[H]N([H])[C@@]([H])(C([H])([H])C(=O)N1C([H])([H])C([H])([H])N([H])C(=O)[C@@]1([H])C([H])([H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C([H])([H])C1=C(F)C([H])=C(F)C(F)=C1[H]
[H]N(C(=O)C1=C(N(C(=C1[H])C1=C([H])N=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C([H])C([H])=C([H])C(Cl)=C2Cl)C([H])([H])C1([H])[H]
[H]N(C(=O)C1=NC(=NC([H])=C1Cl)S(=O)(=O)C([H])([H])C1=C([H])C([H])=C(F)C([H])=C1[H])C1=NN=C(S1)C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N=C(N(C1=C2C([H])=C([H])C([H])=C([H])C2=C([H])C([H])=C1[H])C([H])([H])[H])N(C1=C([H])C([H])=C([H])C2=C([H])C([H])=C([H])C([H])=C12)C([H])([H])C([H])([H])[H]
[H]C1=C([H])C([H])=C(O1)C(=O)OC1=C(N(C2=C([H])C([H])=C([H])C([H])=C12)C([H])([H])[H])C(=O)C([H])([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C(C([H])=C1[H])C(=O)N([H])S(=O)(=O)C1=C([H])C([H])=C(Cl)C([H])=C1[H])[C@]([H])(C(=O)N1C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C(=O)N([H])[C@]([H])(C(=O)C1=NC2=C(O1)C([H])=C([H])C(=C2[H])C(=O)OC([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H]
CN1CCc2c(Br)c(O)c(O)cc2C(C1)c1ccc(C)cc1
[H]N(C([H])([H])C1=C([H])N(C2=C([H])C([H])=C([H])C([H])=C2C1=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])[C@]1([H])C2=C(C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C1([H])[H]
[H]N1C([H])=NC2=C1C([H])=C([H])C([H])=C2C(=O)OC([H])([H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N1C([H])=C([H])C2=C(C([H])=C([H])C([H])=C2C1=O)C([H])([H])C1=NN=C2C([H])=C([H])C(=NN12)C1=C([H])N(N=C1[H])C1([H])C([H])([H])C([H])([H])N([H])C([H])([H])C1([H])[H]
[H]ON(C([H])=O)C([H])([H])C([H])([H])OC1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C(C#N)C([H])=C1[H]
[H]N(C(=O)C1=C(C([H])=C([H])C([H])=C1[H])N1C([H])=C([H])N=C1C([H])([H])C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C(=O)N(C1=C([H])C([H])=C(C([H])=C1OC([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C(=O)N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H])C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])C1=C2C(=NC3=C1C([H])=C([H])C(Cl)=C3[H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H]
[H]N([H])[C@@]([H])(C([H])([H])C(=O)N1C([H])([H])C([H])([H])N2C(=NN=C2C(F)(F)F)[C@@]1([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1F)C([H])([H])C1=C(F)C([H])=C(F)C(F)=C1[H]
[H]ON([H])C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)C1=C([H])C([H])=C([H])C2=C1C([H])=C([H])C([H])=C2[H]
C1[C@H](NN=C1C1=C2C=CC=CC2=CC2=CC=CC=C12)C1=CC=CC=N1
[H]N(C(=O)C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C(OC([H])([H])[H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H])C([H])([H])C1=NC2=C([H])C([H])=C(F)C([H])=C2C(=O)N1C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]N(OC([H])([H])C(=O)OC([H])([H])[H])C(=O)C([H])([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])C([H])([H])[H])C([H])([H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H]
Cc1cnc(N)nc1-c1c[nH]c(c1)C(=O)NCc1cccc(c1)C(F)(F)F
[H]OC1(C2=C([H])C([H])=C(Cl)C([H])=C2[H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])OC2=C([H])C([H])=C(F)C([H])=C2[H])C([H])([H])C1([H])[H]
[H]OC(=O)C([H])([H])C([H])([H])C1=C(C([H])=C(OC([H])([H])C([H])([H])C2=C(OC(=N2)C2=C([H])C([H])=C(OC3=C([H])C([H])=C([H])C([H])=C3[H])C([H])=C2[H])C([H])([H])[H])C([H])=C1[H])C([H])([H])N([H])C(=O)OC([H])(C([H])([H])[H])C([H])([H])[H]
[H]OC1=C([H])C([H])=C(C([H])=C1[H])C1=C(O[H])C(=O)C2=C(O[H])C([H])=C(O[H])C([H])=C2O1
[H]C1=C([H])C(=C([H])S1)N(C(=O)O[C@@]1([H])C([H])([H])[C@@]2([H])N(C([H])([H])[H])[C@]([H])(C([H])([H])C2([H])[H])C1([H])[H])C([H])([H])C1=C([H])SC([H])=C1[H]
[H]ON([H])C(=O)C(\[H])=C(/[H])C1=C([H])C2=C(C([H])=C1[H])C([H])([H])N(C2=O)C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)C1=C([H])C([H])=C(OC([H])([H])C2=C([H])C(=NC3=C([H])C([H])=C([H])C([H])=C23)C([H])([H])[H])C([H])=C1[H])C1(C([H])([H])C2=NN([H])C(=S)N2[H])C([H])([H])C([H])([H])N(C(=O)OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N(C(=O)[C@@]1([H])C([H])([H])C([H])([H])[C@@]2([H])[C@@]3([H])C([H])([H])C([H])([H])[C@]4([H])N([H])C(=O)C([H])=C([H])[C@]4(C([H])([H])[H])[C@@]3([H])C([H])([H])C([H])([H])[C@]12C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC(=O)C1=C([H])C([H])=C(C([H])=C1[H])C1=NC(OC([H])([H])C([H])([H])OC([H])([H])C([H])([H])C([H])([H])[H])=C(S1)C([H])([H])[H]
[H]N(C(=O)C1=C([H])C2=C(O1)C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C([H])([H])OC1=C(OC([H])([H])[H])C([H])=C([H])C2=C([H])C3=[N+](C([H])=C12)C([H])([H])C([H])([H])C1=C([H])C2=C(OC([H])([H])O2)C([H])=C31
[H]N1C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C1([H])[H])S(=O)(=O)C1=C([H])C([H])=C([H])C2=C1C([H])=C([H])N=C2[H]
[H]N1C([H])=C(C2=C1C([H])=C([H])C(C#N)=C2[H])[C@@]1([H])C([H])([H])C([H])([H])[C@]([H])(N2C([H])([H])C([H])([H])N(C3=C4N=C([H])C([H])=NC4=C([H])C([H])=C3[H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]N([H])C1=NC2=C([H])C(Cl)=C([H])C([H])=C2N2C1=NN=C2C([H])([H])C([H])([H])[H]
[H]OC(=O)C([H])([H])C([H])([H])[C@@]([H])(N([H])C(=O)C1=C([H])C([H])=C(S1)N(C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C2N=C(N=C(O[H])C2=C1[H])N([H])[H])C(=O)O[H]
