[H]C1=C([H])C([H])=C(C([H])=C1[H])C1=NN(C(=O)C2=C([H])C(F)=C(F)C([H])=C2[H])C([H])([H])C([H])([H])C1([H])[H]
[H]OC(=O)C([H])([H])N(C(=O)C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
CN1C(C)=C(C(=O)N(C)C1=O)C1=CC=C(C[C@H](NC(=O)C2=C(Cl)C=CC=C2Cl)C(O)=O)C=C1C
[H]OC1=C([H])C([H])=C(OC2=C(C([H])=C(C([H])=C2[H])C([H])([H])C([H])([H])N([H])[H])C([H])([H])[H])C([H])=C1[H]
[H]N(C([H])([H])[H])C1([H])C([H])([H])N(C(=O)C2=C([H])C3=C(N2[H])C(=C([H])C(Cl)=C3[H])C([H])([H])[H])C1([H])[H]
[H]OC(=O)C([H])([H])OC1=C([H])C(=C([H])C([H])=C1[H])C([H])([H])N([H])C(=O)[C@@]1([H])N(N=C([H])C1([H])[H])C(=O)C([H])([H])[C@]([H])(N([H])[H])C([H])([H])C1=C(F)C([H])=C(F)C(F)=C1[H]
[H]O[C@]1([H])C([H])([H])C2=C(C([H])=C([H])C([H])=C2N([H])C2=NC([H])=C(O2)C2=C([H])C([H])=C([H])C(=C2[H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N([H])S(=O)(=O)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N([H])C(=S)N([H])[C@]1([H])O[C@]([H])(C([H])([H])OC(=O)C([H])([H])[H])[C@@]([H])(OC(=O)C([H])([H])[H])[C@]([H])(OC(=O)C([H])([H])[H])[C@@]1([H])OC(=O)C([H])([H])[H]
[H]C1=C([H])C(OC([H])([H])C2=C([H])C([H])=C(Cl)C([H])=C2[H])=C(Br)C(=O)N1C([H])([H])C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]C1=C([H])C2=C3C(=C([H])C([H])=C([H])C3=C1[H])S(=O)(=O)N2C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C([H])C([H])=C(C([H])=C2[H])[N+]([O-])=O)C([H])([H])C1([H])[H]
[H]OC([H])([H])C([H])([H])C([H])([H])OC1=C([H])C([H])=C(OC([H])([H])C2=C([H])C(=C([H])C([H])=C2[H])C(F)(F)F)C([H])=C1C(=O)C([H])([H])[H]
[H]N1C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C(C([H])=C2[H])C2=C(C([H])=C([H])C([H])=C2[H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])OC([H])([H])[H])S(=O)(=O)C2=C([H])C([H])=C(F)C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N1C2=C([H])C(Cl)=C([H])C([H])=C2C([H])([H])[C@]([H])(C1=O)[N+]([O-])=O
[H]OC1=C([H])C([H])=C(OC([H])([H])[C@@]([H])(O[H])C([H])([H])N([H])C([H])([H])C([H])([H])C2=C([H])C([H])=C(N([H])[H])C([H])=C2[H])C([H])=C1[H]
[H]N(C(=O)C([H])([H])N1C([H])=C([H])C2=C(N([H])C(=O)N(C2=O)C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C1=O)[C@@]([H])(C(=O)C(F)(F)F)C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)C1=C([H])N(C2=C([H])C(SC3=C([H])C([H])=C([H])C([H])=C3[H])=C([H])C([H])=C2C1=O)C([H])([H])[H])[C@]1([H])C(C([H])([H])[H])(C([H])([H])[H])[C@@]2([H])C([H])([H])C([H])([H])[C@]1(C([H])([H])[H])C2([H])[H]
[H]OC([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=O)C1=NN(C(N2C(=C([H])C([H])=C2C([H])([H])[H])C([H])([H])[H])=C1C([H])([H])[H])C1=C(Cl)C([H])=C(Cl)C([H])=C1[H]
[H]N(C(=O)OC([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])[C@]([H])(C(=O)N([H])[C@]([H])(C([H])=O)C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)C([H])([H])OC1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])[H])C1=C([H])C(=O)\C(C([H])=C1[H])=C1\OC2=C([H])C([H])=C([H])C([H])=C2N1[H]
[H]N1C([H])=NC(=C1[H])C([H])([H])C([H])([H])C([H])([H])OC1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])C(=O)C([H])([H])[H]
[H]N(C1=C2N([H])C([H])=C(C2=C(C([H])=N1)C(=O)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C([H])([H])[H])C1=C([H])C([H])=C([H])C(OC([H])([H])[H])=C1[H]
