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[H]OC(C1=C([H])C([H])=C(C([H])=C1[H])C1=C(ON=C1N([H])C(=O)N([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H])(C(F)(F)F)C(F)(F)F
[H]OC1=C([H])C([H])=C(C2=C1N([H])C(=O)S2)[C@@]([H])(O[H])C([H])([H])N([H])C([H])([H])C([H])([H])C([H])([H])C1=C([H])C(=C([H])C([H])=C1[H])C([H])([H])N([H])C([H])([H])C([H])([H])C1=C(Cl)C([H])=C([H])C([H])=C1Cl
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[H]N(C(=O)N1C([H])([H])C([H])([H])N(C2=NC(=NS2)C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C(Cl)N=N1
[H]C1=C([H])C2=C([H])C([H])=C(Br)C([H])=C2N1C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C1([H])[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(C1=NC([H])=C([H])C(=C1[H])C1=NN([H])C(=O)N1C1=C([H])C2=C([H])C([H])=C([H])C([H])=C2C([H])=C1[H])C1([H])C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]N(C(=O)C1=C([H])C(=O)C2=C([H])C([H])=C(F)C([H])=C2O1)C1([H])C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C(F)C([H])=C2[H])C([H])([H])C1([H])[H]
[H]OC1=C([H])C([H])=C(OC([H])([H])[C@@]([H])(O[H])C([H])([H])N([H])C([H])([H])C([H])([H])C2=C([H])C([H])=C(N([H])C3([H])C([H])([H])C([H])([H])N(C(=O)N([H])C([H])([H])C4=C([H])C([H])=C(F)C([H])=C4[H])C([H])([H])C3([H])[H])C([H])=C2[H])C([H])=C1[H]
[H]N(C(=O)N([H])[C@@]1([H])N=C(C2=C([H])C([H])=C([H])C([H])=C2[H])C2=C([H])C([H])=C([H])C([H])=C2N(C1=O)C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=N1
[H]C1=C(N(N=C1OC([H])([H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C1=C([H])C([H])=C(Cl)C(Cl)=C1[H])C([H])([H])[H]
[H]OC([H])([H])C([H])([H])ON([H])C(=O)C1=C2N(C(=O)C(F)=C1N([H])C1=C([H])C([H])=C(I)C([H])=C1F)C([H])([H])C([H])([H])C([H])([H])C2([H])[H]
[H]N(C(=O)C1=C([H])C([H])=NC([H])=C1[H])[C@]([H])(C(=O)N1C([H])([H])C([H])([H])C([H])([H])[C@]1([H])C(=O)N([H])[C@@]([H])(C(=O)C(F)(F)F)C([H])(C([H])([H])[H])C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]\C(=C(\[H])C1=C([H])C([H])=C(SC2=C(\C([H])=C(/[H])C(=O)N3C([H])([H])C([H])([H])OC([H])([H])C3([H])[H])C([H])=C([H])C([H])=C2[H])C(Cl)=C1[H])C(=O)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]N([H])C(=O)C1=C(N([H])[H])C2=C(S1)N=C(C([H])=C2C([H])([H])C([H])([H])C([H])([H])[H])N1C([H])([H])C(=O)N([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(C(=O)C1=NN(C2=C([H])C([H])=C([H])C([H])=C12)C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]C([H])=C([H])C([H])([H])O[C@]1([H])C2=C(S[C@]1([H])C([H])([H])N1C([H])=NC([H])=C1[H])C([H])=C(Cl)C([H])=C2[H]
[H]N([H])S(=O)(=O)C1=C([H])C([H])=C(O[C@]([H])(C(=O)OC([H])([H])C([H])([H])[H])C([H])([H])[H])C([H])=C1[H]
[H]N(C(=O)N1C([H])([H])C([H])([H])C([H])(C2=NC(=NO2)C2=C([H])C([H])=C([H])N=C2[H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C([H])C([H])=C1OC([H])([H])[H]
[H]C1=C([H])C2=C(C([H])=C1Cl)C([H])([H])C([H])([H])C1=C(C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])C([H])([H])N2C(=O)C([H])([H])[H]
[H]OC1=C2N([H])C(=O)C([H])=C([H])C2=C(C([H])=C1[H])[C@@]([H])(O[H])C([H])([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C(C(=C1[H])C([H])([H])[H])C([H])([H])C(=O)C1=C([H])C([H])=C(C(=C1[H])N(C(=O)C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])(OC(=O)N([H])C2=C(C([H])=C([H])C([H])=C2[H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H])C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)C([H])([H])[C@@]1([H])N(C([H])([H])C([H])([H])C([H])([H])C1([H])[H])S(=O)(=O)C1=C2N=C([H])C([H])=C([H])C2=C([H])C([H])=C1[H])[C@@]1([H])C2=C(C([H])=C(C([H])=C2[H])C([H])([H])N([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(C([H])([H])C1=C([H])C([H])=C(F)C([H])=C1[H])S(=O)(=O)C1=C([H])C([H])=C2N(C(SC([H])([H])C([H])([H])C3=C([H])C([H])=C([H])C([H])=N3)=NC2=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC1=C([H])C([H])=C(C([H])=C1[H])C1=NC2=C([H])C(O[H])=C([H])C(C3=C([H])C([H])=C([H])O3)=C2O1
[H]C1=C2N(C3=C(C2=C([H])C(Br)=C1[H])C([H])([H])[C@@]([H])(N(C([H])([H])[H])C([H])([H])[H])C([H])([H])C3([H])[H])S(=O)(=O)C1=C([H])C([H])=C(C([H])=C1[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]OC1=C([H])C([H])=C(C2=NC3=C(O[H])C([H])=C([H])C([H])=C3N=C12)C([H])([H])C(\[H])=C(/C([H])([H])[H])C([H])([H])C([H])([H])C([H])=C(C([H])([H])[H])C([H])([H])[H]
[H]N1C2=C([H])C([H])=C(C([H])=C2[C@@]2([H])OC([H])([H])C([H])([H])C([H])([H])[C@@]2([H])[C@]1([H])C1=C([H])C([H])=C([H])C(Cl)=C1[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])C(=C([H])C([H])=C1Cl)C([H])([H])C([H])([H])C1=NN=C(N1C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])N1C(=O)C([H])([H])OC2=C(Cl)C([H])=C(Cl)C([H])=C12
[H]N([H])C(=O)C1=C([H])N=C(OC2=C([H])C3=C(C([H])=C2[H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C3([H])[H])C([H])=C1[H]
[H]N(C(=O)C1=C([H])C([H])=C([H])C2=C([H])C(OC3=C4C([H])=C(C(=O)C([H])([H])[H])C(OC([H])([H])[H])=C([H])C4=NC([H])=C3[H])=C([H])C([H])=C12)C1=C([H])C([H])=C(Cl)C([H])=C1[H]
OCC1=NC2=C(C=C3C(CCC3=C2)N(CC#C)C2=CC=C(C=C2)C(=O)N[C@@H](CCC(=O)N[C@H](CCC(O)=O)C(O)=O)C(O)=O)C(=O)N1
[H]N(C(=O)[C@]1([H])N(C(=O)C2=C([H])C([H])=C([H])C([H])=C12)C([H])([H])C([H])([H])C1=NC([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C(Br)=C1[H]
[H]OC(=O)C([H])([H])N1C2=C(C([H])=C(O[H])C([H])=C2[H])C2=C1C(=S)N(C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C2([H])[H]
[H]C1=C2C(ON=C2C2([H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])OC3=C([H])C([H])=C(C([H])=C3SC([H])([H])[H])C(=O)C([H])([H])[H])C([H])([H])C2([H])[H])=C([H])C(F)=C1[H]
[H]N(C(=O)C([H])([H])[H])C1=NC(=NC(=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H]
[H]N([H])C1=NON=C1N1N=NC(C(=O)N([H])C([H])([H])C([H])([H])C2=C([H])C([H])=NC([H])=C2[H])=C1C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]OC1=C2\C(=C(/[H])N(C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C(=O)O[C@]([H])(C([H])([H])OC([H])([H])[H])[C@@]2(C2=C(C1=O)[C@@]1([H])C([H])([H])C([H])([H])[C@]([H])(O[H])[C@@]1(C([H])([H])[H])C([H])([H])[C@@]2([H])OC(=O)C([H])([H])[H])C([H])([H])[H]
[H]N(C1=C([H])C2=C(C([H])=C1[H])C([H])=C([H])C1=C(C([H])=C(C([H])=N1)C1=C([H])N(N=C1[H])C1=NC([H])=C([H])C([H])=C1[H])C2=O)S(=O)(=O)N(C([H])([H])[H])C([H])([H])[H]
[H]O[C@]1([H])C([H])([H])N=C2N(C1([H])[H])[C@](O[H])(C1=C([H])C([H])=C([H])C([H])=C21)C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]O[C@]([H])(C1=C([H])C([H])=C([H])N=C1[H])C([H])([H])N([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C(N([H])S(=O)(=O)C2=C([H])C([H])=C(C([H])=C2[H])C2=NC(=NO2)C([H])([H])OC2=C([H])C(F)=C(F)C([H])=C2[H])C([H])=C1[H]
[H]N(C(=O)C(\[H])=C(/[H])C1=C([H])C([H])=C(Cl)C(Cl)=C1[H])C1=C([H])C(=C([H])C([H])=C1[H])C([H])([H])C([H])([H])[H]
[H]C1=C2N(C(=N1)C1=C([H])C([H])=C([H])C(Cl)=C1C([H])([H])C([H])([H])C1=C([H])C(Br)=C([H])C([H])=C1OC([H])([H])[H])C([H])([H])C([H])([H])C2([H])[H]
[H]OC1=C([H])C([H])=C([H])C(=C1[H])N(C1=C([H])C([H])=C(C([H])=C1[H])C(=O)N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H]
[H]OC([H])([H])C([H])([H])SC1=C(C#N)C(=C(C#N)C(=N1)N([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C(F)(F)F
[H]O[C@]([H])(C([H])([H])[C@@]([H])(N([H])[H])C([H])([H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])P(=O)(O[H])O[H]
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[H]N1C2=C([H])C([H])=C1\C(=C1/N([H])\C(\C([H])=C1[H])=C(/C1=N/C(/C([H])=C1[H])=C(\C1=N\C(\C([H])=C1[H])=C2\C1=C(F)C([H])=[N+](C([H])=C1[H])C([H])([H])[H])C1=C(F)C([H])=[N+](C([H])=C1[H])C([H])([H])[H])C1=C(F)C([H])=[N+](C([H])=C1[H])C([H])([H])[H])C1=C(F)C([H])=[N+](C([H])=C1[H])C([H])([H])[H]