[H]N([H])C1=NC2=C(C([H])=C(C([H])=C2[H])C2=C(N=C(N2[H])C2=C(F)C([H])=C([H])C([H])=C2F)C2=C([H])C([H])=C([H])C([H])=C2[H])N1C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]ON([H])C(=O)[C@]1([H])N(C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2C1([H])[H])[P@](=O)(OC([H])([H])C([H])([H])[H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]OC(=O)C([H])([H])C([H])([H])C(\[H])=C(\[H])C([H])([H])[C@]1([H])C([H])([H])O[C@]([H])(O[C@@]1([H])C1=C([H])N=C([H])C([H])=C1[H])C(OC1=C([H])C([H])=C(C([H])=C1[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]N([H])C1=C(C([H])=C([H])C(Cl)=C1[H])C([H])([H])N1C(=O)C2=C([H])C(I)=C([H])C([H])=C2N(C(=O)[C@]1([H])C1=C([H])C([H])=C(Cl)C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]OC(=O)C([H])([H])C([H])([H])[C@]([H])(N([H])C(=O)C1=C([H])C([H])=C(C([H])=C1[H])N(C([H])([H])C1=C([H])C2=C(N=C(N=C2O[H])C([H])([H])O[H])C([H])=C1[H])C([H])([H])C([H])([H])[H])C(=O)O[H]
[H]N(C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])[C@@]([H])(C([H])([H])[H])C([H])([H])N1C(=O)N(C(=C(C1=O)C1=C([H])C([H])=C([H])C(OC([H])([H])[H])=C1F)C([H])([H])[H])C([H])([H])C1=C(F)C([H])=C([H])C([H])=C1F
[H]OC(=O)[C@@]([H])(N([H])S(=O)(=O)C1=C([H])C([H])=C2C(OC3=C2C([H])=C(C([H])=C3[H])N2N=C([H])N=C2[H])=C1[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]OC(=O)C1([H])C([H])([H])C([H])([H])N(C(=O)C(\[H])=C(/[H])C2=C([H])C([H])=C(SC3=C([H])C4=C(OC([H])([H])C([H])([H])O4)C([H])=C3[H])C(=C2[H])C(F)(F)F)C([H])([H])C1([H])[H]
[H]N([H])[C@@]([H])(C([H])([H])C(=O)N1N(C(=O)N([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C1=C(F)C([H])=C(F)C(F)=C1[H]
[H]OC1(C2=C([H])C([H])=C(Cl)C([H])=C2[H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])C2(C#N)C3=C(C([H])=C([H])C([H])=C3[H])C([H])([H])C([H])([H])C3=C2C([H])=C([H])C([H])=C3[H])C([H])([H])C1([H])[H]
[H]N(C(=O)C1=C2N=C(OC2=C([H])C([H])=C1[H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C1([H])C([H])([H])[C@]2([H])N(C([H])([H])[H])[C@]([H])(C([H])([H])C([H])([H])C2([H])[H])C1([H])[H]
[H]N(C(=O)OC([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])[C@]([H])(C(=O)N([H])[C@]1([H])C(=O)N2C([H])([H])C([H])([H])S(=O)(=O)[C@]12[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)C1=NC([H])=C(\C([H])=C(/[H])C(=O)N([H])C([H])([H])C(=O)N(C2=C([H])C([H])=C(Cl)C(=C2Cl)C([H])([H])OC2=C3N=C(C([H])=C(N4C([H])([H])C([H])([H])OC([H])([H])C4([H])[H])C3=C([H])C([H])=C2[H])C([H])([H])[H])C([H])([H])[H])C([H])=C1[H])C([H])([H])[H]
[H]N(C(=O)C([H])([H])[H])C([H])([H])[C@]1([H])OC(=O)N(C2=C([H])C(F)=C(C([H])=C2[H])C2=C([H])C([H])([H])S(=O)(=O)C([H])([H])C2([H])[H])C1([H])[H]
[H]C([H])(SC([H])(C1([H])C([H])([H])C1([H])[H])C1([H])C([H])([H])C1([H])[H])C([H])([H])C(=O)N1[C@]([H])(C(=O)N2C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])[C@]2([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@]12[H]
[H]OC1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[C@]([H])(N([H])C(=O)[C@]([H])(N([H])C(=O)[C@@]1([H])N(C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])[H])[C@@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])[H])C([H])([H])C(=O)N([H])[H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])SSC([H])([H])[C@]([H])(N([H])C(=O)[C@@]1([H])N(C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])[H])[C@@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])[H])C([H])([H])C(=O)N([H])[H])C([H])([H])C([H])([H])C1([H])[H])C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C([H])([H])N([H])[C@]([H])(C(=O)N([H])[H])C([H])([H])C1=C([H])C([H])=C(O[H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])N=C(N([H])[H])N([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])N=C(N([H])[H])N([H])[H])C([H])([H])C1=C([H])C([H])=C(O[H])C([H])=C1[H])C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C([H])([H])N([H])[C@]([H])(C(=O)N([H])[H])C([H])([H])C1=C([H])C([H])=C(O[H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])N=C(N([H])[H])N([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])N=C(N([H])[H])N([H])[H]
[H]N(C(=O)[C@@]1([H])N(C(=O)[C@@]([H])(C([H])([H])C(=O)C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C1([H])[H])[C@@]([H])(C(=O)C(F)(F)C(F)(F)F)C([H])(C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])C(=C([H])C([H])=C1F)C([H])(O[C@@]1([H])C([H])([H])[C@]2([H])N(C([H])([H])[H])[C@@]([H])(C([H])([H])C2([H])[H])[C@@]1([H])C(=O)OC([H])([H])C([H])([H])C1=C([H])C(I)=C(N=[N+]=[N-])C([H])=C1[H])C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]N([H])C(=O)C1=NN(C2=C1C([H])([H])C([H])([H])C1=C([H])C([H])=C(N([H])C(=O)C3=C(Cl)N=C([H])C([H])=C3[H])C([H])=C21)C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]C([H])([H])C(=O)N1C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(C(=O)N([H])C1([H])C([H])([H])C([H])([H])N(C2=NC([H])=C([H])C([H])=C2C(F)(F)F)C([H])([H])C1([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C(F)(F)F
[H]C1=C([H])C(=C([H])C([H])=C1OC([H])([H])[H])C1=C([H])C(=O)C2=C([H])C(I)=C([H])C([H])=C2O1
[H]N(C(=O)OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C(=O)C1=NN(C(=C1C([H])([H])[H])C1=C([H])C([H])=C(Cl)C([H])=C1[H])C1=C([H])C([H])=C(Cl)C([H])=C1Cl
