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C[C@H](NC(=O)C1=CNC2=NC=C(N=C12)C1CC1)C(C)(C)C
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[H]N(C(=O)N(C([H])([H])C1=C([H])SC([H])=C1[H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])[C@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])N([H])C(=O)C1=C(N=C(Cl)C([H])=C1C([H])([H])[H])C([H])([H])[H])C1=C([H])N=C([H])C([H])=C1[H]
[H]N(C1=NC2=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C([H])=C2N=C1[H])C1=C([H])C([H])=C([H])C(Cl)=C1[H]
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[H]N(C(=O)N([H])C([H])(C([H])([H])[H])C([H])([H])[H])C1=C(C([H])=C(C([H])=C1[H])C(F)(F)F)C(=O)N([H])C([H])([H])C(=O)N([H])[C@@]1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])N([H])C(=O)C1=C([H])C([H])=C(SC([H])([H])[H])C([H])=C1[H]
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C[Si](C)(C)CCOC(=O)CC1=C(NC2=C(Cl)C=CC=C2Cl)C=CC=C1
[H]N([H])C1=C(SC2=C([H])C([H])=C([H])C([H])=C2C([H])([H])N([H])C([H])([H])C([H])([H])F)C([H])=C([H])C(=C1[H])C([H])([H])[H]
[H]N(C1=NC(=NC2=C(N(N=C12)C([H])([H])[H])C1=C([H])C([H])=C(Cl)C([H])=C1Cl)C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]OC(=O)C([H])([H])N([H])[C@@]([H])(C(=O)N([H])C1(C(=O)N([H])C([H])([H])C2=C([H])N=C(C([H])=C2[H])C(=N[H])N([H])[H])C([H])([H])C1([H])[H])C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
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[H]OC(=O)C([H])([H])O\N=C(\C1=C([H])N(C(=O)N(C([H])([H])[H])C([H])([H])[H])C2=C1C([H])=C([H])C(=C2[H])C1=C([H])C([H])=C(F)C([H])=C1[H])C1=C2N(C([H])=C1[H])[C@]([H])(SC2([H])[H])C1=C([H])N=C([H])C([H])=C1[H]
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[H]N([H])C1=NOC2=C([H])C([H])=C(C([H])=C12)N1N=C(C([H])=C1C(=O)[C@@]([H])(C1=C([H])C([H])=C(C([H])=C1F)C1=C([H])C([H])=C([H])C([H])=C1S(=O)(=O)N([H])[H])C([H])([H])[H])C(F)(F)F
[H]OC(=O)C1=C([H])C([H])=C2N([H])C(=O)\C(=C(\[H])C3=C(C(=C([H])N3[H])C([H])([H])C([H])([H])C(=O)O[H])C([H])([H])[H])C2=C1[H]
[H]N([H])[C@]1([H])C([H])([H])N(C([H])([H])C2=C3N(N=C([H])N=C3N([H])C3=C([H])C4=C(C([H])=C3[H])N(N=C4[H])C([H])([H])C3=C([H])C(F)=C([H])C([H])=C3[H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]O[C@@]1([H])[C@@]([H])(O[C@]([H])(C(=O)N([H])C([H])([H])C([H])([H])[H])[C@@]1([H])O[H])N1C([H])=NC2=C(N=C([H])N=C12)N([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])S(=O)(=O)C1=C2C([H])=C([H])C([H])=C(N(C([H])([H])[H])C([H])([H])[H])C2=C([H])C([H])=C1[H]
[H]N([H])[C@@]1([H])C([H])([H])N(C2=NC([H])=C(N2C([H])([H])C#CC([H])([H])[H])C(=O)N(C([H])([H])[H])C([H])([H])C2=C3C([H])=C([H])C([H])=C([H])C3=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C1([H])[H]
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[H]ON([H])C(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=O)C(\[H])=C(\C(\[H])=C(/[H])C1=C([H])C([H])=C([H])C([H])=C1[H])/C([H])([H])[H]
[H]N(C(=O)C1=C([H])C(F)=C([H])C(F)=C1[H])[C@]([H])(C(=O)N([H])[C@]([H])(C(\[H])=C(/[H])S(=O)(=O)C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C(=C1[H])C([H])([H])[H]
