[H]OC([H])([H])C([H])([H])N([H])S(=O)(=O)C1=C([H])C([H])=C2N=C(C3=C(C(=O)N(C3=O)C3=C(N(N=C3C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C2=C1[H])C([H])([H])[H]
[H]OC(=O)[C@]([H])(OC1=C([H])C([H])=C([H])C(=C1[H])C([H])([H])N1C2=C([H])C(OC(F)(F)F)=C([H])C([H])=C2C(C(=O)C2=C([H])C([H])=C(Cl)C([H])=C2[H])=C1C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]O[C@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])N([H])C1=NC(=C([H])C(OC2=C3N=C(N([H])[H])C(=O)N([H])C3=C([H])C([H])=C2[H])=N1)C1=C([H])C([H])=C(C([H])=C1[H])C(F)(F)F
[H]N(C(=O)C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C(\C([H])=C2\C3=NC4=C([H])C(Cl)=C([H])C([H])=C4C(=O)N3C([H])([H])C2([H])[H])C([H])=C1[H]
[H]C1=C([H])C(Cl)=C(S1)C1=NC(=NO1)C1=C([H])N=C(C([H])=C1[H])C(F)(F)F
[H]N(C(=O)C1=C([H])N(C2=C([H])C(SC3=C([H])C([H])=C([H])C([H])=C3[H])=C([H])C([H])=C2C1=O)C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H])[C@]1([H])C(C([H])([H])[H])(C([H])([H])[H])[C@@]2([H])C([H])([H])C([H])([H])[C@]1(C([H])([H])[H])C2([H])[H]
[H]N1C(=O)C([H])=C(C2=C1C(F)=C([H])C([H])=C2[H])C([H])([H])N(C(=O)C1=C(N=C([H])S1)C([H])([H])[H])C1=C([H])C([H])=C([H])C(Cl)=C1[H]
[H]OC1=C2C([H])=C([H])C([H])=C([H])C2=NN1C([H])([H])C1=C(Cl)N=C([H])C([H])=C1[H]
[H]C1=NC(OC2([H])C([H])([H])C([H])([H])N(C3=C(Cl)C([H])=C([H])C([H])=N3)C([H])([H])C2([H])[H])=C(N=C1[H])C1([H])C([H])([H])C([H])([H])N(C(=O)C([H])([H])[H])C([H])([H])C1([H])[H]
[H]C1=C([H])C([H])=C(OC2=C([H])C([H])=C(C([H])=C2[H])S(=O)(=O)N2C(=O)N(C3=C([H])C([H])=C([H])C([H])=C3[H])C([H])([H])C2=O)C([H])=C1[H]
[H]N(C(=O)C1=C([H])C([H])=C([H])C(=C1[H])C(F)(F)F)C([H])([H])C(=O)N([H])[C@@]1([H])C([H])([H])C([H])([H])[C@@]([H])(N(C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])[C@@]1([H])C([H])([H])S(=O)(=O)C1=C([H])C([H])=C(SC([H])([H])[H])C([H])=C1[H]
[H]OC([H])([H])C([H])([H])N([H])C([H])([H])C1=NN=C2N1C([H])=C([H])C1=C2C([H])=C(C2=C([H])C([H])=C([H])C([H])=C2[H])C(=N1)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1C([H])([H])C([H])([H])C([H])(C2=NN([H])C(=N2)C2=NC([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]C1=C([H])C2=NC(=C([H])C([H])=C2C([H])=C1[H])C1=NOC(=N1)C1([H])C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2Cl)C([H])([H])C1([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C(N([H])C2=C([H])C([H])=NC([H])=N2)C([H])=C1[H])C1=NC(=C([H])S1)C1=C(Cl)C(Cl)=C([H])C([H])=C1[H]
[H]OC([H])([H])C([H])([H])N([H])C(=O)C1=C([H])C(N([H])C2=NC([H])=NN3C([H])=C(C(=O)C4=C([H])C([H])=C([H])C([H])=C4[H])C(=C23)C([H])([H])[H])=C(C([H])=C1[H])C([H])([H])[H]
[H]N(C(=O)OC1([H])C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])[C@]([H])(C(=O)N([H])[C@@]([H])(C([H])([H])[H])C([H])([H])N([H])C1=C([H])C([H])=C(OC(F)(F)F)C([H])=C1[H])C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
COC1=CC2=C(CN(C[C@]3(CC(=O)NC3=O)C#CC3=CC=CN=C3C3=C(C)N(C)N=C3C)C2=O)C=C1
[H]C1=C([H])C(=C([H])C([H])=C1Cl)[C@]1([H])C([H])([H])[C@]2([H])N(C([H])([H])[H])[C@@]([H])(C([H])([H])C2([H])[H])[C@]1([H])C(=O)N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]C1=C([H])C(=C([H])C([H])=C1OC([H])([H])[H])N1C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])C([H])([H])N2C(=O)C([H])([H])C3(C([H])([H])C([H])([H])C([H])([H])C3([H])[H])C([H])([H])C2=O)C([H])([H])C1([H])[H]
[H]N(C(=O)C([H])([H])[H])C1=NC2=C(C([H])=C([H])C([H])=N2)N2C(=O)N(N=C12)C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]OC1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[C@]1([H])N([H])C(=O)[C@]([H])(N([H])C(=O)C(=O)[C@@]([H])(N([H])C(=O)[C@@]2([H])N(C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)C3=C([H])C([H])=C([H])C([H])=C3[H])C([H])([H])[H])C([H])([H])N([H])C(=O)\C([H])=C1/[H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=N[H])N([H])[H])[C@@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])[H]
[H]N1[C@]2([H])C([H])([H])C([H])([H])[C@@]1([H])[C@]([H])(C(=O)OC([H])([H])[H])[C@@]([H])(C1=C([H])C([H])=C(F)C([H])=C1[H])C2([H])[H]
[H]OC([H])([H])C1=C([H])C([H])=C2C(=C1[H])C1=C(OC2(C([H])([H])[H])C([H])([H])[H])C([H])=C(C([H])=C1[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]C#CC([H])([H])C([H])([H])C([H])([H])C([H])([H])OC1=C(OC([H])([H])[H])C([H])=C2N=C([H])N=C(N([H])C3=C([H])C(Cl)=C(F)C([H])=C3[H])C2=C1[H]
[H]N(C1=C2N=C(N=C2C2=C([H])C([H])=C([H])C([H])=C2N1[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H]
[H]C1=C([H])C(=C([H])C([H])=C1C([H])([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])S(=O)(=O)N1C([H])([H])[C@@]2([H])N(C([H])([H])[H])C([H])([H])[C@]1([H])C2([H])[H]
[H]C1=C([H])C(=C([H])C(=C1[H])N1C(=O)[C@@]2([H])[C@@]3([H])O[C@]([H])(C([H])([H])C3([H])[H])[C@@]2([H])C1=O)C(F)(F)F
[H]OC([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])(N(C(=O)N([H])C([H])([H])C2=C([H])C([H])=C(F)C([H])=C2[H])C2([H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])[H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]N([H])C1=C2C(SC(=C2C2=C([H])C([H])=C(N([H])C(=O)N([H])C3=C([H])C([H])=C(C([H])=C3[H])C(F)(F)F)C([H])=C2[H])C([H])([H])[H])=NC([H])=N1
[H]N1C2=C([H])C([H])=C([H])C([H])=C2C2=C1C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C3=C([H])C([H])=C([H])C(=C3[H])C(F)(F)F)C([H])([H])C1([H])[H])C([H])([H])C2([H])[H]
[H]N(C(=O)C1=C(F)C([H])=C([H])C(F)=C1[H])C1=C([H])C2=C(C([H])=C1[H])C(=C([H])C(=O)O2)C([H])([H])[H]
[H]N(C(=O)C([H])([H])N(C([H])([H])[H])C([H])([H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])[C@]([H])(C(=O)N([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(OC(=O)C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])=C1[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])OC1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C([H])([H])[H]
[H]OC1=C(N([H])C2=C([H])C([H])=C([H])C([H])=C2[H])\C(=N\C2=C([H])C([H])=C([H])C([H])=C2O[H])C1=O
[H]C1=NSC(=C1[H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C([H])([H])[H]
[H]N([H])C(=O)C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C(=NC(OC([H])([H])[H])=N1)N([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
CN1C=C(C=N1)C1=CC2=C(C=CC3=C(C=C(CC(=O)NCC4=CC=CC=C4)C=C3)C2=O)N=C1
[H]N(N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C(=O)N([H])C1=C([H])SC(=N1)C([H])([H])C1=C(Cl)C([H])=C([H])C([H])=C1Cl
[H]O[C@]([H])(C1=C([H])C([H])=C([H])N=C1[H])C([H])([H])N([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C(N([H])S(=O)(=O)C2=C([H])C([H])=C(C([H])=C2[H])C2=NOC(=N2)C([H])([H])C([H])([H])OC2([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])=C1[H]
[H]N([H])C(=O)C([H])([H])[S@@](=O)C([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C1=C(Cl)C(C(=O)C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H])=C(Cl)C([H])=C1SC([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]C1=NC(OC2=C(C3=C([H])C([H])=C(C([H])=C3[H])S(=O)(=O)C([H])([H])[H])C(OC2=O)(C([H])([H])[H])C([H])([H])[H])=C([H])C([H])=C1Cl
[H]N(C(=O)N([H])C1=C(SC(=C1[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C(=O)OC([H])([H])[H])C1=C([H])C([H])=C(S1)C([H])([H])[H]
[H]N1N=C([H])C(=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])N=C2N([H])C(=O)N(C2=N1)C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N([H])C([H])([H])C1=C2N([H])C([H])=NC2=C([H])C([H])=C1C1=C(Cl)C([H])=C(Cl)C([H])=C1[H]
[H]OC(=O)[C@@]1([H])C([H])([H])N(C([H])([H])C([H])([H])ON=C(C2=C([H])C([H])=C([H])C([H])=C2[H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C1([H])[H]
[H]OC1=C([H])C(=C([H])C([H])=C1[H])N1C(=O)N(C([H])([H])C([H])([H])N2C([H])([H])C([H])([H])C([H])(C([H])([H])C2([H])[H])C(F)(F)F)C([H])([H])C1([H])[H]
[H]O[C@@](C(=O)N1C([H])([H])C([H])([H])[C@@]([H])(C([H])([H])N([H])[H])C1([H])[H])(C1=C([H])C([H])=C([H])C([H])=C1[H])[C@]1([H])C([H])([H])C([H])([H])C(F)(F)C1([H])[H]
[H]N1C(=NN=C1C1([H])C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C(C([H])=C2[H])C2=NC3=C(C([H])=NC(=N3)N3C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H])C([H])([H])C3([H])[H])C([H])=C2C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H])C1=C([H])N([H])C(=O)C([H])=C1[H]
[H]C1=NN2C([H])=C(C([H])=NC2=C1C1=C([H])C([H])=C(F)C([H])=C1[H])C1=C([H])C([H])=NC([H])=C1[H]
[H]C1=C([H])C([H])=C(OC2=C([H])C(=NC3=C2C([H])=C([H])C(=N3)C([H])([H])[H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])=C1[H]
[H]OC(=O)[C@]([H])(N1C([H])([H])[C@]([H])(C2=C([H])C(F)=C([H])C([H])=C2[H])[C@@]([H])(C([H])([H])N2C([H])([H])C([H])([H])C([H])(C3=C([H])C(=NN3C([H])([H])C([H])([H])[H])C([H])([H])C3=C([H])C4=C(OC([H])([H])O4)C([H])=C3[H])C([H])([H])C2([H])[H])C1([H])[H])[C@@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])[H]
[H]N([H])C([H])([H])C([H])([H])C(=O)N([H])[C@@]([H])(C(=O)N1C([H])([H])C([H])([H])N(C2=NC([H])=C([H])C([H])=C2C([H])([H])N([H])C(=O)C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C(Cl)C([H])=C1Cl
[H]C1=C(SN=C1C([H])([H])[H])C1=NN2C(=NN=C2C([H])([H])OC2=C([H])C([H])=NC3=C2C([H])=C([H])C(OC([H])([H])[H])=C3[H])C([H])=C1[H]
[H]C1=C([H])C(=C(C([H])=C1F)C([H])([H])[H])[C@@]1([H])C([H])([H])N(C(=O)C2([H])C([H])([H])C([H])([H])N(C(=O)C([H])([H])[H])C([H])([H])C2([H])[H])C([H])([H])C([H])([H])[C@]1([H])C(=O)N(C([H])([H])[H])C([H])([H])C1=C([H])C(=C([H])C(=C1[H])C(F)(F)F)C(F)(F)F
[H]N(C(=O)C([H])([H])SC([H])([H])C1=C(OC(=N1)C1=C([H])C([H])=C(OC([H])([H])C([H])([H])[H])C([H])=C1[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])O1
[H]OC1=C([H])C([H])=C(C([H])=C1[H])[C@@]1([H])C([H])([H])C([H])([H])[C@]([H])(N([H])C(=O)[C@]2([H])N([H])C([H])([H])C3=C(C([H])=C([H])C([H])=C3[H])C2([H])[H])C([H])([H])C1([H])[H]
[H]N1C(=NC2=C([H])C(OC3=C([H])C([H])=C(C([H])=C3[H])S(=O)(=O)C([H])([H])C([H])([H])[H])=C(C([H])=C12)C([H])([H])N1C([H])=NC([H])=C1[H])C1=NC([H])=C([H])C([H])=C1[H]
[H]O[C@@]([H])(C([H])([H])N1N=C(C2=C1C([H])([H])C([H])([H])N(C2([H])[H])S(=O)(=O)C([H])([H])[H])C1=C([H])C(SC([H])([H])C([H])([H])N([H])C(=O)[C@@]2([H])C([H])([H])N([H])C([H])([H])C([H])([H])C2([H])[H])=C(C([H])=C1[H])C(F)(F)F)C([H])([H])N1C([H])([H])C([H])([H])C([H])(N2C(=O)C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]N(C(=O)C#CC([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C1=NC([H])=C2N=C([H])N=C(N([H])C3=C([H])C(Cl)=C(F)C([H])=C3[H])C2=C1[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C(=O)C1=C([H])C([H])=C(OC([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N2C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])=C1[H]
[H]C1=C([H])C([H])=C2C([H])=NC(=C([H])C2=N1)C1=C([H])C(F)=C([H])C(C#N)=C1[H]
[H]N(C(=O)C([H])([H])[H])C([H])([H])C([H])([H])N([H])C1=NC(=NC2=C([H])C([H])=C(Cl)C([H])=C12)N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H]
[H]C1=C([H])C(OC2=C(C([H])=NC(=C2[H])C([H])([H])[H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H])=C(SC([H])([H])[H])C([H])=C1[H]
[H]C1=C(OC(=O)C([H])([H])[H])C2=C3C(=C1[H])C([H])([H])[C@]1([H])[C@]4([H])C([H])=C([H])[C@]([H])(OS([O-])(=O)=O)[C@]([H])(O2)[C@]34C([H])([H])C([H])([H])[N+]1(C([H])([H])[H])C([H])([H])[H]
[H]C1=C(N=C(S1)C([H])([H])[H])C#CC1=C([H])\C(=N\OC([H])([H])C([H])([H])OC([H])([H])C([H])([H])F)C([H])([H])C([H])([H])C1([H])[H]
[H]OC(=O)C1=C([H])C(=C([H])C([H])=C1[H])N1C([H])=C([H])C([H])=C1\C([H])=C1/SC(=O)N(C1=O)C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1F
[H]OC([H])([H])C([H])([H])N([H])C(=O)N([H])[C@]12C([H])([H])C([H])([H])[C@@]([H])(C(=C([H])[H])C([H])([H])[H])[C@]1([H])[C@@]1([H])C([H])([H])C([H])([H])[C@]3([H])[C@@]4(C([H])([H])[H])C([H])([H])C([H])([H])[C@]([H])(O[H])C(C([H])([H])[H])(C([H])([H])[H])[C@]4([H])C([H])([H])C([H])([H])[C@@]3(C([H])([H])[H])[C@]1(C([H])([H])[H])C([H])([H])C2([H])[H]
[H]\C(=C(\[H])C1=C([H])C([H])=C(F)C([H])=C1[H])C1=C([H])C([H])=C(C([H])=N1)[S@@](=O)C1=C([H])C([H])=C([H])C([H])=C1F
[H]N([H])C([H])([H])C([H])([H])C(=O)N([H])[C@]([H])(C1=C([H])C(F)=C([H])C([H])=C1N1C([H])([H])C([H])([H])N(C(=O)C([H])([H])C([H])([H])C2=C(Cl)C([H])=C(Cl)C([H])=C2[H])C([H])([H])C1([H])[H])C([H])([H])OC([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC(=O)C1=C([H])C([H])=C2C3=NN(C4=C([H])C([H])=C(C#N)C(Cl)=C4[H])[C@]([H])([C@@]3([H])C([H])([H])C([H])([H])C2=C1[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]OC1=C(C(Cl)=C([H])C([H])=C1N([H])C(=N\C#N)\N([H])C1=C(F)C([H])=C([H])C([H])=C1[H])S(=O)(=O)N(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)C(\[H])=C(/[H])C1=C2C(=C([H])C([H])=C1[H])N(C([H])=C2C([H])([H])C1=C([H])C2=C(C([H])=C([H])C([H])=C2[H])C([H])=C1[H])C([H])([H])[H])S(=O)(=O)C1=C([H])C(Cl)=C(Cl)S1
[H]N1C(=O)N([H])C(N2C([H])([H])C([H])([H])C([H])(C3=C([H])C([H])=C([H])C([H])=C3[H])C([H])([H])C2([H])[H])=C(C1=O)C([H])([H])C1=C([H])C(Cl)=C([H])C([H])=C1[H]
[H]N([H])C(=NC([H])([H])C([H])([H])C([H])([H])N(C(=O)[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)C([H])([H])N([H])C(=O)[C@@]([H])(N([H])C(=O)C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C(=O)N(C([H])([H])C(=O)N([H])C([H])([H])C(=O)N([H])[H])C([H])([H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H])N([H])[H]
[H]C1=C([H])C(=C([H])O1)C(=O)N(C1=C([H])C([H])=NC([H])=C1[H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]OC(=O)[C@]([H])(\N=C(/S[H])N([H])C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)N([H])[H])C([H])([H])S[H]
[H]N(C(=O)C([H])([H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H])C1=C([H])C2=C(C([H])=C1[H])C1=C3C(C([H])=C([H])C([H])=C3C2=O)=C([H])C([H])=N1
[H]N(C(=O)OC1([H])C([H])([H])C([H])([H])N([H])C([H])([H])C1([H])[H])C1=C(C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]O[C@]1([H])C([H])([H])S[C@@]([H])(N2C([H])=NC3=C2N=C(N=C3N([H])[H])C#CC([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])[C@]1([H])O[H]
[H]OC([H])([H])[C@@]1(OC(=O)\C(=C(\[H])C2=C([H])C([H])=C(Cl)C([H])=C2[H])C1([H])[H])C([H])([H])OC(=O)C([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C1=C([H])C(OC([H])([H])[H])=C(Cl)C([H])=C1Cl)C1=C(C#N)C([H])=NC2=C([H])C([H])=C(C([H])=C12)C1=C([H])C([H])=C(C([H])=N1)C([H])([H])N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N([H])C(=NC(=O)C1=C(C([H])=C(O1)C1=C(OC([H])([H])[H])C([H])=C([H])C(Cl)=C1[H])N(C([H])([H])[H])C([H])([H])[H])N([H])[H]
[H]N(C(=O)C1=C([H])N=C2C([H])=C([H])C([H])=C([H])C2=C1C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1C2=C(N=C1C([H])([H])C([H])([H])C([H])([H])[H])C(=C([H])C(=N2)C([H])([H])[H])C([H])([H])[H])S(=O)(=O)C1=C([H])C([H])=C(C([H])=C1[H])[N+]([O-])=O
CN1CCN(CCCNC(=O)C2=C(C)N(C(=C2)C2=CC=C(C=C2)C2=CC=CC=C2)C2=CC=C(C=C2)S(N)(=O)=O)CC1
[H]N([H])C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)N([H])C1=NC(=NC(N([H])C([H])([H])[H])=C1[H])N([H])C([H])([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])N1C([H])([H])C([H])([H])N(C(=S)SSC(=S)N2C([H])([H])C([H])([H])N(C3=C([H])C([H])=C([H])C([H])=C3[H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]OC(=O)C([H])([H])[C@]([H])(N([H])C(=O)C([H])([H])N1C(=O)N([H])[C@]([H])(C1=O)C([H])([H])C([H])([H])C([H])([H])N([H])C(=N[H])N([H])[H])C(=O)N([H])[C@]([H])(C(=O)O[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C1=C([H])C(Br)=C([H])C([H])=C1[H])C1=NC([H])=NC2=C1C1=C(C([H])=C([H])C([H])=C1[H])N2C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H]
[H]C1=C([H])C(=C([H])C([H])=C1Br)C1=C(C(=O)OC([H])([H])[H])[C@@]2([H])O[C@]([H])(C([H])([H])C2([H])[H])C1([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C1=NOC(=N1)[C@@]1([H])[C@]2([H])N(C([H])([H])[H])[C@@]([H])(C([H])([H])C2([H])[H])C([H])([H])[C@]1([H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H]
[H]OC(=O)C1=C([H])N=C(C([H])=C1[H])N(C1=C([H])C(OC([H])([H])C(=C([H])[H])C([H])([H])[H])=C(C([H])=C1[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])[H]
[H]N1C(=O)C2=C(C3=C1C([H])=C([H])C(OC1([H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])OC([H])([H])[H])C([H])([H])C1([H])[H])=C3[H])C([H])([H])C([H])([H])SC2([H])[H]
[H]C1=C(C([H])=C(C(=C1[H])S(=O)(=O)C([H])([H])[H])[N+]([O-])=O)C1=NC(=C(S1)C(=O)N1C([H])([H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])C1([H])[H])C(F)(F)F
[H]C1=C(ON=C1C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1OC([H])([H])C([H])([H])N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H]
[H]C1=C([H])C(C#CC([H])([H])OC2=NSN=C2[C@]23C([H])([H])[N@@]4C([H])([H])[C@@]2([H])[C@@]3([H])C4([H])[H])=C([H])C([H])=C1F
[H]N(C(=O)[C@@]([H])(N([H])C(=N\C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])\N([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C1=C([H])C2=C([H])C([H])=C([H])C([H])=C2C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[P+](C1=C([H])C([H])=C([H])C([H])=C1[H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC1=C([H])C([H])=C(C(O[H])=C1[H])C1=C([H])C(=O)C2=C([H])C([H])=C(O[H])C([H])=C2O1
[H]N(C(=O)C1=C([H])C(OC2=C([H])C3=C(OC(=N3)N([H])C3=C([H])C([H])=C(C([H])=C3[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])=C2[H])=C([H])C([H])=N1)C([H])([H])[H]
[H]N(C1=NC([H])=NC2=C1SC(C#C[C@@]1([H])N([H])C([H])([H])[C@]([H])(OC(=O)C([H])([H])C([H])([H])[H])C1([H])[H])=C2[H])C1=C([H])C([H])=C(OC([H])([H])C2=C([H])C([H])=C([H])C(F)=C2[H])C(Cl)=C1[H]
[H]OC(=O)[C@]([H])(N([H])C(=O)[C@]([H])(C([H])([H])S[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])SC([H])([H])C1=C([H])C(=C(C([H])=C1[H])C([H])([H])[H])C([H])([H])[H]
[H]OC([H])([H])[C@](N([H])[H])(C([H])([H])OP(=O)(O[H])O[H])C([H])([H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C(OC2=C([H])C([H])=C(C([H])=C2[H])C([H])([H])[H])C([H])=C1[H]
[H]N(C([H])([H])C(=O)N1[C@]([H])(C#N)C([H])([H])C([H])([H])[C@]1([H])C#N)C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)C1=C([H])C(=C([H])C([H])=C1[H])C(F)(F)F)S(=O)(=O)C1=C([H])C([H])=C([H])C([H])=C1C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1C(=O)N(N=C1C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1C(F)(F)F
[H]C1=NC2=C(OC3=C([H])C([H])=C(Cl)C([H])=C23)C(=N1)N1C([H])([H])C([H])([H])N(C([H])([H])[H])[C@]([H])(C([H])([H])[H])C1([H])[H]
[H]N(N(C(=O)OC([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C(=O)C1=C2C([H])=C([H])C([H])=C([H])C2=NC(C2=C([H])C([H])=C([H])C([H])=C2[H])=C1C([H])([H])N1C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])S(=O)(=O)C1=C([H])C([H])=C([H])C([H])=C1[H]
CC1=C(C=NN1C1=CC=CC=C1)C(=O)NCC(O)(CC1(C)CCCC2=CC=CC=C12)C(F)(F)F
[H]N([H])C1=NC(=C([H])S1)[C@@]([H])(C(=O)N([H])C([H])([H])C1=C([H])C(=C([H])C(=C1[H])C(F)(F)F)C(F)(F)F)C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])(C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N=C(N([H])[H])C1=C([H])C([H])=C(S1)C([H])([H])N([H])C(=O)C([H])([H])N1C(=O)C(=NC([H])=C1C([H])([H])[H])N([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC1=C(O[H])C([H])=C2C(=C1[H])C([H])([H])C([H])([H])[C@@]1([H])N([H])C([H])([H])C3=C(C([H])=C(C([H])=N3)C([H])([H])[H])[C@]21[H]
[H]N=C(N([H])[H])C1=C([H])C([H])=C2C([H])=C([H])C(=C([H])C2=C1[H])C([H])([H])N(C(=O)C1=C([H])C([H])=C([H])C2=C([H])C([H])=C([H])C([H])=C12)C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@]1([H])C([H])([H])[H]
[H]N1C([H])([H])C([H])([H])N(C(=O)C2=C(OC3=C([H])C(F)=C([H])C([H])=C3C([H])([H])[H])N(C3=NC([H])=C([H])C([H])=C23)C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]OC(=O)C1=C(N([H])C(=O)C([H])([H])C([H])([H])C2=C3C([H])=C([H])C4=C([H])C(O[H])=C([H])C([H])=C4N3N=N2)C([H])=C([H])C([H])=C1[H]
[H]OC(=O)C([H])([H])[C@@]([H])(N([H])C(=O)[C@]1(N(C([H])([H])C1([H])[H])S(=O)(=O)C1=C([H])C(Cl)=C([H])C(Cl)=C1[H])C([H])([H])[H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]N([H])C1=NC2=C([H])C(=C([H])C([H])=C2[C@@]2([H])C([H])([H])C([H])([H])C([H])([H])[C@@]12[H])C([H])([H])C([H])([H])N([H])C([H])([H])C1=C([H])C([H])=C([H])C(Cl)=C1[H]
[H]O[C@@]([H])(C([H])([H])C([O-])=O)C([H])([H])[C@]([H])(O[H])C([H])([H])C([H])([H])C1=C(N(C([H])=C1C1=C([H])C([H])=C(F)C([H])=C1[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N1C(=O)C2=C([H])C([H])=C([H])C3=C2[C@@]([H])(N(C(=O)C([H])([H])C([H])([H])N2C([H])=NC4=C2C([H])=C([H])C([H])=C4[H])C([H])([H])C3([H])[H])C1([H])[H]
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[H]N([H])C(=O)N([H])C1=C([H])C([H])=C2N([H])C(=O)\C(=C(\[H])C3=C([H])C(=C([H])N3[H])C(=O)N3C([H])([H])C([H])([H])[C@]([H])(N(C([H])([H])[H])C([H])([H])[H])C3([H])[H])C2=C1[H]
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[H]N(C(=O)C1=C([H])N(C2=C(N([H])C(=O)C([H])=C2[H])C1=O)C([H])([H])C1=C(Cl)C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
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[H]OC(=O)C1=C([H])C([H])=C([H])C(=C1[H])S(=O)(=O)N1C([H])([H])C2=C(C([H])=C([H])C(I)=C2[H])C([H])([H])C1([H])[H]
[H]N(C(=O)N([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C1=C([H])C(N([H])C2=NC3=C(N=C([H])N3[H])C(=N2)C2=C([H])C([H])=C(OC([H])([H])[H])C([H])=C2[H])=C([H])C([H])=C1[H]
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[H]N([H])C1=C(N([H])C(=O)C2=C([H])C([H])=C(N=C2[H])N2C([H])([H])C([H])([H])N(C(=O)OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])[C@@]([H])(C([H])([H])[H])C2([H])[H])C([H])=C([H])C([H])=C1[H]
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[H]OC1=C([H])C([H])=C(C2=C1N([H])C(=O)S2)[C@@]([H])(O[H])C([H])([H])N([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C(=C1[H])C([H])([H])N([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=N1
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[H]N(C(=O)N([H])[C@]1([H])C([H])([H])C([H])([H])N(C(=O)C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])[C@@]1([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])[C@@]([H])(C([H])([H])C2=C([H])C([H])=C(F)C([H])=C2[H])C1([H])[H])C1=NC(=C(S1)C(=O)C([H])([H])[H])C([H])([H])[H]
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[H]O[C@]1([H])C([H])([H])N(C2=NC([H])=C(N([H])C(=O)C3=C(OC(=N3)C3=C([H])C([H])=C([H])C([H])=C3[H])C(F)(F)F)C([H])=N2)C([H])([H])C1([H])[H]
[H]OC([H])([H])[C@]1([H])N(C(=O)C([H])([H])N2C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])[C@]([H])(C(=N\OC([H])([H])[H])\C([H])([H])OC([H])([H])C3=C([H])C(=C([H])C(=C3[H])C(F)(F)F)C(F)(F)F)C3=C([H])C(Cl)=C(Cl)C([H])=C3[H])C([H])([H])C2([H])[H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
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[H]N([H])C1=C([H])C(=NC2=NC(=NN12)C1=C([H])C([H])=C([H])O1)N([H])C([H])([H])[C@]1([H])N(C([H])([H])C2=C([H])C(Cl)=NC([H])=C2[H])C([H])([H])C([H])([H])C1([H])[H]
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[H]N=C(SC([H])([H])C([H])([H])C([H])([H])C1=C([H])N([H])C([H])=N1)N([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC1=C([H])C([H])=C(C([H])=C1O[H])C([H])([H])[C@@]1([H])N([H])C([H])([H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C12
CCOC1=C(F)C(OC)=NC(=N1)N1C[C@H]2C(=O)N(C)C(=N)N[C@]2(C1)C1=CC=CC=C1
[H]C1=NC(N2C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C2([H])[H])=C(C([H])=C1[H])C1=NC2=C([H])C(OC([H])([H])[H])=C([H])C(=C2C(=O)O1)C([H])(C([H])([H])[H])C([H])([H])[H]
[H]O[C@@]1([H])[C@@]([H])(N([H])C(=O)C([H])([H])N2C(=O)[C@@]([H])(N([H])S(=O)(=O)C3=C([H])C([H])=C([H])C([H])=C3[H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C(=N[H])N([H])[H]
[H]N(C(=O)C([H])([H])C(=O)N([H])C1=C([H])C([H])=C(OC2=C([H])C([H])=NC3=C2SC(=C3[H])C2=C([H])N(C([H])=N2)C([H])([H])[H])C(F)=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
CNC(=O)\C=C1\COC2=CC(OS(=O)(=O)C3=CC=CC(=C3)C#N)=CC=C12
[H]N(C1=C2C(=NC1=O)C([H])=C([H])C(=C2Br)C([H])([H])[H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]N(C1=NC([H])=C(N2C([H])=NC([H])=C12)C1=C([H])C([H])=C(OC([H])([H])[H])C(OC([H])([H])[H])=C1[H])C1=C(C([H])=C([H])C([H])=C1C([H])([H])[H])C([H])([H])[H]
O=C(N1CCN(CC2=CC=C(C=C2)C2=NN=C3N2C2=CC=CN=C2NC2=C3C=CC=C2)CC1)C1=CC=CC=C1
[H]N([C@]([H])(C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)C1=C(C([H])=C(Cl)C([H])=C1[H])C(=O)C1=C([H])C([H])=C(Cl)C([H])=C1[H])C([H])([H])[H])S(=O)(=O)C([H])([H])[H]
[H]O[C@@]1([H])[C@@]([H])(O[C@]([H])(C(=O)N([H])C([H])([H])C([H])([H])[H])[C@@]1([H])O[H])N1C([H])=NC2=C(N=C(N=C12)C#CC1(O[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])N([H])C([H])([H])C([H])([H])[H]
[H]C1=NC(=C([H])C([H])=C1[H])C1(C(=O)N2C([H])([H])C([H])([H])C3(C2([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C3([H])[H])C([H])([H])C1([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])[C@]1([H])C([H])([H])[C@@]1([H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C([H])C([H])=C(Cl)C([H])=C2Cl)C([H])([H])C1([H])[H]
[H]N(C(=O)OC1=C(C([H])=C([H])C([H])=C1[H])C1=C([H])SN=N1)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]C1=C(N=C(S1)N1N=C(C2=C([H])C([H])=C(C(=C2[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])[C@@]1([H])C1=C([H])C([H])=C(F)C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C1=NN(C([H])=C1C([H])([H])[H])C1([H])C([H])([H])C([H])([H])N(C2=NC3=C([H])C([H])=C([H])C([H])=C3N2C([H])([H])C2=C([H])C([H])=C(F)C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N1C([H])([H])C([H])([H])N(C2=C([H])C([H])=C([H])C(SC3=C([H])C([H])=C(OC([H])([H])[H])C([H])=C3[H])=C2[H])C([H])([H])C1([H])[H]
[H]N(C(=O)OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])[C@]([H])(C(=O)OC([H])([H])C1=C(OC([H])([H])[H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H]
[H]O\C(=C(\C#N)C(=O)N([H])C1=C([H])C([H])=C(C([H])=C1[H])C(F)(F)F)C([H])([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C(=O)C1=C([H])C([H])=C([H])C(OC(=O)N2C([H])([H])C([H])([H])[N@]3C([H])([H])C([H])([H])[C@]2([H])C([H])([H])C3([H])[H])=C1[H]
CN(C)CCCOC1=CC=CC=C2C(\C=C3/C(=O)NC4=CC=C(F)C(F)=C34)=CC(C)=C12
[H]N([H])C1=C([H])C2=C(C(=C1[H])C1=C([H])C([H])=C([H])C([H])=C1Cl)C([H])([H])N([H])C(=O)N2C1=C(Cl)C([H])=C([H])C([H])=C1Cl
[H]O[C@]([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])N([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C(C(=O)N([H])S(=O)(=O)C([H])([H])[H])C(OC([H])(C([H])([H])[H])C([H])([H])[H])=C1[H]
[H]SC([H])([H])[C@]([H])(C(=O)N([H])[C@]1([H])C(=O)N([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N2C([H])=C(C3=C2C([H])=C([H])C([H])=C3[H])C1([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H]
COCCNC(=O)C1=CC2=C(NC(=O)C2=C(C2=NC3=CC=CC=C3N2)C2=CC=CC=C2)C=C1
[H]OC1=C([H])C([H])=C(N([H])C(\S[H])=N\C2=C([H])C([H])=C(N([H])C(=O)C3=C(O[H])C([H])=C([H])C([H])=C3[H])C([H])=C2[H])C([H])=C1O[H]
[H]N(C(=O)C([H])([H])[H])[C@@]1([H])C([H])([H])N(C2=NC([H])=C([H])C(=C2[H])C2=C([H])C([H])=C(SC3=C(C([H])=C([H])C([H])=C3[H])C([H])(C([H])([H])[H])C([H])([H])[H])C(=C2[H])C(F)(F)F)C([H])([H])C1([H])[H]
[H]C1=NC([H])=C(N1C([H])([H])C1=C([H])C([H])=C(Br)C([H])=C1[H])C([H])([H])C([H])([H])C(=O)OC([H])([H])[H]
[H]C1=C([H])C(=C([H])C(=C1[H])C(=O)N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C([H])C([H])=C(Cl)C([H])=C2[H])C([H])([H])C1([H])[H]
[H]C1=NC2=C(N=C(C([H])=C2N1C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C1=C([H])C(=C(OC([H])([H])C([H])([H])[H])C([H])=C1[H])C(F)(F)F)C#N
[H]C1=C([H])N2C(=NC(=C2C2=NN(C(=O)C([H])([H])C2([H])[H])C2=C(C([H])=C([H])C([H])=C2[H])C([H])([H])[H])C2=C([H])C([H])=C(F)C([H])=C2Cl)C([H])=C1[H]
CC1=CC(N[C@H](CCCCNCC2=CC=CC(F)=C2)C(=O)NO)=CC(C)=C1F
[H]O[C@]([H])(C1=C([H])C([H])=C([H])N=C1[H])C([H])([H])N([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C(N([H])C(=O)C2=C([H])C([H])=C([H])C([H])=C2N2C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])=C1[H]
[H]OC1=C([H])C(=C([H])C(O[H])=C1[C@]1([H])C([H])=C(C([H])([H])[H])C([H])([H])C([H])([H])[C@@]1([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]\C(=C(\[H])C([H])([H])N(C(=O)C([H])([H])Cl)C1=C([H])C2=C(OC([H])([H])C([H])([H])O2)C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC1=C([H])C([H])=C(\C([H])=C2/SC(=O)N(C2=O)C([H])([H])C(=O)C(F)(F)F)C([H])=C1[H]
CN1N=C(C)C(C(=O)N2CCCCC2C2=CC=CN=C2)=C1OC1=CC(Cl)=CC=C1Cl
[H]N1C(=O)C([H])=C(C2=C([H])C([H])=C(F)C(F)=C12)C([H])([H])N1C2=NC([H])=C([H])N=C2N=C1C1([H])C([H])([H])C([H])([H])C1([H])[H]
[H]OC(=O)[C@]1([H])N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]2([H])N([H])C([H])([H])C([H])([H])[C@]2([H])C2=C([H])C([H])=C(O[H])C([H])=C2[H])C([H])([H])SSC1(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C1=C([H])C([H])=C2C(=O)N(C3=C([H])C([H])=C(OC([H])([H])[H])C([H])=C3[H])C(=NC2=C1[H])C([H])([H])C([H])([H])N1C(=O)C2=C(C1=O)C(OC([H])([H])[H])=C([H])C([H])=C2[H]
[H]N(C(=O)C1=C([H])N(C2=C([H])C([H])=C([H])C(=C2[H])C2=C([H])C([H])=C([H])C(=C2[H])C(=O)C([H])([H])[H])C2=NC([H])=C([H])C([H])=C2C1=O)C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N([H])C1=N[C@@](N(C(=N1)N([H])[H])C1=C([H])C([H])=C(Cl)C([H])=C1[H])(C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C1=C(C([H])=C(C([H])=C1[H])[N+]([O-])=O)S(=O)(=O)N([H])C(=O)N([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C1=C(C([H])=C([H])C([H])=C1C([H])([H])[H])C([H])([H])[H]
[H]N([H])[C@@]1([H])C([H])([H])N(C2=NC3=C(N2C([H])([H])C#CC([H])([H])[H])C(=O)N(C(=O)N3C([H])([H])[H])C([H])([H])C2=C([H])C([H])=C(OC([H])([H])[H])C([H])=C2[H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C(F)C([H])=C1[H])C1=C([H])C([H])=C2N([H])C([H])=C(C2=C1[H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H]
[H]C1=C([H])C([H])=C(N2C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])[C@@]3([H])C4=C([H])C([H])=C([H])C([H])=C4C([H])([H])C([H])([H])C3([H])[H])C([H])([H])C2([H])[H])C(OC([H])([H])[H])=C1[H]
[H]N([H])C(=O)[C@]([H])(N1C(=O)N(C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])[C@@]([H])(C1=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])[H])C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]OC1=C([H])C([H])=C(N([H])C(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])OC2=C(C([H])=C([H])C(O[H])=C2[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])=C1[H]
[H]O[C@@]([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])[C@]([H])(N(C(=O)N([H])C1=C([H])C([H])=C(OC2=C([H])C([H])=C([H])C(=C2[H])[N+]([O-])=O)C([H])=C1[H])C([H])([H])[H])C([H])([H])[H]
[H]N(\C([H])=C1/C(=O)N([H])C2=C([H])C([H])=C([H])C([H])=C12)C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)N([H])C1=NC([H])=C([H])S1
[H]OC(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)C(N([H])C(=O)[C@]([H])(N(C([H])([H])C([H])=C([H])[H])C([H])([H])C([H])=C([H])[H])C([H])([H])C1=C([H])C([H])=C(O[H])C([H])=C1[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)C([H])([H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])C1=C([H])N(C([H])=N1)C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC1=C(C([H])=C([H])C(=C1[H])C([H])([H])[C@@]([H])(C([H])([H])[C@]([H])(N([H])[H])[C@@]([H])(O[H])C([H])([H])[C@]([H])(C(=O)N([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]OC([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@]([H])(C1=C([H])C([H])=C([H])N=C1[H])C1=C(C(=O)C(=C(C1=O)C([H])([H])[H])C([H])([H])[H])C([H])([H])[H]
[H]OC(=O)C1=C([H])C([H])=C2N=C(OC2=C1[H])N([H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C(OC([H])([H])C([H])([H])[H])=C(F)C(OC([H])([H])C([H])([H])[H])=C2[H])C([H])([H])C1([H])[H]
[H]N(C(=O)[C@@]([H])(N1C([H])=C([H])C(=C([H])C1=O)S(=O)(=O)C1([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C1=NN(C([H])=C1[H])C([H])([H])[H]
[H]N(C(=O)[C@@]1([H])C([H])([H])C([H])([H])[C@]([H])(C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C(OC([H])([H])[H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N(C(=O)[C@]1([H])C([H])([H])C2=C(C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C2(N(C3=C([H])C([H])=C([H])C([H])=C3[H])C([H])([H])N([H])C2=O)C([H])([H])C1([H])[H]
[H]O[C@@]1([H])C([H])([H])C([H])([H])[C@]([H])(N([H])C(=O)C2=C([H])C([H])=C(C([H])=C2[H])C([H])([H])C2=C(N(C3=C([H])C([H])=C([H])C([H])=C3[H])C3=NC(=C([H])C([H])=C3C2=O)C([H])([H])[H])C(=O)OC([H])([H])[H])C([H])([H])C1([H])[H]
[H]N(C(=O)[C@@]1([H])C([H])([H])C([H])([H])[C@]2([H])[C@]3([H])C([H])([H])C([H])([H])[C@@]4([H])N([H])C(=O)C([H])=C([H])[C@]4(C([H])([H])[H])[C@@]3([H])C([H])([H])C([H])([H])[C@]12C([H])([H])[H])C1=C([H])C([H])=C([H])C(Br)=C1[H]
[H]N(C1=NN=C(O1)C1=C(N=C([H])N1C([H])([H])[H])N([H])C([H])([H])C1=C([H])C([H])=NC([H])=C1[H])C1=C(F)C([H])=C(C([H])=C1[H])C([H])([H])[H]
[H]N(C(=O)C1=NN=C(O1)N([H])C1=C(F)C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C(OC([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])N=C1[H]
[H]C1=NC2=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C([H])=C2C(=N1)N1C2=C(C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N(C1=C(Br)C(=NO1)C([H])([H])[H])S(=O)(=O)C1=C(C([H])=C([H])S1)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H]
[H]N(N1C2=C([H])C([H])=C(Cl)C([H])=C2N=C(N2C([H])([H])C([H])([H])N(C([H])([H])C3([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C3([H])[H])C([H])([H])C2([H])[H])C2=C1C([H])=C([H])C([H])=C2[H])C(=O)C1=C([H])C([H])=C([H])C([H])=C1Cl
[H]N([H])C1=NC(=NN1C(=O)C1=C([H])C([H])=C(F)C([H])=C1[H])C1=C([H])N=C([H])C([H])=C1[H]
[H]N(C([H])([H])[H])C([H])([H])C([H])([H])[C@@]([H])(C1=C([H])C([H])=C(Cl)C(Cl)=C1[H])C1=C2C([H])=C([H])N([H])C2=C([H])C([H])=C1[H]
[H]N(C(=O)C1=C([H])C(=C([H])C(=C1[H])N1C([H])=NC(=C1[H])C([H])([H])[H])C(F)(F)F)C1=C([H])C([H])=C([H])C(N([H])C2=C([H])C3=C(C([H])=C2[H])\C(=C(/[H])C2=C([H])C([H])=C([H])N2C([H])([H])[H])C(=O)N3[H])=C1[H]
[H]N(C(=O)C([H])([H])[H])C1=C([H])C([H])=C(OC(=O)C2=C([H])C3=C(OC2=O)C([H])=C([H])C(Br)=C3[H])C([H])=C1[H]
[H]OC1=C(Br)C([H])=C(\C([H])=C2/C(=O)N([H])C3=C([H])C([H])=C([H])C([H])=C23)C([H])=C1Br
Cl.CCCCCCN1CCC2(CCC3=CC=CC=C23)CC1
[H]OC1=C([H])C2=C(C([H])=C1O[H])C([H])=C(C([H])=N2)C1=C([H])C([H])=NC([H])=C1[H]
[H]OC(=O)C([H])([H])N([H])C(=O)[C@]([H])(N([H])C(=O)[C@]1([H])N(C(=O)C([H])([H])N([H])C(=O)C([H])([H])N([H])C(=O)C2=C([H])C3=C(C([H])=C2[H])C2=C(C([H])=C([H])C([H])=C2[H])C(=O)C3=O)C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=N[H])N([H])[H]
[H]OC1=C([H])C(O[H])=C(C([H])=C1C([H])([H])C([H])([H])[H])C1=NN([H])C(=C1C1=C([H])C2=C(OC([H])([H])C([H])([H])O2)C([H])=C1[H])C([H])([H])[H]
[H]N([H])C1=NC([H])=NC2=C1N=C(Br)N2C([H])([H])[H]
[H]C1=C(C([H])=C(S1)C(=O)N(C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C(=O)C(F)(F)F
[H]N([H])S(=O)(=O)C1=C(OC([H])([H])[H])C([H])=C([H])C(=C1[H])C([H])([H])[C@]([H])(N([H])C([H])([H])[C@]1([H])OC2=C(O[C@]1([H])C([H])([H])[H])C([H])=C([H])C([H])=C2[H])C([H])([H])[H]
[H]N([H])C1=NN([H])C2=C1C([H])=C([H])C(=C2[H])C1=C([H])C([H])=NC(=N1)N([H])C([H])([H])C([H])([H])[H]
[H]N(C1=C([H])C([H])=C([H])C([H])=C1[H])S(=O)(=O)N1C([H])([H])C([H])([H])C2=C([H])C3=C(C([H])=NN3C3=C([H])C([H])=C(F)C([H])=C3[H])C([H])([H])[C@]2(C([H])([H])C2=C([H])C([H])=C(F)C([H])=C2[H])C1([H])[H]
CC1=CC=C(C=C1)C(SCCN)(C1=CC=CC=C1)C1=CC=CC(O)=C1
[H]N(C(=O)C1=C(N(N=C1C1=NN=C(O1)C1(C([H])([H])C1([H])[H])C(F)(F)F)C1=C([H])C([H])=C(Cl)C([H])=C1Cl)C1=C([H])C([H])=C(Br)C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)[C@@]1([H])N(C(=O)[C@]([H])(N([H])S(=O)(=O)C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C2([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])[C@]1([H])C([H])([H])C2=C([H])N([H])N=C2C([H])([H])C1([H])[H]
[H]OC1=C(O[H])C2=C(C([H])=C1[H])C([H])([H])[C@@]1([H])N(C([H])([H])[H])C([H])([H])C([H])([H])C3=C1C2=C([H])C(SC1=C([H])C([H])=C([H])C([H])=C1[H])=C3[H]
[H]C1=C(OC2=C1C(=C([H])C([H])=C2OC([H])([H])[H])C([H])([H])N1C([H])([H])C2=C(C([H])=C(OC([H])([H])[H])C(OC([H])([H])[H])=C2[H])C([H])([H])C1([H])[H])C(=O)N1C([H])([H])C([H])([H])C([H])(N2C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]N([H])C(=NC([H])([H])C([H])([H])C([H])([H])[C@]([H])(N([H])C(=O)C([H])([H])N(C(=O)[C@]1([H])N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)C([H])([H])[C@]2(SSC1([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C1=C([H])C([H])=C(OC([H])([H])C([H])([H])[H])C([H])=C1[H])[C@@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C(=O)N([H])[H])C([H])([H])C(=O)N([H])[H])C([H])([H])[H])C(=O)N([H])C([H])([H])C(=O)N([H])[H])N([H])[H]
