])C([H])([H])N(C2=C([H])C([H])=C3N(N=C(C3=C2[H])S(=O)(=O)C2=C3C([H])=C([H])C([H])=C([H])C3=C([H])C([H])=C2[H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]O[C@]1([H])N(C(=N[H])N([H])[H])C([H])([H])C([H])([H])C([H])([H])[C@]1([H])N([H])C(=O)C([H])([H])N([H])C(=O)[C@]([H])(N([H])S(=O)(=O)C([H])([H])C1=C(C([H])=C([H])C([H])=C1[H])C(=O)OC([H])([H])[H])C([H])([H])[C@]1([H])C([H])([H])N(C(=N[H])N([H])[H])C([H])([H])C([H])([H])C1([H])[H]
[H]OC1=NC(=C(N1C1([H])C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H]
[H]N(C(=O)N([H])[C@@]1([H])C(=O)N(C([H])([H])C(=O)N([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])[C@@]([H])(C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])[C@@]([H])(C2=C(C([H])=C([H])C([H])=C2[H])C([H])([H])[H])C1([H])[H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])[C@@]1(O[C@]([H])(C([H])([H])[N+](C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])[S@@+]1[O-])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]OC([H])([H])[C@]([H])(N([H])C(=O)[C@]([H])(N([H])C(=O)[C@]([H])(N([H])C(=O)[C@]([H])(N([H])C(=O)C([H])([H])[H])C([H])([H])C1=C([H])C2=C([H])C([H])=C([H])C([H])=C2C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C(Cl)C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C([H])N=C1[H])C(=O)N([H])[C@]([H])(C(=O)N([H])[C@@]([H])(C(=O)N([H])[C@@]([H])(N(C(=O)C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C(=O)N([H])[C@]([H])(C(=O)N1C([H])([H])C([H])([H])C([H])([H])[C@]1([H])C(=O)N([H])[C@@]([H])(C(=O)N([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(N([H])C(=O)C([H])([H])[H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C(N([H])C(=O)C([H])([H])[H])C([H])=C1[H]
[H]N([H])S(=O)(=O)C1=NN=C(S1)N([H])C(=O)C([H])([H])C([H])([H])[C@@]([H])(C([H])([H])[H])[C@@]1([H])C([H])([H])C([H])([H])[C@@]2([H])[C@]3([H])C(=O)C([H])([H])[C@]4([H])C([H])([H])C(=O)C([H])([H])C([H])([H])[C@]4(C([H])([H])[H])[C@@]3([H])C([H])([H])C(=O)[C@]12C([H])([H])[H]
[H]N(C1=C(C([H])=C2N([H])N=C(\C([H])=C(/[H])C3=C([H])C([H])=C([H])C([H])=C3[H])C2=C1[H])N1C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=N1
[H]N([H])S(=O)(=O)N1N=C(C([H])=C1C1=C([H])C([H])=C(Cl)C([H])=C1[H])C([H])([H])OC1=C([H])C(=C([H])C(F)=C1[H])C1(OC([H])([H])[H])C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]O[C@@]1([H])C2=C(N([H])C([H])=NC1([H])[H])N(C([H])=N2)C([H])([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C(=C1[H])C([O-])=O
CC(=[Se])NCCCC[C@H](NC(=O)OCC1=CC=CC=C1)C(=O)NC1=CC=CC=C1
[H]C1=C([H])C2=C(S1)C1(OC([H])=C2[H])C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N(C1=C([H])C([H])=C2N([H])N=C(C2=C1[H])S(=O)(=O)C1=C([H])C([H])=C([H])C2=C([H])C([H])=C([H])C([H])=C12)[C@]1([H])C([H])([H])N([H])C([H])([H])C([H])([H])C1([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C(=O)C([H])([H])N1C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])OC([H])(C2=C([H])C([H])=C(F)C([H])=C2[H])C2=C([H])C([H])=C(F)C([H])=C2[H])C([H])([H])C1([H])[H]
[H]OC(=O)C([H])([H])[C@]([H])(N([H])C(=O)C1=C([H])N=C(C([H])=C1[H])C([H])([H])N([H])S(=O)(=O)C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])=O
[H]C1=C2N(C(=NC2=C([H])C(=C1[H])C(=O)N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(OC([H])([H])C([H])([H])[H])C([H])=C1[H])C([H])([H])[C@]1([H])OC([H])([H])C([H])([H])C1([H])[H]
[H]N(C(=O)N(C([H])([H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])S(=O)(=O)C([H])([H])[H])[C@]1([H])C([H])([H])C([H])([H])[C@]2(C3=C([H])C([H])=C([H])C(=C3[H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H])C([H])([H])[C@]2([H])C1([H])[H])C1=C([H])C(Cl)=C(F)C([H])=C1[H]
[H]N(C(=O)N([H])C([H])([H])C1(C2=C([H])C([H])=C(C([H])=C2[H])C2=C([H])C(C#N)=C([H])C([H])=C2[H])C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])[C@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])[H])C1=C([H])C(Cl)=C([H])C(Cl)=C1[H]
[H]S\C(=N/N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])N([H])C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)N([H])C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)N([H])[H]
[H]N([H])[C@@]([H])(C(=O)N1C([H])([H])C([H])([H])N(C2=C([H])C3=C(N([H])N=C3[H])C([H])=C2[H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C(Br)C([H])=C1[H]
[H]N(C(=O)C1=C([H])C([H])=C([H])C(=C1[H])S(=O)(=O)N([H])C1=C([H])C([H])=C(Br)C([H])=C1[H])C1=C([H])C([H])=C(Br)C([H])=C1[H]
[H]N(C(=O)C1=C(Cl)C(=C([H])S1)C([H])([H])OC([H])([H])C([H])([H])OC([H])([H])C([H])([H])OC([H])([H])[H])C1=C(C([H])=C(Cl)C([H])=C1[H])C(=O)N([H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]OC(=O)[C@@]1(F)[C@]2([H])C([H])([H])[C@@]([H])(OC([H])([H])C3=C(F)C(F)=C([H])C([H])=C3[H])[C@@](N([H])[H])(C(=O)O[H])[C@]12[H]
[H]N([H])C(=O)C([H])([H])N([H])[C@@]1([H])C([H])([H])C([H])([H])N(C(=O)C2=C([H])C(=C([H])C(=C2[H])C(F)(F)F)C(F)(F)F)[C@]([H])(C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C1([H])[H]
[H]N([C@]([H])(C1=NC2=C(N1[H])C([H])=C([H])C(Cl)=C2[H])C([H])([H])C1=C([H])C([H])=C(C(F)=C1[H])[C@]1([H])C([H])([H])C(=O)[N-]S1(=O)=O)S(=O)(=O)C1=C([H])C(=C([H])C([H])=C1[H])C(F)(F)F
[H]N([H])C1=NC2=C(C([H])=C(S2)C(=O)N([H])C([H])([H])C([H])([H])[H])C(=N1)C1=C([H])C(OC([H])([H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H])=C(Cl)C([H])=C1Cl
[H]N(C1=NC(N([H])C([H])([H])[H])=C(C([H])=N1)C(F)(F)F)C1=C([H])C(F)=C(C([H])=C1OC([H])([H])[H])C(=O)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]N([H])S(=O)(=O)C1=C([H])C(N([H])S(=O)(=O)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F)=C([H])C([H])=C1[H]
