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[H]OC(=O)C([H])([H])C([H])([H])C1=C([H])C(C2=C(C3=C([H])C(=C([H])C([H])=C3N2[H])C(=N[H])N([H])[H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])=C(OC([H])([H])[H])C(Br)=C1[H]
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[H]C(=C(C1=C([H])C([H])=C(Cl)C([H])=C1[H])C1=C([H])C([H])=C(Cl)C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)C([H])([H])[H]
[H]OC(=O)C1=C([H])C([H])=C([H])C(=C1[H])C1=C([H])C([H])=C(O1)C(\[H])=C1/SC2=NC3=C(C([H])([H])C([H])([H])C4=C([H])C([H])=C([H])C([H])=C34)[C@@]([H])(N2C1=O)C1=C(F)C([H])=C([H])C([H])=C1[H]
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[H]OC1=C([H])C(\C([H])=C2/C(=O)C3=C([H])C([H])=C(OC([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C4=C([H])C([H])=C([H])C(OC(=O)N([H])C([H])([H])[H])=C4[H])C([H])=C3OC2([H])[H])=C([H])C(O[H])=C1O[H]
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[H]N1C(=O)N(C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C([H])([H])SC2=C([H])N(C3=C([H])C([H])=C(Cl)C([H])=C23)C2=C([H])C([H])=C(F)C([H])=C2[H])C([H])([H])C1([H])[H]
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[H]OC([H])([H])C([H])([H])C1=C([H])C(=C([H])C(=C1[H])C(F)(F)F)S(=O)(=O)N1C([H])([H])C([H])([H])N(C(=O)[C@]2([H])C([H])([H])[C@@]2([H])C2=C([H])C([H])=C(C([H])=C2[H])C(F)(F)F)C([H])([H])C1([H])[H]
[H]N(C([H])([H])C1=C([H])SC(=N1)C1=C([H])C([H])=C([H])C([H])=C1[H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
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[H]N([H])C(=NC([H])([H])C([H])([H])C([H])([H])[C@]1([H])N([H])C(=O)[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C(=O)N([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@@]([H])(N([H])C(=O)[C@]([H])(N([H])C1=O)C([H])([H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H])C(=O)N([H])[H])C([H])([H])C1=C([H])N([H])C([H])=N1)C([H])([H])C1=C([H])C([H])=C(I)C([H])=C1[H])N([H])[H]
[H]C1=C([H])C2=C(N=C(SC([H])([H])C#N)N(C2=O)C2([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])=C1C(=O)OC([H])([H])[H]
[H]C([H])=C([H])C([H])([H])OC1=C2C(O[C@]([H])(C3=C2C([H])=C([H])C2=C3C(=C([H])C(N2[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])=C([H])[H])=C([H])C([H])=C1[H]
[H]N(C(=O)C1=C([H])C(F)=C(N([H])C(=O)C([H])([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C(F)=C1[H])C1=NC([H])=C([H])S1
[H]OC1=NC2=C([H])C3=C([H])C(OC([H])([H])C([H])([H])C([H])([H])C(=O)C([H])([H])[H])=C([H])C([H])=C3N([H])C2=N1
[H]C1=C([H])C([H])=C2N(C(=O)OC2=C1[H])C([H])([H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1OC([H])([H])[H]
[H]C1=C([H])C(OC(=O)[C@@]2([H])[C@@]3([H])N(C([H])([H])[H])[C@]([H])(C([H])([H])C3([H])[H])C([H])([H])[C@@]2([H])C2=C([H])C([H])=C(Cl)C([H])=C2[H])=C(C([H])=C1[H])C([H])([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)OC([H])([H])C([H])([H])OC(=O)[C@]1([H])[C@@]2([H])N(C([H])([H])[H])[C@]([H])(C([H])([H])C2([H])[H])C([H])([H])[C@@]1([H])C1=C([H])C([H])=C(Br)C([H])=C1[H]
[H]OC1=C([H])C([H])=C(N([H])C2=NC3=C(C([H])=N2)C([H])([H])C(=O)N([H])C2=C([H])C([H])=C([H])N=C32)C([H])=C1[H]
[H]C1=C([H])C(=C([H])C([H])=C1C(=O)C([H])([H])Br)C([H])([H])[H]
[H]OC(=O)C([H])([H])C([H])([H])C([H])([H])OC1=C(Cl)C([H])=C2N(C(Br)=C(C2=C1[H])C([H])([H])C(=O)N([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]1([H])N(C(=O)[C@@]([H])(N([H])[H])[C@]([H])(O[H])C([H])([H])[H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=N[H])N([H])[H])C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])C([H])([H])C(=O)N([H])[H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=N[H])N([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])[H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=N[H])N([H])[H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=N[H])N([H])[H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=N[H])N([H])[H]
[H]N([H])C(=O)[C@]1([H])C([H])([H])[C@]([H])(N2C([H])=NC(N([H])C(=O)C([H])([H])C3=C4C([H])=C([H])C([H])=C([H])C4=C([H])C([H])=C3[H])=C2[H])C1([H])[H]
[H]N([H])C(=O)C1=C([H])C([H])=C(O[C@]2([H])C([H])([H])[C@@]3([H])N(C([H])([H])C4=C([H])C([H])=C([H])C([H])=C4[H])[C@]([H])(C([H])([H])C3([H])[H])C2([H])[H])C([H])=C1[H]