[H]OC(=O)[C@@]1([H])C([H])([H])C([H])([H])[C@]([H])(C([H])([H])N2C3=C(C([H])=C(C([H])=C3[C@@]([H])(N(C3=NN(N=N3)C([H])([H])[H])C([H])([H])C3=C([H])C(=C([H])C(=C3[H])C(F)(F)F)C(F)(F)F)C([H])([H])C([H])([H])C2([H])[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H]
CC(=O)C1=CC(NS(=O)(=O)C2=CC=C(Cl)C=C2Cl)=CC=C1OC1=CC(Cl)=CN=C1
[H]OC1(C2=C([H])C([H])=C([H])C(SC([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H])=N2)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(C(=O)C1=C([H])N(C(=O)C([H])=C1[H])C([H])([H])C([H])([H])OC([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N1N=NC(=N1)C1=C(C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1C(=O)C2=C(N=C1C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])=C([H])C(=C2[H])[N+]([O-])=O
[H]N(OC([H])([H])[H])C(=O)N1C([H])([H])C([H])([H])[C@]([H])(C(=O)N(C([H])([H])[H])C([H])([H])C2=C([H])C(=C([H])C(=C2[H])C(F)(F)F)C(F)(F)F)[C@@]([H])(C2=C(C([H])=C(F)C([H])=C2[H])C([H])([H])[H])C1([H])[H]
[H]N([H])C1=C2C(=NC([H])=N1)N=C(C([H])=C2C1=C([H])C([H])=C(F)C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N=C(N([H])[H])C1=C([H])C([H])=C([H])C(=C1[H])C([H])([H])[C@@]([H])(N([H])S(=O)(=O)C1=C(C([H])=C(C([H])=C1C([H])(C([H])([H])[H])C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])C(=O)N1C([H])([H])C([H])([H])C([H])([H])[C@@]([H])(C(=O)N([H])C([H])([H])[H])C1([H])[H]
[H]O[C@@]([H])(C([H])([H])OC1=C2SC([H])([H])C([H])([H])C([H])([H])C2=C([H])C([H])=C1[H])C([H])([H])N([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]O[C@]([H])(C([H])([H])[C@]([H])(C(=O)N([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])[C@]([H])(N([H])C(=O)C([H])([H])C1=NN=C2N1C([H])=C(N=C2C([H])([H])C([H])([H])C([H])([H])[H])C1=C([H])C([H])=C([H])N=C1[H])C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]C1=C([H])C([H])([H])N(C([H])([H])[C@@]([H])(N(C(=O)C([H])([H])C2=C([H])C([H])=C(C([H])=C2[H])[N+]([O-])=O)C([H])([H])[H])C([H])([H])C([H])([H])SC([H])([H])[H])C1([H])[H]
[H]N([H])C1=C(OC([H])([H])[H])C([H])=C([H])C(=C1[H])N1N=NN=C1C(=O)N([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C(C([H])=C([H])C([H])=C1[H])S(=O)(=O)N([H])[H]
[H]O[C@@]1([H])OC(=O)C([H])([H])[C@]1([H])N([H])C(=O)C([H])([H])N1C(=O)[C@@]([H])(N([H])C(=O)C2=C([H])C([H])=C3C([H])=C([H])C([H])=C([H])C3=C2[H])C([H])([H])N(C(=O)N2C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])C([H])([H])C([H])([H])C1([H])[H]
COC1=CC2=C(CN(C[C@]3(CC(=O)NC3=O)C#CC3=CN=C(N=C3N)N3CCC(=O)CC3)C2=O)C=C1
[H]OC(=O)C([H])([H])OC1=C([H])C(=C([H])C([H])=C1[H])[C@]([H])(OC(=O)[C@@]1([H])N(C([H])([H])C([H])([H])C([H])([H])C1([H])[H])S(=O)(=O)C1=C([H])C2=C(N=C(S2)C([H])([H])[H])C([H])=C1[H])C([H])([H])C([H])([H])C1=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]C1=C(C2=C(C([H])=C([H])C(OC([H])([H])[H])=C2[H])N1S(=O)(=O)C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H]
[H]OC1=C(SC(=N1)C1=C([H])C([H])=C(F)C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C([H])([H])OC1=NO[C@]2(C1([H])[H])C([H])([H])[N@+]1(C([H])([H])[H])C([H])([H])C([H])([H])[C@@]2([H])C1([H])[H]
[H]OC([H])([H])[C@]([H])(N(C1=C(Cl)C([H])=C(C([H])=C1[H])C(O[H])(C(F)(F)F)C(F)(F)F)C([H])([H])C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]O[C@@]([H])(C([H])([H])C(=O)N([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)C([H])([H])C1=C([H])C2=C([H])C([H])=C(C([H])=C2C([H])=C1[H])C(=O)OC([H])([H])C([H])([H])C([H])([H])C(=O)N([H])[C@]([H])(C(=O)N([H])[C@@]([H])(C(=O)N([H])C([H])([H])C([H])([H])C([H])([H])[C@@]([H])(N([H])C1=C([H])C(OC([H])([H])[H])=C([H])C2=C1N=C([H])C([H])=C2[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])[C@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N([H])[C@]([H])(C([H])([H])OC1=C([H])C(=C([H])N=C1[H])C1=C([H])C2=C(N([H])N=C2C([H])([H])[H])C([H])=C1[H])C([H])([H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H]
[H]N(C(=O)N1C([H])([H])C([H])([H])N(C2=NC([H])=NC3=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C([H])=C23)C([H])([H])[C@]1([H])C([H])([H])[H])C1=C([H])C([H])=C(OC2=C([H])C([H])=C([H])C([H])=C2[H])C([H])=C1[H]
[H]N(C(=O)N1C(=O)N(C2=C([H])C([H])=C([H])C([H])=C12)C1([H])C([H])([H])C1([H])[H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N1N=C([H])C(=C1[H])C1=C([H])C2=C(OC(=C2[H])C([H])([H])C([H])([H])N2C([H])([H])C([H])([H])C([H])([H])[C@@]2([H])C([H])([H])[H])C([H])=C1[H]
[H]N(C(=O)OC([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C1=C(C([H])=C([H])C([H])=C1[H])C1=C([H])C(Cl)=C(C([H])=C1[H])[C@@]1([H])C([H])([H])N([H])C([H])([H])C([H])([H])[C@]1([H])C1=C([H])C(=O)N(C([H])=C1[H])C([H])([H])[H]
[H]N(C(=O)C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C(=C([H])C([H])=C1[H])S(=O)(=O)N(C1=C([H])C([H])=C([H])C(Cl)=C1[H])C([H])([H])C(=O)OC([H])(C([H])([H])[H])C([H])([H])[H]
[H]ON([H])C(=O)[C@]([H])(N(C([H])([H])C1=C([H])C2=C(OC([H])([H])O2)C([H])=C1[H])S(=O)(=O)C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])C([H])([H])C([H])([H])N([H])C(=O)C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N([H])C(=NC(=O)C1=C([H])C([H])=C(O1)C1=C(OC([H])([H])[H])C([H])=C([H])C([H])=C1[H])N([H])[H]
[H]N1C(=O)[C@](C(=O)C2=C(Cl)C([H])=C(Cl)C([H])=C12)(C1=C([H])C([H])=C(Cl)C([H])=C1[H])C([H])([H])[H]
[H]N(C(=O)OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])[C@@]1([H])C([H])([H])C([H])([H])[C@]([H])(C([H])([H])N([H])C(=O)C2=C3C([H])=C([H])C([H])=C([H])C3=NC(=C2[H])C2=C(ON=C2C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N1C(=O)C2=C(C1=O)C1=C(C([H])=C([H])C3=C1N(C([H])=C3[H])C([H])([H])[H])C1=C2C2=C(N1[H])C([H])=C([H])C([H])=C2[H]
[H]N1C([H])=C(N2C(Cl)=C(Cl)C([H])=C2C1=O)C([H])([H])C1=C([H])C([H])=C(F)C(=C1[H])C(=O)N1C([H])([H])C([H])([H])C([H])(N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]C1=C(C(=O)C2([H])C(C([H])([H])[H])(C([H])([H])[H])C2(C([H])([H])[H])C([H])([H])[H])C2=C(C([H])=C([H])C([H])=C2[H])N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H]
[H]N1[C@]2([H])C3=C(N(C4=C([H])C([H])=C(C([H])=C34)S(=O)(=O)N3C([H])=C(F)C4=C3C([H])=C([H])C([H])=C4[H])C([H])([H])[H])C([H])([H])[C@@]1([H])C([H])([H])C2([H])[H]
[H]O[C@@]1([H])[C@@]([H])(O[C@]([H])(C(=O)N([H])C([H])([H])[H])[C@]1(O[H])C([H])([H])[H])N1C([H])=NC2=C1N=C(N=C2N([H])C([H])([H])C1=C([H])C(I)=C([H])C([H])=C1[H])N([H])C([H])([H])[H]
[H]N([H])C1=C(N([H])C2=C1C([H])=C(C([H])=C2[H])C([H])([H])[H])C(=O)OC([H])([H])C([H])([H])[H]
[H]N([H])C1=NC(N([H])[H])=C2C(SC3=C2C([H])([H])C([H])([H])C([H])([H])C3([H])[H])=N1
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[H]N(C1=C([H])C2=C(C([H])=C1[H])N(C([H])=C2[H])C([H])([H])[H])C1=C(C#N)C([H])=NC2=C1C([H])=C(S2)C1=C([H])C([H])=C([H])C([H])=C1[H]
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[H]C1=C([H])C(=C([H])C([H])=C1F)C1=C(C(=O)OC([H])([H])[H])[C@]2([H])O[C@@]([H])(C([H])([H])C2([H])[H])C1([H])[H]
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[H]OC(=O)C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C2=C([H])C([H])=C(C(F)=C2N1[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
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CCCCC1=CC2=C(CC(C2)NC[C@H](O)C2=C3C=CC(=O)NC3=C(O)C=C2)C=C1
[H]N1C(=NC2=C1C([H])=C([H])C(=C2[H])C(=O)C([H])([H])C([H])([H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC([H])([H])[C@]1(OC(=O)\C(=C(\[H])C2=C([H])C(=C([H])C([H])=C2[H])C(F)(F)F)C1([H])[H])C([H])([H])OC(=O)C([H])(C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[H]
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[H]OC([H])([H])C1(C2=C([H])C([H])=C(C([H])=C2[H])S(=O)(=O)N2C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C3=C([H])C([H])=NC([H])=C3[H])C([H])([H])[C@@]2([H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C2N(C(=O)OC2=C1[H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
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[H]O[C@]([H])(C(\[H])=C(/[H])C1=C(N(C([H])=C1C1=C([H])C([H])=C(F)C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H])C([H])([H])[C@@]([H])(O[H])C([H])([H])C([O-])=O
[H]N=C(N(C1=C([H])C([H])=C([H])C(=C1[H])C([H])([H])C([H])([H])[H])C([H])([H])[H])N(C1=C(Br)C([H])=C([H])C(Br)=C1[H])C([H])([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])OC(=O)C1=C([H])C2=C(C([H])=C1[H])N1C(=C(C(=O)C([H])([H])C1([H])[H])C([H])([H])[H])C([H])([H])C2([H])[H]
[H]OC([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C(\C([H])=C(/[H])C3=C([H])N=C([H])C(C#N)=C3N([H])C3=C([H])C([H])=C4N([H])C([H])=C([H])C4=C3C([H])([H])[H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]C1=C([H])C(=C([H])C(=C1[H])C1=C([H])C2=C(C([H])=C1[H])[C@]1([H])C([H])([H])C([H])([H])[C@]3([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[C@]13C([H])([H])C2([H])[H])C(=O)C([H])([H])[H]
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[H]OC1=C([H])C([H])=C2N([H])C(=NC2=C1[H])C(=O)N1C([H])([H])C([H])([H])C([H])(OC2=C([H])C([H])=C(Cl)C([H])=C2[H])C([H])([H])C1([H])[H]
[H]OC(=O)C([H])([H])[C@]1([H])C2=C(C3=C([H])C(F)=C([H])C(=C3N2C([H])([H])C2=C([H])C([H])=C(Cl)C([H])=C2[H])S(=O)(=O)C([H])([H])[H])C([H])([H])C1([H])[H]
[H]OC([H])([H])[C@]([H])(O[H])C([H])([H])N1C([H])([H])C([H])([H])C([H])(N(C(=O)N([H])C([H])([H])C2=C([H])C([H])=C(F)C([H])=C2[H])C2=C([H])C([H])=C(Cl)C([H])=C2[H])C([H])([H])C1([H])[H]
[H]C1=C([H])C([H])=C(O1)C([H])([H])C1=C([H])C([H])=C(OC([H])([H])C([H])([H])N2C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])=C1[H]
[H]N(C(=O)C1=C([H])C([H])=C([H])C2=C([H])C([H])=C([H])C([H])=C12)[C@]([H])(C(=O)OC([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])[N+]([O-])=O
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[H]O[C@]([H])(C1=C([H])C([H])=C([H])N=C1[H])C([H])([H])N([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C(N([H])S(=O)(=O)N2C([H])([H])C([H])([H])C([H])(C3=C([H])C([H])=C([H])C([H])=C3[H])C([H])([H])C2([H])[H])C([H])=C1[H]
[H]N1C([H])([H])C([H])(OC2=C(C([H])=C([H])C(Cl)=C2[H])C2=C([H])C([H])=C(C(=C2[H])C([H])([H])[H])C([H])([H])[H])C1([H])[H]
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[H]N(C(=O)[C@@]1([H])N2C(=O)C([H])([H])N(C([H])([H])[C@]2([H])C([H])([H])C1([H])[H])S(=O)(=O)C([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C2N([H])C([H])=NC2=C1[H]
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[H]N1C(=S)S\C(=C(/[H])C2=C([H])C([H])=C(C([H])=C2[H])N(C2=C([H])C([H])=C(OC([H])([H])C([H])([H])[H])C([H])=C2[H])C([H])([H])[H])C1=O
[H]OC(=O)C(=C(/C(=O)C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])\C1=C([H])C2=C(OC([H])([H])O2)C(OC([H])([H])[H])=C1[H]
[H]OC([H])([H])C1=C(OC([H])([H])[H])C([H])=C([H])C(=C1[H])C1=C([H])C([H])=C2C(N=C(N=C2N2C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])N2C([H])([H])[C@@]([H])(O[C@]([H])(C([H])([H])[H])C2([H])[H])C([H])([H])[H])=N1
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[H]N(C(=O)C1=C([H])C(OC2=C([H])C3=C(OC(=N3)N([H])C3=C([H])C([H])=C(Br)C([H])=C3[H])C([H])=C2[H])=C([H])C([H])=N1)C([H])([H])[H]
[H]N(C(=O)C1=C([H])N=C([H])N(C1=O)C([H])([H])C1=C([H])C([H])=C(F)C(F)=C1[H])C([H])([H])C#CC1=C([H])C([H])=C2N=C([H])C(=C([H])C2=C1[H])C(=O)N([H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]OC([H])([H])[C@@]1([H])O[C@@]([H])(N2C([H])=NC3=C(N=C([H])N=C23)N([H])C([H])([H])C([H])([H])C([H])(C2=C([H])C([H])=C([H])C([H])=C2[H])C2=C([H])C([H])=C([H])C([H])=C2[H])[C@]([H])(O[H])[C@]1([H])O[H]
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[H]N1C(=O)N([H])C2(C3=C([H])C(=C([H])C([H])=C13)C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H]
CC1=CC=CC(F)=C1NC(=O)C1=NC2=C(NS(C)(=O)=O)C=CC=C2C(O)=C1
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OC(=O)C1=C2OC3=C(C=C(C=C3)C3=CSC(=N3)C3=CC=CC(I)=C3)C2=CC=C1
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CCC(=O)N1CCC(CC1)NC(=O)NC1=CC=C(Cl)C=C1
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[H]N([H])C1=NC([H])=NC2=C1C(=C(Cl)N2C1([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C(OC2=C([H])C([H])=C([H])C([H])=C2[H])C([H])=C1[H]
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[H]OC(=O)C(\[H])=C(/[H])C1=C([H])C([H])=C(N([H])C(=O)C2(N([H])C(=O)C3=C([H])C4=C(C([H])=C3[H])C(=C(N4C([H])([H])[H])C3=C([H])C([H])=C([H])C([H])=N3)C3([H])C([H])([H])C([H])([H])C([H])([H])C3([H])[H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])=C1[H]
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[H]OC([H])([H])C1=C(C([H])=C([H])C([H])=C1C1=C([H])N(C(=O)C(=N1)N([H])C1=C([H])C([H])=C(C([H])=C1[H])C(=O)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C([H])([H])[H])N1C(=O)C2=C(C([H])=C(C([H])=C2[H])C2(F)C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
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[H]N([H])C1=C2C([H])=C(C(=NC2=NC([H])=N1)C1=C([H])C([H])=C(C([H])=C1[H])N(C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C(OC([H])([H])[H])C(OC([H])([H])[H])=C1[H]
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[H]N(C(=O)N([H])C1=C([H])C([H])=C([H])C([H])=C1OC1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C(=C1[H])C1=C([H])N([H])C2=NC([H])=C(C([H])=C12)C1=C([H])C([H])=C([H])C([H])=C1[H]
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[H]N(C(=O)C([H])([H])C([H])([H])C([H])([H])C(\[H])=C(\[H])C([H])([H])C(\[H])=C(\[H])C([H])([H])C(\[H])=C(\[H])C([H])([H])C(\[H])=C(\[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])F
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[H]N1C(=NC2=C1C([H])=C(C([H])=C2[H])C([H])([H])[H])C(\C#N)=C(\[H])C1=C(OC([H])(C([H])([H])[H])C([H])([H])[H])C([H])=C(C([H])=C1[H])N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H]
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[H]N([H])C([H])([H])C([H])([H])N([H])C(=O)C([H])([H])OC1=C([H])C([H])=C(C([H])=C1[H])C1=NC2=C(N1[H])N([H])C(=O)N(C2=O)C([H])([H])C([H])([H])C([H])([H])[H]
[H]C1=NC([H])=C([H])C(=C1[H])C([H])([H])C(=O)N1C([H])([H])C([H])([H])C(=C2C3=NC([H])=C(SC([H])([H])[H])C([H])=C3C([H])([H])C([H])([H])C3=C2C([H])=C([H])C(Cl)=C3[H])C([H])([H])C1([H])[H]
CN(C1=CC=NC(NC2=CC=CC(=C2)S(C)(=O)=O)=N1)C1=C2OCOC2=CC=C1Cl
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[H]OC1(C2=C([H])C(F)=C([H])C(OC([H])([H])C3=C([H])C([H])=C(C([H])=C3[H])N3C([H])=C([H])N=C3C([H])([H])[H])=C2[H])C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]N(C(=O)C1=C([H])C(Cl)=C([H])C([H])=C1[H])C1=C([H])C(C(=O)N([H])C2=C([H])N=C([H])C([H])=C2[H])=C(Cl)C([H])=C1[H]
[H]N([H])C1=N[C@@](C(=O)N1C([H])([H])[H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C(Cl)=C([H])C([H])=C1[H]
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OC1=C(Br)C=C(\C=N\NC(=O)C2=CC=C(C=C2)C2=CC=NC=C2)C(O)=C1Br
[H]N(C1=NOC(=C1SC1=C([H])C(OC([H])([H])[H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C(=O)OC([H])([H])[H])S(=O)(=O)C1=C([H])C([H])=C(C([H])=C1[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]OC(=O)[C@@]1([H])C([H])([H])[C@]1([H])C1=C([H])C(=C(C([H])=C1[H])C1=NOC(=N1)C1=C([H])C(=C(OC([H])(C([H])([H])[H])C([H])([H])[H])C([H])=C1[H])C(F)(F)F)C([H])([H])[H]
[H]OC1=C([H])C([H])=C(C([H])=C1OC([H])([H])[H])C([H])(N1N=C([H])N=C1[H])C1=C([H])C(OC([H])([H])[H])=C(O[H])C([H])=C1[H]
[H]C1=C([H])C([H])=C([H])C(=N1)N1C([H])([H])C([H])([H])C([H])(C([H])([H])C1([H])[H])C1([H])C([H])([H])C([H])([H])N(C(=O)OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]OC(=O)C([H])([H])[C@]1([H])N([H])C2=C([H])C([H])=C(C([H])=C2C([H])([H])N(C1=O)C([H])([H])[H])C(=O)N([H])C([H])([H])C1=C([H])C2=C(N1[H])C([H])=C([H])C([H])=C2[H]
[H]\C(=C(\[H])[C@]1([H])[C@]2([H])[C@]([H])(OC(=O)[C@]2([H])C([H])([H])[C@]2([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@@]12[H])C([H])([H])[H])C1=C([H])C([H])=C2C([H])=C([H])C(=C([H])C2=N1)C([H])([H])[H]
[C-]#[N+]C1(CCN(CC2=CC=C(C=C2)C2=NN=C3N2C2=CC=CN=C2NC2=C3C=CC=C2)CC1)C1=CC=CC=C1
[H]N(C(=O)OC([H])([H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])S(=O)(=O)C1=C([H])C([H])=C([H])C([H])=C1C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1C(=NC(=C1C(=O)C([H])([H])C([H])([H])N(C(=O)C1=C([H])N=C([H])C([H])=C1[H])C1=C([H])N=C([H])C([H])=C1[H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]OC1=C([H])C([H])=C2N(C3=C(C2=C1[H])C1=C(C(=O)N([H])C1=O)C(=C3[H])C1=C(Cl)C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])N([H])C([H])([H])[H]
[H]N1C([H])=C(C2=C([H])C([H])=C([H])N=C12)S(=O)(=O)C1=C([H])C([H])=C([H])C([H])=C1[N+]([O-])=O
[H]C1=NC2=C([H])C([H])=C(C([H])=C2C([H])=C1[H])C([H])([H])C1=NN=C2N=C([H])C(=NN12)C1=C([H])C([H])=C(F)C([H])=C1[H]
O=C(NC1=C(N=CC=C1)C(=O)NCC1CCOCC1)C1=C2N=CC=NC2=CC=C1
[H]N=C(SC([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])SC(=N[H])N([H])[H])N([H])[H]
[H]C1=C([H])C(OC2=C([H])C(=C(C#N)C([H])=C2[H])C(F)(F)F)=C(OC([H])([H])[H])C([H])=C1[H]
[H]O[C@@](C([H])([H])N([H])C(=O)C1=C(N([H])[H])N(N=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H])(C([H])([H])N(C([H])([H])C([H])([H])[H])S(=O)(=O)C1=C([H])C([H])=C(F)C([H])=C1[H])C(F)(F)F
[H]N(C(=O)N([H])C1=C([H])C([H])=C(C([H])=C1[H])C(F)(F)F)C1=C([H])C([H])=C(OC([H])([H])C([H])([H])C([H])([H])N2C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])C([H])=C1[H]
[H]N([H])C1=C([H])C(=C([H])C([H])=C1C(=O)C1=C(C([H])=C([H])C([H])=C1[H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H]
[H]N(\N=C(/[H])C1=C([H])C([H])=C([H])S1)C1=NC(=C([H])S1)C1=C([H])C([H])=C([H])C(OC([H])([H])[H])=C1[H]
[H]N(C(=O)C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H])C1=C([H])C([H])=C([H])C2=C1C(=O)C1=C([H])C([H])=C([H])C(N([H])C(=O)C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H])=C1C2=O
[H]O[P@@](=O)(OC([H])([H])[H])[C@]([H])(N([H])S(=O)(=O)C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])N([H])C(=O)C1=C([H])C([H])=C(OC([H])([H])C([H])([H])C2([H])C([H])([H])C([H])([H])N([H])C([H])([H])C2([H])[H])C([H])=C1[H]
[H]OC(=O)C1=C([H])C2=C([H])C(Br)=C([H])C(C(=O)N([H])C3([H])C([H])([H])C([H])([H])N([H])C([H])([H])C3([H])[H])=C2O1
[H]OC(=O)C([H])([H])C1=C([H])C2=C(C([H])=C(O2)C([H])([H])C([H])([H])N(C([H])([H])C2=C(Cl)C(=C([H])C([H])=C2[H])C(F)(F)F)C([H])([H])C([H])(C2=C([H])C([H])=C([H])C([H])=C2[H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])=C1[H]
[H]N(C1=NC2=C(C([H])=C([H])C([H])=C2C(=O)N([H])C([H])([H])[H])C2=C([H])N=C([H])C([H])=C12)C1=C([H])C([H])=C([H])C([H])=C1Cl
[H]C1=C([H])C(OC2=C([H])C([H])=C([H])C([H])=C2C([H])([H])N2C([H])([H])C([H])([H])C3(C([H])([H])C([H])([H])N(C(=O)C4=C([H])C([H])=C([H])C([H])=[N+]4[O-])C([H])([H])C3([H])[H])C([H])([H])C2([H])[H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]OC(=O)C1=C(C([H])=C([H])C(=C1[H])C([H])([H])N([H])C(=O)C([H])([H])C([H])([H])C([H])([H])OC1=C([H])C([H])=C(C([H])=C1[H])C(=C(\C1=C([H])C([H])=C(O[H])C([H])=C1[H])C([H])([H])C([H])([H])[H])\C([H])([H])C([H])([H])[H])C1=C2C([H])=C([H])C(=O)C([H])=C2OC2=C([H])C(O[H])=C([H])C([H])=C12
[H]OC(=O)[C@@]([H])(OC1=C([H])C([H])=C(Cl)C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C(F)(F)F
[H]N(C(=O)C1=C([H])C(=C([H])C([H])=C1[H])C(F)(F)F)C1=C([H])C([H])=C(C(N([H])C2=NC3=C(C([H])=C([H])C([H])=C3[H])N2C2=NC([H])=NC(Cl)=C2[H])=C1[H])C([H])([H])[H]
[H]ON([H])C(=O)[C@]([H])(C1=C([H])C([H])=C2C([H])=C(OC([H])([H])[H])C([H])=C([H])C2=C1[H])C([H])([H])[H]
[H]OC1([H])C([H])([H])C([H])([H])N(C2=C([H])C([H])=C(N([H])C3=NC4=C(N([H])C(=O)C5=C(C([H])=C([H])C([H])=C5[H])N4C([H])([H])[H])C([H])=N3)C([H])=C2[H])C([H])([H])C1([H])[H]
[H]OC(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(C([H])([H])C1=C([H])C([H])=C([H])S1)C([H])([H])C([H])([H])C([H])([H])N([H])C(=O)[C@@]([H])(N([H])[H])C([H])([H])S[H])C([H])([H])C([H])([H])SC([H])([H])[H]
[H]OC(=O)[C@]([H])(C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C1(C(=O)N([H])C2(C([H])([H])O[H])C([H])([H])C3=C(C([H])=C([H])C([H])=C3[H])C2([H])[H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]\C(=C1/C2=NC3=C([H])C([H])=C([H])C([H])=C3C(=O)N2C([H])([H])C1([H])[H])C1=C([H])C([H])=C(OC([H])([H])C([H])([H])C([H])([H])N2C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])=C1[H]
[H]OC(=O)C([H])([H])N1C(=O)[C@@]([H])(N([H])[C@]([H])(C(=O)O[H])C([H])([H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])S[C@@]([H])(C2=C([H])C([H])=C([H])C([H])=C2[H])C1([H])[H]
[H]OC1=C2C(SC3=C2C([H])=C([H])N(C3=O)C2=C([H])C([H])=C(OC([H])([H])[H])C([H])=C2[H])=NC([H])=C1[H]
[H]N(C(=O)C1=C([H])C([H])=C(Br)C([H])=C1[H])[C@]1([H])C([H])([H])N(C(=O)C([H])([H])[H])[C@]([H])(C(=O)OC([H])([H])[H])C1([H])[H]
[H]N(\N=C(/[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C(=O)C([H])([H])SC1=NN=C(N1N([H])C(=O)C([H])([H])[H])C([H])([H])C1=C(SC2=C1C([H])([H])C([H])([H])C([H])([H])C2([H])[H])N([H])C(=O)C([H])([H])Cl
[H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1C(=O)C([H])([H])S[C@]1([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)C([H])([H])OC(=O)C([H])([H])[H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C2=C([H])C([H])=C(OC3=NC4=C([H])C([H])=C([H])C([H])=C4S3)C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N([H])C(=O)N([H])C1=C(C([H])=C(S1)C#CC1=C([H])C([H])=C([H])C(N([H])C(=O)C2=C([H])C([H])=C([H])C([H])=C2[H])=C1[H])C(=O)N([H])[H]
[H]N(C1=NC(=NC2=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C([H])=C12)N1C([H])([H])C([H])([H])C([H])(N2C([H])([H])C([H])([H])C([H])(F)C([H])([H])C2([H])[H])C([H])([H])C1([H])[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]C1=C([H])C2=C(C(=N1)N1C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])[C@@]3([H])C([H])([H])C([H])([H])[C@]([H])(C([H])([H])C(=O)C([H])([H])S(=O)(=O)C([H])([H])[H])C([H])([H])C3([H])[H])C([H])([H])C1([H])[H])C([H])([H])C([H])([H])O2
[H]ON([H])C(=O)[C@]1(N([H])S(=O)(=O)C2=C([H])C([H])=C(OC3=C([H])C([H])=C(F)C([H])=C3[H])C([H])=C2[H])C([H])([H])OC([H])([H])C1([H])[H]
[H]C1=C([H])C(=C([H])C([H])=C1Cl)N1C(=O)N2C3=C(C([H])=C(N=C13)C([H])([H])[H])N(C([H])([H])C2([H])[H])C([H])(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H]
[H]C1=C2C(=C([H])C(=C1[H])C([H])([H])[H])N(C(=O)C2([H])[H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])[C@@]1(C([H])([H])[H])C([H])([H])C([H])([H])[C@]([H])(OC([H])([H])[H])C([H])([H])C1([H])[H]
[H]O[C@]1([H])C([H])([H])[C@]2([H])C(=O)C([H])=C3C([H])([H])C([H])([H])[C@@]4([H])[C@]5([H])C([H])([H])C([H])([H])C(=O)[C@@]5(C([H])([H])[H])C([H])([H])C([H])([H])[C@]4([H])[C@]13C2([H])[H]
[H]N([H])C(=NC([H])([H])C([H])([H])C([H])([H])[C@]([H])(N([H])C(=O)[C@]([H])(N([H])C(=O)[C@@]1(N([H])C(=O)C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[C@]([H])(C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C(=O)N([H])[C@@]([H])(C(=O)N([H])C([H])([H])C1=C([H])C([H])=C([H])C(=C1[H])C(=O)N([H])[H])C([H])([H])C1=C([H])C2=C([H])C([H])=C([H])C([H])=C2C([H])=C1[H])N([H])[H]
[H]OC(=O)C(=C(/[H])C1=C([H])C(OC([H])([H])C([H])([H])C2=C([H])C([H])=C(C([H])=C2[H])C(F)(F)F)=C([H])C([H])=C1OC([H])([H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C(F)(F)F)\C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]N1C(=O)S[C@]([H])(C1=O)C([H])([H])C1=C([H])C([H])=C(OC([H])([H])C([H])([H])N(C(=O)C([H])([H])C(\[H])=C(/[H])C([H])([H])[H])C([H])([H])[H])C([H])=C1[H]
[H]N(C1=NC2=C([H])C([H])=C(C([H])=C2N1[H])C([H])([H])[H])C1=NC(=C([H])C(=N1)C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)C1=C(C(C(=O)C([H])([H])[H])=C(N1[H])C([H])([H])[H])C([H])([H])[H])C1=C([H])C2=C(OC([H])([H])C([H])([H])O2)C([H])=C1[H]
FC1=CC(F)=C(NC2=CC3=C(C=C2)C(=O)C2=C(CC3)C=CC=C2)C=C1NC(=O)C1=CC=CC=C1
[H]C1=NC(=C([H])N1C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C1=NN(C(=C1C([H])([H])[H])C1=C([H])C([H])=C(Cl)C([H])=C1[H])C1=C([H])C([H])=C(Cl)C([H])=C1Cl
[H]N(C(=O)C(\[H])=C(/[H])C([H])([H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C1=C([H])C(OC([H])([H])[H])=C2N=C([H])C([H])=C(N([H])C3=C([H])C(Br)=C([H])C([H])=C3[H])C2=C1[H]
ON(=O)C1=CC=C(NC(CC(=O)C2=CC=CC=C2)C2=CC(F)=CC=C2)C=C1
[H]N([H])C(=O)C1=C2C(OC([H])([H])[C@]([H])(N(C([H])([H])C([H])([H])C([H])([H])C3=C([H])N([H])C4=C3C([H])=C([H])C([H])=C4OC([H])([H])[H])C3([H])C([H])([H])C([H])([H])C3([H])[H])C2([H])[H])=C(F)C([H])=C1[H]
[H]N(C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1=C([H])N([H])C([H])=N1)S(=O)(=O)C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])OC1=C([H])C2=C(C([H])=C1[H])N(C1=C2C([H])([H])[C@]([H])(N([H])[H])C([H])([H])C1([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=N1
[H]OC(=O)C([H])([H])[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)OC([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H])C(=O)C([H])([H])F
[H]N(C(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C(=O)OC([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C1=C([H])C([H])=C([H])C(Cl)=C1[H]
[H]N(C1=C(C(=NO1)C([H])([H])[H])C([H])([H])[H])S(=O)(=O)C1=C([H])C([H])=C([H])C([H])=C1C1=C([H])C([H])=C(C([H])=C1[H])C1=NN=C([H])O1
[H]N1C(=O)C([H])=C(N=C1C([H])([H])C1=NC2=C(C([H])=C([H])C([H])=C2O1)C1=NC([H])=C([H])C([H])=C1[H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]N(C(=O)[C@]1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C(=O)N1C([H])([H])C([H])([H])N(C2=NC([H])=C(S2)C(C#N)(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H])C1(C#N)C([H])([H])C1([H])[H]
[H]OC1=C([H])C([H])=C(C([H])=C1[H])C1=NN2C(=N1)C1=C(N=C2C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])N([H])C([H])=N1
[H]N(C1=NC([H])=C([H])C2=C1C1=C([H])C([H])=C([H])C([H])=C1N2C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]N(C(=O)C([H])([H])C1=C(Cl)C([H])=C([H])C([H])=C1Cl)C1=NC2=NN(C([H])=C2C2=NC(=NN12)C1=C([H])C([H])=C([H])O1)C([H])([H])[H]
[H]N(C(=S)N1N=C(C(=C1[H])C1=C([H])N2N=C(N=C2C([H])=C1[H])C([H])([H])[H])C1=C([H])C([H])=C([H])C(=N1)C([H])([H])[H])C1=C([H])C(C#N)=C([H])C([H])=C1[H]
[H]N([H])C(=O)C1=C(N([H])C2=C3C([H])=C([H])N([H])C3=NC(=N2)N([H])C2=C(OC([H])([H])[H])C([H])=C3C(=C2[H])N(C(=O)C([H])([H])N(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C3([H])[H])C([H])=C([H])O1
[H]N(C(=O)C1=C([H])N(N=C1[H])C([H])([H])[H])C([H])([H])C1=C([H])N(C2=C([H])C([H])=C([H])C([H])=C2[H])C2=C([H])C(Cl)=C([H])C([H])=C2C1=O
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[H]OC1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[C@]([H])(N([H])[H])C(=O)N([H])[C@@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])C([H])([H])C(=O)N([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])[C@]([H])(O[C@]1([H])O[C@]([H])(C([H])([H])OC(=O)C([H])([H])[H])[C@@]([H])(OC(=O)C([H])([H])[H])[C@@]([H])(OC(=O)C([H])([H])[H])[C@@]1([H])OC(=O)C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H]
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[H]N([C@@]([H])(C([H])([H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])[H])S(=O)(=O)C1=C(Cl)C([H])=C(Cl)C([H])=C1Cl
[H]N(C([H])([H])C1=C([H])C([H])=C(F)C([H])=C1[H])S(=O)(=O)C1=C([H])C2=C(OC([H])([H])C([H])([H])N2C(=O)C([H])([H])[H])C([H])=C1[H]
[H]OC1=C(C([H])=C(C([H])=C1[H])C([H])([H])[C@]1([H])C([H])([H])S(=O)(=O)C([H])([H])[C@]([H])(N([H])C([H])([H])C2=C([H])C(=C([H])C([H])=C2[H])C([H])(C([H])([H])[H])C([H])([H])[H])[C@@]1([H])O[H])C([H])([H])C1=C([H])C([H])=C([H])C(=C1[H])C([H])([H])[H]
CN(C)C(=O)C(CN1C=CC=N1)CN1CCC2(CC1)OCCC1=C2SC=C1
[H]C1=C([H])C([H])=C2C([H])=C(OC([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H])C3=C(SC2=C1[H])C([H])=C([H])C(Cl)=C3[H]
[H]N=C(N([H])[H])C1=C([H])C(OC2=C(F)C(=C(F)C(OC3=C(OC([H])([H])[H])C(=C([H])C([H])=C3[H])C(=O)N(C([H])([H])[H])C([H])([H])[H])=N2)C([H])([H])[H])=C([H])C([H])=C1[H]
[H]C1=C(C#N)N(C(=C1[H])C1=C([H])C([H])=C2C(=O)C([H])([H])C(C2=C1[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)C([H])([H])[H])C1(C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])N(C([H])([H])[C@]2([H])C([H])([H])[C@@]2(C(=O)N(C([H])([H])[H])C([H])([H])C2=C([H])C([H])=C(F)C([H])=C2[H])C2=C([H])C(=C([H])C([H])=C2[H])C([H])([H])[H])C([H])([H])C1([H])[H]
CC(CN(C)C)CN1C(=O)C=C(C2=CC=CC=C2)C2=CC=CC=C12
[H]O[C@@]([H])(C([H])([H])C([O-])=O)C([H])([H])[C@]([H])(O[H])C([H])([H])C([H])([H])C1=C(C(=NN1C1=C([H])C([H])=C(F)C([H])=C1[H])C(=O)N(C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]OC1(C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])[C@@]([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1C([H])([H])[H]
[H]N(C(=O)C1=C(N([H])C(=O)C2=C([H])C([H])=C(C([H])=C2[H])C([H])([H])N(C([H])([H])[H])C([H])([H])C(=O)OC([H])([H])C([H])([H])[H])C([H])=C([H])C(Cl)=C1[H])C1=C([H])C([H])=C(Cl)C([H])=N1
[H]O[C@@]1([H])[C@@]([H])(S[C@]([H])(C(=O)N([H])C([H])([H])C([H])([H])C([H])(C2=C([H])C([H])=C([H])C([H])=C2[H])C2=C([H])C([H])=C([H])C([H])=C2[H])[C@@]1([H])O[H])N1C([H])=NC2=C(N=C(Cl)N=C12)N([H])C([H])([H])C1=C([H])C([H])=C([H])C(I)=C1[H]
[H]N(C(=O)N1C([H])([H])C([H])([H])C([H])([H])[C@]1([H])C(=O)N(C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]N(C(=O)N([H])C1([H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC2=C(C([H])=NN2C2([H])C([H])([H])C([H])([H])N(C(=O)OC([H])([H])[H])C([H])([H])C2([H])[H])C(=N1)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]N(C([H])([H])C([H])([H])C1=C([H])N([H])C2=C1C([H])=C(F)C([H])=C2[H])C([H])([H])[C@]1([H])OC2=C(OC([H])([H])[H])C([H])=C([H])C([H])=C2N([H])C1([H])[H]
[H]N(C(=O)C1=NN(C(=C1C([H])([H])[H])C1=C([H])C([H])=C(Cl)C([H])=C1[H])C1=C([H])C([H])=C(Cl)C([H])=C1Cl)[C@](C1=NOC(=N1)C(F)(F)F)(C([H])([H])[H])C([H])([H])C([H])([H])[H]
[H]C1=C([H])C(OC([H])([H])[H])=C([H])C(=C1[H])N1C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N2C([H])([H])C([H])([H])N(C3=C([H])C([H])=C([H])C(OC([H])([H])[H])=C3[H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]N=C(N([H])[H])C1=C([H])C([H])=C(N([H])C(=O)C([H])([H])C2([H])C([H])([H])C([H])([H])N(C(=O)N([H])C([H])([H])C([H])([H])C([H])(C3=C([H])C([H])=C([H])C([H])=C3[H])C3=C([H])C([H])=C([H])C([H])=C3[H])C([H])([H])C2([H])[H])C([H])=C1[H]
[H]N(C([H])([H])C1=NC(=C([H])N=C1[H])C1=C(OC([H])([H])[H])C([H])=C(F)C([H])=C1[H])C([H])([H])C([H])([H])[H]
[H]N(C(=O)C([H])([H])C1=C(N([H])C2=C([H])C([H])=C([H])C([H])=C12)C1=C([H])C([H])=C([H])C([H])=C1[H])[C@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]O[C@]([H])(C([H])([H])C([H])([H])[H])C([H])([H])[C@]([H])(O[H])[C@@]([H])(N([H])C(=O)C([H])([H])N([H])C(=O)[C@@]([H])(N([H])S(=O)(=O)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]\C(=N/N1C([H])=NN=C1[H])C1=C([H])C(OC([H])([H])[H])=C(OC([H])([H])C2=C([H])C([H])=C(C([H])=C2[H])C([H])([H])[H])C([H])=C1[H]
[H]C1=C(C(=O)C([H])([H])C2=C([H])C(F)=C([H])C([H])=C2[H])C2=C([H])C([H])=C([H])C([H])=C2N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]N(C1=NC([H])=NC(N([H])[C@@]([H])(C([H])([H])[H])[C@]([H])(C2=C([H])C(Br)=C([H])C([H])=C2[H])C([H])([H])C2=C([H])C([H])=C(Cl)C([H])=C2[H])=C1[H])C([H])([H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]OC1=C([H])C(Cl)=C2C3=C1O[C@]1([H])[C@]33C([H])([H])C([H])([H])N(C([H])([H])C4([H])C([H])([H])C4([H])[H])[C@]([H])(C2([H])[H])[C@]32C([H])([H])C([H])([H])[C@@]1(OC([H])([H])[H])[C@]([H])(C2([H])[H])[C@](O[H])(C([H])([H])[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])C([H])=C(OC([H])([H])C([H])([H])C([H])([H])OC2=C(OC([H])([H])[H])C([H])=C([H])C(=C2[H])[C@]2([H])C([H])([H])N(C(=O)OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])[C@@]2([H])C(=O)OC([H])([H])[H])C([H])=C1[H]
[H]C1=C2C3=C(C([H])=C(N=C3N(C3=C([H])C([H])=C(C#N)C([H])=C3C([H])([H])[H])C([H])([H])C2([H])[H])C([H])([H])[H])N1C([H])(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H]
[H]N([H])S(=O)(=O)C1=C([H])C2=C(N([H])C([H])([H])N([H])S2(=O)=O)C([H])=C1SSC1=C([H])C2=C(C([H])=C1S(=O)(=O)N([H])[H])S(=O)(=O)N([H])C([H])([H])N2[H]
[H]N(C1=C2C(=NC3=C(C(=NN13)C([H])([H])C([H])([H])[H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1C([H])([H])[H])C([H])([H])C([H])([H])C2([H])[H])C([H])(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H]
[H]N(C(=O)C([H])=C(C([H])([H])[H])C([H])([H])[H])[C@@]1([H])C([H])([H])C([H])([H])[C@@]2(C([H])([H])[H])[C@@]([H])(C([H])([H])C([H])([H])[C@@]3([H])[C@]4([H])C([H])([H])C([H])=C([C@@]([H])(N(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])[C@@]4(C([H])([H])[H])C([H])([H])C([H])([H])[C@]23[H])[C@@]1([H])OC(=O)C([H])([H])[H]
[H]O[C@@]1([H])[C@@]([H])(O[C@]([H])(C(=O)C([H])([H])C([H])([H])[H])[C@@]1([H])O[H])N1C([H])=NC2=C1N=C(N=C2N([H])[H])C#CC1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C1=C([H])C(F)=C([H])C(=C1[H])C([H])([H])OC1=NC2=C(N1C([H])([H])[H])C(=O)N(C(=O)N2C([H])([H])[H])C([H])([H])[H]
[H]OC(=O)C([H])([H])N(C1=C([H])C([H])=C([H])C([H])=C1[H])S(=O)(=O)C1=C([H])C([H])=C([H])C(=C1[H])[N+]([O-])=O
[H]N(C1=C([H])C([H])=NC2=C1C1=C([H])C([H])=C([H])C(OC([H])([H])[H])=C1N2[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]N(C(=O)C1=NN(C2=C1C([H])=C([H])C(OC([H])([H])[H])=C2[H])C([H])([H])[H])C1([H])C([H])([H])[C@@]2([H])N(C([H])([H])[H])[C@@]([H])(C([H])([H])C([H])([H])C2([H])[H])C1([H])[H]
[H]OC(=O)C1=C([H])C([H])=C(C([H])=C1OC([H])([H])C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[C@]([H])(N([H])C([H])([H])[C@]([H])(O[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H]
[H]OC([H])([H])C([H])([H])ON([H])C(=O)C1=C(N([H])C2=C([H])C([H])=C(I)C([H])=C2F)C(F)=C(F)C(=C1[H])C([H])([H])N(OC([H])([H])[H])C([H])=O
[H]O\N=C1/C(/N([H])C2=C/1C([H])=C([H])C([H])=C2[H])=C1/C(=O)N([H])C2=C1C([H])=C([H])C([H])=C2[H]
[H]C1=C([H])C(=C([H])C([H])=C1Cl)C1=C(C(=NN1C1=C([H])C([H])=C(Cl)C([H])=C1Cl)C1=NC(=O)C(N1C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])[H]
[H]C([H])=[N+]1N=C(C2=C1C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N(C(=O)C1(C2=C([H])C([H])=C([H])C(OC([H])([H])[H])=C2[H])C([H])([H])C([H])([H])N(C2=C(OC([H])([H])[H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H])S(=O)(=O)OC1=C(C([H])=C([H])C([H])=C1C([H])(C([H])([H])[H])C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N1[C@@]2([H])C3=C([H])C([H])=C([H])C([H])=C3[C@@]1(C1=C(C([H])=C([H])C(N=C=S)=C1[H])C2([H])[H])C([H])([H])[H]
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[H]N(C(=O)C([H])([H])C1=C([H])C([H])=C(Cl)C([H])=C1[H])[C@@]([H])(C(=O)N([H])[C@@]1([H])C([H])([H])C([H])([H])N([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]C1=C([H])C([H])=C(O1)C1=C([H])C(=C([H])C([H])=C1[H])[C@]1([H])C([H])([H])[C@]2([H])O[C@@]([H])(C([H])([H])C2([H])[H])[C@@]1([H])C(=O)OC([H])([H])[H]
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[H]N1C2=C([H])C(=C([H])C([H])=C2OC([H])([H])C1=O)C([H])([H])N1C([H])([H])C([H])([H])N(C2=C([H])C([H])=C(C([H])=C2[H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N(C1=C([H])C([H])=C(SC2=NC([H])=C([H])N2C([H])([H])[H])C(Cl)=C1[H])C1=C(C#N)C([H])=NC2=C([H])C(\C([H])=C(/[H])C([H])([H])C([H])([H])N3C([H])([H])C([H])([H])C([H])([H])C([H])([H])C3([H])[H])=C([H])C([H])=C12
[H]N(C(=O)N([H])S(=O)(=O)C1=C(OC2=C([H])C([H])=C(Cl)C([H])=C2[H])C([H])=C([H])C(=C1[H])[N+]([O-])=O)C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
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[H]S\C(=N\C([H])([H])C1=C([H])C2=C(OC([H])([H])O2)C([H])=C1[H])N1C([H])([H])C([H])([H])N(C2=NC([H])=NC3=C([H])C(OC([H])([H])C([H])([H])N4C([H])([H])C([H])([H])C([H])([H])C4([H])[H])=C(OC([H])([H])[H])C([H])=C23)C([H])([H])C1([H])[H]
[H]O\C(OC([H])([H])C([H])([H])[H])=C1\C(=NC(=C(C(=O)OC([H])([H])[H])[C@]1([H])C1=C([H])C([H])=C([H])C(=C1[H])[N+]([O-])=O)C([H])([H])N1C([H])=NC([H])=C1[H])C([H])([H])N1C([H])=NC([H])=C1[H]
[H]N([H])C1=NON=C1C1=NC2=C([H])C(OC([H])([H])[H])=C([H])C([H])=C2N1C1([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(C(=O)C([H])([H])N1C(=O)C2=C(N=C1C1=C([H])C([H])=C([H])C(Cl)=C1[H])C([H])=C([H])C(OC([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])=C2[H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]OC(=O)C1=C(\C([H])=N\N=C(/S[H])N([H])C2([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])=C2C(=C1O[H])C1=C(O[H])C3=C(C(=O)C4=C(C([H])=C(O[H])C(=C4O[H])C([H])([H])[H])C3=O)C(OC([H])([H])[H])=C1C([H])([H])C2([H])[H]
CC1=CC=C(C=N1)C1=NC2=C(C)N=C(N)N=C2N([C@H]2CC[C@@H](CC2)OCCO)C1=O