[H]N(C(=O)N1C([H])([H])C([H])([H])N(C2=NC([H])=NC3=C([H])C(OC([H])([H])[H])=C(OC([H])([H])C([H])([H])OC([H])([H])[H])C([H])=C23)C([H])([H])C1([H])[H])C1=C([H])C([H])=C(OC2=C([H])C([H])=C([H])C([H])=C2[H])C([H])=C1[H]
[H]C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])[C@@]([H])(C1([H])[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]C1=C([H])C(OC([H])([H])[H])=C(C([H])=C1[H])N1C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])[C@@]1([H])C([H])([H])[C@@]2([H])C([H])([H])[C@]([H])(N3C([H])([H])C([H])([H])N(C4=C(OC([H])([H])[H])C([H])=C([H])C([H])=C4[H])C([H])([H])C3([H])[H])C([H])([H])[C@@]2([H])C1([H])[H]
Cl.COC1=CC2=C(CN(CCC3=CC=C(NC(=O)C4=C5NC6=C(C=CC=C6OC)C(=O)C5=CC=C4)C=C3)CC2)C=C1OC
[H]N(C1=NC(=NC2=C1C([H])=C(N2C([H])([H])[H])C(=O)N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H])N1C([H])=NC2=C1C([H])=NC([H])=C2[H])C1=C(Cl)C([H])=C([H])C(OC([H])([H])[H])=C1[H]
[H]N(C(=S)N([H])[C@@]([H])(C1=C([H])C(OC([H])([H])[H])=C(N([H])S(=O)(=O)C([H])([H])[H])C([H])=C1[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]O[C@@]([H])(C1=C([H])SC2=C([H])C([H])=C([H])C([H])=C12)C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C([H])C([H])=C([H])C3=C2N=C([H])C([H])=C3[H])C([H])([H])C1([H])[H]
[H]OC(=O)C([H])([H])[C@]([H])(N([H])C(=O)C([H])([H])N(C(=O)C([H])([H])C1=C([H])C([H])=C(N([H])C(=O)N([H])C2=C([H])C([H])=C([H])C([H])=C2C([H])([H])[H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])OC([H])([H])[H])C1=C([H])C([H])=C(OC([H])([H])[H])C(OC([H])([H])[H])=C1[H]
[H]N([H])S(=O)(=O)C1=C([H])C([H])=C([H])C([H])=C1C1=C([H])C([H])=C(N([H])C(=O)C2=C([H])C(=NN2C2=C([H])C([H])=C(OC([H])([H])[H])C([H])=C2[H])C([H])([H])[H])C(F)=C1[H]
[H]OC1=C(OC([H])([H])[H])C(O[H])=C2C(=O)C([H])=C(OC2=C1OC([H])([H])[H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]OC([H])([H])[C@]12[C@@]3([H])N(C(=O)OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])[C@@]4([H])[C@]([H])([C@@]5([H])N(C(=O)OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])[C@]1([H])[C@]3([H])[C@@]([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])[C@@]45C([H])([H])O[H])[C@]2([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC1=C([H])C(=NC2=C([H])C([H])=C(OC([H])([H])[H])C([H])=C12)C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)N(C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C([H])C(C#N)=C1[H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C1=C([H])C(=C(F)C([H])=C1[H])C(F)(F)F
[H]C1=C([H])C2=C(Cl)C([H])=C([H])C([H])=C2C(Cl)=C1[H]
[H]N([H])C1=C([H])C([H])=C(C(=N1)C([H])([H])[H])C([H])([H])C(=O)C([H])([H])N1C(=O)[C@@]([H])(N([H])S(=O)(=O)C2=C([H])C3=C(OC([H])([H])C3([H])[H])C([H])=C2[H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]OC(=O)C([H])([H])C([H])([H])[C@]([H])(N([H])C(=O)C1=C([H])C(OC([H])([H])C([H])([H])C([H])([H])OC([H])([H])[H])=C([H])C(=N1)C1=C([H])C([H])=C([H])C([H])=C1[H])C(=O)N1C([H])([H])C([H])([H])N(C(=O)OC([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]O[C@]1([H])C([H])([H])O[C@]([H])(N2N=NC(=C2[H])C([H])([H])OC(=O)C2=C([H])C([H])=C(C([H])=C2[H])S(=O)(=O)N([H])[H])[C@@]([H])(O[H])[C@]1([H])O[H]
NC1(CCN(CC1)C1=NC=NC2=C1C=CN2)C(=O)NC(CCCN1CCCCC1)C1=CC=C(Cl)C=C1
[H]N([H])C1=NC2=C(OC([H])([H])C([H])([H])C(OC([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])=C([H])C([H])=C2C([H])=C1[H]
[H]N([H])C1=NC2=C(C(=O)C3=C([H])C([H])=C(C([H])=C23)C(=O)C2=C([H])N=C([H])C([H])=C2[H])C(=N1)C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC1=C([H])C([H])=C(N([H])C2=NC(=C([H])S2)C2=C([H])C3=C(OC2=O)C([H])=C([H])C(OC([H])([H])[H])=C3[H])C([H])=C1[H]
[H]N1C(=C([H])C2=C(C([H])=C([H])C([H])=C12)C([H])([H])N(C([H])([H])[H])C([H])([H])[H])C1=NC(=NO1)C([H])([H])C([H])([H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]C([H])=C([H])C1=C2C3=C4C(=C([H])C([H])=C3[H])C([H])([H])C([H])([H])N(C([H])([H])[H])[C@]4([H])C([H])([H])C2=C([H])C([H])=C1[H]
[H]OC1=C(C([H])=C([H])C([H])=C1C1=C([H])C(=C([H])C([H])=C1[H])C([H])([H])N([H])C(=O)N([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C1=C([H])C2=C([H])N=C([H])C([H])=C2N1[H]
[H]OP(=O)(O[H])C([H])([H])N([H])[C@]([H])(C(=O)N([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C2C([H])=C([H])C([H])=C([H])C2=C1[H])C([H])([H])C#CC1=C([H])C([H])=C(F)C([H])=C1F
[H]N1C2=C([H])C([H])=C(C([H])=C2C(=C([H])C1(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)C1=C(C([H])=C([H])S1)S(=O)(=O)N([H])C1=C(Cl)C(=NO1)C([H])([H])[H])C1=C(C([H])=C(C([H])=C1C([H])([H])[H])C([H])([H])[H])C(=O)C([H])(C([H])([H])[H])C([H])([H])[H]
[H]ON(C(=O)N([H])[H])C([H])([H])C1=C(OC([H])=C1[H])C([H])([H])[H]
[H]N(C(=S)N([H])C([H])([H])[C@@]([H])(C1=C([H])C([H])=C(C([H])=C1[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])OC(=O)C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C(F)=C(N([H])S(=O)(=O)C([H])([H])[H])C([H])=C1[H]
[H]OC(=O)C1=C(N([H])C(=O)C2=NC3=C(S2)C([H])([H])N(C([H])([H])C3([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])C(=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C(=O)N([H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]N1C([H])([H])C([H])([H])C([H])(C([H])([H])C([H])([H])OC2=C3N=C(N(C3=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C([H])([H])[C@]2([H])C([H])([H])N([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])OC2=C([H])C([H])=C(Cl)C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N1C2=C([H])C([H])=C(C([H])=C2C2(C1=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C1=C([H])C(=C([H])C([H])=C1[H])[N+]([O-])=O