[H]C([H])=C([H])C([H])([H])N1C(=O)N(C2=C(N3C([H])=C([H])C([H])=C([H])C3=N2)C1=O)C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C1=C([H])C([H])=C([H])C2=C1N=C(O2)C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1N1N=NN=C1[H])C([H])([H])C(F)(F)C1=C([H])C([H])=C([H])C([H])=N1
[H]OC(=O)[C@@]1([H])O[C@]2(O[C@](C(=O)O[H])([C@]([H])(O[H])[C@@]2([H])O[H])[C@]1(O[H])C(=O)O[H])C([H])([H])C([H])([H])C(=C([H])[H])[C@@]([H])(OC([H])([H])C1([H])C([H])([H])C1([H])[H])[C@]([H])(C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C([H])C(OC3=C([H])C([H])=C([H])C([H])=C3OC([H])([H])[H])=C2[H])C([H])([H])C1([H])[H]
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[H]N(C(=O)C1([H])C([H])([H])C1([H])[H])C([H])([H])[C@@]([H])(N([H])C1=C(C([H])=C([H])C([H])=C1[H])C(=O)C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C(OC([H])([H])C([H])([H])C2=C(OC(=N2)C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])[H])C([H])=C1[H]
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[H]N(C(=O)C(\[H])=C(/[H])C1=C([H])N(C2=C([H])C([H])=C([H])C(OC3=C([H])C([H])=C4C([H])=C([H])C([H])=C([H])C4=C3[H])=C12)C([H])([H])[H])S(=O)(=O)C1=C(F)C(F)=C(F)C(F)=C1F
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[H]OC1=NC(=NC2=C([H])C([H])=C(C([H])=C12)C([H])([H])N(C1=C([H])C(F)=C(C([H])=C1[H])S(=O)(=O)C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C#C[H])C([H])([H])[H]
[H]N1C2=C(C(=C([H])C1(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C1=C(C([H])=C2[H])C2=C([H])C(F)=C([H])C([H])=C2O[C@@]1([H])C1=C([H])C(=C(Cl)C([H])=C1[H])C([H])([H])[H]
[H]C([N+]([H])=O)=C1C([H])=C([H])N(C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]N(C(=O)C([H])([H])[H])C1=C2C(=O)C3=C(N([H])N=C3C2=C([H])C([H])=C1[H])C1=C([H])C([H])=C(SC([H])([H])[H])C([H])=C1[H]
[H]N1C(=NC2=C([H])N=C3C([H])=C(Br)C([H])=C([H])C3=C12)C1=C(Cl)C([H])=C([H])C([H])=C1[H]
[H]C1=C([H])C(=C([H])C([H])=C1OC(F)(F)F)C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]OC1=C([H])C(O[H])=C(C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]N1C(=NC2=C(C([H])=C([H])C([H])=C12)N1C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])OC2=C([H])C([H])=C([H])C3=C2N([H])C(=N3)C(F)(F)F)C([H])([H])C1([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])[H]
[H]N(C(=O)C([H])([H])N(C(=O)C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=N1)[C@]1([H])C([H])([H])OC([H])([H])C([H])([H])C1([H])[H])C1=C([H])C(F)=C([H])C(F)=C1[H]
[H]N(C(=O)N([H])C1=C([H])C([H])=C(OC([H])([H])C([H])([H])N2C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])C2=C([H])C([H])=C([H])C([H])=C12)C1=C([H])C(=NN1C1=C([H])C([H])=C(N([H])C(=O)C([H])([H])[H])C([H])=C1[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]OP(=O)(O[H])C(F)(F)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1=C([H])N([H])C2=C1N=C(N([H])[H])N([H])C2=O
[H]C1=C(OC([H])([H])[H])C([H])=C2OC(=O)C(=C([H])C2=C1[H])C(=O)OC([H])([H])C([H])([H])[H]
[H]N(C([H])([H])C1=C([H])C([H])=C(F)C([H])=C1[H])S(=O)(=O)C1=C([H])C([H])=C2N(C(OC([H])([H])C([H])([H])[H])=NC2=C1[H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]N(C1=C2N=C(N(C2=NC(=N1)C([H])([H])[H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])C1([H])C([H])([H])C(F)(F)C1([H])[H])C([H])(C1([H])C([H])([H])C1([H])[H])C1([H])C([H])([H])C1([H])[H]
[H]N(C(=O)N([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC(=C([H])C(=N1)C([H])([H])S(=O)(=O)C([H])([H])[H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]O[C@]([H])(C([H])([H])OC1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])N([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C(N([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])=C1[H]
[H]N1C(=O)N([H])[C@]2(N(C(=O)N([H])C3=C(Cl)C(OC([H])([H])[H])=C(Cl)C([H])=C23)C([H])([H])[H])C1=O
[H]N(C1=C(Cl)C([H])=C(Cl)C([H])=C1[H])C1=C2C(OC([H])([H])[H])=C([H])C([H])=C([H])C2=NC([H])=C1C#N
[H]N(C(=O)C([H])([H])C1=C(N(N=C1C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H])C([H])([H])C1=NC([H])=C([H])C([H])=C1C([H])([H])[H]
FC(F)(F)C1=CC=C(SCC(C2=CNC=N2)C2=CN=CC=C2)C=C1
[H]C([H])=C([H])C([H])([H])S(=O)(=O)C1=C([H])C([H])=C2C(=C1[H])C([H])([H])N([H])C([H])([H])C2([H])[H]
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[H]N(C1=C(Cl)C(=O)C2=C([H])C([H])=C([H])C([H])=C2C1=O)C([H])([H])C([H])([H])C([H])([H])OC([H])(C([H])([H])[H])C([H])([H])[H]
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[H]N1C(=O)\C(=C(\[H])C2=C(C3=C(N2[H])C([H])([H])C([H])([H])C([H])([H])N(C3=O)C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H])C([H])([H])[H])C2=C([H])C(F)=C([H])C([H])=C12
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[H]C1=C([H])C([H])=C(N2C(=O)C3=C([H])C([H])=C([H])C([H])=C3C(C2=O)(C([H])([H])[H])C([H])([H])[H])C(Cl)=C1[H]
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[H]N(C(=O)C1=C([H])N(C2=C(N([H])C(=O)C([H])=C2[H])C1=O)C([H])([H])C1=C(F)C([H])=C([H])C([H])=C1F)C1=C([H])C([H])=C(C([H])=C1[H])C(=O)N([H])C([H])([H])C1=C([H])C([H])=NC([H])=C1[H]
[H]N([H])C(=O)C([H])([H])C([H])([H])N([H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C(C([H])=C2C([H])=NC(SC([H])([H])[H])=NC2=N1)C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C1=C([H])C(=O)OC2=C1C([H])=C([H])C(OC([H])([H])[H])=C2OC([H])([H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H])C1=C(Cl)C([H])=NC([H])=C1Cl
[H]C1=C([H])C2=C(C([H])=C1[H])S(=O)(=O)N(C2=O)C1=C(F)C(F)=NC(F)=C1F
[H]N(C(=O)C1=C(Cl)C([H])=NC([H])=C1Cl)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[C@]([H])(N([H])C(=O)[C@@]1([H])N(C([H])([H])C([H])([H])C1([H])[H])S(=O)(=O)C1=C([H])C(Cl)=C([H])C(Cl)=C1[H])C(=O)C([H])([H])C(=O)OC([H])([H])C([H])([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C(=O)OC1=C2C([H])([H])C([H])([H])[C@@]3([H])[C@]4([H])C([H])([H])C([H])([H])C(=O)[C@@]4(C([H])([H])[H])C([H])([H])C([H])([H])[C@]3([H])[C@@]2(C([H])([H])[H])C([H])([H])C([H])([H])C1([H])[H]
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CC(=O)OCC1=C(N2C([C@H](C(C)=O)C2=O)[S++]([O-])([O-])C1)C(=O)OC(C)(C)C
[H]C1=C([H])C(=C([H])C(OC([H])([H])[H])=C1[H])C([H])([H])C(\C(=O)C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])=C(\C([O-])=O)C1=C([H])C2=NSN=C2C([H])=C1[H]
[H]N1C(=NC2=C([H])C([H])=C([H])C([H])=C12)C([H])([H])SC1=NN=C(N1C([H])([H])C1=C([H])C([H])=C([H])O1)C([H])([H])OC1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]C1=NC(C#N)=C([H])C(=N1)N1C([H])([H])C([H])([H])C([H])(C([H])([H])C1([H])[H])C1([H])C([H])([H])C([H])([H])N(C(=O)OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]OC(=O)C1=C([H])C([H])=C([H])C([H])=C1N([H])C1=C([H])C([H])=C(C([H])=C1C([H])([H])C([H])([H])C(=O)N([H])[H])C([H])([H])[C@@]1([H])N(C(=O)N([H])C([H])(C([H])([H])[H])C([H])([H])[H])C(=O)C(=O)N(C1=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]N(C([H])([H])C(=O)N1C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C#N)[C@]12C([H])([H])[C@@]3([H])C([H])([H])[C@]([H])(C([H])([H])[C@]([H])(C3([H])[H])C1([H])[H])C2([H])[H]
[H]N(C(=O)N([H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])(C([H])([H])C2=C([H])C([H])=C(F)C([H])=C2[H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C(SC([H])([H])[H])C([H])=C1[H]
[H]OC1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])[H])C([H])([H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C([H])([H])N=C(N([H])[H])N([H])[H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])N=C(N([H])[H])N([H])[H])C([H])([H])C1=C([H])C([H])=C(O[H])C([H])=C1[H])C([H])([H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C([H])([H])N=C(N([H])[H])N([H])[H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])N=C(N([H])[H])N([H])[H])C(=O)N([H])[H]