[H]C1=C([H])C(=C([H])C([H])=C1C([H])([H])[H])[C@@]1([H])C([H])([H])[C@@]2([H])N(C([H])([H])[H])[C@]([H])(C([H])([H])C2([H])[H])[C@@]1([H])C(=O)OC([H])(C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])C([H])=C2C(=O)N(C(=O)C2=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])C1=C([H])C(OC([H])([H])[H])=C([H])C([H])=C1[H]
[H]OC([H])([H])[C@]1([H])N=C(OC1([H])[H])C1=C([H])C([H])=C2C(=C1[H])N(C(=C2C(=O)N([H])C([H])([H])C1=C([H])C([H])=C(F)C(F)=C1[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N([H])C1=C(Cl)C([H])=C(C(=O)OC([H])([H])C([H])([H])N2C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])C(OC([H])([H])[H])=C1[H]
[H]N(C(=O)C([H])([H])[H])C([H])([H])C([H])([H])N(C1=C([H])C(OC([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])OC2=C([H])C([H])=C([H])C(=C2[H])N(C([H])([H])[H])C([H])([H])C([H])([H])N([H])C(=O)C([H])([H])[H])=C([H])C([H])=C1[H])C([H])([H])[H]
[H]N(C1=C([H])C([H])=C(C([H])=C1[H])C1=NC2=C(S1)C([H])=C([H])C([H])=C2[H])C1=NC([H])=NC2=C([H])C(OC([H])([H])[H])=C(OC([H])([H])C([H])([H])C([H])([H])N3C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C3([H])[H])C([H])=C12
[H]C1=C([H])C([H])=C(O1)C1=NN(C(=O)C2=C([H])C([H])=C([H])S2)C(SC([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])=N1
[H]OC(=O)[C@@]([H])(N([H])C(=O)C1=C([H])C2=C([H])C([H])=C([H])C([H])=C2C([H])=C1N([H])C(=O)N([H])C1=C(C([H])=C(C([H])=C1C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]O[C@@]([H])(C1=C([H])C([H])=C(Cl)C(Cl)=C1[H])[C@@]([H])(N1C([H])([H])C([H])=C(C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H])C([H])([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])N1C([H])([H])N(C(=O)C11C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])C([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H]
[H]C1=NC(Cl)=C(N1C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)C([H])([H])[H])C1=C([H])C2=C(O1)C([H])=C([H])C([H])=C2[H]
[H]N1C([H])([H])C2=C([H])C(C#N)=C([H])C([H])=C2C([H])([H])C1([H])[H]
[H]OC(=O)C([H])([H])[C@@]([H])(N([H])C(=O)[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]1([H])N(C(=O)C([H])([H])N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@]([H])(N([H])C(=O)C([H])([H])N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])[H])C([H])([H])C2=C([H])N([H])C3=C([H])C([H])=C([H])C([H])=C23)[C@@]([H])(O[H])C([H])([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C(=O)N([H])[H])C([H])([H])O[H])C([H])([H])[H])C([H])([H])C2=C([H])C([H])=C(O[H])C([H])=C2[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C1=C([H])N=C([H])N1[H])C([H])([H])[H])[C@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])[H])C([H])([H])C(=O)O[H])C([H])([H])C(=O)N([H])[H])C([H])([H])C1=C([H])N=C([H])N1[H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=N[H])N([H])[H])C([H])([H])O[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])O[H])C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])C([H])([H])C(=O)N([H])[C@]([H])(C(=O)N([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])N=C([H])N1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])[H]
[H]N(C(=O)OC([H])([H])C([H])([H])OC([H])([H])[H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)C(=O)N([H])C1([H])C([H])([H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N([H])C1=C([H])C([H])=C([H])C(=C1[H])N1C(=O)O[C@@]([H])(C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C1([H])[H]
[H]OC(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]1([H])N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])N=C(N([H])[H])N([H])[H])C([H])([H])C2=C([H])C([H])=C(O[H])C([H])=C2[H])C([H])([H])C2=C([H])C([H])=C(O[H])C([H])=C2[H])C([H])([H])O[H])C([H])([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])N=C(N([H])[H])N([H])[H])C([H])([H])C2=C([H])N([H])C([H])=N2)C([H])([H])C2=C([H])C([H])=C(O[H])C([H])=C2[H])[C@@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])[H])C([H])([H])C(=O)N([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=O)C([H])([H])C1([H])[H])[C@@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])[H])[C@]([H])(O[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])N=C(N([H])[H])N([H])[H])C([H])([H])C([H])([H])C([H])([H])N=C(N([H])[H])N([H])[H])C([H])([H])C1=C([H])C([H])=C(O[H])C([H])=C1[H]
[H]N(C(=O)C1=C([H])C([H])=C(C([H])=C1[H])N(C([H])([H])C([H])([H])Cl)C([H])([H])C([H])([H])Cl)C1=C([H])C([H])=C([H])C([H])=C1Cl
[H]C1=C([H])C([H])=C(C([H])=C1[H])[C@@]1(C2=C(OC([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])=C([H])C(OC([H])([H])C3=C([H])C([H])=C4C([H])=C([H])C([H])=C([H])C4=N3)=C2[H])C([H])([H])[C@@]2([H])C([H])([H])C([H])([H])[C@]1([H])C2([H])[H]
[H]C([H])=C([H])C([H])([H])SC1=NC2=C(N=N1)C1=C(C([H])=C([H])C([H])=C1[H])N(C(=O)C([H])([H])[H])[C@@]([H])(O2)C1=C(F)C([H])=C([H])C([H])=C1[H]
[H]OC([H])([H])C([H])([H])C([H])([H])C1=C([H])N=C([H])N1C([H])([H])C1=C([H])C([H])=C(Br)C([H])=C1[H]
[H]N(C(=O)C1=NN2C(N([H])C(=O)C3=C([H])C([H])=C([H])C([H])=C23)=C1[H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]N(C1=NC2=C(C([H])=N1)C([H])=C(N1N2C([H])([H])C([H])([H])C1=O)C1=C(Cl)C([H])=C([H])C([H])=C1Cl)C1=C([H])C([H])=C(C([H])=C1[H])C(=O)OC([H])([H])[H]
[H]N(C(=O)C1=C([H])C(F)=C([H])C(C#N)=C1[H])C1=NC(=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]N([H])C1=C(N([H])C(=O)C2=C([H])C([H])=C(N([H])C([H])([H])C(=O)N([H])C3=C(C([H])=C([H])C([H])=C3[H])[N+]([O-])=O)C([H])=C2[H])C([H])=C([H])C([H])=C1[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])N(C1=NS(=O)(=O)C2=C([H])C([H])=C([H])C([H])=C12)C([H])([H])C([H])([H])C([H])([H])OC([H])([H])[H]
[H]OC1=C([H])C([H])=C(C([H])=C1O[H])C([H])([H])C([H])([H])N([H])C(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C(\[H])=C(\[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]N([H])S(=O)(=O)C1=C([H])C([H])=C(C([H])=C1[H])C1=NC2=C(N1[H])N(C(=O)N(C2=O)C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H]
[H]OC(=O)C1=C([H])C(=C([H])C([H])=C1C1=C(C([H])=C(C([H])=C1[H])[C@@]([H])(O[H])C([H])([H])O[H])C(=O)N([H])C1=C([H])C([H])=C(C([H])=C1[H])C(=N[H])N([H])[H])C(=O)N([H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C1=C([H])C([H])=C([H])N2N=C(N=C12)C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H])C1=C(N=C([H])C([H])=C1[H])N(C([H])([H])[H])S(=O)(=O)C([H])([H])[H]
[H]N1C(=O)C([H])([H])C([H])([H])[C@@]2(C([H])([H])[H])[C@@]1([H])C([H])([H])C([H])([H])[C@]1([H])[C@@]3([H])C([H])([H])C([H])([H])[C@]([H])(N(C([H])=O)C([H])([H])[H])[C@@]3(C([H])([H])[H])C([H])([H])C([H])([H])[C@@]21[H]
[H]C1=C(Cl)C(Cl)=C([H])C(=C1[H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H]
[H]N(C(=O)C(\[H])=C(/[H])C1=C([H])C([H])=C([H])C([H])=C1SC1=C(Cl)C([H])=C(Cl)C([H])=C1[H])C([H])([H])[C@@]1([H])OC([H])([H])C([H])([H])C1([H])[H]
[H]C1=NC2=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C([H])=C2C([H])=C1C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C1=C([H])C(Cl)=C(S1)C1=NC(=NO1)C1=C([H])N=C(Cl)C([H])=C1[H]
[H]OC(=O)C([H])([H])C([H])([H])[C@]([H])(N([H])C(=O)C1=C([H])C([H])=C(C([H])=C1F)N(C([H])([H])C#C[H])C([H])([H])C1=C([H])C([H])=C2N=C(N=C(O[H])C2=C1[H])N([H])[H])C(=O)O[H]
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[H]OC1(C2=C([H])C(Cl)=C([H])C([H])=C2[H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])C(C#N)(C2=C([H])C([H])=C([H])C([H])=C2[H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
CN(C(=O)CN1C(=O)N2CCCC3=C2C1=CC(=C3)C1=CC=CC=C1)C1=NC=CC=C1
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CN1C(OCC2=CC3=CC=CC=C3C=C2)=CC2=C1C(=O)N(C)C(=O)N2C
[H]ON(C([H])=O)[C@@]([H])(C([H])([H])C([H])([H])[H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])C1=NC([H])=C([H])S1)C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N([H])C1=NC(=C(Br)C(=N1)N([H])C1=C([H])C([H])=C(Cl)C([H])=C1[H])C([H])([H])[H]
[H]N(C([H])([H])C1=C(N=C(O1)C([H])([H])C([H])([H])C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C(C([H])=C([H])C([H])=C2[H])C([H])([H])[H])C([H])([H])C1([H])[H]
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[H]N(C(=O)N1C([H])([H])C([H])([H])N(C2=NC([H])=C(C([H])=C2Br)C(=O)OC([H])([H])C([H])([H])[H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C1=NC([H])=C2C([H])=C([H])N(C2=N1)C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
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[H]C1=C([H])C(=C([H])C([H])=C1N1C(=O)N2C3=C(C([H])=C(N=C13)C([H])([H])[H])N(C([H])([H])C2([H])[H])C([H])(C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[H])C(F)(F)F
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[H]OP(=O)(O[H])OC1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[C@]1([H])N([H])C(=O)C([H])([H])SC([H])([H])[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@]2(N([H])C1=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C(=O)N([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])C(=O)N([H])[H]
[H]N([H])S(=O)(=O)C1=C([H])C2=C(S1)S(=O)(=O)[C@@]([H])(C([H])([H])[H])C([H])([H])[C@]2([H])N(C(=O)OC([H])([H])C([H])([H])C([H])([H])O[N+]([O-])=O)C([H])([H])C([H])([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])OC1=C([H])C(=C([H])C([H])=C1OC([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]N(C(=O)C1=C([H])C(=C(C([H])=C1[H])N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])[N+]([O-])=O)C1=NC2=C([H])C([H])=C([H])C([H])=C2S1
[H]N(C(=O)C1=NN(C(N2C([H])=C([H])C([H])=C2[H])=C1C([H])([H])[H])C1=C(F)C([H])=C(F)C([H])=C1[H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]N(C(=O)[C@]1([H])[C@]2([H])N(C([H])([H])[H])[C@@]([H])(C([H])([H])C2([H])[H])C([H])([H])[C@]1([H])C1=C([H])C([H])=C(Cl)C([H])=C1[H])C1=C([H])C([H])=NC(Br)=C1[H]
[H]O[C@@]1([H])C([H])([H])C2=C(C([H])=C([H])C([H])=C2N([H])C2=NC([H])=C(O2)C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]C1=C(SC(=C1[H])C1=C([H])C([H])=C([H])C(OC([H])([H])[H])=C1[H])C(=O)N(C([H])([H])[H])C([H])([H])C1=C([H])C(OC([H])([H])[H])=C([H])C([H])=C1[H]
[H]N([H])C1=NC2=C(S1)C([H])([H])[C@@]([H])(N(C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[C@@]1([H])C([H])([H])C([H])([H])[C@]([H])(N([H])C(=O)C(\[H])=C(/[H])C3=C([H])C(OC([H])([H])[H])=C([H])C([H])=C3[H])C([H])([H])C1([H])[H])C([H])([H])C2([H])[H]
[H]N(C(=O)C1=C([H])C(Br)=C([H])C([H])=C1OC([H])([H])[H])C([H])([H])[C@]1([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]O[C@@]1([H])C([H])([H])[C@@]([H])(C(=O)N2C([H])([H])C([H])([H])C([H])([H])[C@]([H])(C2([H])[H])[C@](O[H])(C2=C([H])C(F)=C([H])C([H])=C2C2=C([H])C(=C([H])C([H])=C2[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])OC([H])([H])[H])C([H])([H])[C@@]1([H])N([H])[H]
CN(C1=NC=CC=C1CNC1=C2N=C(NC2=NC=C1C(F)(F)F)C1=CC=C(F)C=C1)S(C)(=O)=O
[H]N([H])C1=NC2=C(S1)C([H])([H])[C@@]([H])(N(C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[C@@]1([H])C([H])([H])C([H])([H])[C@]([H])(N([H])C(=O)C(\[H])=C(/[H])C3=C([H])C(Cl)=C([H])C([H])=C3[H])C([H])([H])C1([H])[H])C([H])([H])C2([H])[H]
[H]N([H])[C@@]([H])(C([H])([H])C(=O)N1C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C([H])([H])N(C1([H])C([H])([H])C1([H])[H])S(=O)(=O)C(F)(F)F)C([H])([H])C1=C(F)C([H])=C(F)C(F)=C1[H]
[H]\C(=C(\[H])C([H])([H])N1C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])OC([H])(C2=C([H])C([H])=C(F)C([H])=C2[H])C2=C([H])C([H])=C(F)C([H])=C2[H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C([H])C([H])=C1OC([H])([H])[H]
[H]OC([H])([H])[C@@]1([H])O[C@@]([H])(C2=C([H])C(=C(Cl)C([H])=C2OC([H])([H])C([H])([H])[H])C([H])([H])C2=NC([H])=C(S2)C2=C([H])C([H])=C([H])C([H])=C2[H])[C@]([H])(O[H])[C@@]([H])(O[H])[C@]1([H])O[H]
[H]C1=C([H])C2=C(C([H])=C1[H])[C@]([H])(C1=C([H])C([H])=C(Cl)C(Cl)=C1[H])C([H])([H])[C@]([H])(C([H])([H])N(C([H])([H])[H])C([H])([H])[H])C2([H])[H]
[H]N([H])C(=NC([H])([H])C([H])([H])C([H])([H])[C@@]([H])(N([H])C(=O)C([H])([H])N1C(=O)C([H])([H])N(C([H])([H])C1([H])[H])S(=O)(=O)C1=C(N=C(S1)N([H])C(=O)C([H])([H])[H])C([H])([H])[H])C(=O)C1=NC([H])=C([H])S1)N([H])[H]
O=C(NCCCCCCC1=CC=CC=C1)OC1=CC=CC(=C1)N1CCNCC1
[H]N([H])C([H])([H])C(=O)N([H])C([H])([H])C(=O)N([H])C([H])([H])C([H])([H])C(=O)N([H])C1=NN=C(S1)S(=O)(=O)N([H])[H]
[H]N=C(N([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[C@@]([H])(N([H])C(=O)C([H])([H])N([H])S(=O)(=O)C1=C([H])C2=C([H])C([H])=C([H])C([H])=C2C([H])=C1[H])C(=O)N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
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[H]N(C(=O)OC1=C([H])C(=C([H])C([H])=C1[H])C([H])([H])N(C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])OC1=C([H])C2=C(C([H])=C1[H])C(=O)C([H])([H])O2)C([H])([H])[H]
[H]N(C(=O)C([H])([H])C([H])([H])N([H])C(=O)C1=C([H])C([H])=C(C([H])=C1[H])[N+]([O-])=O)C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H]
[H]N([H])C1=C2N=C(N=C2N(C([H])=N1)C([H])([H])C1=C([H])C([H])=C(OC([H])([H])[H])C(OC2([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])=C1[H])C(OC([H])([H])C1=C([H])C([H])=C([H])C([H])=C1F)(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C(OC([H])([H])C([H])([H])C(F)(F)F)N=C1[H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)C([H])([H])[H]
[H]SC([H])([H])C(=O)C([H])([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])C([H])([H])[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]OC(=O)[C@@]([H])(N([H])C(=O)[C@@]1([H])N(C([H])([H])C([H])([H])C1([H])[H])S(=O)(=O)C1=C([H])C(Cl)=C([H])C(Cl)=C1[H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1SC([H])([H])[H]
[H]N(C1=C2N=C(OC2=NC([H])=N1)C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC(=O)[C@]([H])(N([H])C(=O)C1=C([H])C([H])=C(C([H])=C1[H])N(C([H])([H])[H])C([H])([H])C1=NC2=C(N=C(N=C2N=C1[H])N([H])[H])N([H])[H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=O)C([H])([H])Cl
[H]N1C(=NC2=C1C(=O)N(C(=O)N2C([H])([H])C1=C([H])C([H])=C([H])O1)C([H])([H])[H])C([H])([H])[H]
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[H]OC(=O)C([H])([H])C([H])([H])N([H])C1=C(C2=C(S1)C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C1=NN=C(S[H])N1N([H])C(=O)C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]N(C(=O)C1=C([H])C([H])=C(C([H])=C1[H])[N+]([O-])=O)C1=C([H])C([H])=C([H])N=C1[H]
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[H][C@]12N(C)CC[C@]1(C)C1=CC(OC(=O)NC)=CC=C1N2C
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[H]N(C1=C2C([H])=NN(C2=NC([H])=N1)C1=C([H])C([H])=C(Cl)C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]O[C@]([H])(C([H])([H])N([H])C([H])([H])C1=C([H])C(=C([H])C([H])=C1[H])N(C([H])([H])[H])C([H])([H])[H])[C@@]([H])(N([H])C(=O)[C@@]1([H])N([H])C(=O)N(C([H])([H])C2=C([H])C([H])=C(C([H])=C2[H])C(F)(F)F)C1([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]O[C@]([H])(C1=C([H])C([H])=C(N([H])S(=O)(=O)C([H])([H])[H])C([H])=C1[H])C([H])([H])N([H])C([H])([H])C([H])([H])OC1=C([H])C([H])=C(C([H])=C1[H])N1C([H])=NC([H])=C1[H]
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[H]C1=C([H])C2=C([H])C(=C([H])C([H])=C2N1S(=O)(=O)C1=C([H])C([H])=C([H])C([H])=C1Br)C([H])([H])N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N1C2=C3C([H])=C(OC4=C(C#N)C([H])=C([H])C(=C4[H])C([H])([H])N4C([H])=NC([H])=C4C([H])([H])N([H])[C@@]([H])(C1=O)C([H])([H])C1=C([H])N=C([H])C([H])=C1[H])C([H])=C([H])C3=C([H])C([H])=C2[H]
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[H]C1=C(ON=C1OC([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
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[H]C1=NOC(=C1C1=C([H])N2C(=NN=C2C([H])(C([H])([H])[H])C([H])([H])[H])C([H])=C1[H])C1=C([H])C(F)=C([H])C([H])=C1F
[H]N1C([H])=C(C2=C1C([H])=C([H])C(OC([H])([H])[H])=C2[H])C([H])([H])C([H])([H])N1C(=O)C([H])([H])C([H])([H])C1([H])[H]
[H]OC1=C(O[H])C(O[H])=C(C([H])=C1[H])C1=C([H])C(=O)C2=C(O[H])C([H])=C([H])C(O[H])=C2C1=O
[H]N([H])C1=NC2=C(C([H])=NN2C([H])([H])C([H])([H])N2C([H])([H])C([H])([H])N(C3=C(F)C(F)=C(F)C([H])=C3[H])C([H])([H])C2([H])[H])C2=NC(=NN12)C1=C([H])C([H])=C([H])O1
[H]OC1=C([H])C([H])=C2N([H])C3=C(C2=C1[H])C1=C(C(=O)N([H])C1=O)C(=C3[H])C1=C(C([H])=C([H])C(=C1[H])C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)N([H])C1=C(Cl)C([H])=C(OC2=C([H])C([H])=NC(=C2[H])C2=NC([H])=C(N2[H])C(F)(F)F)C([H])=C1[H])C1=C([H])C(=C(Cl)C([H])=C1[H])C(F)(F)F
[H]OC(=O)C1=C([H])C([H])=C([H])C([H])=C1C(=O)N([H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1C(SC([H])([H])C2=C([H])C([H])=C(OC([H])([H])[H])C([H])=C2[H])=NN=C1C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
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[H]N(C(=O)C1=NN(C(N2C(=C([H])C([H])=C2C([H])([H])[H])C([H])([H])[H])=C1C([H])([H])[H])C1=C([H])C([H])=C(Cl)C(Cl)=C1[H])C([H])([H])C1=C([H])C(Cl)=C(Cl)C([H])=C1[H]
[H]O[C@]1(C([H])([H])N([H])C(=O)[C@@]2([H])C([H])([H])N([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])[C@@]2([H])C([H])([H])C([H])([H])[C@]1(C([H])([H])S(=O)(=O)N1C([H])([H])C([H])([H])C3(C([H])=C([H])C4=C([H])C([H])=C([H])C([H])=C34)C([H])([H])C1([H])[H])C2(C([H])([H])[H])C([H])([H])[H]
[H]N1C([H])([H])C2=C(Cl)C(Cl)=C([H])C([H])=C2C([H])([H])C([H])([H])C1([H])[H]
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[H][C@@]12CC3=C(CN1CCC1=CC4=C(OCC4)C=C21)C(OC)=C(O)C=C3
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[H]N([H])C(=O)C1=C(SC([H])=C1[H])N([H])C(=O)C([H])([H])C1=C([H])C(F)=C([H])C(F)=C1[H]
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[H]OC(=O)[C@@]([H])(N([H])C(=O)C1=C([H])C2=C([H])C([H])=C([H])C([H])=C2C([H])=C1N([H])C(=O)N([H])C1=C(Cl)C([H])=C(OC(F)(F)F)C([H])=C1Cl)C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
CCOC(=O)C1=CC=C2N=C(C)C3=NN=C(N3C2=C1)C1=CC=CC=C1
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[H]N(C([H])([H])C1=C([H])C([H])=C([H])S1)[C@]([H])(C(=O)N1C([H])([H])C2=C(C([H])=C(OC([H])([H])[H])C(OC([H])([H])[H])=C2[H])C([H])([H])C1([H])[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H][C@]12CN(CC=C)Cc3c(C)ccc(Cc4c(O)c(O)ccc14)c23
[H]OC(=O)C([H])([H])N([H])C(=O)C1=C(O[H])C2=C(C([H])=C([H])C(=C2[H])C([H])([H])N([H])C(=O)[C@@]([H])(N([H])C(=O)C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])[H])N(C1=O)C([H])([H])[H]
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[H]O[C@](C1=C([H])C2=C([H])C(=C(C([H])=C2N1[H])C(F)(F)F)[N+]([O-])=O)(C([H])([H])[H])C([H])([H])OC(=O)C1=C([H])C(Cl)=C([H])C([H])=C1[H]
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[H]N(C(=S)N([H])[C@@]([H])(C([H])([H])OC(=O)C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(C(=C1[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(N([H])S(=O)(=O)C([H])([H])[H])C([H])=C1[H]
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[H]O[C@@]([H])(C([H])([H])N1C([H])=C([H])C(=O)C([H])=C1[H])[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(OC(=O)N1C([H])([H])C([H])([H])C([H])(N([H])[H])C([H])([H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])SC([H])([H])[H])C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(C1=C2C([H])=C([H])C(F)=C([H])C2=C2C(=O)N([H])C([H])=C([H])C2=N1)C1([H])C([H])([H])C(F)(F)C1([H])[H]
[H]N1C2=C([H])C3=C(C4=C(C([H])=C(F)C([H])=C4[H])C3([H])[H])C(F)=C2C(=C([H])C1(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H]
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[H]N(C(=O)C1=C([H])N(C2=C(N([H])C(=O)C([H])=C2[H])C1=O)C([H])([H])C1=C(F)C([H])=C([H])C([H])=C1F)C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]C1=NC(=NC([H])=C1[H])N1C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C(=C([H])C([H])=C2[H])C2=C(OC([H])([H])[H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]\C(Cl)=C(/[H])[C@]1([H])[C@]2([H])N(C([H])([H])[H])[C@@]([H])(C([H])([H])C2([H])[H])C([H])([H])[C@]1([H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]N(C(=O)C(\C#N)=C(/[H])C1=C([H])C(=C(Cl)C([H])=C1[H])[N+]([O-])=O)[C@]([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H]
[H]N([H])C1=NC([H])=C([H])N2C(=NC(=C12)C1=C([H])C([H])=C(OC2=C([H])C([H])=C([H])C([H])=C2[H])C([H])=C1[H])C1=C([H])C([H])=NC([H])=C1[H]
[H]N([H])[C@@]([H])(C([H])([H])[H])C([H])([H])N1C2=C([H])C(SC([H])([H])[H])=C([H])C([H])=C2C([H])([H])C1([H])[H]
[H]N1C(=S)S\C(=C(\[H])C2=C([H])C3=C(N([H])C(=N3)C3=C([H])C([H])=C(O3)C3=C([H])C([H])=C(C([H])=C3[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])=C2[H])C1=O
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[H]C1=C([H])C(C#N)=C(C([H])=C1O[C@@]1([H])C(=O)N(C([H])([H])C1(C([H])([H])[H])C([H])([H])[H])[C@@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])[H])C(F)(F)F
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[H]N1C([H])([H])C([H])([H])N(C2=C(C#N)C3=C(N2C([H])([H])C([H])=C(C([H])([H])[H])C([H])([H])[H])C(=O)N(C([H])=N3)C([H])([H])C2=NC([H])=C([H])C3=C([H])C([H])=C([H])C([H])=C23)C([H])([H])C([H])([H])C1([H])[H]
[H]ON(\C([H])=C(\[H])C(=O)C1=C([H])C([H])=C(F)C([H])=C1[H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H][C@]12CCC[C@]1(C[C@@H](C2)NC1CCOCC1OC)C(=O)N1CCC2=C(C1)C=C(Cl)C=C2
[H]OC(=O)[C@@]([H])(N([H])S(=O)(=O)C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])N([H])C(=O)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1C([H])([H])C([H])([H])N([H])C([H])([H])C1([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1C(=O)C(=O)C2=C([H])C(=C([H])C([H])=C12)[N+]([O-])=O
[H]N(C1=C(Cl)C(=O)C2=C(C([H])=NN=C2[H])C1=O)C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]N([H])C(=O)C1=C([H])C2=C(S1)C([H])=NC([H])=C2SC1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N([H])C1=NC2=C([H])C(=C([H])C([H])=C2C(=N1)N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C([H])O1
[H]N1N=NC(=N1)C1=C(C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])OC1=C([H])C(=NC2=C1C([H])=C([H])C(Cl)=C2[H])C([H])([H])C([H])([H])[H]
[H]C([H])=C([H])C([H])([H])\N=C1/SC([H])=C(N1\N=C(/[H])C1=C([H])C([H])=C([H])C([H])=N1)C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)N([H])C([H])([H])C1(C2=C([H])C(=C([H])C([H])=C2[H])C([H])([H])N2C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C2([H])[H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C1=C(C([H])=C([H])C([H])=C1C([H])(C([H])([H])[H])C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H][C@]12CCCN1[C@@]1([C@@H](CC(=O)N3C\C(=C/C4=CC=CC5=CC=CC=C45)C(=O)\C(C3)=C\C3=C4C=CC=CC4=CC=C3)C2)C(=O)NC2=C1C=CC=C2
[H]OC(=O)C1=C([H])N=C(N([H])C(=O)C2=C([H])C(O[C@@]([H])(C([H])([H])[H])C([H])([H])OC([H])([H])[H])=C([H])C(OC([H])([H])[C@@]([H])(C3=C([H])C([H])=C([H])C([H])=C3[H])C([H])([H])[H])=C2[H])C([H])=C1[H]
[H]N([H])C(=O)C([H])([H])C1=C(Br)N(C2=C([H])C([H])=C(OC([H])([H])C([H])([H])C([H])([H])P([O-])([O-])=O)C([H])=C12)C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N([H])C(=O)C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])[C@]([H])(OC([H])([H])C2=C([H])C(=C([H])C(=C2[H])C(F)(F)F)C(F)(F)F)[C@]1([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C1=NC2=C([H])C([H])=C([H])C([H])=C2C(=N1)N1C([H])([H])C([H])([H])N(C2=C([H])C([H])=C([H])C(Cl)=C2[H])C([H])([H])C1([H])[H]
[H]OC(=O)C([H])([H])[C@]1([H])OC2=C([H])C([H])=C(N([H])C(=O)C3=C([H])C([H])=C(C([H])=C3[H])C(=N[H])N([H])[H])C([H])=C2C([H])([H])C1([H])[H]
[H]OC(=O)C([H])([H])[C@@]1([H])C2=C([H])C([H])=C(OC([H])([H])C3=C([H])C([H])=C([H])C(=C3[H])C3=C(C([H])=C(OC([H])([H])C4=C([H])C([H])=C([H])C5=NC([H])=C([H])N45)C([H])=C3C([H])([H])[H])C([H])([H])[H])C([H])=C2OC1([H])[H]
[H]N(C(=O)N([H])[C@]12C([H])([H])[C@@]3([H])C([H])([H])[C@]([H])(C([H])([H])[C@]([H])(C3([H])[H])C1([H])[H])C2([H])[H])[C@@]1([H])C([H])([H])C([H])([H])[C@]([H])(OC([H])([H])C2=C(F)C([H])=C(OC([H])(C([H])([H])[H])C([H])([H])[H])C([H])=C2F)C([H])([H])C1([H])[H]
[H]C1=C([H])C([H])=C(O1)C1=NN2C([H])=NC3=C(SC(=S)N3C3=C([H])C([H])=C(Cl)C([H])=C3[H])C2=N1
[H]OC(=O)C1=C(O[H])C([H])=C([H])C(=C1[H])S(=O)(=O)N([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@@]([H])(C(=O)N([H])[C@]([H])(C(=O)C1=NC([H])=C(O1)C1=C(Cl)C([H])=C([H])C([H])=C1Cl)C([H])([H])C(=O)O[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)C1=C(C2=C([H])C([H])=C([H])C([H])=C2[H])C2=C([H])C([H])=C([H])C([H])=C2N=C1C([H])([H])N(C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]OC1=C([H])C([H])=C2C(OC(C3=C2C([H])=C([H])C(O[H])=C3C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])=C1C([H])([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@]1([H])C(=O)OC([H])([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]OC([H])([H])C1(C([H])([H])O[C@]2(N(C(=O)C3=C([H])C([H])=C([H])C([H])=C23)C([H])([H])C2=C([H])C([H])=C(C([H])=C2[H])C([H])([H])[H])C2=C([H])C([H])=C(Cl)C([H])=C2[H])C([H])([H])C1([H])[H]
[H]C1=C([H])C(=C([H])C(Cl)=C1Cl)C([H])([H])C(=O)N(C([H])([H])[H])[C@]([H])(C([H])([H])N(C([H])([H])[H])C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)N([H])C1=C([H])C([H])=C(OC2=C([H])C([H])=C(OC([H])([H])C3=C([H])C([H])=C([H])C([H])=C3[H])C([H])=C2[H])C([H])=C1[H])C1=C([H])C(=NN1C([H])([H])[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]O[C@]1([H])C([H])([H])O[C@@]([H])(N2C([H])=C(C3=C(N=C([H])N=C23)N([H])C2=C([H])C([H])=C([H])C(OC([H])([H])C([H])([H])[H])=C2[H])C2=C([H])C([H])=C([H])C([H])=C2[H])[C@]1([H])O[H]
[H]C1=NC([H])=C(N1C([H])([H])[H])[C@]([H])(OC([H])([H])C1=NC([H])=C(C#N)C([H])=C1[H])C1=C([H])C(=C(C#N)C([H])=C1[H])C1=C(C([H])=C([H])C([H])=C1[H])C(F)(F)F
[H]O[C@@]1([H])C([H])([H])C([H])([H])N2C(=O)C(=C(C([H])([H])[H])[C@]12[H])C1=C(C(Cl)=C(C#N)C([H])=C1[H])C([H])([H])[H]
[H]N(C(=O)[C@]([H])(C1=NN(N=N1)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C(OC([H])([H])[H])C([H])=C(OC([H])([H])[H])C([H])=C1OC([H])([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C(Cl)S1)C1=NN(C([H])=N1)C([H])([H])C(=O)N([H])C1=C(F)C([H])=C(C([H])=C1[H])N1C([H])=C([H])C([H])=C([H])C1=O
[H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[C@]1([H])C([H])([H])[C@]2([H])N(C([H])([H])[H])[C@@]([H])(C([H])([H])C2([H])[H])[C@]1([H])C(=O)OC([H])([H])[H]
[H]O[C@@]([H])(C(=O)N1C([H])([H])C([H])([H])C([H])(N2C(=O)N([H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H])C([H])([H])S(=O)(=O)C1=C([H])C2=C([H])C([H])=C(Cl)C([H])=C2C([H])=C1[H]
[H]N1C2=C([H])C([H])=C(C([H])=C2[H])[C@]2([H])C([H])([H])[C@]3([H])N(C([H])([H])[H])[C@@]([H])(C([H])([H])C3([H])[H])[C@]2([H])C([H])([H])OC(=O)C([H])([H])C2=C([H])C([H])=C(C([H])=C2[H])C([H])([H])C1=O
[H]C1=C([H])C([H])=C(C([H])=N1)C1=C([H])C([H])=C(OC([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])=C1[H]
[H]OC(=O)C1=C([H])C([H])=C([H])C([H])=C1OC(=O)C1=C(OC(=C1[H])C([H])([H])[H])C([H])([H])[H]
[H]OC1=C([H])C([H])=C([H])C(=C1[H])C([H])([H])N([H])C1=C2C([H])=C(C([H])=NC2=C([H])C(=C1[H])C(F)(F)F)N1C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]C1=C([H])C([H])=C2C(=O)N(C3=C([H])C([H])=C(O[C@]4([H])C([H])([H])N(C([H])([H])C4([H])[H])C4([H])C([H])([H])C([H])([H])C([H])([H])C4([H])[H])C([H])=C3[H])C(=NC2=C1[H])C([H])([H])[H]
[H]N1[C@@]2([H])C(C(=O)N(C([H])([H])C3=C(Cl)C(Cl)=C([H])C([H])=C3[H])C3([H])C([H])([H])C3([H])[H])=C(C3=C([H])C([H])=C(C([H])=C3[H])C([H])([H])C([H])([H])C([H])([H])OC3=C([H])C([H])=C([H])C([H])=C3[H])C([H])([H])[C@]1([H])C([H])([H])N(C(=O)C([H])([H])[H])C2([H])[H]
[H]O[C@@]1(C2=C([H])C([H])=C(F)C([H])=C2[H])[C@@]([H])(C([H])([H])[H])C([H])([H])N(C(=O)[C@]2([H])C([H])([H])N(C([H])([H])[C@@]2([H])C2=C([H])C([H])=C(F)C([H])=C2F)C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])[C@@]1([H])C([H])([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C(N([H])C2=C([H])C([H])=NC([H])=N2)C([H])=C1[H])C1=NC(=C([H])S1)C1=C([H])C(=C([H])C([H])=C1[H])C(F)(F)F
[H]N([H])C(=O)C1=C([H])C([H])=C(OC2=C([H])C([H])=C(\C([H])=C3/SC(=S)N(C3=O)C3=C([H])C([H])=C(OC([H])([H])C([H])([H])C([H])([H])N4C([H])([H])C([H])([H])C([H])([H])C4([H])[H])C([H])=C3[H])C([H])=C2[H])C([H])=C1[H]
[H]N(C(=O)C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])[C@@]1([H])C([H])([H])N(C(=O)C2([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])[C@]1([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])(N(C(=O)OC([H])([H])[H])C([H])([H])C2([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]C1=C([H])C(=C([H])C([H])=C1F)C([H])(N1C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])[C@]2([H])ON=C(C3=C([H])C([H])=C(OC([H])([H])[H])C(OC([H])([H])[H])=C3[H])C2([H])[H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]N(C(=O)C([H])([H])OC1=C(OC([H])([H])[H])C([H])=C(\C([H])=C(/[H])C2=C([H])C([H])=[N+](C([H])=C2[H])C([H])([H])[H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)C([H])([H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C(OC([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])=C1[H]
[H]N1C2=NC([H])=C([H])C([H])=C2N=C(N2C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C3=C([H])C([H])=C([H])C([H])=C3[H])C([H])([H])C2([H])[H])C2=C1C([H])=C([H])C(=C2[H])C([H])([H])[H]
[H]N(C(=O)N([H])[C@]1([H])C([H])([H])C([H])([H])N(C(=O)C([H])([H])C([H])([H])[H])C([H])([H])[C@@]1([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])[C@@]([H])(C([H])([H])C2=C([H])C([H])=C(F)C([H])=C2[H])C1([H])[H])C1=NC(=C(S1)C(=O)C([H])([H])[H])C([H])([H])[H]
[H]OC1=C(C([H])=C([H])C(OC([H])([H])[H])=C1[H])C(=O)C(\[H])=C(/[H])C1=C([H])C([H])=C(OC([H])([H])[H])C(OC([H])([H])[H])=C1[H]
[H]N1C([H])([H])C([H])([H])N(C2=NSC3=C2C([H])=C(OC([H])([H])[H])C([H])=C3[H])C([H])([H])C1([H])[H]
[H]N(C1=NC(=NC(N2C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])=C1C([H])([H])[H])C1([H])C([H])([H])C1([H])[H])C1([H])C([H])([H])C1([H])[H]
[H]C1=NC2=C(C([H])=C1[H])C([H])=C(C([H])=C2C1=C([H])C([H])=C([H])C(N=[N+]=[N-])=C1[H])C([H])([H])C1=C([H])C([H])=NC([H])=C1[H]
[H]N(N([H])C(=O)C1=C([H])C(=C([H])C([H])=C1[H])[N+]([O-])=O)C(\[H])=C1/C([H])=C([H])C([H])=C([H])C1=O
[H]N(C(=O)C([H])([H])[C@@]([H])(N([H])C(=O)C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1C([H])([H])N(C([H])([H])[H])C([H])([H])[H])C(=O)N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C(Cl)C([H])=N1
[H]N1N=NC(=N1)C1=C(C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1C(=NC(C1=O)(C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC(=O)C([H])([H])C(=O)N([H])C1=C2C(=C(OC3=C([H])C(=C(O[H])C([H])=C3[H])C([H])(C([H])([H])[H])C([H])([H])[H])C(Br)=C1[H])C([H])([H])C([H])([H])C2([H])[H]
[H]C1=C(Br)C([H])=C(Br)C(=C1[H])N1N=NC2=C1N=C(N=C2N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])[H]
[H]OC1=C(Br)C([H])=C(\C([H])=C(/[H])C(=O)C2=C([H])C([H])=C(OC(=O)C3=C([H])C([H])=C(Br)C([H])=C3[H])C([H])=C2[H])C(OC([H])([H])[H])=C1[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C1=C(C(=NC2=C([H])C([H])=C([H])C([H])=C12)C(=O)N(C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(I)C([H])=C1[H])C([H])([H])[H]
[H]C1=C([H])C(OC([H])([H])C([H])([H])F)=C(OC([H])([H])[H])C(=C1[H])C(=O)C1([H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C2=C([H])C([H])=C(C([H])=C2[H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]OC(=O)[C@@]([H])(OC1=NC(=C([H])C(=N1)C([H])([H])[H])C([H])([H])[H])[C@]1(N([H])C([H])([H])C(=O)N(C2=C([H])C([H])=C([H])C([H])=C12)C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC(=O)C([H])([H])[C@@]([H])(N([H])C(=O)C([H])([H])C([H])([H])N([H])C(=O)C1=C([H])C2=C([H])C(=C([H])C([H])=C2O1)C(=N[H])N([H])[H])C1=C(F)C([H])=C([H])C(F)=C1[H]
[H]C([H])=C(C([H])([H])[H])C([H])([H])N1C([H])([H])C([H])([H])C(C#N)(C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]OC1=C2C([H])=C(C3=C([H])N=C([H])O3)C(OC([H])([H])[H])=C([H])C2=NC(=C1[H])C1=C([H])C([H])=C2C(=C1[H])[C@]([H])(N(C(=O)C([H])([H])N1C([H])=NC([H])=C1[H])C([H])([H])[H])C([H])([H])C2([H])[H]
[H]C1=C(N(N=C1C([H])([H])C([H])([H])C(=O)N1C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C(C([H])=C2[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H])C1=NN=C(Cl)C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H]
[H]C1=NN(C2=C1[C@]1(O[C@@]([H])(OC([H])([H])[H])C2([H])[H])C([H])([H])C([H])([H])N(C([H])([H])C2([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N=C(N([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])S(=O)(=O)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H])N1C([H])([H])C([H])([H])N(C2=C(OC([H])([H])[H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]OC1=C2N(N=C(C2=NC(=N1)C1=C([H])C([H])=C([H])C(=C1[H])[N+]([O-])=O)C([H])([H])[H])C([H])([H])[H]
[H]N(N([H])C1=NC(=C(S1)C(=O)C([H])([H])[H])C([H])([H])[H])C(\[H])=C1/C([H])=C([H])C([H])=C([H])C1=O
[H]OC1=C([H])C([H])=C(C([H])=C1N([H])S(=O)(=O)C([H])([H])[H])[C@@]([H])(O[H])C([H])([H])N([H])C([H])([H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])S(=O)(=O)C1=C([H])C([H])=C(N([H])C(=O)N([H])C([H])([H])C2=C(F)C([H])=C([H])C(F)=C2[H])C([H])=C1[H]
[H]OC(=O)C1=C([H])C(N([H])C2=C([H])C(=O)C(=O)C3=C2C([H])=C([H])C([H])=C3[H])=C([H])C([H])=C1[H]
[H]N([C@]1([H])C(=O)N(C2=C([H])C([H])=C(C([H])=C2F)C(=O)C([H])([H])[H])C([H])([H])C1([H])[H])S(=O)(=O)C(\[H])=C(/[H])C1=C([H])C([H])=C(Cl)S1
OC(=O)C1=C(CCCOC2=CC=CC3=CC=CC=C23)C2=CC=C(Cl)C=C2N1
[H]N(C(=O)C(F)(F)F)[C@@]1([H])C2=C([H])C(=C([H])C([H])=C2C([H])([H])C1([H])[H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=NSC3=C([H])C([H])=C([H])C([H])=C23)C([H])([H])C1([H])[H]
[H]OC([H])([H])C([H])([H])[C@]1([H])C([H])([H])N([H])[C@]([H])(C(=O)N2C([H])([H])C([H])([H])C([H])([H])[C@@]2([H])C#N)C1([H])[H]
[H]N(C(=O)C([H])([H])[H])C1=NC([H])=C(\C([H])=C(/[H])C(=O)N([H])C([H])([H])C(=O)N(C2=C(Cl)C(=C(Cl)C([H])=C2[H])C([H])([H])OC2=C([H])C([H])=C([H])N3C(Br)=C(N=C23)C([H])([H])[H])C([H])([H])[H])C([H])=C1[H]
[H]N([H])C1=NC([H])=C(C([H])=N1)C1=NC2=C(SC([H])=C2C([H])([H])[H])C(=N1)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
OC1=CC=CN(CC2=CC=C(C=C2)C2=CC=NC=C2)C1=S
[H]OC1=C([H])C([H])=C2C(C([H])=C([H])C(C3=C([H])C(F)=C([H])C([H])=C3[H])=C2OC2=C([H])C([H])=C(OC([H])([H])C([H])([H])N3C([H])([H])C([H])([H])C([H])([H])C([H])([H])C3([H])[H])C([H])=C2[H])=C1[H]
[H]N(C(=O)C1=C([H])C(OC([H])([H])C([H])=C(C([H])([H])[H])C([H])([H])[H])=C([H])C(OC2=C([H])C([H])=C(C([H])=C2[H])S(=O)(=O)C2([H])C([H])([H])C2([H])[H])=C1[H])C1=NC(=C([H])S1)C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]O[C@]1(C([H])([H])C2=C([H])C([H])=C(OC([H])([H])[H])C([H])=N2)C([H])([H])[C@@]2([H])N([C@@]([H])(C3=C([H])C([H])=C([H])C([H])=C3Cl)C3=C([H])C([H])=C(C([H])=C3Cl)C([H])([H])[H])[C@]([H])(C([H])([H])C2([H])[H])C1([H])[H]
[H]OC1=C(C([H])=C([H])C2=C1[C@]13C([H])([H])C([H])([H])N(C([H])([H])C4([H])C([H])([H])C([H])([H])C4([H])[H])[C@]([H])(C2([H])[H])[C@]1(O[H])C([H])([H])C([H])([H])[C@@]([H])(O[H])C3([H])[H])C(=O)N([H])[H]
[H]C1=NN2C(SC(=C2C2=C([H])C([H])=C(F)C([H])=C2[H])C2=C([H])C([H])=C(C([H])=C2[H])S(=O)(=O)C([H])([H])[H])=N1
[H]N([H])C(=NC([H])([H])C([H])([H])C([H])([H])[C@@]([H])(N([H])C(=O)[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)C([H])([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])=O)N([H])[H]
[H]N(C(=O)C([H])([H])[C@@]1([H])N(C2=C(N([H])C1=O)C([H])=C([H])C([H])=C2[H])S(=O)(=O)C1=C([H])C(Cl)=C(Cl)C([H])=C1[H])[C@@]1([H])C2=C(C([H])=C(C([H])=C2[H])C([H])([H])N2C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(C(=O)C1=C(N2N=C([H])C(=C2N=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])OC1=C([H])C([H])=C(F)C([H])=C1[H]
[H]N([H])C1=C([H])C2=C(N=C3C4=C([H])C([H])=C([H])C([H])=C4C([H])([H])C3=C2N([H])[H])C([H])=C1[H]
[H]N1C(=O)C2=C(N=C1C([H])([H])[H])N(N=C2SC([H])([H])[H])C1=C(Cl)C([H])=C(Cl)C([H])=C1Cl
[H]N1C(OC([H])([H])C#CC([H])([H])C([H])([H])[H])=NC2=C(C1=O)C(=C([H])C(=O)O2)C([H])([H])C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N=C(N([H])[H])N([H])S(=O)(=O)C1=C([H])C([H])=C(N([H])C(\[H])=C2/C(=O)N([H])C3=C([H])C([H])=C([H])C([H])=C23)C([H])=C1[H]
[H]N(C(=O)C1=C(N([H])C(=O)C2=C([H])C([H])=C(C([H])=C2[H])C2=C([H])C(=C([H])C([H])=C2[H])N2C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])=C([H])C(Cl)=C1[H])C1=C([H])C([H])=C(Cl)C([H])=N1