[H]C1=NN2C(N=C(C([H])=C2N(C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[H])N(C2=C([H])C([H])=C(OC([H])([H])[H])C([H])=C2Cl)C([H])([H])C([H])([H])[H])=C1[H]
[H]N(C1=NC(Cl)=C([H])N(C1=O)C([H])(C([H])([H])OC([H])([H])[H])C([H])([H])OC([H])([H])[H])C1=C(C([H])=C(C([H])=C1C([H])([H])[H])C([H])([H])[H])C([H])([H])[H]
[H]N([H])C(N([H])C([H])([H])C1=NC(=C([H])C([H])=C1[H])C([H])([H])N([H])C(N([H])[H])=[N+]([H])[H])=[N+]([H])[H]
[H]OC(=O)[C@]([H])(OC1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C(=C([H])C([H])=C1[H])C1=C(OC(=N1)C1=C([H])C([H])=C(C([H])=C1[H])C(F)(F)F)C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)C1=C([H])C(OC([H])([H])C([H])([H])C2=C([H])C([H])=C(Cl)C([H])=C2Cl)=C(OC([H])([H])[H])C([H])=C1[H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]OC(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])O\N=C(\[C@]([H])(N1C([H])=NC([H])=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1F)C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(C(=O)N([H])C1=C(C([H])=C([H])C([H])=C1C([H])(C([H])([H])[H])C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])C1=NN(N=N1)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])O[C@@]1([H])OC([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(C(=O)C1=NN(C2=C([H])C([H])=C([H])C([H])=C12)C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])N2C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]N(C(=O)[C@]1([H])OC2=C([H])C([H])=C([H])C([H])=C2OC1([H])[H])C1=NC2=C(S1)C([H])=C(C([H])=C2[H])S(=O)(=O)C([H])([H])[H]
[H]N([H])C1=NC(N([H])C2=C([H])C([H])=C([H])C(Br)=C2[H])=C2C([H])=C(N([H])C2=N1)C([H])([H])C1=C([H])C(OC([H])([H])[H])=C([H])C([H])=C1OC([H])([H])[H]
[H]N(C(=O)OC([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])[C@]([H])(C(=O)N([H])[C@]([H])(C([H])=O)C([H])([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N1C(=O)C([H])=C([H])C2=C1C([H])=C(C([H])=C2[H])C1=NN=C(S1)N1C([H])([H])C([H])([H])C([H])(N2C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]C1=C([H])C2=C([H])C([H])=C(C([H])=C2C([H])=C1[H])[C@]([H])(C(=O)OC([H])([H])[H])[C@@]1([H])C([H])([H])C([H])([H])C([H])([H])[N+]1([H])[H]
[H]OC1=C([H])C2=C(C([H])=C1[H])C(C(=O)N1C([H])([H])C([H])([H])N([H])C([H])([H])C1([H])[H])=C(OC1=C(C([H])=C([H])C(F)=C1[H])C([H])([H])[H])N2C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]N([H])C1=NC(=O)\C(N1[H])=C1\C2=C(N([H])C([H])=C2[H])C(=O)N([H])C([H])([H])C1([H])[H]
[H]N([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)OC([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C(=O)C([H])([H])SC([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC1=C(C2=NC3=C(N2[H])C([H])=C([H])C([H])=C3[H])C(=O)N(C2=C([H])C([H])=C([H])C([H])=C12)C([H])([H])[H]
[H]C1=C([H])C2=C(C([H])=C1[H])C([H])([H])[C@]([H])(N2C(=O)C([H])([H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2F)C([H])([H])C1([H])[H])C([H])([H])[H]
[H]C1=C([H])C(=C([H])O1)[C@@]1([H])OC(=O)[C@]2([H])C([H])([H])C([H])([H])[C@@]3(C([H])([H])[H])[C@]([H])(C(=O)OC([H])([H])[H])C([H])([H])[C@]([H])(OC(=O)C4=C([H])C([H])=C([H])C([H])=C4[H])C(=O)[C@]3([H])[C@@]2(C([H])([H])[H])C1([H])[H]
[H]C1=C([H])C([H])=C(C(=C1[H])C1=NC(=NC(=N1)N(C1=C(Br)C([H])=C(C([H])=C1[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])[H])C([H])([H])[H])C(F)(F)F
[H]N(C(=O)OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=NOC(=N1)C1=NN([H])C2=C([H])C([H])=C([H])C([H])=C12
[H]C1=NC([H])=C2N1C([H])([H])C1=C([H])C([H])=C(C#N)C(OC3=C([H])C([H])=C(C(=C3[H])C([H])([H])N3C(=O)C([H])([H])[N@@](C([H])([H])C3([H])[H])C2([H])[H])C([H])([H])C([H])([H])[H])=C1[H]
[H]N(N([H])C(=O)C([H])([H])C1=C([H])C([H])=C([H])S1)C(=S)N([H])C(=O)C(\[H])=C(/[H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]C1=C([H])N=C(C(OC2([H])C([H])([H])C([H])([H])N(C3=NC([H])=C([H])C([H])=C3[H])C([H])([H])C2([H])[H])=N1)C1([H])C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]OC(=O)C([H])([H])[C@]([H])(N([H])C(=O)C([H])([H])N([H])C(=O)C1=C([H])C(N([H])C2=NC([H])([H])[C@@]([H])(O[H])C([H])([H])N2[H])=C([H])C(O[H])=C1[H])C1=C([H])C(Cl)=C([H])C(=C1O[H])C([H])([H])[H]
[H]N([H])C(=O)C([H])([H])N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]1([H])N(C(=O)[C@@]2([H])N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])[H])C([H])([H])SSC2([H])[H])C([H])([H])C2=C([H])C([H])=C([H])O2)[C@@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C(=O)N([H])[H])C([H])([H])C(=O)N([H])[H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C([H])([H])C([H])([H])N([H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]OC1=C(N([H])S(=O)(=O)C([H])([H])[H])C([H])=C(C([H])=C1[H])[C@]([H])(O[H])C([H])([H])N([H])[C@@]([H])(C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
COC(=O)C1=CC(NC(=O)N(CCC(C2=CC=CC=C2)C2=CC=CC=C2)CC2=CC=CC=C2)=CC=C1
[H]OC(=O)C([H])([H])[C@@]([H])(N([H])C(=O)C1=C(N([H])C(=O)OC([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C(=C([H])C(=C1[H])C([H])([H])[H])C([H])([H])[H])C(=O)C([H])([H])F
[H]OC(C#CC1=NC(=C([H])C2=C1N=C(N2C([H])([H])C([H])([H])[H])C1=NON=C1N([H])[H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]OC(=O)C1=C(N=C(N1C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C(C([H])=C([H])C([H])=C1[H])C(=O)O[H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)N1C([H])([H])C([H])([H])C([H])(C2=NC(=NO2)C([H])([H])[H])C([H])([H])C1([H])[H])[C@]1([H])C([H])([H])[C@@]1([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC(=O)[C@]([H])(N([H])S(=O)(=O)C1=C([H])C([H])=C(OC([H])([H])C#CC([H])([H])[H])C([H])=C1[H])C([H])([H])C1=C([H])N(C2=C1C([H])=C([H])C([H])=C2[H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H]