[H]N1C([H])=C([H])C2=C(C([H])=C([H])C([H])=C12)C(=O)N1C([H])([H])C([H])([H])C([H])(N2C([H])([H])C([H])([H])C([H])(C([H])([H])C3=C([H])C(Cl)=C(Cl)C([H])=C3[H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
CC1=CC=CC=C1SC1=C(C(=O)N2CCNCC2)C2=CC=CC=C2N1C1=CC=CC=C1
[H]OC(=O)C([H])([H])[C@]1([H])N([H])C(=O)C([H])([H])N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)C([H])([H])SC([H])([H])[C@]([H])(N([H])C1=O)C(=O)O[H])[C@@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])N=C(N([H])[H])N([H])[H]
[H]OC([H])([H])[C@@]1([H])O[C@@]([H])(C2=C([H])C(=C(Cl)S2)C([H])([H])C2=C([H])C([H])=C(OC([H])([H])C([H])([H])OC([H])([H])C([H])([H])[H])C([H])=C2[H])[C@]([H])(O[H])[C@@]([H])(O[H])[C@]1([H])O[H]
[H]N([H])C([H])([H])C1=NC([H])=C(C(=O)OC([H])([H])C([H])([H])[H])C2=C1C([H])=C(OC([H])([H])[H])C(OC([H])([H])[H])=C2[H]
[H]N(C(=O)C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C(=O)N(C([H])([H])[H])[C@@]([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
COC1=C(C=CC(NC2=NC=CC(=C2)C2=CC(=CC=C2)C#N)=C1)N1CCOCC1
[H]N1C2=C([H])C(=O)C([H])([H])C([H])([H])[C@]2(C([H])([H])[H])[C@@]2([H])C([H])([H])C([H])([H])[C@]3(C([H])([H])[H])[C@@]([H])(C(=O)C4=C(F)C([H])=C([H])C([H])=C4F)C([H])([H])C([H])([H])[C@]3([H])[C@]2([H])C1([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])OC2=C3C([H])=C([H])C([H])=C([H])C3=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]OC(=O)[C@]([H])(N([H])[H])C([H])([H])[S@](=O)C([H])([H])C([H])([H])N([H])C(=N[H])C([H])([H])[H]
[H]OC1=C([H])C([H])=C(OC([H])([H])C(=O)N([H])[C@@]([H])(C([H])([H])N(C(=O)C([H])([H])[H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2OC([H])([H])[H])C([H])([H])C2=C([H])N([H])C3=C2C([H])=C([H])C([H])=C3[H])C([H])=C1[H]
[H]N(C(=O)C1=NN(C(N2C([H])=C([H])C([H])=C2[H])=C1C([H])([H])[H])C1=C([H])C([H])=C(F)C([H])=C1F)C([H])([H])C1=C(Br)C(OC([H])([H])[H])=C(OC([H])([H])[H])C(OC([H])([H])[H])=C1[H]
[H]N(C(=O)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])[H])C1=C([H])C(=C([H])N([H])C1=O)C1=C([H])C([H])=NC([H])=C1[H]
[H]C1=C([H])C2=C(C([H])=C1[H])C1=C(C([H])=C([H])C([H])=C1[H])C(=O)C([H])([H])N2C(=O)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H]
[H]C1=C(N=C(S1)C1=C([H])C([H])=C(Br)C([H])=C1[H])C1=C([H])N=C([H])C([H])=C1[H]
[H]OC([H])([H])[C@@]1([H])O[C@@]([H])(C2=C([H])C([H])=C(C(=C2[H])C([H])([H])C2=NC([H])=C(S2)C2=C([H])C([H])=C([H])O2)C(F)(F)F)[C@]([H])(O[H])[C@@]([H])(O[H])[C@]1([H])O[H]
[H][C@@]12CC3CC(C3(C)C)[C@]1(C)OB(O2)[C@H](CCCCN)NC(=O)C1=C(C)N=C(C=C1)C1=CC=CC=C1
[H]O[C@@](C1=NC([H])=C([H])S1)(C1=C([H])C([H])=C(C([H])=N1)[C@@]([H])(C1=C([H])C([H])=C(OC([H])(F)F)C(OC([H])(F)F)=C1[H])C([H])([H])C1=C([H])C([H])=[N+]([O-])C([H])=C1[H])C([H])([H])[H]
[H]N(C(=O)[C@]1([H])C(=O)N2C3=C(SC4=C2C([H])=C([H])C([H])=C4[H])C([H])=C([H])C([H])=C13)C1=C([H])C(F)=C([H])C([H])=C1F
CS(=O)(=O)C1=CC(NC2=NC(NC3=C4NC=C(Cl)C4=CC=C3)=CC=N2)=CC=C1
[H]N([H])C1=NC(=C(C(=O)N2C([H])([H])C([H])([H])C(N3C([H])([H])C([H])([H])C([H])(C(=N/OC([H])([H])C([H])([H])[H])\C4=C([H])C([H])=C(Br)C([H])=C4[H])C([H])([H])C3([H])[H])(C([H])([H])[H])C([H])([H])C2([H])[H])C(=N1)C([H])([H])[H])C([H])([H])[H]
[H]N(C1=C([H])C([H])=C(Cl)C([H])=C1[H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])C1(C([H])([H])[H])C([H])([H])C([H])([H])N(C(=O)C2=C(C([H])=C([H])C([H])=C2C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]OC1=C([H])C2=C(C([H])=C1[H])C1=C(C3=C([H])C([H])=C([H])C([H])=C3N1[H])C2([H])[H]
[H]C1=C([H])C(=C([H])C2=C1N(C(=O)\C2=N/C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C([H])([H])[H]
CC(C)(C)OC(=O)N1CCN(CC1)C1=NC=C(OCC2=C(F)C=NC=C2F)C=N1
[H]N1C(=O)N([H])C2(C3=C([H])C(=C([H])C(Cl)=C13)C1=C([H])C([H])=C([H])C([H])=N1)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H]
[H]N(C(=S)N1N=C(C(=C1[H])C1=C([H])N2N=C([H])N=C2C([H])=C1[H])C1=C([H])C([H])=C([H])C(=N1)C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1F
[H]OC1=C2O[C@@]3([H])[C@]([H])(SSC4=C([H])C([H])=C(C([H])=N4)[N+]([O-])=O)C([H])([H])C([H])([H])[C@@]4([H])[C@]5([H])N(C([H])([H])[H])C([H])([H])C([H])([H])[C@]34C2=C(C([H])=C1[H])C5([H])[H]
[H]N(C(=O)N(C([H])([H])[H])S(=O)(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C1=C(C([H])=C([H])C([H])=C1C([H])(C([H])([H])[H])C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]OC(=O)[C@]([H])(N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])N1C(=O)C2=C(C([H])=C3C(=O)N([H])C(=O)C3=C2[H])C1=O