[H]N1C([H])([H])C2=C(ON=C2OC([H])([H])[H])C([H])([H])C([H])([H])C1([H])[H]
[H]OC(C([H])([H])[H])(C([H])([H])[H])[C@@]([H])(N([H])C1=NC([H])=C([H])C(=N1)N(C(=O)N([H])C1=C([H])C([H])=C([H])C([H])=C1C([H])([H])[H])C1=C([H])C([H])=C(F)C([H])=C1[H])C([H])([H])[H]
[H]N(C(=O)N1C([H])([H])C([H])([H])C([H])(N([H])S(=O)(=O)C2=C([H])C([H])=C(F)C([H])=C2[H])C([H])([H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C(Cl)C([H])=C1Cl
[H]N(C(=O)C([H])([H])[H])C1=C([H])C(=C([H])C([H])=N1)C1=C(N=C(SC([H])([H])[H])N1C([H])([H])C([H])([H])C([H])([H])Cl)C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]N=C(N([H])[H])N([H])C([H])([H])C([H])([H])C([H])([H])[C@]([H])(N([H])C(=O)C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C(=N[H])N([H])[H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=N[H])N([H])[H])C([H])([H])N([H])[H]
[H]ON([H])C(=O)C1=C([H])C2=C(C([H])=C1[H])C([H])([H])C([H])([H])C1=C2C([H])=C([H])C([H])=C1[H]
[H]N1C([H])=C(C2=C1C([H])=C([H])C([H])=C2[H])C1=C(C(=O)N([H])C1=O)C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H]
[H]N(C(=O)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N([H])S(=O)(=O)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H])C([H])([H])C([H])([H])N(C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])[H]
[H]C1=C(N2C([H])=C([H])C(N3C([H])([H])C([H])([H])N(C4=NC([H])=C([H])C([H])=N4)C([H])([H])C3([H])[H])=C(C#N)C2=N1)C([H])([H])C([H])([H])C1([H])C([H])([H])C1([H])[H]
[H]OC(=O)C([H])([H])C([H])([H])[C@]([H])(N([H])C(=O)C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)N([H])[H])C(=O)O[H]
[H]N(C(=O)C1=C([H])N=C([H])C([H])=C1[H])[C@@]([H])(C(=O)N1C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])OC2=C([H])C([H])=C(C3=NOC(=N3)C3=C([H])C([H])=C([H])C([H])=C3[H])C(F)=C2[H])C([H])([H])C1([H])[H])C([H])([H])[H]
[H]N([H])S(=O)(=O)C1=C([H])C([H])=C(C([H])=C1[H])N1N=C(C2=C1C1=C([H])C([H])=C([H])C([H])=C1C([H])([H])C2([H])[H])C(F)(F)F
[H]N(C(=O)N(C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])SC1=NC(=C(N1[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]ON([H])C(=O)C1(C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])S(=O)(=O)C1=C([H])C([H])=C(OC2=C([H])C(=C([H])C([H])=C2[H])C(F)(F)F)C([H])=C1[H]
[H]O[C@]([H])(C([H])([H])OC1=C([H])C([H])=C([H])C([H])=C1F)C([H])([H])N([H])C([H])([H])[C@]1([H])OC2=C([H])C([H])=C([H])C([H])=C2OC1([H])[H]
[H]C1=C([H])N2C(=C1[H])C([H])([H])[C@]([H])(N(C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C2([H])[H]
[H]N(C(=O)C(=O)[C@@]([H])(N([H])C(=O)OC([H])([H])C1(C([H])([H])C([H])([H])[H])C([H])([H])OC1([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C1=NN([H])C(=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C(C#N)=C([H])C(=C1[H])C([H])([H])N1N=C([H])N=C1[H]
[H]OC(=O)C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)N([H])[C@]1([H])C([H])([H])C([H])([H])[C@]([H])(C1([H])[H])[C@]([H])(N([H])[H])C(=O)N1C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
CC1=CC=C(C=C1C)C(SCCN)(C1=CC=CC=C1)C1=CC=CC=C1