[H]N(C(=O)C1([H])C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])S(=O)(=O)C1=C([H])C([H])=C(C([H])=C1[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N([H])C1(C(=O)N([H])C([H])([H])C2=C([H])C([H])=C([H])C(Cl)=C2[H])C([H])([H])C([H])([H])N(C2=NC([H])=NC3=C2C([H])=C([H])N3[H])C([H])([H])C1([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C2N([H])C(=O)\C(=C(\[H])C3=C(C([H])=C(N3[H])C([H])([H])[H])C([H])([H])[H])C2=C1[H]
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[H]OC(=O)[C@@]([H])(N([H])C(=O)C1=C([H])C([H])=C(N([H])C([H])([H])C2=NC([H])=C([H])N2[H])C([H])=C1C1=C([H])C([H])=C([H])C2=C([H])C([H])=C([H])C([H])=C12)C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H]
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[H]N(C(=O)C1=C(N(C(=N1)C([H])([H])C([H])([H])C([H])([H])[H])C1=C(OC([H])([H])[H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C([H])C([H])=C([H])C(=C2C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H]
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[H]N(C(=O)C([H])([H])C1=C([H])C(=C([H])C(=C1[H])C(F)(F)F)C(F)(F)F)C([H])([H])[C@]([H])(N1C([H])([H])C([H])([H])C([H])(N2C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C1=NC(OC([H])([H])[H])=NC(=C1[H])C1=C([H])N=C([H])O1)C([H])([H])C([H])([H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
BrC1=CC=C(C=C1)C1=NNC(NC(=O)CCCCN2CCCCC2)=C1
[H]C1=C([H])C(=NC(=C1[H])C([H])([H])[H])N1N=C([H])C(=C([H])C1=O)C1=C([H])C([H])=C(OC([H])([H])C([H])([H])C([H])([H])N2C([H])([H])C([H])([H])C([H])([H])[C@@]2([H])C([H])([H])[H])C([H])=C1[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N(C(=O)C1=C(C([H])([H])OC(=O)C([H])([H])[H])C([H])([H])S(=O)(=O)[C@@]2([H])N1C(=O)[C@]2([H])OC([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C(=O)C(=O)C2=C([H])C(OC([H])([H])[H])=C([H])C([H])=C12
[H]OC1=C([H])C2=C(C([H])=C1[H])C([H])([H])C1([H])N(C([H])([H])C3([H])C([H])([H])C3([H])[H])C([H])([H])C([H])([H])C22C([H])([H])C3(OC12C([H])([H])C3([H])[H])C([H])([H])N([H])C(=O)C1=C([H])C(O[H])=C([H])C([H])=C1[H]
[H]N(C(=O)C([H])([H])C([H])([H])[N+]1(C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C([H])C2=C1C(=O)C1=C([H])C([H])=C([H])C(N([H])C(=O)C([H])([H])C([H])([H])[N+]3(C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C3([H])[H])=C1C2=O
[H]N(C1=NC([H])=C([H])S1)C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])C(C([H])([H])[H])(C([H])([H])[H])C1([H])[H]
[H]OC1=C([H])C([H])=C(C([H])=C1[H])C(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C([H])C([H])=C([H])C([H])=C2OC([H])([H])[H])C([H])([H])C1([H])[H]
[H]N1C([H])=C(C(=O)N(C2=C([H])N=C(OC3=C(N=C([H])C([H])=C3[H])C([H])([H])[H])C([H])=C2[H])C([H])([H])[H])C2=C([H])C([H])=C([H])C([H])=C12
[H]OC([H])([H])[C@@]1([H])O[C@@]([H])(N2C([H])=NC3=C(N=C([H])N=C23)N([H])C2=C([H])C([H])=C(C([H])=C2[H])C([H])([H])C(=O)N([H])C2=C([H])C([H])=C(C([H])=C2[H])C([H])([H])C(=O)N([H])C([H])([H])C([H])([H])\N=C(/S[H])N([H])C2=C([H])C([H])=C(OC([H])([H])[H])C([H])=C2[H])[C@]([H])(O[H])[C@]1([H])O[H]
[H]N([H])C1=NC(=C([H])C(=C1[H])C([H])([H])[H])C([H])([H])[C@@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])OC([H])([H])[H]