[H]N(C(=O)N([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C1=C(OC([H])([H])C([H])([H])C([H])([H])N2C([H])=NC(=C2[H])C2=C([H])C([H])=C([H])C([H])=C2[N+]([O-])=O)C([H])=C([H])C([H])=C1C([H])([H])[H]
[H]OC1=NC2=C([H])C([H])=C([H])C([H])=C2N1[C@]1([H])C([H])([H])C([H])([H])N2[C@]([H])(C([H])([H])C([H])([H])C([H])([H])[C@@]2([H])C2([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C1([H])[H]
[H]C1=C([H])C2=C([H])C([H])=C(C([H])=C2C([H])=C1[H])S(=O)(=O)N(C1=C([H])C([H])=C(C([H])=C1[H])N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N=C(N([H])[H])C1=C([H])C([H])=C([H])C(=C1[H])C([H])([H])[C@]([H])(N([H])S(=O)(=O)C1=C(C([H])=C(C([H])=C1C([H])(C([H])([H])[H])C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])C(=O)N1C([H])([H])C([H])([H])N(C(=O)OC([H])([H])C([H])([H])[H])C([H])([H])C1([H])[H]
NC1=NC(N)=C2N=C(CNC3=CC=C(C=C3)S(N)(=O)=O)C=NC2=N1
[H]OC(=O)C1=C([H])C(=C([H])C2=C([H])C([H])=C([H])C([H])=C12)N1C(=C([H])C([H])=C1C([H])([H])[H])C1=C([H])C(Br)=C([H])C([H])=C1OC([H])([H])C1=C([H])C([H])=C(F)C([H])=C1F
[H]C([H])=C([H])C([H])([H])SC1=NC2=C(N=N1)C1=C(C([H])=C([H])C([H])=C1[H])N(C(=O)C([H])([H])[H])[C@@]([H])(O2)C1=C([H])N=C([H])C([H])=C1[H]
[H]OC1=C(N([H])S(=O)(=O)C2=C([H])C(=C([H])C([H])=C2C([H])([H])[H])C([H])([H])[H])C([H])=C([H])C(=C1C([H])([H])C(=O)N([H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C(=N[H])N([H])[H])C([H])([H])[H]
[H]OC1=C([H])C([H])=C2N([H])C([H])=C(C2=C1[H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]OC(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]1([H])N(C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])[H])[C@@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])[H])C([H])([H])C(=O)N([H])[H])C([H])([H])C([H])([H])C1([H])[H])[C@@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(O[H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=N[H])N([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=N[H])N([H])[H])C([H])([H])C1=C([H])C([H])=C(O[H])C([H])=C1[H]
[H]S\C(=N\C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H])N([H])C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)N([H])[H]
[H]N(C(=O)C1=C([H])[N+]([O-])=C(C([H])=C1[H])S(=O)(=O)C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C(F)C([H])=C1[H]
CN1C=C(C(=O)N(C)C1=O)C1=CC=C(C[C@H](NC(=O)C2=C(Cl)C=CC=C2Cl)C(O)=O)C=C1C
[H]N([H])C1=C([H])C([H])=C(C([H])=C1N([H])C(=O)C1=C([H])C([H])=C([H])N=C1[H])N1C([H])=NC([H])=C1[H]
CN1CCN(CCNC(=O)C2=CC=C(C=C2)C(=O)NO)CC1
[H]N(C(=O)OC1=C([H])C(=C([H])C([H])=C1[H])C(=O)C1=NC2=C([H])C([H])=C([H])C([H])=C2S1)C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]N(C(=O)N1C(=O)N(C2=C([H])C([H])=C([H])C([H])=C12)C1([H])C([H])([H])C1([H])[H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N(\C(=N\S(=O)(=O)C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C(OC([H])([H])[H])=NC([H])=N1
[H]OC(=O)C([H])([H])[C@@]1(C2=C([H])C([H])=C(F)C([H])=C2[H])[C@@]2([H])C([H])([H])[C@@]3([H])C([H])([H])[C@]1([H])C([H])([H])[C@](O[H])(C3([H])[H])C2([H])[H]
[H]OC1=C([H])C(=C(C(=C1[H])C([H])([H])[H])C([H])([H])[C@]([H])(N([H])[H])C(=O)N1C([H])([H])C2=C(C([H])=C([H])C([H])=C2[H])C([H])([H])[C@@]1([H])C(=O)N([H])[C@]([H])(C(=O)C1=NC2=C([H])C([H])=C([H])C([H])=C2N1[H])C([H])([H])C(=O)N([H])[H])C([H])([H])[H]
[H]C1=C([H])C(=C([H])C([H])=C1C([H])([H])[H])S(=O)(=O)C1=C([H])C([H])=C(C([H])=C1[H])[C@]([H])(N1C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])[H]
[H]OC(=O)C([H])([H])C([H])([H])C([H])([H])C(\[H])=C(\[H])C([H])([H])[C@@]1([H])[C@]([H])(N([H])S(=O)(=O)C2=C([H])C([H])=C3OC4=C(C([H])=C([H])C(=C4[H])[N+]([O-])=O)C3=C2[H])[C@]2([H])C([H])([H])C([H])([H])[C@@]1([H])C2([H])[H]
[H]OC([H])([H])[C@@]1([H])O[C@]([H])(O[P@](=O)(O[H])O[P@](=O)(O[H])O[P@](=O)(O[H])O[P@](=O)(O[H])OC([H])([H])[C@@]2([H])O[C@@]([H])(N3C([H])=C([H])C(=O)N([H])C3=O)[C@]([H])(O[H])[C@]2([H])O[H])[C@]([H])(N([H])C(=O)C([H])([H])[H])[C@@]([H])(O[H])[C@]1([H])O[H]
[H]N1C(=O)N(C([H])([H])C1(C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C([H])C(Cl)=C2[H])C([H])([H])C1([H])[H]
[H]O[C@]1([H])C([H])([H])N(C([H])([H])C([H])([H])[C@]11C(=O)N(C2=C([H])C([H])=C(OC(F)(F)F)C([H])=C2[H])C([H])([H])C1([H])[H])S(=O)(=O)C1=C([H])C([H])=C([H])N=C1Cl
[H]N(C(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C1=C(C(=C([H])C([H])=C1[H])N1N=C(N(C1=O)C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1S(=O)(=O)N([H])C(=O)C1=C([H])C([H])=C([H])C([H])=C1Cl)C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)C([H])([H])[H])C1=NC2=C(OC3=NC([H])=NC(=C3[H])C3=C(N([H])C(=O)[C@@]4([H])N([H])C([H])([H])C([H])([H])C4([H])[H])C([H])=C(C([H])=C3[H])C(F)(F)F)C([H])=C([H])C([H])=C2S1
[H]OC1=C([H])C([H])=C([H])C(=C1[H])C1=C2N=C([H])C([H])=C(N2N=C1C1=C([H])C([H])=NC([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])N1C([H])([H])[C@@]2([H])N([H])C([H])([H])[C@]1([H])C2([H])[H]
[H]OC1=C([H])C([H])=C(C([H])=C1OC([H])([H])[H])C([H])([H])C(=O)OC([H])([H])C1=C([H])[C@@]2([H])[C@@]3([H])[C@@](OC(=O)C([H])([H])C4=C([H])C([H])=C([H])C([H])=C4[H])(C([H])([H])[C@@]([H])(C([H])([H])[H])[C@]2(O[H])[C@]2([H])C([H])=C(C(=O)[C@@]2(OC([H])([H])[H])C1([H])[H])C([H])([H])[H])C3(C([H])([H])[H])C([H])([H])[H]
