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[H]N(C(=O)C1=C([H])C([H])=C([H])C(=C1[H])C(F)(F)F)C([H])([H])C(=O)N([H])[C@]([H])(C(=O)N([H])C1([H])C([H])([H])C1([H])[H])C([H])([H])N([H])C([H])([H])C1=C(C([H])=C(C([H])=C1[H])C([H])([H])[H])C([H])([H])[H]
[H]N(C1=C(C2=NC3=C(C([H])=C(C([H])=C3N2[H])N2C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])C([H])([H])[H])C(=O)N([H])C([H])=C1[H])C([H])([H])C([H])([H])N1N=C(C(Br)=C1[H])C([H])([H])[H]
[H]N(C1=C([H])C([H])=C(F)C(=C1[H])C(F)(F)F)C1=C(C#N)C([H])=NC2=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C([H])=C12
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[H]OP(=O)(O[H])C([H])(C([H])([H])C([H])([H])C([H])([H])C([H])=C(C([H])([H])[H])C([H])([H])[H])P(=O)(O[H])O[H]
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[H]N([C@]1([H])C([H])([H])C([H])([H])[C@](C(=O)N2C([H])([H])[C@@]3([H])N(C(=O)C4=C([H])C([H])=C([H])C([H])=C4[H])C([H])([H])[C@]2([H])C3([H])[H])(C1([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])[C@@]1([H])C([H])([H])C([H])([H])OC([H])([H])[C@@]1([H])F
[H]OC(=O)C1=C([H])[C@]2(C([H])([H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1N(C(=O)C1=C([H])C(OC([H])([H])[H])=C(N([H])C(=O)C3=C([H])C(F)=C([H])C([H])=C3Cl)C([H])=C1[H])C([H])([H])C2([H])[H]
[H]C1=C([H])C(=C([H])C([H])=C1Cl)N1C(=NC(C2=NN=C(O2)C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])=C1C([H])([H])C([H])([H])[H])C1=C([H])C([H])=C(Cl)C([H])=C1Cl
[H]C1=C([H])C([H])=C(C([H])=C1[H])N1C(=O)N(C(=O)C1([H])[H])S(=O)(=O)C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)N(C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H])[C@@]1([H])C([H])([H])C2=C(C([H])=C([H])C(=C2[H])S(=O)(=O)N(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H])C1=C([H])C(Cl)=C(F)C([H])=C1[H]
[H]N([H])C1=C(N=C(C([H])=N1)C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C(=O)N([H])C1=C([H])C([H])=C([H])N=C1[H]
[H]N([H])C1=C([H])C([H])=C([H])C(=C1[H])C1=C([H])N=C2N([H])C([H])=C(C2=C1[H])C1=C([H])C([H])=C([H])N=C1[H]
[H]N(C(=O)C1=C([H])C([H])=C(C#N)C([H])=C1[H])C1=NC2=C([H])C(=C([H])C([H])=C2N1C([H])([H])C([H])([H])C(=O)N(C([H])([H])[H])C([H])([H])[H])N(C(=O)C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])[H]
[H]N([H])C1=C(C([H])=C([H])C(Cl)=N1)C(=O)N1C([H])([H])C([H])([H])C([H])(N2C([H])([H])C([H])([H])N(C3=NC([H])=C(N=C3C(F)(F)F)C(=O)N([H])C3([H])C([H])([H])C3([H])[H])C([H])([H])[C@]2([H])C([H])([H])C([H])([H])[H])C([H])([H])C1([H])[H]
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[H]C1=C([H])N(C(=N1)[S@](=O)C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1N(C([H])([H])[H])C([H])([H])[H])C1=NC([H])=C(C([H])=C1[H])C(F)(F)F
[H]N(C(=O)C1=C([H])C([H])=C([H])C(OC([H])([H])[H])=C1[H])C([H])([H])C1=C(N(C2=C([H])C([H])=C([H])C([H])=C2[H])C2=C([H])C(Cl)=C([H])C([H])=C2C1=O)C(=O)OC([H])([H])[H]
[H]N(C(=O)C([H])([H])C(N([H])C([H])([H])C(=O)N1C([H])([H])[C@@]([H])(F)C([H])([H])[C@@]1([H])C#N)(C([H])([H])[H])C([H])([H])[H])[C@@]1([H])C([H])([H])[C@]1([H])C1=C([H])C(OC(F)(F)F)=C([H])C([H])=C1[H]
[H]C1=C([H])C2=C(C([H])=C([H])C([H])=C2C(C#N)=C1[H])[C@]1([H])C([H])([H])[C@@]1([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H]
[H]OC(=O)C([H])([H])C([H])([H])[C@]([H])(N([H])C(=O)C1=NC(=C([H])C(=C1[H])N(C([H])([H])[H])C([H])([H])C([H])([H])S(=O)(=O)C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C(=O)N1C([H])([H])C([H])([H])N(C(=O)OC([H])([H])C([H])([H])C2([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]OC(=O)[C@]1([H])N([H])C2=C([H])C(Cl)=C([H])C(Cl)=C2[C@]([H])(N([H])C(=O)C2=C([H])C([H])=C([H])C([H])=C2[H])C1([H])[H]
[H]N([H])C(=O)C([H])([H])N1C([H])([H])C([H])([H])C([H])(C2=C([H])C(OC([H])([H])[H])=C(N([H])C3=NN4C(=C([H])C(Cl)=C4C([H])=N3)C3=C([H])C([H])=C([H])C([H])=C3N(C([H])([H])[H])S(=O)(=O)C([H])([H])[H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]OC(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(C([H])([H])[C@@]1([H])ON=C(C2=C([H])C([H])=C([H])C([H])=C2[H])C1([H])[H])C([H])([H])[P@@](=O)(O[H])[C@@]([H])(N([H])C(=O)OC([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H]
[H]N([H])C(=O)[C@]([H])(N([H])C(=O)C1=C2C([H])=C([H])C([H])=C([H])C2=NC(=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N([H])C(=O)C1=NN(C2=C1C([H])([H])C([H])([H])N(C2=O)C1([H])C([H])([H])C([H])([H])N(C2=C([H])C([H])=C([H])C([H])=C2C([H])([H])N(C(=O)C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]N([H])SC([H])([H])N([H])\N=C(/C(/[H])=C(\[H])C1=C([H])C([H])=C([H])C([H])=C1[H])\C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]C1=C([H])C(C2=C3N=C(C([H])=C(N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C3=NN2C([H])([H])C([H])([H])[H])C([H])([H])[H])=C(Cl)C([H])=C1Cl
[H]N(C1=C([H])C(=NN1[H])C([H])([H])[H])C1=NN(C(=O)C2=C1C([H])=C([H])C([H])=C2[H])C([H])([H])[C@]1([H])C([H])([H])N([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(C(=O)C([H])([H])N1C([H])([H])C([H])([H])C2=C(C([H])=C(OC([H])([H])[H])C(OC([H])([H])[H])=C2[H])[C@]1([H])C([H])([H])C1=C([H])C([H])=C([H])C(OC([H])([H])[H])=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N1C([H])([H])C([H])([H])C2=C(C(=NC(=N2)C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C2=C([H])C([H])=C(C([H])=C2[H])C(F)(F)F)C([H])([H])C1([H])[H]
[H]N(C(=O)OC([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)[C@]1([H])O[C@]1([H])C(=O)OC([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC([H])([H])C([H])([H])C([H])([H])O\N=C(/C([H])([H])N(C(=O)C1=C([H])C(Cl)=C([H])C(Cl)=C1[H])C([H])([H])[H])[C@@]([H])(C1=C([H])C([H])=C(Cl)C(Cl)=C1[H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])(N2C(=O)C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]C1=C([H])C2=C(N=C(O2)C([H])([H])SC2=NC3=C([H])C([H])=C([H])C([H])=C3C3=NC(=NN23)C([H])([H])[H])C([H])=C1[H]