[H]N1C2=C([H])C([H])=C([H])N=C2N(C(=O)C([H])([H])N2C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@]2([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C2=C(C([H])=C([H])C([H])=C2[H])C1=O
[H]N(C(=O)C1(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C1([H])[H])C1=C([H])C(=C(C([H])=N1)C([H])([H])[H])C([H])([H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]N(C(=O)[C@@]([H])(N([H])C(=O)OC([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])SSC1=C([H])C([H])=C([H])C([H])=N1)C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC([H])([H])C(=O)N(C([H])([H])[H])C([H])([H])C([H])([H])OC1=C2C(=NC([H])=NC2=C([H])C([H])=C1[H])N([H])C1=C([H])C(Cl)=C(OC([H])([H])C2=NC([H])=C([H])C([H])=C2[H])C([H])=C1[H]
[H]N(C(=O)C([H])([H])C([H])([H])C1=NC(=NO1)C1=C([H])C([H])=C(F)C([H])=C1[H])C1=C([H])C2=C(C([H])=C1[H])N(C1=C2C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])[H]
[H]OC(=O)[C@@]([H])(C([H])([H])C([H])([H])[H])[C@@]1([H])C2=C([H])C([H])=C(OC([H])([H])C([H])([H])C3=C(OC(=N3)C3=C([H])C([H])=C(Cl)C([H])=C3[H])C([H])([H])[H])C([H])=C2C([H])([H])C1([H])[H]
[H]N(C(=O)C1=C([H])C(C(=O)C([H])([H])[H])=C(N([H])S(=O)(=O)C([H])([H])[H])C([H])=C1[H])[C@]([H])(C(=O)N([H])[C@]1([H])C(=O)C([H])([H])O[C@@]1([H])C([H])([H])C([H])([H])[H])C([H])([H])C1(C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N1C(=O)C2(N(C3=C([H])C([H])=C([H])C([H])=C3[H])C1([H])[H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])OC1=C([H])C([H])=C(F)C([H])=C1[H])C([H])([H])C2([H])[H]
[H]OC1=C([H])C(=C([H])C([H])=C1[H])[C@@]12C3=C(N([H])C4=C3C([H])=C([H])C([H])=C4[H])C([H])([H])[C@@]([H])(N([H])C([H])([H])C1([H])[H])C2([H])[H]
[H]N([H])C1=NC(=C(C(=N1)N(C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C(N([H])C([H])([H])C2=C([H])C([H])=C(C([H])=C2[H])S(=O)(=O)C([H])([H])[H])C([H])=C1[H])C([H])([H])C([H])([H])[H]
CC1=C(Cl)C(C)=C2C(N)=C(SC2=N1)C(=O)NCC1=NC=CC=N1
[H]N([H])C(=NC([H])([H])C([H])([H])C([H])([H])[C@]([H])(N([H])C(=O)[C@]([H])(N([H])C(=O)[C@@]1(N([H])C(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C2=C(C([H])=C([H])C([H])=C2Br)C([H])([H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C(=O)N([H])[C@]([H])(C(=O)N([H])C([H])([H])C(=O)N([H])[H])C([H])([H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H])N([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C(F)C([H])=C1[H])C1=C([H])C(=C([H])C([H])=C1SC1=C([H])C([H])=C([H])C([H])=C1C([H])([H])N([H])C([H])([H])[H])C([H])([H])[H]
[H]N([H])C(=O)C1=NN(C2=C1C([H])([H])C([H])([H])C1=C([H])N=C(N=C21)N([H])C1=C(OC(F)(F)F)C([H])=C([H])C(=C1[H])N1C([H])([H])C([H])([H])N([H])C([H])([H])C1([H])[H])C([H])([H])[H]
[H]C1=C(N(C(=C1C(=O)C([H])([H])OC1=C(N=C(C([H])=C1[H])C([H])([H])[H])[N+]([O-])=O)C([H])([H])[H])[C@]([H])(C([H])([H])[H])C([H])([H])OC([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)N1N=C(C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])[C@@]([H])(C2=C([H])C([H])=C([H])C([H])=C2[H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)[C@]12N([H])C(=O)[C@]3([H])C([H])([H])[C@@]([H])(OC4=C([H])C(=NC5=C([H])C(OC([H])([H])[H])=C([H])C([H])=C45)C4=C([H])C([H])=C([H])C([H])=C4[H])C([H])([H])[C@@]3([H])C(=O)N(C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])\C([H])=C([H])\[C@]1([H])C2([H])[H])S(=O)(=O)C1([H])C([H])([H])C1([H])[H]