[H]OC1=C(Cl)C([H])=C([H])C(OC([H])([H])[H])=C1C(=O)N([H])C([H])([H])[C@@]1([H])N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(C(=O)[C@]1([H])N(C([H])([H])C([H])([H])C1([H])[H])S(=O)(=O)C1=C([H])C([H])=C(Cl)C([H])=C1[H])[C@@]([H])(C([H])=O)C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)C1=C([H])C2=C3OC([H])([H])C([H])([H])C([H])([H])C3=C(N=C2C([H])=C1[H])C1=C([H])C([H])=C(Cl)C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])C1=C2C(=NC3=C1C([H])=C([H])C(Cl)=C3[H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H]
[H]C1=C([H])N=C(S1)C1=C([H])C(=C([H])C([H])=C1[H])[C@]1([H])C([H])([H])[C@]2([H])O[C@@]([H])(C([H])([H])C2([H])[H])[C@]1([H])C(=O)OC([H])([H])[H]
[H]N([H])C1=C([H])N=C(N(C1=O)C([H])([H])C(=O)N([H])[C@@]([H])(C(=O)C(F)(F)C(=O)N([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC(=O)[C@@]([H])(N([H])S(=O)(=O)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(OC([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])=C1[H]
[H]N(C(=O)N(C([H])([H])[H])C1([H])C([H])([H])C([H])([H])N(C(=O)C([H])([H])[H])C([H])([H])C1([H])[H])C1([H])C([H])([H])C([H])([H])N(C2=C([H])C(F)=C([H])C(F)=C2[H])C([H])([H])C1([H])[H]
[H]OC(=O)C([H])([H])C([H])([H])C1=C(N([H])C2=C1C(=O)C([H])([H])C([H])([H])C2([H])[H])C(\[H])=C1/C(=O)N([H])C2=C([H])C([H])=C(C([H])=C12)S(=O)(=O)N([H])C([H])([H])[H]
[H]C1=NN(C([H])=C1C([H])([H])C1=C([H])N(C(SC([H])([H])C2=C([H])C([H])=C(F)C([H])=C2[H])=NC1=O)C([H])([H])C(=O)N(C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)C([H])([H])[H])C([H])([H])[H]
[H]N1N=C(C2=C3C([H])=C([H])C([H])=C([H])C3=C([H])C3=C([H])C([H])=C([H])C([H])=C23)C([H])([H])[C@@]1([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N([H])C1=C(Cl)C([H])=C([H])C(=C1[H])C1=NO[C@@](C(=O)N([H])C2=C([H])C([H])=C(C([H])=N2)C2=C([H])C([H])=C([H])C([H])=C2S(=O)(=O)N([H])[H])(C([H])([H])N([H])S(=O)(=O)C2=C([H])C([H])=C([H])N=C2[H])C1([H])[H]
[H]O[C@]1([H])C2=C([H])C(OC([H])([H])C3=NC4=C([H])C([H])=C([H])C([H])=C4C([H])=C3[H])=C([H])C([H])=C2C([H])([H])C([H])([H])[C@@]1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C(Cl)C([H])=C1Cl)C([H])([H])C1(C2=C([H])C([H])=C([H])C([H])=N2)C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])S(=O)(=O)C([H])([H])C([H])([H])[H]
[H]N(C1=C(Cl)C(=NO1)C([H])([H])[H])S(=O)(=O)C1=C(C([H])=C([H])S1)C(=O)C([H])([H])C1=C(C([H])=C2OC([H])([H])OC2=C1[H])C([H])([H])[H]
[H]ON([H])C(=O)C([H])([H])OC1=C([H])C([H])=C2C(=C1[H])C([H])([H])N([H])[C@]([H])(C(=O)N([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C2([H])[H]
[H]OC1=C2C(N([H])C([H])=C2C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H])=C([H])C([H])=C1[H]
[H]N(C(=O)C1=C([H])C([H])=C(C([H])=C1[H])N(C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[H])C1=C([H])C2=C([H])C([H])=C([H])C([H])=C2N=C1[H]
[H]N([H])C(=O)N1C2=C(OC([H])([H])C1([H])[H])C([H])=C(OC1=C([H])C([H])=NC3=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C([H])=C13)C([H])=C2[H]
[H]N(C1=C([H])C([H])=NC(=N1)N1C([H])([H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])C1([H])[H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C1=NC([H])=C(C([H])=C1[H])C(=O)OC1=C([H])C([H])=C(OC([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])=C1[H]
[H]OC([H])([H])C(C(=O)N([H])C1=C([H])C([H])=C2N(C([H])=C(C2=C1[H])C([H])([H])C1=NC(=C([H])C([H])=C1[H])C1=C([H])C([H])=C(F)C([H])=C1OC([H])([H])[H])C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])[C@]2([H])C([H])([H])[C@@]1([H])[C@@]1([H])C(=O)N(OC([H])([H])C([H])([H])N3C([H])([H])C([H])([H])N(C4=C([H])C(=C([H])C([H])=C4[H])C(F)(F)F)C([H])([H])C3([H])[H])C(=O)[C@@]21[H]
[H]N1C(=NC2=C1N([H])C(=O)N(C2=O)C([H])([H])C([H])([H])C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C1=C(C#N)C([H])=NC2=C([H])C(=C([H])C([H])=C12)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])[C@]1([H])C([H])([H])[C@@]1([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=S)N([H])C([H])([H])C1=C([H])C([H])=C(F)C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]O[C@@]1([H])C([H])([H])C([H])([H])[C@@]2(C([H])([H])[H])[C@@]([H])(C([H])([H])C([H])([H])[C@@]3([H])[C@@]4([H])C([H])([H])C([H])([H])C(=O)N(C([H])([H])[H])[C@@]4(C([H])([H])[H])C([H])([H])C([H])([H])[C@]23[H])C1([H])[H]
[H]OC(=O)C1=C([H])C([H])=C([H])C([H])=C1C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1C(=NC([H])=C1C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])O[H]
[H]N(C1=NN([H])C2=C1C([H])=NC(OC1=C(F)C([H])=C(F)C([H])=C1[H])=N2)C([H])(C([H])([H])[H])C([H])([H])[H]
[H]C1=NC2=C(C([H])=C1[H])C(=O)N(C1=C([H])C([H])=C(C#N)C([H])=C1[H])C(=N2)[C@]([H])(N(C(=O)C([H])([H])C1=C([H])C(=C(F)C([H])=C1[H])C(F)(F)F)C([H])([H])C([H])([H])S(=O)(=O)C([H])([H])C([H])([H])[H])C([H])([H])[H]
[H]N([H])[C@@]1([H])C([H])([H])C2=C(OC([H])([H])[H])C([H])=C([H])C(OC([H])([H])[H])=C2C([H])([H])C1([H])[H]
[H]C1=C([H])C(OC([H])([H])C([H])([H])C([H])([H])OC([H])([H])C([H])([H])C([H])([H])N2C([H])([H])C([H])([H])C([H])([H])[C@]([H])(C([H])([H])[H])C2([H])[H])=C([H])C([H])=C1Cl
O=C1C=C(OC2=C1SC=C2C1=CC=CC=C1)N1CCOCC1
[H]N(C(=O)N([H])C1=C([H])C2=C(O\C(=C(\[H])C3=C([H])N(C4=NC([H])=C([H])C(N5C([H])([H])C([H])([H])C([H])(C(=O)N(C([H])([H])[H])C([H])([H])C6=C([H])C([H])=NC([H])=C6[H])C([H])([H])C5([H])[H])=C34)C([H])([H])[H])C2=O)C([H])=C1[H])C1=C([H])N=C([H])C([H])=C1[H]
[H]N(C(=O)C([H])([H])[H])C1=NC(=C(N1[H])C1=C([H])N2N=C([H])N=C2C([H])=C1[H])C1=NC(=C(F)C([H])=C1[H])C([H])([H])[H]
[H]OC([H])([H])C1=C([H])C([H])=C2C(=C1[H])N(C(=C2C(=O)N([H])C([H])([H])C1=C([H])C(F)=C(F)C([H])=C1[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C1=C([H])C2=C(C([H])=C1[H])C1=C3N2C(=O)C([H])=C2C3=[N+](C([H])=C1[H])C([H])([H])C([H])([H])C2([H])[H]
