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[H]N=C(N([H])[H])N([H])C([H])([H])C([H])([H])C([H])([H])[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C([H])([H])C(=O)OC1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=N[H])N([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])C(=O)N([H])C1([H])C([H])([H])C([H])([H])N(C(=N[H])N([H])[H])C([H])([H])C1([H])[H]
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[H]N(C(=O)C1=C([H])C(=C([H])C([H])=C1[H])C(F)(F)F)C1=C([H])C([H])=C([H])C(=C1[H])C1=C([H])C([H])=NC2=C(C([H])=NN12)C1=C([H])C([H])=C(N=C1[H])N([H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H]
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[H]N([H])C1=C2C(SC([H])=C2C2=C([H])C([H])=C(N([H])C(=O)N([H])C3=C([H])C([H])=C([H])C(=C3[H])C([H])([H])[H])C(F)=C2[H])=NC([H])=N1
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[H]OC([H])([H])C([H])([H])N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])OC1=C([H])C2=NC([H])=NC(N([H])C3=C([H])N(N=C3[H])C([H])([H])C(=O)N([H])C3=C([H])C(F)=C([H])C([H])=C3[H])=C2C([H])=C1OC([H])([H])[H]
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[H]N1C(=O)\C(=C(\[H])C(=O)C(\[H])=C2/C(=O)N([H])C3=C([H])C([H])=C([H])C([H])=C23)C2=C([H])C([H])=C([H])C([H])=C12
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[H]N(C(=O)C1=C([H])N(C2=C([H])C([H])=C(C([H])=C2C1=O)C1=C(F)C([H])=C(F)C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])[C@]12C([H])([H])[C@@]3([H])C([H])([H])[C@]([H])(C([H])([H])[C@]([H])(C3([H])[H])C1([H])[H])C2([H])[H]
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[H]N(C1=C2C([H])=C([H])C(Cl)=C([H])C2=NC2=C1C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C([H])([H])C([H])([H])N([H])C([H])([H])C([H])([H])C([H])([H])OC1=C([H])C([H])=C([H])C2=C1C1=C(N2[H])C([H])=C([H])C([H])=C1[H]
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[H]N=C(N([H])[H])C1=C([H])C([H])=C([H])C(=C1[H])C([H])([H])N1C(=C([H])C2=C([H])C([H])=C([H])C([H])=C12)C(=O)N([H])C([H])([H])C1=C([H])C(=C([H])C([H])=C1[H])C(=O)N([H])[H]
[H]N(C1=NN2C([H])=C([H])C([H])=C(N([H])C([H])([H])C3=C([H])C([H])=C([H])C(=C3[H])N(C([H])([H])[H])S(=O)(=O)C([H])([H])[H])C2=N1)C1=C([H])C([H])=C(C([H])=C1[H])N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C(N([H])C(=O)C([H])(C([H])([H])[H])C([H])([H])[H])C([H])=C1[H])C1=NC([H])=C([H])S1
[H]OC(=O)C([H])([H])C([H])([H])[C@@]1(OC2=C([H])C(OC([H])([H])C3=C([H])C(OC([H])([H])C4=NC5=C([H])C([H])=C([H])C([H])=C5C([H])=C4[H])=C([H])C([H])=C3[H])=C([H])C([H])=C2C(=O)C1([H])[H])C([H])([H])[H]
[H]N1C(=N[C@](C2=C([H])C([H])=C(F)N=C2[H])(C2=C([H])C([H])=C(F)C([H])=C2[H])[C@]1([H])C([H])([H])[H])C1=NSN=C1[H]
[H]N(C(=O)C([H])([H])N(C1=C(OC([H])([H])[H])C([H])=C([H])C(OC([H])([H])[H])=C1[H])S(=O)(=O)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=NC([H])=C1[H]
[H]C1=C(SC2=NC3=C(O2)C([H])=C([H])C(Cl)=C3[H])C2=C([H])C([H])=C([H])C([H])=C2S1(=O)=O