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[H]N([H])C1=C([H])C([H])=C(C([H])=C1N([H])C(=O)C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])S1
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[H]N(C(=O)N(C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NN(C([H])=C1C1=C2C([H])=C(N([H])C2=NC([H])=C1[H])C1=C([H])C([H])=C([H])C(=C1[H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C([H])([H])[H]
[H]N1C(=O)C2=C(C1=O)C1=C([H])N(C3=C1C([H])=C([H])C([H])=C3[H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C([H])([H])OC([H])([H])C([H])([H])N1C([H])=C2C2=C1C([H])=C([H])C([H])=C2[H]
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[H]N1C(=O)N(C(=O)C2=C([H])C(C3=C([H])N=C([H])O3)=C(OC([H])([H])[H])C([H])=C12)C([H])([H])[H]
[H]N1C([H])([H])C([H])([H])C([H])(OC2=C(SC3=C([H])C([H])=C(\C([H])=C(/[H])C(=O)N4C([H])([H])C([H])([H])OC([H])([H])C4([H])[H])C(=C3C(F)(F)F)C(F)(F)F)C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]OC1=C([H])C(F)=C(C([H])=C1[H])C1=NC2=C([H])C(O[H])=C([H])C(Br)=C2O1
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[H]N([H])C1=C2C(=C([H])S1)C(=NN(C2=O)C1=C([H])C([H])=C(C([H])=C1[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C(=O)OC([H])([H])C([H])([H])[H]
[H]OC(=O)C([H])([H])[C@@]([H])(N([H])C(=O)C([H])([H])C([H])([H])C(=O)N([H])C1=C([H])C([H])=C(C([H])=C1[H])C(=N[H])N([H])[H])C1=C([H])C([H])=C(F)C(F)=C1[H]
[H]N([H])N([H])C(=O)C1=C(SC2=C1C([H])([H])C([H])([H])N(C([H])([H])[H])C2([H])[H])N([H])[H]
[H]OC([H])([H])[C@@]1([H])O[C@@]([H])(N2C([H])=NC3=C2N=C(N=C3N([H])C([H])([H])[H])N2N=C([H])C(=C2[H])C2=C([H])C([H])=C([H])C([H])=N2)[C@]([H])(O[H])[C@]1([H])O[H]
[H]ON([H])C(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C(=O)C1=C([H])C([H])=C([H])N=C1[H]
[H]C1=C([H])C([H])=C2C(=C1[H])C(=O)C(=O)C([H])=C2S([O-])(=O)=O
[H]OC(=O)C1=C([H])C(=C([H])C2=C([H])C([H])=C([H])C([H])=C12)N1C([H])([H])C([H])([H])N(C(=O)C2=NC(C3=C([H])C([H])=C(C([H])=C3F)C([H])([H])[H])=C(C([H])=N2)C2=C([H])C([H])=C(OC([H])([H])[H])C([H])=C2[H])C([H])([H])C1([H])[H]
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[H]O[C@]1(C2=C([H])C(F)=C(F)C([H])=C2[H])C([H])([H])C([H])([H])N([H])C([H])([H])[C@]1([H])C(=O)N(C([H])([H])C1=C([H])N(C2=C1C(F)=C([H])C([H])=C2C([H])([H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C([H])([H])C([H])([H])C([H])([H])OC([H])([H])[H])C1([H])C([H])([H])C1([H])[H]
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[O-][N+](=O)C1=C(SC2=NNC(=S)S2)C=CC(=C1)S(=O)(=O)C(F)(F)F
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[H]N(C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)N(C([H])([H])[H])C([H])([H])[H])C1=C([H])C(OC([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])=NC2=C(C([H])=NN12)C([H])(C([H])([H])[H])C([H])([H])[H]
[H]ON(C([H])=O)C1(C([H])([H])S(=O)(=O)N2C([H])([H])C([H])([H])C([H])(C([H])([H])C([H])([H])C3=C([H])C([H])=C(C([H])=C3C([H])([H])[H])S(=O)(=O)C([H])([H])[H])C([H])([H])C2([H])[H])C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]O[C@](C1=C([H])C([H])=C(C([H])=C1[H])C(=O)N(C([H])([H])C(F)(F)F)C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])(C([H])([H])[H])C(F)(F)F
[H]OC(=O)C([H])([H])C([H])([H])[C@]([H])(N([H])C(=O)C1=C([H])C(=C([H])C(=N1)C1=C([H])C([H])=C([H])C([H])=C1[H])N1C([H])([H])C([H])([H])[C@@]([H])(C([H])([H])OC([H])([H])[H])C1([H])[H])C(=O)N1C([H])([H])C([H])([H])N(C(=O)OC([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N=C(N([H])[H])N([H])C([H])([H])C([H])([H])C([H])([H])[C@]1([H])N([H])C(=O)[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)C2=C([H])C(=C([H])C([H])=C2SC([H])([H])[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])C1=O)C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C(=O)N([H])[H])[N+]([O-])=O)C([H])([H])C1=C([H])N=C([H])N1[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C1=C([H])C(=C([H])C([H])=C1F)C([H])(O[C@@]1([H])C([H])([H])[C@@]2([H])N(C([H])([H])C([H])([H])C([H])([H])C([H])([H])C3=C([H])C([H])=C(N=[N+]=[N-])C(I)=C3[H])[C@]([H])(C([H])([H])C2([H])[H])C1([H])[H])C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]C1=C([H])C([H])=C(C(OC([H])([H])C([H])([H])C([H])([H])N2C([H])([H])C([H])([H])N(C3=C([H])C(=C([H])C([H])=C3[H])C(F)(F)F)C([H])([H])C2([H])[H])=C1[H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C(OC([H])([H])[H])=C1[H]
[H]OC(=O)C1=C([H])C([H])=C(C([H])=C1OC([H])(C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])N([H])C([H])([H])[C@]([H])(O[H])C1=C([H])C([H])=C([H])N=C1[H]
[H]C1=C(N(N=C1OC([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C(Cl)C(Cl)=C1[H])C([H])([H])[H]
[H]O[C@@]1([H])C([H])([H])N(C(=O)C([H])([H])SC2=C(C([H])=C([H])C(=C2[H])C2=NN(C3=C2C([H])([H])N(C([H])([H])C3([H])[H])S(=O)(=O)C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])N2C([H])([H])C([H])([H])C([H])(N3C(=O)C([H])([H])C([H])([H])C3([H])[H])C([H])([H])C2([H])[H])C(F)(F)F)C([H])([H])C1([H])[H]