[H]C1=C([H])C2=C(O[C@]([H])(C([H])([H])N3C([H])([H])C([H])([H])N(C4=C(Cl)C(=O)N(N=C4[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N4C([H])([H])C([H])([H])N(C5=C([H])C([H])=C([H])C([H])=C5OC([H])([H])[H])C([H])([H])C4([H])[H])C([H])([H])C3([H])[H])C([H])([H])O2)C([H])=C1[H]
[H]N1C(=O)N(C([H])([H])C([H])([H])N2C([H])([H])C([H])([H])C([H])(C3=C([H])N(C4=C([H])C([H])=C(C([H])=C34)C3=NC([H])=NN3C([H])([H])[H])C3=C([H])C([H])=C(F)C([H])=C3[H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]N(C(=O)N1C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C(=O)N1C([H])([H])C([H])([H])[C@]2([H])N(C3=NC4=C(S3)C([H])=C(F)C([H])=C4[H])C(=O)[C@@]([H])(C([H])([H])[H])[C@@]12[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]C1=NC2=C(C([H])=C1[H])C([H])=C([H])C([H])=C2S(=O)(=O)N(C([H])([H])[H])C([H])([H])[C@]([H])(C1=C([H])C([H])=C(Cl)C(Cl)=C1[H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])[C@]2(C3=C(C([H])=C([H])C([H])=C3[H])[S@](=O)C2([H])[H])C([H])([H])C1([H])[H]
[H]OC(=O)C1=C([H])C(=O)C2=C(Cl)C(OC3=C([H])C(=C(O[H])C([H])=C3[H])C([H])(C([H])([H])[H])C([H])([H])[H])=C(Cl)C([H])=C2N1[H]
[H]OC(=O)C([H])([H])[C@@]1([H])C(=O)C2=C(C([H])=C(N([H])C([H])([H])C([H])([H])C([H])([H])C3([H])C([H])([H])C([H])([H])N([H])C([H])([H])C3([H])[H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N(C(=O)C1=C([H])N=C(N2C([H])([H])C([H])([H])N([C@]([H])(C(=O)OC([H])([H])[H])C2([H])[H])C2([H])C([H])([H])C([H])([H])N(C([H])([H])C3=C([H])C([H])=C(Cl)C([H])=C3[H])C([H])([H])C2([H])[H])C(Cl)=C1[H])C([H])([H])[H]
[H]OC(=O)[C@]1([H])[C@]([H])(N(C([H])([H])C([H])([H])S(=O)(=O)C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])[C@@]1([H])C1=C([H])C2=C(OC([H])([H])O2)C([H])=C1[H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]N(C(=O)[C@]([H])(C1=C([H])C(F)=C(N([H])S(=O)(=O)C([H])([H])[H])C([H])=C1[H])C([H])([H])[H])C([H])([H])C1=C(N=C(C([H])=C1[H])C(F)(F)F)N1C([H])([H])C([H])([H])N(C2=C(C([H])=C([H])C([H])=N2)C(F)(F)F)C([H])([H])C1([H])[H]
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[H][C@@]1(CCCCN1)[C@H](C(N)=O)C1=CC(Cl)=C(Cl)C=C1
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[H]C1=C(Br)C(=NN1C([H])([H])[H])C(=O)N1C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C2=C(F)C([H])=C(F)C([H])=C2[H])C([H])([H])C1([H])[H]
[H]C1=C([H])C2=C(C(OC([H])([H])[H])=C1[H])C([H])([H])N(C(=O)C1=C([H])C(=C([H])C([H])=C1O[C@@]([H])(C([H])([H])[H])C(F)(F)F)S(=O)(=O)C([H])([H])[H])C2([H])[H]
[H]N(C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C([H])C([H])=C(F)C([H])=C2[H])C([H])([H])C1([H])[H])S(=O)(=O)C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]C1=C([H])C(OC2=C([H])C3=C(N=C(N(C3=O)C([H])([H])[C@]3([H])C([H])([H])N(C([H])([H])C([H])([H])C3([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])=C2[H])=C([H])C([H])=C1F
[H]OC(=O)[C@@]1([H])C([H])([H])[C@]1([H])[C@](N([H])[H])(C(=O)O[H])C([H])([H])C1([H])C2=C(OC3=C1C([H])=C([H])C([H])=C3[H])C([H])=C([H])C([H])=C2[H]
[H]OC(=O)C(\[H])=C(/[H])C1=C([H])C([H])=C(SC2=C(Cl)C([H])=C(Cl)C([H])=C2[H])C(Cl)=C1[H]
[H]O[C@@](C#CC1=C([H])C([H])=C([H])C([H])=C1[H])(C1=C([H])N=C([H])N1C([H])([H])[H])C1=C([H])C([H])=C(C#N)C(=C1[H])C1=C([H])C([H])=C([H])C([H])=C1C([H])([H])[H]
[H]N([H])C([H])([H])C1=C(N2N=C(N=C2N=C1C([H])([H])[H])N(C([H])([H])[H])C([H])([H])C([H])([H])OC([H])([H])[H])C1=C(Cl)C([H])=C(Cl)C([H])=C1[H]
[H]N1C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])[C@@]([H])(C1=C([H])N=C([H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1Cl
[H]OC(=O)C1=C([H])C2=C(C([H])=C1[H])N(C(=O)C1=C2N=C(N1C([H])([H])C([H])([H])C1=C(Cl)C([H])=C([H])C([H])=C1[H])N1C([H])([H])C([H])([H])C([H])([H])[C@@]([H])(N([H])[H])C1([H])[H])C([H])([H])[H]
[H]OC(=O)C1=C(N([H])S(=O)(=O)C2=C(N([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H])C([H])=C([H])C([H])=C2[H])C([H])=C([H])C2=C1C([H])([H])C([H])([H])C([H])([H])C2([H])[H]