[H]N([H])C1=NOC2=C([H])C([H])=C(C([H])=C12)N1N=C(C([H])=C1C(=O)N1C2=C(C([H])=C(C([H])=C2[H])C2=C([H])C([H])=C([H])C([H])=C2C([H])([H])N2C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H])C(F)(F)F
[H]N(C(=O)C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C1=NN([H])C(=N1)C(=O)OC([H])([H])[H]
[H]OC(=O)C([H])([H])[C@]([H])(N([H])C(=O)C([H])([H])N(C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C([H])([H])[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])[H])C([H])([H])C1=C([H])C([H])=C(O[H])C([H])=C1[H])C([H])([H])C([H])([H])SC([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])N([H])C([H])=N1)C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C(=O)N([H])[H]
[H]N(C1=C2C([H])=C([H])C([H])=C([H])C2=NC2=C1C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C([H])([H])OC([H])([H])C([H])([H])OC([H])([H])C([H])([H])N([H])C1=C2C([H])=C([H])C([H])=C([H])C2=NC2=C1C([H])([H])C([H])([H])C([H])([H])C2([H])[H]
[H]C1=C([H])C2=C(C([H])=C1[H])C1=C(C([H])=C2OC([H])([H])[H])C(=NC2=C([H])C([H])=C([H])C([H])=C12)N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H]
[H]C1=C([H])N(C([H])=N1)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1C([H])([H])C([H])([H])C2(N(C(=O)N(C2=O)C2=C([H])C(OC([H])([H])[H])=C([H])C([H])=C2[H])C([H])([H])C2=C(F)C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]C1=NC([H])=C([H])C(=C1[H])C1=NOC(=N1)C1=C([H])C([H])=C([H])C([H])=C1OC([H])([H])[H]
[H]OC(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C(\[H])=C(\C1=C([H])C([H])=C([H])N=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC(=C([H])O1)C(=O)N([H])C([H])([H])C([H])([H])C([H])([H])OC([H])([H])C([H])([H])OC([H])([H])[H]
[H]C1=C(C2=C(N1C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])[H])C2([H])[H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]C1=NC2=C(C([H])=C([H])C([H])=C2C(C2=C([H])C(=C([H])C([H])=C2[H])C2=C([H])C([H])=C(C([H])=C2[H])S(=O)(=O)C([H])([H])[H])=C1C([H])([H])[H])C(F)(F)F
[H]ON([H])C(=O)[C@]1([H])N(C([H])([H])C([H])([H])N(C1([H])[H])S(=O)(=O)C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])S(=O)(=O)C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]C1=NN(C2=C1C([H])=C(C([H])=C2[H])C1=C([H])C(C#N)=C([H])C([H])=C1[H])C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]C1=C([H])C(=C([H])C(=C1[H])C1=NC2=NC(=C([H])C([H])=C2C([H])=N1)C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])C2=C(C([H])=C1Br)C([H])([H])C([H])([H])C1=C(C(=O)C([H])([H])C([H])([H])N21)C([H])([H])[H]
[H]N=C(N([H])[H])N([H])C([H])([H])C([H])([H])C([H])([H])[C@]1([H])N(C(=O)[C@@]([H])(C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])[C@]2([H])N([H])C([H])([H])C3=C(C([H])=C([H])C([H])=C3[H])C2([H])[H])C([H])([H])[C@]([H])(OC([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C1([H])[H]