[H]N(C1=NN=C(O1)C1=C2N(C([H])=C(C2=C([H])C(F)=C1[H])C([H])([H])[H])C([H])([H])C1=C(Cl)C([H])=C(Cl)C([H])=C1[H])S(=O)(=O)C1=C([H])C([H])=C(F)C(F)=C1[H]
[H]N(C(=O)C([H])([H])OC1=C([H])C([H])=C(\C([H])=C(\[H])C2=C(C(=O)N([H])C(=O)N2[H])[N+]([O-])=O)C([H])=C1[H])C1=C([H])C([H])=C([H])C(=C1[H])C([H])([H])[H]
[H]\C(=C(\[H])C1=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C(OC([H])([H])[H])=C1[H])C1=C([H])C(OC([H])([H])[H])=C([H])C(OC([H])([H])[H])=C1[H]
[H]O[C@@]([H])(C([H])([H])O[C@@]([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])N([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C2C([H])=C([H])C([H])=C([H])C2=C1[H]
[H]N1C2=C(C([H])=C([H])C([H])=C2[H])C2=C1C1=NC([H])=C([H])C([H])=C1N([H])C(=O)C2([H])[H]
[H]N=C(N([H])C1=C(Cl)C(SC([H])([H])[H])=C([H])C(Cl)=C1[H])N(C1=C([H])C([H])=C([H])C(=C1[H])C([H])([H])C([H])([H])[H])C([H])([H])[H]
[H]N(N1C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2C([H])([H])C1([H])[H])C(=O)OC1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
CCOC(=O)C1=C(C2CC2)N2N=C(C=C(C2=C1C(=O)OCC)C1=CC=CC=C1)N1CCOCC1
OOC1=CC=C(SC2=CC=C3C4=C(NCCCC5=CC=CC=C5)C(=O)N=C4C4=C3C2=CC=C4)C=C1
[H]OC1=C([H])C([H])=C2C(ON=C2C2=C([H])C(=C(O[H])C([H])=C2[H])C([H])([H])[H])=C1[H]
[H]N(C1=C(N([H])S(=O)(=O)C(F)(F)F)C([H])=C([H])N=C1[H])C1=C(OC([H])([H])[H])C([H])=C([H])C([H])=C1[H]
[H]N([H])C(=O)C1=C([H])C([H])=C([H])C2=C(Cl)N(N=C12)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N([H])C([H])([H])[H]
[H]C([H])([H])C([H])([H])OC([H])([H])C([H])([H])[N+](C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)C([H])([H])C1=C([H])C([H])=C2OC([H])([H])OC2=C1[H])C1=NN(C(=C1[H])C1=NC2=C(N1[H])N(C(=O)N(C2=O)C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])[H]
[H]OC1=C([H])C([H])=C2N([H])C([H])=C(C2=N1)C1=C([H])C([H])([H])N([H])C([H])([H])C1([H])[H]
[H]N(C(=O)N1C([H])([H])C([H])([H])C([H])(OC2=C([H])C([H])=C([H])C([H])=C2Cl)C([H])([H])C1([H])[H])C1=C([H])C([H])=C([H])C(=C1[H])C1=NC([H])=C([H])N1[H]
[H]N1C([H])=C([H])C2=C([H])C([H])=C(C([H])=C12)N1C([H])([H])C([H])([H])N(C(=O)C2=NC(C3=C([H])C([H])=C(C([H])=C3[H])C([H])([H])[H])=C(C([H])=N2)C2=C([H])C([H])=C(OC([H])([H])[H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]OC([H])([H])[C@@]1([H])O[C@@]([H])(C2=C([H])C(=C(Cl)C([H])=C2[H])C([H])([H])C2=C([H])C([H])=C(SC([H])([H])[H])N=N2)[C@]([H])(O[H])[C@@]([H])(O[H])[C@]1([H])O[H]
[H]O[C@]([H])(C([H])([H])N(C([H])([H])C([H])([H])OC([H])([H])C([H])([H])[H])S(=O)(=O)C1=C(C([H])=C([H])C([H])=C1C([H])([H])[H])C([H])([H])[H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])[C@]2(OC3=C([H])C([H])=C(C#N)C([H])=C3C([H])([H])C2([H])[H])C1([H])[H]
[H]N(C(=O)C([H])([H])OC1=C([H])C([H])=C2N([H])C(=O)C(C#N)=C(C2=C1[H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])C(Cl)=C(Cl)C([H])=C1[H]
[H]C1=C(C(=O)C2=C([H])C([H])=C(C([H])=C2[H])C([H])([H])N2C(=NC3=C2C([H])=C([H])N=C3[H])C([H])([H])[H])C2=C([H])C([H])=C(C([H])=C2N1C(=O)N(C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]N(C(=O)C1=C([H])C([H])=C([H])O1)C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C2=C([H])C([H])=C(C([H])=C12)S(=O)(=O)N([H])C([H])([H])[H]