[H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])OC1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C(=O)N(C([H])([H])[H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])(C2=C([H])C([H])=C([H])C([H])=C2[H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C(Cl)C([H])=C1[H])C([H])([H])C1=C(N(C2=C([H])C([H])=C([H])C([H])=C2[H])C2=C([H])C(OC([H])([H])[H])=C([H])C([H])=C2C1=O)C(=O)OC([H])([H])[H]
[H]ON([H])C(=O)[C@@]([H])(C([H])([H])O[H])[C@]([H])(C(=O)N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C(=O)N([H])C([H])([H])[H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]ON([H])C(=O)C1(C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])C1([H])C([H])([H])C1([H])[H])S(=O)(=O)C1=C([H])C([H])=C(C([H])=C1[H])N1C([H])([H])C([H])([H])C([H])(C(=O)N2C([H])([H])C([H])([H])N(C3=C(C(=C([H])C([H])=C3[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]C1=C([H])C2=NC3=C([H])C([H])=C([H])C([H])=C3C(O[C@]([H])(C(=O)OC([H])([H])[H])C3=C([H])C([H])=C4OC([H])([H])OC4=C3[H])=C2C([H])=C1[H]
[H]N(C(=O)C1=C(C2=C([H])C([H])=C(C([H])=C2[H])C(F)(F)F)C(=C([H])C([H])=C1[H])C([H])([H])[H])C1=C([H])C2=C(C([H])=C1[H])C([H])([H])[C@]([H])(N1C([H])([H])C([H])([H])N(C(=O)OC([H])([H])[H])C([H])([H])C1([H])[H])C2([H])[H]
[H]N([H])C(=O)C1=C(SC([H])=C1[H])N([H])C(=O)C([H])([H])SC1=NC2=C(C(=C(S2)C([H])([H])[H])C([H])([H])[H])C(=O)N1C([H])([H])C([H])=C([H])[H]
[H]C1=C(N(N=C1C([H])([H])OC1=C([H])C(=C([H])C(F)=C1[H])C1(OC([H])([H])[H])C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C1=C([H])C(=C(OC2=C([H])N=C(C([H])=C2[H])C([H])([H])[H])C([H])=C1[H])C([H])([H])[H])C1=NC([H])=NC2=C([H])C([H])=C([H])C(O[C@@]([H])(C(=O)N(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])=C12
[H]N([H])C(=O)\N=[N+]1\C([H])=C(C([H])=C([H])C1([H])[H])[C@@]1([H])SC([H])([H])C2=C(C([H])=C([H])N12)C(=O)C1=C([H])N(C(=O)N(C([H])([H])[H])C([H])([H])[H])C2=C1C([H])=C([H])C(=C2[H])C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]N(C(=O)C1([H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H])[C@]([H])(C1=NC([H])=C(N1[H])C1=NC2=C([H])C([H])=C([H])C([H])=C2C(OC([H])([H])[H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C(=O)C([H])([H])[H]
[H]OC1=NC([H])=NC(=C1[H])N1C(=O)N(C(=O)C11C([H])([H])C([H])([H])N(C([H])([H])C2=C(C([H])=C([H])C([H])=N2)C([H])([H])[H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=NO1
[H]OC1=NC([H])=C(Br)C([H])=C1C(=O)N([H])C1=C2N=C([H])C([H])=C([H])C2=C([H])C([H])=C1[H]
[H]C1=NC(OC([H])([H])[H])=C([H])C([H])=C1N1C(=NN=C1C([H])([H])OC([H])([H])[H])N1C([H])([H])C([H])(OC2=C(C([H])=C(F)C([H])=C2[H])C([H])([H])[H])C1([H])[H]
[H]N(OC([H])([H])[H])C(=O)C1=C(F)C([H])=C(F)C(N([H])C2=NC([H])=NN3C([H])=C(C4=NN=C(O4)C([H])([H])C4([H])C([H])([H])C4([H])[H])C(=C23)C([H])(C([H])([H])[H])C([H])([H])[H])=C1[H]
[H]N(C(=O)C1=C(OC([H])([H])[H])C([H])=C([H])C(=C1[H])C([H])([H])[C@@]1([H])SC(=O)N([H])C1=O)C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C(F)(F)F
[H]C1=C([H])C(=C(O1)C([H])([H])N(C(=O)O[C@@]1([H])C([H])([H])[C@]2([H])C([H])([H])C([H])([H])[C@]([H])(C1([H])[H])[N+]2(C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H]
[H]N(C(=O)N([H])[C@@]1([H])C(=O)N(C([H])([H])C(=O)N([H])C2=C([H])C([H])=C(C([H])=C2[H])C([H])([H])[H])[C@@]([H])(C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])[C@@]([H])(C2=C(C([H])=C([H])C([H])=C2[H])C([H])([H])[H])C1([H])[H])C1=C([H])C([H])=C([H])C(=C1[H])C([H])([H])[H]
[H]OC(=O)C([H])([H])[C@@]1(O[H])C2=C(O[C@]([H])(C([H])([H])[H])C1([H])[H])C([H])=C(C(=C2[H])[N+]([O-])=O)C([H])([H])[H]
[H]C1=C(Cl)C([H])=C2C(=C1[H])N1C(=C(C(=O)C([H])([H])C1([H])[H])C([H])([H])[H])[C@@]([H])(C([H])([H])[H])C2([H])[H]
[H]C1=C(C(=O)C2([H])C(C([H])([H])[H])(C([H])([H])[H])C2(C([H])([H])[H])C([H])([H])[H])C2=C(C([H])=C(C([H])=C2[H])C(F)(F)F)N1C([H])([H])C1([H])C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]OC(=O)[C@]([H])(N([H])C(=O)C1=C([H])C([H])=C([H])C([H])=C1N([H])C(=O)C(\[H])=C(/[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)C([H])([H])N1C(Cl)=C([H])N=C(N([H])C([H])([H])C(F)(F)C2=C([H])C([H])=C([H])C([H])=N2)C1=O)C([H])([H])C1=C(OC([H])([H])[H])C([H])=C([H])C([H])=N1
[H]OC(=O)C(\[H])=C(/[H])C(=O)N([H])[C@]([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])N([H])C(=O)[C@@](N([H])C(=O)O[C@]1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@]1([H])C([H])([H])[H])(C([H])([H])[H])C([H])([H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H]
[H]N(C(=O)C([H])([H])[H])C1=NC(=C(N1[H])C1=C([H])C2=NC([H])=C([H])N=C2C([H])=C1[H])C1=NC(=C(F)C([H])=C1[H])C([H])([H])[H]
[H]N(C(=O)N([H])C([H])([H])C([H])([H])OC([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])[N+]([O-])=O
[H]N([H])S(=O)(=O)OC1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N(N1C([H])=NN=C1[H])C1=C([H])C([H])=C(C#N)C(=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)C1=C([H])C([H])=C(\C([H])=C(/[H])C(=O)N([H])C([H])([H])C(=O)N(C2=C(Cl)C(=C(Cl)C([H])=C2[H])C([H])([H])OC2=C([H])C([H])=C([H])C3=C2N=C(N3C([H])([H])C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C([H])=C1[H])C([H])([H])[H]
[H]OC(=O)C([H])([H])C([H])([H])C1=C([H])C(=NO1)[C@@]([H])(N([H])C(=O)C([H])([H])C1=C([H])C([H])=C(N([H])C(=O)N([H])C2=C(C([H])=C([H])C([H])=C2[H])C([H])([H])[H])C([H])=C1[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C1=C([H])C(Br)=C(SC2=NC([H])=C([H])N2C([H])([H])[H])C([H])=C1[H])C1=C(C#N)C([H])=NC2=C1C([H])=C(OC([H])([H])[H])C(OC([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])=C2[H]
[H]N1N=NC(=N1)C1=C(C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1C(=O)N(N=C1C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]OC1=C(SC(=N1)C1=C([H])C([H])=C(Br)C([H])=C1[H])C([H])([H])[H]
[H]N=C(N([H])[H])N([H])C(=O)C1=NC(C2=C([H])OC([H])=C2[H])=C(N=C1N([H])[H])N([H])C([H])([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N([H])C(=O)C1=C(N([H])C2=C(F)C([H])=C(F)C([H])=C2[H])C2=C([H])C(N3C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C3([H])[H])=C(OC([H])([H])[H])C([H])=C2N=C1[H]
[H]N(C1([H])C([H])(OC([H])([H])[H])OC([H])(C([H])([H])OS([O-])(=O)=O)C([H])(OC2([H])OC([H])(C([O-])=O)C([H])(OC3([H])OC([H])(C([H])([H])OS([O-])(=O)=O)C([H])(OC4([H])OC([H])(C([O-])=O)C([H])(OC5([H])OC([H])(C([H])([H])OS([O-])(=O)=O)C([H])(OC([H])([H])[H])C([H])(OC([H])([H])[H])C5([H])N([H])S([O-])(=O)=O)C([H])(OC([H])([H])[H])C4([H])OC([H])([H])[H])C([H])(OS([O-])(=O)=O)C3([H])OS([O-])(=O)=O)C([H])(OC([H])([H])[H])C2([H])OS([O-])(=O)=O)C1([H])OC([H])([H])[H])S([O-])(=O)=O
[H]C1=NC(N2C([H])([H])C([H])([H])N(C([H])([H])C3=C([H])C([H])=C([H])C([H])=C3[H])C([H])([H])C2([H])[H])=C2N=C(OC2=N1)C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C1=C([H])C(=C([H])C([H])=C1Cl)N1C(=C(C2=C1C([H])([H])C([H])([H])N(C2=O)C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])[H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]N1C(=N[C@]([H])(C2=C([H])C([H])=C(Cl)C([H])=C2[H])[C@@]1([H])C1=C([H])C([H])=C(Cl)C([H])=C1[H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1OC([H])(C([H])([H])[H])C([H])([H])[H]
[H]O[C@@]1([H])C([H])([H])C([H])([H])C([H])([H])[C@@]([H])(N([H])C(=O)C2=NOC(=C2Cl)C2=C([H])C([H])=C(F)C([H])=C2[H])C1([H])[H]
[H]C1=C([H])C(=C([H])C(OC([H])([H])[H])=C1[H])C(=O)N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@]1([H])C([H])([H])C([H])([H])OC1=C([H])C([H])=C(Cl)C(Cl)=C1[H]
[H]C1=C([H])C([H])=C(C(=N1)N1C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])S(=O)(=O)C1=C([H])C([H])=C(C([H])=C1[H])C(F)(F)F)C(F)(F)F
[H]N(C(=O)C(\[H])=C(/[H])C1=C([H])C([H])=C([H])C([H])=C1C([H])([H])C1=C([H])C2=C([H])C([H])=C(OC([H])([H])C3=C([H])C([H])=C([H])C([H])=C3[H])C([H])=C2C([H])=C1[H])S(=O)(=O)C1=C([H])C(Br)=C([H])C([H])=C1OC([H])([H])[H]
[H]OC(=O)[C@@]([H])(N([H])C(=O)C1=C([H])C2=C(N(C1=O)C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N([H])S(=O)(=O)OC([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]O[C@]1([H])[C@]([H])(O[H])[C@@]2(C(=O)N([H])C([H])([H])[H])C([H])([H])[C@]2([H])[C@@]1([H])N1C([H])=NC2=C1N=C(N=C2N([H])C([H])([H])C1=C([H])C(Cl)=C([H])C([H])=C1[H])C#CC([H])([H])C([H])([H])C(=O)N([H])C([H])([H])C([H])([H])N([H])[H]
[H]ON([H])C(=O)C([H])([H])[C@]([H])(C1=NC(=NO1)C([H])([H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C([H])([H])C([H])([H])C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]OC([H])([H])C(=O)N(OC([H])([H])[H])C([H])([H])C1=C([H])C(C(=O)N([H])OC([H])([H])C([H])([H])O[H])=C(N([H])C2=C([H])C([H])=C(I)C([H])=C2F)C(F)=C1F
[H]N([H])C1=NC(N([H])[H])=C(C#C[C@@]([H])(C2=C([H])C(OC([H])([H])[H])=C([H])C(=C2[H])C2=C([H])C(=C([H])C(=C2[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C(=N1)C([H])([H])[H]
[H]N([H])C(=O)C1=C([H])C([H])=C([H])C([H])=C1N([H])C1=C([H])C([H])=C([H])C(OC([H])([H])C([H])([H])C2=C([H])C([H])=C([H])C(=C2[H])C([H])([H])[H])=C1[H]
[H]N(C(=O)C([H])([H])N1C([H])([H])C([H])([H])N(C2=C3N=C(N([H])C3=NC([H])=C2[H])C2=C([H])C([H])=C(C([H])=C2[H])N(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H])C1=NC([H])=C([H])S1
COC(=O)[C@@]12CC3CC(C1)[C@H](OC(=O)N1CC[C@H](C1)NC(=O)OC(C)(C)C)C(C3)C2
[H]O[C@@]1([H])OC([H])([H])C([H])([H])[C@]1([H])N([H])C(=O)[C@@]([H])(N([H])C(=S)N([H])C1=C([H])C([H])=C(C#N)C([H])=C1[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N=C(N([H])C1=C([H])C([H])=C2N([H])C([H])=C(C2=C1[H])[C@]1([H])C([H])([H])C([H])([H])[C@]([H])(N([H])C([H])([H])C([H])([H])[H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C([H])S1
[H]N([C@@]1([H])C([H])([H])N(C#N)C([H])([H])C1([H])[H])S(=O)(=O)C1=C([H])C(Br)=C([H])C([H])=C1[H]
[H]OC(=O)C([H])([H])[C@@]1([H])C2=C(C3=C([H])C(=C([H])C(=C3N2C([H])([H])C2=C([H])C([H])=C(Cl)C([H])=C2[H])C2([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])S(=O)(=O)C([H])([H])[H])C([H])([H])C1([H])[H]
FCCNC(=O)C1=CC2=C(CCC3=C(C=CC(NC4=C(F)C=C(F)C=C4)=C3)C2=O)C=C1
[H]N([H])C1=NC(N([H])[H])=C2C([H])=C(C([H])=C([H])C2=N1)N(C([H])([H])C1=C(OC([H])([H])[H])C([H])=C([H])C(OC([H])([H])[H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]OC1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[C@]([H])(N([H])[H])C(=O)N([H])[C@]1([H])C(=O)N([H])[C@]([H])(C(=O)N([H])C([H])([H])C(=O)N([H])[C@]([H])(C(=O)N([H])[C@@]([H])(C(=O)N([H])[C@@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[H])C([H])([H])C([H])([H])C([H])([H])N=C(N([H])[H])N([H])[H])C([H])([H])SSC1(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])O[H])C([H])([H])C1=C([H])C([H])=C(O[H])C([H])=C1[H]
[H]N(C(=O)C1=C([H])C([H])=C(O1)C#N)C1=C(C([H])=C(C([H])=C1[H])N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H])C1=C([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]N(C1=C([H])C([H])=C2N([H])C([H])=C(C2=C1[H])C([H])([H])[C@]1([H])N([H])C([H])([H])C([H])([H])C1([H])[H])S(=O)(=O)C1=C([H])C([H])=C([H])C([H])=C1I
[H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])OC1=C([H])C2=C(C([H])=C1[H])N1C(=C(C(=O)C([H])([H])C1([H])[H])C([H])([H])[H])C([H])([H])C2([H])[H]
[H]OC1=C([H])C([H])=C(N([H])C2=NC(=NC([H])=C2C2=NN=C(O2)C2([H])C([H])([H])C2([H])[H])N([H])C([H])([H])C([H])([H])C2=C([H])C([H])=NC([H])=C2[H])C([H])=C1[H]
[H]O[C@@]([H])(C1=C(OC([H])([H])[H])C(OC([H])([H])[H])=C([H])C([H])=C1[H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C2=C([H])C([H])=C(F)C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N(C(=O)[C@]([H])(N(C(=O)C1=C([H])C([H])=C(N1[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H])C([H])([H])[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]OC1=C([H])C([H])=C(C([H])=C1[H])C1=C(SC([H])([H])[H])C2=C([H])C(O[H])=C([H])C([H])=C2C1=O
[H]N(C(=O)OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])[C@]([H])(C(=O)OC([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H]
[H]N(C(=O)C1=C([H])N=C(N2C([H])([H])C([H])([H])N(C([H])([H])C2([H])[H])C2([H])C([H])([H])C([H])([H])N(C([H])([H])C3=C([H])C([H])=C(Cl)C([H])=C3[H])C([H])([H])C2([H])[H])C(Cl)=C1[H])C([H])([H])C1=C([H])C(Cl)=C(Cl)C([H])=C1[H]
Nc1nccc(n1)-c1c[nH]c(c1)C(=O)N[C@H](CO)c1ccccc1
[H]\C(=C(\[H])[N+]([O-])=O)C1=C([H])C([H])=C(OC(=O)C2=C([H])C([H])=C([H])C([H])=C2[H])C(OC([H])([H])[H])=C1[H]
[H]N([H])[C@@]1([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C(C([H])=C2[H])C2=C([H])N(N=C2[H])C([H])([H])[H])C([H])([H])[C@@]1([H])C(=O)N1C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C#N
[H]N(C([H])([H])C1=NC([H])=C([H])C([H])=C1[H])C([H])([H])[C@@]1([H])C([H])([H])N(C([H])([H])C([H])([H])C2=C([H])N([H])C3=C([H])C([H])=C(C([H])=C23)N2C([H])=NN=C2[H])C([H])([H])C1([H])[H]
[H]OC1=C(C(=NN1C([H])([H])C1=C([H])C(OC([H])([H])[H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C2OC([H])([H])OC2=C1[H]
[H]N1C(=O)N(C(=O)C1(C1=C([H])C([H])=C(Br)C([H])=C1[H])C1=C([H])C([H])=C(Br)C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]N([H])C(=O)C1=C([H])C([H])=C([H])C([H])=C1N1C([H])([H])C([H])([H])N(C([H])([H])[C@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])N2C(=NC(=C(C(=O)OC([H])([H])[H])[C@]2([H])C2=C([H])C(F)=C(F)C([H])=C2[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N(C(=O)OC([H])([H])[C@@]([H])(OC([H])([H])[H])C([H])([H])OC(=O)N(C(=O)C([H])([H])[H])C([H])([H])C1=[N+](C([H])=C([H])C([H])=C1[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]OC(=O)C([H])([H])C([H])([H])[C@]([H])(N([H])C(=O)C1=C([H])C(=C([H])C(=N1)C1=C([H])C([H])=C([H])C([H])=C1[H])N1C([H])([H])C([H])(C(=O)N([H])[H])C1([H])[H])C(=O)N1C([H])([H])C([H])([H])N(C(=O)OC([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]O[C@@]1([H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[C@]11C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])[C@@]2(OC([H])([H])C([H])([H])N(C(=O)C3=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C(OC([H])([H])[H])=C3[H])C2([H])[H])C2=C([H])C(Cl)=C(Cl)C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N([H])C1=NN([H])C2=C([H])C(=C([H])C([H])=C12)C1=C([H])C([H])=NC(=N1)N([H])[H]
[H]N1N=C(C([H])=C1C(=O)N1C([H])([H])C([H])([H])N(C2=C(OC([H])([H])C3=C([H])C(F)=C([H])C([H])=C3[H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]N1C([H])([H])C([H])([H])N(C2=C([H])C3=C(N([H])C(=O)C4=C(C([H])=C(O4)C4=C([H])C([H])=C(Cl)C([H])=C4[H])C3([H])[H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N([H])C1=N[C@@](C(=O)C([H])([H])S1)(C1=C([H])C(=C([H])C([H])=C1F)C([H])([H])C(=O)C1=NC([H])=C(OC([H])([H])[H])N=C1[H])C([H])([H])[H]
[H]N(C(=O)C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C(OC([H])([H])[H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H])C([H])([H])C1=NC2=C([H])C(F)=C([H])C([H])=C2C(=O)N1C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC(=O)C([H])([H])[C@@]([H])(C#CC([H])([H])[H])C1=C([H])C([H])=C(OC2=C(OC([H])(F)F)C([H])=C(C([H])=C2[H])C(F)(F)F)C([H])=C1[H]
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[H]N(C(=O)C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])OC1=C([H])C([H])=C(C([H])=C1[H])C(=O)N1C([H])([H])C([H])([H])C([H])(N2C(=O)N([H])C([H])([H])C3=C2C([H])=C([H])C([H])=C3[H])C([H])([H])C1([H])[H]
[H]C1=C(C([H])=C(C2=C1C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])S2)C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C(=O)C([H])([H])C([H])([H])C([H])([H])[H]
[H]OC1=C([H])C(=C(C(=C1[H])C([H])([H])[H])C([H])([H])[C@]([H])(N([H])[H])C(=O)N1C([H])([H])C2=C(C([H])=C([H])C([H])=C2[H])C([H])([H])[C@@]1([H])C([H])([H])N([H])C(=O)N([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H]
[H]OC([H])([H])C1=NN(C2=C1C(=O)N([H])C(=N2)C([H])([H])[H])C1=C(Cl)C([H])=C(Cl)C([H])=C1Cl
[H]N(C(=O)C([H])([H])OC(=O)C1=NN([H])C2=C([H])C([H])=C([H])C([H])=C12)C1=C([H])C(=C([H])C([H])=C1[H])S(=O)(=O)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1OC([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])S(=O)(=O)C1=C([H])C([H])=C(N([H])[C@@]([H])(C([H])([H])SC2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])N2C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])C(=C1[H])[N+]([O-])=O
[H]OC(=O)C([H])([H])C1([H])C([H])([H])C([H])([H])N(C(=O)C([H])([H])N2C(=O)[C@@]([H])(C3=C(C([H])=C(Cl)C([H])=C3[H])[C@@]([H])(C3=C(Cl)C([H])=C([H])C([H])=C3[H])C2([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N(C(=O)C1=C([H])N=C([H])N(C1=O)C([H])([H])C1=C([H])C([H])=C(F)C(F)=C1[H])C([H])([H])C#CC1=C([H])C2=C(N=C([H])N=C2C([H])=C1[H])N(C([H])([H])[H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C1=C([H])N=C([H])C(=C1[H])C1=C([H])N=C2N([H])C([H])=C(C2=C1[H])C1=C([H])C(C#N)=C([H])C([H])=C1[H])S(=O)(=O)C1=C([H])C([H])=C(F)C([H])=C1F
[H]OC(=O)C([H])([H])C([H])([H])[C@]([H])(N([H])[H])C(=O)N1C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N1C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)O[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(O[H])C([H])=C1[H])[C@@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])[H])[C@@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C(=O)O[H])C([H])([H])C([H])([H])C(=O)O[H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C(F)(F)P(=O)(O[H])O[H])C([H])([H])C([H])([H])C(=O)N([H])[H]
[H]N([H])N([H])C(=O)N([H])[H]
[H]N(\C(=N/C#N)N([H])[C@]([H])(N([H])C(=O)C([H])([H])C1=C([H])C(F)=C(C([H])=C1[H])C([H])([H])[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C([H])N=C1C([H])([H])[H]
CC1=C(C=CC=C1Cl)C(=O)N1CCC[C@@H](C1)C1=NN=C(O1)C1=CC=CC=C1
[H]C1=C2C(=O)OC3=C(C(=O)C([H])([H])C([H])([H])C3([H])[H])C2=C([H])C(OC([H])([H])[H])=C1OC([H])([H])[H]
[H]N([H])S(=O)(=O)C1=C([H])C([H])=C(C([H])=C1[H])N1N=C(C([H])=C1C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])C(F)(F)F
[H]OC(=O)C([H])([H])N1N=C(N(C1=O)C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C(C([H])=C([H])C([H])=C1[H])C1=NN([H])N=N1)C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]OC1=C(O[H])C([H])=C(C([H])=C1[H])C(=O)C([H])([H])SC1=NN([H])C(=N1)C1=C([H])C([H])=NC([H])=C1[H]
[H]O[C@]([H])(C([H])([H])[H])[C@]1([H])N([H])C(=O)[C@]([H])(N([H])C(=O)[C@]([H])(N([H])C(=O)[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)C([H])([H])N(C(=O)[C@]([H])(N([H])[H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])SSC([H])([H])C([H])([H])N(C(=O)[C@]([H])(N([H])C1=O)C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C(=O)N([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H])C([H])([H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])[H]
[H]C1=C([H])C([H])=C(C(=C1[H])C([H])([H])[H])C([H])([H])C(=O)N1C([H])([H])C([H])([H])C([H])(N2C([H])([H])C([H])([H])C([H])(C([H])([H])C3=C([H])C(Cl)=C([H])C([H])=C3Cl)C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]N(C(=O)OC([H])([H])C#CC([H])([H])OC1=NC(=NC(N([H])S(=O)(=O)C2=NC([H])=C(C([H])=C2[H])C([H])([H])[H])=C1OC1=C([H])C([H])=C([H])C([H])=C1OC([H])([H])[H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N([H])C1=NC(N([H])[H])=C2C(N=C([H])C(=C2C([H])([H])[H])C([H])([H])SC2=C([H])C(OC([H])([H])[H])=C([H])C([H])=C2[H])=N1
[H]N(C(=O)C([H])([H])N(C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C([H])C2=C1C(=O)C1=C(N([H])N=C21)C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]OC(=O)[C@]([H])(N([H])C(=O)C([H])([H])[C@@]([H])(S[H])C(F)(F)C(F)(F)F)C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)C([H])([H])C([H])([H])N([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])C1=C2C(=NC3=C([H])C([H])=C([H])C([H])=C13)C([H])([H])C([H])([H])C2([H])[H])C1=C([H])C([H])=C2C3=C4C(C([H])=C([H])C([H])=C4C(=O)C2=C1[H])=C([H])C([H])=N3
[H]OC(=O)C([H])([H])C([H])([H])[C@@]1([H])N([H])C(=O)[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)C([H])([H])[H])C([H])([H])C([H])([H])[H])C([H])([H])C2=C([H])C([H])=C(Cl)C([H])=C2[H])C([H])([H])C2=C([H])N=C([H])C([H])=C2[H])C([H])([H])C(=O)N(C(=O)[C@]2([H])N(C(=O)[C@@]([H])(N([H])C(=O)[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])C1=O)C([H])([H])C([H])([H])C([H])([H])N=C(N([H])[H])N([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])[H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C(=O)N([H])[H]
[H]N1C([H])([H])[C@]2([H])C3=C([H])C(=C([H])C([H])=C3[C@@]([H])(C([H])([H])[H])[C@]2([H])C1([H])[H])C([H])([H])[H]
[H]OC(=O)C([H])([H])OC1=C([H])C([H])=C(C([H])=C1[H])C1=NN2C(=N1)C1=C(N=C2N([H])[H])N(N=C1[H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N([H])C1=C(N([H])C2=C([H])C([H])=C(C(=O)C3=C(OC([H])([H])[H])C([H])=C([H])C([H])=C3[H])C(Cl)=C2[H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)C1=C(N(C(=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C([H])C([H])=C([H])C3=C([H])C([H])=C([H])N=C23)C([H])([H])C1([H])[H]
[H]N([H])C(=O)C1=C([H])C2=C(C([H])=C1[H])N(C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N([H])C([H])([H])C([H])([H])C1=C([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C([H])([H])C2([H])[H]
[H]C1=C([H])C([H])=C(S1)[C@@]1([H])C([H])([H])[C@]2([H])O[C@@]([H])(C([H])([H])C2([H])[H])[C@]1([H])C(=O)OC([H])([H])[H]
[H]N([H])[C@@]1([H])C2=C(SC(=C2[H])S(=O)(=O)N([H])[H])S(=O)(=O)C([H])([H])C1([H])[H]
[H]O[C@@]([H])(C([H])([H])C([O-])=O)C([H])([H])[C@]([H])(O[H])C([H])([H])C([H])([H])C1=C(C(=C(N1C([H])(C([H])([H])[H])C([H])([H])[H])C(=O)N([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=N1)C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]N([H])C1=C(C([H])=C(C([H])=N1)C1=C([H])N(N=C1[H])C1([H])C([H])([H])C([H])([H])N([H])C([H])([H])C1([H])[H])C1=NC2=C(O1)C([H])=C(C([H])=C2[H])C1=C([H])N=C([H])C([H])=C1[H]
[H]N(C(=O)N([H])C1=C([H])C([H])=C([H])C2=C1[C@@]1([H])N(C2=O)C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C1=NC([H])=C([H])C([H])=C1[H]
[H]N(C1=NC2=C(C([H])=N1)C([H])=C([H])C(=O)N2C([H])(C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC(=O)C(\[H])=C(/[H])C1=C([H])C([H])=C(N([H])C(=O)C2=C([H])C(N([H])C3=NC([H])([H])C([H])([H])C([H])([H])N3[H])=C([H])C([H])=C2[H])C(=C1[H])C([H])([H])C([H])([H])[H]
[H]OC(=O)[C@@]([H])(N([H])C(=O)[C@]([H])(N(C([H])([H])C1=C([H])N=C([H])N1C([H])([H])[H])S(=O)(=O)C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C(\[H])=C(/C([H])([H])[H])C([H])([H])C([H])([H])C(\[H])=C(/C([H])([H])[H])C([H])([H])C([H])([H])C([H])=C(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)C1=C([H])C([H])=C2N(C3=C(C([H])=C([H])C([H])=C3[H])C2=C1[H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C1=C([H])C([H])=NC([H])=C1[H]
[H]N(C(=O)N([H])[C@]([H])(C(=O)N1C([H])([H])C([H])([H])C([H])(N2C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H])C([H])([H])C(=O)N1C([H])([H])C([H])([H])C([H])(N2C(=O)N([H])C3=C(C([H])=C([H])C([H])=C3[H])C2([H])[H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C([H])C([H])=C1F
[H]N(C1=C([H])C([H])=C(OC2([H])C([H])([H])C([H])([H])N(C(=O)C([H])([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C2([H])[H])C(=C1[H])C([H])([H])[H])C1=NC([H])=NC2=C([H])C([H])=C(OC([H])([H])C([H])([H])C([H])([H])N3C([H])([H])C([H])([H])OC([H])([H])C3([H])[H])C([H])=C12
[H]O[C@@]([H])(C(=O)O[C@]1([H])C(=C2[C@@]([H])(O[H])C(=O)[C@]3(C([H])([H])[H])[C@@]([H])(O[H])C([H])([H])[C@@]4([H])OC([H])([H])[C@@]4(OC(=O)C([H])([H])[H])[C@@]3([H])[C@]([H])(OC(=O)C3=C([H])C([H])=C([H])C([H])=C3[H])[C@](O[H])(C1([H])[H])C2(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])[C@@]([H])(N([H])C(=O)OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C1=C(SC2=C([H])C(=O)N(C(=O)N12)C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C(=O)OC([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C1=C([H])C(=NC(=N1)C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)C([H])([H])[H])C(F)(F)F)C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1C([H])([H])C([H])([H])C2(OC(=O)C3=C2C([H])=C([H])C([H])=C3[H])C([H])([H])C1([H])[H]
[H]OC1=C2O[C@]3(C(=O)C([H])=C([H])[C@@]4(N([H])C(=O)C(\[H])=C(/[H])C5=C([H])C([H])=C(C([H])=C5[H])[N+]([O-])=O)[C@]5([H])N(C([H])([H])[H])C([H])([H])C([H])([H])[C@]34C2=C(C([H])=C1[H])C5([H])[H])C([H])([H])[H]
[H]N([H])C(=O)C1=C([H])N=C(N2C([H])([H])C([H])([H])N(C3=NC4=C(N3[H])C([H])=C([H])C(=C4[H])C(F)(F)F)C([H])([H])C2([H])[H])C(Cl)=C1[H]
[H]OC(=O)C(=C(/[H])C1=C(OC2=C([H])C([H])=C3N=C([H])C([H])=C([H])C3=C2[H])C2=C([H])C(OC([H])([H])C3=C([H])C([H])=C(C([H])=C3[H])C3=C([H])C([H])=C([H])C([H])=C3[H])=C(OC([H])([H])C3=C([H])C([H])=C(C([H])=C3[H])C3=C([H])C([H])=C([H])C([H])=C3[H])C([H])=C2S1)\C1=C([H])C([H])=NC([H])=C1[H]
[H]N([H])C1=C(N=C(C([H])=N1)C1=C([H])C(=C(C([H])=C1[H])S(=O)(=O)N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H])C([H])([H])[H])C(=O)N([H])C1=C([H])C([H])=C([H])N=C1[H]
[H]OC([H])([H])C([H])([H])N(C(=O)C1=C([H])C([H])=C(C([H])=C1[H])C(C1=C2N=C([H])C([H])=C([H])C2=C([H])C([H])=C1[H])=C1C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])SC([H])=N2)C([H])([H])C1([H])[H])C([H])([H])[H]
CCN(C)C(=O)C1=CN=C2N(CCCOC)C(NC(=O)C3=CC=CC(=C3)C#N)=NC2=C1
[H]OC(=O)C([H])([H])[C@]([H])(N([H])C(=O)C1=C(N([H])C(=O)N([H])C2=C(Cl)C([H])=C([H])C([H])=C2Cl)C([H])=C2C([H])=C([H])C([H])=C([H])C2=C1[H])C(=O)O[H]
[H]OC(=O)[C@]1([H])N([H])C2=C([H])C(Cl)=C([H])C(Cl)=C2[C@@]([H])(N2C(=O)C([H])([H])C([H])([H])C2([H])[H])C1([H])[H]
[H]N(C(=O)C([H])([H])[C@]1([H])N2C(=O)C(=O)N([H])C3=C([H])C(I)=C([H])C(=C23)C([H])([H])C1([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C1=C([H])C2=C(C([H])=C1[H])C([H])=C(C([H])=C2[H])C([H])([H])OC1=C(C(=C([H])C([H])=C1[H])C1(OC([H])([H])[H])C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C([H])([H])[H]
[H]C([H])=C([H])C(=O)N([H])C1=C(SC([H])([H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H])C([H])=C2N=C([H])N=C(N([H])C3=C([H])C(Br)=C([H])C([H])=C3[H])C2=C1[H]
[H]N1N=NC(=N1)C1=C([H])C2=C(OC3=C([H])C([H])=C(C([H])=C3[H])C3=C([H])C([H])=C(C([H])=C3[H])C(F)(F)F)C([H])=NC([H])=C2S1
[H]OC1=NC(=C(N1C1([H])C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H])C([H])([H])[H])C1=C([H])C(Cl)=C([H])C([H])=C1[H]
[H]OC(=O)[C@]([H])(N([H])C(=O)C1=C([H])C([H])=C(C([H])=C1[H])N(C([H])([H])[H])C([H])([H])C1=NC2=C(N=C(N=C2N=C1[H])N([H])[H])N([H])[H])C([H])([H])C([H])([H])C(=O)N([H])[C@@]([H])(C(=O)N([H])[C@@]([H])(C(=O)O[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])[H]
[H]N(C(=O)C1=C([H])C(F)=C([H])C(C#N)=C1[H])C1=C([H])C([H])=C([H])C(C#N)=C1[H]
[H]N([C@]([H])(C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)C1=C(C([H])=C(C([H])=C1[H])C1([H])C([H])([H])C1([H])[H])S(=O)(=O)C1=C([H])C([H])=C([H])C([H])=C1F)C([H])([H])[H])S(=O)(=O)C(F)(F)F
[H]SC([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@]([H])(N([H])C(=O)OC([H])([H])[H])C(=O)N([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
C[C@@H](CN1CCC2(CC1)N(CNC2=O)C1=CC=CC(C)=C1)NC(=O)C1=CC=C(Br)C=C1
[H]N([H])C1=NC([H])=NC(N2C([H])([H])C([H])([H])N(C(=O)N([H])C3=C([H])C([H])=C(C([H])=C3[H])C3([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C3([H])[H])C([H])([H])C2([H])[H])=C1\C([H])=N\OC([H])([H])[H]
[H]N(C(=O)C(\[H])=C(/[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]C1=C(C(=O)C(=O)N(C([H])([H])[H])C([H])([H])[H])C2=C([H])C(C(=O)N3C([H])([H])[C@@]([H])(N(C([H])([H])[C@@]3([H])C([H])([H])[H])[C@@]([H])(C#N)C3=C([H])C([H])=C(F)C([H])=C3[H])C([H])([H])[H])=C(Cl)C([H])=C2N1C([H])([H])[H]
[H]O[C@@]([H])(C(=O)N([H])C([H])([H])C1=C([H])C([H])=C(S1)C([H])([H])N1C(=NC2=C1C([H])=C([H])C([H])=C2[H])C([H])([H])[H])[C@@]([H])(O[H])C(=O)N1C([H])([H])C([H])([H])C([H])([H])[C@]1([H])C1=C([H])C(Cl)=C([H])C([H])=C1[H]
[H]OC(=O)[C@](OC([H])([H])[H])(C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(OC([H])([H])C([H])([H])C2=C(OC(=N2)C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])[H])N=C1[H]
[H]N(C(=O)C1=C([H])C2=C(S1)C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])C([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)C([H])([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C1=NC(=NO1)C1=C([H])C([H])=C(Cl)C([H])=C1[H])[C@@]1([H])[C@@]2([H])C([H])([H])[C@]3([H])C([H])([H])[C@]([H])(C2([H])[H])C([H])([H])[C@@]1([H])C3([H])[H]
[H]N([H])C1=NC([H])=NN2C([H])=C([H])C(C(=O)N([H])C3=C([H])C([H])=C(N([H])C(=O)N([H])C4([H])C([H])([H])C([H])([H])C([H])([H])C4([H])[H])C([H])=C3[H])=C12
OC(=O)C1=C(CCCOC2=CC=CC3=CC=CC=C23)C2=CC=C(Cl)C=C2S1
[H]N(C(=O)C1=C(N(C(=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C(Cl)C(Cl)=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N(C(=O)[C@]1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C(=O)N1C([H])([H])C([H])([H])N(C2=C([H])C([H])=C(OC([H])([H])[H])C([H])=C2[H])C([H])([H])C1([H])[H])C1(C#N)C([H])([H])C1([H])[H]
[H]C1=NC2=C(C([H])=C(C([H])=C2[H])C(=O)N2C([H])([H])C([H])([H])C([H])([H])[C@@]3([H])C4=C([H])C([H])=C([H])C([H])=C4C([H])([H])C([H])([H])[C@]23[H])N1C([H])([H])[H]
[H]N([H])C1=C([H])C([H])=C(OC2=C([H])C([H])=C(N([H])C(=O)N3C([H])([H])C([H])([H])N(C4=NC([H])=NC5=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C([H])=C45)C([H])([H])C3([H])[H])C([H])=C2[H])C([H])=C1[H]
[H]C1=C(ON=C1C([H])([H])[H])C([H])([H])N1C(=O)C2(C([H])([H])C([H])([H])N(C3=C([H])N=C4C([H])=C([H])C([H])=C([H])C4=N3)C([H])([H])C2([H])[H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(C(=O)C1=C([H])N(C2=C([H])C([H])=C(C([H])=C2C1=O)N1C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])[C@]12C([H])([H])[C@@]3([H])C([H])([H])[C@]([H])(C([H])([H])[C@]([H])(C3([H])[H])C1([H])[H])C2([H])[H]
[H]C1=NC([H])=C(N1C([H])([H])[H])[C@@]([H])(OC([H])([H])C1=C(C([H])=C(C#N)C([H])=C1[H])C1=C([H])C(OC([H])([H])[H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C(N=C1[H])C#N
[H]N(C(=O)[C@]1([H])N(C(=O)C2=C([H])C([H])=C([H])C(=C12)C([H])([H])[H])C([H])([H])C([H])([H])C1=NC([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C(OC(F)(F)F)C([H])=C1[H]
[H]OC1=C([H])C(=C(C(=C1[H])C([H])([H])[H])C([H])([H])[C@]([H])(N(C([H])([H])[H])C([H])([H])[H])C(=O)N1C([H])([H])C2=C(C([H])=C([H])C([H])=C2[H])C([H])([H])[C@@]1([H])C(=O)N([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=O)[C@@]1([H])N(C(=O)[C@@]([H])(N(C([H])([H])[H])C([H])([H])[H])C([H])([H])C2=C(C([H])=C(O[H])C([H])=C2C([H])([H])[H])C([H])([H])[H])C([H])([H])C2=C(C([H])=C([H])C([H])=C2[H])C1([H])[H])C([H])([H])[H]
[H]C1=C([H])C(=C([H])C([H])=C1Br)C([H])([H])[C@@]([H])(C(=O)N1C([H])([H])C2=C(C([H])=C(OC([H])([H])[H])C(OC([H])([H])[H])=C2[H])C([H])([H])C1([H])[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]N([H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N([H])C(=O)[C@@]1([H])N(C(=O)[C@]([H])(N([H])S(=O)(=O)C([H])([H])[H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(C(=O)C([H])([H])[H])C1=C([H])C([H])=C(Cl)C(=C1[H])N1N=C(N(C1=O)C([H])([H])C1=C(F)C([H])=C(C([H])=C1[H])C1=C([H])C(=C([H])C([H])=C1S(=O)(=O)N([H])C(=O)C1=C([H])C([H])=C([H])C([H])=C1Cl)C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]OC(=O)C([H])([H])[C@@]1([H])N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@]([H])(N([H])C(=O)[C@]([H])(N([H])[H])C([H])([H])SSC([H])([H])[C@@]([H])(N([H])C(=O)[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])C1=O)[C@]([H])(O[H])C([H])([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C(=O)N([H])[H])C([H])([H])C1=C([H])C([H])=C(O[H])C([H])=C1[H])C([H])([H])O[H]
[H]N(C(=O)O\N=C(/[H])C1=C([H])C([H])=C(F)C([H])=C1[H])C1=C([H])C([H])=C(OC([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])=C1[H]
[H]N1C(=O)N(C2=C(C(=C([H])C(=C2[H])C2([H])C([H])([H])C([H])([H])N([H])C([H])([H])C2([H])[H])C2=C([H])C([H])=C(F)C([H])=C2F)C1([H])[H])C1=C(Cl)C([H])=C([H])C([H])=C1Cl
[H]OC([H])([H])[C@]([H])(N([H])C(=O)C([H])([H])C([H])([H])C([H])([H])C(\[H])=C(\[H])C([H])([H])C(\[H])=C(\[H])C([H])([H])C(\[H])=C(\[H])C1=C([H])C([H])=C([H])C([H])=C1C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])[H]
[H]N([H])C1=C(C#N)C(C2=C([H])SC([H])=C2[H])=C(C#N)C(SC([H])([H])C(=O)C2=C([H])C([H])=C(Cl)C([H])=C2[H])=N1
[H]O[C@@]([H])(C([H])([H])[C@@]([H])(C(=O)N([H])[H])C1([H])C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])[C@@]([H])(N([H])C(=O)C1=NC2=C([H])C([H])=C([H])C([H])=C2N=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC([H])([H])C([H])(N([H])C([H])([H])C1=C([H])N([H])C2=C1N=C([H])N([H])C2=O)C([H])([H])O[H]
[H]N1C(=NC(=C1C1=C([H])C([H])=NC([H])=C1[H])C1=C([H])C([H])=C(Cl)C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N1C2=C([H])C([H])=C(C([H])=C2[C@]([H])(OC([H])([H])C1=O)C([H])([H])[H])C1=C([H])C([H])=C(C#N)N1C([H])([H])[H]
[H]C1=C([H])C(C2=NN3C4=C2N=C(C([H])=C4N(C([H])([H])C3([H])[H])C([H])(C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])[H])=C(Cl)C([H])=C1Cl
[H]N(\N=C1\C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C([H])([H])[H])C1=NC(=C([H])S1)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H]
Cc1cnc(Nc2ccccn2)nc1-c1c[nH]c(c1)C(=O)N[C@H](CO)c1cccc(Cl)c1
[H]OC1=C(C([H])=C(C([H])=C1C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C(=O)C([H])([H])N1C(=N[H])N(C2=C([H])C([H])=C([H])C([H])=C12)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])N(C([H])=N1)[C@]([H])(C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H]
[H]OC1=C([H])C([H])=C([H])C(=C1[H])[C@@]1([H])N([H])C(=S)N(C(=C1C(=O)C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])C2=C(N=C(S2)N2C([H])([H])C([H])([H])N(C([H])([H])C3=NC4=C([H])C([H])=C([H])C([H])=C4N3C([H])([H])[H])C([H])([H])C2([H])[H])C([H])=C1[H]
[H]OC(=O)C([H])([H])N([H])C(=O)C([H])([H])[C@@]1([H])O[C@@]([H])(C2=C([H])C(Cl)=C([H])C([H])=C2N2C([H])=C([H])C([H])=C12)C1=C(OC([H])([H])[H])C(OC([H])([H])[H])=C([H])C([H])=C1[H]
[H]O[C@@]1([H])C([H])([H])C(=O)O[C@@]([H])(C(\[H])=C(/[H])C2=C(OC([H])([H])C(\[H])=C(/[H])C3=C([H])C([H])=C([H])C([H])=C3[H])C([H])=C(Cl)C([H])=C2Cl)C1([H])[H]
[H]OC1=C([H])C([H])=C2C([H])=C(SC2=C1[H])C1=C([H])C([H])=C(O[H])C(=C1[H])C([H])([H])[H]
[H]C1=C([H])C(=C([H])C([H])=C1F)[C@@]([H])(N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H])C([H])([H])N1C([H])([H])C([H])([H])N(C([H])([H])[C@@]([H])(C(=O)C2=C([H])C([H])=C(C([H])=C2[H])[N+]([O-])=O)C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N=C(N([H])N([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C(=O)N([H])C1=C(C([H])=C([H])C([H])=C1[H])C(=O)N([H])C1=C([H])C([H])=C(Cl)C([H])=N1
[H]OC1=C([H])C([H])=C2N(C3=C(C2=C1[H])C1=C(C(=O)N([H])C1=O)C(=C3[H])C1=C(Cl)C([H])=C([H])C([H])=C1Cl)C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]OC(=O)[C@]([H])(OC1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1C2=C(N=C1C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])=C([H])C([H])=C2[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
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[H]OC(=O)[C@@]([H])(N([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C(=O)N1C([H])([H])C([H])([H])C([H])(C([H])([H])C([H])([H])C([H])([H])C2([H])C([H])([H])C([H])([H])N([H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]N1C(=O)C([H])([H])C([H])([H])[C@@]2(C([H])([H])[H])[C@]1([H])C([H])([H])[C@]([H])(C([H])([H])[H])[C@]1([H])[C@@]3([H])C([H])([H])C([H])([H])[C@@]([H])([C@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])[C@@]3(C([H])([H])[H])C([H])([H])C([H])([H])[C@@]21[H]
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[H]ON([H])C(=O)C(\[H])=C(/[H])C1=C([H])C2=C(N([H])C(=N2)C([H])([H])C([H])([H])C2=C([H])C([H])=C([H])N=C2[H])C([H])=C1[H]
[H]C1=C([H])C2=C(C([H])=C1[H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1=NC3=C([H])C([H])=C([H])C([H])=C3S1)C2([H])[H]
FC1=CC2=C(C=C1)N(CC2)C(=O)C12CC3CC(CC(C3)C1)C2
[H]O[C@]([H])([C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)C([H])([H])C(N([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])C([H])([H])C1=C([H])N([H])C([H])=N1)C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])[C@@]1([H])OC(=O)N(C([H])([H])C([H])([H])[H])C1([H])[H]
[H]OC([H])([H])[C@]1([H])C([H])([H])N(C([H])([H])C1([H])[H])[C@]1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])N(C(=O)C([H])([H])C1=C2C([H])=C([H])SC2=C([H])C([H])=C1[H])C([H])([H])[H]
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[H]N(C(=O)N(C([H])([H])[H])[C@]([H])(C([H])([H])[H])C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C(OC2=C([H])C([H])=C([H])C([H])=C2[H])C([H])=C1[H]
[H]OC1=C([H])C2=C(C([H])=C1O[H])C([H])([H])C([H])([H])[N+]1=C([H])C3=C(O[H])C(O[H])=C([H])C([H])=C3C([H])=C21