[H]OC1([H])C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C3=C(OC4=C5C3=NN([H])C(=O)C5=C([H])C([H])=C4[H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]C1=C([H])C([H])=C2C(=C1[H])C(=O)C1(C2([H])[H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C2=C([H])C([H])=C([H])C3=C([H])C([H])=C([H])C([H])=C23)C([H])([H])C1([H])[H]
[H]O[C@]([H])(C#CC1=NC2=C(N=C([H])N2[C@]2([H])O[C@]([H])(C(=O)N([H])C([H])([H])C([H])([H])[H])[C@@]([H])(O[H])[C@@]2([H])O[H])C(=N1)N([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC1=C([H])C([H])=C([H])C([H])=C1C(=O)N([H])\N=C(/[H])C1=C([H])C([H])=C(OC(=O)C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])=C1[H]
[H]N1C([H])([H])C(=C([H])C([H])([H])C1([H])[H])C1=C([H])N(C2=C([H])C([H])=C([H])C([H])=C12)S(=O)(=O)C1=C(Cl)C([H])=C([H])C([H])=C1[H]
[H]N([H])C1=NN2C([H])=C([H])C([H])=NC2=C1C1=NC([H])=NC(N([H])C([H])(C([H])([H])[H])C([H])([H])[H])=C1[H]
[H]N=C(N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H])C1=C([H])C(F)=C(C([H])=C1[H])C(=O)N([H])[C@]([H])(C([H])([H])C([H])([H])[H])C(C(=O)N1C([H])([H])C([H])([H])C([H])(C([H])([H])C(=O)OC([H])([H])C([H])([H])[H])C([H])([H])C1([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]N([H])C1=NC2=C(OC3=C([H])C([H])=C(Cl)C([H])=C23)C(=N1)N1C([H])([H])[C@@]2([H])N([H])C([H])([H])C([H])([H])[C@@]2([H])C1([H])[H]
[H]OC1=C([H])C(=C([H])C([H])=C1[H])[C@]1(C([H])([H])[H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])C2=C([H])C([H])=C([H])O2)C([H])([H])[C@]1([H])C([H])([H])[H]
[H]N(C1=NC(=C([H])C([H])=N1)C1=C(N(C(=O)S1)C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)N([H])C([H])([H])C([H])([H])OC([H])([H])[H]
[H]N(C(=O)C1=C([H])N(C2=C([H])C([H])=C(Cl)C([H])=C2[H])C2=NC([H])=C([H])C([H])=C2C1=O)C1=C(Cl)C([H])=NC([H])=C1Cl
[H]OC([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C([H])([H])[C@]1([H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]C1=C(N=NN1C([H])([H])[C@]1([H])OC(=O)N(C2=C([H])C([H])=C(C(F)=C2[H])C2=C([H])C([H])([H])S(=O)(=O)C([H])([H])C2([H])[H])C1([H])[H])C(=O)OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]OC1=C([H])C([H])=C(C([H])=C1OC([H])([H])[H])C([H])([H])C(=O)N([H])C([H])([H])[C@@]([H])(C(\[H])=C(/[H])C(=O)OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)C([H])([H])[H])C1=C([H])C(=NC(=N1)N1N=C(C([H])=C1C([H])([H])[H])C([H])([H])[H])C1=C([H])C(=C([H])C([H])=C1[H])C([H])([H])[H]
[H]N(C(=O)C([H])([H])[H])C1=C([H])C([H])=C([H])C(=C1[H])C([H])([H])N1C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])C2=C([H])N([H])C3=C([H])C([H])=C(C([H])=C23)N2C([H])=NN=C2[H])C([H])([H])C1([H])[H]
CC1=C(OCCCCN2CCN(CC2)C2=CC=CC3=CC(F)=CC=C23)C=C2C(=O)NCC2=C1
[H]N(C(=O)C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(N1C([H])([H])[H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C(OC([H])([H])[H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]OC(=O)C(\[H])=N\O[C@]([H])(C1=C([H])C([H])=C(OC([H])([H])C2=NC3=C(S2)C([H])=C([H])C(F)=C3[H])C([H])=C1[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N1C([H])=C(C2=C1C([H])=C([H])C([H])=C2[H])C([H])([H])N1C(=O)C2(C([H])([H])C([H])([H])N(C3=NC4=C(C([H])=C([H])C([H])=C4[H])C3([H])[H])C([H])([H])C2([H])[H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(C(=O)C([H])([H])C1=C(N(C(=O)C2=C([H])C([H])=C(Cl)C([H])=C2[H])C2=C([H])C([H])=C(OC([H])([H])[H])C([H])=C12)C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C(=O)OC([H])([H])[H]
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[H]N(C([H])([H])[C@]1([H])C([H])([H])[C@@]1(C(=O)N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N([H])C1=NC(N([H])[H])=C(C([H])=N1)C([H])([H])C1=C([H])C([H])=C(OC([H])([H])C([H])([H])C([H])([H])OC([H])([H])C([H])([H])C([H])([H])OC2=C([H])C([H])=C([H])C([H])=C2[H])C(OC([H])([H])[H])=C1[H]
[H]N([H])C1=NN2C([H])=C([H])C([H])=NC2=C1C1=NC([H])=NC(=C1[H])N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(C1=NC(=C([H])S1)C1=C(N=C2N=C([H])C([H])=C([H])N12)C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N([H])C(=O)C1([H])C([H])([H])C([H])([H])N(C2=C([H])C([H])=C(N([H])C3=NC(N([H])C4=C(C([H])=C([H])C([H])=C4[H])S(=O)(=O)C([H])([H])C([H])([H])C([H])([H])[H])=C(Cl)C([H])=N3)C(OC([H])([H])[H])=C2[H])C([H])([H])C1([H])[H]
[H]N(C(=O)C([H])([H])N(C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C(OC2=C([H])C([H])=C([H])C([H])=C2[H])C([H])=C1[H]
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[H][C@@]12COC3=CC(=CC=C3N1C(=O)O[C@H]2CNC(C)=O)C1=CC=C(N=C1)C#N
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[H]N([H])C(=O)C1=NN(C2=C1C([H])([H])C([H])([H])N(C1=C([H])C([H])=C(C([H])=C1[H])N1C(=O)C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C2=O)C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
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[H]O[C@]([H])(C1=C([H])C([H])=C(S1)S(=O)(=O)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])[C@]1([H])N(C(=O)C([H])([H])[C@]1([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H]
[H]N1C([H])([H])[C@@]([H])(N2C3=C(C([H])=C([H])C([H])=C3[H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])[C@@]1([H])C(=O)N1C([H])([H])SC([H])([H])C1([H])[H]