[H]N([H])[C@]([H])(C([H])([H])OC1=C([H])N=C([H])C(=C1[H])C1=C([H])C2=C(C([H])=NC([H])=C2[H])C([H])=C1[H])C([H])([H])C1=C([H])N([H])C2=C([H])C([H])=C([H])C([H])=C12
[H]N1C([H])([H])C([H])([H])C2=NC(=NC([H])=C2C([H])([H])C1([H])[H])C([H])([H])C1=C([H])C(Cl)=C([H])C([H])=C1[H]
[H]C1=NN(C([H])=N1)C([H])([H])C1=C(N(N=C1C(=O)N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C([H])C([H])=C1Cl)C1=C([H])C([H])=C(Br)C([H])=C1[H]
[H]O[C@]([H])(C([H])([H])C(=O)N([H])C([H])([H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])N([H])C([H])=N1)C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(C(=O)C(=O)[C@@]([H])(N([H])C(=O)C([H])([H])C([H])([H])C(=O)C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1OC([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC([H])([H])[C@@]1([H])O[C@@]([H])(N2C([H])=NC3=C2N=C(N=C3N([H])[C@]2([H])OC([H])([H])C([H])([H])C2([H])[H])N2N=C([H])C(=C2[H])C(=O)N([H])C([H])([H])C([H])([H])C([H])([H])[H])[C@]([H])(O[H])[C@]1([H])O[H]
[H]N(C(=O)C([H])([H])C([H])([H])[N+]1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C(\C([H])=C2\C3=NC4=C([H])C(Cl)=C([H])C([H])=C4C(=O)N3C([H])([H])C([H])([H])C2([H])[H])C([H])=C1[H]
[H]OC(=O)C([H])(C(=O)O[H])C([H])([H])C1([H])N([H])C(=O)C([H])([H])S(=O)C([H])([H])C([H])(N([H])C(=O)C([H])(N([H])C(=O)C([H])(N([H])C(=O)C([H])([H])N([H])C(=O)C([H])(N([H])C(=O)C([H])(N([H])C(=O)C2(N([H])C(=O)C([H])(N([H])C(=O)C([H])(N([H])C1=O)C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(O[H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C(=O)N([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(O[H])C([H])=C1[H])C(=O)N([H])[H]
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[H]N1C(=O)N(C(=O)C2=C([H])C(Br)=C([H])C([H])=C12)C([H])([H])C([H])([H])C([H])([H])N1C([H])=NC([H])=C1[H]
[H]O[C@]([H])([C@]([H])(C([H])([H])[H])C([H])([H])C(\[H])=C(/[H])C([H])([H])C([H])([H])[H])[C@]1([H])N(C(=O)[C@@]([H])(N(C(=O)[C@@]([H])(N(C(=O)[C@@]([H])(N(C(=O)[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@]([H])(N(C(=O)[C@]([H])(N([H])C(=O)[C@]([H])(N(C(=O)C([H])([H])N(C(=O)[C@@]([H])(N([H])C1=O)C([H])([H])C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H]
[H]OC(=O)C1=C([H])C(=C([H])C([H])=C1N([H])C(=O)C1([H])C([H])([H])C1([H])[H])N(C([H])([H])[H])C([H])([H])C1=C([H])N=C([H])C([H])=C1[H]
[H]N(N([H])C(=O)C1=C([H])C([H])=C(N([H])C(=O)C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])=C1[H])C(=O)N([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC(=O)[C@@]([H])(N([H])S(=O)(=O)C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])N([H])C(=O)C1=C([H])C2=C(S1)C([H])([H])C([H])([H])N(C2=O)C([H])([H])C([H])([H])C1([H])C([H])([H])C([H])([H])N([H])C([H])([H])C1([H])[H]
[H]C1=NC([H])=C(C(OC2=C([H])C([H])=C3SC([H])([H])C([H])([H])C3=C2[H])=C1[H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H]