[H]N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(\[H])=C(/[H])S(=O)(=O)C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]OC(=O)[C@]([H])(N1C([H])([H])[C@]([H])(C2=C([H])C(F)=C([H])C([H])=C2[H])[C@@]([H])(C([H])([H])N2C([H])([H])C([H])([H])C([H])(C3=C([H])C(=NN3C([H])([H])C([H])([H])[H])C([H])([H])C3=C([H])C(F)=C([H])C(F)=C3[H])C([H])([H])C2([H])[H])C1([H])[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(C(=O)N([H])S(=O)(=O)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H])C1(C([H])([H])C2=C([H])C(=C(C([H])=C2[H])N2C(=O)C3=C(OC([H])([H])C([H])([H])[H])C4=C([H])C([H])=C([H])C([H])=C4C(OC([H])([H])C([H])([H])[H])=C3C2([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]OC(=O)C([H])([H])OC1=C([H])C([H])=C([H])C(=C1[H])[C@]([H])(OC(=O)[C@@]1([H])N(C(=O)C(=O)C2=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C(OC([H])([H])[H])=C2[H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C([H])([H])C1=C([H])C([H])=C(OC([H])([H])[H])C(OC([H])([H])[H])=C1[H]
[H]N(C(=O)C([H])([H])C1=C([H])C(Br)=C([H])C(Br)=C1[H])C([H])([H])[C@]([H])(C([H])([H])OC(=O)C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
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[H]N=C(N([H])[H])N([H])C(=O)C1=C([H])C([H])=C(O1)C1=C(F)C(F)=C([H])C([H])=C1[H]
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[H]N(\N=C(/[H])C1=C([H])C(OC([H])([H])[H])=C(OC2=NC([H])=C(C([H])=C2[H])[N+]([O-])=O)C([H])=C1[H])C(=O)C1=C([H])C(OC([H])([H])[H])=C([H])C([H])=C1[H]
[H]OC1=C([H])C([H])=C2N(C(=O)N=C(C3=C([H])C([H])=C(C([H])=C3[H])C([H])(C([H])([H])[H])C([H])([H])[H])C2=C1C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
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[H]N=C(N([H])C([H])([H])C([H])([H])C1=C([H])N([H])C([H])=N1)C([H])([H])[C@]([H])(C1=C([H])C([H])=C([H])C([H])=N1)C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]C1=C([H])C([H])=[N+](C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])O[C@@]1([H])O[C@]([H])(C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C1([H])[H]
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[H]OC(=O)[C@]12C([H])([H])C([H])([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[C@@]1([H])C1=C([H])C([H])([H])[C@]3([H])[C@@]4(C([H])([H])[H])C([H])([H])[C@@]([H])(O[H])[C@]([H])(O[H])C(C([H])([H])[H])(C([H])([H])[H])[C@]4([H])C([H])([H])C([H])([H])[C@@]3(C([H])([H])[H])[C@]1(C([H])([H])[H])C([H])([H])C2([H])[H]
[H]N([H])C(=O)C(=O)C1=C(N(C2=C([H])C([H])=C([H])C(OC([H])([H])C(=O)N([H])S(=O)(=O)C3=C([H])C([H])=C([H])C([H])=C3[H])=C12)C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])C(=C([H])C([H])=C1Br)C([H])([H])SC1=NC2=C(N1C([H])([H])[H])C(=O)N(C(=O)N2C([H])([H])[H])C([H])([H])[H]
[H]N([H])[C@]([H])(C(=O)N([H])C([H])([H])C([H])([H])N([H])C1=C2C([H])=C([H])C([H])=C([H])C2=NC2=C1C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H]
[H]N(C(=O)C1=C(C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C(=O)N1C2=C(SC([H])=C2[H])N(C([H])([H])C([H])([H])N2C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C([H])([H])C1([H])[H]
[H]N1C(=O)C([H])=C(C2=C1C([H])=C([H])C(=C2[H])N(C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C(F)(F)F)C(F)(F)F
[H]OC1=C([H])C2=C(C([H])=O)C([H])=C(C([H])=C2C([H])=C1[H])C1=C([H])C([H])=C(O[H])C(F)=C1[H]
[H]OC(=O)C([H])([H])C([H])([H])C([H])([H])C#CC1=NC2=C(N=C([H])N2[C@]2([H])[C@]3([H])C([H])([H])[C@]3(C(=O)N([H])C([H])([H])[H])[C@]([H])(O[H])[C@]2([H])O[H])C(=N1)N([H])C([H])([H])C1=C([H])C(Cl)=C([H])C([H])=C1[H]