[H]C1=C([H])C(OC([H])([H])[H])=C(C([H])=C1[H])N1C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C(OC([H])([H])C([H])([H])F)C(OC([H])([H])[H])=C2[H])C([H])([H])C1([H])[H]
[H]N1C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])[C@]([H])(C1=C([H])C([H])=C([H])C([H])=C1OC([H])([H])[H])C([H])([H])OC([H])([H])C1=C([H])C(=C([H])C(=C1[H])C(F)(F)F)C(F)(F)F
[H]OC1=NSC(N([H])C2=C([H])C([H])=C(C([H])=C2[H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])=C1\C(=N\[C@]([H])(C([H])([H])[H])C([H])([H])O[H])N([H])[H]
[H]OC1=C([H])C([H])=C2N([H])C3=C(C2=C1[H])C1=C(C(=O)N([H])C1=O)C(=C3[H])C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)C([H])([H])[H]
[H]C1=C([H])C([H])=C(N2C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])N3C(=O)[C@]4([H])[C@]([H])(C3=O)[C@]3(OC(=O)C([H])([H])[H])C([H])=C(C([H])([H])[H])[C@@]4([H])[C@]([H])(C([H])([H])[H])C3([H])[H])C([H])([H])C2([H])[H])C(OC([H])([H])[H])=C1[H]
[H]N(C1=NC([H])=NC2=C1C([H])=NN2\C([H])=C(\[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]O[C@@]1([H])C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])N1N=C(N(C1=O)C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1C1=NN([H])N=N1)C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]N(C1=C(C([H])=NC2=C(OC3=NC([H])=C([H])C([H])=C3[H])C([H])=C([H])C([H])=C12)C(=O)C([H])([H])C([H])([H])[H])C1=C(C([H])=C([H])C([H])=C1C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])C2=C(S1)C([H])([H])[C@@]([H])(O[C@]21C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H])C(=O)OC([H])([H])[H]
[H]OC(C(=O)OC([H])([H])C#CC([H])([H])N1C([H])([H])[C@]2([H])C([H])([H])[C@]2([H])C1([H])[H])(C1=C([H])C([H])=C(F)C([H])=C1[H])C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]ON([H])C(=O)C1(C([H])([H])C([H])([H])N([H])C([H])([H])C1([H])[H])S(=O)(=O)C1=C([H])C([H])=C(OC2=C([H])C([H])=C(OC(F)(F)F)C([H])=C2[H])C([H])=C1[H]
[H]N([H])C1=NC2=C(S1)C([H])([H])[C@@]([H])(N(C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[C@@]1([H])C([H])([H])C([H])([H])[C@]([H])(N([H])S(=O)(=O)C3=C([H])C([H])=C(Cl)C([H])=C3[H])C([H])([H])C1([H])[H])C([H])([H])C2([H])[H]
OC(=O)C1=C(CCCOC2=CC=CC3=CC=CC=C23)C2=CC=CC=C2O1
[H]C1=C([H])C(=C([H])O1)C(=O)O[C@@]1([H])[C@]([H])(OC(=O)C([H])([H])[H])[C@]([H])(OC(=O)C([H])([H])[H])[C@@]([H])(C([H])([H])[H])[C@@]23OC(C([H])([H])[H])(C([H])([H])[H])[C@@]([H])(C2([H])[H])C([H])([H])[C@]([H])(OC(=O)C2=C([H])C([H])=C([H])C([H])=C2[H])[C@]13C([H])([H])[H]
[H]O[C@]1(C(=O)N([H])C2=C1C([H])=C(Br)C([H])=C2[H])C([H])([H])C(=O)C1=C([H])C(N([H])S(=O)(=O)C([H])([H])[H])=C([H])C([H])=C1[H]
[H]C1=C(N=C(S1)C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C2C([H])=C(C([H])=C([H])C2=N1)C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C([H])([H])[H]
[H]N([H])C1=NC(=NC(=N1)C([H])([H])[H])C1=C([H])C(=C([H])N=C1N([H])C1=C([H])C([H])=C(OC([H])([H])[H])N=C1[H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
CN1C=C(C(C)=N1)C1=CC=C(CN2C(=O)C3(CCN(C3)C3CCCC3)C3=C2C=CC=C3)C(F)=C1
[H]OC1=C2C([H])=C(C3=C([H])N=C([H])O3)C(OC([H])([H])[H])=C([H])C2=NC(=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C1=NC([H])([H])C([H])([H])N1[H])C1=C2C(=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H]
[H]OC(C#C[C@@]1(OC([H])([H])[H])C([H])([H])[N@]2C([H])([H])C([H])([H])[C@]1([H])C([H])([H])C2([H])[H])(C1=C([H])SC([H])=C1[H])C1=C([H])SC([H])=C1[H]
[H]OC(=O)C1=C([H])C(=C([H])C([H])=C1O[H])C1=C([H])C([H])=C([H])C(=C1[H])C([H])([H])OC1=C([H])C2=C(C([H])=C1[H])C(=O)N(C2([H])[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N1C([H])=C(C2=C1C(F)=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C3O[C@]([H])(C(=O)N([H])C3=C([H])C([H])=C2[H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N(C(=O)C1=C([H])C(C2=C([H])C([H])=C3N([H])C(=C([H])C3=C2[H])C(=O)OC([H])([H])C([H])([H])[H])=C(C([H])=N1)C([H])([H])[H])C([H])([H])C1=C([H])C([H])=NC([H])=C1[H]
[H]N(C1=C([H])C([H])=NN1C1=C([H])C([H])=C([H])C([H])=C1[H])S(=O)(=O)C1=C([H])C([H])=C(N=[N+]=[N-])C([H])=C1[H]
[H]OC(=O)C1=C([H])C([H])=C(C([H])=C1[H])N1C([H])([H])C([H])([H])C([H])(C([H])([H])N2C([H])([H])C([H])([H])C([H])(OC3=C([H])C(Cl)=C(Cl)C([H])=C3[H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]N(C(=S)N([H])C1=C([H])C(F)=C(OC2=C([H])C([H])=NC3=C2SC(=C3[H])C2=C([H])OC([H])=C2[H])C([H])=C1[H])C(=O)C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N([H])C1=C(Br)C(=NC2=C(C([H])=NN12)C1=C([H])N(N=C1[H])C([H])([H])[H])C([H])([H])[C@@]1([H])C([H])([H])N([H])C([H])([H])C1([H])[H]
[H]OC1=C([H])C([H])=C2N([H])C3=C(C([H])=C([H])[N+](=C3C([H])([H])[H])C([H])([H])[H])C2=C1[H]
[H]N1N=C(C2=NC3=C(N2[H])C([H])=C([H])C([H])=C3C([H])([H])OC([H])([H])[H])C2=C([H])C(=C([H])N=C12)C1=C([H])C([H])=NC([H])=C1[H]
[H]C1=C([H])C([H])=C([H])C(=N1)C([H])([H])C([H])([H])N1C([H])([H])C2=C(C3=C([H])C([H])=C([H])C([H])=C3N2C([H])([H])C([H])([H])C([H])([H])C(=O)C2=C([H])C([H])=C(F)C([H])=C2[H])C([H])([H])C1([H])[H]
[H]OC1=C([H])C([H])=C(C([H])=C1N([H])S(=O)(=O)C([H])([H])[H])[C@@]([H])(O[H])C([H])([H])N([H])C1([H])C([H])([H])C([H])([H])N(C2=C([H])C([H])=C(\C([H])=C3/SC(=O)N([H])C3=O)C([H])=C2[H])C([H])([H])C1([H])[H]
[H]C([H])([H])N1C2=C(N=C1C1([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])N(C(=O)N(C2=O)C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[H]
COC1=CC(=CC=C1)C1=NNC(NC(=O)CCCCN2CCCCC2)=C1