[H]OC1=C([H])C([H])=C(C([H])=C1[H])[C@@]1([H])C2=C([H])C(O[H])=C(O[H])C(Cl)=C2C([H])([H])C([H])([H])[N+]([H])([H])C1([H])[H]
[H]C1=C(N=C(N1C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)C([H])([H])[H])C1=C([H])C(=C([H])C([H])=N1)C([H])([H])[H])C(F)(F)F
[H]OC1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[C@]([H])(N([H])[H])C(=O)N([H])[C@@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])C([H])([H])C(=O)N([H])[C@]([H])(C(=O)N1C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C(=O)N([H])[C@]([H])(C(=O)OC([H])([H])[C@@]1([H])O[C@]([H])(O[H])[C@]([H])(O[H])[C@@]([H])(O[H])[C@]1([H])OC(=O)C([H])([H])[H])C([H])([H])O[H])C([H])([H])C1=C([H])C([H])=C(O[H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H]
[H]OC(=O)[C@@]([H])(OC1=C(C([H])=C2N(C(=O)OC2=C1C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])(C([H])([H])[H])C([H])([H])[H]
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[H]C#C[C@]1([H])N(C(=O)C([H])([H])N([H])C2([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])[C@]([H])(C#N)C([H])([H])C1([H])[H]
[H]N(C(=O)C1=C([H])SC(=N1)N([H])C1=C([H])C([H])=C([H])C([H])=C1Cl)C1=C([H])C([H])=C(C([H])=C1[H])C(F)(F)F
[H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N(C(=O)O[C@@]1([H])C([H])([H])[N@]2C([H])([H])C([H])([H])[C@]1([H])C([H])([H])C2([H])[H])C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]OC(=O)C([H])([H])[C@@]([H])(N([H])C(=O)N([H])N([H])C(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])C1=NC([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C(Br)C([H])=C1[H]
[H]N(C(=O)C1=C(N([H])C(=O)C2=C([H])C([H])=C(C([H])=C2[H])C2=NC([H])([H])C([H])([H])N2C([H])([H])C([H])([H])[H])C([H])=C([H])C(Cl)=C1[H])C1=C([H])C([H])=C(Cl)C([H])=N1
[H]C1=C([H])C(=O)N2C(=C1[H])[C@@]1([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])C(=O)C([H])([H])[H])C([H])([H])[C@@]([H])(C2([H])[H])C1([H])[H]
[H]O[C@@]([H])(C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])[C@]([H])(O[H])[C@@]([H])(N([H])C(=O)[C@@]([H])(OC([H])([H])C([H])([H])[H])N([H])C(=O)[C@@]([H])(N([H])S(=O)(=O)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]C1=C([H])C(=C([H])C(OC([H])([H])[H])=C1OC([H])([H])[H])C1=NN2C(SC1([H])[H])=NN=C2C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]C1=C([H])C([H])=C(O1)C(=O)OC1=C([H])C2=C(C([H])=C1[H])C(=C([H])C(=O)O2)C([H])([H])[H]
[H]N(C([H])([H])[H])[C@@]1([H])C2=C([H])C([H])=C([H])C([H])=C2[C@]([H])(C2=C([H])C([H])=C(Cl)C(=C2[H])C(F)(F)F)C([H])([H])C1([H])[H]
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[H]OC1=NC([H])=C([H])C2=C1C([H])=C([H])C([H])=C2O[H]
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[H]C1=C([H])C([H])=C(OC([H])([H])C([H])([H])SC(=S)SC([H])([H])C(=O)C2=C([H])C([H])=C(OC([H])([H])[H])C([H])=C2[H])C([H])=C1[H]
CC1CC(O)(C#CC2=CC=CC3=CC=CC=C23)C(C)CN1C
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[H]C1=C(Cl)C([H])=C2C(=O)C3=C(N(N=C3C([H])([H])[H])C([H])([H])[H])N(OC([H])([H])C([H])([H])C([H])([H])[H])C2=C1[H]
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[H]N(C(=O)N1C([H])([H])C([H])([H])N(C2=NC(=NO2)C2=C([H])C([H])=C3C([H])=C([H])C([H])=C([H])C3=N2)C([H])([H])C1([H])[H])C([H])([H])C1(N2C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
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[H]N(C(=O)N(C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C([H])C(C#N)=C1[H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C(F)C(Cl)=C1[H]
[H]N([H])C1=NC([H])=C([H])N2C(=NC(=C12)C1=C([H])C([H])=C(OC2=C([H])C([H])=C([H])C([H])=C2C([H])([H])[H])C(F)=C1[H])C1([H])C([H])([H])C([H])([H])C1([H])[H]
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[H]N(C(=O)OC([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])N=C(N(C1=O)C([H])([H])C(=O)N([H])[C@@]([H])(C(=O)C(F)(F)F)C([H])(C([H])([H])[H])C([H])([H])[H])C1=C([H])C(=C([H])C(=C1[H])C(F)(F)F)C(F)(F)F
[H]N(C(=O)N([H])C1=C([H])C([H])=C([H])C2=C([H])C([H])=C([H])C([H])=C12)C1=C(C([H])=C(S1)C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C(=O)N1C([H])([H])C([H])([H])SC([H])([H])C1([H])[H]
[H]N(C1=C([H])C([H])=C(C([H])=C1[H])C(=O)C([H])([H])SC(=S)SC([H])([H])C([H])([H])[H])S(=O)(=O)C([H])([H])[H]
[H]OC(=O)[C@]1([H])N([H])C(=O)[C@]([H])(N([H])C(=O)C([H])([H])N([H])C(=O)[C@]([H])(N([H])C(=O)[C@]([H])(N([H])[H])C([H])([H])C2=C([H])C([H])=C(O[H])C([H])=C2[H])C(SSC1([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C1=C([H])C(=C([H])C([H])=C1Cl)C([H])([H])SC1=NN=C(N1C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])N1C(=O)C([H])([H])SC2=C([H])C([H])=C(C([H])=C12)C(F)(F)F
[H]C1=C(OC(=O)OC([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C2=C(C([H])=C1OC(=O)OC([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C(=O)C1=C([H])C(=C([H])C(OC(=O)OC([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])=C1C2=O)C([H])([H])[H]
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[H]OC([H])([H])[C@]1(OC(=O)\C(=C(\[H])C2=C([H])C(Br)=C(F)C([H])=C2[H])C1([H])[H])C([H])([H])OC(=O)C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])C([H])=C(C(C#N)=C1[H])S(=O)(=O)C1([H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C2=C([H])C([H])=C(F)C([H])=C2F)C([H])([H])C1([H])[H]
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[H]N=C(N([H])[H])C1=C([H])C([H])=C([H])C(=C1[H])C([H])([H])[C@@]([H])(C(=O)OC([H])([H])[H])[C@]([H])(N([H])C(=O)C1=C([H])C([H])=C(C([H])=C1[H])N1C([H])=NC([H])=C1[H])C([H])([H])[H]
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[H]OC(=O)C1=C([H])C(OC2=C([H])C(=C([H])C([H])=C2[H])C2=NC([H])([H])C([H])([H])N2[H])=NC(OC2=C([H])C(=C([H])C([H])=C2O[H])C(=N[H])N([H])[H])=C1[H]
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[H]N([H])C(=O)C1=C2N([H])C3=C(C([H])=C(F)C([H])=C3[H])C2=C(N=C1[H])N([H])C1([H])C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]N(C1=NC(=O)\C(S1)=C(/[H])C1=C([H])C([H])=C([H])N1C([H])([H])[H])C1=C([H])C(=C(C([H])=C1[H])C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C1=NC(OC(=O)C([H])([H])[H])=C(S1)C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(\C(=N/C#N)N([H])[C@@]1([H])C(=O)N(C([H])([H])C(=O)N2C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C1=C([H])C2=C(OC(=C2[H])C([H])([H])[H])C([H])=C1[H]
[H]C1=C([H])C([H])=C(O1)C([H])([H])N1C([H])([H])C([H])([H])[C@]2(O[C@@]([H])(OC([H])([H])[H])C([H])([H])C3=C2C([H])=C(S3)C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N(C(=O)C1=C([H])C(=C([H])C([H])=C1[H])C([H])([H])[H])C1=C([H])C([H])=C([H])C(=N1)C([H])([H])[H]
[H]N(N1C(SC([H])([H])C#N)=NN=C1C([H])([H])C1=C([H])SC(=N1)N([H])C(=O)C([H])([H])Cl)C(=O)C([H])([H])[H]
[H]N=C(N([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N([H])C(=O)C([H])([H])N1C(=O)C(=NC(Cl)=C1C1=C([H])C([H])=C([H])C([H])=C1[H])N([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[3H]C1=CC([3H])=C([3H])C(=C1)C1=NC2=C(N1)C1=N[C@H](CC)CN1C(=O)N2C
[H]OC1=C([H])C([H])=C(\C([H])=C2/OC(=S)N(C2=O)C2=C([H])C([H])=C(OC([H])([H])[H])C([H])=C2[H])C([H])=C1C([H])([H])[H]
[H]O[C@]([H])(C([H])([H])N([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])[C@@]([H])(N([H])C(=O)C1=C([H])C(=C([H])C(N([H])C([H])([H])C([H])([H])[H])=C1[H])N1C(=O)C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC(=O)[C@]([H])(SC1=NC(N([H])C2=C(C(=C([H])C([H])=C2[H])C([H])([H])[H])C([H])([H])[H])=C([H])C(Cl)=N1)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]C1=C(C2=C(O1)C1=C(C(=O)C2=O)C2=C(C([H])=C1[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])[H]