[H]C([H])=C([H])C([H])([H])N([H])C(=O)C1=C([H])N=C2C(OC([H])([H])[H])=C([H])C([H])=C([H])C2=C1N([H])C1=C(C([H])=C([H])C([H])=C1[H])C([H])([H])[H]
[H]C1=C(SC(=C1[H])C1=C([H])C([H])=C([H])C([H])=C1OC([H])([H])[H])C(=O)N(C([H])([H])[H])[C@]1([H])C([H])([H])N(C(=O)N(C([H])([H])[H])[C@@]2([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]C([H])=C([H])C([H])([H])N([H])C(=O)N([H])[C@@]1([H])C([H])([H])C([H])([H])[C@](C2=C([H])C([H])=C([H])C([H])=C2[H])(C([H])([H])N([H])C(=O)C2=C([H])C([H])=C([H])C([H])=C2OC([H])([H])[H])C([H])([H])C1([H])[H]
[H]C1=C(C2=C(N=C(N(C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[H])N(C2=O)C([H])([H])[H])N1C([H])([H])[H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1OC([H])([H])[H]
[H]N([H])[C@]([H])(C1=C(C([H])=C([H])C(=C1[H])C([H])([H])[H])N1C([H])([H])C([H])([H])N(C(=O)[C@@]2([H])N(C(=O)C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[C@]2([H])C2=C([H])C([H])=C(Cl)C([H])=C2[H])C([H])([H])C1([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]OC(=O)C1=C([H])C([H])=C(C([H])=C1[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])N([H])S(=O)(=O)C1=C([H])C2=C(C([H])=C([H])C(OC([H])([H])C3=NC4=C([H])C([H])=C([H])C([H])=C4C([H])=C3[H])=C2[H])C([H])=C1[H]
[H]N(C1=NC([H])=C([H])C(=N1)C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=N2)C1=C([H])C([H])=C([H])C([H])=C1Cl
[H]C1=C([H])C(=C([H])C2=C1OC(=N2)N1C([H])([H])C([H])([H])N(C(=O)C2([H])C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])C([H])([H])C([H])([H])C1([H])[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]N([H])S(=O)(=O)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])N([H])C(=O)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N(C([H])([H])C([O-])=O)C([H])([H])C([O-])=O
[H]N(C1=C([H])C(Cl)=C(F)C([H])=C1[H])C1=NC([H])=NC2=C([H])C(OC([H])([H])[H])=C(OC([H])([H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H])C([H])=C12
[H]OC(=O)C1=C([H])C(N([H])C(=O)C(\C#N)=C(/[H])C2=C([H])C([H])=C(OC([H])([H])C3=C([H])C([H])=C(F)C([H])=C3[H])C([H])=C2[H])=C([H])C([H])=C1[H]
[H]OC1=C([H])C([H])=C([H])C([H])=C1C(=O)N([H])C(=O)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]N(C(=O)C1=C(SSC2=C(C(=O)N([H])C([H])([H])[H])C3=C(C([H])=C([H])C([H])=C3[H])N2C([H])([H])[H])N(C2=C1C([H])=C([H])C([H])=C2[H])C([H])([H])[H])C([H])([H])[H]
COC1=CC=C2N(C(=CC2=C1)S(=O)(=O)N1CCC(CNS(=O)(=O)C(F)(F)F)CC1)S(=O)(=O)C1=C(F)C=CC=C1
[H]N(C1=C2C(=NC3=C([H])C([H])=C([H])C([H])=C13)C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])SC1=C2C(=NC3=C([H])C(Cl)=C([H])C(Cl)=C13)C([H])([H])C([H])([H])C([H])([H])C2([H])[H]
[H]N(C(=O)C([H])([H])[H])C1=NC(=C([H])S1)[C@]([H])(C(=O)N([H])C([H])([H])C1=C([H])C(=C([H])C(=C1[H])C(F)(F)F)C(F)(F)F)C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])(N2C([H])=NC3=C2C([H])=C([H])C([H])=C3[H])C([H])([H])C1([H])[H]
[H]OC1=C(Cl)C([H])=C(C([H])=C1Cl)C([H])([H])N1C2=C(N=C1C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])=C([H])C([H])=C2[H]
[H]N1C([H])=C(C2=C1C([H])=C([H])C([H])=C2[H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])C([H])([H])N2C(=O)N3C(=C(C2=O)C2=C([H])C([H])=C(F)C([H])=C2[H])C([H])([H])C([H])([H])C([H])([H])C3([H])[H])C([H])([H])C1([H])[H]