[H]N1C([H])=C([H])C2=C(C([H])=C([H])C(OC3([H])C([H])([H])C([H])([H])N([H])C([H])([H])C3([H])[H])=C2[H])C1=O
[H]OC1=C([H])C([H])=C(C([H])=C1[H])[C@@]1([H])N(N=C(C2=C([H])C([H])=C([H])C([H])=C2O[H])C1([H])[H])C(=O)C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N=C(N([H])[H])N([H])C([H])([H])C([H])([H])C([H])([H])[C@@]([H])(N([H])C(=O)[C@]1([H])N(C(=O)C(=O)C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C1([H])[H])C([H])=O
[H]N([C@@]([H])(C1=NC2=C(N1[H])C([H])=C([H])C(=C2[H])C(F)(F)F)C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])[C@]1([H])C([H])([H])C(=O)N([H])S1(=O)=O)S(=O)(=O)C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
COC1=CC(Br)=C(C=C1OC)S(=O)(=O)NC1=CC=C(C(OC[C@@H]2CCCN2C)=C1)C(F)(F)F
[H]O[C@]1(C([H])([H])C([H])([H])N([H])C(=O)C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C([H])([H])[H])C([H])([H])[C@@]2([H])C([H])([H])C([H])([H])[C@]1(C([H])([H])S(=O)(=O)N1C([H])([H])C([H])([H])C3(C([H])=C([H])C4=C([H])C([H])=C([H])C([H])=C34)C([H])([H])C1([H])[H])C2(C([H])([H])[H])C([H])([H])[H]
[H]C([H])=C([H])C([H])([H])N(C([H])([H])C1=C(N=C2N1C1=C(N=C([H])C([H])=C1[H])N2C1=C(C([H])=C(C([H])=C1C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]N(C(=O)C1=NC([H])=C([H])C([H])=C1[H])C1=C([H])C2=C(C([H])=C1[H])N(C([H])=C2[H])C(=O)C1=C([H])C([H])=C(F)C([H])=C1Cl
[H]N(N1C2=C([H])C([H])=C(Cl)C([H])=C2SC2=C1C([H])=C([H])C([H])=C2[H])C(=O)C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H]
[H]N([H])[C@@]1([H])C([H])([H])C([H])([H])[C@]([H])(N([H])C2=NC3=C(C#N)C([H])=NN3C(N([H])C3=C([H])C(Cl)=C(F)C([H])=C3[H])=C2[H])C([H])([H])C1([H])[H]
[H]N([H])C(=O)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C(=O)N(C([H])([H])C([H])=C([H])[H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C2(C3=C([H])C(F)=C([H])C([H])=C3[H])C([H])([H])C([H])([H])N(C(=O)C3=C([H])C(=C(F)C([H])=C3Cl)S(=O)(=O)N([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]O[C@@]1([H])[C@@]2([H])O[C@]([H])(C([H])([H])OC([H])([H])C([H])([H])OC3=C([H])C(Cl)=C(C([H])=C23)C([H])([H])C2=C([H])C([H])=C(OC([H])([H])C([H])([H])[H])C([H])=C2[H])[C@@]([H])(O[H])[C@]1([H])O[H]
[H]N(C(=O)C([H])([H])N1C([H])([H])C([H])([H])N(C2=C([H])C([H])=C(C([H])=C2[H])C(=O)OC([H])([H])C([H])([H])[H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC2=C([H])C(C#N)=C([H])C(=C2O1)C([H])([H])[H]
[H]C1=C(C([H])([H])[H])C([H])([H])N(O1)C1([H])C([H])([H])C([H])([H])N(C(=O)N2OC(=O)C(=C2C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]ON([H])C(=O)[C@@](O[H])(C([H])([H])[H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])[H])C([H])([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C1=C(I)C(Cl)=C([H])C(=C1[H])N1C(=O)[C@@]2([H])[C@@]3([H])O[C@]([H])(C([H])([H])C3([H])[H])[C@@]2([H])C1=O
[H]C1=NC([H])=C(C([H])=C1[H])C1=C([H])C2=C([H])C([H])=C([H])C([H])=C2[C@@]([H])(C([H])([H])C([H])([H])[H])C1([H])[H]
[H]O[C@@]1([H])OC(=O)C(=C1C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC(=O)C([H])([H])C([H])([H])[C@]([H])(N([H])C(=O)C1=NC(=C([H])C(=C1[H])N(C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C(=O)N1C([H])([H])C([H])([H])N(C(=O)OC([H])([H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]ON([H])C(=O)[C@]1([H])N(C([H])([H])C2=C([H])C(N([H])[H])=C([H])C([H])=C2C1([H])[H])[P@](=O)(OC([H])([H])C([H])([H])[H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]\C(=C(\C1=C([H])C([H])=C([H])N=C1[H])C1=C([H])C(Cl)=C([H])C([H])=C1[H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H]
[H]OC(=O)C1=C([H])C([H])=C(C(F)=C1[H])C1=NC2=C(C([H])=C([H])C(C#N)=C2[H])N(C2=C1C([H])=C1C(=C2[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C([H])([H])C1(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])[H]
[H]N(C(=O)N([H])C1=C([H])C([H])=C([H])C2=C1OC(=C2[H])C1=C(C([H])=C([H])C([H])=C1[H])C([H])(C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])C([H])=C(OC2=C(C([H])=NC(F)=C2[H])N(C(=O)C([H])([H])[H])C([H])([H])C2=C(OC([H])([H])[H])C([H])=C([H])C([H])=C2[H])C([H])=C1[H]
[H]C1=C([H])C2=NC(=C([H])C([H])=C2C(OC([H])([H])C([H])([H])N2C([H])([H])C([H])([H])C([H])(C([H])([H])C3=C([H])C([H])=C([H])C(=C3[H])N3C([H])([H])C([H])([H])C([H])([H])C([H])([H])C3([H])[H])C([H])([H])C2([H])[H])=C1[H])C([H])([H])[H]
CC1=CC=C(CNC(=O)C2=NN=C(C=C2)N2CCN(CC2)C(=O)C2=CC=CC=C2C(F)(F)F)O1
[H]C1=C([H])C([H])=C(SC([H])([H])C2=C(N3C(=O)[C@]([H])(OC([H])([H])[H])[C@@]3([H])S(=O)(=O)C2([H])[H])C(=O)OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])=C1[H]
[H]N(C(=O)P(=O)(OC([H])([H])C([H])([H])[H])OC([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=O)P(=O)(OC([H])([H])C([H])([H])[H])OC([H])([H])C([H])([H])[H]
[H]ON([H])C(=O)C([H])([H])[C@]([H])(C1=NC(=NO1)C1=C([H])C([H])=C([H])C(=C1[H])C(=O)OC([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N([H])C(=O)C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C2=C([H])C([H])=C(C(F)=C2N1[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]OC(=O)C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C2=C(C([H])=C1[H])C([H])([H])C([H])([H])[C@]([H])(N([H])C([H])([H])[C@]([H])(O[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H])C2([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C([H])C([H])=C1C1=C([H])C([H])=C(C([H])=C1[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C1=NC2=C([H])C([H])=C(C([H])=C2C([H])=C1[H])C(=O)N([H])[C@]([H])(C(=O)N([H])C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N1C(=O)[C@@]2([H])C([H])([H])SC([H])([H])C([H])([H])[C@]2([H])N=C1C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])=C(C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]OC1=C([H])C([H])=C(C([H])=C1[H])[C@]1([H])C([H])([H])N([H])C2=C([H])C(O[H])=C([H])C([H])=C2C1([H])[H]