[H]OC([H])([H])C([H])([H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])OC2=C([H])C3=NC([H])=NC(N([H])C4=NN([H])C(=C4[H])C([H])([H])C(=O)N([H])C4=C(F)C(F)=C([H])C([H])=C4[H])=C3C([H])=C2OC([H])([H])[H])C([H])([H])C1([H])[H]
[H]C1=C(C(=O)C2([H])C(C([H])([H])[H])(C([H])([H])[H])C2(C([H])([H])[H])C([H])([H])[H])C2=C(C([H])=C(C([H])=C2[H])S(=O)(=O)C([H])([H])[H])N1C([H])([H])C1([H])C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]O[C@]1([H])[C@]([H])(O[C@@]([H])(C2=C([H])C(=C(Cl)C([H])=C2[H])C([H])([H])C2=NC([H])=C(S2)C2=C([H])C([H])=C([H])O2)[C@]([H])(O[H])[C@@]1([H])O[H])C(=O)OC([H])([H])[H]
[H]OC1=NC2=C([H])C([H])=C([H])C([H])=C2N1C1([H])C([H])([H])C([H])([H])N(C(=O)C([H])([H])C2=C(C([H])=C(OC([H])([H])[H])C(OC([H])([H])[H])=C2[H])[N+]([O-])=O)C([H])([H])C1([H])[H]
[H]C1=C([H])C([H])=C(O1)C1=C(SC(=N1)N(C([H])([H])C1=C([H])C([H])=C([H])O1)C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C(=O)C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N1C([H])=C2C(=C1\C([H])=C1/C(=O)N([H])C3=C([H])C(=C([H])C([H])=C13)C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])N([H])C2=O
[H]C1=C([H])C(=C([H])C([H])=C1Cl)C([H])([H])C(=O)N(C([H])([H])[H])[C@]([H])(C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]O[C@]1([H])C2=C(N3C([H])([H])C([H])([H])C([H])([H])C3([H])[H])C(C(=O)C3=C([H])C([H])=C(C([H])=C3[H])C(F)(F)F)=C(N=C2C([H])([H])C(C([H])([H])[H])(C([H])([H])[H])C1([H])[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(C(=O)C1=NN(C(N2C(=C([H])C([H])=C2C([H])([H])[H])C([H])([H])[H])=C1C([H])([H])C([H])([H])[H])C1=C([H])C([H])=C(Cl)C([H])=C1Cl)C([H])([H])C1=C([H])C(Cl)=C(Cl)C([H])=C1[H]
[H]N(C(=O)OC([H])([H])C([H])([H])C([H])([H])C1=C([H])N([H])C([H])=N1)C1=C([H])C([H])=C(OC(F)(F)F)C([H])=C1[H]
[H]OC(=O)[C@]([H])(OC1=C([H])C([H])=C(SC([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C1=C([H])C([H])=C2C(N=C3N(N(C(=O)C3=C2C([H])([H])[H])C2=C([H])C([H])=C(F)C([H])=C2[H])C([H])([H])C(=O)N(C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[H])=C1[H]
CCCS(=O)(=O)N1CCN(CC1)C1(CNC(=O)C2=C(F)C=CC=C2F)CCC2(CC2)CC1
[H]N([H])C(=NC1=NC(=C([H])S1)C([H])([H])SC([H])([H])C([H])([H])N([H])C(=O)C([H])([H])C([H])([H])N([H])C(=O)C([H])([H])N1C2=C([H])C([H])=C([H])C([H])=C2C(=N[C@@]([H])(N([H])C(=O)N([H])C2=C([H])C(=C([H])C([H])=C2[H])C([H])([H])[H])C1=O)C1=C([H])C([H])=C([H])C([H])=C1[H])N([H])[H]
[H]N([H])C1=C([H])C([H])=C([H])C([H])=C1N([H])C(=O)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1N=NC2=C([H])C([H])=C([H])C([H])=C2C1=O
[H]OC([H])([H])C([H])([H])OC1=C([H])C(N2N=C([H])C([H])=N2)=C(C([H])=C1[H])C(=O)N1C([H])([H])[C@]([H])(OC2=NC([H])=C([H])C(C#N)=C2[H])C([H])([H])C([H])([H])[C@@]1([H])C([H])([H])[H]
[H]C1=C([H])C(=C([H])C([H])=C1Cl)C1=C([H])C([H])([H])N(C([H])([H])C([H])([H])C(=O)C2=C([H])C(Cl)=C(Cl)C([H])=C2[H])C([H])([H])C1([H])[H]
[H]C1=NC2=C(C([H])=C1[H])C([H])=C([H])C1=C(C([H])=C([H])C(Cl)=C1[H])[C@]2([H])N1C([H])([H])C([H])([H])N(C(=O)C([H])([H])[C@]2([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]N(C(=O)C(=O)[C@@]([H])(N([H])C(=O)[C@]1([H])N(C([H])([H])C([H])([H])[H])S(=O)(=O)C2=C([H])C3=C(OC([H])([H])C([H])([H])O3)C([H])=C2C1([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])OC([H])([H])[H]
[H]N1C([H])=C(C2=C1C([H])=C([H])C([H])=C2[H])C1=C([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2=C([H])C([H])=NC([H])=C2[H])C([H])([H])C1([H])[H]
[H]OC([H])([H])C(=O)C([H])([H])[C@@]1([H])C([H])([H])C([H])([H])[C@]([H])(C([H])([H])C([H])([H])N2C([H])([H])C([H])([H])N(C3=NC([H])=C([H])C4=C3C([H])=C([H])S4)C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]OC(=O)C1=C(N([H])C2=NC(=NC([H])=C2[H])N([H])C2([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])=C([H])C([H])=C1[H]
[H]N=C(N([H])[H])N([H])C([H])([H])C([H])([H])C([H])([H])[C@@]([H])(N([H])C(=O)C([H])([H])N1C(=O)C([H])([H])N(C([H])([H])C1([H])[H])S(=O)(=O)C1=C([H])C([H])=C(Br)C([H])=C1[H])C(=O)C1=NC([H])=C([H])S1
[H]N1C(=NC([H])([H])C1([H])[H])C([H])([H])OC1=C(C([H])=C([H])C([H])=C1[H])C1=C([H])C(=C([H])C([H])=N1)C([H])([H])[H]
[H]N(C1=NC([H])=NC2=C1C([H])=C([H])C(OC([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])C1([H])[H])=C2[H])C1=C([H])C([H])=C(C(N([H])C2=NC([H])=C(C([H])=N2)C2=C([H])C([H])=C([H])N=C2[H])=C1[H])C([H])([H])[H]
COC1=CC(NC2=C3C=NN(C)C3=NC(=N2)C2=C3C=NNC3=CC=C2)=CC=C1
[H]C([H])=C([H])C([H])([H])N(C(=O)OC([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])[N+]([O-])=O)C1([H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])[C@](C2=C([H])C([H])=C([H])C([H])=C2[H])(C([H])([H])[H])C([H])([H])N2C([H])=NC3=C2C([H])=C([H])C([H])=C3[H])C([H])([H])C1([H])[H]
[H]O[C@@]([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])[C@]([H])(N(C(=O)N([H])C1=C([H])C([H])=C(OC2=C([H])C([H])=C(Cl)C([H])=C2[H])C([H])=C1[H])C([H])([H])[H])C([H])([H])[H]
[H]N1C(=O)C2=NN(C(=O)N2C2=C1C(=C([H])C([H])=C2[H])[N+]([O-])=O)C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]C1=NC(OC2([H])C([H])([H])C([H])([H])N(C3=C([H])C([H])=C([H])C(Cl)=N3)C([H])([H])C2([H])[H])=C(C([H])=C1[H])C1([H])C([H])([H])C([H])([H])N(C(=O)C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N([H])C(=O)C1=C([H])C(=NN1C([H])([H])C([H])([H])[H])C([H])([H])N1C(=O)C2=C([H])C([H])=C(Cl)C([H])=C2C(C2=C([H])C([H])=C([H])C([H])=C2[H])=C1C(=O)C([H])([H])C([H])([H])[H]
[H]N1C2=C([H])C([H])=C(OC([H])([H])[H])C([H])=C2C(=C1C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C(=O)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]OC1=C([H])C([H])=C(\C([H])=C2/C(=O)N([H])N(C2=O)C2=C([H])C([H])=C(C#N)C([H])=C2[H])C([H])=C1OC([H])([H])[H]
[H]N1C2=C([H])C([H])=C(F)C([H])=C2C2=C1C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C1=C([H])C([H])=NC([H])=C1[H])C2([H])[H]
[H]N=C(N([H])[H])N([H])C([H])([H])C([H])([H])C([H])([H])[C@]([H])(N([H])C(=O)C([H])([H])N1C(=O)[C@@]([H])(N(C([H])([H])C1([H])[H])S(=O)(=O)C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C(=O)OC([H])([H])[H])C(=O)C1=NC([H])=C([H])S1
[H]OC(=O)C([H])([H])C([H])([H])N([H])C([H])([H])C1=C([H])C(F)=C(C([H])=C1[H])C1=NC2=C(S1)N=C(C([H])=C2[H])C1(C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
OC(C1=CN=C(S1)N1CCN(CC1)C1=CC=CC(=C1)[N+]([O-])=O)(C(F)(F)F)C(F)(F)F
[H]OC(=O)C1=C(C([H])=C([H])C(=C1[H])C1([H])C([H])([H])C1([H])[H])C([H])([H])C1=C([H])N=C(N=C1[H])C1=C([H])C([H])=C([H])C([H])=C1C1([H])C([H])([H])C1([H])[H]
[H]C1=C([H])N(C([H])=N1)C1=C([H])C([H])=C(OC([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H])C([H])=C1[H]
[H]OC(=O)C([H])([H])C1=C(N(C2=C([H])C([H])=C(OC([H])([H])[H])C([H])=C12)C1=C2C([H])=C([H])C(Cl)=C([H])C2=NC([H])=C1[H])C([H])([H])[H]
[H]N([H])C1=NC(=NC2=NC(=NN12)C1=C([H])C([H])=C([H])O1)N1C([H])([H])C([H])([H])N(C(=O)C([H])([H])C([H])([H])C(=O)OC([H])([H])[H])C([H])([H])C1([H])[H]
[H]OC1(C2=C([H])C([H])=C(Cl)C([H])=C2[H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])N([H])S(=O)(=O)C2=C(Cl)C([H])=C([H])C(Cl)=C2[H])C([H])([H])C1([H])[H]
[H]OC(=O)C([H])([H])SC1=C2SC(=C([H])C2=NC([H])=N1)C1=C([H])C([H])=C(N([H])C(=O)C([H])([H])[H])C([H])=C1[H]
[H]OC(=O)[C@]([H])(N([H])C(=O)[C@]([H])(C([H])([H])S[H])[C@@]1([H])C2=C(C([H])=C(C([H])=C2[H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H])C([H])([H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H]