[H]N(C([H])([H])C([H])([H])N1C(=O)C2(N(C3=C([H])C([H])=C([H])C([H])=C3[H])C1([H])[H])C([H])([H])C([H])([H])N(C([H])([H])C2([H])[H])[C@]1([H])C2=C([H])C(Cl)=C(Cl)C([H])=C2C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C1([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]N([H])C([H])([H])C([H])([H])C(=O)N([H])[C@@]([H])(C(=O)N1C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])C1(C([H])([H])N([H])C(=O)N([H])C2=C([H])C([H])=C(C([H])=C2[H])C(=O)OC([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C(Cl)C([H])=C1Cl
[H]OC(=O)C1=C(C(=O)C2=C(O[H])C([H])=C(C([H])=C2O[H])C(=O)OC([H])([H])[C@@]([H])(N([H])S(=O)(=O)C2=C([H])C3=C(C([H])=C([H])C([H])=C3[H])C([H])=C2[H])C([H])([H])C2=C([H])C([H])=C(O[H])C([H])=C2[H])C(O[H])=C([H])C([H])=C1[H]
[H]N1C([H])=C(N=C1[C@@]1([H])N([H])[C@@]([H])(C2=C(C3=C([H])C([H])=C([H])C([H])=C3N2[H])C1([H])[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C1=C([H])C(Cl)=C(S1)C1=NC(=NO1)C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]N(C1=NC2=C(SC(=C2[H])N(C([H])([H])[H])C([H])([H])[H])C(=N1)C(=O)C1=C([H])C([H])=C([H])S1)C([H])([H])C1=C([H])C([H])=C([H])N=C1[H]
[H]N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@]1([H])N([H])C(=O)[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])[H])C([H])([H])C2=C([H])C([H])=C(Cl)C([H])=C2[H])C([H])([H])SSC1([H])[H])C([H])([H])C1=C([H])C([H])=C([H])N=C1[H])C([H])([H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C2C([H])=C([H])C([H])=C([H])C2=C1[H]
[H]C1=C(N2C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C2([H])[H])C2=C(C([H])=C([H])C(Br)=C2[H])N1S(=O)(=O)C1=C([H])C([H])=C(C([H])=C1[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])C(=C([H])C([H])=C1N1C([H])([H])C([H])([H])N(C(=O)C2=C([H])C(=C([H])C([H])=C2O[C@@]([H])(C([H])([H])[H])C(F)(F)F)S(=O)(=O)C([H])([H])[H])C([H])([H])C1([H])[H])C([H])([H])[H]
[H]N(C1=NC([H])=C(C(=N1)C1=C([H])C([H])=C(F)C(Cl)=C1[H])C([H])([H])[H])C1=C([H])C([H])=C(N2C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C2([H])[H])C(F)=C1[H]
COC1=CC2=C(CN(C[C@]3(CC(=O)NC3=O)C#CC3=NC(=CC=C3)N3CCSCC3)C2=O)C=C1
[H]C1=C([H])C([H])=C2C(SC(=C2C([H])([H])C([H])([H])N2C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])OC2=C([H])C([H])=C(Cl)C([H])=C2[H])=C1[H]
[H]OC1=C([H])C2=C(C([H])=C1O[H])[C@@]([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])N([H])C([H])([H])C2([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C(C([H])=C1[H])C1=C(C(F)=C([H])C(=C1[H])C(=O)N([H])C1([H])C([H])([H])C1([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])SC(=N1)C([H])([H])[H]
[H]N(C(=O)C(=O)[C@@]([H])(N([H])C(=O)O[C@]1([H])C(=O)N(C(=O)C2=NC3=C(S2)C([H])=C([H])C([H])=C3[H])C([H])([H])C1(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C1=NN([H])C([H])=C1[H]
[H]N([H])C1=C([H])C(OC([H])([H])[C@@]2([H])OC([H])([H])C([H])([H])N(C([H])([H])C3=C([H])C([H])=C(Cl)C([H])=C3[H])C2([H])[H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]OC(=O)[C@]([H])(N(C(=O)C(\[H])=C(/[H])C1=C([H])C([H])=C2OC([H])([H])OC2=C1[H])C([H])([H])C1=C(Cl)C([H])=C2OC([H])([H])OC2=C1[H])C([H])([H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H]
[H]OC1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[C@]([H])(N1C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C2=C([H])C([H])=C([H])C(=C2[H])C([H])([H])[H])[C@]([H])(C1([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])N([H])C([H])([H])[H]