[H]N(C1=NC2=C([H])C([H])=C(Cl)C([H])=C2C2=NC(=NN12)C1=C([H])C([H])=C([H])O1)C([H])(C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])C2=C(C([H])=C1[H])[C@@]1(C([H])([H])[S@]2=O)C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])[C@@]([H])(C2=C([H])C([H])=C(Cl)C(Cl)=C2[H])C([H])([H])N(C([H])([H])[H])S(=O)(=O)C2=C([H])C([H])=C([H])C(Cl)=C2[H])C([H])([H])C1([H])[H]
[H]ON1C(C2=C(C([H])=C(N([H])[C@@]3([H])N([H])C([H])=NC4=C3N=C([H])N4[C@]3([H])O[C@]([H])(C([H])([H])O[H])[C@@]([H])(O[H])[C@@]3([H])O[H])C([H])=C2[H])C1(C([H])([H])[H])C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]C1=NC(OC([H])([H])C([H])([H])OC([H])([H])[H])=C([H])C(=C1[H])S(=O)(=O)C1=C([H])C2=C(C([H])=C1[H])N(C(=N2)C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]O[C@@]([H])(C([H])([H])[C@@]([H])(OC([H])([H])[H])C(=O)N([H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])[C@@]([H])(N([H])C(=O)C1=C([H])C(=C([H])C(=C1[H])C(=O)N([H])[C@@]([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H])N(C([H])([H])[H])C([H])([H])S(=O)(=O)C([H])([H])[H])C([H])([H])OC1=C([H])C(F)=C([H])C(F)=C1[H]
[H]N([C@@]1([H])C([H])([H])C([H])([H])[C@@]([H])(C([H])([H])C1([H])[H])[C@]([H])(C([H])([H])[H])[C@@]([H])(C(=O)N1C([H])([H])C([H])([H])[C@]([H])(F)C1([H])[H])[N+]([H])([H])[H])S(=O)(=O)C1=C([H])C([H])=C(OC(F)(F)F)C([H])=C1[H]
[H]OC(=O)[C@@]1([H])C([H])([H])N(C([H])([H])C([H])([H])OC([H])([H])C([H])=C(C2=C(C([H])=C([H])C([H])=C2[H])C([H])([H])[H])C2=C(C([H])=C([H])C([H])=C2[H])C([H])([H])[H])C([H])([H])C([H])([H])C1([H])[H]
[H]N1C(=NC2=C(C([H])=C(C([H])=C12)C(F)(F)F)C1=C([H])C(F)=C(F)C(F)=C1[H])N1C([H])([H])C([H])([H])N(C2=C(Cl)C([H])=C(Br)C([H])=N2)C([H])([H])[C@@]1([H])C([H])([H])[H]
[H]N([H])C1=NC2=C(C([H])=C(S2)C(=O)N([H])C([H])([H])C([H])([H])[H])C(=N1)C1=C([H])C([H])=C(C([H])=C1C([H])([H])[H])C([H])([H])[H]
[H]OC(=O)C1=C([H])C(Cl)=C(C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])N1C(=O)N(C2=C([H])C(OC([H])([H])[H])=NC([H])=N2)C2(C1=O)C([H])([H])C([H])([H])N(C([H])([H])C1=C(C([H])=C([H])C([H])=N1)C([H])([H])[H])C([H])([H])C2([H])[H]
[H]N(N(C([H])([H])[H])C([H])([H])[H])C(=O)C1=C([H])C([H])=C(N([H])C(=O)N([H])C2=C([H])C([H])=C(C([H])=C2[H])C2=NC3=C(C([H])=NN3C([H])([H])C([H])([H])[H])C(=N2)N2C([H])([H])[C@@]3([H])O[C@]([H])(C([H])([H])C3([H])[H])C2([H])[H])C([H])=C1[H]
[H]N([H])C1=C2C(=C([H])C([H])=C1[H])C(=O)N([H])C([H])([H])C2([H])[H]
[H]N(C1=C([H])C([H])=C2N([H])N=C(C3=C([H])C4=C(N3[H])C([H])=C(C([H])=C4[H])C([H])([H])[H])C2=C1[H])S(=O)(=O)C1=C(N(C([H])=N1)C([H])([H])[H])C([H])([H])[H]
[H]N([H])C1=C([H])C([H])=C([H])C(OC([H])([H])C([H])([H])C([H])([H])N([H])C([H])([H])[C@]2([H])OC3=C(C([H])=C([H])C([H])=C3[H])C([H])([H])C2([H])[H])=C1[H]
[H]\C(C1=C([H])N=C([H])C([H])=C1[H])=C1\C([H])([H])N2[C@]3([H])C([H])([H])C([H])([H])[C@@]2([H])[C@]([H])(C(=O)OC([H])([H])[H])[C@@]1([H])C3([H])[H]
[H]OC1=C2C(OC(C([H])([H])[H])(C([H])([H])[H])[C@]3([H])C([H])([H])C([H])([H])C(=C([H])[C@@]23[H])C([H])([H])[H])=C([H])C(=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])I
[H]N1C(=NC(=C1C1=C([H])C2=C(C([H])=C1[H])N(C(=O)N2C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C([H])C(=C1[H])C([H])([H])[H])C1=C([H])C([H])=C([H])S1
[H]N(\N=C(/[H])C1=C([H])C([H])=NC([H])=C1[H])C1=C2C([H])=NN(C2=NC([H])=N1)C1=C([H])C([H])=C([H])C(Br)=C1[H]
[H]N(C(=O)N1C(=O)[C@@]([H])(OC(=O)N([H])[C@]([H])(C(=O)C(=O)N([H])[C@@]([H])(C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C(C([H])([H])[H])(C([H])([H])[H])C1([H])[H])C1=C(ON=C1C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C(C(=C1[H])N1C([H])=NC2=C(C([H])=C(C([H])=C2[H])N2C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C2([H])[H])C1=O)C([H])([H])[H])C([H])([H])C([H])([H])[H]
[H]N(C(=O)C1=C([H])C(N([H])C2=C3C([H])=NN(C3=NC([H])=N2)C2=C(Cl)C([H])=C([H])C([H])=C2Cl)=C(C([H])=C1[H])C([H])([H])[H])C([H])([H])[H]
[H]N([H])C(=O)C1=C2C(=O)N(C([H])([H])C3([H])C([H])([H])C([H])([H])N([H])C([H])([H])C3([H])[H])C([H])([H])C2=C([H])C([H])=C1[H]
[H]N(C(=O)C(\[H])=C(/[H])C([H])=C(C1=C([H])C([H])=C([H])C(OC([H])([H])[H])=C1[H])C1=C([H])C([H])=C([H])C(OC([H])([H])[H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1=C([H])N=C([H])C([H])=C1[H]
[H]C1=NC([H])=C(OC([H])([H])C([H])([H])[H])C([H])=C1C1=C([H])C2=C([H])C([H])=C(OC([H])([H])[H])C([H])=C2C([H])=C1[H]
[H]C1=C([H])C2=C([H])C([H])=C(C([H])=C2C([H])=C1[H])C([H])([H])C(=O)N(C([H])([H])[H])[C@]1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@]1([H])N1C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
COC1=CC=C(F)C=C1C(C)(C)CC(O)(CC1=CC2=CC=NC=C2N1)C(F)(F)F
[H]\C(=C(\[H])C1=C([H])C([H])=C(SC2=C(OC3([H])C([H])([H])C([H])([H])SC([H])([H])C3([H])[H])C([H])=C([H])C([H])=C2[H])C(=C1C(F)(F)F)C(F)(F)F)C(=O)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]O[C@@]1([H])C([H])=C2C([H])([H])C([H])([H])N(C([H])([H])[H])[C@@]2([H])[C@@]2(OC(=O)C3=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C([H])=C23)[C@]1([H])O[H]
[H]N1C([H])([H])C(C(=O)OC([H])([H])C([H])([H])[H])=C(C2=C([H])C([H])=C(Cl)C(Cl)=C2[H])C([H])([H])C1([H])[H]
[H]OC(=O)C([H])([H])C([H])([H])C([H])([H])C(\[H])=C(\[H])C([H])([H])[C@@]1([H])[C@]([H])(N([H])S(=O)(=O)C2=C([H])C([H])=C(C([H])=C2[H])C2=NN=NN2C2=C([H])C([H])=C([H])C([H])=C2[H])[C@]2([H])C([H])([H])C([H])([H])[C@@]1([H])C2([H])[H]