[H]OC(=O)C1=C([H])C([H])=C([H])C(=C1[H])C1=C(C([H])=C([H])S1)C1=C([H])C(Cl)=C([H])C([H])=C1OC([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N([H])C1=C([H])C2=NC([H])=NC(N([H])C3=C([H])C([H])=C([H])C([H])=C3[H])=C2C([H])=N1
[H]OC1=C([H])C([H])=C(OC2=C([H])C(=C([H])C([H])=C2[H])C([H])([H])C([H])([H])N2C([H])([H])C([H])([H])[C@]3(N(C(=O)[C@@]([H])(N([H])C3=O)C([H])([H])C3([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C3([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C2([H])[H])C([H])=C1[H]
[H]OC1=C(F)C2=C(C(F)=C1O[H])[C@]([H])(N([H])C([H])([H])C2([H])[H])C([H])([H])C1=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C(OC([H])([H])[H])=C1[H]
[H]N(C(=O)C([H])([H])N1C(=O)C2=C([H])C([H])=C([H])N2C2=C(C([H])=C([H])N=C12)C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C([H])C([H])=C(C([H])=C2[H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]OC(=O)C1=C([H])SC(=C1[H])S(=O)(=O)N1C([H])([H])C([H])([H])C([H])(C(=O)N([H])C2([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
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[H]O[C@@]12C([H])([H])C([H])([H])C(=O)[C@]3([H])OC4=C(N([H])[H])C([H])=C([H])C5=C4[C@]13C([H])([H])C([H])([H])N(C([H])([H])C1([H])C([H])([H])C1([H])[H])[C@]2([H])C5([H])[H]
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[H][C@@]12C[C@H](O)CC[C@@]1([H])C(C)(C)OC1=C2C(O)=CC(=C1)C1(CCCCCC)CCC1
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[H]N(C(=O)C1=NC([H])=C([H])C([H])=C1[H])C1=C([H])C(OC(F)(F)F)=C([H])C([H])=C1[H]
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[H]N(C(=O)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N([H])C([H])([H])C([H])([H])[H])C1=NN(C(=C1[H])C([H])([H])[H])C([H])([H])C1=C([H])C(Cl)=C([H])C([H])=C1OC([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N([H])C1=NC(=C([H])C(=N1)C1=NC(=C([H])S1)C([H])([H])[H])C(=O)N([H])C([H])([H])C1=NC([H])=C([H])C([H])=C1[H]
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[H]N1C(=NC([H])([H])C1([H])[H])C([H])([H])C1=C(C([H])=C(Br)C([H])=C1C([H])([H])[H])C([H])([H])[H]
[H]N([H])C(=O)C1=C(N=C(N=C1[H])N([H])C([H])([H])C([H])([H])N([H])[H])N([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C1=C(SC2=C1N=C([H])N(C2=O)[C@]1([H])C([H])([H])N(C(=O)N(C([H])([H])[H])[C@]2([H])C([H])([H])N(C([H])([H])C2([H])[H])C2([H])C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C(OC([H])([H])C([H])([H])[H])C([H])=C1Cl
[H]OC([H])([H])[C@]([H])(N1C([H])([H])C([H])([H])C([H])(C2=NOC3=C([H])C(F)=C([H])C([H])=C23)C([H])([H])C1([H])[H])C([H])([H])N1C([H])([H])C2=C([H])C([H])=C(Cl)C([H])=C2C1([H])[H]
[H]OC1=C([H])C([H])=C(N([H])C(=O)C2=NC([H])=NC(N([H])C3([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C3([H])[H])=C2[H])C([H])=C1[H]
[H]N([H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C2=C3N(N=C([H])N=C3N([H])C3=C([H])C([H])=C([H])C(F)=C3[H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N(C(=O)C1=NC2=C([H])C([H])=C([H])C([H])=C2C(C2=C([H])C([H])=C([H])C([H])=C2[H])=C1C([H])([H])[H])[C@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])[H]
[H]C1=C(F)C(F)=C([H])C(=C1[H])S(=O)(=O)N1[C@]([H])(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[C@]1([H])C1(OC(=O)N2C([H])([H])C([H])([H])C([H])(N3C([H])([H])C([H])([H])C([H])([H])C([H])([H])C3([H])[H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
OC(CNC1CCN(CC1)C1=NC=NC2=C1SC=C2)COC1=CC=CC=C1
[H]C1=C([H])C([H])=C(C([H])=N1)C1=NC(C2=C([H])C([H])=C([H])C([H])=C2Cl)=C(C([H])=C1C#N)C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]N(C(=O)C1=C(C([H])=C([H])S1)S(=O)(=O)N([H])C1=C(Cl)C(=NO1)C([H])([H])[H])C1=C(C([H])=C(C([H])=C1Cl)C([H])([H])[H])C([H])([H])[H]
[H]N([H])C(=O)C1=NN(C2=C1C([H])=C([H])C1=C2C([H])=NN1[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H]
[H]N([H])C1=NC([H])=C([H])N2C(=NC(=C12)C1=C(C([H])=C(OC2=C([H])C([H])=C([H])C([H])=C2[H])C([H])=C1[H])C(F)(F)F)C1([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(N1[C@@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C([H])([H])[H])C(=O)C1=NN(C(=C1C([H])([H])N1N=C([H])N=C1[H])C1=C([H])C([H])=C(Cl)C([H])=C1[H])C1=C([H])C([H])=C(Cl)C([H])=C1Cl
[H]OC(=O)C1=C(N([H])C(=O)C([H])([H])C([H])([H])C2=C([H])C3=C(C([H])=C2[H])C([H])=C(O[H])C([H])=C3[H])C([H])([H])C([H])([H])[C@]([H])(C([H])([H])C([H])([H])C([H])([H])[H])C1([H])[H]
[H]ON([H])C(=O)C([H])([H])OC1=C([H])C([H])=C2C(=C1[H])C([H])([H])N([H])[C@]([H])(C(=O)N([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C2([H])[H]
[H]C1=C([H])C(=C(C([H])=C1[H])S(=O)(=O)N(C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H])C([H])([H])C(=O)N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C(=C([H])C([H])=C1[H])C1=NC(=NC(=C1[H])C([H])([H])[H])N(C1=C(Br)C([H])=C(C([H])=C1[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])[H]
[H]OC(=O)C([H])([H])[C@]1([H])N(C(=O)C2=C([H])C([H])=C(C([H])=C2[H])C2=NC([H])([H])C([H])([H])N2C([H])([H])[H])C([H])([H])C([H])([H])N(C1([H])[H])S(=O)(=O)C1=C([H])C2=C(N1[H])C([H])=C([H])C(Cl)=C2[H]
[H]C1=C([H])C(=C([H])C(=C1[H])C([H])([H])Br)C(=O)C(F)(F)F
[H]O[C@]([H])(C([H])([H])OC1=C([H])C([H])=C([H])C([H])=C1C(=O)C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])N([H])C1=C([H])C([H])=C(C([H])=C1[H])C(F)(F)F
[H]OC1=C([H])C(\C([H])=C(/C#N)C(=O)N([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=O)C(\C#N)=C(/[H])C2=C([H])C(O[H])=C(O[H])C(O[H])=C2[H])=C([H])C(O[H])=C1O[H]
[H]N(C(=O)C1=C([H])C([H])=C(S1)C1=C([H])C([H])=C([H])C([H])=N1)C1=C([H])C(OC([H])([H])[H])=C(C([H])=C1[H])C1=C([H])N=C([H])O1
[H]OC([H])([H])C(=O)N([H])C1=C([H])C2=C(N=C([H])N(C2=O)C([H])([H])C2=C([H])C([H])=C(Cl)C([H])=C2[H])N=C1[H]
[H]O[C@@]1([H])C([H])([H])C2=C(C([H])=C([H])C([H])=C2N([H])C2=NC(=C(O2)C2=C([H])C([H])=C(C([H])=C2[H])C(F)(F)F)C2=C([H])C([H])=C(C#N)C([H])=C2[H])C([H])([H])C1([H])[H]
[H]C1=C([H])C(=C([H])C([H])=C1OC([H])([H])[H])C1=NC(=C(O1)C([H])([H])[H])C([H])([H])C([H])([H])OC1=C([H])C([H])=C2C(OC(=O)[C@@]([H])(C(=O)OC([H])([H])[H])C2([H])[H])=C1[H]
[H]N(C(=O)C1=C([H])C(OC2=C([H])C(=C([H])C([H])=C2C#N)C([H])([H])N2C([H])=NC([H])=C2[H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C#CC([H])([H])N1C(=O)C2=C(SC(=C2C([H])([H])[H])C([H])([H])[H])N=C1C([H])([H])[H]
[H]OC1=C([H])C([H])=C(N([H])C2=C(Cl)C(=O)C3=C([H])C([H])=C([H])C([H])=C3C2=O)C([H])=C1[H]
[H]N(C(=O)[C@]([H])(OC1=C2C(=NC([H])=NC2=C([H])C([H])=C1[H])N([H])C1=C([H])C2=C(C([H])=C1[H])N(N=C2[H])C([H])([H])C1=C([H])C([H])=C([H])C(F)=C1[H])C([H])([H])[H])C([H])([H])[H]
[H]O[C@@]1([H])OC(=O)C([H])([H])[C@]1([H])N([H])C(=O)[C@@]([H])(N([H])C(=O)C([H])([H])OC1=C(C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]C1=NC2=C(C([H])=C1[H])C([H])=C([H])C([H])=C2S(=O)(=O)N1C([H])([H])C([H])([H])C([H])(N2C(=O)OC([H])([H])C3=C([H])C([H])=C([H])C([H])=C23)C([H])([H])C1([H])[H]
[H]C1=C([H])C(=C([H])C([H])=C1Cl)N1C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C(OC([H])([H])C([H])([H])F)C(OC([H])([H])[H])=C2[H])C([H])([H])C1([H])[H]
[H]OC(=O)C1=C([H])C([H])=C(C([H])=C1[H])C1=NOC(=C1[H])C1=C([H])C2=C(C([H])=C1[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C([H])([H])C2(C([H])([H])[H])C([H])([H])[H]
[H]O[C@]([H])(C([H])([H])N(C(=O)C1=C([H])C2=C(N=C(O2)N([H])C([H])([H])C([H])([H])C([H])([H])N2C([H])=NC([H])=C2[H])C([H])=C1[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])[C@@]([H])(N([H])C(=O)OC([H])([H])C1=C([H])N=C([H])S1)C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)C([H])([H])OC([H])([H])[H])C1=C([H])C([H])=C(OC2=C([H])C(OC([H])([H])[H])=C([H])C([H])=C2[H])C([H])=C1[H]