CC(C)N1CCC(CC1)OC1=C(Br)C=C2N3[C@@H](C)CNC(=O)C3=CC2=C1
[H]OC1=C(Br)C([H])=C(\C([H])=C(/[H])C(=O)C2=C([H])C([H])=C(OC([H])([H])C([H])=C(C([H])([H])[H])C([H])([H])[H])C([H])=C2[H])C(OC([H])([H])[H])=C1[H]
OC[C@@H](NC(=O)c1cc(c[nH]1)-c1nc(Nc2ccccc2)ncc1C1CC1)c1ccccc1
[H]N([H])C(=O)[C@]1(C([H])([H])C2([H])N(C([H])(C3=C([H])C([H])=C([H])C([H])=C3Cl)C3=C(Cl)C([H])=C([H])C([H])=C3[H])[C@]([H])(C([H])([H])C2([H])[H])C1([H])[H])[C@]1([H])N([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]OC(=O)[C@]([H])(OC([H])([H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C2N(C([H])=C([H])C2=C1[H])C([H])([H])C1=C(OC(=N1)C1=C([H])C([H])=C([H])C(Cl)=C1[H])C([H])([H])[H]
[H]N1C([H])=C(C2=C([H])C(C#N)=C([H])C([H])=C12)C([H])([H])C([H])([H])[C@@]1([H])N(C([H])([H])C2=C([H])C(=C([H])C(=C2[H])C(F)(F)F)C(F)(F)F)C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(C(=O)N([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC(=NC(=N1)N1C([H])([H])C([H])([H])OC([H])([H])[C@@]1([H])C([H])([H])[H])N1C([H])([H])C([H])([H])OC([H])([H])[C@@]1([H])C([H])([H])[H])C1=C([H])N=C(C([H])=C1[H])N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N1N=C(C2=NC([H])=C([H])S2)\C(=C(/[H])C2=C([H])N(C3=C2C([H])=C(Cl)C([H])=C3[H])C([H])([H])[H])C1=O
[H]N(C(=O)C1=C([H])C2=C([H])C([H])=C(OC([H])([H])[H])C(OC([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])=C2N([H])C1=O)C([H])([H])C([H])([H])F
[H]N=C(N([H])C1=C([H])C([H])=C(N([H])C(=N[H])C([H])([H])[H])C([H])=C1[H])C([H])([H])[H]
[H]C([H])(C(=O)N1[C@]([H])(C(=O)N2C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])[C@]2([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@]12[H])C([H])([H])C([H])([H])[C@]([H])(C1([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C(F)(F)F
COC1=CC2=C(CN(C[C@]3(NC(=O)NC3=O)C#CC3=CSC(=C3)C3(C)NC(=O)NC3=O)C2=O)C=C1
[H]OC(=O)[C@@]1([H])N([H])C2=C(C([H])=C(C([H])=C2[H])C(=O)OC2=C([H])C3=C([H])C([H])=C([H])C([H])=C3C([H])=C2[H])[C@@]2([H])C([H])=C([H])C([H])([H])[C@@]12[H]
[H]N1N=C([H])C([H])=C1C([H])([H])N1C([H])([H])C([H])([H])C([H])(OC2=C3C([H])=C([H])N(C3=NC([H])=N2)C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N(C(=O)C1=C([H])N=C([H])N(C1=O)C([H])([H])C1=C([H])C([H])=C(F)C(F)=C1[H])C([H])([H])C#CC1=C([H])C2=NC(N([H])[C@@]3([H])C([H])([H])C([H])([H])[C@]([H])(N(C([H])([H])[H])C([H])([H])[H])C([H])([H])C3([H])[H])=C([H])N=C2C([H])=C1[H]
[H]N(C(=O)C([H])([H])C(=O)OC([H])([H])C([H])([H])[H])C1=C([H])C(Cl)=C(OC2=C([H])C3=C(N([H])C([H])=C3C([H])(C([H])([H])[H])C([H])([H])[H])C([H])=C2[H])C(=C1[H])C([H])([H])[H]
[H]N1C(=C([H])C([H])=C1C([H])([H])N1C([H])([H])C([H])([H])N(C2=C(OC([H])([H])[H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H])C1=C(F)C([H])=C([H])C([H])=C1F
[H]OC1=C2O[C@@]3([H])C(=O)\C(=C(/[H])C4=C5C([H])=C([H])C([H])=C([H])C5=C([H])C5=C([H])C([H])=C([H])C([H])=C45)C([H])([H])[C@@]4(O[H])[C@]5([H])N(C([H])([H])C6([H])C([H])([H])C6([H])[H])C([H])([H])C([H])([H])[C@]34C2=C(C([H])=C1[H])C5([H])[H]
[H]N(C(=O)C(OC1=C([H])C([H])=C(C([H])=N1)C(F)(F)F)(C([H])([H])[H])C([H])([H])[H])[C@@]([H])(C([H])([H])[H])[C@]([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]N(C(=O)C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C(F)C([H])=C1[H])C([H])([H])C1=C2N=C([H])C(=C([H])C2=C([H])C([H])=C1[H])C([H])([H])N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H]
[H]OC(=O)[C@]1([H])N([H])C(=O)[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])[H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])SSC1([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])[H])[C@]([H])(O[H])C([H])([H])[H]
[H]OC(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@]12C([H])([H])C([H])([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[C@@]1([H])C1=C([H])C([H])([H])[C@]3([H])[C@@]4(C([H])([H])[H])C([H])([H])C([H])([H])[C@]([H])(O[H])C(C([H])([H])[H])(C([H])([H])[H])[C@]4([H])C([H])([H])C([H])([H])[C@@]3(C([H])([H])[H])[C@]1(C([H])([H])[H])C([H])([H])C2([H])[H]
[H]N1C(=O)N(C2=C(N(C(=N2)N2N=C(C([H])=C2C([H])([H])[H])C([H])([H])[H])C([H])([H])C2=C([H])C([H])=C(F)C([H])=C2[H])C1=O)C([H])([H])[H]
[H]N(C1=NC(=C([H])C([H])=C1[H])C([H])([H])[H])S(=O)(=O)C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N([H])C1=C(Cl)C([H])=C(C(=O)N([H])C2([H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C2([H])[H])C(OC([H])([H])[H])=C1[H]
[H]N1C([H])=C(C2=C1C([H])=C(Br)C([H])=C2[H])C1=C(C(=O)N([H])C1=O)C1=C([H])N(C2=C1C([H])=C([H])C([H])=C2[H])C([H])([H])[H]
[H]N(C(=O)N1C([H])([H])C([H])([H])N(C(=O)C2([H])C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])C([H])([H])C([H])([H])C1([H])[H])C1=NOC(=C1[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]OC(=O)C1=C([H])C([H])=C([H])C(=C1[H])N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@]([H])(C([H])([H])N([H])C(=O)C2=C(N=C(S2)C2=C([H])C([H])=C(Cl)C([H])=C2[H])C([H])([H])[H])C1([H])[H]
[H]ON([H])C(=O)C1(C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])S(=O)(=O)C1=C([H])C([H])=C(OC2=C([H])C([H])=C(OC(F)(F)F)C([H])=C2[H])C([H])=C1[H]
[H]N(C(=O)C(C1=C([H])C([H])=C(N([H])S(=O)(=O)C([H])([H])[H])C(F)=C1[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]C([H])([H])[N+]1=C(C(C(=O)OC([H])([H])C([H])([H])[H])=C(C(C(=O)SC([H])([H])C([H])([H])[H])=C1C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]C1=NC2=C([H])C([H])=C(C([H])=C2C([H])=C1C([H])([H])C([H])([H])[H])C(=O)[C@]1([H])C([H])([H])C([H])([H])[C@]([H])(OC([H])([H])[H])C([H])([H])C1([H])[H]
[H]N(N([H])C1=C2C([H])=C([H])C([H])=C([H])C2=NC2=C1C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=O)C1=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C(OC([H])([H])[H])=C1[H]