[H]N(C(=S)N([H])C([H])([H])C([H])([H])C([H])([H])OC([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C(=O)C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N([H])S(=O)(=O)N([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@]([H])(N([H])C(=O)OC([H])([H])C1=C([H])C([H])=C([H])C(Cl)=C1[H])C(=O)N([H])C1=NC(=C([H])S1)C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C1=C(Br)C(N(C2=NC(=NC(=N2)C([H])([H])[H])N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H])=C(OC([H])([H])[H])C([H])=C1OC([H])([H])[H]
[H]N(C(=O)C([H])([H])OC([H])([H])[H])C1=NN(C2=C1C([H])=C1C([H])=C(C([H])=C([H])C1=N2)C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]O[C@@](C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])(C([H])([H])[H])C(F)(F)F
[H]N(C(=O)[C@]1([H])N([H])C([H])([H])C2=C(C([H])=C([H])C([H])=C2[H])C1([H])[H])[C@@]([H])(C(=O)N1C([H])([H])C([H])([H])C(C([H])([H])N2C(=O)OC([H])([H])C2(C([H])([H])[H])C([H])([H])[H])(C([H])([H])C1([H])[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]O[C@@]12C([H])([H])[C@@]3([H])C([H])([H])[C@@]([H])(C1([H])[H])[C@@]([H])(N([H])C(=O)C1=NC(=C([H])N=C1N([H])[H])C1=C([H])C(=C([H])C([H])=C1[H])C1=C([H])N(N=C1[H])C([H])([H])[H])[C@]([H])(C3([H])[H])C2([H])[H]
[H]C1=C([H])C([H])=C(N2C([H])([H])C([H])([H])N(C([H])([H])C2([H])[H])[C@@]2([H])C([H])([H])C([H])([H])[C@]([H])(N3C(=O)C4=C(C3=O)C3=C([H])C([H])=C([H])C([H])=C3C([H])=C4[H])C([H])([H])C2([H])[H])C(OC([H])(C([H])([H])[H])C([H])([H])[H])=C1[H]
[H]N(C(=O)N([H])C([H])([H])C(C1=C([H])C([H])=C([H])C([H])=C1[H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C(C([H])=C([H])C([H])=C1C([H])(C([H])([H])[H])C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N1C([H])([H])C([H])([H])[C@]([H])(C2=C([H])C([H])=C(Cl)C([H])=C2[H])[C@]([H])(C2=NC(=NO2)C([H])([H])[H])C1([H])[H]
[H]OC1=C(Br)C([H])=C(C([H])=C1Br)C([H])([H])N1C2=C(N=C1C([H])([H])C([H])([H])[H])C(=C([H])C(=N2)C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)C1=C([H])N=C(C([H])=C1[H])C1=C(C([H])=C([H])C([H])=N1)C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C(F)(F)F
[H]O[C@@]([H])(C([H])([H])C(=O)N1C([H])([H])C([H])([H])O[C@]([H])(C([H])([H])C([H])([H])N([H])[H])C1([H])[H])[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(C([H])([H])C(=O)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C2=C([H])C([H])=C([H])C([H])=C12)C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])C(\S[H])=N\C([H])([H])[H])C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(C(=O)C1(C(=O)N([H])C2=C([H])C([H])=C(OC3=C([H])C([H])=NC4=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C([H])=C34)C(F)=C2[H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]OC1=NC2=C(C3=C([H])C([H])=C([H])C([H])=C13)C([H])([H])C([H])([H])N([H])C2([H])[H]
[H]\C(=N/C1=C([H])C([H])=C(C([H])=C1[H])C(F)(F)F)C1=C([H])N(C2=C([H])C([H])=C([H])C([H])=C12)C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N=C(N([H])[H])C1=C([H])C(=C([H])C([H])=C1[H])C(=C(\[H])C(=O)N([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1S(=O)(=O)N([H])[H])\C([H])([H])OC([H])([H])[H]
[H]N=C(N([H])[H])N([H])C([H])([H])C([H])([H])C([H])([H])[C@@]([H])(N([H])C(=O)[C@@]1([H])N(C(=O)[C@@]2([H])N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@]([H])(N([H])C(=O)C([H])([H])C([H])([H])SSC2([H])[H])C([H])(C2=C([H])C([H])=C([H])C([H])=C2[H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C(=O)N([H])[H])C([H])([H])C(=O)N([H])[H])C([H])([H])C([H])([H])C1([H])[H])C(=O)N([H])C([H])([H])C(=O)N([H])[H]
[H]N(C1=NC2=C(N=NN2C2=C1SC([H])=C2[H])S(=O)(=O)C1=C([H])C([H])=C([H])C(Cl)=C1[H])C([H])([H])C1=C(OC([H])([H])[H])C([H])=C([H])C([H])=C1[H]
[H]N1N=C([H])C2=C1C(=C([H])C(=C2[H])C(=O)N1C([H])([H])C([H])([H])C2(OC3=C(C([H])=C(C([H])=C3[H])C3=NN([H])C(=C3[H])C([H])([H])[H])C(=O)C2([H])[H])C([H])([H])C1([H])[H])C([H])([H])[H]
[H]C1=C([H])C(F)=C2N(C(=C(C(=O)C3=C([H])C([H])=C(OC([H])([H])[H])C([H])=C3[H])C2=C1[H])C([H])([H])[H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]OC1=C(C([H])=C([H])C(OC([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C(=O)N([H])C2([H])C([H])([H])C2([H])[H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]N(C1=NC(=NC(=N1)N([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C(C2=C([H])N=C([H])O2)C(OC([H])([H])[H])=C1[H]
[H]N1C([H])([H])C([H])([H])N(C2=C3OC([H])=C([H])C3=C([H])C([H])=C2C#N)C([H])([H])C1([H])[H]
[H]OC(=O)C([H])([H])OC([H])([H])C(\[H])=C1\C([H])([H])[C@@]2([H])C([H])([H])[C@]([H])(O[H])[C@]([H])(C#C[C@]([H])(O[H])[C@]([H])(C([H])([H])[H])C([H])([H])C#CC([H])([H])C([H])([H])[H])[C@@]2([H])C1([H])[H]
[H]OC(=O)[C@@]([H])(N([H])C(=O)OC([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C(OC([H])([H])C([H])([H])C([H])([H])C2([H])C([H])([H])C([H])([H])N([H])C([H])([H])C2([H])[H])C([H])=C1[H]
[H]C1=C([H])C(O[C@@]2([H])C(=O)C3=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C([H])=C3C2([H])[H])=C([H])C(=C1[H])C(=O)C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H]
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[H]N(C(=O)C([H])([H])[C@@]([H])(N([H])C(=O)C1=C([H])C([H])=C(C([H])=C1[H])C1=NC([H])([H])C([H])([H])N1C([H])([H])[H])C(=O)N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C(Br)C([H])=N1
[H]C1=NC([H])=C([H])C(=C1[H])C([H])([H])N(C([H])([H])[H])[C@@]1([H])C([H])([H])N(C2=NN=C(C([H])=C2[H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N(C1=NC2=C([H])C([H])=C([H])C([H])=C2C(=O)O1)C([H])([H])C([H])([H])C([H])([H])[H]
[H]N(N1C2=C([H])C([H])=C(Cl)C([H])=C2N=C(N2C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C2([H])[H])C2=C1C([H])=C([H])C([H])=C2[H])C(=O)C1=C(C([H])=C([H])S1)C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N1C(=O)N(C(=C1C([H])([H])S(=O)(=O)C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H])C([H])([H])C([H])([H])[H]
[H]N=C(N1C(=N[H])C([H])=C([H])C2=C1C([H])=C(C1=C([H])C([H])=C([H])C([H])=C1[H])C(=N2)C1=C([H])C([H])=C(C([H])=C1[H])C1(N([H])[H])C([H])([H])C(F)(F)C1([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC1=C([H])C([H])=C(C([H])=C1[H])C1=NC2=C([H])C(O[H])=C([H])C(=C2O1)C([H])(C([H])([H])[H])C([H])([H])[H]
[H]OC(=O)C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C1=C(SC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C2=C([H])C(OC([H])([H])C3=NC(Cl)=C([H])C([H])=C3[H])=C([H])C([H])=C2N1C([H])([H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]C1=C(C2=C([H])C([H])=C(Cl)C([H])=C2N1C1=C([H])C([H])=C([H])C([H])=C1[H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])N2C(=O)N(C([H])([H])C2([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N(C([H])([H])C([H])([H])OC1=C([H])C(F)=C([H])C2=C1OC([H])([H])C([H])([H])C2=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1OC([H])([H])[H]
[H]N([H])C1=NOC2=C([H])C([H])=C(C([H])=C12)N1N=C(C([H])=C1C(=O)[C@@]([H])(C1=C([H])C([H])=C(C([H])=C1F)C1=C([H])C([H])=C([H])C([H])=C1S(=O)(=O)N([H])[H])C([H])([H])[H])C(F)(F)F
[H]N(C1=C([H])C(=O)N(C2=C1C([H])=NN2C1=C(F)C([H])=C([H])C([H])=C1F)C([H])([H])[H])C1=C([H])C(=C([H])C([H])=C1C([H])([H])[H])C(=O)N([H])C1([H])C([H])([H])C1([H])[H]
[H]OC1=C([H])C([H])=C([H])C(=C1[H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1([H])C([H])([H])C1([H])[H]
[H]C1=C([H])C(=C([H])C2=C1OC([H])([H])O2)C1=C(C2=C(N1C1=C([H])C([H])=C(Cl)C([H])=C1Cl)C([H])([H])C([H])([H])N(C2=O)C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])[H]
[H]OC1=C(Br)C([H])=C(C([H])=C1Br)C([H])([H])C(=O)C1=C(OC2=C1C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])[H]
[H]N(C(=O)C1=C([H])C2=C(S1)C([H])=C([H])C(Cl)=C2[H])C([H])([H])C([H])([H])C([H])([H])N1C([H])=NC([H])=C1[H]
[H]N(C(=O)N([H])[C@]1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])[C@]([H])(C([H])([H])C2=C([H])C([H])=C(F)C([H])=C2[H])C1([H])[H])C1=C([H])C([H])=C([H])C(C#N)=C1[H]
[H]N1C(=O)C([H])([H])C([H])([H])C2=C([H])C(=C([H])C([H])=C12)[C@@]([H])(N1C([H])=NC([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]ON([H])C(=O)C([H])([H])N(C(=O)N([H])C1=C([H])C([H])=C(Cl)C(Cl)=C1[H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])[N+]([O-])=O
[H]N(C(=O)[C@]([H])(OC1=C([H])C(=O)OC2=C1C([H])=C([H])C([H])=C2[H])C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])N1C(=O)C([H])([H])OC([H])([H])C1([H])[H]
[H]N(C([H])([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[C@@]1([H])C2=C([H])C([H])=C(OC([H])([H])[H])C([H])=C2OC([H])([H])C1([H])[H]
[H]N=C(N(C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C(=O)N([H])C1=C(C([H])=C(Cl)C([H])=C1[H])C(=O)N([H])C1=C([H])C([H])=C(C([H])=N1)C([H])([H])[H]
[H]C1=NC([H])=C([H])C(=C1[H])C1=C([H])C(=O)N2C([H])([H])[C@]([H])(O[C@@]([H])(C3=C([H])C(=C([H])C(=C3[H])C(F)(F)F)C(F)(F)F)C([H])([H])[H])[C@@]([H])(C3=C([H])C([H])=C(F)C([H])=C3[H])[C@]2([H])C1([H])[H]
[H]ON([H])C(=O)[C@]1([H])N(C([H])([H])C([H])([H])S(=O)(=O)C1(C([H])([H])[H])C([H])([H])[H])S(=O)(=O)C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]N(C([H])(C([H])([H])[H])C([H])([H])[H])S(=O)(=O)C1=C(C([H])=C([H])C(=C1[H])C(=O)N1C([H])([H])C([H])([H])[C@]2([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@@]2([H])C1([H])[H])C([H])([H])[H]
[H]N1C(=O)C([H])([H])S[C@]([H])(C2=C([H])C([H])=C([H])C([H])=C2[H])C1([H])[H]
[H]ON(C(=O)N([H])[H])C([H])([H])C1=C([H])C2=C([H])C(OC([H])([H])C3=C([H])C([H])=C([H])C([H])=C3[H])=C([H])C([H])=C2O[C@]1([H])C([H])([H])[H]
[H]OC1=C(Br)C(C#N)=C([H])C([H])=C1N([H])C(=O)N([H])C1=C(Br)C([H])=C([H])C([H])=C1[H]
[H]N(C1=C2N=C(OC2=NC([H])=N1)C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]C1=C([H])C(=C([H])C(=C1C1=C([H])C(=C([H])C(=C1[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])OC(=O)C([H])([H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]N(C(=O)C1=C([H])N(C2=C([H])C(SC3=C([H])C([H])=C([H])C([H])=C3[H])=C([H])C([H])=C2C1=O)C([H])([H])C([H])([H])[H])[C@]1([H])C(C([H])([H])[H])(C([H])([H])[H])[C@@]2([H])C([H])([H])C([H])([H])[C@]1(C([H])([H])[H])C2([H])[H]
[H]N(C(=O)N1C([H])([H])C([H])([H])C([H])([H])[C@]1([H])C(=O)N([H])[C@@]([H])(C(=O)N(C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C(Cl)C(Cl)=C1[H])C1=C(C([H])=C([H])C([H])=C1[H])[N+]([O-])=O
[H]N([H])C([H])([H])C1=C(N=C(C(=C1C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H])C([H])([H])C(=O)N([H])C1=C([H])C(=C([H])C([H])=C1[H])[S@](=O)C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)C1=C(N=C2N=C(N([H])N2[C@]1([H])C1=C([H])C([H])=C(C([H])=C1[H])[N+]([O-])=O)C(=O)OC([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]ON([H])C(=N[H])C1=C([H])C([H])=C([H])C(=C1[H])[C@]1([H])OC2=C([H])C([H])=C([H])C([H])=C2N(C1=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N1[C@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C([H])([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)N1C([H])([H])C([H])([H])N(C(=O)C([H])([H])N2C(=O)OC3=C2C([H])=C(Cl)C([H])=C3[H])[C@]([H])(C([H])([H])N2C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C1([H])[H]
[H]OC(=O)[C@]([H])(N([H])C(=O)C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)N([H])[H])C([H])([H])C1=C([H])C([H])=C(O[H])C(O[H])=C1[H]
ClC1=CC=C(C(Cl)=C1)S(=O)(=O)NC1=CC(Cl)=C(OC2=CC3=CC=CN=C3C=C2)C(Cl)=C1
[H]ON([H])C(=O)C([H])([H])OC1=C([H])C([H])=C2C(=C1[H])C([H])([H])N(C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])[C@@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])[H])[C@]([H])(C(=O)N([H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])C2([H])[H]
[H]N([H])S(=O)(=O)C1=C([H])C(I)=C(N([H])S(=O)(=O)C2=C(F)C(F)=C(F)C(F)=C2F)C([H])=C1[H]
[H]C1=NC(OC2=C([H])C(Br)=C([H])C([H])=C2[H])=C2C([H])=C([H])C([H])=C([H])C2=N1
CCC1CCCCN1C(=O)\C=C\C1=C(/C=C/C2=CC=C(OC)C=C2)C=C(OC)C=C1OC
[H]OC1=C2C(OC(=C2C([H])([H])[H])C([H])([H])C2=C([H])C([H])=C(OC([H])([H])[H])C([H])=C2[H])=C(C([H])=C1C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])[H]
[H]OC(=O)C([H])([H])[C@]([H])(N([H])C(=O)[C@]([H])(N1C([H])=C([H])N=C(N([H])C([H])([H])C2=C([H])C(=NO2)C([H])([H])[H])C1=O)C([H])([H])C([H])([H])[H])C(=O)C([H])([H])SC([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC(=O)C([H])([H])C([H])([H])C1=C([H])C([H])=C(C2=NN=C(S2)C2=C([H])C(C#N)=C(OC(=O)C([H])([H])[H])C([H])=C2[H])C(=C1[H])C([H])([H])[H]
[H]OC([H])([H])[C@@]([H])(O[H])C([H])([H])OC1=C([H])C([H])=C(C([H])=C1C([H])([H])[H])C(C1=C([H])C(=C(OC([H])([H])[C@]([H])(O[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])=C1[H])C([H])([H])[H])(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H]
[H]N1C(=O)N(C2=C1C([H])=C([H])C([H])=C2[H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])SC3=C([H])C([H])=C([H])C([H])=C23)C([H])([H])C1([H])[H]
[H]OC1=C([H])C([H])=C(C([H])=C1[H])C1=C(C2=C([H])C([H])=C(O[H])C([H])=C2C1([H])[H])C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]C([H])([H])N1C2=C(N3C(=N2)N(C([H])([H])C([H])([H])C3([H])[H])C2([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C(=O)N(C1=O)C([H])([H])[H]
[H]N1C([H])=NC(=C1[H])C([H])([H])N1C([H])=C(C(=O)N2C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])C(=C1[H])C1=C2C([H])=C([H])C([H])=C([H])C2=C([H])C([H])=C1[H]
CC1=CC(Cl)=C(OCCOC2=CC=C(CC(CN)C3=C(F)C=C(C=C3)C3=C(Cl)C=CC=C3)C=C2)C(Cl)=C1
[H]C1=C(N=C(N1C1=C([H])C([H])=C(OC([H])([H])C([H])([H])[H])C([H])=C1[H])[C@]([H])(N(C(=O)C([H])([H])C1=C([H])C([H])=C(F)C(=C1[H])C(F)(F)F)C([H])([H])C([H])([H])OC([H])([H])C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OP(=O)(O[H])OC([H])([H])[C@@](N([H])[H])(C([H])([H])[H])C([H])([H])C([H])([H])C1=C([H])C([H])=C(N1C([H])([H])[H])C(=O)C([H])([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H]
OCCC(NC(=O)NC1=CC=C(C=C1)C1=CNN=C1)C1=CC=CC(F)=C1
[H]\C(=C1\C(=O)ON=C1C1=C(F)C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])N1C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]OC(=O)C1=C([H])C([H])=C([H])C([H])=C1[C@@]([H])(OC([H])([H])[C@]([H])(O[H])C([H])([H])N([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C2C([H])=C([H])C([H])=C([H])C2=C1[H])C([H])([H])[H]
[H]N(C1=NOC(=C1SC1=C([H])C(OC([H])([H])[H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])[H])S(=O)(=O)C1=C([H])C([H])=C(C([H])=C1[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]OC([H])([H])C(=O)[C@@]1(OC(=O)N([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])[C@@]([H])(C([H])([H])[H])C([H])([H])[C@@]2([H])[C@]3([H])C([H])([H])C([H])([H])C4=C([H])C(=O)C([H])=C([H])[C@]4(C([H])([H])[H])[C@@]3(F)[C@@]([H])(O[H])C([H])([H])[C@]12C([H])([H])[H]
[H]OC(=O)C([H])([H])N([H])C(=O)C(\[H])=C(/[H])C1=C([H])C([H])=C([H])C([H])=C1SC1=C(Cl)C([H])=C(Cl)C([H])=C1[H]
[H]OP(=O)(O[H])[C@]([H])(N([H])[C@]([H])(C1=NN([H])N=N1)C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])C2=C(OC([H])([H])O2)C([H])=C1[H]
[H]OC(=O)C1=C([H])C([H])=C([H])C(=N1)C(=O)N([H])C1=NN=C(S1)S(=O)(=O)N([H])[H]
[H]OC(=O)[C@@]([H])(N([H])[H])C([H])([H])SC(C1=C([H])C([H])=C(Cl)C([H])=C1[H])(C1=C([H])C([H])=C(Cl)C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]O[C@@]1([H])C([H])([H])C(=O)O[C@@]([H])(C(\[H])=C(/[H])C2=C(Cl)C([H])=C([H])C([H])=C2Cl)C1([H])[H]
[H]OC1=C2C(=C([H])C([H])=C1Br)[C@@]([H])(O[C@]([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C2([H])[H])C([H])([H])N([H])[H]
[H]N1C2=C(C(=NN2C([H])([H])[H])C2([H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])[H])C([H])([H])C2([H])[H])C2=C([H])C([H])=C([H])C([H])=C2C1=O
[H]ON1C(=O)[C@]([H])(N([H])S(=O)(=O)C2=C([H])C([H])=C(C([H])=C2[H])N2C([H])([H])C([H])([H])C([H])(C3=C([H])C([H])=C([H])C([H])=C3[H])C([H])([H])C2([H])[H])C([H])([H])C([H])=C([H])C1([H])[H]
[H]N1C([H])=C(C2=C1C([H])=C([H])C(F)=C2[H])C([H])([H])C([H])([H])C([H])([H])N(C1([H])C([H])([H])C([H])([H])C1([H])[H])[C@]1([H])C([H])([H])OC2=C(F)C([H])=C([H])C(C(=O)OC([H])([H])[H])=C2C1([H])[H]
[H]N1C([H])=C(C2=C1C([H])=C([H])C(OC([H])([H])[H])=C2[H])C1=C(C(=O)N([H])C1=O)C1=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C(OC([H])([H])[H])=C1[H]
[H]C1=NC([H])=C([H])C(=C1[H])C([H])([H])[C@]1([H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2C([H])([H])C1([H])[H]
[H]N(C1=C([H])C(=C([H])C([H])=N1)C1=C(N=C(SC([H])([H])[H])N1[H])C1=C([H])C(=C([H])C([H])=C1[H])C(F)(F)F)[C@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
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[H]ON([H])C(=O)C(\[H])=C(/[H])C1=C([H])C([H])=C([H])C(=C1[H])C(=O)C1=C([H])C2=C(O1)C([H])=C([H])C([H])=C2[H]
[H]OC1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N([H])C1=C([H])C([H])=C(C([H])=C1[H])N(C([H])([H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C1([H])C([H])([H])C([H])([H])N(C(=O)[C@@]([H])(N([H])C(=O)N2C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N(C1=NC([H])=C([H])C(=N1)N([H])C1=C([H])C2=C([H])C([H])=C([H])C([H])=C2N=C1[H])C1=C([H])C(OC(F)(F)F)=C([H])C([H])=C1[H]
COC1=CC=C(C=C1)S(=O)(=O)N1CCCNCC1C(=O)NO
[H]N([H])[C@@]1([H])C([H])([H])N(C2=NC([H])=NC(=N2)N2C([H])([H])C([H])([H])C(F)(F)C2([H])[H])C([H])([H])[C@]1([H])N1C(=O)C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(C1=C([H])C(OC([H])([H])[H])=C(Cl)C([H])=C1Cl)C1=C(C#N)C([H])=NC2=C([H])C([H])=C(C#CC([H])([H])C([H])([H])N3C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C3([H])[H])C([H])=C12
[H]N([H])C(=O)C1=NN([H])C2=C1C([H])([H])C([H])([H])C1=C([H])N=C(N=C21)N([H])C1=C(OC(F)(F)F)C([H])=C([H])C(=C1[H])N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H]
[H]O[C@@](C1=C([H])C([H])=C([H])C([H])=N1)(C1=C([H])C(F)=C([H])C(OC([H])([H])C2=C([H])C([H])=C3C(OC(=O)C([H])=C3C3=C([H])OC([H])=C3[H])=C2[H])=C1[H])C([H])([H])C([H])([H])[H]
[H]C1=C([H])C(=NN1C1=C([H])C(Cl)=C(C([H])=C1[H])C(=O)N1C2=C([H])C([H])=C([H])C([H])=C2N(C2=C(C([H])=C([H])C([H])=N2)C1([H])[H])C([H])([H])[H])C([H])([H])[H]
FC(F)(F)C1=CC=CC=C1OC1=CC=C(C=C1)C1=NC2=CC(=CC=C2N1)C(=O)NCCC1CC1
[H]N1C([H])=C(C2=C1C([H])=C([H])C(C([H])=O)=C2[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C([H])C([H])=C3OC([H])([H])C([H])([H])OC3=C2[H])C([H])([H])C1([H])[H]
[H]N([H])C1=C([H])C([H])=C([H])C([H])=C1C1=NN=C(O1)C(=O)N([H])C1=C([H])C(=C([H])C([H])=C1[H])N1C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(C(=O)C1=NN(C2=C(OC([H])([H])[H])C([H])=C([H])C([H])=C12)C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])[C@@]1([H])[C@@]2(C([H])([H])[H])C([H])([H])C([H])([H])[C@]([H])(C2([H])[H])C1(C([H])([H])[H])C([H])([H])[H]
[H]O[C@]1(C(=O)N([H])C2=C([H])C([H])=C([H])C3=C([H])C([H])=C(N=C23)C([H])([H])[H])C([H])([H])C([H])([H])[C@]([H])(N([H])C([H])([H])C2=NC([H])=C3OC([H])([H])C([H])([H])OC3=C2[H])C([H])([H])C1([H])[H]
[H]N([H])C1=C2C([H])=C(OC([H])([H])[H])C(OC([H])([H])[H])=C([H])C2=NC(=N1)N1C([H])([H])C([H])([H])C2=C(C([H])=C(OC([H])([H])[H])C(OC([H])([H])[H])=C2[H])[C@]1([H])C([H])([H])C1=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]N(C(=O)OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])=O
[H]C1=C(O[C@]2(C1=O)C([H])([H])N(C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C2([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])(N(C(=O)N([H])C([H])([H])C2=C([H])C([H])=C(F)C([H])=C2[H])C2=C([H])C([H])=C(Cl)C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N(C(=O)C([H])([H])C([H])([H])C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C(N2C(=N1)N(C([H])=C(C(=O)OC([H])(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H])C2=O)C([H])([H])C1=C(F)C([H])=C([H])C([H])=C1[H])C([H])([H])N(C([H])([H])[H])C([H])([H])C#N
[H]C1=NC(Cl)=C(N1C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)C([H])([H])[H])C1=C([H])C(F)=C(OC([H])([H])[H])C([H])=C1[H]
[H]C([H])=C([H])C([H])([H])N([H])[C@]1([H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[C@@]([H])(C2=C([H])C([H])=C([H])C([H])=C2[H])C1([H])[H]
[H]OC(=O)[C@]([H])(N([H])C(=O)C([H])([H])C([H])([H])[C@]([H])(N([H])C(=O)C1=C([H])C(Cl)=C([H])C(Cl)=C1[H])C(=O)N1C([H])([H])C([H])([H])C2(C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
COC1=CC=C(\C=C\C=C\C(=O)C2=CC=CC=C2O)C=C1
[H]N([H])C1=C([H])C(=NC([H])=N1)N1C(=NC2=C1C([H])=C([H])C([H])=C2[H])N([H])C1=C([H])C(N([H])C(=O)C2=C([H])C(Cl)=C(C([H])=C2[H])C([H])([H])N2C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])[H])C([H])([H])C2([H])[H])=C([H])C([H])=C1C([H])([H])[H]
[H]N(C1=C2C([H])=C(C([H])=C([H])C2=NC([H])=N1)C1=C([H])C([H])=C([H])O1)C([H])([H])C1=C([H])OC([H])=C1[H]
[H]OC([H])([H])C([H])([H])N([H])C(=O)C1=C2SC(=C([H])C2=C(N=C1[H])N([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)N([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]OC1=C2C([H])=C(C3=C([H])N=C([H])O3)C(OC([H])([H])[H])=C([H])C2=NC(=C1[H])C1=NC([H])=C([H])C([H])=C1[H]
[H]OC(=O)[C@]([H])(OC1=C(C2=C(C([H])=C1C([H])([H])C([H])([H])C([H])([H])[H])C(=NO2)C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C1=C([H])C(=C([H])N2C1=NC(=C2C([H])([H])[H])C([H])([H])[H])N1N=C([H])N=C1[H])[C@@]1([H])C2=C(C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]C1=C([H])C([H])=C(C(=C1[H])N(C(=O)C([H])([H])C([H])([H])C1=NC(=NO1)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])[H]
[H]N1C2=C(C3=C(C([H])=C2[H])C2=C([H])C(=C([H])C([H])=C2OC3([H])[H])[N+]([O-])=O)[C@]([H])(C([H])([H])[H])C([H])([H])C1(C([H])([H])[H])C([H])([H])[H]
[H]N(C1=NC2=C(SC([H])=C2[H])C(=N1)C(=O)C1=C([H])N=C([H])S1)C([H])([H])C1=C([H])C([H])=C([H])N=C1[H]
[H]N(C(=O)C([H])=C(C([H])([H])[H])C([H])([H])[H])[C@]1([H])C(=O)C2=C([H])C([H])([H])[C@@]3([H])[C@]4([H])C([H])([H])C([H])([H])[C@]([H])([C@@]([H])(N([H])C([H])([H])[H])C([H])([H])[H])[C@@]4(C([H])([H])[H])C([H])([H])C([H])([H])[C@]3([H])[C@@]2(C([H])([H])[H])C([H])([H])C1([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C1=NN(C(=O)C(N2C([H])([H])C([H])([H])N(C3=C(OC([H])([H])[H])C([H])=C([H])C([H])=C3[H])C([H])([H])C2([H])[H])=C1C(=O)C([H])([H])[H])C([H])([H])[H]
[H]OC([H])([H])C1=C([H])C([H])=C([H])C(=C1[H])C1=C(OC([H])([H])C([H])([H])[C@]2([H])N([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C2=C([H])C(C3=C([H])N(N=C3[H])C([H])([H])[H])=C(Cl)C([H])=C2N=C1[H]
[H]N1C2=C([H])C([H])=C([H])C([H])=C2C(C(=O)C(\C#N)=C2/S\C(=C(\[H])C3=C([H])C([H])=NC([H])=C3[H])C(=O)N2C2=C([H])C([H])=C(C([H])=C2[H])C([H])([H])[H])=C1C([H])([H])[H]
[H]N([C@]1([H])C([H])([H])C([H])([H])[C@@](C(=O)N2C([H])([H])C([H])([H])N(C3=NC([H])=C([H])C(=C3[H])C(F)(F)F)C([H])([H])C2([H])[H])(C([H])([H])OC([H])([H])C([H])([H])[H])C1([H])[H])[C@@]1([H])C([H])([H])C([H])([H])OC([H])([H])[C@@]1([H])OC([H])([H])[H]
[H]N(C(=O)[C@@]([H])(N([H])C(=O)C([H])([H])C1=C([H])N=C([H])N1[H])C([H])([H])OC([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C(OC2([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])=C1[H]
[H]O[C@@](C1=NC2=C([H])C([H])=C([H])C([H])=C2S1)(C1=C([H])C([H])=C2C([H])=C([H])C([H])=C([H])C2=C1[H])C([H])([H])[H]
[H]OC1=C([H])C([H])=C2C(=C1[H])[C@@]1(C([H])([H])[H])C([H])([H])C([H])([H])N(C([H])([H])C(OC([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])[C@]([H])(C2([H])[H])[C@]1([H])C([H])([H])[H]
[H]N(C1=NN([H])C([H])=C1[H])C1=C(N2N=C([H])C([H])=C([H])C2=N1)C1=NC(=NC(N([H])C2=C([H])N=C([H])C([H])=N2)=C1[H])C([H])([H])[H]
[H]N=C(N([H])[H])C1=C([H])C([H])=C2N(N=C([H])C2=C1[H])C([H])([H])C(=O)N1C([H])([H])C([H])([H])C([H])(C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]C1=NC(=C([H])C([H])=C1[H])C1=NC2=C(C([H])=C([H])C(F)=C2[H])N1C1=C([H])C([H])=C(OC([H])([H])C([H])([H])C([H])([H])N2C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C2([H])[H])C([H])=C1[H]
[H]N=C(N([H])[H])C1=C([H])C(OC2=C(C([H])=C(Cl)C([H])=C2[H])C(=O)N([H])C2=C([H])C([H])=C(C([H])=C2[H])C2=C([H])C([H])=C([H])C([H])=C2S(=O)(=O)N([H])[H])=C([H])C([H])=C1[H]
[H]N=C(N([H])[H])N([H])C([H])([H])C([H])([H])C([H])([H])[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)C1=NN([H])C(=N1)N([H])[H])C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C(=O)N([H])[C@]([H])(C(=O)N([H])[H])C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(C(=O)N1C([H])([H])C([H])([H])C([H])(C2=NC([H])=C([H])C([H])=C2C(F)(F)F)C([H])([H])C1([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C(F)(F)F
[H]OC([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])C1(C(=O)N([H])C(=O)N([H])C1=O)C1=C([H])C([H])=C(OC2=C([H])C([H])=C(OC([H])([H])[H])C([H])=C2[H])C([H])=C1[H]
[H]N(C1=C([H])C([H])=NC([H])=C1[H])C1=C([H])C2=C(C([H])=C1[H])C([H])([H])[C@]1([H])N(C([H])([H])C3([H])C([H])([H])C3([H])[H])C([H])([H])C([H])([H])[C@@]2(C([H])([H])[H])[C@@]1([H])C([H])([H])[H]
[H]N1C([H])=C([H])C2=C3O[C@@]([H])(C([H])([H])N4C([H])([H])C([H])([H])C5(N(C6=C([H])C([H])=C([H])C([H])=C6[H])C([H])([H])N([H])C5=O)C([H])([H])C4([H])[H])C([H])([H])OC3=C([H])C([H])=C12
[H]N(C(=O)C1=C([H])C(Br)=C([H])S1)C([H])([H])C([H])([H])C1=C([H])C([H])=C(OC([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H])C(Br)=C1[H]
[H]N=C(N([H])[H])C1=C([H])SC(=C1[H])C([H])([H])N1C(=O)[C@@]([H])(N([H])S(=O)(=O)C2=C([H])C3=C(C([H])=C([H])C(OC([H])([H])[H])=C3[H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]OC(=O)[C@]([H])(C([H])([H])C([H])([H])N1C(=O)C2=C(C([H])=C3C([H])=C([H])C([H])=C([H])C3=C2[H])C1=O)C([H])([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)C1=C(C([H])=C(N([H])C([H])([H])C2=C([H])N=C([H])N2C([H])([H])C2=C([H])C([H])=C(C#N)C([H])=C2[H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N1C([H])([H])C([H])([H])[C@]([H])(N2C([H])=C(C3=C([H])C([H])=C([H])N=C23)S(=O)(=O)C2=C([H])C(Br)=C([H])C([H])=C2[H])C1([H])[H]
[H]N1C(=NC(=C1C1=C([H])C(F)=C(F)C(F)=C1[H])C1=C([H])C(F)=C(F)C(F)=C1[H])N1C([H])([H])C([H])([H])N(C2=C(C([H])=C([H])C([H])=N2)C(F)(F)F)C([H])([H])C1([H])[H]
[H]OC(=O)C1=C(N=C(N1C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C(C([H])=C([H])C([H])=C1[H])C1=NN([H])N=N1)C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])[C@@]1([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N([H])[C@@]1([H])C([H])([H])N(C(=O)N([H])C([H])([H])C2=C([H])C(F)=C([H])C([H])=C2[H])C([H])([H])[C@]1([H])C1=C([H])C([H])=C(Cl)C([H])=C1Cl
[H]N([H])C1=NC([H])=C2C([H])=C(C(=O)N(C2=N1)C([H])([H])C([H])([H])C([H])([H])[H])C1=C(Cl)C([H])=C([H])C([H])=C1Cl
[H]N([H])S(=O)(=O)C1=C([H])C(=C([H])C([H])=C1Cl)C(=O)C([H])([H])SC1=NC2=C(N1[H])C([H])=C([H])C(Br)=C2[H]
[H]N(C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[C@]1([H])OC2=C(C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N(C(=O)N1C([H])([H])C([H])([H])C2(C3=C(C([H])=C([H])C([H])=C3[H])N(C2([H])[H])S(=O)(=O)C([H])([H])[H])C([H])([H])C1([H])[H])C1=NC(=C([H])C([H])=N1)C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N1C([H])([H])C([H])([H])[C@@]([H])(OC2=C([H])C([H])=C([H])C3=C([H])C([H])=C(N=C23)C2=NN=C3C([H])=C([H])C([H])=C([H])N23)C1([H])[H]
[H]OC1=C(N([H])S(=O)(=O)C([H])([H])[H])C([H])=C(C([H])=C1[H])C([H])([H])[C@]([H])(O[H])C([H])([H])N([H])[C@@]([H])(C1=C([H])C([H])=C(OC([H])([H])[H])C(OC([H])([H])[H])=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C(Cl)=C1[H]
[H]N=C(N([H])[H])N([H])C([H])([H])C([H])([H])C([H])([H])[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)C1=C([H])N=C([H])C(Br)=C1[H])C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C(=O)N([H])[C@]([H])(C(=O)N([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]O[C@@]([H])(C([H])([H])N(C1=C([H])C(OC([H])([H])C2=C([H])C(OC(F)(F)F)=C([H])C([H])=C2[H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C(OC(F)(F)C([H])(F)F)=C1[H])C(F)(F)F
[H]N(C(=O)C([H])([H])S(=O)(=O)N([H])C1=C(C([H])=C([H])C([H])=C1C([H])(C([H])([H])[H])C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]OC(=O)C1=C(N(C(=C1C1=C([H])C(=C([H])C([H])=C1[H])N1C([H])([H])C([H])([H])N(C2=C([H])C([H])=C(N([H])S(=O)(=O)C3=C([H])C([H])=C(N([H])[C@@]([H])(C([H])([H])SC4=C([H])C([H])=C([H])C([H])=C4[H])C([H])([H])C([H])([H])N4C([H])([H])C([H])([H])C([H])(O[H])C([H])([H])C4([H])[H])C(=C3[H])S(=O)(=O)C(F)(F)F)C([H])=C2[H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C(Cl)C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)N([H])C1=C([H])C([H])=C([H])C([H])=C1OC1=C([H])C([H])=NN1C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C(OC(F)(F)F)C([H])=C1[H]
[H]N([H])[C@]1([H])C([H])([H])[C@]([H])(C2=C([H])C([H])=NC([H])=C2C([H])([H])C(=O)C2=C([H])C([H])=C(F)C(=N2)C2=C(F)C([H])=C(OC([H])([H])[H])C([H])=C2F)C([H])([H])C(C([H])([H])[H])(C([H])([H])[H])C1([H])[H]
[H]N1N=C(C2=C([H])C([H])=C([H])C([H])=C2C1=O)C([H])([H])C1=C([H])C([H])=C([H])C(=C1[H])N1C(=O)C([H])([H])C([H])([H])C1([H])[H]
[H]N=C([H])C(\[H])=N\C1=C([H])C([H])=C(C([H])=C1[H])C(=O)N([H])C1=C(N([H])[H])C([H])=C([H])C(=C1[H])C1=C([H])C([H])=C([H])S1
[H]OC1=C([H])C(=C([H])C([H])=C1[H])[C@]1([H])N(C(=O)C([H])([H])C([H])([H])N([H])[H])C([H])([H])C([H])([H])C2=C1N([H])C1=C2C([H])=C(OC(F)(F)F)C([H])=C1[H]
[H]N(C1=NC([H])=C(O1)C1=C([H])C([H])=C([H])C([H])=C1N(C(=O)C([H])([H])N([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C1=C([H])C(OC([H])([H])[H])=C(C([H])=C1[H])C1=C([H])N=C([H])O1
[H]N(C(=O)[C@@]([H])(N([H])C(=O)C([H])([H])C1=C([H])N=C([H])N1[H])C([H])([H])OC([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C(OC2=C([H])C([H])=C(F)C([H])=C2[H])C([H])=C1[H]
[H]OC(=O)C([H])([H])[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@]1([H])N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])[H])C([H])([H])SSC1([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(O[H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])N([H])C([H])=N1)C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)O[H])C([H])([H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H])[C@@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])[H])[C@@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])[H]
[H]N=C(N([H])C(=O)N1C([H])([H])C([H])([H])N(C2=C(OC([H])([H])[H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H])N([H])C([H])([H])C1=C2C([H])=C([H])C([H])=C([H])C2=C([H])C([H])=C1[H]
[H]N(C([H])([H])C([H])([H])OC1=C2C([H])=C([H])N([H])C2=C([H])C([H])=C1[H])[C@@]1([H])C([H])([H])C([H])([H])[C@]([H])(C2=C([H])N([H])C3=C([H])C([H])=C(F)C([H])=C23)C([H])([H])C1([H])[H]
[H]C1=C([H])C([H])=C(OC([H])([H])[C@@]2([H])N(C([H])([H])C2([H])[H])S(=O)(=O)C2=C([H])C([H])=C3N(C(=O)C(=O)C3=C2[H])C([H])([H])C2=C([H])N=C(F)C([H])=C2[H])C([H])=C1[H]
CN(CCCCCCCCCCCN)CCCCCCCCCCCNC(=O)C1=NN(C(=C1C)C1=CC=C(Cl)C=C1)C1=C(Cl)C=C(Cl)C=C1
[H]O\N=C(\C(=O)N([H])C([H])([H])C([H])([H])SSC([H])([H])C([H])([H])N([H])C(=O)C(=N\O[H])\C([H])([H])C1=C([H])C([H])=C(O[H])C(Br)=C1[H])C([H])([H])C1=C([H])C([H])=C(O[H])C(Br)=C1[H]
[H]N([C@]1([H])C(=O)N(C([H])([H])C2=C([H])C3=C(N2[H])C([H])=NC([H])=C3[H])C([H])([H])C1([H])[H])S(=O)(=O)C1=C([H])C2=C(S1)C([H])=C([H])C([H])=N2
[H]N(C1=C([H])C([H])=[N+](C2=C([H])C([H])=C([H])C([H])=C2[H])C2=C1C([H])=C(OC([H])([H])[H])C([H])=C2C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]N([H])C(=NC([H])([H])C([H])([H])N([H])C(=O)[C@]1([H])N(C(=O)[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)C([H])([H])[H])C([H])([H])C2=C([H])N([H])C([H])=N2)C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])[C@]([H])(OC([H])([H])C2=C([H])C3=C([H])C([H])=C([H])C([H])=C3C([H])=C2[H])C1([H])[H])N([H])[H]
[H]N([H])C1=C([H])C(OC([H])([H])[H])=C(C([H])=C1Cl)C(=O)N([H])[C@@]1([H])C([H])([H])[C@]2([H])N(C([H])([H])C3=C([H])C([H])=C(F)C([H])=C3[H])[C@@]1([H])C([H])([H])C([H])([H])C2([H])[H]
[H]N(C1=NC([H])=C([H])C(=N1)N(C1=C(C([H])=C([H])C([H])=C1[H])C([H])([H])[H])C([H])([H])[H])C1=C([H])C(=C([H])C(=C1[H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]O[C@]([H])(C([H])([H])[H])[C@]([H])(N([H])[H])C(=O)N1C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])C([H])([H])C(=O)N([H])[H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=N[H])N([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])[H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=N[H])N([H])[H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=N[H])N([H])[H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=N[H])N([H])[H])C([H])([H])C(=O)N([H])[H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=N[H])N([H])[H]
[H]N(C#N)C(=N/C([H])([H])C1=C([H])C([H])=C([H])C(=C1[H])C([H])([H])[H])\N([H])C1=C([H])C([H])=C(C2=C([H])N=C([H])O2)C(OC([H])([H])[H])=C1[H]
[H]OC(=O)C([H])([H])C([H])([H])C1=C([H])C([H])=C(OC(F)(F)F)C(=C1[H])C1=C([H])C2=C(C([H])=C1C([H])([H])[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C(=O)N2C([H])([H])C(F)(F)F
[H]C1=C([H])C(=C([H])C(=C1[H])C1=NOC(=N1)[C@]1([H])N(C(=O)C2([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])[H]
[H]N([H])C1=NC(=C([H])C([H])=N1)C1=C([H])N([H])C2=C([H])C(=C([H])C([H])=C12)[N+]([O-])=O
[H]N(C(=O)C1=C([H])N(C(=C([H])C1=O)C1=C([H])C([H])=C(Cl)C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C1=C([H])C(=C([H])C([H])=C1[H])C(F)(F)F
[H]N([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C(=NN1C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])C(F)(F)F
[H]N1C(=NC2=C1C1=C([H])C([H])=C([H])C([H])=C1C([H])=C2C([H])(C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
ClC1=CC=C(C(Cl)=C1)S(=O)(=O)NC1=CC(Cl)=C(OC2=CC(=CN=C2)C#N)C(Cl)=C1
[H]N1C(=O)N([H])C(=O)C(N2C([H])([H])C([H])([H])N(C(=O)C3=NN(C4=C3C([H])=C([H])C([H])=C4[H])C([H])([H])[H])C([H])([H])C([H])([H])C2([H])[H])(C1=O)C1=C([H])C([H])=C(OC2=C([H])C([H])=C([H])C([H])=C2[H])C([H])=C1[H]
[H]OC1=C([H])C(=C([H])C([H])=C1[H])[C@]1([H])OC2=C([H])C([H])=C([H])C(OC([H])([H])[H])=C2C2=C1C([H])=C(N([H])S(=O)(=O)C([H])([H])[H])C([H])=C2[H]
[H]N1C2=NN(C([H])=C2C(=NC2=C1C([H])=C([H])C(Br)=C2[H])N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H])C([H])([H])[H]
[H]N(C(=O)C([H])([H])OC1=C([H])C(=NC(=C1[H])C([H])([H])[H])C([H])([H])[H])C1=C([H])C(=NC(=N1)C1=C([H])C([H])=C(O1)C([H])([H])[H])N1N=C(C([H])=C1C([H])([H])[H])C([H])([H])[H]
[H]C([H])=C([H])C(=O)N([H])C1=C(OC([H])([H])C([H])([H])C([H])([H])N2C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])C([H])=C2N=C([H])N=C(N([H])C3=C([H])C(Br)=C(F)C([H])=C3[H])C2=C1[H]
[H]OC(=O)C([H])([H])OC1=C([H])C([H])=C([H])C(=C1[H])C([H])([H])N1C2=C([H])C(OC(F)(F)F)=C([H])C([H])=C2C(C(=O)C2=C([H])C([H])=C(Cl)C([H])=C2[H])=C1C([H])([H])[H]
[H]N(C1=NC(=NC(=C1[H])C1=NC([H])=C([H])N=C1[H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C1=C([H])C2=C([H])C([H])=C([H])C([H])=C2N=C1[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])OC1=C([H])C(=C([H])C([H])=C1OC([H])([H])[H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]OC1=C([H])C([H])=C(C([H])=C1[H])C1=C(O[C@]2([H])O[C@]([H])(C([H])([H])O[H])[C@@]([H])(O[H])[C@]([H])(O[H])[C@@]2([H])O[H])C(=O)C2=C(O1)C([H])=C(O[H])C([H])=C2O[H]
[H]C1=C([H])N=C(O1)C(=O)C([H])([H])C([H])([H])C([H])([H])C1([H])C([H])([H])C([H])([H])N(C(=O)OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N(C(=O)[C@@]1([H])C([H])([H])C([H])([H])[C@@]2(OC(=O)C3=C([H])N=C([H])C([H])=C23)C([H])([H])C1([H])[H])C1=NC([H])=C(C([H])=N1)C1=C([H])C([H])=C([H])C(F)=C1[H]
[H]N(C(=O)C([H])([H])C([H])([H])C1=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C([H])=C1[H])[C@]([H])(C(=O)C([H])([H])Cl)C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]\C(=C(/[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C(=O)C([H])([H])Br
[H]OC(=O)[C@]12C([H])([H])C([H])([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[C@@]1([H])C1=C([H])C([H])([H])[C@]3([H])[C@@]4(C([H])([H])[H])C([H])([H])[C@@]([H])(O[H])[C@]([H])(O[H])C(C([H])([H])[H])(C([H])([H])[H])[C@]4([H])C([H])([H])C([H])([H])[C@@]3(C([H])([H])[H])[C@]1(C([H])([H])[H])C([H])([H])C2([H])[H]
[H]OC1(C([H])([H])C([H])([H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])[C@@]([H])(C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])N(C([H])([H])[H])S(=O)(=O)C2=C([H])C([H])=C([H])S2)C([H])([H])C1([H])[H]
[H]N(C(=O)N(C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(S1)C1=C2C(=NN1[H])C1=C(C([H])=C(C([H])=C1[H])C([H])([H])N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H])C2([H])[H])C1=C([H])C(F)=C([H])C(=C1[H])C(F)(F)F
[H]C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C2=NC3=C(N2C([H])=C1[H])C(=O)N(C(=O)N3C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])[H]