[H]N(C(=O)C([H])([H])[H])C1=C([H])C(=C([H])C([H])=N1)C1=C(N=C(SC([H])([H])[H])N1C([H])([H])C([H])([H])N([H])C(=O)C([H])([H])[H])C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]O[C@]1(C([H])([H])[H])C([H])([H])[C@]([H])(C2=NC(=C3N2N=C([H])N=C3N([H])[H])C2=C([H])C3=C(C([H])=C([H])C(=N3)C3=C([H])C([H])=C([H])C([H])=C3[H])C([H])=C2[H])C1([H])[H]
[H]N1C([H])=C(C2=C1C([H])=C([H])C([H])=C2[H])C1=C(C(=O)C([H])([H])[H])C(=O)N([H])C1=O
[H]O[C@](C1=C([H])C2=C([H])C(=C(C([H])=C2N1[H])C(F)(F)F)[N+]([O-])=O)(C([H])([H])[H])C([H])([H])OC(=O)C1=C([H])C([H])=C(C([H])=C1[H])N(C([H])([H])[H])C([H])([H])[H]
[H]N([H])C(=O)C1=C([H])C([H])=C2C([H])=C(C([H])=C([H])C2=C1[H])C(=O)N([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C(=C([H])C([H])=C1[H])C(=O)OC([H])([H])[H]
[H]N(C(=O)C1=C([H])N(C2=NC(Cl)=C([H])C([H])=C2C1=O)C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1F)C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N1C([H])=C(C2=C1C([H])=C([H])C(C#N)=C2[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N(N([H])C(=O)C1=C([H])C([H])=C(C([H])=C1[H])C(F)(F)F)C(=O)C(=O)C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H]
[H]N1C(=O)C2(N(C3=C([H])C([H])=C([H])C([H])=C3[H])C1([H])[H])C([H])([H])C([H])([H])N(C([H])([H])C2([H])[H])[C@]1([H])C2=C([H])C([H])=C([H])C(=C2C([H])([H])C([H])([H])C1([H])[H])C([H])([H])[H]
CC1=C(CCOCCCO[N+]([O-])=O)C=C(N1C1=CC(F)=CC=C1)C1=CC=C(C=C1)S(C)(=O)=O
[H]C1=C([H])C(=C(C(=C1[H])C(F)(F)F)C([H])([H])[H])C([H])([H])N1C2=NC(=C([H])C(=O)N2N=C1C([H])([H])[H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]N1C(=NN=C1C1([H])C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C(C([H])=C2[H])C2=NC3=NC(=NC([H])=C3C([H])=C2C2=C([H])C([H])=C([H])C([H])=C2[H])N2C([H])([H])C([H])([H])N(C(=O)C([H])([H])[H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H])C1=NC([H])=C([H])C([H])=C1[H]
[H]N(C(=O)C([H])([H])[H])C([H])([H])C([H])([H])C1=C([H])C(=C([H])C([H])=N1)S(=O)(=O)C1=C([H])C2=C(C([H])=C1[H])N(C(=N2)C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]O[C@]([H])(C1=C([H])C([H])=C(S1)C1=NC([H])=C([H])C([H])=C1[H])[C@]1([H])N(C(=O)C([H])([H])[C@]1([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H]
CN(C)CCOC1=CC=C(C=C1)C1=C(C2=C(NC[C@@H]3CC[C@H]3O)N=CN=C2N1)C1=CC=CC=C1
CCCCCCNC1=C2C3=CC=C(SC4=CC=C(OC)C=C4)C4=CC=CC(C2=NC1=O)=C34
[H]O[C@]([H])(C1=C([H])N=C([H])C([H])=C1[H])C([H])([H])N([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C(C(=O)N([H])S(=O)(=O)C([H])([H])[H])C(N([H])C([H])(C([H])([H])[H])C([H])([H])[H])=C1[H]
[H]N(C(=O)C1=C(N([H])C(=O)C2=C([H])C([H])=C(C([H])=C2[H])N2C(=O)C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])=C([H])C(N([H])S(=O)(=O)C([H])([H])[H])=C1[H])C1=NC([H])=C(Cl)C([H])=C1[H]
[H]N(C(=O)N([H])C1=C([H])C([H])=C2C(N([H])C(=O)\C2=C(\[H])C2=C([H])C([H])=C([H])N2[H])=C1[H])C1=C([H])C([H])=C(OC2=C([H])C([H])=C([H])C([H])=C2[H])C([H])=C1[H]
[H]N(OC([H])([H])C([H])([H])[H])C(=O)C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)OC([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]O[C@@]1(C#C[H])C([H])([H])C([H])([H])[C@@]2([H])[C@]3([H])C([H])([H])C([H])([H])C4=C([H])C(=O)C([H])([H])C([H])([H])[C@]4([H])[C@@]3([H])C([H])([H])C([H])([H])[C@]12C([H])([H])[H]
[H]N(OC([H])([H])[H])C1=NC([H])=NC2=C([H])C([H])=C(C#CC([H])([H])N([H])C(=O)C3=C([H])N=C([H])N(C3=O)C([H])([H])C3=C([H])C([H])=C(F)C(F)=C3[H])C([H])=C12
[H]OC1=C2C(=O)C3=C(C(=O)C2=C([H])C([H])=C1[C@@]1([H])O[C@]([H])(C([H])([H])[H])[C@@]([H])(O[H])[C@]([H])(N(C([H])([H])[H])C([H])([H])[H])C1([H])[H])[C@@]1([H])OC(=O)C([H])([H])[C@@]1([H])O[C@]3([H])C([H])([H])[H]
[H]N([H])[C@@]([H])(C([H])([H])C(=O)N1C([H])([H])C2=C(C(=NN2[H])C2([H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H])C([H])([H])C1=C([H])C(F)=C([H])C([H])=C1F
[H]O[C@@]([H])(C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])[C@]([H])(O[H])[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(C([H])([H])C(=O)N(C([H])([H])[H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])SC([H])=N1)C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]C1=C([H])C(OC2=C([H])C(Cl)=C([H])C([H])=C2Cl)=C(C([H])=N1)C(=O)N1C2=C(C([H])=C([H])C([H])=C2[H])N(C([H])([H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]OC(=O)[C@@]([H])(N([H])C(=O)C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C(OC([H])([H])[H])C([H])=C([H])C([H])=C1OC([H])([H])[H]
[H]ON([H])C(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])OC1=C(OC([H])([H])[H])C([H])=C2N=C([H])N=C(N([H])C3=C([H])C(Cl)=C(OC([H])([H])C4=C([H])C(F)=C([H])C([H])=C4[H])C([H])=C3[H])C2=C1[H]
[H]C1=C([H])C2=C(C([H])=C1[H])C(=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N1C([H])([H])[C@@]2([H])C([H])([H])[C@]1([H])[C@@]([H])(C1=C([H])N=C(Cl)C([H])=C1[H])C2([H])[H]
[H]ON([H])C(=O)C1=C([H])C([H])=C(S1)C1=NN(C([H])=C1[H])C([H])([H])C([H])([H])N([H])C([H])([H])C1=C([H])C2=C(OC([H])=C2[H])C([H])=C1[H]
[H]OC(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])OC1=C([H])C([H])=C(N([H])C(=O)C2=C(O[H])C3=C([H])C([H])=C(C([H])=C3N=C2O[H])C(F)(F)F)C([H])=C1[H]
[H]N([C@]1([H])C([H])([H])C([H])([H])[C@](C(=O)N2C([H])([H])C([H])([H])N(C3=C([H])N=C([H])C(=N3)C(F)(F)F)C([H])([H])C2([H])[H])(C1([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])[C@@]1([H])C([H])([H])C([H])([H])OC([H])([H])[C@@]1([H])OC([H])([H])[H]
[H]N([H])[C@@]([H])(C([H])([H])C(=O)N1C([H])([H])C([H])([H])[C@@]([H])(N([H])C(=O)[C@@]1([H])C([H])([H])[H])C(F)(F)F)C([H])([H])C1=C(F)C([H])=C(F)C(F)=C1[H]