[H]OC(=O)C([H])([H])C([H])([H])[C@]([H])(N1C(=O)C2=C([H])C([H])=C(N([H])C([H])([H])C3=NC4=C(N=C(N=C4N=C3[H])N([H])[H])N([H])[H])C([H])=C2C1([H])[H])C(=O)O[H]
[H]N(C(=O)C([H])([H])C1=C([H])SC2=C1C([H])=C([H])C([H])=C2[H])[C@]1([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C(Cl)C(Cl)=C2[H])C([H])([H])C1([H])[H]
NC1=CC(=CC=C1)C1=NN=C2N1C1=CC=CN=C1NC1=C2C=CC=C1
[H]OC(=O)[C@]([H])(OC([H])([H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(OC([H])([H])C([H])([H])N2C([H])([H])C([H])=C(C3=C([H])C([H])=C([H])C([H])=C3C(F)(F)F)C([H])([H])C2([H])[H])C([H])=C1[H]
[H]N1C(C2=C([H])C([H])=C([H])C([H])=C2[H])=C(C(=O)OC([H])([H])C([H])([H])[H])[C@]([H])(C(C(=O)SC([H])([H])C([H])([H])[H])=C1C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]N(C(=O)C([H])([H])[H])C([H])([H])C([H])([H])SC(=S)SC([H])([H])C(=O)C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
COC1=CC(CN(C2CC2)C(=O)NC2=CC=C(C=C2)C2=CNN=C2)=CC=C1
[H]C1=C([H])C(C2=NN(C3=C2N=C(C([H])=C3N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])[H])=C(Cl)C([H])=C1Cl
[H]C1=NC([H])=C([H])C(=C1[H])C1=C([H])C2=C(N=C1[H])C([H])=C(Cl)C([H])=C2[H]
[H]OC1=C2C(=C([H])C([H])=C1[H])C([H])([H])[C@@]1([H])N(C([H])([H])C(\[H])=C(/[H])I)C([H])([H])C([H])([H])C([H])([H])[C@]1([H])C2([H])[H]
C[C@@H]1CN(CCN1C1=NC=C(OCC2=CC=C(C=C2)C#N)C=N1)C(=O)OC(C)(C)C
[H]OC(=O)C1=C([H])C(=C([H])C2=C([H])C([H])=C([H])C([H])=C12)N1C([H])([H])C([H])([H])N(C(=O)C2=C([H])N(C(=N2)C2=C([H])C([H])=C(C([H])=C2[H])C([H])([H])[H])C2=C([H])C(OC([H])([H])C([H])([H])[H])=C([H])C([H])=C2[H])[C@]([H])(C(=O)N([H])C([H])(C([H])([H])[H])C([H])([H])[H])C1([H])[H]
[H]N([H])S(=O)(=O)C1=C([H])C([H])=C(C([H])=C1[H])[N+]1=C(C([H])=C(C([H])=C1C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H]
[H]OC1=C(N([H])C2=C([H])C([H])=C([H])C(C(=O)N([H])C([H])([H])C3=C([H])C([H])=C([H])C([H])=C3[H])=C2O[H])\C(=N\C2=C([H])C([H])=C([H])C([H])=C2[H])C1=O
[H]N(C(=O)N1C([H])([H])C([H])([H])N(C2=NC([H])=NC3=C([H])C(OC([H])([H])C([H])([H])C([H])([H])N4N=NC([H])=C4[H])=C(OC([H])([H])[H])C([H])=C23)C([H])([H])C1([H])[H])C1=C([H])C([H])=C(OC([H])(C([H])([H])[H])C([H])([H])[H])C([H])=C1[H]
CC(=O)NC1=C(OC[C@@H](N)CN2CCC3(CC4=CC(F)=CC=C4O3)CC2)C=C(O)C=C1
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[H]N(C(=O)N([H])C([H])([H])C1(C2=C([H])C([H])=C(C([H])=C2[H])C2=C([H])C(C#N)=C([H])C([H])=C2[H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C(F)C(F)=C1[H]
[H]N([H])C1=NC(=C([H])C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])C1=NC(=C([H])N1[H])C([H])([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C([H])([H])[H]
[H]N(C(=O)C([H])([H])C([H])([H])N1C(=O)N([H])C(=O)C2=C1C([H])([H])C([H])([H])SC2([H])[H])C([H])([H])C(=O)N1C([H])([H])C([H])([H])N(C2=C([H])C(=C([H])C([H])=N2)C(F)(F)F)C([H])([H])C1([H])[H]
[H]N1C(=NC(C2=C([H])C([H])=C(F)C([H])=C2[H])(C2=C([H])C([H])=C(F)C([H])=C2[H])C1([H])[H])C1=C([H])C([H])=C([H])C(=C1[H])C(=O)OC([H])([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C(F)C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])N(C1=NS(=O)(=O)C2=C([H])C([H])=C([H])C([H])=C12)C1=C([H])C(F)=C([H])C([H])=C1[H]