[H]N([H])C1=C(N(C(=O)C2=C([H])C(=C([H])C([H])=C2[H])N2C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C([H])([H])[H])C(=O)N([H])C(=O)N1C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C1=NC2=C([H])C([H])=C([H])C([H])=C2C(=N1)N1C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]ON([H])C(=O)[C@]([H])(N(C([H])([H])C1=C([H])C2=C(OC([H])([H])O2)C([H])=C1[H])S(=O)(=O)C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])C([H])([H])C([H])([H])C(=O)N([H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]\C(=C(\[H])C1=C([H])C([H])=C(OC([H])([H])[H])C(OC([H])([H])[H])=C1[H])C1=NC2=C(N1C([H])([H])[H])C(=O)N(C(=O)N2C([H])([H])[H])C([H])([H])[H]
[H]N([H])C1=NC2=C(N=NN2C([H])([H])C2=C([H])C([H])=C([H])S2)C(=N1)C1=C([H])C([H])=C([H])O1
[H]N1C(=O)S[C@@]([H])(C1=O)C([H])([H])C1=C([H])C([H])=C(OC([H])([H])C([H])([H])O\N=C(\C2=NC([H])=C(C([H])=C2[H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])[H])C([H])=C1[H]
[H]OC(=O)C1=C([H])C([H])=C([H])C(=C1[H])C([H])([H])OC1=C(Cl)C([H])=C(C([H])=C1[H])C([H])([H])O[H]
[H]C1=C([H])C([H])=C(C([H])=N1)[C@]([H])(C#N)N1C([H])([H])C([H])([H])N(C(=O)C([H])([H])N(C([H])([H])[H])[C@@]([H])(C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N1C([H])([H])C([H])([H])[C@]([H])(C2=C([H])N=C(OC([H])([H])C([H])([H])C([H])([H])OC([H])([H])C3=C(OC([H])([H])[H])C([H])=C([H])C([H])=C3[H])C([H])=C2[H])[C@@]([H])(OC([H])([H])C2=C([H])C(OC([H])([H])[H])=C3C([H])=C([H])C([H])=C([H])C3=C2OC([H])([H])[H])C1([H])[H]
[H]OC(=O)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[C@]([H])(N([H])[H])C(=O)N1C([H])([H])C2=C(C([H])=C([H])C([H])=C2[H])C([H])([H])[C@@]1([H])C1=NC(=C([H])N1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N([H])C([H])([H])C([H])([H])C1=C([H])N([H])C2=C1C([H])=C(OC([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])=C2[H]
[H]ON([H])C(=O)[C@]1([H])N(C([H])([H])C([H])([H])C([H])([H])N([H])C1([H])[H])S(=O)(=O)C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]N(C(=O)C1=C([H])C([H])=C(C([H])=C1[H])N(C([H])([H])[H])C([H])([H])[H])C1=NC([H])=C(SC2=C([H])C(=C([H])C(=C2C([H])([H])[H])C([H])([H])[H])C(=O)N2C([H])([H])C([H])([H])N(C(=O)C([H])([H])[H])C([H])([H])C2([H])[H])S1
[H]OC(=O)C1=C(O[H])C([H])=C([H])C(=C1[H])S(=O)(=O)N([H])C([H])([H])C1=NC([H])=C(C([H])=C1[H])C(=O)N([H])[C@]([H])(C(=O)C1=NC2=C(O1)C(OC([H])([H])[H])=C([H])C([H])=C2[H])C([H])([H])C(=O)O[H]
[H]O[P@@](=O)(C([H])([H])[C@]([H])(C(=O)N([H])[C@@]([H])(C(=O)N([H])[H])C([H])([H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])[C@@]([H])(N([H])C(=O)OC([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC(=O)C([H])([H])C([H])([H])N([H])C(=O)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1N=C(C([H])=C1C1=C([H])C([H])=C(OC(F)(F)F)C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)C([H])([H])[H]
[H]C1=NC(OC([H])([H])[H])=NC([H])=C1C1=C2N=C(N=C(N(C([H])([H])C([H])([H])OC([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])F)N2N=C1C([H])([H])[H])C([H])([H])[H]
[H]C1=C(SC(=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C(=O)C([H])([H])[H])C(=O)C(F)(F)F
[H]C1=C(OC([H])([H])[H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C([H])=C1C([H])([H])C([H])([H])OC(=O)[C@]1([H])N(C(=O)C(=O)C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C1([H])[H]
[H]N1C(SC([H])([H])C2=C(Cl)C([H])=C([H])C([H])=C2Cl)=NC2=C([H])C(F)=C(C([H])=C12)N1C([H])([H])C([H])([H])N([H])C([H])([H])C1([H])[H]
[H]N(C(=O)C([H])([H])[H])C1=NC2=C(OC3=NC(=NC(=C3[H])C3=C([H])C([H])=C(C([H])=C3[H])C(F)(F)F)N([H])[C@@]([H])(C3=C([H])C([H])=C([H])N=C3[H])C([H])([H])[H])C([H])=C([H])C([H])=C2S1
[H]OC1=NC2=C([H])C(Cl)=C([H])C([H])=C2C(OC2([H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C2([H])[H])=C1C1=C([H])C(=C([H])C(=C1[H])C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C(C([H])=C1[H])C1=C(C([H])=C([H])C(=C1[H])C1=NN=C(O1)C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C(OC([H])([H])[H])C(=C1[H])N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N([H])N1C(=S)N([H])N=C1C([H])([H])C1=C([H])C([H])=C(Br)C([H])=C1[H]
[H]C1=C([H])C([H])=C2C(=C1[H])C([H])([H])OC21C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])[C@]2(C3=C([H])C([H])=C(Cl)C(Cl)=C3[H])C([H])([H])N(C(=O)C([H])([H])C3=C([H])C(OC([H])(C([H])([H])[H])C([H])([H])[H])=C([H])C([H])=C3[H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]N(C(=O)C([H])([H])SC1=C(C#N)C([H])=C([H])C(=N1)C1=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C([H])=C1[H])C1=C(C#N)C2=C(S1)C([H])([H])C([H])([H])C2([H])[H]