[H]N([H])C1=NC([H])=C([H])N2C(=NC(=C12)C1=C([H])C([H])([H])N(C([H])([H])C1([H])[H])S(=O)(=O)C1=C([H])C([H])=C([H])C([H])=C1[H])C1([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(C1=C([H])C([H])=C2C([H])=C(N([H])C2=C1[H])C(=O)N1C([H])([H])C([H])([H])C([H])(C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H])S(=O)(=O)C([H])([H])[H]
[H]N(C(=O)N1C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C([H])C(OC3=C([H])C([H])=C(Cl)C([H])=C3[H])=C2[H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C([H])N=C1[H]
[H]OC1=C([H])C([H])=C2N(C([H])=C(C2=C1[H])C1(C([H])([H])N([H])C(=O)C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])[H]
[H]OC([H])([H])C([H])([H])N([H])S(=O)(=O)C1=C([H])C([H])=C(C([H])=C1[H])C1=C2C([H])=C(N([H])C2=NC([H])=C1[H])C([H])([H])[H]
[H]O[C@]1(C2=C([H])C(F)=C(F)C([H])=C2[H])C([H])([H])C([H])([H])N([H])C([H])([H])[C@]1([H])C1=NOC(=C1[H])C1=C([H])C([H])=C([H])C([H])=C1C([H])([H])C([H])([H])N([H])C(=O)C([H])([H])[H]
[H]OC(=O)C(OC1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N(C([H])([H])C(=O)N([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1Cl)C([H])([H])C1=C([H])C([H])=C([H])O1)(C([H])([H])[H])C([H])([H])[H]
[H]OC(=O)[C@@]([H])(N([H])C(=O)C1=C(C([H])=C(C([H])=C1C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])N1C(=O)C([H])([H])[C@]([H])(C([H])([H])N([H])C2=NC([H])=C([H])C(=C2[H])C([H])([H])[H])C1([H])[H]
[H]N=C(N([H])[H])N([H])C([H])([H])C([H])([H])C([H])([H])[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)C([H])([H])C(F)(F)F)C([H])([H])C1=C([H])C([H])=C(Cl)C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C(=O)N([H])[C@]([H])(C(=O)N([H])[H])C([H])([H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H]
[H]N([C@@]([H])(C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])C([H])([H])[H])[C@]1([H])C([H])([H])C([H])([H])[C@@]([H])(C(=O)N2C([H])([H])C([H])([H])C(N3C(=O)N([H])C([H])([H])C([H])([H])C3([H])[H])(C3=C([H])C([H])=C([H])C([H])=C3[H])C([H])([H])C2([H])[H])C(C([H])([H])[H])(C([H])([H])[H])C1([H])[H]
[H]OC1=C([H])C(O[H])=C(C([H])=C1[H])C1=C([H])C2=C([H])C([H])=C(O[H])C([H])=C2C([H])=C1[H]
[H]N1C(=O)C2=C([H])C([H])=C([H])C3=C2[C@@]([H])(N(C(=O)C([H])([H])C2=C([H])C([H])=C(Br)C([H])=C2[H])C([H])([H])C3([H])[H])C1([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1C2=C([H])C([H])=C(C([H])=C2N=C1C([H])([H])C1=C([H])C([H])=C(OC([H])([H])C([H])([H])[H])C([H])=C1[H])C(=O)N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H]
[H]C1=C([H])C(=C([H])C([H])=C1Cl)C1=C(C(=NN1C1=C([H])C([H])=C(Cl)C([H])=C1Cl)C1=NN=C(O1)C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])OC([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]N1C(=O)N([H])C(=O)C(N2C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])O[N+]([O-])=O)C([H])([H])C2([H])[H])(C1=O)C1=C([H])C([H])=C(OC2=C([H])C([H])=C([H])C([H])=C2[H])C([H])=C1[H]
[H]N(C(=O)N([H])C1=C([H])C([H])=C([H])C(Cl)=C1[H])C1=NC(=O)[C@]([H])(N1C([H])([H])C([H])([H])[H])C([H])([H])[H]
C[N](C)(C)C1=CC(=CC=C1)C(=O)C(F)(F)F
[H]C1=C([H])C(OC([H])([H])C2=C([H])C([H])=C(F)C([H])=C2[H])=C([H])C(=O)N1C([H])([H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H]
CN1C=CC2=C1C(OC1=CC=C(NC(=O)NC3=CC(=NC=C3)C(F)(F)F)C(Cl)=C1)=NC=N2
[H]OC(=O)[C@@]([H])(N([H])C1=C(C#N)C(=NC2=C([H])C([H])=C(F)C([H])=C12)C1=C([H])C([H])=C(C([H])=C1[H])C1=C(OC([H])([H])C([H])([H])[H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H]
[H]N(C1=C([H])C([H])=C(C([H])=C1Cl)C([H])([H])[H])[C@@]([H])(C(=O)C([H])([H])C([H])([H])C1=C([H])C([H])=NC([H])=C1[H])C1=C(C([H])=C([H])C([H])=C1[H])C([H])([H])[H]
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[H]N(C(=O)N([H])C1=C([H])C(Br)=C(C([H])=C1[H])C([H])([H])[H])C1=C([H])C([H])=C(N([H])C2=NC([H])=NC3=C([H])C(OC([H])([H])C4([H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C4([H])[H])=C([H])C([H])=C23)C([H])=C1[H]
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[H]N(C(=O)C(=O)C1=C2C([H])=C([H])C([H])=C([H])C2=C(OC([H])([H])C([H])([H])N2C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])C([H])=C1[H])C1=C(OC([H])([H])[H])C(N([H])S(=O)(=O)C([H])([H])[H])=C([H])C(=C1[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
CCCS(=O)(=O)N1CCN(CC1)C1(CNC(=O)C2=CC(Cl)=C(Cl)C=C2)CCCCC1
[H]N(C(=O)C1=C(C([H])=C([H])C(=C1[H])N1C(=O)C([H])=C([H])C1=O)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C1=C([H])C(Cl)=C(C([H])=C1[H])C([H])([H])[H]
[H]N(C(=O)C([H])([H])C([H])([H])[C@]1([H])OC2=C([H])C([H])=C([H])C([H])=C2OC1([H])[H])C([H])([H])[C@@]1([H])OC2=C([H])C([H])=C([H])C([H])=C2OC1([H])[H]
[H]N(C(=O)C1=C([H])C(F)=C([H])C([H])=C1[H])[C@@]1([H])C([H])([H])N(C([H])([H])C([H])([H])C1([H])[H])C1([H])C([H])([H])C([H])([H])N(C(=O)OC([H])([H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]OC(=O)C1=C(SC2=C([H])C(OC([H])([H])[H])=C([H])C([H])=C2[H])C2=C([H])C3=C(OC([H])([H])O3)C([H])=C2N1C([H])([H])C1=C([H])C([H])=C2OC([H])([H])OC2=C1[H]
[H]N([H])C1=NC(=NC2=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C([H])=C12)N1C([H])([H])C([H])([H])N(C(=O)[C@@]([H])(OC2=C(C([H])=C([H])C([H])=C2OC([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]OC([H])([H])C([H])([H])N(C([H])([H])C([H])([H])O[H])C1([H])C([H])([H])C([H])([H])N(N([H])C(=O)OC2(C([H])([H])C2([H])[H])[C@]2([H])N(C([H])([H])S(=O)(=O)C3=C([H])C(F)=C(C([H])=C3[H])C([H])([H])[H])[C@@]([H])(C3=C([H])C([H])=C([H])C(F)=C3[H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]OC1=C2O[C@@]3([H])C(=O)C([H])([H])C([H])([H])[C@@]4(O[H])[C@]([H])(N(C([H])([H])[H])C([H])([H])C5([H])C([H])([H])C5([H])[H])C([H])([H])C(C([H])=C1[H])=C2[C@@]34C([H])([H])C([H])([H])[H]
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[H]N([H])C1=NC(=NC2=C(C([H])=C(C([H])=C12)C([H])([H])[H])C(=O)N([H])C1=C([H])C([H])=NN1[H])C([H])([H])[H]
[H]N(C(=O)C(\[H])=C(/[H])C(=O)N([H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C1=NC([H])=C2N=C([H])N=C(N([H])C3=C([H])C(Cl)=C(F)C([H])=C3[H])C2=C1[H]
[H]N(C([H])([H])C1=NN(C(=C1C([H])([H])[H])C1=C([H])N=C(C(F)=C1[H])C([H])([H])[H])C1=C(Cl)C([H])=C([H])C([H])=N1)[C@@]1([H])C([H])([H])C([H])([H])[C@@]([H])(F)C1([H])[H]
[H]N([H])C1=C2C(SC(=C2C2=C([H])C([H])=C(N([H])C(=O)N([H])C3=C([H])C(=C([H])C(=C3[H])C([H])([H])[H])C([H])([H])[H])C([H])=C2[H])C([H])([H])[H])=NC([H])=N1
CC1(C)CCC2=C(N=C3SC4=C(NCC5=CC=CN=C5)N=CN=C4C3=C2C1)N1CCOCC1
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[H]N(C(=O)C([H])([H])N1C([H])([H])C([H])([H])[C@@]([H])(N([H])C(=O)C([H])(C([H])([H])[H])C([H])([H])[H])C1([H])[H])C1=C([H])C([H])=C(SC2=NN3C([H])=C([H])C([H])=C3C(=N2)N([H])C2=NN([H])C(=C2[H])C([H])([H])[H])C([H])=C1[H]
[H]N(C(=O)C1=C([H])C(C#CN2C([H])=NC3=C2N=C([H])N=C3N([H])C2([H])C([H])([H])C2([H])[H])=C(C([H])=C1[H])C([H])([H])[H])C1=C([H])C(=C([H])C([H])=N1)C(F)(F)F
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[H]C([H])=C(C1=C([H])C(=C([H])C([H])=C1[H])C(N([H])C(=O)N([H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H]
[H]N=C(N([H])[H])C1=C([H])C(\C([H])=C(\C(=O)OC([H])([H])[H])C(=O)N([H])C2=C([H])C([H])=C(C([H])=C2[H])C2=C([H])C([H])=C([H])C([H])=C2S(=O)(=O)N([H])[H])=C([H])C([H])=C1[H]
[H]OC(=O)[C@]1([H])N(C(=O)[C@@](N([H])C(=O)O[C@@]2([H])[C@@]3([H])C([H])([H])[C@]4([H])C([H])([H])[C@]([H])(C3([H])[H])C([H])([H])[C@@]2([H])C4([H])[H])(C([H])([H])[H])C([H])([H])C2=C([H])N([H])C3=C2C([H])=C([H])C([H])=C3[H])C([H])([H])[C@]([H])(OC2=C([H])C([H])=C(F)C([H])=C2F)C1([H])[H]
[H]N([H])C(=O)N(C1=C2N=C([H])N(C2=NC(=N1)C1=C([H])C(Cl)=C([H])C([H])=C1[H])C([H])([H])[H])C1=C(F)C([H])=C([H])C([H])=C1F