[H]N(C1=NC(=NC(=N1)N(C([H])([H])[H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H])C1=C(C([H])=C(C([H])=C1C([H])([H])[H])C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)C([H])([H])N([H])C1=C([H])C([H])=C(Cl)C([H])=C1Cl)C1=C([H])C([H])=C2N=C(C([H])=C(C2=C1[H])C([H])([H])[H])N(C([H])([H])[H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C(O1)C1=C([H])C(Cl)=C([H])C([H])=C1Cl)C1=C(C([H])=C(C([H])=C1C([H])([H])[H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)C([H])([H])C([H])([H])C([H])([H])[H])C1=C([H])N=C2N(C(=NC2=C1C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1S(=O)(=O)N([H])C(=O)N([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]OC(=O)C1=C([H])C(=C(C([H])=C1[H])C([H])([H])[H])S(=O)(=O)N(C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])[H]
[H]N(C(=S)N([H])C1=C(N2C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C(Cl)=C([H])C([H])=C1[H])C(=O)C([H])([H])C([H])([H])C([H])([H])[H]
[H]OC(=O)C([H])([H])[C@]1([H])N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])[H])C([H])([H])C2=C([H])C([H])=C(O[H])C([H])=C2[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])[H])C([H])([H])SSC([H])([H])[C@]([H])(N([H])C(=O)[C@@]2([H])N(C1=O)C([H])([H])C([H])([H])C2([H])[H])C(=O)O[H]
[H]OP(=O)(O[H])OC([H])([H])[C@@]([H])(C([H])([H])O[P@@](=O)(O[H])OP(=O)(O[H])O[H])C([H])([H])N1C([H])=NC2=C(N=C(Cl)N=C12)N([H])C([H])([H])[H]
[H]N(N1C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C(OP(=O)(OC2=C([H])C([H])=C(N([H])N3C([H])([H])C([H])([H])C([H])([H])C3([H])[H])C([H])=C2[H])[C@]2([H])N(C(=O)[C@]3([H])C([H])([H])C([H])([H])C([H])([H])[N+]3([H])[H])C([H])([H])C([H])([H])C2([H])[H])C([H])=C1[H]
[H]N(C(=O)C1=NC([H])=C([H])C(Cl)=C1[H])[C@@]1([H])[C@@]([H])([N@]2C([H])([H])C([H])([H])[C@]1([H])C([H])([H])C2([H])[H])C([H])([H])C1=C([H])C([H])=C([H])N=C1[H]
[H]N(C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1C(=O)N([H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C3OC([H])([H])OC3=C2[H])C([H])([H])C1([H])[H])C([H])([H])C1=NC([H])=C([H])N1[H]
[H]N(C1=NC2=C(S1)C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C21)C1=C([H])C([H])=C([H])C([H])=C1F
[H]O[C@]([H])(C1=C([H])C([H])=C([H])N=C1[H])C([H])([H])N([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C(N([H])C(\N([H])C2=C3C([H])=C([H])C([H])=C([H])C3=C([H])C([H])=C2[H])=C(\[H])[N+]([O-])=O)C([H])=C1[H]
[H]N(C(=O)C1=C([H])N=C([H])N(C1=O)C([H])([H])C1=C([H])C([H])=C(F)C(F)=C1[H])C([H])([H])C#CC1=C([H])C2=C(N=C([H])N=C2C([H])=C1[H])N([H])C([H])([H])C([H])([H])C1=NC([H])=C([H])C([H])=C1[H]
[H]OC(=O)[C@]([H])(OC([H])([H])C([H])([H])C1=C2S[C@]([H])(C([H])([H])[H])C([H])([H])C3=C2C(=C([H])C([H])=C3OC([H])([H])C2=C([H])C([H])=C(C([H])=N2)C2=C([H])C([H])=C([H])C([H])=C2[H])N1C([H])([H])C1=C([H])C([H])=C(Cl)C([H])=C1[H])C([H])([H])C([H])([H])[H]