[H]N1N=NC2=C1C([H])=C([H])C1=C2C([H])([H])[C@]2(C1=C(C(=O)C([H])([H])C2([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N1C([H])([H])C([H])([H])C2=C([H])C(OC([H])([H])[H])=C(Br)C([H])=C2[C@@]([H])(C1([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]OC(=O)C1=C([H])C(=C([H])C([H])=C1[H])C([H])([H])N([H])C(=O)[C@@]1([H])N(C(=O)C([H])([H])[C@@]([H])([N+]([H])([H])[H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(C(=O)C([H])([H])[H])C1=C(N=C(O1)C1=C([H])C(=C([H])N=C1[H])C1=C([H])SC([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N1C(=O)N(C(=O)C2=C([H])C(=C([H])C([H])=C12)C([H])([H])[H])C([H])([H])[C@]([H])(C([H])([H])[H])C([H])([H])N1C([H])=NC([H])=C1[H]
[H]C1=C([H])N(C([H])=N1)C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C(=O)C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)C1=C(F)C([H])=C([H])C([H])=C1Cl)C1=C([H])C([H])=C2N=C(N(C(=O)C2=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C(Cl)=C1[H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]OC(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])O\N=C(\[C@]([H])(N1C([H])=NC([H])=C1[H])C([H])([H])C1=NC([H])=C([H])C([H])=C1[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N=C(N([H])[H])N([H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=O)[C@@]1([H])N2C(=O)[C@@]([H])(N([H])S(=O)(=O)C([H])([H])C3=C([H])C([H])=C([H])C([H])=C3[H])C([H])([H])C([H])([H])[C@]2([H])SC1([H])[H]
[H]OC(=O)C([H])([H])C1=C([H])C(Cl)=C(OC2=C([H])C(Br)=C(O[H])C([H])=C2[H])C(Cl)=C1[H]
[H]OC1=C(C([H])=C(C([H])=C1Br)[N+]([O-])=O)C1=C([H])C2=C([H])C(=C([H])C([H])=C2N1[H])C(=N[H])N([H])[H]
[H]OC1=C(OC([H])([H])[H])C([H])=C(\C([H])=C(/[H])C(=O)N2C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])=C1[H]
[H]OC(=O)C([H])([H])[C@@]1([H])C2=C([H])C([H])=C(OC([H])([H])C([H])([H])C([H])([H])OC3=C([H])C(=C([H])C([H])=C3[H])C([H])([H])[H])C([H])=C2C([H])([H])C1([H])[H]
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[H]N1C(=NN2N=C([H])C3=C2C(Cl)=C([H])C([H])=C3[H])N([H])C([H])([H])C1([H])[H]
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[H]N([H])C1=C(C([H])=NN1C([H])([H])[H])C1=C([H])C2=C(OC([H])([H])C([H])([H])N2C2=NC3=C(S2)C(=O)N([H])C(C([H])([H])[H])(C([H])([H])[H])C3([H])[H])C([H])=C1[H]
[H]OC1=C([H])C([H])=C([H])C(C#CC2=C(C([H])=C([H])C(C#N)=C2[H])C([H])([H])O[C@]([H])(C2=C([H])N=C([H])N2C([H])([H])[H])C2=C([H])C([H])=C(C#N)C([H])=C2[H])=C1[H]
[H]N1C([H])([H])C2=C([H])C([H])=C(C([H])=C2[H])C([H])([H])N([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C(=O)N(C([H])([H])C2=C(OC([H])([H])[H])C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N(C(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1OC([H])([H])[H]
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[H]N(C1=NC2=C(C([H])=N1)C([H])=C([H])C(OC([H])([H])[H])=C2C([H])(C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N([C@]1([H])C([H])([H])OC([H])([H])[C@]1([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C(C#N)C([H])=C1[H])S(=O)(=O)C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C2=C(C(OC([H])([H])[H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C([H])([H])[C@@]1([H])C2=C([H])C([H])=C([H])C([H])=C2C([H])([H])C([H])([H])C1([H])[H]
[H]OC1=C([H])C([H])=C(C([H])=C1[H])C1=NC2=C([H])C(O[H])=C([H])C(C(=O)OC([H])([H])C([H])([H])[H])=C2O1
[H]OC1=C2C([H])=C(N(C2=C([H])C([H])=C1[H])C([H])([H])C1=C([H])C(=C([H])C([H])=C1[H])C(=N[H])N([H])[H])C(=O)N([H])C([H])([H])C1=C([H])C(N([H])C(=O)N([H])[H])=C([H])C([H])=C1[H]
[H]N([H])C1=NC(=C(C(=N1)N([H])[H])C1=C([H])C([H])=C(N([H])C(=O)C([H])([H])C2=C(Br)SC([H])=C2[H])C([H])=C1[H])C([H])([H])OC([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC1=C(C([H])=C(Cl)C(N([H])[H])=C1[H])C(=O)N([H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H]
[H]N([H])[C@@]1([H])C([H])([H])N(C2=NC([H])=C(\C([H])=C(/[H])C3=C([H])C([H])=C([H])C([H])=C3[H])C(=O)N2C([H])([H])C2=C(C#N)C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C1([H])[H]
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[H]N(C(=O)C1=C([H])C(OC([H])([H])[H])=C([H])C([H])=C1[H])C1=NN([H])C(=C1[H])C1([H])C([H])([H])C1([H])[H]