[H]OC(=O)C([H])([H])[C@]1([H])N([H])C2=C([H])C([H])=C(C([H])=C2C([H])([H])N(C1=O)C([H])([H])C([H])([H])OC([H])([H])[H])C(=O)N([H])C([H])([H])C1=NC2=C(N1[H])C([H])=C([H])C([H])=C2[H]
[H]O[C@@]1([H])[C@@]([H])(O[C@]([H])(C(=O)N([H])C([H])([H])C([H])([H])[H])[C@@]1([H])O[H])N1C([H])=NC2=C1N=C([H])N=C2N(C(=O)N([H])C1=C([H])C([H])=C(C([H])=C1[H])[N+]([O-])=O)C(=O)N([H])C1=C([H])C([H])=C(C([H])=C1[H])[N+]([O-])=O
[H]N(C(=O)C1=C(N([H])C(=O)C2=C([H])C([H])=C(C([H])=C2[H])C2=C([H])C(N([H])C([H])([H])[H])=C([H])C([H])=C2[H])C([H])=C([H])C(Cl)=C1[H])C1=C([H])C([H])=C(Cl)C([H])=N1
[H]ON([H])C(=O)[C@@]1([H])C([H])([H])N(C(=O)C([H])([H])[H])C([H])([H])C([H])([H])[C@]1([H])C(=O)N([H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])OC1=C2C([H])=C([H])C([H])=C([H])C2=NC([H])=C1[H]
[H]OC1=C([H])C(F)=C([H])C(=C1[H])C1=NC(=NC(N([H])C(=O)C([H])([H])[H])=C1[H])N1N=C(C([H])=C1C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])[C@]1([H])[N@]2C([H])([H])C([H])([H])[C@]([H])(C([H])([H])C2([H])[H])[C@@]1([H])OC([H])([H])C1=C([H])C([H])=C([H])C([H])=C1Cl
[H]OC(=O)[C@]([H])(N([H])C(=O)OC([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(N([H])C(=O)C2=C([H])C(N([H])C(=N[H])N([H])[H])=C([H])C([H])=C2[H])C([H])=C1OC([H])([H])[H]
[H]C1=NC(=C([H])C(OC2=C([H])C([H])=C([H])C3=C2[C@@]([H])(C2=C([H])C([H])=C(SC([H])([H])[H])C([H])=C2[H])C([H])([H])N(C([H])([H])[H])C3([H])[H])=C1[H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]C([H])([H])C([H])([H])OC(=O)N1C([H])([H])C([H])([H])N(C(=O)C([H])([H])C([H])([H])[C@@]([H])(C(=O)N2C([H])([H])C([H])([H])C([H])([H])[C@@]2([H])C#N)[N+]([H])([H])[H])C([H])([H])C1([H])[H]
[H]N(N(C(=O)OC([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C(=O)C1=C2C([H])=C([H])C([H])=C(F)C2=NC(C2=C([H])C([H])=C([H])C([H])=C2[H])=C1C([H])([H])N1C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])C1(C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]OC1=C([H])C([H])=C(C([H])=C1[H])C([H])(N1N=C([H])N=C1[H])C1=C([H])C([H])=C(O[H])C([H])=C1[H]
[H]OC(=O)C1=C([H])C([H])=C(C#CC2=C([H])C3=C(C([H])=C2[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C([H])([H])N3[H])C([H])=C1[H]
[H]C1=C2OC([H])([H])OC2=C([H])C(=C1[H])C1=NN=C(O1)SC([H])([H])C1=C([H])C([H])=C(OC([H])([H])[H])C(F)=C1[H]
[H]N([H])[C@]([H])(C1=C([H])C(=C([H])C([H])=C1N1C([H])([H])C([H])([H])N(C(=O)C([H])([H])OC2=C([H])C([H])=C(OC([H])([H])[H])C([H])=C2[H])C([H])([H])C1([H])[H])C(F)(F)F)C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H]
COC1=CC=C(OC2=C(Cl)C=NN(CC3=CC=CC4=CC=CC=C34)C2=O)C(F)=C1
[H]N1C([H])([H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[C@@]1([H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]N1C([H])=C(C2=C([H])C(F)=C([H])C([H])=C12)C([H])([H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H]
[H]OC([H])([H])[C@@]([H])(C(=O)O[C@@]1([H])C([H])([H])[C@@]2([H])N(C([H])=N[H])[C@]([H])(C([H])([H])C2([H])[H])C1([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C1=C([H])C(=C([H])C([H])=C1C#N)N1C(=O)C2=C([H])C([H])=C(OC([H])(C([H])([H])[H])C([H])([H])[H])N=C2N=C1[C@]([H])(N(C(=O)C([H])([H])C1=C([H])C([H])=C(F)C(=C1[H])C(F)(F)F)C([H])([H])C([H])([H])S(=O)(=O)C([H])([H])C([H])([H])[H])C([H])([H])[H]