[H]OC(=O)[C@]1(OC2=C([H])C([H])=C(OC([H])([H])C([H])([H])C([H])([H])OC3=C([H])C([H])=C(OC(F)(F)F)C([H])=C3Cl)C([H])=C2C1([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C(C1=C([H])C([H])=C([H])C([H])=C1[H])=C1C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])OC2=C([H])C([H])=C3C(=O)C([H])=C(OC3=C2[H])C2([H])N=NN=N2)C([H])([H])C1([H])[H]
[H]OC(=O)C([H])([H])[C@]1([H])N([H])C(=O)C([H])([H])N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@](N([H])C(=O)[C@]([H])(N([H])C1=O)C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])(C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C(F)(F)F)C([H])([H])C([H])([H])C([H])([H])N([H])C(=N[H])N([H])[H]
[H]N1C([H])([H])[C@@]([H])(N2C([H])([H])C([H])([H])N(C3=NC4=C(O3)C([H])=C([H])C(C#N)=C4[H])C([H])([H])C2([H])[H])C([H])([H])[C@@]1([H])C(=O)N1C([H])([H])SC([H])([H])C1([H])[H]
[H]N(C1=C([H])C([H])=C(C([H])=C1[H])C(F)(F)F)C1=NC([H])=NC2=C1N=C(S2)N(C1=C(Cl)C([H])=C([H])C([H])=C1Cl)C([H])([H])[H]
[H]OC(=O)C1([H])C([H])([H])N(C([H])([H])C2=C([H])C(F)=C(C([H])=C2[H])C2=NC3=C([H])C([H])=C(C([H])=C3S2)[C@@]([H])(C2=NC([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])[H])C1([H])[H]
[H]OC(=O)C([H])([H])[C@]([H])(N([H])C(=O)C1=C([H])N=C(C([H])=C1[H])C([H])([H])N([H])S(=O)(=O)C1=C([H])C([H])=C([H])C(=C1[H])S(=O)(=O)N([H])C(=O)C([H])([H])[H])C([H])=O
[H]N(C(=O)C([H])([H])C([H])([H])C1=NC(=NO1)C1=C(Cl)C([H])=C(F)C([H])=C1[H])C1=C([H])N=C(N=C1[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]OC(=O)C([H])([H])C(=O)N([H])C1=C2C(=C(OC3=C([H])C(=C(O[H])C([H])=C3[H])C([H])(C([H])([H])[H])C([H])([H])[H])C(Br)=C1[H])C([H])([H])C([H])([H])C2([H])[H]
[H]OC(=O)[C@]([H])(N([H])S(=O)(=O)C1=C(Cl)C(Cl)=C([H])C([H])=C1[H])C([H])([H])N([H])C(=O)C1=C([H])SC([H])=C1[H]
[H]OC1=C([H])C([H])=C(C(=O)C([H])([H])OC2=C([H])C([H])=C([H])C([H])=C2Br)C(O[H])=C1[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C1=C(Cl)C(=O)C2=C([H])C(Cl)=C([H])C([H])=C2O1
[H]N([H])C1=C([H])C(N([H])S(=O)(=O)C2=C([H])C([H])=C([H])C([H])=C2[H])=C([H])C([H])=C1[H]
[H]OC1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[C@@]([H])(N([H])[H])C(=O)N1C(=O)[C@]([H])(N([H])C(=O)[C@]([H])(N([H])C(=O)[C@@]1([H])C([H])([H])S[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C(S[H])(C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C(=O)C([H])([H])C([H])([H])C1=NN=C(O1)C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
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[H]N(C1=C(Cl)C(=NO1)C([H])([H])[H])S(=O)(=O)C1=C(SC([H])=C1[H])C(=O)C([H])([H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]N([H])C([H])([H])C1=C([H])C2=C(C([H])=C1[H])C1=C(N2[H])C2=C(C3=C4N2C([H])([H])C([H])([H])C([H])([H])C4=C([H])C([H])=C3[H])C2=C1C(=O)N([H])C2=O
[H]OC([H])([H])[C@@]1([H])O[C@@]([H])(C2=C([H])C([H])=C(Cl)C(=C2[H])C([H])([H])C2=NC([H])=C(S2)C2=NN=C([H])S2)[C@]([H])(O[H])[C@@]([H])(O[H])[C@]1([H])O[H]
CC(C)(C)OC(=O)N1[C@H]2CC[C@H]1CC(C2)NC1=NC=NC(NC2=C(F)C=C(C=C2)S(C)(=O)=O)=C1[N+]([O-])=O
[H]N1C([H])([H])[C@@]2([H])C([H])=C(C3=C([H])N=C([H])C(OC4=C([H])C([H])=C(OC([H])([H])[H])C([H])=C4[H])=C3[H])C([H])([H])[C@@]([H])(C1([H])[H])C2([H])[H]