[H]N1C([H])([H])[C@@]2([H])C([H])([H])N(C3=C([H])C([H])=C(C([H])=C3[H])C3=C([H])C([H])=C([H])C([H])=C3[H])C([H])([H])[C@@]2([H])C1([H])[H]
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[H]\C(=C(\[H])C([H])([H])N1C([H])([H])C([H])([H])N(C(=O)C2=C([H])SC(=C2[H])C([H])([H])[H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C1=C2N=C([H])C([H])=C(N2N=C1C1=C([H])C(OC([H])([H])[H])=C([H])C(OC([H])([H])[H])=C1[H])C1=C([H])C(OC([H])([H])C2([H])C([H])([H])C2([H])[H])=C(OC([H])(F)F)C([H])=C1[H]
[H]O[C@]([H])(C([H])([H])OC1=C([H])C([H])=C([H])C2=C1C([H])=C([H])N2[H])C([H])([H])N1C([H])([H])C([H])([H])C([H])(C2=C([H])C3=C(S2)C([H])=C([H])C([H])=C3C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N(C1=C([H])N=C([H])C(=N1)C1=C([H])C(N([H])C([H])([H])C([H])([H])C([H])([H])N2C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])=C([H])N=C1[H])C1=C([H])C(Cl)=C([H])C([H])=C1[H]
[H]N(C1=C(C([H])=C([H])C([H])=C1[H])C(=O)N1C([H])([H])C([H])([H])C([H])(N2C([H])([H])C([H])([H])C([H])(C([H])([H])C2([H])[H])C2(OC([H])([H])C([H])([H])O2)C2=C([H])C([H])=C(C([H])=C2[H])S(=O)(=O)C2=C([H])C([H])=C(OC([H])([H])[H])C([H])=C2[H])C([H])([H])C1([H])[H])C([H])([H])[H]
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[H]\C(=C(/[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@]([H])(C(=O)C1=NC2=C(O1)N=C([H])C([H])=C2[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]OC1=C(C2=C(N=C(O2)C2=C(N=C([H])C(=C2[H])C2=C([H])N(N=C2[H])C2([H])C([H])([H])C([H])([H])N([H])C([H])([H])C2([H])[H])N([H])[H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]\C(=C(/C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])C([H])([H])[H])C([H])([H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
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[H]N([H])C(=O)C1=NN(C2=C1C([H])([H])C([H])([H])C1=C([H])N=C(N=C21)N([H])C1=C(OC(F)(F)F)C([H])=C([H])C(N([H])C(=O)[C@@]2([H])N([H])C([H])([H])C([H])([H])C2([H])[H])=C1[H])C([H])([H])[H]
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[H]C1=NC(=C([H])C([H])=C1[H])C1=NC(=C([H])C(=N1)N(C([H])([H])[H])C([H])([H])[H])C(F)(F)F
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[H]C1=NC(=NC([H])=C1[H])N1C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])OC2=C([H])C([H])=C([H])C([H])=C2C([H])([H])C([H])([H])C2=C([H])C([H])=C([H])C(OC([H])([H])[H])=C2[H])C([H])([H])C1([H])[H]
[H]N(C(=O)N1C2=C(C([H])=C(OC([H])([H])[H])C(=C2[H])C(F)(F)F)C([H])([H])C1([H])[H])C1=C([H])C(=C([H])N=C1[H])C1=C(C([H])=C([H])N=C1[H])C([H])([H])[H]
[H]N([H])C1=C(N=C(N=C1N([H])C([H])([H])C1=NN=NN1[H])C#N)N([H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])C2=C(N=C1N1C([H])([H])C([H])([H])N(C([H])([H])[C@]3([H])OC4=C5C([H])=C([H])C(=NC5=C([H])C([H])=C4OC3([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H])C([H])=C([H])C(=C2[H])[N+]([O-])=O
[H]OC(=O)C1=C([H])C([H])=C([H])C(=C1[H])S(=O)(=O)N1C([H])([H])C2=C(C([H])=C([H])C(C#CC3=C([H])C([H])=C(OC(F)(F)F)C([H])=C3[H])=C2[H])C([H])([H])C1([H])[H]
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[H]N(C1=C([H])C([H])=C2C(=C1[H])C([H])([H])C([H])([H])N(C([H])([H])[C@@]1([H])C([H])([H])OC([H])([H])C1([H])[H])C([H])([H])C2([H])[H])S(=O)(=O)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]N(C(=O)C1=C([H])OC(=C1[H])C1=C([H])C(=C([H])C([H])=C1C([H])([H])[H])C([H])([H])[H])C1=C(C([H])=C([H])C([H])=C1C([H])([H])[H])C([H])([H])[H]
[H]N([H])[C@@]1([H])C([H])([H])C([H])([H])[C@]([H])(N([H])C2=NC3=C([H])C([H])=NN3C(N([H])C3=C([H])C([H])=C(C([H])=C3[H])C(=O)OC([H])([H])C([H])([H])[H])=C2C([H])([H])[H])C([H])([H])C1([H])[H]
[H]ON(C(=O)[C@]([H])(C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N([H])C([H])([H])C1=C(C([H])=C([H])C([H])=C1[H])N1N=C(C([H])=C1C(=O)N([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1S(=O)(=O)N([H])[H])C(F)(F)F
[H]OC(=O)C([H])([H])C([H])([H])N([H])C(=O)[C@]([H])(C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[C@@]([H])(S[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)[C@]([H])(C1=C([H])C([H])=C(N([H])S(=O)(=O)C([H])([H])[H])C(F)=C1[H])C([H])([H])[H])C([H])([H])C(\[H])=C(/[H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]N(C1=NC([H])=NC2=C1N=NN2C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N([H])C1=C([H])C2=C(OC3=NC([H])=NC(N([H])C4=C([H])C([H])=C(F)C(Cl)=C4[H])=C3N([H])C2([H])[H])C([H])=C1[H]