[H]OC1=C(OC([H])([H])C([H])([H])[H])C([H])=C(C([H])=C1[H])[C@]1([H])C2=C(N([H])N=C2OC(N([H])[H])=C1C#N)C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])[C@]1([H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])[H])C([H])([H])[C@@]1([H])C(=O)OC1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
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[H]N([H])C1=C(C([H])=C(C(=C1[H])C(F)(F)F)S(=O)(=O)N([H])[H])S(=O)(=O)N([H])[H]
[H]N(C(=O)N([H])C1=C([H])C(C2=C([H])C([H])=NN2C([H])([H])[H])=C(OC([H])([H])C([H])([H])C([H])([H])N2C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])C([H])=C1[H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]N([H])C([H])([H])[C@]1([H])C([H])([H])[C@@]1(C(=O)N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H])C1=C([H])SC2=C1C([H])=C([H])C([H])=C2[H]
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[H]N(C1=NN([H])C2=NC(N3C([H])([H])C([H])([H])C([H])([H])C([H])([H])C3([H])[H])=C3C(=C12)C([H])([H])C([H])([H])N(C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C3([H])[H])C([H])([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
COC1=CC2=C(CN(C[C@]3(CC(=O)NC3=O)C#CC3=CC=C(C=C3)C(=O)N3CCC(CC3)N3CCCCC3)C2=O)C=C1
[H]N(C(=O)C1=C2N=C(N([H])C2=NC([H])=C1[H])N1C([H])([H])C([H])([H])[C@@]([H])(C2=C([H])C([H])=C([H])C([H])=C2[H])C1([H])[H])C1=C([H])N=C([H])C([H])=C1C([H])([H])[H]
[H]OC1([H])C([H])([H])C([H])([H])N(C(=O)[C@]([H])(N([H])S(=O)(=O)C2=C3N([H])C([H])([H])[C@]([H])(C([H])([H])[H])C([H])([H])C3=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C([H])([H])N=C(N([H])[H])N([H])[H])C([H])([H])C1([H])[H]
[H]OC1=C(OC([H])([H])[H])C([H])=C(\C([H])=C(/C#N)C(=O)N([H])[H])C([H])=C1C([H])([H])SC1=C([H])C([H])=C([H])C([H])=C1N([H])C(=O)C([H])([H])[H]
[H]N(C(=O)OC([H])([H])[H])C([H])([H])[C@@]1([H])C([H])([H])C([H])([H])[C@](C2=C(F)C([H])=C([H])C(F)=C2[H])(C([H])([H])C1([H])[H])S(=O)(=O)C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]N([H])C1=C([H])C(=NN1C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H])C1=C([H])C([H])=C(N([H])S(=O)(=O)C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])=C1[H]
[H]N(C(=O)OC([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)C([H])([H])SC([H])([H])C(=O)OC([H])([H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]\C(=C(\[H])C1=C([H])C([H])=C([H])C([H])=C1[H])N1C2=C(C([H])=C([H])C([H])=C2[H])[C@@]2([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C([H])([H])[C@@]12[H]
[H]OC(=O)[C@@]12C([H])([H])[C@]3([H])C([H])([H])[C@]([H])(C1([H])[H])[C@]([H])(N([H])C(=O)C(OC1=C([H])C([H])=C([H])C([H])=C1Cl)(C([H])([H])[H])C([H])([H])[H])[C@]([H])(C3([H])[H])C2([H])[H]
[H]N1N(C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])[C@]([H])(SC([H])([H])C([H])([H])[H])C1=O
[H]O\N=C1\C(\N([H])C2=C\1C([H])=C([H])C([H])=C2[H])=C1\C(=O)N([H])C2=C([H])C(Cl)=C(Cl)C([H])=C12
[H]N([H])C1=C(C([H])=NN1C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C(=O)N([H])C1=C(C([H])=C([H])C(=C1[H])C(=O)N([H])C1=C([H])C([H])=NN1C([H])([H])[H])C([H])([H])[H]
CNC1=NC(CC(F)(F)F)=C(S1)C1=CC=NC(NC2=CC=C(O)C=C2)=N1
[H]OC(=O)C([H])([H])C([H])([H])N([H])C(=O)C([H])([H])[C@@]1([H])O[C@]([H])(C2=C(OC([H])([H])[H])C(OC([H])([H])[H])=C([H])C([H])=C2[H])C2=C(C([H])=C([H])C(Cl)=C2[H])N(C1=O)C([H])([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])O[H]
[H]OC([H])([H])C1=C([H])C([H])=C([H])C(OC([H])([H])C([H])([H])C([H])([H])N2C([H])=NC(=C2C([H])([H])[H])C2=C([H])C([H])=C([H])C([H])=C2[H])=C1N([H])C(=O)N([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]OC(=O)C([H])([H])[C@]([H])(N([H])C(=O)C(\[H])=C(/[H])[C@@]1([H])O[C@@]([H])(N2N=NC3=C2N=C(SC([H])([H])C([H])([H])C([H])([H])[H])N=C3N([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])[C@]([H])(O[H])[C@]1([H])O[H])C(=O)O[H]
[H]N(C([H])([H])[H])C([H])([H])C([H])([H])[C@@]([H])(N1C(=O)N(C2=C1C(F)=C([H])C([H])=C2[H])C([H])(C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC(=O)C([H])([H])N1C(=S)S\C(=C(\[H])C2=C([H])C([H])=C(C([H])=C2[H])C2=C([H])C([H])=C([H])C([H])=C2[H])C1=O
[H]N1C([H])=NC(=C1C([H])([H])[H])[C@]1([H])[C@@]([H])(C2=C([H])C(Cl)=C([H])C(Cl)=C2[H])C1(C([H])([H])[H])C([H])([H])[H]
[H]ON([H])C(=O)C(\[H])=C(/[H])C1=C([H])C([H])=C2N(C(=NC2=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H]
[H]N(C(=O)C(OC1=C([H])C([H])=C(Cl)C([H])=N1)(C([H])([H])[H])C([H])([H])[H])[C@@]([H])(C([H])([H])[H])[C@]([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])N1C(=O)N(C(=O)C1([H])[H])S(=O)(=O)C1=C([H])C(=C([H])C([H])=C1[H])C([H])([H])C(=O)OC([H])([H])[H]
[H]N1[C@@]2([H])C3=C(N(C4=C([H])C([H])=C(C([H])=C34)S(=O)(=O)N3C4=C(C([H])=C([H])C([H])=C4[H])C4=C3C([H])([H])C([H])([H])C4([H])[H])C([H])([H])[H])C([H])([H])[C@]1([H])C([H])([H])C2([H])[H]
[H]ON([H])C(=N[H])C1=C([H])C([H])=C(C([H])=C1[H])C(=O)N([H])C1=C(C([H])=C([H])C([H])=C1[H])C(=O)N([H])C1=C([H])C([H])=C(Cl)C([H])=N1
[H]C1=C([H])C(=C([H])C([H])=C1Cl)C(=O)C([H])([H])C([H])([H])C(=O)N1C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]C1=C([H])C2=C([H])C([H])=C([H])[N+](=C2C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[N+]1=C([H])C([H])=C([H])C2=C([H])C([H])=C([H])C([H])=C12
[H]ON([H])C(=O)[C@]1([H])N(C([H])([H])C([H])([H])C2=C([H])C(O[H])=C(OC([H])([H])[H])C([H])=C12)S(=O)(=O)C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]N(C(=O)C([H])([H])OC([H])([H])C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC2=C([H])C(C#N)=C([H])C([H])=C2O1
[H]N1C(=O)\C(=C(\[H])C2=C(C(=C(N2[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])N2C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])C([H])([H])[H])C2=C1C([H])=C([H])C(=C2[H])S(=O)(=O)N(C1=C([H])C([H])=C([H])C(Cl)=C1[H])C([H])([H])[H]
[H]N(C(=O)C1=NC([H])=C([H])N=C1[H])C([H])([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])N(C1=NS(=O)(=O)C2=C([H])C(F)=C([H])C([H])=C12)C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N=C(N([H])[H])N([H])C([H])([H])C([H])([H])C([H])([H])[C@]([H])(N([H])[H])C(=O)N([H])[C@@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H]
[H]OC(=O)[C@@]([H])(N1C([H])([H])C([H])([H])C([H])(C2=C([H])N([H])C3=C([H])C([H])=C([H])C([H])=C23)C([H])([H])C1([H])[H])C1([H])C([H])([H])C([H])([H])N(C(=O)C(\[H])=C(/[H])C2=C([H])C([H])=C(C([H])=C2[H])[N+]([O-])=O)C([H])([H])C1([H])[H]
[H]OC(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])OC1=C([H])C([H])=C(N([H])C(=O)C2=C(O[H])C3=C([H])C(=C([H])C([H])=C3N=C2O[H])C2=C([H])C3=C([H])C([H])=C([H])C([H])=C3C([H])=C2[H])C([H])=C1[H]
[H]C1=C([H])C(=C([H])C([H])=C1Cl)C1=C(C2=C([H])C([H])=C(C([H])=C2[H])S(=O)(=O)C([H])([H])[H])C([H])([H])C2(C([H])([H])C2([H])[H])C1([H])[H]
[H]OC1=C(Br)C([H])=C(\C([H])=C(/[H])C(=O)C2=C([H])C([H])=C(OC(=O)C3=C([H])C([H])=C(C([H])=C3[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])=C2[H])C(OC([H])([H])[H])=C1[H]
[H]O[C@]1([H])C([H])([H])C2=C([H])C([H])([H])[C@@]3([H])[C@]4([H])C([H])([H])C([H])([H])[C@]([H])(C5=C([H])N([H])C(=N5)C5=C([H])C([H])=C([H])C([H])=C5[H])[C@@]4(C([H])([H])[H])C([H])([H])C([H])([H])[C@]3([H])[C@@]2(C([H])([H])[H])C([H])([H])C1([H])[H]
COC1=CC=C(NC2=NC(=CN3C=CN=C23)C2=NN(C)C=C2)C=C1
[H]N1C(=O)N(C2=C([H])C([H])=C([H])C([H])=C12)C1([H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])C([H])(C2=C([H])C([H])=C(F)C([H])=C2[H])C2=C([H])C([H])=C(F)C([H])=C2[H])C([H])([H])C1([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[N+](C([H])([H])[H])(C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])S([O-])(=O)=O