[H]N([H])C(=O)C1=NN(C2=C1C([H])([H])C([H])([H])N(C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1C([H])([H])N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H])C2=O)C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]N(C(=O)O[C@@]1([H])[C@@]2([H])C([H])([H])[C@]3([H])C([H])([H])[C@]([H])(C2([H])[H])C([H])([H])[C@@]1([H])C3([H])[H])[C@@](C(=O)N(C([H])([H])[H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])(C([H])([H])[H])C([H])([H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H]
[H]C1=C([H])C2=C(O1)C([H])=C([H])C(=C2[H])S(=O)(=O)N1C([H])([H])C([H])(C(=O)N2C([H])([H])C([H])([H])N(C3=C([H])C([H])=NC([H])=C3[H])C([H])([H])C2([H])[H])C1([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])N(C(=O)N1OC(=O)C(=C1C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H]
[H]N=C(N([H])[H])N([H])\N=C(\C1=C([H])C([H])=C([H])C([H])=C1[H])[C@]1([H])S[C@@]([H])(Cl)C([H])([H])C1([H])[H]
[H]OC(=O)C([H])([H])N(C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]1([H])N(C(=O)[C@@]([H])(N([H])[H])[C@]([H])(O[H])C([H])([H])[H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=N[H])N([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=N[H])N([H])[H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=N[H])N([H])[H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=N[H])N([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])[H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=N[H])N([H])[H])C([H])([H])[H]
OC(=O)C1CCN(CC2=COC3=CC(OC4=NC5=NC=CC=C5S4)=CC=C23)CC1
[H]N(C1=NC([H])=C(S1)C#N)C1=C([H])C([H])=C([H])C([H])=N1
[H]C1=C([H])C(OC([H])([H])[H])=C(C([H])=N1)N1N(C(=C(C1=O)C([H])([H])N(C([H])([H])C([H])([H])C1=C([H])C([H])=C(Cl)C([H])=C1[H])C1([H])C([H])([H])C([H])([H])N(C(=O)C2=C(F)C([H])=C([H])C([H])=C2F)C([H])([H])C1([H])[H])C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])C([H])=C2C(=C1[H])C([H])([H])C([H])(C([H])([H])C(=O)N1C([H])([H])SC([H])([H])[C@@]1([H])C(=O)N1C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C#N)C2([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C2N([H])N=C([H])C2=C1[H])[C@]([H])(C1=C([H])C(Cl)=C(Cl)C([H])=C1[H])C1([H])C([H])([H])C([H])([H])N([H])C([H])([H])C1([H])[H]
[H]N=C(N([H])[H])N([H])C([H])([H])C([H])([H])C([H])([H])[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C([H])([H])C(=O)OC1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=N[H])N([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])C(=O)N([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])[H]
[H]OC1=C([H])C(=C(C(=C1[H])C([H])([H])[H])C([H])([H])[C@]([H])(N([H])[H])C(=O)N1C([H])([H])C2=C(C([H])=C([H])C([H])=C2[H])C([H])([H])[C@]1([H])C(=O)N([H])[H])C([H])([H])[H]
[H]N([H])C1=C([H])N=C(N(C1=O)C([H])([H])C(=O)N([H])[C@@]([H])(C(=O)C1=NN=C(O1)C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]O[C@@]1([H])[C@@]([H])(S[C@]([H])(C(=O)N2C([H])([H])C([H])([H])SC([H])([H])C2([H])[H])[C@@]1([H])O[H])N1C([H])=NC2=C1N=C(Cl)N=C2N([H])C([H])([H])C1=C([H])C([H])=C([H])C(I)=C1[H]
[H]N(C(=O)[C@]1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C(=O)N1C([H])([H])C([H])([H])N(C2=NC3=C(S2)C([H])=C([H])C([H])=C3[H])C([H])([H])C1([H])[H])C1(C#N)C([H])([H])C1([H])[H]