[H]N(C(=O)C1=C([H])SC(=N1)N([H])C1=C(C([H])=C([H])C([H])=C1Cl)C(F)(F)F)C1=C([H])C([H])=C(C([H])=C1[H])C(F)(F)F
[H]N([H])C([H])([H])C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]N1C(=O)N([H])C(=O)C(N2C([H])([H])C([H])([H])N(C3=C([H])C([H])=C(C([H])=C3[H])[N+]([O-])=O)C([H])([H])C2([H])[H])(C1=O)C1=C([H])C([H])=C(OC2=C([H])C([H])=C(Br)C([H])=C2[H])C([H])=C1[H]
[H]OC([H])([H])[C@@]1(OC(=O)\C(=C(\[H])C2=C([H])C(=C([H])C(=C2[H])C(F)(F)F)C(F)(F)F)C1([H])[H])C([H])([H])OC(=O)C([H])([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
COC(=O)C(N1C(C2=CC=C(Cl)C=C2)C(=S)NC2=CC=C(Cl)C=C2C1=O)C1=CC=C(Cl)C=C1
[H]C1=C([H])C(=C([H])C([H])=C1OC([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C([H])([H])[H])C(=O)C([H])([H])N1C([H])([H])C([H])([H])N(C(=O)OC([H])([H])[H])C([H])([H])C1([H])[H]
[H]N1C(=O)N([H])[C@](C1=O)(C1=C([H])C([H])=C(F)C([H])=C1[H])C([H])([H])N1C(=O)C2=C(C([H])=C([H])C([H])=C2[H])C1([H])[H]
[H]N(C(=O)N(C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H])[C@]1([H])C([H])([H])C([H])([H])[C@]2(C3=C([H])C([H])=C(F)C(F)=C3[H])C([H])([H])[C@]12[H])C1=C([H])C([H])=C(F)C(Cl)=C1[H]
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[H]N(C(=O)C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C(=O)N([H])[C@]([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]N([H])S(=O)(=O)C1=NN=C(S1)N([H])S(=O)(=O)C1=C([H])C([H])=C(N([H])C([H])([H])C2=C([H])C(=O)OC3=C2C([H])=C([H])C(Cl)=C3[H])C([H])=C1[H]
[H]N([H])C1=NC(=NC(=N1)C([H])([H])[H])C1=C(N=C2C([H])=C([H])C(=C([H])N12)C1=C(C([H])=C([H])N=C1[H])C([H])([H])[H])N([H])C1=NN([H])C([H])=C1[H]
[H]OC(=O)C([H])([H])C([H])([H])C(=N\OC([H])([H])C([H])([H])C([H])([H])C([H])([H])O\N=C(\C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])C([H])([H])[H])\C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N([H])[C@]([H])(C1=C(C([H])=C([H])C(=C1[H])C([H])([H])[H])N1C([H])([H])C([H])([H])N(C(=O)[C@]2([H])C([H])([H])N(C([H])([H])[C@@]2([H])C2=C([H])C([H])=C(Cl)C([H])=C2[H])[C@]([H])(C([H])([H])[H])C([H])([H])OC([H])([H])[H])C([H])([H])C1([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)C([H])([H])N1C(=O)C2=C([H])C([H])=C([H])N2C2=C(C([H])=C([H])N=C12)C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C([H])C([H])=C(C([H])=C2[H])C([H])([H])[H])C([H])([H])C1([H])[H]
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[H]C([H])(N1C([H])([H])C([H])([H])C([H])(C([H])([H])OC2=C(F)C(F)=C(F)C(F)=C2F)C([H])([H])C1([H])[H])C1=C(F)C(F)=C(F)C(F)=C1F
[H]N1C([H])=C(\C([H])=C2/N([H])C(=S)N([H])C2=O)C2=C1C([H])=C([H])C(Br)=C2[H]
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[H]N(C(=O)C1=C([H])C2=C(N=C([H])C([H])=C2[H])C([H])=C1[H])[C@@]([H])(C(=O)N1C([H])([H])C([H])([H])N(C2=C(C([H])=C([H])C([H])=C2[H])N(C([H])([H])C2([H])C([H])([H])C2([H])[H])S(=O)(=O)C([H])([H])[H])C([H])([H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]ON([H])C(=O)[C@@]([H])(O[H])C([H])([H])N(C1=C([H])C([H])=C(OC2=C([H])C([H])=C(C([H])=C2[H])C([H])([H])[H])C([H])=C1[H])S(=O)(=O)C([H])(C([H])([H])[H])C([H])([H])[H]
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[H]OC(=O)C([H])([H])C1=C([H])N(N=C1C1=C([H])C([H])=C(C#CC2=C([H])C([H])=C(Cl)C([H])=C2[H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C1=NC(=C(O1)C1=NN=C(SC([H])([H])C([H])([H])C([H])([H])N2C([H])([H])C3([H])C([H])([H])C3(C3=C([H])C([H])=C(C([H])=C3[H])S(F)(F)(F)(F)F)C2([H])[H])N1C([H])([H])[H])C([H])([H])[H]
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[H]OC(=O)C([H])([H])OC1=C([H])C(C(=O)N([H])C2=C([H])C([H])=C(Cl)C([H])=N2)=C(N([H])C(=O)C2=C([H])C([H])=C(C([H])=C2[H])C(=N[H])N(C([H])([H])[H])C([H])([H])[H])C([H])=C1[H]
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[H]OC1=NSC(N([H])C2=C([H])C([H])=C(Cl)C([H])=C2[H])=C1C#N
[H]C1=C([H])C(=C2N(C3=NC4=C([H])C([H])=C([H])C([H])=C4N=C3C2=C1[H])C([H])([H])[H])C([H])([H])[H]
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[H]OC(=O)C1=C(N([H])C(=O)N2C([H])([H])C([H])([H])N(C3=NC4=C([H])C(O[H])=C([H])C([H])=C4N=C3[H])C([H])([H])C2([H])[H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C(=NN1C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C(Cl)C([H])=C([H])C([H])=C1[H]