[H]N([H])C1=C([H])C(C2=C([H])C([H])=C(C([H])=C2[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])=C(C([H])=C1[H])S(=O)(=O)N([H])C1=C(C(=NO1)C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)[C@@]([H])(N1C(=O)[C@@]([H])(N2C(=O)OC([H])([H])[C@]2([H])C2=C([H])C([H])=C([H])C([H])=C2[H])[C@@]1([H])C(\[H])=C(/[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
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[H]N(C(=O)C1=C(N([H])C2=NN([H])C([H])=C2[C@@]1([H])C1=C([H])C([H])=C([H])S1)C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C(F)(F)F
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[H]N(C(=O)C1=C([H])C([H])=C([H])C(=C1[H])C([H])([H])[H])C1=C([H])C([H])=C([H])C(N([H])C2=C([H])C([H])=C3C(=C2[H])C([H])([H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2C3=O)=C1[H]
[H]O[C@@](C(=O)N([H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C([H])C(=C2[H])C([H])([H])N([H])[H])C([H])([H])C1([H])[H])(C1=C([H])C([H])=C([H])C([H])=C1[H])[C@]1([H])C([H])([H])C([H])([H])C(F)(F)C1([H])[H]
[H]OC(=O)C1=C([H])C([H])=C([H])C(=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N([H])C1=NC(=NC2=C1N=C([H])N2C([H])(C([H])([H])[H])C([H])([H])[H])N([H])[C@@]1([H])C([H])([H])C([H])([H])[C@]([H])(N([H])[H])C([H])([H])C1([H])[H]
[H]\C(C1=C([H])C([H])=C(S1)C1=C([H])C([H])=C(SC([H])([H])[H])C([H])=C1[H])=C1\C([H])([H])N2[C@]3([H])C([H])([H])C([H])([H])[C@@]2([H])[C@]([H])(C(=O)OC([H])([H])[H])[C@@]1([H])C3([H])[H]
[H]S\C(=N/N=C(\[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1C([H])([H])C([H])([H])C([H])(C([H])([H])C([H])([H])OC([H])(C2=C([H])C([H])=C([H])C([H])=C2[H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H])S(=O)(=O)C([H])([H])[H]
[H]O[C@]1([H])C([H])([H])N(C2=NC3=C(C(N([H])[H])=C(S3)C(=O)N([H])[H])C(=C2[H])C([H])([H])[H])C([H])([H])C([H])([H])C1([H])[H]
[H]N([H])C1=C([H])C([H])=C([H])C([H])=C1N([H])C(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C(=O)C1=C([H])C(=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]\C(=N/N(C([H])([H])[H])S(=O)(=O)C1=C(C([H])=C([H])C(=C1[H])[N+]([O-])=O)C([H])([H])[H])C1=C2N(N=C1[H])C([H])=C([H])C([H])=C2C([H])([H])[H]
[H]N(C(=O)[C@@]1([H])N(C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C([H])([H])[H])C([H])([H])[H])C2([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C([H])([H])C1([H])[H])C1=C(N=NS1)C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C1=C([H])N(N=N1)C1=C([H])C([H])=C([H])C(=C1[H])C([H])([H])N1C(=O)C2(C([H])([H])C([H])([H])N(C3=NC4=C(N=C3[H])C([H])=C([H])C([H])=C4[H])C([H])([H])C2([H])[H])C([H])([H])C([H])([H])C1([H])[H]
[H]OC(=O)C1=C([H])C([H])=C(O1)C([H])([H])N(C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C(=O)N([H])C1=C([H])C([H])=C(OC2=C([H])C([H])=C([H])C([H])=C2[H])C([H])=C1[H]
[H]N([H])C1=NC(N([H])[H])=C2C(N=C([H])C(=C2C([H])([H])[H])C([H])([H])N([H])C2=C([H])C([H])=C(OC([H])([H])[H])C3=C2C([H])=C([H])C([H])=C3[H])=N1
[H]N(C(=O)OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])S(=O)(=O)C1=C([H])C([H])=C([H])C([H])=C1C1=C([H])C(F)=C(C([H])=C1[H])C([H])([H])N1C(=O)N(N=C1C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C1=C([H])C(=C([H])C([H])=C1Cl)C(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]N(C(=O)C(\[H])=C(/[H])C1=C2N(C(=O)C3(OC([H])([H])C([H])([H])O3)C2=C([H])C([H])=C1[H])C([H])([H])C1=C(Cl)C([H])=C(Cl)C([H])=C1[H])S(=O)(=O)C1=C([H])C(Cl)=C(Cl)S1
[H]N(C(=O)OC1=C([H])C([H])=C2O[C@]3([H])OC([H])([H])C([H])([H])[C@@]3(C2=C1[H])C([H])([H])[H])C1=C(C([H])=C([H])C([H])=C1[H])C([H])([H])[H]
[H]O\C(OC([H])([H])[H])=C1\C(=NC(=C(C(=O)OC([H])([H])[H])[C@@]1([H])C1=C([H])C(N([H])C(=O)N([H])C([H])([H])C([H])([H])C([H])([H])N2C([H])([H])C([H])([H])C([H])(C3=C([H])C([H])=C([H])C([H])=C3OC([H])([H])[H])C([H])([H])C2([H])[H])=C([H])C([H])=C1[H])C([H])([H])[H])C([H])([H])[H]
[H]N=C(N([H])[H])N1C([H])([H])C2=C(C([H])=C([H])C(O[C@@]([H])(C(=O)OC([H])([H])C([H])([H])[H])C3=C([H])C([H])=C(OC4([H])C([H])([H])C([H])([H])N(C(=N[H])C([H])([H])[H])C([H])([H])C4([H])[H])C([H])=C3[H])=C2[H])C([H])([H])C1([H])[H]
[H]N(C1=C2N=C(N(C2=NC(=N1)C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)C([H])([H])[H])C([H])([H])[H])C([H])(C1([H])C([H])([H])C1([H])[H])C1([H])C([H])([H])C1([H])[H]
CC1=CC(OCCCC2=C(OC3=CC=CC=C23)C(O)=O)=CC(C)=C1Cl
[H]N(C([H])([H])C([H])([H])C1=C(N([H])C2=C1C([H])=C([H])C([H])=C2[H])C1=C([H])C(=C([H])C(=C1[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])[N+]([O-])=O
[H]N1C(=O)N([H])C(=O)C(N2C([H])([H])C([H])([H])C([H])(C([H])([H])O[N+]([O-])=O)C([H])([H])C2([H])[H])(C1=O)C1=C([H])C([H])=C(OC2=C([H])C([H])=C([H])C([H])=C2[H])C([H])=C1[H]
[H]OC(=O)C1=C([H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])O\C([H])=C(/C2=C(F)C([H])=C([H])C([H])=C2[H])C2=C(C([H])=C([H])C([H])=C2[H])C([H])([H])[H])C1([H])[H]
CC(C)(C)OC(=O)N1CCN(CC1)S(=O)(=O)C1=CC=C(NC(=O)C=C)C=C1
COC1=CC=C2CC3N(CCC4=CC5=C(OCO5)C=C34)CC2=C1OC(=O)C1=CC=CC=C1OC(C)=O