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[H]C1=C([H])C([H])=C(F)C(=N1)C1=C([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N([H])[C@@]([H])(C([H])([H])[H])C([H])([H])N1C([H])=C([H])C2=C([H])C([H])=C(F)C([H])=C12
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[H]OC(=O)C1=C([H])C([H])=C(N([H])C(=O)C([H])([H])C([H])([H])N2C(=O)S\C(=C(\[H])C3=C([H])C([H])=C(Cl)C([H])=C3[H])C2=O)C([H])=C1[H]
[H]N(C(=O)C1=C([H])C(=O)N(C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C(Cl)C([H])=C1[H])C([H])([H])C1=C([H])N(C2=C([H])C([H])=C([H])C([H])=C2[H])C2=C([H])C(Cl)=C([H])C([H])=C2C1=O
[H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])[N+](C([H])([H])[H])(C([H])([H])[H])[C@@]([H])(C([H])([H])[H])C([H])([H])[C@]1([H])C([H])=C([H])C([H])=C([H])C1([H])[H]
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[H]OC(=O)C1=C(C([H])=C2C([H])=C(C([H])=C([H])C2=N1)C1=C([H])C([H])=C(OC([H])([H])C2=C(ON=C2C2=C(Cl)C([H])=C([H])C([H])=C2Cl)C([H])(C([H])([H])[H])C([H])([H])[H])C([H])=C1[H])C([H])([H])[H]
[H]N([H])[C@]1([H])C2=C([H])C([H])=C([H])C([H])=C2[C@]([H])(C2=C([H])C([H])=C(Cl)C(Cl)=C2[H])C([H])([H])C1([H])[H]
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[H]OC(=O)C1=C(O[H])C([H])=C2C3=C(C4=C(N3[H])C([H])=C(C([H])=C4[H])C3=C([H])C(OC([H])([H])C([H])([H])C([H])([H])[H])=C([H])C([H])=C3[H])C([H])([H])C([H])([H])C2=C1[H]
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[H]OC1=C([H])C([H])=C(C([H])=C1[H])[C@@]1([H])C([H])([H])C([H])([H])[C@]([H])(N2C([H])([H])C([H])(N([H])C(=O)C([H])([H])N([H])C(=O)C3=C([H])C([H])=C([H])C(=C3[H])C(F)(F)F)C2([H])[H])C([H])([H])C1([H])[H]
[H]OC(=O)[C@@]1([H])N(C(=O)N2C([H])([H])C([H])([H])N(C(=O)C([H])([H])C3=C([H])C([H])=C(OC4=C([H])C([H])=C([H])C([H])=C4[H])C([H])=C3[H])C([H])([H])C2([H])[H])C(=O)[C@]1([H])C([H])([H])C1([H])C([H])([H])C([H])([H])N([H])C([H])([H])C1([H])[H]
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[H]\C(=C(\[H])C1=C([H])C(=C([H])C([H])=C1[H])N(C(=O)C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C(=C([H])C([H])=C1[H])C([H])([H])[H])C(=O)OC([H])([H])[H]
[H]N(OC([H])([H])[H])C(=O)C1=C([H])C([H])=C(C(N([H])C2=NC([H])=NN3C([H])=C(N([H])C(=O)OC([H])([H])[H])C(=C23)C([H])([H])[H])=C1[H])C([H])([H])[H]
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[H]O[C@@]([H])(C([H])([H])[C@]([H])(C(=O)N([H])C([H])([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])[C@@]([H])(N([H])C(=O)C1=NC2=C([H])C([H])=C([H])C([H])=C2N=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N1C(=O)C2=C(C1=O)C1=C(C([H])=C([H])C3=C1N(C([H])=C3[H])C([H])([H])[H])C1=C2C2=C(N1[H])C(=C([H])C([H])=C2[H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])SC([H])([H])C1([H])[H]
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[H]N(C(=O)C1=C([H])C([H])=C(Br)O1)C1=C([H])C([H])=C([H])C([H])=C1N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
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[H]N(C(=O)C(\[H])=C(/[H])C1=C([H])N(C2=C([H])C([H])=C([H])C(OC3=C(F)C([H])=C(F)C([H])=C3[H])=C12)C([H])([H])[H])S(=O)(=O)C1=C(F)C([H])=C(F)C(F)=C1[H]
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[H]N([H])S(=O)(=O)C1=C([H])C([H])=C(C([H])=C1[H])N1N=C(C2=C1C1=C([H])C([H])=C([H])C([H])=C1C([H])([H])S2)C(F)(F)F
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[H]OC1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])N([H])C(=O)C1=C([H])C2=C([H])C([H])=C(OC([H])([H])[H])C(OC([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])=C2N=C1O[H]
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[H]N([H])S(=O)(=O)C1=C([H])C2=C(S1)S(=O)(=O)C([H])([H])C(=O)N2[H]
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[H]OC([H])([H])C([H])([H])C1(C(=O)N([H])C(=O)N([H])C1=O)C1=C([H])C([H])=C(OC2=C([H])C([H])=C([H])C([H])=C2[H])C([H])=C1[H]
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[H]C1=C([H])C2=C(C([H])=C1[H])C([H])([H])C([H])([H])C1=C(C([H])=C(Br)C([H])=C1[H])C([H])([H])N2C(=O)C([H])([H])[H]
[H]OC(=O)C1=C(Cl)C(=C2C(=C1Cl)C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C([H])([H])N1C([H])=NC2=C1N([H])C([H])=NC([H])([H])[C@@]2([H])O[H]
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[H]\C(=N/N(C([H])([H])[H])S(=O)(=O)C1=C(C([H])=C([H])C(=C1[H])[N+]([O-])=O)C([H])([H])[H])C1=C2C([H])=C(Cl)C([H])=C([H])N2N=C1[H]
[H]N1[C@@]2([H])C(C(=O)N(C([H])([H])C3=C(Cl)C(Cl)=C([H])C([H])=C3[H])C3([H])C([H])([H])C3([H])[H])=C(C3=C([H])C([H])=C(OC([H])([H])C([H])([H])OC4=C(Cl)C([H])=C(F)C([H])=C4Cl)C([H])=C3[H])C([H])([H])[C@]1([H])C([H])([H])N(C(=O)C([H])([H])[H])C2([H])[H]
[H]C1=C([H])C(C2=C3N=C(C([H])=C(N3N=C2C([H])([H])[H])N2C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])[H])=C(Cl)C([H])=C1Cl
[H]N(C(=O)N([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC(OC([H])([H])[H])=NC(=N1)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C(=O)N([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(C(=O)OC([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)C([H])([H])SC([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]O[C@]1([H])C([H])([H])N(C(=O)C2=C([H])C([H])=C([H])S2)C([H])([H])C([H])([H])[C@@]1([H])N1C([H])([H])C([H])([H])C([H])(C(=O)C2=C([H])C([H])=C(F)C([H])=C2[H])C([H])([H])C1([H])[H]
[H]O\N=C(\C1=C([H])C([H])=C([H])C(=C1[H])C(N([H])C(=O)N([H])C1=C([H])C([H])=C(Cl)C(=C1[H])C(=O)N([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C(C([H])=C1C1=C([H])C([H])=C([H])C([H])=C1C([H])([H])[H])C([H])([H])OC([H])([H])C1=C([H])C([H])=C(O1)C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])[C@]([H])(C([O-])=O)C([H])([H])C([H])([H])SC([H])([H])[H]
[H]OC(=O)C([H])([H])C([H])([H])[C@]([H])(N([H])C(=O)C1=C([H])C([H])=C(C([H])=C1[H])N(C([H])([H])C#C[H])C([H])([H])C1=C([H])C2=C(Cl)C([H])=C(N=C2C([H])=C1[H])C(=O)N([H])[H])C(=O)O[H]
[H]N([H])C(=N\N=C(/[H])C1=C([H])C([H])=C([H])C([H])=C1[H])N([H])[H]
[H]N(C(=O)C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])[C@]1([H])C2=C(OC([H])([H])[H])C([H])=C([H])C3=C([H])C([H])=C([H])C(=C23)C1([H])[H]
[H]OC1=C2C(=NC3=C1C([H])=C([H])C([H])=C3[H])N(N=C2C([H])([H])[H])C1=C([H])C([H])=C([H])C(=C1[H])[N+]([O-])=O
[H]N(C1=C([H])C([H])=C(Br)C([H])=C1F)C1=C(F)C(=O)N(C([H])=C1C(=O)N([H])C([H])([H])C1([H])C([H])([H])C1([H])[H])C([H])([H])[H]
[H]ON([H])C(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])OC1=C([H])C([H])=C(C([H])=C1[H])N(C([H])([H])[H])C([H])([H])[H]
[H]OC1=C(N([H])C2=NSN=C2N([H])[C@@]([H])(C2=C([H])C([H])=C3OC([H])([H])OC3=C2[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])=C([H])C([H])=C1C(=O)N(C([H])([H])[H])C([H])([H])[H]
[H]N(\N=C(/[H])C1=C([H])C([H])=C(C([H])=C1[H])[N+]([O-])=O)C(=O)C([H])([H])N([H])C(=O)C(\[H])=C(/[H])C1=C([H])C([H])=C([H])O1
[H]N(C1=NN=C(C([H])=C1C([H])(C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N(C(=O)C([H])([H])OC1=C([H])C([H])=C(F)C([H])=C1[H])C1=C([H])C(=NC(=N1)C1=C([H])C([H])=C(O1)C([H])([H])[H])C1=NC([H])=C([H])S1
[H]OC1(C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C#CC2=C([H])N([H])C([H])=N2)C([H])([H])C1([H])[H]
[H]OC(=O)C(\[H])=C(/[H])C1=C([H])C(=C(O[H])C(=C1[H])C([H])([H])C([H])=C(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])=C(C([H])([H])[H])C([H])([H])[H]
[H]OC([H])([H])[C@]1([H])N([H])C([H])([H])C2=C([H])C(=C([H])C([H])=C2C1([H])[H])S(=O)(=O)N([H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]N(C(=O)C1=C([H])N(C(=N1)C1=C([H])C([H])=C(Cl)C([H])=C1Cl)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]OC(=O)C([H])([H])C([H])([H])[C@]([H])(N([H])C(=O)C1=C([H])C([H])=C(C([H])=C1[H])N(C([H])([H])[H])C([H])([H])C1=NC2=C(N=C(N=C2O[H])N([H])[H])C([H])=C1[H])C(=O)O[H]
[H]N(C(=O)[C@@]([H])(N([H])C(=O)C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C(=O)N([H])S(=O)(=O)C1=C([H])C([H])=C(N([H])C([H])([H])C([H])([H])SC2=C([H])C([H])=C([H])C([H])=C2[H])C(=C1[H])[N+]([O-])=O
[H]N([H])S(=O)(=O)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])N([H])C(=O)C([H])([H])[N+]1=C(C([H])=C(C([H])=C1C([H])(C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]\C(=C(\[H])C1=C([H])C(=C([H])C([H])=C1[H])N(C(=O)C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C(\C([H])=C(/[H])C2=C([H])C([H])=C(OC([H])([H])[H])C([H])=C2[H])C([H])=C1[H])C(=O)OC([H])([H])[H]
[H]N(C(=O)N1C([H])([H])C([H])([H])N(C2=NC(=C(C([H])=C2C#N)C(=O)OC([H])([H])C([H])([H])[H])C(F)(F)F)C([H])([H])C1([H])[H])C1=C([H])C([H])=C([H])C(=C1[H])C([H])([H])[H]
[H]N1C([H])([H])C([H])([H])C2(OC3=C(C([H])=C([H])C([H])=C3[H])C(=C2[H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N(C1=C(Br)C(=O)N(N=C1[H])C1=C(Cl)C([H])=C([H])C([H])=C1Cl)C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C1=NC([H])=NC2=C1C([H])=NC(N([H])C([H])([H])C([H])([H])C1=C([H])N([H])C([H])=N1)=C2[H])C1=C([H])C([H])=C([H])C(Br)=C1[H]
COC(=O)C(C)(C)COC1=C(C=C(C=C1)C1=NC(N)=NC(O)=C1)C#N
[H]N(C1=NN(C2=C1C([H])=NC(=N2)N([H])C1=C([H])C([H])=C(C([H])=C1[H])N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H])C([H])([H])C([H])([H])C(OC([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C1=C(C([H])=C([H])C([H])=C1C([H])([H])[H])C([H])([H])[H]
[H]OC(=O)C([H])([H])[C@]1([H])N([H])C(=O)[C@@]2([H])N(C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]3([H])N([H])C(=O)[C@@]4([H])N(C(=O)[C@@]5([H])N(C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)C([H])([H])N([H])[H])C([H])([H])SSC3([H])[H])C([H])([H])SSC([H])([H])[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])C1=O)C([H])([H])C1=C([H])C([H])=C(O[H])C([H])=C1[H])C(=O)O[H])C([H])([H])O[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C5([H])[H])C([H])([H])C([H])([H])C4([H])[H])C([H])([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C(=O)N([H])[H])C([H])([H])C(=O)N([H])[H])C([H])([H])C([H])([H])C2([H])[H]
[H]C1=C([H])N(C(=N1)C([H])([H])[H])C([H])([H])C1([H])C([H])([H])C([H])([H])N(C(=O)C([H])([H])C([H])([H])S(=O)(=O)C2=C([H])C3=C([H])C([H])=C(Cl)C([H])=C3C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N([H])C1=NC([H])=NC2=C1C([H])=C([H])C(=C2[H])N1N=C(C2=C1C([H])([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C2=O)C([H])([H])[H]
[H]O[C@]([H])(C1=C([H])C([H])=C([H])C(Cl)=C1[H])C([H])([H])N([H])C1=C(C2=NC3=C(C([H])=C(C([H])=C3N2[H])C(=O)N(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C(=O)N([H])C([H])=C1[H]
[H]N1N(C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])[C@](C1=O)(C([H])([H])[H])C([H])([H])OC([H])([H])[H]
[H]OC(=O)C([H])([H])N1C2=C(C([H])=C(I)C([H])=C2[H])C2=C1C(=S)N(C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C2([H])[H]
[H]C([H])=C([H])C([H])([H])N([H])C(=O)C([H])([H])N1C(=O)N(C2=C1C([H])=C([H])C([H])=C2[H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])[C@@]([H])(OC2=C([H])C(OC([H])([H])[H])=C([H])C([H])=C2C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N1C2=C([H])C([H])=C([H])C([H])=C2N=C1[C@@]1([H])C([H])([H])N(C(=O)C1([H])[H])C1=C([H])C([H])=C([H])C(=C1[H])C(F)(F)F
[H]OC1=C([H])C([H])=C(C([H])=C1[H])[C@@]1([H])OC2=C(C(O[H])=C([H])C(O[H])=C2[H])C(=O)C1([H])[H]
[H]C1=C([H])C(OC(=O)C2=C([H])C3=C([H])C(=C([H])C([H])=C3OC2=O)C([H])([H])Cl)=NC(Cl)=C1[H]
[H]N([H])C1=C2C([H])=C(C(=NC2=NC([H])=N1)C1=C([H])SC([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H]
[H]C1=C(SC2=C1C([H])=C(OC([H])([H])[H])C(OC([H])([H])[H])=C2[H])C(=O)[C@]1([H])C([H])([H])C([H])([H])C([H])([H])[N@@+](C([H])([H])[H])(C([H])([H])C#N)C([H])([H])C1([H])[H]
[H]N1C(=O)N(C([H])([H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C([H])([H])C2=C([H])N(C3=C([H])C(Cl)=C([H])C([H])=C23)C2=C([H])C([H])=C(F)C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N(C(=O)C([H])([H])[H])[C@@]1([H])C([H])([H])C([H])([H])[C@]([H])(C([H])([H])C([H])([H])N2C([H])([H])C([H])([H])N(C3=C([H])C([H])=C([H])C(=C3[H])C(F)(F)F)C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]C1=C(N2N=C(OC([H])([H])[H])C(N(C3=C([H])N=C([H])C([H])=C3[H])C([H])([H])C([H])([H])C([H])([H])[H])=C2S1)C1=C(OC([H])([H])[H])C([H])=C(C([H])=C1OC([H])([H])[H])C([H])([H])OC([H])([H])[H]
[H]N(C1=NC(N([H])[C@]2([H])C([H])([H])C([H])([H])C([H])([H])[C@@]2([H])N(C([H])([H])[H])C([H])([H])[H])=C(C([H])=N1)C(F)(F)F)C1=C([H])C([H])=C(C([H])=C1[H])C(=O)N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C(C([H])=C1C([H])([H])[H])C([H])([H])[H])[C@]([H])(C(=O)OC([H])([H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])[N+]([O-])=O
[H]N(C(=O)OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C(F)(F)C(=O)[C@@]([H])(N([H])C(=O)[C@@]1([H])N(C(=O)[C@@]([H])(N([H])C(=O)OC2=C([H])C([H])=C([H])C([H])=C2[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C1([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])[C@@]1([H])C([H])([H])C([H])([H])[C@@]([H])(N([H])C([H])([H])C(=O)N2C([H])([H])C([H])([H])C([H])([H])[C@@]2([H])C#N)C([H])([H])C1([H])[H]
[H]N([H])C([H])([H])C(=O)N([H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)N([H])[H]
[H]N([H])C1=C([H])C([H])=C(N([H])C2=NC([H])=NC3=C2N=NN3C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])=C1[H]
[H]C1=NC(=C(S1)C([H])([H])C([H])([H])N1C([H])=C(C(=O)C2([H])C(C([H])([H])[H])(C([H])([H])[H])C2(C([H])([H])[H])C([H])([H])[H])C2=C1C([H])=C([H])C([H])=C2[H])C([H])([H])[H]
[H]N([H])S(=O)(=O)C1=C([H])C(=C(N([H])S(=O)(=O)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F)C([H])=C1Cl)S(=O)(=O)N([H])[H]
[H]C1=C(OC([H])([H])[H])C(OC([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])=C(OC([H])([H])[H])C([H])=C1C(=O)OC([H])([H])C([H])([H])[N+](C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]N1C([H])([H])C([H])([H])C2=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C3=C2[C@@]1([H])C([H])([H])C1=C(C([H])=C([H])C([H])=C1[H])C3([H])[H]
[H]N(C(=O)OC1=C2C(=C([H])C([H])=C1[H])[C@@]1([H])N(C([H])([H])[H])C([H])([H])C([H])([H])[C@@]1([H])C([H])([H])C2([H])[H])C([H])([H])[H]
ClC1=C(CN2C=NC(=O)C3=C2N=C(S3)N2CCOCC2)C=CS1
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[H]OP(=O)(O[H])C1=C([H])C([H])=C(N([H])C(=O)C2=C([H])C([H])=C(C([H])=C2[H])N2C([H])=C(C3=C(N=C([H])N=C23)N([H])[H])C2=C([H])C(OC([H])([H])[H])=C([H])C([H])=C2[H])C([H])=C1P(=O)(O[H])O[H]
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[H]OC([H])([H])[C@@]1([H])O[C@@]([H])(N2C([H])=NC3=C2N=C(N=C3N([H])[H])N([H])\N=C(\[H])C2([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])[C@]([H])(O[H])[C@]1([H])O[H]
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[H]N([H])S(=O)(=O)OC1=C([H])C([H])=C(C([H])=C1Cl)C1=C([H])C([H])=C([H])C(=C1[H])C([H])([H])N1N=C([H])N=C1[H]
[H]N([H])C1=NC(N(C(=N1)N([H])[H])C1=C([H])C(OC([H])([H])C([H])([H])OC2=C([H])C([H])=C([H])C(=C2[H])C(F)(F)F)=C([H])C([H])=C1[H])(C([H])([H])[H])C([H])([H])[H]
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[H]C1=NC(OC2=C([H])C([H])=C(OC(=O)N3C([H])([H])C([H])([H])C([H])([H])C3([H])[H])C([H])=C2[H])=C([H])C([H])=C1C(F)(F)F
[H]N(C(=O)N([H])C1=C([H])C([H])=C([H])C([H])=C1C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C(=O)N([H])[C@]([H])(C([H])([H])C(=O)N([H])[C@@]([H])(C([O-])=O)C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]OC([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])OC(=O)N([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]N([H])C(=O)C1=C([H])C([H])=C(F)C([H])=C1OC([H])([H])C1=C([H])C([H])=C(F)C(=C1[H])C(=O)N1C([H])([H])C([H])([H])N([H])C([H])([H])C1([H])[H]
[H]N(C1=NC2=C(C([H])=N1)C([H])=C(C(=O)N2C([H])([H])[H])C1=C(Cl)C([H])=C([H])C([H])=C1Cl)C([H])([H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H]
[H]C1=C([H])C([H])=C2C(C([H])=C([H])C([H])=C2C(=O)C2=C([H])C([H])=C(OC([H])([H])C([H])([H])N3C([H])([H])C([H])([H])OC([H])([H])C3([H])[H])C3=C([H])C([H])=C([H])C([H])=C23)=C1[H]
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[H]N1C(=NC(=C1C1=C([H])C([H])=C(F)C([H])=C1[H])C1=C([H])C([H])=NC([H])=C1[H])C1=C([H])C(Br)=C([H])C([H])=C1[H]
[H]N([H])[C@]1([H])C([H])([H])N(C2=C(C#N)C3=C(N2C([H])([H])C#CC([H])([H])[H])C(=O)N(C([H])=N3)C([H])([H])C2=NC([H])=C([H])C3=C([H])C([H])=C([H])C([H])=C23)C([H])([H])C([H])([H])C1([H])[H]
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[H]N([H])[C@](C1=C([H])N=C([H])N1C([H])([H])[H])(C1=C([H])C([H])=C(Cl)C([H])=C1[H])C1=C([H])C2=C3N(C(=O)C([H])=C(C4=C([H])C(Cl)=C([H])C([H])=C4[H])C3=C1[H])C([H])([H])C([H])([H])C2([H])[H]
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[H]N1C(=O)C(C2=C([H])C(=NO2)C([H])([H])[H])=C(C2=C([H])C(=C([H])C([H])=C2[H])C([H])([H])[H])C2=C([H])C(Cl)=C([H])C([H])=C12
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[H]OC([H])([H])C([H])([H])N([H])C(=O)N([H])C1=NC2=C([H])C(=C([H])C([H])=C2N1[H])C(=O)C1=C([H])C([H])=C([H])C([H])=C1[H]
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[H][C@@]1(CCCCN1CCCC1=CC=CC=C1)[C@H](C(=O)OC)C1=CC=CC=C1
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OCC[C@]1(CCCNC1)C1=CC(Cl)=C(Cl)C=C1
[H]OC(=O)C([H])([H])[C@]1([H])N([H])C(=O)C([H])([H])N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])[H])C([H])([H])C([H])([H])C([H])([H])\N=C(N([H])[H])/N([H])C(=O)[C@]([H])(N([H])[H])[C@]2(SSC([H])([H])[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C1=O)C([H])([H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])N=C(N([H])[H])N([H])[H])C(=O)N([H])[C@]([H])(C(=O)O[H])C([H])([H])C([H])([H])C([H])([H])N=C(N([H])[H])N([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C(=O)N([H])[H])C([H])([H])C1=C([H])N([H])C([H])=N1)C([H])([H])C([H])([H])C([H])([H])N=C(N([H])[H])N([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C1=NC2=C(N=N1)C(=O)C1=C2C([H])=C([H])C([H])=C1[H]
[H]OC(=O)[C@@]([H])(N([H])C(=O)C([H])([H])N([H])C(=O)C([H])([H])N([H])C(=O)C([H])([H])N([H])C(=O)C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)N([H])[H])C([H])([H])C(=O)N([H])[H]
[H]O\N=C1/C(=O)N(C2=C([H])C([H])=C(F)C([H])=C12)C([H])([H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]OC(=O)[C@]1([H])C2=C([H])C([H])=C([H])C([H])=C2C(=O)N(C([H])([H])C2=C([H])C([H])=C(Cl)C([H])=C2[H])[C@@]1([H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]N(\N=C(\[H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H])C1=NC(=C([H])S1)C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]N(C1=NC(=O)C2(O1)C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]C1=C([H])C(=C([H])C([H])=C1OC([H])([H])[H])[C@]1([H])C2=C([H])C([H])=C(OC([H])([H])C([H])([H])C([H])([H])N3C([H])([H])C([H])([H])N(C([H])([H])C3([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])=C2C([H])([H])N(C([H])([H])[H])C1([H])[H]
[H]N1N=NC(=N1)C1=C([H])C([H])=C(OC([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])OC2=C([H])C([H])=C3N(C([H])=C([H])C3=C2C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])=C1[H]
[H]OC(=O)C([H])([H])[C@@]1([H])N([H])C(=O)N([H])N([H])C(=O)[C@]([H])(N([H])C(=O)[C@]([H])(N([H])C(=O)[C@]([H])(N([H])C1=O)C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])N=C(N([H])[H])N([H])[H]
[H]OP(=O)(O[H])OC([H])([H])[C@@]12C([H])([H])[C@]1([H])[C@@]([H])(N1C([H])=NC3=C1N=C(N=C3N([H])C([H])([H])[H])C#C[H])C([H])([H])[C@]2([H])OP(=O)(O[H])O[H]
[H]C1=C([H])C([H])=C([H])C(=N1)N(C(=O)[C@]12C([H])([H])C([H])([H])[C@](I)(C([H])([H])C1([H])[H])C([H])([H])C2([H])[H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C(OC([H])([H])[H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]C1=NC(=C([H])N1C([H])([H])[H])C(=O)N(C([H])([H])C1=C([H])C(OC(F)(F)F)=C([H])C([H])=C1[H])C([H])([H])[C@@]1([H])[C@]2([H])C([H])([H])N(C([H])([H])C3([H])C([H])([H])C([H])([H])C([H])([H])C3([H])[H])C([H])([H])[C@]12[H]
[H]C([H])=C([H])C([H])([H])OC1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N(C1=C([H])C([H])=C([H])C(N([H])S(=O)(=O)C([H])([H])[H])=C1C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C1=C([H])C2=C(C([H])=C1[H])[N+](=C([H])C([H])=C2[H])C([H])([H])C1=C([H])C(OP([O-])(=O)OC2=C(OC([H])([H])[H])C(OC([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])=C([H])C([H])=C2[H])=C([H])C([H])=C1[H]
[H]N(C(=O)N([H])C1=C([H])C(=C(Br)C([H])=C1[H])C(F)(F)F)C1=C([H])C([H])=C(OC2=C([H])C([H])=NC(=C2[H])C(=O)N([H])C([H])([H])C([H])([H])N2C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])C([H])=C1[H]
[H]O[C@]([H])(C#CC([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C1=C(C([H])=C([H])S1)C1=C([H])C(=C(OC2=C([H])C([H])=C(OC([H])([H])C([H])([H])[H])C([H])=C2[H])C([H])=C1[H])S([O-])(=O)=O
[H]N1N=NN=C1C1=C([H])C(F)=C([H])C(=C1[H])N(C(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C(OC(F)(F)F)=C1[H]
[H]N1N=NN=C1C1=C([H])C(F)=C([H])C(=C1[H])N(C(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C(F)(F)F
OC1=CC2=C(C=C1)N=C(N2C1=CC=NC(N[C@@H]2CCCN(C2)C(=O)C2CC2)=N1)C1=CC2=CC=CC=C2C=C1
[H]OC1=C(OC([H])([H])[H])C([H])=C(\C([H])=C(/[H])C2=C([H])C(=NN2[H])C([H])([H])[H])C([H])=C1OC([H])([H])[H]
[H]N(C1=NC([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C(C(=C([H])C([H])=C2[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]O[P@](=O)(C([H])([H])[C@@]([H])(C(=O)N([H])[C@@]([H])(C(=O)N([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])[C@@]([H])(N([H])C(=O)OC([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N1C([H])([H])C([H])([H])C([H])(C2=C([H])C([H])=NC(O[C@@]([H])(C3=C([H])C(Cl)=C([H])C([H])=C3[H])C(F)(F)F)=C2C([H])([H])[H])C([H])([H])C1([H])[H]
[H]OC(=O)C([H])([H])[C@]([H])(N([H])C(=O)C([H])([H])N([H])C(=O)C1=C([H])C(N([H])C2=NC([H])([H])[C@@]([H])(O[H])C([H])([H])N2[H])=C([H])C(O[H])=C1[H])C1=C([H])C(Cl)=C([H])C(=C1O[H])C([H])([H])[H]
[H]N(C(=O)[C@@]([H])(N([H])C(=O)OC([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])N([H])C1=C([H])C([H])=C([H])C(Cl)=C1[H]
[H]OC(=O)[C@@]1(F)[C@]2([H])C([H])([H])[C@@]([H])(OC([H])([H])C3=C([H])C(Cl)=C(Cl)C([H])=C3[H])[C@@](N([H])[H])(C(=O)O[H])[C@]12[H]
FC(F)(F)C1=CC=C(C(Cl)=C1)S(=O)(=O)NC1=CC(Cl)=C(OC2=CC3=CC=CC=C3N=C2)C(Cl)=C1
[H]N(C(=O)[C@]1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C(=O)N1C([H])([H])C([H])([H])N(C2=C([H])C([H])=C(F)C([H])=C2[H])C([H])([H])C1([H])[H])C([H])([H])C#N
[H]ON([H])C(=O)[C@]([H])(N1C([H])([H])C([H])([H])N([H])C2=C(C([H])=C([H])C(=C2[H])C2=C([H])C([H])=C([H])C([H])=C2C(F)(F)F)S1(=O)=O)C([H])([H])[H]
[H]N(\C(=N/C#N)N([H])[C@]([H])(N([H])C(=O)C([H])([H])C1=C([H])C([H])=C(F)C([H])=C1[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C([H])N=C1C([H])([H])[H]
[H]OC1=C([H])C([H])=C(C([H])=C1F)C1=NO[C@@]([H])(C([H])([H])C([H])([H])N2C(=O)C3=C(C([H])=C([H])C([H])=C3[H])C2=O)C1([H])[H]
[H]N1C(SC([H])([H])[H])=NC(=C1C1=C([H])C([H])=NC2=C([H])C([H])=C([H])C([H])=C12)C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]OC1=C(F)C([H])=C(C([H])=C1[H])C(=O)N([H])\N=C(/[H])C1=C([H])C(OC([H])([H])[H])=C(OC([H])([H])C2=C([H])C([H])=C(C([H])=C2[H])C([H])(C([H])([H])[H])C([H])([H])[H])C(OC([H])([H])[H])=C1[H]
[H]N([H])C(=O)[C@]1([H])C([H])([H])C([H])=C([H])C([H])([H])[C@]1([H])C(=O)N([H])C1=C([H])C(Cl)=C([H])C(Cl)=C1[H]
[H]OC(=O)C([H])([H])C([H])([H])C([H])([H])N([H])C(=O)C1=NC([H])=C([H])C(OC2=C([H])C([H])=C(N([H])C(=O)N([H])C3=C([H])C([H])=C(Cl)C(=C3[H])C(F)(F)F)C([H])=C2[H])=C1[H]
[H]OC1=C(N=C(N(C1=O)C([H])([H])[H])C(N([H])C(=O)C1=NN=C(O1)C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C(=O)N([H])C([H])([H])C1=C([H])C([H])=C(F)C([H])=C1[H]
CC(C)[C@@H]1N(C)C2=C(C[C@@H](CO)NC1=O)C=CC(=C2)[C]1234[B]567[B]89%10[B]%11%12%13[B]585[B]%118%11[B]%12%12%14[B]9%139[B]16%10[B]2%129[C]38%14[B]475%11
[H]N(C(=O)C1=C(N([H])C(C2=C([H])C([H])=C(C([H])=C2[H])N2C(=NC3=C(N=C(C([H])=C23)C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])=C(C(=O)OC([H])([H])C([H])([H])[H])[C@@]1([H])C1=C(Cl)C([H])=C([H])C([H])=C1[H])C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=N1
[H]OC(=O)C([H])([H])[C@]([H])(N1C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)OC([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C([H])([H])N=C(N([H])[H])N([H])[H])C([H])([H])C1([H])[H])C(=O)N([H])[C@]([H])(C(=O)OC([H])([H])[H])C([H])([H])[C@]12C([H])([H])[C@@]3([H])C([H])([H])[C@]([H])(C([H])([H])[C@]([H])(C3([H])[H])C1([H])[H])C2([H])[H]
[H]OC([H])([H])[C@@]([H])(N([H])C1=NC2=C(N=C([H])N2[C@]2([H])O[C@]([H])(C3=NN(N=N3)C([H])([H])C([H])([H])[H])[C@@]([H])(O[H])[C@@]2([H])O[H])C(=N1)N([H])[H])C([H])([H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]OC(=O)C([H])([H])N1C2=C([H])C([H])=C(C([H])=C2C(=C1C([H])([H])[H])S(=O)(=O)C1=C([H])C([H])=C(Cl)C([H])=C1[H])C([H])([H])[H]
[H]OC(=O)C([H])([H])C1=C([H])C2=C(OC([H])([H])C3=C([H])C([H])=C([H])C([H])=C3[C@@]2([H])SC([H])([H])C([H])([H])N2C([H])([H])C([H])([H])C([H])(C([H])([H])C3=C([H])C([H])=C([H])C([H])=C3[H])C([H])([H])C2([H])[H])C([H])=C1[H]
[H]N(C(=O)N([H])C1=C([H])C([H])=C([H])C(=C1[H])C1=C([H])C([H])=NC2=C([H])C(=NN12)C1=C([H])C([H])=NC([H])=C1[H])C1=C([H])C(=C(Cl)C([H])=C1[H])C(F)(F)F
[H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])[C@@]([H])(N(C([H])([H])C([H])([H])OC([H])(C2=C([H])C([H])=C(F)C([H])=C2[H])C2=C([H])C([H])=C(F)C([H])=C2[H])C([H])([H])[C@@]1([H])C([H])([H])[H])C([H])([H])[H]
[H]C1=NC(OC2=C([H])C([H])=C(OC(=O)N3C([H])([H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])C3([H])[H])C([H])=C2[H])=C([H])C([H])=C1C(F)(F)F
[H]N([H])C1=C(N=C(C([H])=N1)C1=C([H])C([H])=C(C([H])=C1C([H])([H])[H])S(=O)(=O)N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H])C(=O)N([H])C1=C([H])C([H])=C([H])N=C1[H]
[H]OC(=O)C(\[H])=C(/[H])C1=C(OC([H])([H])C([H])([H])C2=C([H])C([H])=C3C([H])=C([H])C([H])=C([H])C3=C2[H])C([H])=C(C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N1C([H])([H])[C@]2([H])C([H])([H])C([H])([H])[C@]([H])(C1([H])[H])[C@]2([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)C1=C([H])C2=C([H])C([H])=C([H])C([H])=C2N(C1=O)C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]O[C@]1([H])C2=C(N([H])C([H])=NC1([H])[H])N(C([H])=N2)C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C(=O)OC([H])([H])[H]
[H]N1C(=O)N([H])[C@]([H])(N2C(=O)C3=C([H])C([H])=C([H])C4=C([H])C([H])=C([H])C(C2=O)=C34)C1=O
[H]N(C(=O)N([H])C([H])([H])[H])C1=NC([H])=C([H])C(OC2=C([H])C([H])=C(N([H])C(=O)N3C(=O)N(C4=C([H])C([H])=C(F)C([H])=C4[H])C([H])([H])C3([H])[H])C([H])=C2[H])=C1[H]
[H]C1=C([H])C(=O)N2C([H])=C([H])C([H])=C(C3=NN=C(S3)N3C([H])([H])C([H])([H])C([H])(N4C([H])([H])C([H])([H])C([H])([H])C([H])([H])C4([H])[H])C([H])([H])C3([H])[H])C2=N1
[H]OC(=O)[C@@]([H])(N([H])C(=O)[C@@]1([H])N(C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C(OC([H])([H])[H])C([H])=C([H])C([H])=C1OC([H])([H])[H]
[H]OP(=O)(O[H])C(F)(C([H])([H])C1=C([H])C(=C([H])N=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H])P(=O)(O[H])O[H]
[H]O\N=C(\N([H])[H])C([H])([H])O\N=C(/C([H])([H])OC([H])([H])C1=C([H])C(=C([H])C(=C1[H])C(F)(F)F)C(F)(F)F)[C@@]([H])(C1=C([H])C([H])=C(Cl)C(Cl)=C1[H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C(O[H])(C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
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[H]OC([H])([H])C(\[H])=C(/[H])C1=C([H])C([H])=C2C(N=C([H])C(C#N)=C2N([H])C2=C([H])C([H])=C(SC3=NC([H])=C([H])N3C([H])([H])[H])C(Cl)=C2[H])=C1[H]
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[H]C1=C([H])C([H])=C(OC(=O)C2=C([H])C3=C([H])C(=C([H])C([H])=C3OC2=O)C([H])([H])Cl)C(I)=C1[H]
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[H]OC1=NSC(N([H])C2=C([H])C([H])=C(C([H])=C2[H])C(=O)OC([H])([H])[H])=C1C(=N[H])N([H])C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
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[H]OC(=O)C([H])([H])OC1=C([H])C([H])=C(\C([H])=C2/S\C(=N/C3=C([H])C([H])=C(OC([H])([H])[H])C([H])=C3[H])N(C2=O)C([H])([H])C([H])([H])C2=C([H])N([H])C3=C([H])C([H])=C([H])C([H])=C23)C([H])=C1[H]
[H]C1=C([H])C(=O)N(C([H])=C1Cl)C([H])([H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C([H])C(=NC(=N2)C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C(F)(F)F)C([H])([H])C1([H])[H]
[H]OC(=O)[C@]([H])(C([H])([H])C([H])([H])N1C(=O)C2=C(C([H])=C(OC([H])([H])C([H])([H])C([H])([H])[H])C([H])=C2[H])C1=O)C([H])([H])C1(C(=O)N([H])[C@]([H])(C(=O)N([H])C([H])([H])[H])C([H])([H])C2=C([H])C([H])=C(OC([H])([H])[H])C([H])=C2[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(C(=O)C([H])([H])C([H])([H])[H])C1=C([H])C(OC([H])([H])[H])=NC(SC([H])([H])C([H])([H])C([H])([H])[H])=N1
[H]O[C@](C(=O)N([H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C([H])C(OC([H])([H])[H])=C2[H])C([H])([H])C1([H])[H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]O[C@](C1=C([H])C([H])=C(C([H])=C1[H])C(=O)N(C1([H])C([H])([H])C1([H])[H])[C@@]1([H])C([H])([H])C([H])([H])[C@@](C2=C([H])C([H])=C(F)C([H])=C2[H])(C([H])([H])OC(=O)N([H])[H])C([H])([H])C1([H])[H])(C([H])([H])[H])C(F)(F)F
[H]OC(=O)[C@@]([H])(N([H])S(=O)(=O)C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C(N([H])C(=O)C2=C(C3=C(O2)C([H])=C([H])C(=C3O[H])C([H])([H])C([H])([H])[H])C([H])([H])[H])C([H])=C1[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N([H])C(=O)C1=C([H])C([H])=C(C([H])=C1[H])N1C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2=C([H])N([H])C3=C2C([H])=C(C([H])=C3[H])C(=O)N([H])[H])C([H])([H])C1([H])[H]
[H]N(C(=O)[C@@]([H])(N([H])C(=O)OC([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])N([H])C1=C([H])C([H])=C(OC2([H])C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])C([H])=C1[H]
[H]OC(=O)C([H])([H])C([H])([H])[C@]([H])(N1C(=O)C2=C([H])C([H])=C(C([H])=C2C1([H])[H])N(C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C2N=C(N=C(O[H])C2=C1[H])C([H])([H])[H])C(=O)O[H]
[H]N=C(N([H])[H])C1=C([H])C([H])=C([H])C(OC2=C(F)C(=C(F)C(OC3=C([H])C([H])=C([H])C(=C3[H])C(=O)C([H])(C([H])([H])[H])C([H])([H])[H])=N2)C([H])([H])[H])=C1[H]
CN1C=CN=C1C1CCCCN1C(=O)C1=C(OC2=CC=CC(Cl)=C2Cl)N(C)N=C1C
[H]N(C(=O)C([H])([H])[C@@]([H])(N([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C(F)(F)F)C1=C([H])C([H])=C(OC2=C([H])C([H])=NC3=C2SC(=C3[H])C2=C([H])N(C([H])=N2)C([H])([H])[H])C(F)=C1[H]
[H]OC1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[C@]1([H])N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@]([H])(N([H])[H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])SSC(C([H])([H])[H])(C([H])([H])[H])[C@@]([H])(N([H])C(=O)[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@]([H])(N([H])C1=O)[C@]([H])(O[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])C(=O)N([H])[C@]([H])(C(=O)N([H])[H])[C@]([H])(O[H])C([H])([H])[H]
[H]N1N=C(C([H])=C([H])C1=O)C1=C([H])C([H])=C(OC([H])([H])[H])N2N=C(C([H])=C12)C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)C([H])([H])N([H])C([H])([H])C([H])([H])N([H])C1=C2C(=NC3=C([H])C([H])=C([H])C([H])=C13)C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C1=C([H])C([H])=C2C3=C4C(C([H])=C([H])C([H])=C4C(=O)C2=C1[H])=C([H])C([H])=N3
[H]O[C@@](C([H])([H])N([H])C1=C2C([H])=NN(C2=C([H])C([H])=C1[H])C1=C([H])C([H])=C(F)C([H])=C1[H])(C([H])([H])N(C(=O)C1=C(Cl)C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])[H])C(F)(F)F
[H]N(C(=O)C([H])([H])N1N=C([H])C2=C1C1=C([H])C([H])=C([H])C([H])=C1OC2=O)C1=NC2=C([H])C([H])=C([H])C([H])=C2S1
[H]ON(C([H])=O)[C@@]([H])(C([H])([H])C([H])([H])C([H])([H])[H])[C@]([H])(C(=O)C([H])([H])[C@]([H])(C(=O)N([H])C1=S([H])C([H])=C([H])N1[H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=N\[N+]([O-])=O)\N([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N([H])S(=O)(=O)OC1=C([H])C(=C([H])C([H])=C1OC([H])([H])[H])C([H])([H])N(N1C([H])=NN=C1[H])C1=C([H])C([H])=C(C#N)C([H])=C1[H]
[H]OC(=O)C([H])([H])C1=C([H])C(I)=C(OC2=C([H])C([H])=C(O[H])C(I)=C2[H])C(I)=C1[H]
[H]N([H])C(=O)C1=C2C(=C([H])C([H])=C1[H])C([H])([H])C([H])([H])[C@@]1([H])N(C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[C@@]21[H]
[H]N(C1=C(OC2=C([H])C([H])=C(Cl)C([H])=C2[H])C([H])=NC([H])=C1[H])S(=O)(=O)C([H])([H])C([H])([H])[H]
[H]OC(=O)C1=C([H])C([H])=C([H])C(N([H])C2=C([H])C([H])=C([H])C([H])=C2[H])=C1[H]
[H]OC([H])([H])[C@@]1([H])O[C@@]([H])(OC2=C3C(N([H])C([H])=C3C([H])([H])C([H])([H])C3=C([H])C([H])=C4OC([H])([H])C([H])([H])C4=C3[H])=C([H])C([H])=C2[H])[C@]([H])(O[H])[C@@]([H])(O[H])[C@]1([H])O[H]
[H]N1C(=O)C([H])=C(C2=C1C(F)=C([H])C([H])=C2[H])C([H])([H])N(C(=O)C1=C([H])N=C([H])N1C([H])([H])[H])C1=C([H])C([H])=C([H])C(Cl)=C1[H]
[H]N([H])C1=N[C@]([H])(N(C(=N1)N([H])[H])C1=C([H])C([H])=C(Cl)C([H])=C1[H])C1=C([H])C(OC2=C([H])C([H])=C(Cl)C([H])=C2[H])=C([H])C([H])=C1[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C1=NOC(=N1)[C@]1([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C([H])([H])[C@@]1([H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]N1C([H])=C(C([H])=C1C([H])([H])N1C([H])([H])C([H])([H])N(C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N1C([H])([H])C([H])([H])C2=NC3=C([H])C([H])=NN3C(N3C([H])([H])C([H])(OC4=C([H])C([H])=C(OC([H])([H])[H])C([H])=C4[H])C3([H])[H])=C2C([H])([H])C1([H])[H]
[H]N([H])C(=O)[C@]([H])(N1C(=O)N(C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])[C@@]([H])(C1=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])[H])C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N([H])C(=O)C1=C([H])C([H])=C2C(N=C(N([H])C3=C([H])C([H])=C([H])C(Cl)=C3[H])C3=C2C([H])=NC([H])=C3[H])=C1[H]
[H]N(C(=O)C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])C1=C2C([H])=C([H])C([H])=C([H])C2=NC2=C1C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C1=NC(=C([H])S1)C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]OC1=C([H])C2=C(N([H])C(=C2[H])C2=C([H])N=C([H])C(=N2)C2=C([H])C([H])=C(C#N)C([H])=C2[H])C([H])=C1[H]
[H]ON([H])C(=O)C1(C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])S(=O)(=O)C1=C([H])C([H])=C(OC([H])([H])C([H])([H])C([H])([H])N2N=NC(=N2)C2=C([H])C([H])=C(OC(F)(F)F)C([H])=C2[H])C([H])=C1[H]
[H]OC(=O)[C@]([H])(N1C([H])([H])[C@]([H])(C2=C([H])C(F)=C([H])C([H])=C2[H])[C@@]([H])(C([H])([H])N2C([H])([H])C([H])([H])C([H])(C3=C([H])C(=NN3C([H])([H])C([H])([H])[H])C([H])([H])C3=C([H])C([H])=C(C([H])=C3[H])S(=O)(=O)C([H])([H])[H])C([H])([H])C2([H])[H])C1([H])[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
N[C@@H](CCCNC(=N)NN(O)=O)C(=O)N[C@@H]1CN[C@H](C1)C(N)=O
[H]N(C(=O)[C@@]([H])(N1C(=O)C(=NC2=C([H])C([H])=C([H])C([H])=C12)C1=C([H])C([H])=C([H])O1)C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C1=C(C(=O)C2([H])C(C([H])([H])[H])(C([H])([H])[H])C2(C([H])([H])[H])C([H])([H])[H])C2=C(C([H])=C([H])C([H])=C2N1C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])[N+]([O-])=O
[H]C1=C([H])C(=C([H])C(F)=C1N1C([H])([H])C([H])([H])N(C(=O)C2=C([H])C(=C([H])C([H])=C2OC([H])([H])C2([H])C([H])([H])C2([H])[H])S(=O)(=O)C([H])([H])[H])C([H])([H])C1([H])[H])S(=O)(=O)C([H])([H])[H]
[H]C1=C([H])C(=C([H])S1)C(=O)[C@@]1([H])OC(=O)[C@]2([H])C([H])([H])C([H])([H])[C@@]3(C([H])([H])[H])[C@]([H])(C(=O)OC([H])([H])[H])C([H])([H])[C@]([H])(OC(=O)C([H])([H])[H])C(=O)[C@]3([H])[C@@]2(C([H])([H])[H])C1([H])[H]
OC1=CC=C(C(=O)\C=C\C=C\C2=CC=C(Cl)C=C2)C(O)=C1
[H]OC([H])([H])C1=C([H])C2=C(N=C(S2)C(=O)[C@]([H])(N([H])C(=O)[C@@]2([H])N(C(=O)[C@]([H])(N([H])C([H])([H])[H])C([H])([H])C3=C([H])C([H])=C([H])C([H])=C3[H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=N[H])N([H])[H])C([H])=C1[H]
[H]OC(=O)C([H])([H])[C@]([H])(N([H])C(=O)C1=C([H])SC(=C1[H])C([H])([H])N([H])C(=O)C1=C([H])C([H])=C(N([H])C2=NC3=C([H])C([H])=C([H])C([H])=C3N=C2[H])C([H])=C1[H])C([H])=O
[H]OC(=O)[C@@]([H])(N([H])S(=O)(=O)C1=C([H])C([H])=C2C(SC3=C2C([H])=C([H])C(=C3[H])N2C(=O)OC([H])([H])C2([H])[H])=C1[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H][C@]12CCCO[C@@]1([H])C1=CC(CCCCC)=CC=C1N[C@H]2C1CCCCC1
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[H]N(C(=O)C1=NOC(=C1[H])C1=C([H])C([H])=C([H])C([H])=C1OC([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])O1
[H]N(C(=O)C(\[H])=C(/[H])C1=C([H])C([H])=C(C([H])=C1[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C(OC([H])([H])[H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N([H])C1=NC(=C([H])C(=N1)C1=C(Cl)C([H])=C(Cl)C([H])=C1[H])C([H])([H])[H]