[H]N([H])C(=O)C1=C([H])C([H])=C(C([H])=C1[H])C1=C2C([H])=C([H])C([H])=C([H])C2=C(N=N1)N([H])C1=C([H])C(Cl)=C(Cl)C([H])=C1[H]
[H]C1=C(Cl)C([H])=C(C(C#N)=C1[H])C([H])([H])N(C([H])([H])[H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H]
NCCSC(C1=CC=CC=C1)(C1=CC=CC=C1)C1=CC=C2CCCCC2=C1
[H]OC1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])N([H])C1=NC(=NC(=N1)N(C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C(Cl)C([H])=C1[H])N1C([H])([H])C([H])([H])N(C([H])([H])C(=O)C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]OC(=O)[C@@]1([H])OC2=C(OC1([H])[H])C([H])=C(SC1=C([H])C([H])=C(\C([H])=C(/[H])C(=O)N3C([H])([H])C([H])([H])N(C(=O)C([H])([H])[H])C([H])([H])C3([H])[H])C([H])=C1Cl)C([H])=C2[H]
[H]N([H])C1=C2C([H])=C([H])C(=C([H])C2=NC([H])=N1)C([H])([H])N1C(=O)C([H])([H])N(C([H])([H])C1([H])[H])S(=O)(=O)C1=C([H])C2=C(S1)C([H])=C(Cl)C([H])=C2[H]
[H]OC(=O)C1=NN([H])C2=C1C([H])([H])[C@@]([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C2([H])[H]
[H]N(C(=O)C1=C([H])N(C2=C(OC([H])([H])[H])C([H])=C([H])C(OC([H])([H])[H])=C2C1=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])[C@]12C([H])([H])[C@@]3([H])C([H])([H])[C@]([H])(C([H])([H])[C@]([H])(C3([H])[H])C1([H])[H])C2([H])[H]
[H]OC1=C(F)C(=C(F)C([H])=C1[H])C1=C([H])C(=C2N=C(N=NC2=C1[H])N([H])C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])[H]
[H]N(C(=O)[C@@]1([H])C([H])([H])N(C(=O)C([H])([H])C([H])([H])C2([H])C([H])([H])C([H])([H])N([H])C([H])([H])C2([H])[H])C([H])([H])C([H])([H])C1([H])[H])[C@]([H])(C1=C([H])N=C([H])C([H])=C1[H])C([H])([H])C(=O)OC([H])([H])C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(N([H])C(=O)C([H])([H])SC1=NN=C(N1N([H])C(=O)C1=C([H])C([H])=C(Cl)C([H])=C1[H])C([H])([H])C1=C([H])SC(=N1)N([H])C(=O)C([H])([H])[H])C(=O)C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C1=C([H])C([H])=C2C(=O)C(=C(N3C([H])([H])C4=C([H])C([H])=C([H])C([H])=C4C([H])([H])C3([H])[H])C([H])([H])[H])C(=O)C2=C1[H]
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[H]OC(=O)[C@]([H])(N([H])C(=O)[C@@]1([H])N(C(=O)[C@@]([H])(N([H])C([H])([H])[C@@]([H])(N([H])[H])C([H])([H])S[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2C1([H])[H])C([H])([H])C([H])([H])S(=O)(=O)N([H])[H]
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[H]N1C([H])=NC(=C1C([H])([H])[H])C1([H])C([H])([H])C([H])([H])N(C2=NC([H])=NC([H])=C2C2=C([H])C([H])=C(Cl)C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N=C(N([H])[H])[C@]1([H])N([H])C([H])([H])C([H])=C1[H]
[H]C1=C([H])C(OC([H])([H])[H])=C2C(=C1[H])[C@]([H])(OC([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])(C([H])([H])C1([H])[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C([H])([H])C2([H])[H]
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[H]N(C(=O)C([H])([H])C1=NC2=C(N1[H])C(=C([H])C([H])=C2[H])C(F)(F)F)[C@@]1([H])C([H])([H])C([H])([H])[C@@]([H])(N(C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])[C@@]1([H])C([H])([H])S(=O)(=O)C1=C([H])C([H])=C(Br)C([H])=C1[H]
[H]N(C(=O)C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)OC([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])[H])C([H])([H])C1=C([H])N=C([H])C([H])=C1[H]
[H]N1N=NC(=N1)C1=C([H])C([H])=C([H])C([H])=C1C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1C(=O)N(N=C1C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C#N
[H]N1C2=C(C(C(=O)OC([H])(C([H])([H])[H])C([H])([H])[H])=C1C([H])([H])[H])C1=C(O[C@]3([H])N(C1([H])[H])C([H])([H])C([H])([H])C1=C([H])C(OC([H])([H])[H])=C([H])C([H])=C31)C([H])=C2[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C2=C(O[C@@]3(C2([H])[H])C([H])([H])[N@]2C([H])([H])C([H])([H])[C@]3([H])C([H])([H])C2([H])[H])N=C1[H]
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[H]N=C(N([H])[H])C1=C([H])C([H])=C(N([H])C(=O)N([H])C([H])([H])C(=O)N([H])C([H])([H])C2=C([H])C([H])=C([H])C(Br)=C2[H])C([H])=C1[H]
[H]OC1=C([H])C(=C([H])C([H])=C1[H])[C@]1(C(=O)OC([H])([H])C([H])([H])[H])C([H])([H])N(C([H])([H])C([H])=C([H])[H])C([H])([H])C([H])([H])C1([H])[H]
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[H]N(C1=NC(=C([H])C2=C1C(=O)N([H])C([H])=C2[H])C1=C([H])N=C([H])N=C1[H])C1=C([H])C([H])=C(C(=C1[H])C([H])([H])[H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])C1([H])C([H])([H])C1([H])[H]
[H]N(C(=O)C(\[H])=C(/[H])C1=C(OC([H])([H])[H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])C1=C([H])C(=C([H])C([H])=N1)C1=C(N=C(SC([H])([H])[H])N1C([H])([H])C([H])([H])[H])C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]C1=NC(=C([H])C([H])=C1OC([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])[C@]([H])(C([H])=O)C([H])([H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H]
[H]C1=C(C2=NC(=NN2C([H])([H])[H])N(C([H])([H])C([H])([H])C([H])([H])[H])C([H])(C2([H])C([H])([H])C2([H])[H])C2([H])C([H])([H])C2([H])[H])C(Cl)=C([H])C(Cl)=C1F
[H]N1C([H])=NC(=C1[H])C([H])([H])C([H])([H])C([H])([H])OC([H])([H])C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]O[C@@]1([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])N(C(=O)N([H])C2=C([H])C([H])=C(F)C(Cl)=C2[H])[C@]2([H])C([H])([H])C([H])([H])[C@]3(C4=C([H])C([H])=C([H])C(C#N)=C4[H])C([H])([H])[C@]23[H])C([H])([H])C1([H])[H]
[H]C([H])=C([H])C([H])([H])N1C([H])=NC2=C1C(=O)N(C(=O)N2C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[H]
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[H]N([H])C1=C2N=C([H])C([H])=C([H])C2=C(C(=C1[H])S(=O)(=O)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H])[N+]([O-])=O