[H]OC1=NC2=C([H])C([H])=C([H])C([H])=C2N=C1C1=C2C(=C([H])C([H])=C1[H])C(=O)N(C2([H])[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]OC(=O)C1=C([H])C(=C([H])C([H])=C1C1=C(C([H])=C(C#CC([H])([H])O[H])C([H])=C1[H])C(=O)N([H])C1=C([H])C([H])=C(C([H])=C1[H])C(=N[H])N([H])[H])C(=O)N([H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]O[C@@]1([H])C([H])([H])[C@@]2(C([H])([H])[H])[C@@]([H])(C([H])([H])[C@@]([H])(C([H])([H])[H])[C@]2(O[H])C(=O)C([H])([H])SC([H])([H])C([H])([H])N([H])C(=S)N([H])C([H])([H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=O)C([H])([H])C([H])([H])N([H])C(=O)C([H])([H])[H])[C@]2([H])C([H])([H])C([H])([H])C3=C([H])C(=O)C([H])=C([H])[C@]3(C([H])([H])[H])[C@@]12F
[H]C1=NC(OC2([H])C([H])([H])N(C3=C([H])C([H])=C4C([H])=C([H])C([H])=C([H])C4=N3)C2([H])[H])=C(N=C1[H])C1([H])C([H])([H])C([H])([H])N(C(=O)OC([H])([H])[H])C([H])([H])C1([H])[H]
[H]O[C@@]1([H])[C@]([H])(N([H])S(=O)(=O)C2=C([H])C([H])=C(C([H])=C2[H])C([H])([H])C([H])([H])[H])C2=C([H])C(=C([H])C([H])=C2OC1(C([H])([H])[H])C([H])([H])[H])C(=O)N(C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H]
[H]N(C(=O)C(=O)C1=C2C([H])=C([H])C([H])=C([H])C2=C(N([H])C2=C([H])C([H])=NC([H])=C2[H])C([H])=C1[H])C1=C(OC([H])([H])[H])C(N([H])S(=O)(=O)C([H])([H])[H])=C([H])C(=C1[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]OC1=C([H])C(=NC(=C1[H])C1=C([H])N([H])C2=NC([H])=C([H])C([H])=C12)N([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N([H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])N([H])C([H])([H])C([H])([H])N([H])S(=O)(=O)C1=C([H])C([H])=C2C([H])=C([H])C([H])=C([H])C2=C1Cl
[H]N(C(=O)OC1=C([H])C([H])=C2C(=C1[H])[C@]1([H])C([H])([H])[C@@]2([H])N(C([H])([H])C([H])([H])[H])C([H])([H])C1([H])[H])C([H])([H])[H]
CN1N=C(CC(=O)NC2=C(Cl)C=C(Cl)C=C2)C2=CC=CC=C2C1=O
[H]OC([H])([H])[C@@]1([H])O[C@@]([H])(N2C([H])=NC3=C2N=C([H])N=C3N([H])C([H])([H])[C@]([H])(C2=C([H])C(OC([H])([H])[H])=C([H])C(OC([H])([H])[H])=C2[H])C2=C(C([H])=C([H])C([H])=C2[H])C([H])([H])[H])[C@]([H])(O[H])[C@]1([H])O[H]
[H]OC(=O)C([H])([H])N([H])[C@@]([H])(C(=O)N1C([H])([H])C(F)(F)C([H])([H])[C@@]1([H])C(=O)N([H])C([H])([H])C1=C([H])N=C(C([H])=C1[H])C(=N[H])N([H])[H])C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]OC1=C([H])C(\C([H])=C(\[H])C2=C([H])C3=C([H])C([H])=C([H])C([H])=C3C([H])=C2[H])=C([H])C([H])=C1OC([H])([H])[H]
[H]N(C(=O)N1C([H])([H])C([H])([H])N(C2=NC([H])=NC3=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C([H])=C23)C([H])([H])C1([H])[H])C1=C([H])C([H])=C(OC2=C([H])C([H])=C([H])C([H])=C2OC([H])([H])[H])C([H])=C1[H]
[H]N1C(=O)C2=C3C4=C(C([H])=C([H])C([H])=C4[H])N4C3=C3N(C5=C(C([H])=C([H])C([H])=C5[H])C3=C2C1([H])[H])[C@@]1(O[C@@]4([H])C([H])([H])[C@]([H])(N(C([H])([H])[H])C([H])([H])C([H])([H])[H])[C@]1([H])OC([H])([H])[H])C([H])([H])[H]
[H]OC1=C(Cl)C([H])=C2C(=C1[H])[C@@]1([H])C3=C(C(Br)=C([H])C([H])=C3[H])C([H])([H])C([H])([H])[C@]1([H])N(C([H])([H])[H])C([H])([H])C2([H])[H]
[H]OC1=C2C(=C([H])C([H])=C1C([H])([H])[H])[C@@]([H])(O[C@@]([H])(C2([H])[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])N([H])[H]
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[H]C1=C(N=C(S1)C([H])([H])[H])C#CC1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
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[H]N([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N1C(SC([H])([H])C([H])([H])C2=C([H])N([H])C3=C2C([H])=C([H])C([H])=C3[H])=NN=C1C1=NC2=C([H])C([H])=C(F)C([H])=C2C([H])=C1[H]
[H]N(C(=O)C([H])([H])C([H])([H])C1=C([H])C([H])=NC([H])=C1[H])C1=C([H])C([H])=C2N(C3=C(C([H])=C([H])C([H])=C3[H])C2=C1[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N1C([H])([H])C([H])([H])C([H])([H])[C@]([H])(C([H])([H])C([H])([H])OC2=C3N=C(N(C3=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C([H])([H])[C@]2([H])C([H])([H])N([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])OC2=C([H])C([H])=C(Cl)C([H])=C2[H])C1([H])[H]
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[H]N(C(=O)N([H])C1=C([H])C([H])=C(F)C([H])=C1F)C1=NC2=C(S1)C([H])([H])[C@]1(C([H])([H])[H])C([H])([H])C([H])([H])[C@]3([H])[C@@]([H])(OC(=O)[C@@]3([H])C([H])([H])[H])[C@@]1([H])[C@]2([H])C([H])([H])[H]
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[H]O[P@@](=O)(OC1=C(Cl)C([H])=C([H])C([H])=C1[H])OC([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=O)[C@]([H])(N([H])C(=O)[C@]1([H])N(C(=O)OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H]
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[H]N(C(=O)C1(N([H])C(=O)C(F)(F)F)C([H])([H])C1([H])[H])C([H])([H])C1=C(F)C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C([H])C(F)=C1C(=O)OC([H])([H])[H]
[H]OC1=C2N=C(N([H])[H])C([H])=C([H])C2=C([H])C([H])=C1[H]
[H]N1C(=NC2=C1N(C(=O)N(C2=O)C([H])([H])[H])C([H])([H])[H])C1=C(OC([H])([H])[H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]N([H])C1=NC([H])=C(C([H])=N1)C1=NC2=C(C([H])=C(S2)C([H])([H])C2([H])C([H])([H])C([H])([H])N(C([H])([H])C(F)(F)F)C([H])([H])C2([H])[H])C(=N1)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
C[N+]1=C(CCC2=CC=CC=C2)C=CC=C1CCC1=CC=CC=C1
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[H]N1C([H])([H])C([H])=C2C3=C(C([H])=C([H])C([H])=C3[H])C(=C2C1([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C1=NC([H])=C(C([H])=C1C1=C([H])C2=C3N(C(=O)C([H])([H])C2([H])[H])C([H])([H])C([H])([H])C3=C1[H])C(F)(F)F