[H]N1C(=C([H])C2=C(C([H])=C([H])C([H])=C12)C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H])C1=NOC(=N1)C([H])([H])C([H])([H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
COC1=CC=C2C(SC3=C2N=CN=C3NC2=CC=C(Cl)C=C2Cl)=C1
[H]N1C([H])([H])C([H])([H])[C@@]([H])(C2=C(C([H])=C([H])C(Cl)=C2[H])C2=C([H])C(Cl)=C([H])C([H])=C2[H])C1([H])[H]
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[H]C1=C([H])C(=C([H])C2=C1OC1=C([H])C(=C([H])C([H])=C1S2(=O)=O)C(=O)C([H])([H])[H])C(=O)C([H])([H])[H]
[H]OC1=C(C(OC([H])([H])[H])=C(C2=C1C(=O)OC2([H])[H])C([H])([H])[H])C([H])([H])C(\[H])=C(/C([H])([H])[H])C([H])([H])N(C([H])([H])[H])C([H])([H])C([H])([H])P(=O)(O[H])O[H]
[H]C1=C([H])C(=C([H])C([H])=C1Br)C(=N/OC([H])([H])[H])\C1([H])C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])C1(C([H])([H])[H])C([H])([H])C([H])([H])N(C(=O)C2=C([N+]([O-])=C([H])C([H])=C2C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N(C1=NC(Cl)=C([H])N(C1=O)C([H])(C([H])([H])OC([H])([H])[H])C([H])([H])OC([H])([H])[H])C1=C(Cl)C([H])=C(C([H])=C1Cl)C(F)(F)F
ONC(=O)CCCCCNC(=O)NC(=O)C1=CC(=C(C=C1)N1CCOCC1)N(O)=O
[H]N1C2=C(C(=NN2C2=C(C([H])=C([H])C([H])=C2[H])C(F)(F)F)C([H])([H])[H])[C@@]([H])(S[C@]([H])(C1=O)C([H])([H])[H])C1=C([H])C([H])=C(OC2=C([H])C([H])=C([H])C([H])=C2[H])C([H])=C1[H]
[H]ON([H])C(=O)[C@]([H])(N(C([H])([H])C1=C([H])C([H])=C2C([H])=C([H])C(OC([H])([H])C([H])=C([H])[H])=C([H])C2=C1[H])S(=O)(=O)C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])C([H])([H])[H]
[H]C1=C([H])N2C(=C1[H])[C@@]([H])(N(C(=O)C([H])([H])N(C(=O)[C@]([H])(Cl)C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])C1=C2C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]N(C1=C2C([H])=C([H])C([H])=C([H])C2=C(N=N1)C1=C([H])C([H])=C([H])C2=C([H])N=C([H])C([H])=C12)C1=C([H])C([H])=C(C([H])=C1[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]OC1=C2N=C3C([H])=C([H])C([H])=C([H])C3=C2C([H])=C(N1C([H])([H])C(=O)N([H])[C@@]([H])(C(=O)C(F)(F)F)C([H])(C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]O[C@]([H])(C1=C([H])C([H])=C([H])N=C1[H])C([H])([H])N([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C(N([H])S(=O)(=O)C2=C([H])C([H])=C(C([H])=C2[H])N2N=C([H])C(=N2)C([H])([H])C2=C([H])C(F)=C([H])C([H])=C2[H])C([H])=C1[H]
[H]OC(=O)C1=C([H])C([H])=C(C([H])=C1[H])N1N=C([H])C(C(=O)N([H])[C@@]2([H])[C@@]3([H])C([H])([H])[C@]4([H])C([H])([H])[C@]([H])(C3([H])[H])C([H])([H])[C@@]2([H])C4([H])[H])=C1C1([H])C([H])([H])C([H])([H])C1([H])[H]
[H]OC(=O)C1=C([H])C([H])=C(OC2=C(N([H])C(=O)C3=NC([H])=C([H])C(=C3[H])[N+]([O-])=O)C([H])=C([H])C([H])=C2[H])C([H])=C1C(=O)O[H]
[H]OC([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=NC(=C([H])N=C2N(C([H])([H])[H])C([H])([H])[H])C2=C([H])C([H])=NC([H])=C2[H])C([H])([H])C1([H])[H]
[H]N1C([H])([H])C([H])([H])C(=C(C2=C([H])C([H])=C(C([H])=C2[H])C(=O)N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H])C2=C([H])C(F)=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]C1=C([H])C(=C([H])C([H])=C1OC([H])([H])[H])C(=O)N(C([H])([H])[H])[C@]1([H])C([H])([H])C([H])([H])N(C(=O)C2([H])C([H])([H])C([H])([H])N(C(=O)C([H])([H])[H])C([H])([H])C2([H])[H])C([H])([H])[C@]1([H])C1=C([H])C([H])=C(Cl)C(Cl)=C1[H]
[H]O[C@@]1([H])C([H])([H])[C@]([H])(O[C@]1([H])OP([O-])([O-])=O)N1C([H])=C(C(=O)C([H])([H])Br)C(=O)N([H])C1=O
[H]OC(=O)[C@]([H])(SC1=NC(OC([H])([H])C([H])([H])C2([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])=C([H])C(OC([H])([H])C([H])([H])C2([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])=N1)C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]O[C@]1(C2=C([H])C([H])=C(F)C(F)=C2[H])C([H])([H])C([H])([H])N([H])C([H])([H])[C@]1([H])C1=C(C([H])=C(C([H])=C1[H])C1=C(C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])N([H])C(=O)C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C(F)C([H])=C1[H])C1=C([H])C([H])=C2OC([H])=C(C2=N1)C1([H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N(\N=C(\C1=C([H])C([H])=NC([H])=C1[H])C([H])([H])[H])C1=C2C(=NC([H])=N1)N(N=C2C([H])([H])[H])C1=C([H])C(OC([H])([H])[H])=C([H])C([H])=C1[H]
[H]SC([H])([H])C([H])([H])C([H])([H])S(=O)(=O)C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]OC1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[C@@]([H])(N([H])C(=O)[C@@]([H])(C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])[P@](=O)(O[H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)C1=C([H])C([H])=C([H])C([H])=C1[H])C(=O)N([H])C([H])([H])[H]
OC(=O)[C@H](CC1=CC=C(NC(=O)C2=C(Cl)C=NC=C2Cl)C=C1)NC(=O)[C@@H]1C[C@H](CN1S(=O)(=O)C1=CC=CC(=C1)C#N)N1CCC(F)(F)CC1
[H]OC(=O)C([H])([H])[C@@]1([H])C2=C(C([H])=C(OC([H])([H])C([H])([H])C3=C(N=C(N3C([H])([H])[H])C3=C([H])C([H])=C(C([H])=C3[H])C3=C([H])C([H])=C([H])C([H])=C3[H])C([H])([H])[H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N(C(=O)C([H])([H])N1C([H])([H])C([H])([H])N(C2=C3N=C(N([H])C3=NC([H])=C2C#N)C2=C([H])C([H])=C(C([H])=C2[H])N(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H])C1=NC([H])=C([H])S1
[H]C([H])([H])C1=NC(=NC(=C1C(=O)N1C([H])([H])C([H])([H])C(N2C([H])([H])C([H])([H])[C@]3(OC(=O)N(C([H])([H])C4([H])C([H])([H])C([H])([H])OC([H])([H])C4([H])[H])C([H])([H])[C@]3([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C2([H])[H])(C([H])([H])[H])C([H])([H])C1([H])[H])C([H])([H])[H])C(F)(F)F
[H]OC(=O)[C@@]([H])(N([H])C(=O)C1=C([H])C([H])=C([H])C([H])=C1OC1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])N(C(=O)C([H])([H])C([H])([H])C2([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C2=C([H])C(Cl)=C([H])C([H])=C12
[H]C1=NC(=C([H])C([H])=C1[H])C1=NN=C(N2C([H])([H])C([H])([H])N(C(=O)C3=C([H])C([H])=C([H])C([H])=C3[H])C([H])([H])[C@@]2([H])C([H])([H])[H])C2=C([H])C([H])=C([H])C([H])=C12
[H]OC1(C2=C([H])C(=C([H])C([H])=C2[H])C([H])([H])OC2=C([H])C([H])=C3C(C([H])=C4C(=O)OC([H])([H])C4=C3C3=C([H])C([H])=C([H])C(OC([H])([H])[H])=C3[H])=C2[H])C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]N1C(SC2=C([H])C([H])=C([H])C([H])=C2[H])=C2C3=C(C([H])=C([H])C([H])=C13)[C@@]1([H])C([H])([H])[C@@]([H])(C([H])([H])[H])C([H])([H])N(C([H])([H])[H])[C@]1([H])C2([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C(Cl)C([H])=C1[H])[C@]1([H])C2=C([H])C(=C([H])C([H])=C2C([H])([H])C1([H])[H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=NSC3=C([H])C([H])=C([H])C([H])=C23)C([H])([H])C1([H])[H]
[H]C#CC(=O)N([H])C1=C([H])C2=C(N=C([H])N=C2C([H])=N1)N([H])C1=C([H])C([H])=C([H])C(Br)=C1[H]
[H]O[C@@]1(C(=C([H])[C@@]([H])(OC(=O)C([H])([H])[H])[C@@]2(C([H])([H])[H])[C@]1([H])C([H])([H])C([H])([H])[C@@]1(C([H])([H])[H])[C@@]3([H])C([H])=C([H])C([H])([H])OC([H])([H])[C@]3([C@]([H])(OC(=O)C([H])([H])[H])C([H])([H])[H])[C@@]([H])(OC(=O)C([H])([H])[H])[C@@]([H])(OC(=O)C([H])([H])[H])[C@]21[H])C([H])([H])[H])C([H])([H])C(=C([H])[H])C1=C(C([H])=C([H])C([H])=C1[H])[S@@](=O)OC([H])([H])[H]
[H]O[C@@]([H])(C([H])([H])[C@]([H])(C(=O)N([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])[H])[C@@]([H])(N([H])[H])C([H])([H])N(C(=O)C1=C([H])C(OC([H])([H])C([H])([H])C([H])([H])OC([H])([H])[H])=C(C([H])=C1[H])C([H])([H])C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]OC(=O)[C@]([H])(N([H])[H])C([H])([H])C([H])([H])C(C1=C([H])C([H])=C([H])C([H])=C1[H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC(=O)C(C1=C2C([H])=C([H])C([H])=C([H])C2=C(N=C1[H])C(=O)C1=C([H])C([H])=C(C([H])=C1[H])C(=O)N([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C(Cl)C([H])=C1[H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)N1C([H])([H])C([H])([H])C([H])(N2C(=O)N([H])C3=C2C([H])=C([H])C([H])=N3)C([H])([H])C1([H])[H])[C@@]1([H])C(=O)N(C([H])([H])C([H])([H])SC([H])([H])[H])C([H])([H])[C@]([H])(C2=C([H])C([H])=C([H])C(F)=C2F)C([H])([H])C1([H])[H]
[H]N1C([H])([H])C([H])([H])N(C2=C([H])C([H])=C([H])C([H])=C2C2=C([H])C([H])=C(OC([H])([H])[H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]OC(=O)C(OC1=C(C([H])=C(SC([H])([H])C2=NC(=NS2)C2=C([H])C([H])=C(Cl)C([H])=C2[H])C([H])=C1[H])C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]N1N([H])\C(C([H])=C1C1=C([H])C([H])=C([H])C([H])=C1Cl)=C1\C([H])=C([H])C(=C([H])C1=O)C([H])([H])[H]
[H]N(C1=NC2=C(Cl)C([H])=C([H])C([H])=C2N2C1=NN=C2C([H])([H])C([H])([H])[H])[C@@]([H])(C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC(=O)C([H])([H])[C@@]1(ON=C(C2=C([H])C(=C([H])C([H])=C2[H])C(=N[H])N([H])[H])C1([H])[H])C(=O)N([H])C1=C([H])C([H])=C(C([H])=C1[H])C(=N[H])N([H])[H]
[H]N(C1=C([H])C2=C(OC3(C([H])([H])C2=O)C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C2=C([H])C4=NON=C4C([H])=C2[H])C([H])([H])C3([H])[H])C([H])=C1[H])S(=O)(=O)C([H])([H])[H]
[H]C1=C([H])C(=C([H])C(=C1[H])C(F)(F)F)C([H])([H])N1C([H])([H])C([H])([H])C(=O)[C@]([H])(C1([H])[H])C([H])(C1=C([H])C([H])=C(F)C([H])=C1[H])C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]N(C(=O)C(\C#N)=C(/[H])C1=C([H])N([H])C2=C([H])C([H])=C([H])C([H])=C12)C([H])([H])[C@@]1([H])OC([H])([H])C([H])([H])C1([H])[H]
[H]N(C(=O)[C@@](N([H])C(=O)OC([H])([H])C1=C([H])C2=C(S1)C([H])=C([H])C([H])=C2[H])(C([H])([H])[H])C([H])([H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H])[C@]([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H]
[H]N1C2=NC([H])=C([H])C([H])=C2N=C1C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=N1
[H]C1=C([H])C2=C(C([H])=C1[H])C(=O)[C@@]([H])(C([H])([H])C1=C([H])C([H])=C(Cl)C([H])=C1[H])C([H])([H])O2
[H]C1=C([H])C(=C([H])C([H])=C1F)[C@@]1([H])N(N=C(C2=C([H])C([H])=C(Br)C([H])=C2[H])C1([H])[H])C1=NC(=O)C([H])([H])S1
[H]N([H])C1=C([H])C([H])=C([H])C(=N1)C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])[H])[C@@]1([H])C2=NC([H])=C([H])C([H])=C2C([H])([H])C([H])([H])C1([H])[H]
[H]C([H])=C([H])C([H])([H])N1C2=C([H])C([H])=C(C([H])=C2C2=C1C1=C(C3=C([H])N(N=C3C([H])([H])C1([H])[H])C([H])([H])[H])C1=C2C([H])([H])N([H])C1=O)[C@@]1([H])OC([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(C([H])([H])C1(F)C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])S(=O)(=O)C1=C(C([H])=C(Cl)C([H])=C1[H])S(=O)(=O)C1=C([H])C([H])=C([H])C([H])=C1F)S(=O)(=O)C(F)(F)F
[H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C(=O)C([H])([H])C2=C([H])C(Cl)=C(Cl)C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N(C1=C2C([H])=NN(C2=NC([H])=N1)C([H])([H])[C@]([H])(Cl)C1=C([H])C([H])=C(F)C([H])=C1[H])C([H])([H])C1=C([H])C(Cl)=C([H])C([H])=C1[H]
[H]N1C([H])=NC(=C1C1=C([H])C2=C(C([H])=C1[H])N(C(=O)N2C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H])C1=C([H])C([H])=C([H])C(=C1[H])C([H])([H])[H]
[H]N(C(=O)C1=C([H])C(OC2=C(C([H])=C([H])C([H])=C2[H])C([H])([H])[H])=C([H])C([H])=C1[H])C1=NC(=C([H])S1)C([H])([H])[H]
[H]OC(=O)[C@]([H])(N([H])S(=O)(=O)C1=C([H])C([H])=C2C(SC3=C2C([H])=C(N([H])C(=O)OC([H])([H])[H])C([H])=C3[H])=C1[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)N([H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])[C@@]([H])(C([H])([H])C2=C([H])C([H])=C(F)C([H])=C2[H])C1([H])[H])C1=C([H])C(=C([H])C(=C1[H])C1=NN=NN1C([H])([H])[H])C([H])([H])[H]
CC(=O)N1N=C(CC1C1=CC=CC=C1)C1=CC2=C(Br)C=CC=C2OC1=O
[H]N1C([H])([H])C([H])([H])C([H])(C([H])([H])C(=O)N2C([H])([H])C([H])([H])N(C([H])([H])C2([H])[H])[C@]2([H])C3=C(C([H])=C([H])C([H])=N3)C([H])([H])SC3=C2C([H])=C([H])C(Cl)=C3[H])C([H])([H])C1([H])[H]
[H]C1=C([H])C([H])=C(C(=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C(F)(F)F)C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C([H])([H])[C@]([H])(N2C([H])([H])C([H])([H])N(C([H])([H])C2([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])C2=C([H])C([H])=C(F)C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N=C(N([H])C1=C(Cl)C(=C([H])C(Cl)=C1[H])C(F)(F)F)N(C1=C([H])C([H])=C([H])C(=C1[H])C([H])([H])C([H])([H])[H])C([H])([H])[H]
[H]OC1=C([H])C([H])=C2C([H])=C(N([H])C2=C1[H])C(=O)N1C([H])([H])C([H])([H])C([H])(C([H])([H])C1([H])[H])[C@]([H])(O[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C1=C(C2=C([H])C(Cl)=C([H])C([H])=C2N1C1=C([H])C([H])=C(F)C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H]
[H]N(C1=C2C([H])=C(C([H])=C([H])C2=NC([H])=N1)C1=C([H])C2=C(OC([H])([H])O2)C([H])=C1[H])C([H])([H])C1=C([H])C(=C([H])C([H])=C1[H])C([H])([H])[H]
[H]N(C(=O)O[C@]1([H])C([H])([H])[C@]2([H])N(C([H])([H])[H])[C@@]([H])(C([H])([H])C2([H])[H])[C@]1([H])C(=O)OC([H])([H])[H])C1=C([H])C([H])=C(N=[N+]=[N-])C([H])=C1[H]
[H]OC(=O)[C@@]1([H])N2C3=C(C([H])=C([H])C([H])=C3C([H])([H])C([H])([H])[C@@]([H])(N([H])C(=O)[C@@]([H])(S[H])C([H])([H])C3=C([H])C([H])=C(C([H])=C3[H])C3=C([H])C([H])=C([H])C([H])=C3[H])C2=O)C1([H])[H]
[H]OC1=C([H])C(=C([H])C(O[H])=C1C1=C([H])C([H])=C([H])C([H])=C1[H])C(=O)OC([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]OC1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[C@]1([H])N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])[H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])SSC([H])([H])[C@@]([H])(N([H])C(=O)[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@]([H])(N([H])C1=O)C([H])([H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])C(=O)N([H])[C@]([H])(C([H])=O)[C@]([H])(O[H])C([H])([H])[H]
[H]OC(=O)[C@@]([H])(C1=C([H])C2=C(C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1N2[H])C([H])([H])[H]
[H]O[C@@]1(C(=C([H])[C@@]([H])(OC(=O)C([H])([H])[H])[C@@]2(C([H])([H])[H])[C@@]1([H])C([H])([H])C([H])([H])[C@@]1(C([H])([H])[H])[C@@]3([H])C([H])=C([H])C([H])([H])OC([H])([H])[C@]3([C@]([H])(OC(=O)C([H])([H])[H])C([H])([H])[H])[C@@]([H])(OC(=O)C([H])([H])[H])[C@@]([H])(OC(=O)C([H])([H])[H])[C@]21[H])C([H])([H])[H])C([H])([H])C(=C([H])[H])C1=C(SC([H])([H])[H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)OC1=C([H])C([H])=C2N(C([H])=C(C2=C1[H])C([H])([H])[H])N(C1=C([H])C([H])=NC([H])=C1F)C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])[H]
[H]OC(=O)C([H])([H])N1C([H])=C(C([H])=NC1=O)C([H])([H])C1=C([H])N(C(SC([H])([H])C2=C([H])C([H])=C(F)C([H])=C2[H])=NC1=O)C([H])([H])C(=O)N(C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]OC(=O)[C@]([H])(N(C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1C2=C(N=C1C([H])([H])C([H])([H])[H])C(=C([H])C(=N2)C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
CCCN(C1=NOC=C1)P(=O)(C1=CC=CC=C1)C1=CC=CC=C1
[H]OC1=NC2=C([H])C(Cl)=C([H])C([H])=C2C(OC([H])([H])[C@]2([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C2([H])[H])=C1C1=C([H])C(=C([H])C(=C1[H])C([H])([H])[H])C([H])([H])[H]
[H]\C(C1=C([H])C([H])=C(C([H])=C1[H])N(C([H])([H])[H])C([H])([H])[H])=C1/C(=O)/C(=C(\[H])C2=C([H])C([H])=C(C([H])=C2[H])N(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C1([H])[H]
[H]C1=C([H])C(Cl)=C(C([H])=C1[H])C1=NC(=C2N1C1=NC(OC([H])([H])[H])=C([H])C([H])=C1N=C2C#N)C([H])([H])[H]
CN1CCN(CC1)C1=C2C=C(NC2=NC(N)=N1)C1=CC=CC=C1
[H]N=C(N([H])[H])N(C([H])([H])[H])C([H])([H])C(=O)N([H])C1=C(I)C([H])=C(C([H])=C1[H])S(=O)(=O)N([H])[H]
[H]N(C(=O)OC([H])([H])C1=C([H])N([H])N=C1[H])[C@]([H])(C([H])([H])N(C([H])([H])C([H])([H])[H])C([H])([H])[C@@]([H])(N([H])C(=O)OC([H])([H])C1=C([H])N([H])N=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N([H])N1C(SC([H])([H])C([H])([H])C([H])([H])N2C([H])([H])C([H])([H])N(C3=NC([H])=C([H])C([H])=N3)C([H])([H])C2([H])[H])=N[C@]2([H])SC(=C([H])[C@]2([H])C1=O)C([H])([H])C([H])([H])[H]
[H]N(C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C1=C([H])C([H])=NC([H])=C1[H])C1=C(C#N)C([H])=NC2=C([H])C(OC([H])([H])C([H])([H])C([H])([H])N3C([H])([H])C([H])([H])OC([H])([H])C3([H])[H])=C(OC([H])([H])[H])C([H])=C12
[H]N1C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])[C@]([H])(C1=C([H])C([H])=C(F)C([H])=C1[H])C([H])([H])C1=C(OC([H])([H])C([H])([H])[H])C([H])=C([H])C([H])=C1[H]
[H]C1=C([H])C([H])=C(C([H])=N1)[C@]([H])(C1=C(C(=O)C(=C(C1=O)C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])OC(=O)C([H])([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C(F)C([H])=C1[H])C1=C([H])C(I)=C([H])C([H])=C1SC1=C([H])C([H])=C([H])C([H])=C1C([H])([H])N(C([H])([H])[H])C([H])([H])[H]
[H]OC1=C([H])C([H])=C(C2=C1N([H])C(=O)S2)[C@@]([H])(O[H])C([H])([H])N([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C(=C1[H])C([H])([H])C([H])([H])N([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1OC([H])([H])[H]
[H]N(C(=O)N([H])[C@@]1([H])C(=O)N(C2=C(C([H])=C([H])C(=C2[H])C([H])([H])[H])[C@@]([H])(C2=C([H])C([H])=C(C([H])=C2[H])C([H])([H])[H])C1([H])[H])C([H])([H])C(=O)N([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C1=C([H])C(Cl)=C([H])C([H])=C1[H]
[H]N(C(=O)C1=NN(C(=C1C([H])([H])[H])C1=C([H])C([H])=C(Cl)C([H])=C1[H])C1=C([H])C([H])=C(Cl)C([H])=C1Cl)C(=O)C1([H])C([H])([H])C([H])([H])C1([H])[H]
[H]OC1=C([H])C(=O)C2=C(N1[H])C(C#N)=C(SC([H])([H])C(=O)N([H])C1=C([H])C(F)=C([H])C([H])=C1[H])S2
CN1N=C(C)C(C(=O)N(CC2=CN=CC=C2)C2CC2)=C1OC1=CC=CC(Cl)=C1Cl
[H]N(C(=O)N([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC(O[C@]2([H])C([H])([H])OC([H])([H])C2([H])[H])=NC(=N1)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C(=O)N(C([H])([H])[H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H]
[H]C1=C(OC(=C1[H])C([H])([H])[N+](C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H]
[H]SC([H])([H])[C@]([H])(N([H])C(=O)C1=C([H])SC([H])=C1[H])C(=O)N([H])[C@]([H])(C(=O)N([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC(=O)C([H])([H])C([H])([H])[C@@]1([H])N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@]([H])(N([H])C(=O)[C@]([H])(C(=O)C([H])([H])[H])C([H])([H])C(=O)\N=C(N([H])[H])/N([H])C([H])([H])C([H])([H])C([H])([H])[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])C1=O)C([H])([H])C1=C([H])C([H])=C(O[H])C([H])=C1[H])C(=O)N([H])[H])[C@@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])[C@]([H])(O[H])C([H])([H])[H])C([H])([H])C([H])([H])SC([H])([H])[H]
[H]ON([H])C(=O)C([H])([H])N(C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])[N+]([O-])=O)S(=O)(=O)C1=C([H])C([H])=C(N([H])C(=O)N([H])S(=O)(=O)C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])=C1[H]
[H]N1N=C([H])C2=C([H])C(=C([H])C([H])=C12)N1N=NC(=C1[H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]N(\C(=N/C#N)N([H])[C@]([H])(N([H])C(=O)C([H])([H])C1=C([H])C([H])=C([H])C2=C([H])C([H])=C([H])C([H])=C12)C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C([H])C2=NC([H])=C([H])C([H])=C12
[H]C1=NC2=C([H])C([H])=C([H])C([H])=C2C(=C1[H])N1C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N2C([H])([H])C([H])([H])N(C3=C([H])C([H])=C([H])C([H])=C3[H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])N(C([H])([H])C1=C([H])C([H])=C(F)C([H])=C1C(F)(F)F)C1([H])C([H])([H])C([H])([H])N([H])C([H])([H])C1([H])[H]
[H]OC1=NN=C(SC2=NC([H])=C(S2)[N+]([O-])=O)N1C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C1=NC(=NC2=C1N=C([H])N2C([H])(C([H])([H])[H])C([H])([H])[H])N([H])[C@@]1([H])C([H])([H])C([H])([H])[C@]([H])(N([H])C(=O)C([H])([H])[H])C([H])([H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
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[H]C1=NC([H])=C(C([H])=C1C1=C([H])C2=C([H])C([H])=C(OC([H])([H])[H])C([H])=C2C([H])=C1[H])C([H])([H])OC([H])([H])[H]
[H]C1=NC(=C([H])S1)C([H])([H])N1C([H])([H])C([H])([H])C([H])(OC2=C3C([H])=C([H])N(C3=NC([H])=N2)C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2F)C([H])([H])C1([H])[H]
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[H]N(C1=C(SC2=C([H])C([H])=C([H])C([H])=N2)C([H])=C2C(=O)C([H])([H])C([H])([H])C2=C1[H])S(=O)(=O)C([H])([H])[H]
[H]C([H])([H])[N+]1=C(C(C(=O)OC([H])([H])C([H])([H])[H])=C(C(C(=O)SC([H])([H])C([H])([H])[H])=C1C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]OC(=O)C1=C(OC([H])([H])C(=O)O[H])C(Br)=C(S1)C1=C([H])C(N([H])C([H])([H])C2([H])C([H])([H])C([H])([H])N(C(=O)N([H])C3=C(C([H])=C([H])C([H])=C3C([H])([H])[H])C([H])([H])[H])C([H])([H])C2([H])[H])=C([H])C([H])=C1[H]
[H]\C(=C1\SC2=NC(=NN2C1=O)C1=C([H])C([H])=C([H])O1)C1=C(OC([H])([H])[H])C([H])=C([H])C(Br)=C1[H]
[H]C1=C([H])C([H])=C2C(=O)C(=O)N(C2=C1[H])C([H])([H])C1=C([H])C([H])=C(Br)C([H])=C1[H]
[H]N(C(=O)C(\[H])=C(/[H])C1=C2OC([H])([H])C([H])([H])C2=C([H])C(=C1[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(N([H])S(=O)(=O)C([H])([H])[H])C(F)=C1[H]
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[H]N(C1=NC2=C(O1)C([H])=C([H])C([H])=C2N([H])C([H])([H])C(F)(F)C1=C([H])C([H])=C([H])C([H])=N1)C1=C([H])C(Cl)=C([H])C([H])=C1[H]
[H]N(C(=O)C([H])([H])N1C(=O)N(C2=C1C([H])=C([H])C([H])=C2[H])C1=NC([H])=C([H])C([H])=C1[H])C1=C([H])C2=C(C([H])=C1[H])C([H])([H])[C@]1(N=C(N([H])C1=O)C1=C([H])N=C([H])C([H])=C1[H])C2([H])[H]
[H]C1=C2C(=C([H])S1)[C@]1(O[C@@]([H])(OC([H])([H])[H])C2([H])[H])C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N([H])C1=NC([H])=C([H])N2C(=NC(=C12)C1=C([H])C(OC([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])=C([H])C([H])=C1[H])[C@@]1([H])C([H])([H])C([H])([H])[C@]([H])(C(=O)N([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N(C1=NC([H])=NC2=C1C(OC([H])([H])C([H])([H])N1OC([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])=NN2[H])C1=C([H])C([H])=C(OC([H])([H])C2=NC([H])=C([H])C([H])=C2[H])C(Cl)=C1[H]
[H]\C(=C(\[H])C1=C(SC([H])([H])[H])C([H])=C([H])C([H])=C1[H])C(=O)N([O-])C([H])([H])[H]
[H]N(C(=O)C1=C([H])C2=C(C([H])=C3N2C([H])([H])C([H])([H])C([H])([H])N([H])C3=O)C([H])=C1[H])C1=C([H])C(Cl)=C([H])C([H])=C1[H]
[H]N(C1=NC(=C([H])C2=C1C(=O)N([H])C([H])=C2[H])C1=NC(=C([H])C([H])=C1[H])N1C([H])=NC(=C1[H])C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]N([H])S(=O)(=O)C1=NN=C(S1)N([H])S(=O)(=O)C1=C([H])C([H])=C(N([H])S(=O)(=O)C2=C(F)C(F)=C(F)C(F)=C2F)C([H])=C1[H]
[H]C1=C(OC(=O)C([H])([H])C([H])([H])C([H])([H])N2C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])C2=C(OC(C([H])([H])[H])(C([H])([H])[H])[C@]3([H])C([H])([H])C([H])=C(C([H])([H])[H])C([H])([H])[C@@]23[H])C([H])=C1C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C#N
[H]OC([H])([H])[C@@]1([H])O[C@@]([H])(N2C([H])=NC3=C(N=C([H])N=C23)N([H])[C@@]2([H])C3=C(C([H])=C(OC([H])([H])C([H])([H])[H])C([H])=C3[H])C([H])([H])C2([H])[H])[C@]([H])(O[H])[C@]1([H])O[H]
[H]N(C1=NN=C([H])N1C1=C(Cl)C(Cl)=C([H])C([H])=C1[H])C([H])([H])C1=C(N=C([H])C([H])=C1[H])N1C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C1([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)N1C([H])([H])C([H])([H])N(C2=NC([H])=C(C([H])=C2Cl)C(=O)OC([H])([H])[H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC1=C([H])C([H])=C(OC([H])([H])[C@@]([H])(O[H])C([H])([H])N([H])C([H])([H])C([H])([H])C2=C([H])C([H])=C(N([H])C3([H])C([H])([H])C([H])([H])N(C(=O)N([H])C([H])([H])C4=C([H])C([H])=C([H])C([H])=C4F)C([H])([H])C3([H])[H])C([H])=C2[H])C([H])=C1[H]
[H]N([H])C(=O)C1=C([H])C([H])=C(OC2=C([H])C([H])=C(\C([H])=C3/SC(=S)N(C3=O)C3=C([H])C([H])=C(OC([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N4C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C4([H])[H])C([H])=C3[H])C([H])=C2[H])C([H])=C1[H]
[H]N(C1=NC(=C([H])C([H])=C1C#N)C([H])([H])O[C@@]([H])(C1=C([H])N=C([H])N1C([H])([H])[H])C1=C([H])C(=C(C#N)C([H])=C1[H])C1=C(C([H])=C([H])C([H])=C1[H])C(F)(F)F)C([H])([H])[C@@]1([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]N(C(=O)C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])(C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H])[C@@]([H])(C1=C([H])C([H])=C(Cl)C([H])=C1[H])C([H])(F)F
[H]N([H])C1=NC(=C(C(=N1)N([H])[H])C1=C([H])C(N([H])\N=N/C([H])([H])[H])=C(Cl)C([H])=C1[H])C([H])([H])C([H])([H])[H]
[H]OC1=C(C(=O)OC([H])([H])[H])C([H])([H])N(C1=O)C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N=C(N([H])[H])N([H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[C@@]([H])(N([H])C(=O)C1=C([H])C([H])=C([H])C([H])=C1[H])P(=O)(OC1=C([H])C([H])=C([H])C([H])=C1[H])OC1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C([H])([H])C1=C([H])C(Cl)=C(Cl)C([H])=C1[H])C([H])([H])[C@]([H])(N([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C(=O)N1C([H])([H])C([H])([H])C2(C3=C(C([H])=C([H])C([H])=C3[H])N(C2([H])[H])S(=O)(=O)C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N(C(=O)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C1=C(C([H])=C2N(C3=C(C([H])=C([H])C([H])=C3[H])C2=C1C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H]
[H]O[C@]([H])(C([H])([H])OC1=C(C#N)C([H])=C([H])C([H])=C1[H])C([H])([H])N([H])C([H])([H])C([H])([H])N([H])C(=O)N([H])C1=C([H])N=C(OC([H])([H])C([H])([H])F)C([H])=C1[H]
[H]OC(=O)[C@@]1([H])C([H])([H])C([H])([H])[C@]([H])(N([H])C(=O)C([H])([H])C2=C([H])C(O[H])=C(O[H])C(O[H])=C2[H])C([H])([H])C1([H])[H]
[H]N(C1=NC(F)=NC(=N1)N([H])[C@]([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H])C([H])([H])C([H])([H])OC1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC1=C([H])C([H])=C(\C([H])=C(\[H])C2=C3\C(=N\N([H])C4=C([H])C([H])=C(C([H])=C4[H])S(=O)(=O)N([H])[H])\C(=O)N([H])C3=C([H])C([H])=C2[H])C([H])=C1[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])N1C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])[C@@]2([H])C3=C([H])C([H])=C([H])C(OC([H])([H])[H])=C3C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]C1=C(C([H])=C2C([H])=C3C(OC([H])([H])C([H])([H])C3([H])[H])=NC2=C1[H])C(=O)[C@]1([H])C([H])([H])C([H])([H])[C@]([H])(OC([H])([H])[H])C([H])([H])C1([H])[H]
[H]N1C2=C(C([H])=C([H])C([H])=C2[H])C2=C1C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C2([H])[H]
[H]N(\N=C1/C(=O)N([H])C2=C1C([H])=C([H])C([H])=C2[H])C(=O)C([H])([H])N(C1=C([H])C([H])=C(Cl)C([H])=C1[H])S(=O)(=O)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])C(=O)N([H])C([H])([H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H]
[H]O[C@@]([H])([C@@]([H])(N([H])C(=O)[C@]1([H])C([H])([H])N(C(=O)C1([H])[H])C([H])([H])C1=NC([H])=C([H])S1)C([H])([H])C1=C([H])C(F)=C([H])C(F)=C1[H])[C@]1([H])N([H])C([H])([H])[C@]([H])(OC([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C1([H])[H]
[H]C1=C([H])C(=C([H])C([H])=C1F)N1C([H])([H])C([H])([H])C([H])(C(=O)C([H])([H])C([H])([H])[C@@]([H])(OC2=C([H])C([H])=C(C([H])=C2[H])[N+]([O-])=O)C2=C([H])C([H])=C(F)C([H])=C2[H])C([H])([H])C1([H])[H]
[H]ON([H])C(=O)[C@]([H])(N(C([H])([H])C1=C([H])C2=C(OC([H])([H])O2)C([H])=C1[H])S(=O)(=O)C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=O)OC([H])([H])C([H])([H])[H]
[H]N([H])C1=NC2=C([H])C([H])=C([H])C([H])=C2N=C1\N=C(/[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
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[H]OC1=C([H])C(O[H])=C2C([H])=C(N([H])C2=C1[H])C(=O)N1C([H])([H])C([H])([H])C([H])(C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N(C(=O)C1=NC([H])=C(C#N)N1[H])C1=C(C([H])=C(C([H])=C1[H])C1([H])C([H])([H])C([H])([H])N(C(=O)C([H])([H])[H])C([H])([H])C1([H])[H])C1=C([H])N([H])C([H])([H])C([H])([H])C1([H])[H]
[H]OC([H])([H])[C@@](N([H])[H])(C([H])([H])OP(=O)(O[H])O[H])C([H])([H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C(OC2=C([H])C([H])=C([H])C([H])=C2[H])C([H])=C1[H]
[H]OC1=C(C(=O)N([H])C2=NC([H])=C([H])S2)C(=NC2=C(C([H])=C([H])C([H])=C12)C(F)(F)F)C([H])(Cl)Cl
[H]OC(=O)C1=C([H])C([H])=C(C([H])=C1[H])C1=NN(C2=C([H])C([H])=C(C#N)C([H])=C2[H])[C@@]([H])(C2=C([H])C([H])=C([H])O2)C1([H])[H]
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[H]N([H])C([H])([H])C1=C(C([H])=C([H])C(OC([H])([H])[H])=C1[H])N1N=C(C([H])=C1C(=O)N([H])C1=C([H])C([H])=C(C([H])=C1F)C1=C([H])C([H])=C([H])C([H])=C1S(=O)(=O)N([H])[H])C(F)(F)F
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[H]C1=NC([H])=C(C([H])=N1)C1=C([H])C([H])=C(C([H])=C1[H])C1=NN=C(N1C([H])([H])[H])C1(C2=C([H])C([H])=C(Cl)C([H])=C2[H])C([H])([H])C([H])([H])C1([H])[H]
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[H]N([H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])N=C2N([H])C([H])=C(C2=C1[H])C1=C([H])C(N([H])C(=O)N([H])C2=C([H])C([H])=C([H])C([H])=C2OC2=C([H])C([H])=C([H])C([H])=C2[H])=C([H])C([H])=C1[H]
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[H]N(C(=O)N([H])C([H])([H])C1(C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C1=C(C([H])=C([H])C([H])=C1C([H])(C([H])([H])[H])C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H]
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[H]O[C@@]([H])([C@@]([H])(N([H])C(=O)[C@]1([H])C([H])([H])N(C(=O)C1([H])[H])C([H])([H])C([H])([H])OC([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C1=C([H])C(F)=C([H])C(F)=C1[H])[C@]1([H])N([H])C([H])([H])[C@]([H])(OC([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C1([H])[H]
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[H]N([H])[C@]([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])N1C(=O)N(C(=O)N(C1=O)C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1OC([H])([H])[H])C1=C([H])C([H])=C([H])C(OC([H])([H])[H])=C1F
[H]N([H])C([H])([H])C([H])([H])[C@]([H])(OC1=C([H])C([H])=C(C([H])=C1[H])C(F)(F)F)C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C1=C([H])C(C2=C([H])C([H])=C(C([H])=C2[H])C([H])([H])[H])=C(C([H])=N1)[C@@]1([H])SC([H])([H])C(=O)N1C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H]
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[H]OC1=C([H])C(\C([H])=C(/[H])C2=C([H])C([H])=C([H])C(=C2[H])C(F)(F)F)=C([H])C(O[H])=C1C([H])([H])C(\[H])=C(/C([H])([H])[H])C([H])([H])C([H])([H])C([H])=C(C([H])([H])[H])C([H])([H])[H]
[H]OC1=C([H])C2=C(C([H])=C1[H])[C@]([H])(N(C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C2([H])[H])C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]OC1=C([H])C([H])=C([H])C([H])=C1N1C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])[C@@]([H])(O[H])C2=C(SC(=C2[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N([H])C(=O)C1=C([H])C2=C(OC3=C([H])C([H])=C(C([H])=C3[H])C([H])([H])OC([H])([H])C([H])([H])OC([H])([H])[H])C([H])=NC([H])=C2S1
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[H]N(C(=O)C1=C([H])C(Cl)=C([H])C([H])=C1N([H])C(=O)C1=C([H])C([H])=C(C([H])=C1[H])[S+]([O-])(=NC(=O)C([H])([H])N([H])C([H])([H])C([H])([H])[H])C([H])([H])[H])C1=NC([H])=C(Cl)C([H])=C1[H]
[H]C1=C([H])C(=C([H])C(=C1[H])C1=C([H])C(=O)C2=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C([H])=C2O1)N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H]
[H]N(C1=NC2=C([H])C([H])=C([H])C([H])=C2N2C([H])=NC([H])=C12)C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C1=C([H])C2=C(C([H])=C1OC([H])([H])C1([H])C([H])([H])C([H])([H])C1([H])[H])[C@]13C([H])([H])C([H])([H])N(C([H])([H])C4([H])C([H])([H])C([H])([H])C4([H])[H])[C@]([H])(C2=O)[C@]1([H])C([H])([H])C([H])([H])C([H])([H])C3([H])[H]
[H]N1C([H])=NC2=C(I)C(I)=C(I)C(I)=C12
[H]N1C2=C([H])C([H])=C(F)C([H])=C2C2=C1C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=N1)C2([H])[H]
[H]N(C(=O)C([H])([H])[H])C1=C([H])C2=C(C([H])=C([H])N2C2=NC3=C(C#N)C([H])=NN3C(N([H])C3([H])C([H])([H])OC3([H])[H])=C2[H])C([H])=C1[H]
[H]N(C(=O)N([H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])(C([H])([H])C2=C([H])C([H])=C(F)C([H])=C2[H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C(F)(F)F
[H]C1=C([H])C([H])=C(C([H])=C1[H])C1=NOC(=N1)C1=C(Cl)C([H])=C(C([H])=C1[H])C([H])([H])[H]
[H]C1=C([H])C([H])=C2C(=C1[H])N(C(=O)C2([H])[H])C1([H])C([H])([H])C([H])([H])N(C(=O)C2=C([H])C(OC([H])([H])[H])=C(C([H])=C2[H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]OC(=O)[C@]([H])(C1=C([H])C([H])=C(C(F)=C1[H])C1=C([H])C(OC([H])([H])C([H])([H])[H])=C([H])C([H])=C1[H])C([H])([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1C([H])([H])C([H])([H])C([H])(C([H])([H])C([H])([H])N(C(=O)C2=C([H])C([H])=C(C([H])=C2[H])S(=O)(=O)C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]OC(=O)C([H])([H])C([H])([H])C1=C([H])C2=C(C3=C([H])C([H])=C(C([H])=C3[H])C([H])([H])[H])C(=C(N=C2C([H])=C1[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])N([H])[H]
[H]OC(=O)C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C2=C(C([H])=C1[H])C([H])([H])C([H])([H])[C@]([H])(N([H])C([H])([H])[C@]([H])(O[H])C1=C([H])C([H])=C([H])N=C1[H])C2([H])[H]
[H]OC1=C([H])C([H])=C(Cl)C(=C1[H])C1=C([H])C(=C2N=C(N=NC2=C1[H])N([H])C1=C([H])C(OC([H])([H])C([H])([H])N2C([H])([H])C([H])([H])C([H])([H])C2([H])[H])=C([H])C([H])=C1[H])C([H])([H])[H]
[H]C1=C(N=NN1C1=C([H])C([H])=C(F)C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=N1
[H]C1=C([H])C([H])=C(C([H])=C1[H])C(=O)C1=C(C2=C([H])C([H])=C(C([H])=C2[H])S(=O)(=O)C([H])([H])[H])C(OC1=O)(C([H])([H])[H])C([H])([H])[H]
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[H]C1=C([H])C2=C([H])C([H])=C3C(=C2O1)C([H])([H])C([H])([H])C([H])([H])[C@@]3([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C([H])([H])C1=C([H])C([H])=C2OC([H])([H])OC2=C1[H]
[H]OC([H])([H])[C@]([H])(N([H])C(=O)C([H])([H])N([H])C(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]1([H])C(=O)N2C([H])([H])[C@]([H])(O[H])C([H])([H])[C@@]2([H])C(=O)N([H])[C@@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=O)C([H])([H])C1([H])[H])C([H])([H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=N[H])N([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])O[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=N[H])N([H])[H])C([H])([H])C([H])([H])C(=O)N([H])[H]
[H]N(C1=C([H])C([H])=C(C([H])=C1[H])C(F)(F)F)C1=NC(=NC2=C1C([H])([H])C([H])([H])N(C1=NC([H])=C([H])C([H])=C1C(F)(F)F)C([H])([H])C2([H])[H])N([H])C([H])([H])[C@@]1([H])N(C(=O)OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]OC(=O)C1=C([H])C(=C([H])C([H])=C1OC([H])([H])[H])C([H])([H])N1C([H])([H])C([H])([H])C([H])(C2=C([H])N(C3=C([H])C(F)=C([H])C([H])=C23)C([H])([H])C([H])([H])OC([H])([H])[H])C([H])([H])C1([H])[H]
[H]OC(=O)[C@@]([H])(C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(OC([H])([H])C([H])([H])C2=C(OC(=N2)C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])[H])N=C1[H]
C(CC1=CC=CC=C1)N1CCN(CC2=CC=C(C=C2)C2=NN=C3N2C2=CC=CN=C2NC2=C3C=CC=C2)CC1
[H]OP(=O)(O[H])C([H])([H])C([H])([H])[C@](N([H])[H])(C([H])([H])[H])C([H])([H])C([H])([H])C1=C([H])C([H])=C(OC([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])=C1[H]
[H]\C(=N/N(C1=NS(=O)(=O)C2=C([H])C([H])=C([H])C([H])=C12)C([H])([H])[H])C1=C([H])C([H])=NC([H])=C1[H]
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[H]OC1=C2C(=NN(C2=C2C([H])=C(C([H])=C([H])C2=N1)[N+]([O-])=O)C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)N([H])[H])C([H])([H])[H]
[H]C1=C(OC(=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])[N+]([O-])=O)C(=O)OC([H])([H])C1=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C(OC([H])([H])[H])=C1[H]
CC1=NC2=CC=C(C=C2N2C1=NN=C2C1=CC=CC=C1Cl)C(=O)NCCN1CCOCC1
[H]N([H])C1=NC(=C([H])C2=NC(=NN12)C1=C([H])C([H])=C([H])O1)N(C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C([H])C([H])=C(OC([H])([H])C([H])([H])OC([H])([H])[H])C([H])=C2[H])C([H])([H])C1([H])[H])C([H])([H])C1([H])C([H])([H])C1([H])[H]
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[H]OC1=C(C2=C(N=C3C4=C([H])C5=C(C(=O)N4C([H])([H])C3=C2[H])C([H])([H])OC(=O)[C@]5(O[H])C([H])([H])C([H])([H])[H])C([H])=C1[H])C([H])([H])N1C([H])([H])C1([H])[H]
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[H]N(C([H])([H])C([H])([H])C1=C([H])C([H])=[N+]([O-])C(=C1[H])C([H])([H])[H])C([H])([H])[C@]([H])(C1=C(N([H])C2=C([H])C([H])=C(C([H])=C12)C(C(=O)N1C([H])([H])[C@]2([H])C([H])([H])C([H])([H])[C@@]1([H])C([H])([H])C2([H])[H])(C([H])([H])[H])C([H])([H])[H])C1=C([H])C(=C([H])C(=C1[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])[H]
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[H]C1=C([H])C([H])=C(C(OC([H])([H])[H])=C1[H])C([H])([H])N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C(=O)C1=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]N(C(=O)C([H])([H])C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C(C2=C(S1)N(C([H])=C(C(=O)OC([H])([H])C([H])([H])[H])C2=O)C([H])([H])C1=C(F)C([H])=C([H])C([H])=C1F)C([H])([H])N(C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C1=C([H])C2=C(C([H])=C1OC([H])([H])[H])C(=O)C1=C(C([H])=C(C([H])=C1[H])C1=NN(N=N1)C([H])([H])[H])S2(=O)=O