[H]C1=C(Cl)C(=NN1C([H])([H])[H])C(=O)N1C([H])([H])C([H])([H])N(C([H])([H])C(=O)C2=C([H])C([H])=C(F)C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N1C(=O)N([H])C2(C3=C([H])C([H])=C([H])C(Br)=C13)C([H])([H])C([H])([H])C2([H])[H]
[H]N1C2=NC([H])=C([H])C([H])=C2N=C(N2C([H])([H])C([H])([H])N(C3=C([H])C(=C([H])C([H])=C3[H])C(F)(F)F)C([H])([H])C2([H])[H])C2=C1C([H])=C([H])C(=C2[H])C([H])([H])[H]
[H]N([H])C(=O)N([H])C1=C([H])C([H])=C2N([H])C(=O)\C(=C(/C3=C([H])C(=C([H])N3[H])C([H])([H])N([H])C(=O)C3=C([H])C([H])=NC([H])=C3[H])C([H])([H])[H])C2=C1[H]
[H]N([H])[C@@]1([H])N=C2N(C([H])=C([H])C([H])=C2C(=O)N1[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC([H])([H])C1=C([H])C([H])=C(Cl)C([H])=C1N([C@]([H])(C([H])([H])[H])C([H])([H])OC(=O)N([H])C([H])([H])C([H])([H])N1C([H])=NC([H])=C1[H])S(=O)(=O)C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]N(C(=O)OC([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)C(=O)OC([H])([H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]C1=C(SC(=C1[H])[C@]1([H])OC2=C(N=NC(SC([H])([H])[H])=N2)C2=C(C([H])=C([H])C([H])=C2[H])N1C(=O)C([H])([H])C([H])([H])[H])C([H])([H])[H]
COC(=O)C1=CC=C2N\C(\C(=N\O)\C2=C1)=C1/C(=O)NC2=C1C=CC=C2
[H]OC(=O)C([H])([H])OC1=C(SC(=C1C([H])([H])[H])C1=C([H])C(OC2([H])C([H])([H])C([H])([H])N(C([H])([H])C2([H])[H])S(=O)(=O)C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])=C([H])C([H])=C1[H])C1=NN([H])N=N1
[H]C([H])=C([H])C([H])([H])N1C2=C(N([H])C(=N2)C2=NN(C(=C2[H])C([H])([H])[H])C([H])([H])[H])C2=N[C@@]([H])(C([H])([H])[H])C([H])([H])N2C1=O
[H]OC(C1=C([H])C([H])=C([H])C([H])=C1[H])(C1=C([H])C([H])=C([H])C([H])=C1[H])[C@@]1([H])C([H])([H])[N@+]2(C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[C@@]1([H])C([H])([H])C2([H])[H]
[H]C1=C([H])C(=C([H])C(=C1[H])C(=O)\N=C1/SC(=C(N1C([H])([H])C1([H])C([H])([H])C1([H])[H])C([H])([H])[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C(F)(F)F
[H]C1=NC(=C([H])C([H])=C1[H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C([H])([H])N1C(=O)N(C(=C(C1=O)C1=C([H])C([H])=C(OC([H])([H])C([H])([H])[H])C([H])=C1[H])C([H])([H])[H])C([H])([H])C1=C(F)C([H])=C([H])C([H])=C1F
[H]N(C(=O)N([H])C([H])([H])C([H])([H])C([H])([H])C(\[H])=C(\[H])C([H])([H])C(\[H])=C(\[H])C([H])([H])C(\[H])=C(\[H])C([H])([H])C(\[H])=C(\[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])F
[H]C(=O)O[C@@]1([H])C(=O)N2C(C(=O)OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])=C(C([H])([H])OC(=O)C([H])([H])[H])C([H])([H])S(=O)(=O)[C@]12[H]
[H]OC(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1=C([H])N=C(S1)C([H])([H])[C@]([H])(N([H])C([H])([H])[C@]([H])(O[H])C([H])([H])OC1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H]
[H]N1C(=O)C([H])=C(C2=C1C([H])=C([H])C(=C2[H])N(C([H])([H])C(F)(F)F)C([H])([H])C(F)(F)F)C([H])([H])[H]
[H]OC([H])([H])[C@@]1([H])O[C@@]([H])(C2=C([H])C([H])=C([H])C(=C2[H])C([H])([H])C2=C([H])C([H])=C(C([H])=C2[H])C([H])([H])[H])[C@]([H])(O[H])[C@@]([H])(O[H])[C@]1([H])O[H]