[H]N(OC([H])([H])[H])C(=O)C1=C([H])C([H])=C(C(N([H])C2=NC(=NC(=N2)N(C([H])([H])[H])C([H])([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])N2C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C([H])([H])C2([H])[H])=C1[H])C([H])([H])[H]
[H]C1=C([H])N=C(O1)C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])[C@]([H])(C2=NC3=C([H])C([H])=C([H])C([H])=C3N2C([H])([H])C([H])([H])OC2=C([H])C([H])=C([H])C([H])=C2[H])C1([H])[H]
CCCCN(C(=O)C1=CC=CC=C1F)C1=NN=C(S1)C1=CC=CN=C1
[H]ON([H])C(=O)[C@]1([H])N(C([H])([H])[C@@]([H])(N2C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])C1([H])[H])S(=O)(=O)C1=C([H])C([H])=C(OC2=C([H])C([H])=C([H])C([H])=C2[H])C([H])=C1[H]
[H]N(C1=NOC2=C([H])C(=C([H])C([H])=C12)C(F)(F)F)C1=C([H])C([H])=C(C([H])=C1[H])C(F)(F)F
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[H]OC(=O)C1=C([H])C2=C(OC([H])([H])C3=C([H])C([H])=C([H])C([H])=C3[C@@]2([H])SC([H])([H])C([H])([H])N2C([H])([H])C([H])([H])C([H])(C3=C([H])C([H])=C([H])C([H])=C3[H])C([H])([H])C2([H])[H])C([H])=C1[H]
[H]N1C2=C([H])C(=C(C([H])=C2N=C(C2=C([H])C([H])=C([H])C(=C2[H])N2C([H])=NC([H])=C2[H])C([H])([H])C1=O)C([H])([H])C([H])([H])[H])C(F)(F)F
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[H]N(C(=O)OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C(F)(F)C(=O)[C@@]([H])(N([H])C(=O)[C@@]1([H])N(C(=O)[C@@]([H])(N([H])C(=O)OC([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C1([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N([H])C(=O)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])[C@]([H])(N([H])C([H])([H])C(=O)C1=C([H])C([H])=C(Cl)C([H])=C1[H])C([H])([H])[H]
[H]N=C(N([H])[H])N([H])C([H])([H])C([H])([H])C([H])([H])[C@]([H])(N([H])C(=O)[C@@]1([H])N2N(C([H])([H])C1([H])[H])C([H])([H])C([H])([H])[C@](N([H])[H])(C2=O)C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C(=O)C1=NC([H])=C([H])S1
[H]N(C(=O)C1=C([H])C([H])=C([H])C2=C([H])C(OC3=C4C([H])=C(OC([H])([H])[H])C(OC([H])([H])[H])=C([H])C4=NC([H])=C3[H])=C([H])C([H])=C12)C1=C([H])C([H])=NC([H])=C1[H]
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[H]N(C(=O)C([H])([H])[H])C1(C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])N(C([H])([H])[C@]2([H])C([H])([H])[C@@]2(C(=O)N(C([H])([H])[H])C([H])([H])C2=C([H])C([H])=C(F)C([H])=C2[H])C2=C([H])C([H])=C(Cl)C([H])=C2[H])C([H])([H])C1([H])[H]
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[H]N([H])[C@@]([H])(C([H])([H])[H])C1(C2=C([H])C([H])=C([H])C3=C([H])C([H])=C([H])C([H])=C23)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N1C(=O)N(C2=NN(C([H])=C2[H])C2=C3C(=NC(=C2[H])C([H])([H])[H])N(C2=C([H])C([H])=C(C#N)C([H])=C2C([H])([H])C([H])([H])[H])C([H])([H])C3([H])[H])C([H])([H])C1([H])[H]
[H]OC(=O)C1=C([H])C([H])=C([H])C([H])=C1C1=C([H])C([H])=C([H])C([H])=C1C(=O)N([H])C1=C([H])C([H])=C(\C([H])=C(/[H])C(=O)C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])=C1[H]
[H]OC(=O)C([H])([H])C([H])([H])C1=C([H])C([H])=C2N([H])C(=C(C2=C1[H])C([H])([H])C1=C([H])C([H])=NC([H])=C1[H])C([H])([H])[H]
[H]N(C(=O)N([H])C1=C([H])C(N([H])C(=O)C2=C([H])C3=C(N2[H])C([H])=C([H])C([H])=C3[H])=C([H])C([H])=C1[H])C(=O)C1=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C(OC([H])([H])[H])=C1[H]
[H]N([H])C(=O)C1=C([H])N=C(N=C1N([H])C1=C([H])C(=C([H])C([H])=C1[H])C([H])([H])[H])N([H])[C@@]1([H])C([H])([H])N([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N1N(C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])[C@]([H])(C1=O)C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H]
[H]OC(=O)[C@]([H])(N([H])S(=O)(=O)C1=C([H])C([H])=C(OC([H])([H])C#CC([H])([H])[H])C([H])=C1[H])C([H])([H])C1=C([H])N([H])C2=C1C([H])=C([H])C(F)=C2[H]
[H]OC(=O)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])N1C(=O)C([H])([H])C([H])([H])[C@]1([H])C(\[H])=C(/[H])[C@@]([H])(O[H])C([H])([H])C1=C([H])C([H])=C([H])C(=C1[H])C([H])([H])OC([H])([H])[H]
[H]N(C(=O)C1=NC(=C([H])C([H])=C1N([H])C1=C([H])N=C([H])N=C1[H])C1([H])C([H])([H])C1([H])[H])C1=NN(C(=C1[H])C1=C([H])C([H])=C([H])C([H])=N1)C([H])([H])[H]
[H]OC(=O)C1=C([H])C(=C([H])C([H])=C1OC1=NC(OC2=C([H])C(=C([H])C([H])=C2[H])C(=N[H])N([H])[H])=C(F)C(N(C([H])(C([H])([H])[H])C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])=C1F)C(=O)N([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1Cl
[H]N([H])C1=NC([H])([H])C([H])([H])[C@]([H])(C1([H])[H])C(F)(F)F
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[H]N1C(=O)S[C@@]([H])(C1=O)C([H])([H])C1=C([H])C([H])=C(OC([H])([H])C([H])([H])C2=C([H])C([H])=C(C([H])=C2[H])C([H])([H])C([H])([H])[H])C([H])=C1[H]
[H]N(C([H])([H])[H])C([H])([H])C1=C([H])C(=C([H])C([H])=C1OC1=C([H])C([H])=C(C#N)C([H])=C1[H])C(=O)N1C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C1([H])[H])C1([H])C([H])([H])C1([H])[H]
[H]N([H])[C@]([H])(C1=C(C([H])=C([H])C(=C1[H])C(F)(F)F)N1C([H])([H])C([H])([H])N(C(=O)[C@]2([H])C([H])([H])N(C3=C([H])C([H])=C([H])C([H])=C3[H])C([H])([H])[C@@]2([H])C2=C([H])C([H])=C(Cl)C([H])=C2[H])C([H])([H])C1([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]OC1=C([H])C([H])=C([H])C([H])=C1C1=NC2=C([H])C([H])=C([H])C([H])=C2C(=C1[H])C(=O)N([H])[C@@]([H])(C(=O)OC([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C1=C([H])C([H])=C([H])C([H])=C1C([H])([H])[H])C1=C(C([H])=NC2=C(OC3=C([H])C([H])=NC(Cl)=C3[H])C([H])=C([H])C([H])=C12)C(=O)C([H])([H])C([H])([H])C([H])([H])[H]
[H]N(C(=O)C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])S(=O)(=O)C1=C([H])C([H])=C([H])C([H])=C1C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1C(=O)N(N=C1C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1C(F)(F)F