[H]N([H])S(=O)(=O)C1=C([H])C(N([H])S(=O)(=O)C2=C([H])C([H])=C(N([H])C([H])([H])C3=C([H])C(=O)OC4=C3C([H])=C([H])C(Cl)=C4[H])C([H])=C2[H])=C([H])C([H])=C1[H]
[H]OC1(C2=C([H])C(=C([H])C([H])=C2[H])C(F)(F)F)C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C(C(=O)OC([H])([H])[H])(C2=C([H])C([H])=C([H])C([H])=C2[H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
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[H]N([H])S(=O)(=O)C1=C([H])C([H])=C(N([H])C(=O)C([H])([H])C2=C([H])C([H])=C([H])S2)C([H])=C1[H]
[H]N1C(=NC2=NC(=C([H])C([H])=C12)C(F)(F)F)N1C([H])([H])C([H])([H])N(C2=NC([H])=C([H])C([H])=C2C(F)(F)F)C([H])([H])C1([H])[H]
[H]N(C(=O)OC([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])[C@]([H])(C([H])=O)C([H])([H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H]
[H]C1=C([H])C2=C([H])C([H])=C([H])C(=C2C([H])=C1[H])C1(C([H])([H])N(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
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[H]N(C1=NC(=C([H])S1)C1=C([H])C([H])=NC([H])=C1[H])C1=NC([H])=C([H])C([H])=C1[H]
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[H]OC(=O)C(\[H])=N\O[C@]([H])(C1=C([H])C2=C([H])C([H])=C(OC([H])([H])C3=NC4=C([H])C([H])=C([H])C([H])=C4C([H])=C3[H])C([H])=C2C([H])=C1[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]OC1=C([H])C([H])=C2C3=C([H])C(O[H])=C(O[H])C([H])=C3N([H])C(=O)C2=C1O[H]
[H]N(C(=O)C([H])([H])[H])[C@@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])C1=C([H])C([H])=C(OC2=NC([H])([H])[C@@]([H])(OC([H])(C([H])([H])[H])C([H])([H])[H])N=C2[H])C([H])=C1[H]
[H]OC1=C([H])C(=C([H])C([H])=C1C([H])([H])N([H])[H])C([H])([H])C([H])([H])OC1=C([H])C(=C([H])C(OS(=O)(=O)C2=C([H])C(Cl)=C([H])C([H])=C2Cl)=C1[H])C([H])([H])[H]
[H]N([H])C1=NC(=C([H])C(=C1C#N)C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])C1=C([H])C([H])=C([H])O1
[H]N(C(=O)C1=C([H])C([H])=C(OC([H])([H])C2=C([H])C(=NC3=C([H])C([H])=C([H])C([H])=C23)C([H])([H])[H])C([H])=C1[H])C([H])([H])C1(C(=O)N([H])C(=O)N([H])C1=O)C1([H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H]
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[H]SC([H])([H])[C@]([H])(N([H])C(=O)C([H])([H])[H])C(=O)N([H])[C@]([H])(C(=O)N([H])[H])C([H])([H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H]
[H]N(C(=O)C1=C(N([H])C([H])=N1)C([H])([H])[H])[C@@]1([H])C([H])([H])[C@@]2([H])C([H])([H])C([H])([H])[C@]1(C([H])([H])S(=O)(=O)N1C([H])([H])C([H])([H])C3(C4=C([H])C([H])=C([H])C([H])=C4C([H])([H])C3([H])[H])C([H])([H])C1([H])[H])C2(C([H])([H])[H])C([H])([H])[H]
[H]N1C(=O)N([H])C2(C3=C(OC([H])([H])[H])C([H])=C([H])C(Cl)=C13)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H]
[H]N(C(=O)C1=C([H])C(N([H])C2=NC([H])=NN3C([H])=C(C(=O)C4=C([H])C([H])=C([H])N4C([H])([H])[H])C(=C23)C([H])([H])[H])=C(C([H])=C1[H])C([H])([H])[H])C1([H])C([H])([H])C1([H])[H]
[H]C1=C([H])C([H])=C(C(=O)C2=C([H])C(=C(F)C([H])=C2[H])[N+]([O-])=O)C(=C1[H])C(=O)OC(=O)C([H])([H])[H]
[H]N([H])C(=O)C1=C2N([H])C3=C(C([H])=C([H])C(=C3[H])C3=NN=C(C([H])=C3[H])N3C([H])([H])C([H])([H])S(=O)(=O)C([H])([H])C3([H])[H])C2=C(N=C1[H])N([H])[C@]([H])(C1([H])C([H])([H])C1([H])[H])C(F)(F)F
[H]N(C(=O)C([H])([H])SC1=NC(=NN1C(=O)C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C(=C([H])C([H])=C1[H])[N+]([O-])=O
[H]N(C([H])([H])[H])C([H])([H])C([H])([H])[C@]([H])(N1C2=C(C([H])=C([H])C([H])=C2[H])C2(C1=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
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[H]OC(=O)[C@@]([H])(N([H])S(=O)(=O)C1=C([H])C([H])=C([H])S1)C([H])([H])C1=C([H])C([H])=C(OC([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])C([H])([H])C([H])([H])N([H])C([H])([H])C2([H])[H])C([H])=C1[H]
NC1=NC(=NC2=CN(N=C12)C1=CC=CC=C1)C1=CC=CC=C1
[H]N(C([H])=O)C1=C([H])C2=C(C([H])=C1Cl)C(=O)N(C(=C(O2)C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H]
[H]OC1=C(C(=O)N([H])C([H])([H])[C@@]2([H])N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C2([H])[H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C([H])=C1C([H])([H])C([H])([H])F
[H]OC(=O)C1=C([H])C(=C([H])C(=C1[H])C(=O)N([H])[H])C1=C([H])C([H])=C([H])C(=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H]
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[H]OC(=O)C([H])([H])[C@]([H])(N([H])C(=O)[C@]([H])(N1C([H])=C([H])C([H])=C(N([H])C(=O)C2=C([H])C3=C([H])C([H])=C([H])C([H])=C3C([H])=C2[H])C1=O)C([H])([H])C([H])([H])[H])C(=O)C([H])([H])N([H])C(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]N(C(=O)OC([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C2=C(N1[H])C(=O)N(C(=O)N2C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C([H])O1
[H]N(C(=O)N1C([H])([H])C([H])([H])N2C(=O)N(C(=O)[C@@]2([H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C(C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C1=C([H])C([H])=C([H])C(=C1[H])N(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])[C@]1(C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])OC(C([H])([H])[H])(C([H])([H])[H])C1([H])[H]
[H]OC(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N1C(=O)C([H])([H])C([H])([H])[C@]1([H])C(\[H])=C(/[H])[C@]([H])(O[H])C1=C([H])C(OC2=C([H])C([H])=C([H])C([H])=C2[H])=C([H])C([H])=C1[H]
[H]C1=C(N(N=C1C(F)(F)F)C1=C([H])C([H])=C(Cl)C([H])=C1[H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]N=C(N(C([H])([H])[H])C([H])([H])C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C(=O)N1C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])S(=O)(=O)C1=C([H])C2=C(N1[H])C([H])=C([H])C(Cl)=C2[H]
[H]N([H])C(=O)C1=C([H])C([H])=C2C(=C1[H])N(C([H])=C2[C@@]([H])(C(=O)N([H])S(=O)(=O)C1=C([H])C([H])=C(C([H])=C1OC([H])([H])C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C2OC([H])([H])OC2=C1[H])C([H])([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])[C@@]1([H])C2=C([H])C([H])=C(OC([H])([H])C([H])([H])C([H])([H])N3C([H])([H])C([H])([H])C([H])([H])C([H])([H])C3([H])[H])C([H])=C2[C@@]2([H])N(C([H])([H])C([H])([H])C2([H])[H])C1([H])[H]
[H]OC(=O)C([H])([H])[C@]([H])(N([H])C(=O)C([H])([H])N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)C([H])([H])N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)C([H])([H])N([H])[H])C([H])([H])C([H])([H])C(=O)N([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=N[H])N([H])[H])C([H])([H])C([H])([H])C(=O)N([H])[H])C([H])([H])C([H])([H])SC([H])([H])[H])C([H])([H])[H])[C@@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])[H])[C@@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])[H])C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)O[H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=N[H])N([H])[H])C([H])([H])C(=O)N([H])[H])[C@@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])[H])C([H])([H])C(=O)O[H]
[H]C1=C([H])C([H])=C(C(Cl)=C1[H])C1=C([H])C([H])=C(C#N)C(=C1[H])C(F)(F)F
[H]C1=C([H])C(=C([H])C([H])=C1OC(F)(F)F)C(=N\OC([H])([H])C([H])([H])[H])\C1([H])C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])C1(C([H])([H])[H])C([H])([H])C([H])([H])N(C(=O)C2=C([N+]([O-])=C([H])C([H])=C2C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]OC(=O)C1=C([H])N([H])C([H])=C(C(=O)OC([H])([H])C(\[H])=C(/[H])C2=C([H])C([H])=C([H])C([H])=C2[H])[C@]1([H])C1=C([H])C([H])=C([H])C(Cl)=C1[H]
[H]OC([H])([H])[C@]1([H])C([H])([H])C2=C([H])C([H])=C([H])C(OC3=C([H])C([H])=C([H])C(OS(=O)(=O)C([H])([H])C([H])([H])C([H])([H])C(F)(F)F)=C3[H])=C2C1([H])[H]
[H]N1[C@@]2([H])C([H])([H])C([H])([H])[C@]1([H])C([H])([H])[C@]([H])(OC(=O)C1=C([H])C([H])=C([H])C([H])=C1[H])C2([H])[H]
[H]N(C([H])([H])[H])C([H])([H])C1=C(OC2=C(Cl)C([H])=C([H])C([H])=C2[H])C([H])=C(N=C1[H])C([H])([H])[H]
[H]OC(=O)C([H])([H])C([H])([H])[C@]([H])(N([H])C(=O)C1=C([H])C([H])=C(C([H])=C1[H])N(C([H])([H])C([H])=C([H])[H])C([H])([H])[C@@]1([H])N(C2=C(N=C(N=C2C([H])([H])C1([H])[H])N([H])[H])N([H])[H])C([H])([H])C([H])=C([H])[H])C(=O)O[H]
[H]C1=NC2=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C([H])=C2C([H])=C1OC1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(C(=O)C1=C([H])N(C(=C([H])C1=O)C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])[C@]12C([H])([H])[C@@]3([H])C([H])([H])[C@]([H])(C([H])([H])[C@]([H])(C3([H])[H])C1([H])[H])C2([H])[H]
[H]C1=C([H])C([H])=C(O1)C1=C([H])C(=O)C([H])([H])C2(O1)C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C2([H])[H]
[H]N([H])S(=O)(=O)[C@@]12C([H])([H])[C@@]3([H])C([H])([H])[C@@]([H])(C1([H])[H])[C@]([H])(N([H])C(=O)C(OC1=C([H])C([H])=C([H])C([H])=C1Cl)(C([H])([H])[H])C([H])([H])[H])[C@]([H])(C3([H])[H])C2([H])[H]
[H]OC1=C([H])C([H])=C([H])C2=C1N([H])C1=C2C2=C(C(=O)N(N([H])C(=O)N([H])C3=C([H])C([H])=C([H])C([H])=C3[H])C2=O)C2=C1N(C1=C2C([H])=C([H])C([H])=C1O[H])[C@]1([H])O[C@]([H])(C([H])([H])O[H])[C@@]([H])(O[H])[C@@]([H])(O[H])[C@]1([H])O[H]
[H]OC(=O)[C@@]1([H])[C@@]([H])(N([H])C(=O)[C@@]2([H])N(C([H])([H])C([H])([H])C2([H])[H])S(=O)(=O)C2=C([H])C(Cl)=C([H])C(Cl)=C2[H])[C@]2([H])C([H])=C([H])[C@@]1([H])C2([H])[H]
[H]OC1=C([H])C2=C(C([H])=C1[H])C(=O)C1=C(O2)C2=C(O1)C(Br)=C([H])C(O[H])=C2[H]
[H]N(C(=O)N(C([H])([H])[H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])C2=C([H])N([H])C3=C([H])C([H])=C(C([H])=C23)N2C([H])=NN=C2[H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N=C(N([H])C1=C([H])C([H])=C2SC(=NC2=C1[H])N([H])C([H])([H])C([H])([H])[C@@]1([H])N(C([H])([H])[H])C([H])([H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C([H])S1
[H]N1C([H])([H])C([H])([H])C(=C(C2=C([H])C([H])=C(C([H])=C2[H])C(=O)N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H])C2=C([H])C(=C([H])C([H])=C2[H])C(F)(F)F)C([H])([H])C1([H])[H]
[H]N1C(=O)C2=C([H])C([H])=C([H])C3=C2[C@@]([H])(N(C(=O)C([H])([H])N2C([H])([H])C([H])([H])N(C4=C([H])C([H])=C([H])C([H])=C4[H])C([H])([H])C2([H])[H])C([H])([H])C3([H])[H])C1([H])[H]
CCC(=O)N(C1CCN(CCN2C(=O)N(C(C)=C)C3=C2C=CC=C3)CC1)C1=C(Cl)C=CC(Cl)=C1
[H]N(C1=NC2=C([H])C(N([H])S(=O)(=O)C3=C([H])C([H])=C([H])C([H])=C3[H])=C([H])C([H])=C2O1)C1([H])C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C(OC([H])([H])[H])C(OC([H])([H])C([H])([H])[H])=C2[H])C([H])([H])C1([H])[H]
[H]OC1=C([H])C2=C(C([H])=C1[H])C1=C(N2[H])C2=C(C3=C(C([H])=C(O[H])C([H])=C3[H])N2O[C@]2([H])O[C@]([H])(C([H])([H])O[H])[C@@]([H])(O[H])[C@]([H])(O[H])[C@@]2([H])O[H])C2=C1C(=O)N(N([H])C([H])([H])C1=C(C([H])=C([H])C([H])=N1)C([H])([H])O[H])C2=O
[H]N(C(=O)C([H])([H])C([H])([H])C([H])([H])N(C1=NS(=O)(=O)C2=C([H])C([H])=C([H])C([H])=C12)C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]N([H])C1=C([H])C([H])=C(C([H])=C1N([H])C(=O)C1=C([H])C([H])=C(N=C1[H])N1C([H])([H])C([H])([H])[C@@]2(C([H])([H])N(C(=O)C([H])([H])[H])C([H])([H])C2([H])[H])C1([H])[H])C1=C([H])C([H])=C([H])S1
[H]O[C@@]([H])(C([H])([H])N1C([H])([H])[C@@]2([H])[C@@]([H])(C1([H])[H])[C@@]2(C1=C([H])C(N([H])S(=O)(=O)C([H])([H])[H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC1=C(C(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C(=O)OC(=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]N(C(=O)[C@]1([H])C2=C(C([H])=C1C([H])([H])[H])C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C2(C3=C([H])C([H])=C([H])C([H])=C3C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]OC(=O)C1=C([H])SC(SC([H])([H])C([H])([H])N2C(=O)C([H])([H])C([H])([H])[C@]2([H])C(\[H])=C(/[H])[C@@]([H])(O[H])C([H])([H])C2=C([H])C([H])=C([H])C(=C2[H])C([H])([H])[H])=N1
[H]N1N(C2=C([H])C(F)=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C([H])([H])C1=O
[H]N(C(=O)N1C([H])([H])C([H])([H])C([H])(N2C(=O)N([H])C3=C2C([H])=C([H])C([H])=N3)C([H])([H])C1([H])[H])C1=C([H])C(=C([H])N(C1=O)C([H])([H])C(F)(F)F)C1=C([H])C([H])=C([H])C(F)=C1F
ClC1=CN=C(NC(=O)[C@H](CC2CCCCC2)N2C=NC3=C(C=CC(=C3)S(=O)(=O)C3CCCC3)C2=O)S1
[H]OC(=O)C(=O)[C@]1([H])N(C([H])([H])C2=C([H])C([H])=C(C([H])=C2C1([H])[H])[N+]([O-])=O)S(=O)(=O)C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]OC([H])([H])[C@@]1([H])O[C@@]([H])(N2C([H])=NC3=C(N=C([H])N=C23)N([H])C([H])([H])[C@@]2(O[H])C3=C(C([H])=C([H])C([H])=C3[H])C([H])([H])C2([H])[H])[C@]([H])(O[H])[C@]1([H])O[H]
[H]N([H])C([H])([H])[C@@]([H])(C(=O)N(C([H])([H])C1=C([H])C([H])=C([H])C(Cl)=C1Cl)C1([H])C([H])([H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])OC1=C(F)C([H])=C([H])C(F)=C1Cl
[H]N1C2=C([H])C([H])=C(C([H])=C2C(OC([H])([H])C1=O)(C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]N(C(=O)C1([H])C([H])([H])C(F)(F)C1([H])[H])[C@]([H])(C1=C([H])C([H])=C([H])C(F)=C1[H])C([H])([H])C([H])([H])N1C([H])([H])[C@@]2([H])C([H])([H])[C@]([H])(N3C(=NN=C3C([H])([H])[H])C([H])([H])[H])C([H])([H])[C@@]2([H])C1([H])[H]
[H]N([H])C1=NC2=C(C([H])=N1)C([H])=C(C(=N2)N([H])C(=O)N([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N([H])C([H])([H])[C@]1([H])C([H])([H])[C@@]1(C(=O)N(C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)C(\[H])=C(/[H])C1=C([H])C([H])=C(OC([H])([H])C([H])([H])C([H])([H])C#N)C([H])=C1OC1=NC([H])=C(C([H])=C1Cl)C(F)(F)F)S(=O)(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]C1=C([H])C(=C([H])C([H])=C1I)[C@]1([H])C([H])([H])[C@]2([H])N(C([H])([H])[H])[C@@]([H])(C([H])([H])C2([H])[H])[C@@]1([H])C(=O)N(OC([H])([H])[H])C([H])([H])[H]
[H]N(N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C(=O)C1=NN(C(=C1C([H])([H])[H])C1=C([H])C([H])=C(I)C([H])=C1[H])C1=C([H])C([H])=C(Cl)C([H])=C1Cl
[H]C1=C([H])C(C2=NN=C(SC([H])([H])C([H])([H])N3C([H])([H])C([H])([H])C4=C([H])C5=C(OC(=N5)C(F)(F)F)C(=C4C([H])([H])C3([H])[H])C([H])([H])[H])N2C([H])([H])[H])=C2C([H])=C([H])C(=NC2=C1[H])C([H])([H])[H]
[H]OC([H])([H])[C@@]([H])(C([H])([H])C1=C([H])C(=C([H])C([H])=C1[H])C(=N[H])N([H])[H])[C@@]([H])(N([H])C(=O)C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C(\[H])=C(/[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
CC1=CN=C(CNCC2(F)CCN(CC2)C(=O)C2=CC=CO2)C=C1
[H]OC1(C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C2=C([H])N([H])C3=C([H])C([H])=C(F)C([H])=C23)C([H])([H])C1([H])[H])[C@@]([H])([S@+]([O-])C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C1=NC2=C(C([H])=NC3=C2C([H])=C([H])C([H])=C3[H])C(=O)N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C([H])C([H])=C([H])C(=C2[H])C(F)(F)F)C([H])([H])C1([H])[H]
[H]N([H])C1=NC(C2=C([H])N([H])C3=C(Br)C([H])=C([H])C([H])=C23)=C(C([H])=N1)C1=C([H])C([H])=C(N([H])C(=O)C([H])([H])[H])C([H])=C1[H]
[H]OC(=O)C([H])([H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1OC([H])([H])C([H])([H])N([H])C(=O)C1=C([H])C([H])=C(OC2([H])C([H])([H])C([H])([H])N(C(=N[H])C([H])([H])[H])C([H])([H])C2([H])[H])C([H])=C1[H])C(=N[H])N([H])[H]
[H]N(C(=O)C([H])([H])C([H])([H])C1=NC(=NO1)C1=C(Cl)C([H])=C(F)C([H])=C1[H])C1=C([H])C([H])=C(N=C1[H])C(F)(F)F
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[H]N(C([S-])=S)C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
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[H]N1C(=O)N(C2=C(N=C(SC3=C([H])C([H])=C(F)C([H])=C3[H])C([H])=C2[H])C1([H])[H])C1=C(Cl)C([H])=C(C([H])=C1Cl)C(F)(F)F
[H]N(C(=O)OC([H])([H])[H])C([H])([H])C([H])([H])O[C@@]([H])(C1=C(F)C([H])=C([H])C(F)=C1[H])[C@@]1([H])C([H])([H])N(C(=O)N([H])[C@]([H])(C([H])([H])N([H])C([H])([H])[H])C([H])([H])C2([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(C(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C(OC([H])([H])[H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H])[C@]1([H])C2=C([H])C([H])=C(OC([H])([H])[H])C([H])=C2C([H])([H])C([H])([H])C1([H])[H]
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[H]OC(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1=C([H])SC(=C1[H])C([H])([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C(O[H])C([H])=C1[H]
[H]C1=C([H])C(=NC(=C1[H])C([H])([H])[H])C#CC1=C([H])C([H])=C([H])C(OC(=O)C([H])([H])C([H])([H])C([H])([H])Br)=C1[H]
[H]N(C(=O)C(\[H])=C(/[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])C([H])(C1=C([H])C([H])=C([H])C([H])=C1OC([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1OC([H])([H])[H]
[H]N(C(=O)C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C1=C(C#N)C2=C(S1)C([H])([H])C([H])([H])C2([H])[H]
[H]C1=NC([H])=C(N=C1[H])C([H])([H])C([H])([H])SC1=C([H])C([H])=C2C3=C(C(=O)OC([H])([H])C([H])([H])[H])C(=O)N=C3C3=C2C1=C([H])C([H])=C3[H]
[H]OC(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])OC1=NC(=C([H])C(=C1[H])C1=C([H])C([H])=C([H])C([H])=C1F)C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)N(C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C(=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N([H])C(=NC1=NC([H])=C([H])C2=C([H])C([H])=C(OC([H])([H])[H])C([H])=C12)N([H])[H]
[H]N=C(N([H])[H])C1=C([H])C([H])=C([H])C(=C1[H])N1N=C(C([H])=C1C(=O)N([H])C1=C([H])C([H])=C(C([H])=C1[H])N1C([H])=NC2=C1C([H])=C([H])C([H])=C2[H])C([H])([H])N1C([H])=NC([H])=C1[H]
[H]N1C([H])=C(C2=C([H])C([H])=C([H])N=C12)C([H])([H])N1C([H])([H])C([H])([H])C([H])(C([H])([H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N(C(=O)N([H])C1=C([H])C([H])=NC([H])=C1[H])C1=NC2=NN(C([H])=C2C2=NC(=NN12)C1=C([H])C([H])=C([H])O1)C([H])([H])C([H])([H])OC([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N1C([H])([H])C([H])([H])N(C2=C([H])C(=O)N(C(=N2)C([H])([H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])[H])[C@]([H])(C([H])([H])[H])C1([H])[H]
[H]N([H])C1=NC2=C(C([H])=NN2C([H])([H])C([H])([H])N2C([H])([H])C3=C(N=C([H])C(OC([H])([H])C([H])([H])OC([H])([H])[H])=C3[H])C([H])([H])C2([H])[H])C2=NC(=NN12)C1=C([H])C([H])=C([H])O1
[H]N(C(=O)C([H])([H])C([H])([H])[C@]([H])(N([H])C(=O)OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C(=O)OC([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
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[H]N1C(=O)C([H])=C([H])C2=C1C([H])=C(C([H])=C2[H])C1=NN=C(S1)N1C([H])([H])C([H])([H])C([H])(N2C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]N([H])[C@@]1([H])C([H])([H])C2=C(N([H])C3=NC([H])=C(O3)C3=C([H])C([H])=C(C([H])=C3[H])C(F)(F)F)C([H])=C([H])C([H])=C2C([H])([H])C1([H])[H]
[H]N=C(N([H])[H])C1=C([H])C([H])=C(OC([H])([H])C([H])([H])OC2=C([H])C([H])=C(C([H])=C2[H])C2=NC3=C([H])C(=C([H])C([H])=C3N2[H])C(=N[H])N([H])[H])C([H])=C1[H]
[H]N(C(=O)C1=C([H])N(C2=C(C([H])=NC([H])=C2[H])C1=O)C([H])([H])[H])C1=C([H])C([H])=C(C2=NC([H])=C([H])C([H])=C2[H])C(=C1[H])C(F)(F)F
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[H]C1=C([H])C(=C([H])C2=C1OC([H])([H])O2)C1=NN=C(O1)SC([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C(C#N)C([H])=C1[H]
[H]OC1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N(C(=O)N([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C(O[H])C(=C([H])C(=C1[H])C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)N1C([H])([H])[C@@]([H])(C([H])=C2C3=C([H])C([H])=C([H])C4=C3C(=C([H])N4[H])C([H])([H])[C@@]12[H])C(=O)N1C([H])([H])C([H])([H])N([H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C([H])C([H])=C([H])C3=C2OC([H])([H])C([H])([H])O3)C([H])([H])C1([H])[H]
NC1=NC(=CC=N1)N1C=CC2=C1C=C(N=C2)C#N
[H]N=C(N([H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C(F)(F)F)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C1=C([H])N([H])C([H])=N1
[H]N([H])[C@@]1([H])C([H])([H])N(C2=NC3=C(C([H])=C([H])C([H])=C3Cl)C(=O)N2C([H])([H])C2=C(C#N)C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C1([H])[H]
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[H]N(C(=O)C(\[H])=C(/[H])C([H])=C(C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])N=C([H])C([H])=C1[H]
[H]N(C(=O)C([H])([H])N1SC2=C(C1=O)C(=C([H])C(=N2)C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]C1=C([H])C(=C([H])C([H])=C1C(=O)N1C([H])([H])C([H])([H])SC([H])([H])C1([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N(C(=O)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C2=C(C([H])=C1[H])C1=NC3=C([H])C([H])=C(C([H])=C3C(C([O-])=O)=C1C([H])([H])C2([H])[H])C(F)(F)F
[H]N([H])C(=O)C1=C(N([H])C2=C([H])C(=C(C([H])=C2[H])C([H])([H])[H])C([H])([H])[H])C2=C(N=C1[H])C([H])=C(C([H])=C2[H])C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)C([H])([H])[H]
[H]OC1=C2O[C@@]3([H])C4=C(C([H])=C([H])C([H])=N4)C([H])([H])[C@@]4([H])[C@]5([H])N(C([H])([H])[H])C([H])([H])C([H])([H])[C@]34C2=C(C([H])=C1[H])C5([H])[H]
[H]OC([H])([H])C1=C([H])N2C3=C1C([H])=C([H])C([H])=C3C(=O)N([H])C([H])([H])C2([H])[H]
[H]OC1=C([H])C([H])=C2C([H])=C(N(C2=C1[H])C([H])([H])[H])C(=O)N1C([H])([H])C([H])([H])C([H])(C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C([H])S1)[C@@]1([H])C([H])([H])C([H])([H])[C@]([H])(C([H])([H])C([H])([H])N2C([H])([H])C([H])([H])N(C3=C([H])C([H])=C(Cl)C([H])=C3[H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]C1=C([H])C2=C(O[C@]3([H])C([H])([H])OC4=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C([H])=C4[C@]3([H])C2=O)C2=C1O[C@]([H])(C2([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]OC(=O)[C@@]([H])(N([H])C(=O)C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)N([H])[H])C([H])([H])C(=O)N([H])[H]
[H]OC([H])([H])[C@@]1([H])OC(=O)[C@@]([H])(N(C2=C(C([H])=C(C([H])=C2[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C1([H])[H])C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C(SC([H])=C1[H])C(=O)OC([H])(C([H])([H])[H])C([H])([H])[H]
[H]OC1=NC([H])=C([H])C([H])=C1S(=O)(=O)N([H])[C@@]1([H])C([H])([H])N2C(=O)N(C3=C([H])C([H])=C(OC(F)(F)F)C([H])=C3[H])C([H])([H])[C@]2([H])C1([H])[H]
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[H]N(C1=C([H])C([H])=C(F)C([H])=C1[H])C1=NC(=NC2=C1C([H])=NN2C([H])([H])[H])N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]C1=C(SC(=C1[H])C(=O)C(F)(F)F)C(=O)N1C([H])([H])C([H])([H])N(C2=C([H])C([H])=C([H])C(OC([H])([H])[H])=C2[H])C([H])([H])C1([H])[H]
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[H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])S(F)(=O)=O
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[H]N([H])C(=NC([H])([H])C([H])([H])C([H])([H])[C@]([H])(N([H])S(=O)(=O)C1=C([H])C(=C([H])C([H])=C1[H])C(C1=C([H])C([H])=C([H])C([H])=C1[H])(C([H])([H])[H])C([H])([H])[H])C(=O)N1C([H])([H])C2=C(C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H])N([H])[H]
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[H]OC(=O)C([H])([H])C([H])([H])C(=O)N1C([H])([H])C([H])([H])C2(C([H])([H])N(C(=O)C2([H])[H])C2=C([H])C([H])=C(C([H])=C2[H])C(=N[H])N([H])[H])C([H])([H])C1([H])[H]
[H]OC(=O)C([H])([H])C([H])([H])[C@]([H])(C(=O)N1C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C(=O)O[H])C([H])([H])[H]
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[H]OC1=NC(=NC2=C1N([H])C(N([H])[H])=C2C([H])([H])C1=C([H])C([H])=C([H])O1)N([H])[H]
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[H]C([H])([H])N1C(=O)C([H])([H])C([H])([H])[C@]2(C([H])([H])[H])[C@]1([H])C([H])([H])C([H])([H])[C@]1([H])[C@@]3([H])C([H])([H])C([H])([H])[C@]4(OC(=O)C([H])([H])C4([H])[H])[C@@]3(C([H])([H])[H])C([H])([H])C([H])([H])[C@@]21[H]
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[H]N1C([H])([H])C([H])([H])C2(C1([H])[H])C([H])([H])C([H])([H])N(C1=C([H])C([H])=C3N=NN(C3=N1)C1=C([H])C([H])=C([H])C(OC(F)(F)F)=C1[H])C([H])([H])C2([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C([H])C([H])=C1C1=C([H])C([H])=C(OC([H])(C([H])([H])[H])C([H])([H])[H])C([H])=C1[H])C1=NC2=C([H])C([H])=C(C([H])=C2C([H])=C1[H])C(=O)N([H])[C@]([H])(C(=O)N([H])C([H])([H])C1=C([H])C([H])=C(F)C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]O[C@@]1(C#CC([H])([H])OC([H])([H])[H])C([H])([H])C([H])([H])[C@@]2([H])[C@]3([H])OC([H])([H])C4=C([H])C(=O)C([H])([H])C([H])([H])C4=C3[C@](C3=C([H])C([H])=C(C([H])=C3[H])N(C([H])([H])[H])C([H])([H])[H])(C([H])([H])[H])C([H])([H])[C@]12C([H])([H])[H]
[H]OC(=O)C([H])([H])[C@@]([H])(C#C[H])N([H])C(=O)C1=C([H])C2=C(C([H])=C1[H])C([H])([H])N(C2=O)C([H])([H])C([H])([H])C1=C([H])C(=NC([H])=C1[H])N([H])[H]
[H]OC(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C(\[H])=C(\[H])C([H])([H])[C@]1([H])[C@]([H])(OC([H])([H])[C@]1([H])O[H])C(\[H])=C(/[H])[C@@]([H])(O[H])C([H])([H])OC1=C([H])C(=C([H])C([H])=C1[H])C(F)(F)F
[H]N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C1=C([H])C([H])=C(OC([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])=C1[H]
[H]N(C(=S)N([H])[C@]1([H])C2=C(C(OC([H])([H])[H])=C(N([H])S(=O)(=O)C([H])([H])[H])C([H])=C2[H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]OC1=C(O[H])C([H])=C(\C([H])=C(/C#N)C(N([H])[H])=C(C#N)C#N)C([H])=C1[H]
[H]N(C(=O)C1=C([H])C(Cl)=C([H])C(=C1[H])C([H])([H])[H])C1=C([H])N=C2C([H])=C([H])C([H])=C([H])C2=C1[H]
[H]N=C(N([H])[H])C1=C([H])C([H])=C([H])C(=C1[H])C([H])([H])[C@@]([H])(N([H])S(=O)(=O)C1=C(C([H])=C(C([H])=C1C([H])(C([H])([H])[H])C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])C(=O)N1C([H])([H])C([H])([H])N(C(=O)OC([H])([H])[H])C([H])([H])C1([H])[H]
[H]N(C(=O)C([H])([H])C([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C(=C([H])C(=C1[H])C(F)(F)F)C(F)(F)F
[H]N1C2=C(N=C1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C(=O)N(C1=N[C@@]([H])(C([H])([H])N21)C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H]
[H]O\C(C(=O)OC([H])([H])[H])=C1/C(=O)N([H])C2=C([H])C([H])=C([H])C([H])=C12
COC1=CC=C(C=C1C1=CC(NC2=CC(OC)=C(C=C2)N2CCOCC2)=NC=C1)C#N
[H]N([C@@]1([H])C(=O)N([H])[C@@](C2=C([H])C([H])=C([H])C([H])=C2[H])(C([H])([H])O[C@@]([H])(C2=C([H])C(=C([H])C(=C2[H])C(F)(F)F)C(F)(F)F)C([H])([H])[H])C1([H])[H])S(=O)(=O)C([H])([H])[H]
[H]OC(=O)C1=C([H])C([H])=C(C([H])=C1[H])C1(N([H])C(=O)C2=C(SC(=C2C([H])([H])C2=C([H])C([H])=C(C([H])=C2[H])C(F)(F)F)C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]OC1=C([H])C(=C([H])C([H])=C1[H])N1C([H])([H])C([H])([H])C2=C(C([H])=C([H])C(O[H])=C2[H])[C@@]1([H])C1=C([H])C([H])=C(C([H])=C1[H])N1C([H])([H])C([H])([H])N(C([H])([H])C2([H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]N(C1=C([H])C(F)=C([H])C(F)=C1[H])C([H])([H])C1=C([H])N=C([H])N1[H]
[H]OC(=O)C([H])([H])N([H])C([H])([H])C([H])([H])N([H])C([H])([H])C(=O)N([H])C1=C(F)C([H])=C(C([H])=C1[H])S(=O)(=O)N([H])[H]
[H]OC1=C2N=C([H])N(C2=NC(=N1)N([H])[H])C([H])([H])C1=C([H])C(OC([H])([H])P(=O)(O[H])O[H])=C([H])C([H])=C1[H]
[H]N(C(=O)C1=NOC(=C1[H])C1=C([H])C([H])=C([H])S1)C1=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]OC1=C([H])C(O[H])=C(C([H])=C1Cl)C1=NN([H])C([H])=C1C(=O)N([H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)N([H])[H]
[H]OC(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]1([H])N(C(=O)[C@@]([H])(N([H])[H])C([H])([H])C([H])([H])C([H])([H])\N=C(\N([H])[H])N([H])C(=O)[C@@]([H])(N([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])C([H])([H])[H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C(O[H])C([H])=C1[H])[C@@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]OC(=O)C1=C(C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1C(=O)C2(N=C1C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H]
[H]N1N=NC(=N1)C1=C(C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1C(=O)N(N=C1C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
NC(=O)N1CCC2=C(C1)C(=NN2CCCN1CCCCC1)C1=CC(C#CC2=CC=C(CNCC3=CC=C(Cl)C=C3)C=C2)=C(Cl)C=C1
[H]N(\C(=N/C(=O)C1=C([H])C([H])=C(OC([H])([H])[H])C(OC([H])([H])[H])=C1[H])N([H])[C@]1([H])C(=O)N(C([H])([H])C(=O)N2C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C([H])C(=C1[H])C([H])([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1C([H])([H])C2=C(C3=C([H])C([H])=C(OC([H])([H])[H])C([H])=C3OC2=O)C([H])([H])C1([H])[H]
[H]N([H])N([H])C(=O)C(=N\N([H])C1=C(Cl)C([H])=C([H])C([H])=C1Cl)\C#N
[H]N([H])C(=O)C1=NN(C2=C1C([H])([H])C([H])([H])C1=C([H])C([H])=C(N([H])C(=O)C3=C(Cl)C([H])=NC(=C3[H])N3C([H])([H])C([H])([H])N(C([H])([H])C4=C([H])N(N=C4[H])C([H])([H])C(=O)N([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C3([H])[H])C([H])=C21)C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]N1[C@@]2([H])C([H])([H])C([H])([H])[C@]1([H])C([H])([H])[C@@](OC([H])([H])C1=C([H])C([H])=C(Cl)C([H])=C1[H])(C1=C([H])C([H])=C(Cl)C(Cl)=C1[H])C2([H])[H]
[H]OC1(C2=C([H])C([H])=C(Cl)C([H])=C2[H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])N([H])S(=O)(=O)C2=C([H])C([H])=C([H])S2)C([H])([H])C1([H])[H]
[H]C1=C([H])C(=NC(=C1[H])N(C(=O)C([H])([H])N(C1=C([H])C(=C([H])C([H])=C1Cl)N(C([H])([H])[H])C([H])([H])[H])S(=O)(=O)C1=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C([H])=C1[H])C([H])([H])C([H])([H])[H])C([H])([H])[H]
[H]C1=C(C2=C(OC([H])([H])[H])C([H])=C(F)C(=C2[H])C([H])(C([H])([H])[H])C([H])([H])[H])C(=C([H])C(=C1[H])S(=O)(=O)C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])N1C(=O)O[C@]([H])(C2=C([H])C(=C([H])C(=C2[H])C(F)(F)F)C(F)(F)F)[C@]1([H])C([H])([H])[H]
[H]OC1=C2N=C([H])N(C2=NC(=N1)N([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1\C([H])=C(/[H])P([O-])([O-])=O
[H]OC(=O)C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C([H])C3=C([H])C([H])=C([H])C([H])=C3C([H])([H])N3C(Cl)=C([H])N=C23)C([H])([H])C1([H])[H]
[H]N(C(=O)[C@@]([H])(C([H])([H])C(=O)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])[C@]([H])(C([H])([H])N([H])C1=C([H])C([H])=C(OC(F)(F)F)C([H])=C1[H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C1=NC(=C([H])N=C1C([H])([H])[H])C(=O)N1C([H])([H])[C@@]([H])(O[C@@]([H])(C2=C([H])C(=C([H])C(=C2[H])C(F)(F)F)C(F)(F)F)C([H])([H])[H])[C@]([H])(C2=C([H])C([H])=C(F)C([H])=C2[H])C1([H])[H]
[H]N(C1=C([H])C([H])=C(Cl)C([H])=C1[H])S(=O)(=O)C1=C([H])C([H])=C(C([H])=C1[H])C(=O)C([H])([H])SC(=S)SC([H])([H])C([H])([H])[H]
[H]OC(=O)[C@]1([H])N(C([H])([H])C2=C([H])C3=C(N=C(O[H])C(O[H])=N3)C([H])=C2Br)C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N1C(=O)[C@]2(N(C(=O)[C@]1([H])C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C(OC3=C([H])C([H])=C(OC([H])([H])[H])C([H])=C3[H])=C1[H])C([H])([H])C2([H])[H]
[H]N1N(C(=O)\C(=C(\[H])C2=C([H])C([H])=C(OC([H])([H])C3=C([H])C([H])=C([H])C([H])=C3[H])C([H])=C2[H])C1=O)C1=C([H])C([H])=C(C(Cl)=C1[H])C([H])([H])[H]
[H]OC(=O)C1=C([H])C2=C(C([H])=C1[H])C([H])([H])[C@]1([H])N(C([H])([H])C3([H])C([H])([H])C3([H])[H])C([H])([H])C([H])([H])[C@@]2(C([H])([H])[H])[C@@]1([H])C([H])([H])[H]
[H]OC(=O)[C@@]([H])(N([H])C(=O)C1=C([H])C([H])=C([H])C([H])=C1Br)C([H])([H])C1=C([H])C([H])=C(O[H])C([H])=C1[H]
[H]N(C(=O)N([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C1=C(F)C([H])=C(F)C([H])=C1[H]
[H]N(C(=O)C1=C([H])C([H])=C([H])C([H])=N1)C1=C([H])C(Cl)=C(C([H])=C1[H])N1C(=O)[C@@]2([H])[C@@]3([H])C([H])=C([H])[C@]([H])(C3([H])[H])[C@@]2([H])C1=O
[H]N(C1=NC([H])=NC2=C1C([H])=C(C([H])=C2[H])C1=C([H])C([H])=C2OC([H])([H])OC2=C1[H])C([H])([H])C1=C(C([H])=C([H])S1)C([H])([H])[H]
[H]C1=C([H])C([H])=C2C(=C1[H])N(C([H])([H])[C@@]2([H])C(=O)N(C([H])([H])[H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H])S(=O)(=O)C1=C([H])C([H])=C(OC([H])([H])[H])C2=C([H])C([H])=C([H])C([H])=C12
[H]N(C(=O)C([H])([H])[H])C1=C(OC([H])([H])C([H])([H])C2=C([H])C([H])=C(Cl)C([H])=C2Cl)C([H])=C(C([H])=C1[H])C(=O)N([H])C([H])([H])C1([H])C([H])([H])C([H])([H])N(C2=C([H])C([H])=NC([H])=C2[H])C([H])([H])C1([H])[H]
[H]C1=NC([H])=C(C([H])=C1[H])C1=NC(=NC(=C1[H])C([H])([H])[H])N(C1=C(OC([H])([H])[H])C([H])=C(OC([H])([H])[H])C([H])=C1Br)C([H])([H])C([H])([H])[H]
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[H]N(C(=O)C([H])([H])[H])C1=C([H])C(=C([H])C([H])=N1)C1=C(N=C(SC([H])([H])[H])N1C1([H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]N([H])C1=NC(C2=C([H])N(C3=C([H])C([H])=C([H])C([H])=C23)C([H])([H])[H])=C(I)C([H])=N1
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[H]N1C([H])([H])C(=C([H])C([H])([H])C1([H])[H])C1=NN(N=N1)C([H])([H])C([H])([H])[H]
[H]N(C(=O)C1=C2N([H])[C@@]([H])(C3=C([H])C([H])=C([H])C([H])=C3[H])C([H])([H])C(N2N=C1C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C(C1=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C([H])=C1[H])(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H]
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[H]O[C@]([H])(C([H])([H])N([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C1=C([H])C2=C([H])C([H])=C([H])C([H])=C2C([H])=C1[H])[C@]1([H])N(C([H])([H])C2=C([H])C(Br)=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C1([H])[H]
[H]N1C([H])=C([H])C2=C(N=C([H])N=C12)N(C([H])([H])[H])[C@@]1([H])C([H])([H])[C@@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])[C@]1([H])C([H])([H])[H]
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[H]N([H])C([H])([H])C([H])([H])OC1=C(C([H])=C(C([H])=C1C([H])([H])[H])C(=O)N([H])C1=C([H])C(OC([H])(C([H])([H])[H])C([H])([H])[H])=C([H])C([H])=C1[H])C([H])([H])[H]
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[H]N(C([H])([H])C([H])([H])OC1=NC([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C2=C(C(OC([H])([H])[H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C1([H])[H]
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[H]C1=C([H])C([H])=C(O1)C([H])([H])OC(=O)C1=C([H])N=C(N=C1C(F)(F)F)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
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[H]C1=C([H])C(=C([H])C(C#CC2=C([H])N(C(=O)C([H])=C2[H])C([H])(F)F)=C1[H])S(=O)(=O)C([H])([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C2C(=C1[H])C([H])([H])C([H])([H])[C@]2([H])N(C(=O)N([H])C1=C([H])C(Cl)=C([H])C(Cl)=C1[H])[C@@]1([H])C([H])([H])C([H])([H])[C@]([H])(C([H])([H])C1([H])[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C1=NN([H])N=N1
[H]OC([H])([H])[C@]([H])(N([H])[H])C(=O)N([H])[C@@]([H])(C(=O)N1C([H])([H])C([H])([H])C2(C3=C(C([H])=C([H])C([H])=C3[H])N(C2([H])[H])S(=O)(=O)C([H])([H])[H])C([H])([H])C1([H])[H])C([H])([H])OC([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C1=NC([H])=C([H])C(=C1[H])N1C([H])([H])C([H])([H])C([H])(C(=O)N(C([H])([H])C([H])([H])C([H])([H])S(=O)(=O)C2=C([H])C3=C([H])C([H])=C(Cl)C([H])=C3C([H])=C2[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N1N=C(C2=C1C(=O)N(C1=C([H])C([H])=C([H])C([H])=C1[H])[C@]2([H])C1=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C([H])=C1[H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]O[C@@]([H])(C([H])([H])SC1=NN([H])C([H])=N1)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(OC(=O)N1C([H])([H])C([H])([H])C([H])(N([H])[H])C([H])([H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])SC([H])([H])[H])C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]O[C@@]([H])(C([H])([H])S(=O)(=O)C([H])(C([H])([H])[H])C([H])([H])[H])[C@@]([H])(N([H])C(=O)[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=O)C([H])([H])[H])C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]C1=C([H])C(=C([H])C([H])=C1F)N1C([H])([H])C([H])([H])N(C2=NC3=C(C([H])=C2[H])C(=C([H])C(=N3)C(F)(F)F)C(F)(F)F)C([H])([H])C1([H])[H]
[H]O[C@@]([H])(C1=C([H])C([H])=C([H])C([H])=C1N([H])C(=O)N([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])N1C([H])([H])C([H])([H])C([H])(C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
CN1CCN(CC1)C1=CC=C(N\C=C2/C(=O)NC(=O)C3=CC=C(C=C23)N(O)=O)C=C1
[H]N([H])C([H])([H])C1([H])C2=C([H])C([H])=C([H])C([H])=C2C([H])=C([H])C2=C1C([H])=C([H])C([H])=C2[H]
[H]N(C([H])([H])[H])C([H])([H])C1=C(OC2=C(C([H])=C([H])C([H])=C2[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])=C(N=C1[H])C([H])([H])[H]
[H]N(C(=O)C1=C([H])C(=NN1C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])C(=O)N([H])C([H])([H])C1=C([H])C([H])=C([H])N=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC(C1=C([H])C([H])=C([H])C([H])=C1[H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C(=O)N1C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])[C@]([H])(C#N)C1=C(N=C([H])C([H])=C1[H])C([H])([H])[H]
[H]N([H])C1=C([H])C(=C([H])C([H])=C1[H])N1C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])N2C(=O)C([H])([H])C([H])([H])C3=C2C([H])=C([H])C([H])=C3Cl)C([H])([H])C1([H])[H]
[H]N([H])C1=NC([H])=C(C2=C1C(=C([H])S2)C1=C([H])C([H])=C(N([H])C(=O)N([H])C2=C([H])C([H])=C([H])C(=C2[H])C([H])([H])[H])C([H])=C1[H])C1=C([H])OC([H])=C1[H]