[H]N([H])C(=O)C(=O)C1=C(N(C2=C3C([H])=C([H])C([H])=C([H])C3=C([H])C(OC([H])([H])C(=O)OC([H])([H])[H])=C12)C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])[H]
[H]OC1(C2=C([H])C([H])=C(Cl)C([H])=C2[H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C(C#N)(C2=C([H])C([H])=C([H])C([H])=C2[H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]OC(=O)C([H])([H])[C@@]([H])(C1=C([H])C(Cl)=C([H])C(Cl)=C1[H])C([H])([H])C(=O)N([H])N([H])C(=O)C1=C([H])C(N([H])C(=N[H])N([H])[H])=C([H])C([H])=C1[H]
[H]C1=C(OC2([H])C([H])([H])C([H])([H])N(C(=O)OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C2([H])[H])C([H])=C2C(OC3(C([H])([H])C([H])([H])N(C([H])([H])C3([H])[H])C3([H])C([H])([H])C([H])([H])C3([H])[H])C([H])([H])C2([H])[H])=C1[H]
[H]OC(=O)[C@]([H])(N([H])S(=O)(=O)C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C(=O)N1C2=C([H])C([H])=C([H])C([H])=C2C([H])([H])[C@@]1([H])C(=O)O[H]
[H]C1=C([H])C(=C([H])C(OC([H])([H])[H])=C1OC([H])([H])[H])S(=O)(=O)N(C1=C([H])C(=C([H])C([H])=C1Cl)N1C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C(=O)N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H]
[H]N(C1=NC([H])([H])C2=C1C([H])([H])N(C(=O)N([H])[C@@]1([H])C([H])([H])[C@]1([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C2(C([H])([H])[H])C([H])([H])[H])C1=NC(=NC(=N1)N1C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])[H]
[H]N(C([H])([H])C(=O)N1C([H])([H])[C@@]([H])(F)C([H])([H])[C@@]1([H])C#N)C(C1=C([H])C([H])=C([H])S1)(C([H])([H])[H])C([H])([H])[H]
[H]OC1=C(C([H])=C([H])C(N([H])C([H])([H])C2=NC3=C(SC4=C([H])C([H])=C(Cl)C([H])=C34)C(=O)N2[H])=C1[H])C([H])([H])[H]
[H]N(C(=O)[C@@]1([H])C([H])([H])[C@]1([H])C([H])([H])OC1=C([H])C(=C([H])C(=C1[H])C([H])([H])C([H])([H])C([H])([H])OC([H])([H])[H])C([H])([H])N(C(=O)[C@@]1([H])C([H])([H])N([H])C([H])([H])C([H])([H])[C@]1([H])C1=C([H])C([H])=C(OC([H])([H])C([H])([H])OC2=C(Cl)C([H])=C(C([H])=C2Cl)C([H])([H])[H])C([H])=C1[H])C1([H])C([H])([H])C1([H])[H])S(=O)(=O)C([H])([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])[C@@]([H])(C([H])([H])N1[C@@]2([H])C([H])([H])C([H])([H])[C@]1([H])C([H])([H])[C@@]([H])(OC([H])(C1=C([H])C([H])=C(F)C([H])=C1[H])C1=C([H])C([H])=C(F)C([H])=C1[H])C2([H])[H])C([H])([H])C([H])([H])[H]
[H]N(C(=O)C([H])([H])C1=C(OC(=N1)C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H])C1=C([H])C2=C(N=C(C([H])=C2C([H])([H])[H])N(C([H])([H])[H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H])C([H])=C1[H]
[H]C1=C(C(=O)C2=C([H])C([H])=C3N=C([H])C([H])=C([H])C3=C2[H])C2=C([H])C([H])=C([H])C([H])=C2N1C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]N1C(=NN(C2=C(Br)C([H])=C([H])C([H])=C2[H])[S@]1=O)C1=C([H])C([H])=C([H])C([H])=C1C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1C2=NC(=C([H])C(=C2N=C1C([H])([H])C([H])([H])[H])C([H])([H])[H])C([H])([H])[H]
[H]N([H])[C@@]([H])(C([H])([H])C(=O)N1C([H])([H])C([H])([H])C2=C(N=C([H])N2C([H])([H])[H])[C@]1([H])C(F)(F)F)C([H])([H])C1=C(F)C([H])=C(F)C(F)=C1[H]
[H]N(C(=O)C([H])([H])[H])C1=C([H])C(=C([H])C([H])=C1[H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])N2C(=NC3=C([H])C([H])=C([H])C([H])=C23)C2=C([H])C([H])=C(Cl)C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N(C1=NC(=C([H])S1)C1=NC([H])=C([H])C([H])=C1[H])C([H])([H])[C@]1([H])[C@]2([H])C([H])([H])N(C(=O)C([H])([H])C3=C([H])C([H])=C([H])C([H])=C3[H])C([H])([H])[C@]12[H]
CCC(OC1=CC=C([Se]CC2=C(C)N=C(S2)C2=CC=C(C=C2)C(F)(F)F)C=C1C)C(O)=O
[H]O[C@]([H])(C([H])([H])N([H])C(=O)C1=C(N(C(=N1)C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])C([H])([H])[H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C([H])C([H])=C([H])C(=C2C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H]
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[H]N([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
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[H]N([H])C1=C(C(=O)C2=C([H])C([H])=C(Cl)C([H])=C2[H])C2=C(S1)C([H])([H])C([H])([H])C([H])([H])C2([H])[H]
[H]N1C([H])=C(C2=C([H])C(=C([H])C([H])=C12)N1C([H])=NN=C1[H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
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[H]N([H])C1=C(N=C([H])C([H])=C1[H])C1=C([H])C(=C([H])C(F)=C1[H])N1N=NC(=N1)C1=C([H])C([H])=C([H])C([H])=N1
[H]OC(=O)C1=C([H])C(Cl)=C([H])C([H])=C1N([H])C(=O)C1=C([H])C([H])=C([H])C(O[H])=C1[H]
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[H]C1=NC(=C([H])C([H])=N1)C(=O)N1C([H])([H])C([H])([H])C2(C([H])([H])C1([H])[H])C([H])([H])C([H])([H])N(C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1OC1=C(OC([H])([H])[H])C([H])=C([H])C([H])=C1[H])C([H])([H])C2([H])[H]
[H]OC1=C([H])C([H])=C2N=C(SC2=C1[H])N([H])C(=O)C1=C([H])C(O[H])=C([H])C(O[H])=C1[H]
[H]N(C(=O)C1=C([H])C([H])=C(Br)O1)C1=C([H])C([H])=C([H])C(Cl)=C1N1C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[C@@]1([H])N(C(=O)OC([H])([H])[H])C([H])([H])C([H])=C([H])C1=O
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[H]N(C([H])([H])C(\[H])=C(/C([H])([H])[H])C([H])([H])C([H])([H])C(\[H])=C(/C([H])([H])[H])C([H])([H])C([H])([H])C([H])=C(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])[H]
[H]N(C1=NN([H])C(=C1[H])C([H])([H])[H])C1=C(N=C(C#N)C(=N1)N([H])[C@]([H])(C1=NC([H])=C(F)C([H])=N1)C([H])([H])[H])C([H])([H])[H]
[H]N([H])C1=C([H])C(=NC2=C([H])C([H])=C(N([H])C(=O)C3=C([H])C([H])=C([H])C([H])=C3C([H])([H])OC3=C([H])C([H])=C(C([H])=C3[H])C([H])([H])N([H])[H])C([H])=C12)C([H])([H])[H]
[H]N(C(=O)[C@@]([H])(N([H])C(=O)C([H])([H])C1=C([H])N=C([H])N1[H])C([H])([H])OC([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C(OC2([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])=C1[H]
[H]N(C(=S)N([H])C([H])([H])C([H])([H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H])C(=O)C1=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]N1C([H])=C([H])C2=NC(=C([H])C2=C1[H])C([H])([H])N1C(=O)C([H])([H])N(C([H])([H])C1([H])[H])S(=O)(=O)C1=C([H])C([H])=C(S1)C1=C([H])C([H])=C(Cl)S1
[H]N(C(=O)C([H])([H])N(C([H])([H])C1=C([H])C([H])=C(F)C([H])=C1[H])C([H])([H])C([H])([H])OC1=C([H])C([H])=C(OC([H])([H])[H])C(OC([H])([H])[H])=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC1=C2C([H])=C([H])C([H])=C([H])C2=C2C(=N1)C([H])([H])N(C(=O)C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C2([H])[H]
OC1=CC=C(C=C1)[C]1234[B]567[B]89%10[B]55%11[B]88%12[B]99%13[B]16%10[B]291[B]323[B]58([B]47%112)[C]%12%1313
[H]N(C(=O)C([H])([H])[H])C1=C([H])C([H])=C2C(N([H])C(=O)\C2=C(/N([H])C2=C([H])C([H])=C(C([H])=C2[H])C([H])([H])N2C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C2=C([H])C([H])=C([H])C([H])=C2[H])=C1[H]
[H]OC([H])([H])[C@@]1([H])S[C@@]([H])(C2=C(OC([H])([H])[H])C([H])=C([H])C(=C2[H])C([H])([H])C2=C([H])C([H])=C(OC([H])([H])C([H])([H])[H])C([H])=C2[H])[C@]([H])(O[H])[C@@]([H])(O[H])[C@]1([H])O[H]
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[H]\C(=C(\[H])C1=C([H])C([H])=C(SC2=C([H])C(OC3([H])C([H])([H])C([H])([H])SC([H])([H])C3([H])[H])=C([H])C([H])=C2[H])C(=C1C(F)(F)F)C(F)(F)F)C(=O)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]\C(=N/OC([H])([H])[H])C1(C2=C([H])C([H])=C([H])C(SC3=C([H])C([H])=C(C([H])=C3[H])N3C([H])=C([H])N=C3C([H])([H])[H])=C2[H])C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]OC(=O)[C@@]([H])(N([H])S(=O)(=O)C1=C(C([H])=C([H])C([H])=C1Cl)C([H])([H])[H])C([H])([H])N([H])C(=O)C1=NO[C@@]([H])(C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])C2=NC([H])=C([H])N2[H])C1([H])[H]
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