[H]N(C(=O)C([H])([H])N1C([H])([H])C(=O)N(C([H])([H])C([H])([H])[H])C([H])([H])C1([H])[H])[C@]1(C(=O)N([H])C2=C([H])C(Cl)=C([H])C(Cl)=C12)C1=C([H])C(Cl)=C(Cl)C([H])=C1[H]
[H]C1=C([H])C(Cl)=C(N2C(=O)C([H])=C([H])C3=C2C([H])=C(C([H])=C3C2=C([H])C([H])=C(F)C([H])=C2Cl)C2=C([H])C([H])([H])N(C([H])([H])C2([H])[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C(Cl)=C1[H]
[H]N(C([H])([H])C([H])([H])N1C2=C(OC([H])([H])C1([H])[H])C([H])=C(F)C(F)=C2[H])[C@@]1([H])C([H])([H])C([H])([H])[C@]([H])(C([H])([H])N([H])S(=O)(=O)C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]C1=C2N=C(SC2=C([H])C(=N1)C1=C([H])N=C(F)C([H])=C1[H])N1C([H])([H])C([H])([H])C([H])(N2C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]\C(=C(\[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C(=O)O[C@@]1([H])C([H])([H])[C@]2([H])C([H])([H])[C@]3(OC2(C([H])([H])[H])C([H])([H])[H])[C@]([H])(C([H])([H])[H])[C@@]([H])(OC(=O)C([H])([H])[H])[C@@]([H])(OC(=O)C([H])([H])[H])[C@]([H])(OC(=O)C2=C([H])C([H])=C([H])C([H])=C2[H])[C@@]13C([H])([H])[H]
[H]OC1=C([H])C(O[H])=C(C([H])=C1C(=O)C(\[H])=C(/[H])C1=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C([H])=C1[H])C(=O)C(\[H])=C(/[H])C1=C([H])C([H])=C(OC([H])([H])[H])C(OC([H])([H])[H])=C1[H]
[H]N1C2=NC([H])=C([H])N=C2C(=C1C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])[H]
CC1=CC(Cl)=C(OCCOC2=CC=C(CC(CN)C3=C(C)C=C(C=C3)C3=CC(N)=NC=C3)C=C2)C(Cl)=C1
[H]N(C(=O)N([H])C1=C(OC2=C([H])C(=C(C([H])=C2[H])C([H])([H])[H])C([H])([H])[H])C([H])=C([H])C(=C1[H])C(=O)N([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C(Br)C([H])=C1[H]
[H]OC1=C([H])C([H])=C(N([H])C(=O)C2=NC([H])=NC(=C2[H])N(C([H])([H])[H])C2([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])=C1[H]
[H]S\C(=N\C([H])([H])C1=C([H])C([H])=C([H])N=C1[H])N1C([H])([H])C([H])([H])N(C2=NC([H])=NC3=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C([H])=C23)C([H])([H])C1([H])[H]
[H]N1C(=O)C([H])=C([H])C2=C(C(=C([H])C([H])=C12)C([H])([H])[H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C([H])C([H])=C([H])C3=NC(=C([H])C([H])=C23)C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N([H])C(=O)[C@@]([H])(N([H])[C@@]1([H])C([H])([H])C([H])([H])[C@@]([H])(C([H])([H])C1([H])[H])[C@@]1([H])C2=C(N([H])C1([H])[H])C([H])=C([H])C([H])=C2[H])C1([H])C([H])([H])C([H])([H])N(C(=O)C(\[H])=C(/[H])C2=C([H])C(F)=C(F)C(F)=C2[H])C([H])([H])C1([H])[H]
[H]N1C([H])=C(C2=C([H])C(C#N)=C([H])C([H])=C12)[C@@]1([H])C([H])([H])C([H])([H])[C@]([H])(N2C([H])([H])C3=C(C([H])=C(OC([H])([H])C([H])([H])C([H])([H])F)C([H])=C3[H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]ON([H])C(=O)[C@@](C([H])([H])[H])(C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])S(=O)(=O)C1=C([H])C([H])=C([H])S1
[H]N([H])S(=O)(=O)C1=C(C([H])=C([H])C([H])=C1[H])C1=C([H])N=C(N=C1[H])N([H])C(=O)C1=C([H])C(=NN1C1=C(C([H])=C2C([H])=C([H])C([H])=C([H])C2=C1[H])S(=O)(=O)C([H])([H])[H])C([H])([H])[H]
[H]ON(C(=O)C([H])([H])[H])[C@]([H])(C1=C([H])C2=C(OC(=C2[H])C2=C([H])C3=C([H])C([H])=C(OC([H])([H])[H])C([H])=C3C([H])=C2[H])C([H])=C1[H])C([H])([H])[H]
[H]O[C@@]1([H])C(=O)O[C@@]([H])(C([H])([H])N2C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])C([H])([H])C([H])([H])C([H])([H])C(=O)OC([H])([H])[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])[C@@]2([H])C([H])([H])[N@]3C([H])([H])C([H])([H])[C@]2([H])C([H])([H])C3([H])[H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C(=O)N([H])[C@@]1([H])C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]O[C@]([H])(C([H])([H])N1C([H])([H])C([H])([H])N(C2=C(Cl)C(Cl)=C([H])C([H])=C2[H])C([H])([H])C1([H])[H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C2C3=C(C([H])=C([H])C([H])=C3[H])C([H])([H])C2=C1[H]
[H]C([H])=C([H])C([H])([H])[C@]1([H])OC2=C([H])C([H])=C([H])C(Cl)=C2C2=C1C1=C(N([H])C(C([H])=C1C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])=C2[H]
CC(C)OC(=O)N1C2CC3CC1CC(C2)N3C1=NC=NC(OC2=CC=C(C=C2F)C(=O)N(C)C)=C1C
[H]N(C(=O)N1C([H])([H])[C@@]2([H])C([H])([H])[C@@]([H])(N([H])C([H])([H])C(=O)N3C([H])([H])C([H])([H])C([H])([H])[C@@]3([H])C#N)C([H])([H])[C@@]2([H])C1([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]OC([H])([H])[C@@]1([H])N(C([H])([H])C([H])([H])C([H])([H])OC2=C(OC([H])([H])[H])C([H])=C3C(=NC([H])=NC3=C2[H])N([H])C2=NC([H])=C(S2)C([H])([H])C(=O)N([H])C2=C([H])C(OC([H])([H])[H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N(C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])S(=O)(=O)C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C1=C([H])N(C([H])=N1)C([H])([H])C1=C([H])C([H])=C(C#N)C(OC2=C([H])C(Br)=C([H])C([H])=C2[H])=C1[H]
[H]O[C@@]([H])(C([H])([H])N(C1=C([H])C(OC2=C([H])C([H])=C(C([H])=C2[H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C(OC(F)(F)C([H])(F)F)=C1[H])C(F)(F)F
[H]N(N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H])C(=O)N1C(=O)N(C2=C([H])C([H])=C([H])C([H])=C12)C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N1C(=NC([H])([H])C([H])([H])C1([H])[H])C([H])([H])C1=C(C([H])=C(C([H])=C1C([H])([H])[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H]