CN(C)CCN1C(=O)C=CC2=CN=C3C=CC(=CC3=C12)C1=CN=C2C=CC=CC2=C1
[H]N(C(=O)C1=C([H])C([H])=C(C([H])=C1[H])C1=NC2=C([H])C(C#N)=C([H])C(=C2O1)C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])C([H])([H])C([H])([H])N(C2=NC([H])=C(C([H])=C2[H])C2=C([H])C(=C([H])C([H])=C2[H])C([H])([H])[H])C([H])([H])C1([H])[H]
FC1=C(C=C(CC2=NNC(=O)C3=C2C=CC=C3)C=C1)C(=O)N1CCCC1C(=O)N1CCC2=C3C1CNC(=O)C3=CC=C2
[H]OC(=O)C([H])([H])C([H])([H])C([H])([H])SC([H])([H])C([H])([H])N1C(=S)C([H])([H])C([H])([H])[C@]1([H])C(\[H])=C(/[H])[C@@]([H])(O[H])C([H])([H])C1=C([H])C([H])=C([H])C(=C1[H])C([H])([H])[H]
[H]N([H])[C@]([H])(C1=C([H])C(=C([H])C([H])=C1N1C([H])([H])C([H])([H])N(C(=O)C([H])([H])OC2=C([H])C([H])=C([H])C([H])=C2Cl)C([H])([H])C1([H])[H])C(F)(F)F)C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]C1=NN(C([H])=C1C1=NC([H])([H])C2=C1C(OC1([H])C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])=NC([H])=C2[H])[C@@]1([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]O[P@]1(=O)OC([H])([H])[C@]2([H])O[C@@]([H])(N3C([H])=NC4=C(N=C([H])N=C34)N([H])C([H])([H])[H])C([H])([H])[C@]2([H])O[P@@](=O)(O[H])O[P@@](=O)(O[H])O[P@@](=O)(O[H])O1
[H]N(C(=O)N([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C1=C(C([H])=C([H])C([H])=C1C([H])([H])C([H])([H])C([H])([H])C([H])([H])N1C([H])=NC(=C1C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H])N(C([H])([H])[H])C([H])([H])[H]
[H]N1C(=O)C([H])=C([H])C2=C1N=C(OC([H])([H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C3=C(Cl)C(Cl)=C([H])C([H])=C3[H])C([H])([H])C1([H])[H])N=C2[H]
[H]N1C([H])([H])C([H])([H])N(C(=O)[C@]2([H])C3=C([H])C([H])=C([H])C([H])=C3N(C2([H])[H])S(=O)(=O)C2=C([H])C([H])=C(OC([H])([H])[H])C3=C([H])C([H])=C([H])C([H])=C23)C([H])([H])C1([H])[H]
[H]C1=C(OC([H])([H])[H])C([H])=C2OC(=O)C(=C([H])C2=C1[H])C(=O)OC([H])([H])C([H])([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])[C@]([H])(OC1=C([H])C([H])=C(C([H])=C1[H])C(F)(F)F)C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C([H])C([H])=C([H])C([H])=C2OC([H])([H])[H])C([H])([H])C1([H])[H]
[H]N1C(=NC(=C1C1=C([H])C([H])=NC([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C(Br)C([H])=C1[H]
[H]N(C(=O)N([H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])([H])[C@@]3([H])C([H])([H])[C@]2([H])C3(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C(OC(F)(F)F)C([H])=C1[H]
[H]N([H])[C@@]1([H])C([H])([H])C([H])([H])[N@+](C(=O)C([H])([H])[C@@]([H])(N2C(=O)[C@@]([H])(N3C(=O)OC([H])([H])[C@]3([H])C3=C([H])C([H])=C([H])C([H])=C3[H])[C@@]2([H])C(\[H])=C(/[H])C2=C([H])C([H])=C([H])C([H])=C2[H])C(=O)N([H])C([H])([H])C2=C([H])C([H])=C([H])C(=C2[H])C(F)(F)F)(C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C1([H])[H]
[H]C1=C2N(C(=O)C3=C([H])C([H])=C(Cl)C([H])=C3[H])C(=C(C2=C([H])C(OC([H])([H])[H])=C1[H])C([H])([H])C(=O)OC([H])([H])C([H])([H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C([H])([H])[H]
[H]C1=C([H])C([H])=C(C#CC([H])([H])OC2=NSN=C2[C@@]2([H])C([H])([H])[N@]3C([H])([H])[C@]2([H])C([H])([H])C([H])([H])C3([H])[H])C([H])=C1[H]
[H]C1=C2C(=C([H])C(OC([H])([H])[H])=C1[H])C(=O)[C@]([H])(C([H])([H])[H])C2([H])[H]