[H]C1=C([H])C2=C(C([H])=C1[H])C([H])=C(C1=C(O2)C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])([H])N(C([H])([H])C([H])([H])[H])C([H])([H])C1([H])[H]
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[H]OC1=C([H])C([H])=C([H])C(=C1[H])C([H])([H])N1C([H])([H])C([H])([H])C([H])(C([H])([H])C([H])([H])C(=O)C2=C([H])C3=C4N(C([H])=C([H])C4=C2[H])C(=O)C([H])([H])C3([H])[H])C([H])([H])C1([H])[H]
[H]N(C1=C([H])C([H])=C(OC(F)(F)F)C([H])=C1[H])C([H])([H])[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@]1([H])C([H])([H])OC([H])([H])C1([H])[H])C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])[H]
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[H]O[C@]([H])(C([H])([H])N(C1=C([H])C(OC2=C([H])C([H])=C([H])C([H])=C2[H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])C(OC(F)(F)F)=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]OC(=O)C(=C(/[H])C1=C(OC2=C([H])C([H])=C(F)C(F)=C2[H])C2=C([H])C(OC([H])([H])C3=C([H])C([H])=C(C([H])=C3[H])C3=C([H])C([H])=C([H])C([H])=C3[H])=C(OC([H])([H])C3=C([H])C([H])=C(C([H])=C3[H])C3=C([H])C([H])=C([H])C([H])=C3[H])C([H])=C2S1)\C1=C([H])C([H])=NC([H])=C1[H]
[H]N(C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1C([H])([H])C([H])([H])O[C@@]([H])(C2=C([H])C([H])=C([H])C([H])=C2[H])C1([H])[H]
[H]N(C1=NC([H])=NC2=C1N=C([H])N2[H])C1=C([H])C(=C([H])C([H])=C1[H])C1=NC2=C(S1)C([H])=C([H])C([H])=C2[H]
[H]C1=C(SC(=C1[H])C1=NC(=NO1)C1=C([H])C([H])=C([H])N=C1[H])C(=O)C(F)(F)F
[H]C1=C(N2N=NC3=C2N=C(N=C3N(C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])[H])C(Br)=C([H])C(=C1[H])C([H])(C([H])([H])[H])C([H])([H])[H]
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[H]OC(=O)C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1OC([H])([H])C([H])([H])[C@@]1([H])OC2=C([H])C([H])=C([H])C([H])=C2N(C1=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C(O[H])(C([H])([H])[H])C([H])([H])[H]
[H]OC(=O)[C@@]([H])(N([H])C(=O)C([H])([H])N([H])C(=O)C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)N([H])[H])C([H])([H])C(=O)N([H])[H]
[H]OC(=O)C([H])([H])C([H])([H])[C@]([H])(N([H])C(=O)C1=NN(C(OC([H])([H])C(=O)N2C([H])([H])C([H])([H])C([H])([H])[C@@]2([H])C(=O)N([H])C2([H])C([H])([H])C([H])([H])C2([H])[H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C(=O)N1C([H])([H])C([H])([H])N(C2=C([H])C([H])=C([H])C(OC([H])([H])[H])=C2[H])C([H])([H])C1([H])[H]
[H]C1=C([H])C([H])=C2N(C(=NC2=C1[H])N1C([H])([H])C([H])([H])[C@]([H])(N(C([H])([H])[H])C([H])([H])[H])C1([H])[H])C([H])([H])C([H])([H])OC([H])([H])C([H])([H])[H]
[H]N(C1=NC2=C(N=NN2C2=C1C([H])=C([H])C([H])=C2[H])S(=O)(=O)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H])[C@@]([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H]
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[H]N(C(=O)N1C([H])([H])C([H])([H])SC([H])([H])C1([H])[H])C1=C([H])C2=C(N=C(C3=C([H])C([H])=C([H])O3)C(=N2)C2=C([H])C([H])=C([H])O2)C([H])=C1[H]
[H]N(C([H])([H])C([H])([H])OC1=C(C([H])=C([H])C([H])=C1[H])C([H])([H])[H])C([H])([H])[C@@]1([H])OC(OC1([H])[H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC1=NSC(N([H])C2=C(Cl)C(Cl)=C([H])C([H])=C2[H])=C1\C(=N\[C@@]([H])(C([H])([H])[H])C([H])([H])O[H])N([H])[H]
[H]N=C(N([H])[H])C1=C([H])C([H])=C(N([H])C(=O)N([H])C([H])([H])C(=O)N([H])[C@]([H])(C2=C([H])C([H])=C(N3C([H])([H])C([H])([H])OC([H])([H])C3([H])[H])C(=C2[H])C(F)(F)F)C([H])([H])[H])C([H])=C1[H]
[H]N([H])C1=C([H])C([H])=C([H])C2=C1C1=C3C(=C([H])C(OC([H])([H])[H])=C1[H])C([H])([H])C([H])([H])N(C([H])([H])[H])[C@]3([H])C2([H])[H]
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[H]C1=C([H])C(=C([H])C(Cl)=C1Cl)C(=O)N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]N(C1=NC(=O)N(C2=C1C([H])=C(Cl)C([H])=C2[H])C([H])([H])C(F)(F)F)C1([H])C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C3C([H])=C([H])C([H])=C([H])C3=C2[H])C([H])([H])C1([H])[H]
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COC1=CC2=NC=CC(OC3=CC=C(NC(=O)NC4=CC=C(F)C=C4F)C(C)=C3)=C2C=C1OC
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[H]N([H])C1=NC([H])=C(Cl)N=C1C([H])([H])N([H])C(=S)N([H])C1=C([H])C([H])=C([H])C([H])=C1OC([H])([H])[H]
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