[H]O[C@](C1=C([H])C2=C([H])C(Cl)=C(C([H])=C2N1[H])C(F)(F)F)(C([H])([H])[H])C([H])([H])OC(=O)C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[C@]([H])(N([H])[H])C(=O)N([H])C([H])([H])C(=O)N([H])C([H])([H])C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]1([H])C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@@]([H])(C(=O)N([H])[C@]([H])(C(=O)N2C([H])([H])C([H])([H])C([H])([H])[C@@]2([H])C(=O)N([H])[C@]([H])(C(=O)N([H])[H])C([H])([H])SSC1([H])[H])C([H])([H])C([H])([H])C([H])([H])N=C(N([H])[H])N([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])N=C(N([H])[H])N([H])[H])C([H])([H])C([H])([H])C([H])([H])N=C(N([H])[H])N([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C1=C(C(=O)N(C(=O)N1C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C([H])C([H])=C([H])C([H])=C2OC([H])([H])[H])C([H])([H])C1([H])[H]
[H]C1=C([H])C(OC2=C([H])C([H])=C(C([H])=C2[H])S(=O)(=O)C([H])([H])[C@@]2([H])SC2([H])[H])=C([H])C([H])=C1F
[H]N(C(=O)N1C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C(OC2=C([H])C([H])=C([H])C([H])=C2[H])C([H])=C1[H]
[H]O[C@@]1(C(=O)C(=O)N2[C@@]3([H])C(=O)OC([H])([H])C([H])([H])C([H])([H])OC(=O)[C@]2([H])C([H])([H])C([H])([H])C3([H])[H])C([H])([H])[C@@]([H])(C([H])([H])C([H])([H])[C@@]1([H])C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N([H])C1=C2C(=NC([H])=N1)N(N=C2C1=C([H])C(=C([H])C([H])=C1[H])C(=O)N([H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])(C([H])([H])[H])C([H])([H])[H])[C@@]1([H])C([H])([H])N(C(=O)C([H])=C([H])[H])C([H])([H])C([H])([H])C1([H])[H]
[H]OC(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])S(=O)(=O)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C(=O)N([H])[C@@]([H])(C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])[C@@]([H])(O[H])[C@]([H])(O[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C1=C([H])C([H])=C([H])C(=C1[H])[N+]([O-])=O)C1=C(C#N)C([H])=NC2=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C([H])=C12
[H]OC(=O)C1=C(OC([H])([H])[H])C(=C([H])C([H])=C1N([H])S(=O)(=O)C1=C([H])C([H])=C(F)C([H])=C1[H])C([H])([H])C([H])([H])[H]
[H]C1=C([H])C(=C([H])C(=C1[H])C(F)(F)F)N1C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])C([H])([H])N2C(=O)C([H])([H])SC2([H])[H])C([H])([H])C1([H])[H]
[H]OC1=C([H])C(=C(C(=C1[H])C([H])([H])[H])C([H])([H])[C@]([H])(N([H])[H])C(=O)N1C([H])([H])C2=C(C([H])=C([H])C([H])=C2[H])C([H])([H])[C@@]1([H])C(=O)N([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@]([H])(N([H])C(=O)OC([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C(=O)N([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H]
[H]OC([H])([H])C(N1C([H])([H])C([H])([H])N(C(=O)OC2(C([H])([H])C2([H])[H])[C@]2([H])N([C@]([H])(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C2([H])[H])S(=O)(=O)C2=C([H])C([H])=C(Cl)C([H])=C2[H])C([H])([H])C1([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])[C@@]([H])(OC([H])([H])C([H])([H])[H])C([H])([H])N1N=C(N(C1=O)C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1C1=NN(N=N1)C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]N(C1=NC([H])=C(Cl)C(=N1)N([H])C1=C(F)C([H])=C([H])C([H])=C1C(=O)N([H])C([H])([H])[H])C1=C([H])C([H])=C2N(C(=O)OC([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])OC2=C1[H]
[H]N([H])C([H])([H])C([H])([H])N([H])C(=O)C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])N=C2C([H])=C([H])C(=NN12)N([H])C([H])([H])C1=C([H])C(Cl)=C(Cl)C([H])=C1[H]
[H]OC1=C([H])C(=C(C(=C1[H])C([H])([H])[H])C([H])([H])[C@]([H])(N([H])C([H])=O)C(=O)N([H])[C@@]1([H])C(=O)N([H])[C@]([H])(C(=O)N2C([H])([H])C([H])([H])C([H])([H])[C@]2([H])C(=O)N([H])C([H])([H])C(=O)N([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C1=C([H])C2=C([H])C([H])=C([H])C([H])=C2C([H])=C1[H])C([H])([H])[H]
[H]N(N1C(SC([H])([H])C#N)=NN=C1C([H])([H])C1=C([H])SC(=N1)N([H])C(=O)C([H])([H])Cl)C(=O)C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C1=NC2=C([H])C([H])=C([H])C([H])=C2C2=C1C([H])=C([H])N=C2[H])C1=C([H])C([H])=C([H])C(Cl)=C1[H]
[H]OC([H])([H])C([H])([H])C([H])([H])S(=O)(=O)C1=C([H])C(OC2=C([H])C([H])=C([H])C(=C2[H])C2=C3C([H])=C([H])C([H])=C(C3=NC([H])=C2C([H])([H])[H])C(F)(F)F)=C([H])C([H])=C1[H]
[H]N(C(=O)N([H])C1([H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC(N2C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])=C2C([H])=NN(C2=N1)C1([H])C([H])([H])C([H])([H])N(C(=O)OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N1N=NC(=N1)C1=C(C(Cl)=C([H])C([H])=C1[H])C([H])([H])N1C([H])=C([H])C2=C([H])C(=C([H])C([H])=C12)C([H])([H])N1C2=C(N=C1C([H])([H])C([H])([H])[H])C(=C([H])C(=N2)C([H])([H])[H])C([H])([H])[H]
[H]OC1=C([H])C(\C([H])=C2/OC3=C(C([H])=C([H])C(OC([H])([H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C4=C([H])C([H])=C([H])C(OC(=O)N([H])C([H])([H])[H])=C4[H])=C3[H])C2=O)=C([H])C(O[H])=C1O[H]
[H]C1=C(N=NN1C([H])([H])C([H])([H])F)C([H])([H])N1C(=O)C(=O)C2=C1C([H])=C([H])C(=C2[H])S(=O)(=O)N1C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C([H])([H])OC1=C([H])C([H])=C([H])N=C1[H]
[H]N(C(=O)[C@@]([H])(N([H])[C@@]([H])(C1=C([H])C([H])=C(C([H])=C1[H])C1=NC(=NO1)C([H])([H])[H])C(F)(F)F)C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C#N
[H]N(C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C(=O)N1C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])[C@]([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]O[C@]([H])(C(=O)N([H])C1=C([H])C([H])=C(N([H])C(=O)C2=C([H])C([H])=C(OC([H])([H])[H])C([H])=C2[H])C([H])=C1[H])[C@]([H])(N([H])[H])C([H])([H])C([H])([H])SC([H])([H])C([H])([H])[H]
[H]\C(=C1\S\C(=N/C2=C([H])C([H])=C(C([H])=C2[H])C(=O)OC([H])([H])C([H])([H])[H])N(C1=O)C1=C([H])C([H])=C(C([H])=C1[H])C(=O)OC([H])([H])C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]ON([H])C(=O)[C@]([H])(N([H])S(=O)(=O)C1=C([H])C([H])=C(F)C(=C1[H])C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]O[C@@]([H])(C([H])([H])OC1=C([H])C([H])=C(N([H])C2=NC([H])=C([H])C(=N2)N([H])C2=C([H])C([H])=C([H])C([H])=C2Br)C([H])=C1[H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H]