[H]N([H])C1=NC(N([H])[H])=C(C#C[C@@]([H])(C2=C([H])C(OC([H])([H])[H])=C([H])C(=C2[H])C2=C([H])C(=C([H])C(=C2[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C(=N1)C([H])([H])[H]
[H]N([H])C1=NON=C1C1=NC2=C([H])N=C(N([H])C(=O)C3=C([H])C([H])=C(OC([H])([H])C([H])([H])N4C([H])([H])C([H])([H])OC([H])([H])C4([H])[H])C([H])=C3[H])C([H])=C2N1C([H])([H])C([H])([H])[H]
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[H]C1=C([H])C([H])=C2C(=C1[H])C(=O)N(N=C2C([H])([H])C1=C([H])C([H])=C2OC([H])([H])OC2=C1[H])C([H])([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])OC1=C([H])C2=C(C([H])=C1[H])C(=C([H])C(=O)O2)C([H])([H])[H]
[H]C1=NC([H])=C(C([H])=C1[H])C1=NN=C(SC([H])([H])C(=O)C2=C([H])C([H])=C(Cl)C([H])=C2[H])N1C([H])([H])C([H])([H])[H]
[H]N([H])C1=NC([H])=NC2=C1C(=C(Br)N2C1([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C(OC2=C([H])C([H])=C([H])C([H])=C2[H])C([H])=C1[H]
[H]O[C@]1(C2=C(C([H])=C([H])C(OC([H])([H])[H])=C2[H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])N([H])C([H])([H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])N([H])S(=O)(=O)C2=C([H])C([H])=C([H])C(Cl)=C2C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N(C1=NC2=C(SC(=C2[H])C2=C([H])C([H])=C([H])C([H])=C2[H])N2C1=NC([H])=C2C([H])([H])[H])C([H])([H])[H]
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[H]OC1=C2O[C@@]3([H])[C@]([H])(N([H])C(=O)C4=C([H])N=C([H])C([H])=C4[H])C([H])([H])C([H])([H])[C@@]4(O[H])[C@]5([H])N(C([H])([H])C6([H])C([H])([H])C6([H])[H])C([H])([H])C([H])([H])[C@]34C2=C(C([H])=C1[H])C5([H])[H]
[H]N(C1=C2C([H])=C(C([H])=C([H])C2=NC([H])=N1)C1=C(ON=C1C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C(=C([H])S1)C([H])([H])[H]
[H]OC1=C([H])C(=C(C(=C1[H])C([H])([H])[H])C([H])([H])[C@]([H])([N+]([H])([H])[H])[C@@]([H])(O[H])C([H])([H])C(\[H])=C(/[H])[C@@]([H])(O[H])[C@]([H])(C(=O)N([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H]
[H]ON([H])C1=NC(=O)N(C([H])=C1[H])[C@]1([H])O[C@]([H])(C([H])([H])OP([O-])([O-])=O)[C@@]([H])(O[H])C1([H])[H]
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[H]C1=C(N(N=C1C([H])([H])[H])C1=C([H])C([H])=C(Cl)C([H])=C1[H])C1([H])C([H])([H])C([H])([H])N(C(=O)[C@]2([H])C([H])([H])N(C([H])([H])[C@@]2([H])C2=C([H])C([H])=C(F)C([H])=C2F)C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N(C(=O)C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C(SC([H])=C1C([H])([H])[H])C(=O)OC([H])([H])[H]
[H]N(C(=O)C1=C([H])N=C(OC([H])([H])C(F)(F)F)C([H])=C1[H])[C@]1([H])C([H])([H])OC2=C([H])C([H])=C([H])C(C3=C([H])C(F)=C(OC([H])([H])[H])N=C3[H])=C2C1([H])[H]
CN(CCCCCN)CCCCCNC(=O)C1=NN(C(=C1C)C1=CC=C(Cl)C=C1)C1=C(Cl)C=C(Cl)C=C1
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[H]N(C(=O)N1C([H])([H])C([H])([H])N(C2=NC([H])=C([H])C([H])=C2Cl)C([H])([H])C1([H])[H])C1=C([H])C([H])=C(Br)C([H])=C1[H]
[H]O[C@@]([H])(C1=C([H])C([H])=C(OC([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])=C1[H])C([H])([H])N([H])C(=O)C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)OC([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])[H]
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[H]OC(=O)C#CC1=C(OC([H])([H])C([H])([H])C2=C([H])C([H])=C3C([H])=C([H])C([H])=C([H])C3=C2[H])C([H])=C(C([H])=C1[H])C([H])([H])N1N=C([H])C([H])=C1[H]
[H]N([H])C1=C(C2=NC3=C(N2[H])C([H])=C([H])C(=C3[H])N2C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C2([H])[H])C(=O)N([H])C2=C([H])C(N([H])C([H])([H])[H])=C([H])C([H])=C12
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[H]N1C(=O)C2(N(C3=C([H])C([H])=C([H])C([H])=C3[H])C1([H])[H])C([H])([H])C([H])([H])N(C([H])([H])C2([H])[H])[C@@]([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])[H]
[H]OC1=C2C([H])=C(C3=C([H])N=C([H])O3)C(OC([H])([H])[H])=C([H])C2=NC(=C1[H])C1=C([H])C([H])=C2OC([H])([H])C([H])([H])[C@]([H])(N(C([H])([H])[H])C([H])([H])[H])C2=C1[H]
[H]N(C(=O)[C@]1([H])N(C(=O)OC([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])OC1([H])[H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C2(C3=C([H])C([H])=C([H])C([H])=C3C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]N(C([H])([H])C([H])([H])OC1=C(OC([H])([H])[H])C([H])=C([H])C([H])=C1OC([H])([H])[H])C([H])([H])[C@]1([H])OC2=C(Cl)C([H])=C([H])C([H])=C2OC1([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])N(C([H])([H])[H])[C@@]1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])N1C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(C1=NC([H])=NC2=C1C(=C(N2[H])C([H])([H])[H])C([H])([H])[H])C1=C([H])C(=C([H])C([H])=C1[H])C(F)(F)F
[H]N1C([H])([H])C([H])([H])N(C2=C([H])C(OC([H])([H])[H])=C(Br)N=C2[H])C([H])([H])C1([H])[H]
[H]OC1=C(C(Cl)=C([H])C([H])=C1N([H])C1=C(N([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C(=O)C1=O)S(=O)(=O)N1C([H])([H])C([H])([H])C([H])(N2C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]OC1=C([H])C(OC([H])([H])C([H])([H])C([H])([H])C([H])([H])OC2=C([H])C(O[H])=C([H])C(=C2[H])[N+](C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])=C([H])C(=C1[H])[N+](C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]O[C@]([H])(C([H])([H])OC1=C(C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])=C([H])[H])C([H])([H])N1C([H])([H])C([H])([H])C([H])(N2C(=O)C3=C([H])C([H])=C([H])C4=C([H])C([H])=C([H])C(C2=O)=C34)C([H])([H])C1([H])[H]