[H]N1C(=NC2=C(C([H])=C(C([H])=C12)C(F)(F)F)C1=C([H])C([H])=C(OC([H])([H])[H])N=C1[H])N1C([H])([H])C([H])([H])N(C2=NC([H])=C([H])C([H])=C2C(F)(F)F)C([H])([H])C1([H])[H]
[H]C1=C(OC([H])([H])[H])C(OC([H])([H])[H])=C([H])C2=C1S[C@@]([H])(C(=O)C([H])([H])C([H])([H])[C@@]1([H])C([H])([H])C([H])([H])[N@@+](C([H])([H])[H])(C([H])([H])C(=O)OC([H])([H])[H])C([H])([H])C1([H])[H])C2([H])[H]
[H]N(C(=O)C1([H])C([H])([H])C1([H])[H])C1=NC2=C(S1)C([H])=C(C([H])=C2[H])C(=O)N([H])C1=C(Cl)C([H])=C([H])C([H])=C1C([H])([H])[H]
O=C(NC1=CC=C(C=C1)C1=CNN=C1)N1CCC2=C(C1)C=CC=C2
[H]ON([H])C(=O)[C@]([H])(N([H])S(=O)(=O)C1=C([H])C([H])=C([H])C2=C(C([H])=C([H])C([H])=C12)N(C([H])([H])[H])C([H])([H])[H])C([H])([H])N([H])S(=O)(=O)C1=C2C([H])=C([H])C([H])=C(N(C([H])([H])[H])C([H])([H])[H])C2=C([H])C([H])=C1[H]
[H]C1=C([H])C(C2=NN(C3=C2N=C(C([H])=C3N(C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])=C(Cl)C([H])=C1OC([H])([H])[H]
[H]N=C(N([H])[H])C1=C([H])C2=C([H])C(=C([H])C([H])=C2C([H])=C1[H])C([H])([H])N1C2=C([H])C(OC3([H])C([H])([H])C([H])([H])N(C(=N[H])C([H])([H])[H])C([H])([H])C3([H])[H])=C([H])C([H])=C2N=C1C([H])(C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])OC1=C([H])C([H])=C([H])C([H])=C1[C@@]1([H])N(N=C(C2=C([H])C([H])=C(C([H])=C2[H])S(=O)(=O)C([H])([H])[H])C1([H])[H])C(=O)C([H])([H])[H]
[H]ON([H])C(=O)C(\[H])=C(/[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N(C([H])([H])C([H])([H])C1=C2C([H])=C([H])C([H])=C([H])N2N=C1C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])N(C([H])([H])C1=C(N=C2N1C([H])([H])C([H])([H])C([H])([H])N2C1=C(C([H])=C(C([H])=C1C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C(F)(F)F)C([H])([H])C(F)(F)F
[H]C1=C([H])C(=C([H])C([H])=C1C#CC([H])([H])C([H])([H])N1C([H])([H])C([H])([H])SC([H])([H])C1([H])[H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(C(=O)N([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])(C2=C([H])N([H])C3=C([H])C(F)=C([H])C([H])=C23)C([H])([H])C1([H])[H])C1=C([H])C([H])=C(OC([H])([H])[H])C(=C1[H])N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H]
[H]O[C@]([H])(C([H])([H])[H])[C@]([H])(N([H])C(=O)[C@]1([H])N([H])C(=O)[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])[H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])SSC1([H])[H])C([H])([H])C1=C([H])N([H])C(=N1)C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])N=C(N([H])[H])N([H])[H])C([H])([H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H])C(=O)N([H])[H]
[H]N(C([H])([H])C(\[H])=C(/C([H])([H])[H])C([H])([H])C([H])([H])C(\[H])=C(/C([H])([H])[H])C([H])([H])C([H])([H])C([H])=C(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
COC1=CC=C(C=C1)C(=O)CC(NC1=CC=C(C=C1)N(O)=O)C1CCCCC1
[H]OC([H])([H])C1=C([H])C([H])=C2N(C3=C(C2=C1[H])C1=C(C(=O)N([H])C1([H])[H])C1=C3C([H])([H])C2=C1C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C([H])([H])O[H]
[H]ON([H])C(=O)[C@]([H])(N([H])S(=O)(=O)C1=C([H])C([H])=C(Cl)S1)C([H])(C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])C(OC([H])([H])C([H])([H])OC2=C(N=C(C([H])=C2[H])C([H])([H])[H])[N+]([O-])=O)=C(OC([H])([H])[H])C([H])=C1Cl