[H]OC1=C([H])C([H])=C([H])C(=C1[H])C([H])([H])N(C(=O)C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C([H])C(=C1[H])C([H])([H])[H])C([H])([H])[H]
[H]N([H])S(=O)(=O)C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C(F)C(F)=C1C1=C([H])C(=C(Cl)C([H])=C1[H])C([H])([H])[H]
[H]N(C(=O)C([H])([H])OC1=C([H])C(=C([H])C([H])=C1[H])C([H])([H])[H])C([H])([H])C1([H])C([H])([H])N(C([H])([H])C2=C([H])N(C([H])=C2[H])C2=NC([H])=C(C([H])=C2[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C1([H])[H]
[H]OC(=O)C([H])([H])OC1=C([H])C(=C([H])C([H])=C1[H])[C@]([H])(OC(=O)[C@@]1([H])N(C([H])([H])C([H])([H])C([H])([H])C1([H])[H])S(=O)(=O)C1=C([H])C2=C(N=C([H])S2)C([H])=C1[H])C([H])([H])C([H])([H])C1=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]N(C(=O)C1([H])C([H])([H])C([H])([H])C1([H])[H])C1=NN([H])C2=C1C([H])=NC(OC1=C(F)C([H])=C(F)C([H])=C1[H])=N2
[H]OC([H])([H])[C@@]([H])(N([H])C(=O)[C@@](N([H])C(=O)O[C@]12C([H])([H])[C@@]3([H])C([H])([H])[C@]([H])(C([H])([H])[C@]([H])(C3([H])[H])[C@@]1([H])Cl)C2([H])[H])(C([H])([H])[H])C([H])([H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C1=NN=NN1C1=C([H])C([H])=C([H])C([H])=C1C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1C(=C([H])N=C1C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C(=O)OC([H])([H])[H]
[H]C([H])=C(C1=C([H])C([H])=C(C([H])=C1[H])[C@@]1([H])C([H])([H])[C@@]2([H])N([H])[C@]([H])(C([H])([H])C2([H])[H])[C@@]1([H])C(=O)C([H])([H])C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)[C@@]1([H])C([H])([H])C([H])([H])OC([H])([H])C1(C([H])([H])[H])C([H])([H])[H])C([H])([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])N(C1=NS(=O)(=O)C2=C([H])C(F)=C([H])C([H])=C12)C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N1C2=C([H])C([H])=C(C([H])=C2C(OC([H])([H])C1=O)(C1=C([H])C(Cl)=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C(Cl)=C1[H])C1=C([H])C([H])=C(C#N)N1C([H])([H])[H]
[H]N=C(N([H])[H])C1=C([H])C([H])=C2C([H])=C([H])C(=C([H])C2=C1[H])C([H])([H])N(C1([H])C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])S(=O)(=O)C1=C([H])C(Cl)=C([H])C([H])=C1[H])S(=O)(=O)C([H])([H])[H]
[H]OC([H])([H])C1=NN(C(=C1[H])C1=C([H])C2=C(OC([H])([H])C(=O)N2[H])C([H])=C1[H])C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]O[C@@]([H])(C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])[C@]([H])(O[H])[C@@]([H])(N([H])C(=O)[C@@]([H])(SC1=C([H])C([H])=C([H])S1)N([H])C(=O)[C@@]([H])(N([H])S(=O)(=O)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]OC(=O)C([H])([H])[C@]1([H])N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@]2([H])N(C1=O)C([H])([H])C([H])([H])C2([H])[H])C1=C([H])C([H])=C([H])S1)C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H]
[H]N(C(=O)C1=C([H])C([H])=C2C([H])=C([H])C([H])=C([H])C2=C1[H])C1=C([H])C([H])=C(N([H])C(=O)[C@@]([H])(N2C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C2([H])[H])C2=C([H])C([H])=C([H])C([H])=C2[H])C(=C1[H])C(=O)C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]O[C@]1(C2=C([H])C(F)=C(F)C([H])=C2[H])C([H])([H])C([H])([H])N([H])C([H])([H])[C@]1([H])C1=NOC(=C1C(=O)C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1C([H])([H])C([H])([H])N([H])C(=O)C([H])([H])[H]
[H]N1C(=NC2=C1C(=O)N(C(=O)N2[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C1=C([H])N(N=C1[H])C([H])([H])C1=C([H])C(=C([H])C([H])=C1[H])C(F)(F)F
[H]C1=C([H])C(=C(Cl)C([H])=C1N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])S(=O)(=O)N1C([H])([H])C([H])([H])N(C2=C([H])C([H])=C(F)C([H])=C2C(F)(F)F)C([H])([H])[C@@]1([H])C([H])([H])[H]
[H]OC1(C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])[C@]([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)[C@]([H])(N([H])S(=O)(=O)C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H])C1=NN=C(C2=C([H])C([H])=C(Br)C([H])=C2[H])C([H])([H])S1
[H]C#CC([H])([H])N1C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])C1(C(=O)N([H])C(=O)N([H])C1=O)C([H])([H])N([H])C(=O)C1=C([H])C([H])=C(OC([H])([H])C2=C([H])C(=NC3=C([H])C([H])=C([H])C([H])=C23)C([H])([H])[H])C([H])=C1[H]
[H]N([H])C1=C([H])C([H])=C([H])C(=C1[H])C([H])([H])N(C(=O)[C@]12C([H])([H])[C@@]3([H])C([H])([H])[C@]([H])(C([H])([H])[C@]([H])(C3([H])[H])C1([H])[H])C2([H])[H])C([H])([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C([H])C([H])=C1[H])S(=O)(=O)C1=C(C([H])=C(S1)C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1C2=NC(=C([H])C(=C2N=C1C([H])([H])C([H])([H])[H])C([H])([H])[H])C([H])([H])[H]
[H]N1C([H])([H])C([H])([H])C2=C([H])C([H])=C(F)C([H])=C2[C@]([H])(C([H])([H])[H])C1([H])[H]
[H]N([H])C(=O)C([H])([H])C([H])([H])N1C(=NC2=C([H])C(=C([H])C([H])=C12)C([H])([H])N(C([H])([H])[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])N([H])C(=O)C1=C([H])C([H])=C(C#N)C([H])=C1[H]
[H]OC(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C(\[H])=C(\[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N(C(=O)N(C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])[H]
[H]C([H])=C([H])C([H])([H])N(C(=O)C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)C([H])([H])[H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])(C2=C([H])C([H])=C([H])C([H])=C2[H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]OC1=C(OC([H])([H])[H])C([H])=C([H])C(OC([H])([H])[H])=C1C(=O)N([H])C([H])([H])[C@@]1([H])N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C1([H])[H]
[H]SC1=NN2C(S1)=NN=C2C([H])([H])[H]
[H]N1C([H])=NC(=C1[H])C([H])([H])C1=C([H])C([H])=C(Br)C([H])=C1[H]