[H]OC(=O)[C@@]([H])(N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])N([H])S(=O)(=O)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H]
[H]C1=C([H])C([H])=C(OC([H])([H])[C@@]2([H])N(C([H])([H])C2([H])[H])S(=O)(=O)C2=C([H])C([H])=C3N(C(=O)C(=O)C3=C2[H])C([H])([H])[H])C([H])=C1[H]
[H]N(C1=C([H])C(OC([H])([H])[H])=C(Cl)C([H])=C1Cl)C1=C(C#N)C([H])=NC2=C([H])C(OC([H])([H])C([H])([H])C([H])([H])N3N=NC([H])=C3[H])=C(OC([H])([H])[H])C([H])=C12
[H]OC(=O)C([H])([H])C([H])([H])C([H])([H])C(\[H])=C(\C1=C([H])N=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])N([H])S(=O)(=O)C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]OC1=C(OC([H])([H])[H])C([H])=C(C([H])=C1I)C([H])([H])N([H])C(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C(\[H])=C(/[H])C([H])([H])[C@]([H])(OC(=O)C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]N(C(=O)N([H])[C@]12C([H])([H])[C@@]3([H])C([H])([H])[C@]([H])(C([H])([H])[C@]([H])(C3([H])[H])C1([H])[H])C2([H])[H])C1=C([H])C([H])=C(OC([H])([H])C([H])([H])C([H])([H])N2C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C2([H])[H])C([H])=C1[H]
[H]N(C(=O)N([H])C([H])([H])C([H])([H])C(=O)OC([H])([H])C([H])([H])[H])C1=C([H])C2=C(N=C(C3=C([H])C([H])=C([H])O3)C(=N2)C2=C([H])C([H])=C([H])O2)C([H])=C1[H]
[H]N(\N=N\C1=C([H])C([H])=C2N=C([H])N=C(N([H])C3=C([H])C(Cl)=C([H])C([H])=C3[H])C2=C1[H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C([H])([H])N([H])S(=O)(=O)C1=C([H])C([H])=C([H])C2=C(C([H])=C([H])C([H])=C12)N(C([H])([H])[H])C([H])([H])[H]
[H]OC([H])([H])C([H])([H])N([H])C1=NC2=C([H])C([H])=C([H])C([H])=C2N2C1=NN=C2C([H])([H])C([H])([H])[H]
[H]OC([H])([H])[C@]([H])(N(C([H])([H])C([H])([H])N(C(=O)N([H])C1=C([H])C(Cl)=C(F)C([H])=C1[H])[C@]1([H])C([H])([H])C([H])([H])[C@]2(C3=C([H])C([H])=C([H])C(C#N)=C3[H])C([H])([H])[C@]2([H])C1([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H]
[H]OC1=C([H])C(=C([H])C([H])=C1[H])[C@]1(C([H])([H])[H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2=C([H])C([H])=C([H])S2)C([H])([H])[C@]1([H])C([H])([H])[H]
[H]O[C@@]([H])(N1C([H])([H])C([H])([H])C([H])([H])[C@@]([H])(C([H])([H])C2=C([H])C([H])=C(F)C([H])=C2[H])C1([H])[H])C([H])([H])[C@]([H])(N([H])C(=O)N([H])C1=C([H])C(=C([H])C(Br)=C1[H])C1=NN=NN1C([H])([H])[H])C([H])([H])[H]
[H]OC(=O)[C@@]([H])(N([H])C(=O)C1=C([H])C([H])=C([H])C([H])=C1N([H])C(=O)C1=C([H])C2=C([H])C([H])=C([H])C([H])=C2S1)C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N([H])C1=C(C(=O)C([H])([H])[H])C(=NN(C1=O)C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C([H])C([H])=C([H])C([H])=C2OC([H])([H])[H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C1=C(OC(F)(F)F)C([H])=C(Br)C(=C1[H])N(C1=NC(=NC(=N1)C([H])([H])[H])N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H]
[H]N1N=C([H])C2=C1C(=C([H])C(=C2[H])C([H])([H])[C@]([H])(OC(=O)N1C([H])([H])C([H])([H])C([H])(N2C(=O)N([H])C3=C(C([H])=C([H])C([H])=C3[H])C2([H])[H])C([H])([H])C1([H])[H])C1=C([H])C(C#N)=C([H])C([H])=N1)C([H])([H])[H]
OC12CC3CC(C1)CC(C3)(C2)C(=O)N1CCC2=C1C=CC=C2
[H]N1C([H])([H])C([H])([H])[C@@]2(OC([H])([H])C3=C2C([H])=C(F)C(F)=C3[H])[C@@]([H])(C(=O)N(C([H])([H])C2=C([H])C(=C([H])C(OC([H])([H])C([H])([H])OC([H])([H])[H])=C2[H])C([H])([H])C([H])([H])C([H])([H])OC([H])([H])[H])C2([H])C([H])([H])C2([H])[H])C1([H])[H]
[H]C1=C([H])C(=C([H])C([H])=C1Br)C([H])([H])C(=O)N1C([H])([H])C([H])([H])[N@]2C([H])([H])C([H])([H])[C@]1([H])C([H])([H])C2([H])[H]
[H]N([H])C([H])([H])C1=C([H])C(=C([H])C([H])=C1[H])N1N=C(C([H])=C1C(=O)N([H])C1([H])C([H])([H])C([H])([H])N(C2=C([H])C([H])=C([H])C([H])=C2S(=O)(=O)C([H])([H])[H])C([H])([H])C1([H])[H])C(F)(F)F
[H]N1C(=S)S\C(=C(\[H])C2=C([H])C3=C(OC([H])([H])C(=O)N3C([H])([H])C([H])([H])C3=C([H])C([H])=C(OC([H])([H])[H])C([H])=C3[H])C([H])=C2[H])C1=O
[H]C1=C(Cl)C([H])=C(C#CC([H])([H])OC2=NSN=C2[C@]23C([H])([H])[C@]4([H])C([H])([H])[C@@]2([H])[C@@]3([H])C4([H])[H])C([H])=C1Cl
[H]N(C1=NC([H])=C(S1)C#N)C1=C([H])C(=C([H])C([H])=N1)C([H])([H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]C1=C([H])C(OC(=O)C([H])([H])[H])=C(SC([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])Br)C([H])=C1[H]
[H]N(C([H])([H])C(=O)N1C([H])([H])C([H])([H])C([H])([H])[C@]1([H])C#N)C([H])([H])C([H])([H])N1C(=O)N(C2=C([H])C(OC([H])([H])[H])=C([H])C(OC([H])([H])[H])=C2[H])C([H])([H])C1([H])[H]
[H]N(C(=O)C1=C(N2C([H])=NN=C2C([H])=C1C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H])C([H])([H])C1=C([H])C(=C([H])C(=C1[H])C(F)(F)F)C(F)(F)F
[H]C1=C([H])C([H])=C(S1)C1=C([H])C([H])=C(C([H])=C1[H])C1=NC2=C([H])C([H])=C(F)C([H])=C2C(C([O-])=O)=C1C([H])([H])[H]
[H]C1=NC(OC2([H])C([H])([H])N(C3=C([H])C([H])=C4C([H])=C([H])C([H])=C([H])C4=N3)C2([H])[H])=C(N=C1[H])N1C([H])([H])[C@@]2([H])C([H])([H])C([H])([H])[C@]1([H])C2([H])[H]
[H]N(C(=O)C([H])([H])C([H])([H])C(=O)O[C@]1([H])C2=C(C([H])=C3OC([H])([H])OC3=C2[H])[C@]([H])(C2=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C(OC([H])([H])[H])=C2[H])[C@]2([H])C(=O)OC([H])([H])[C@@]12[H])C([H])([H])[C@@]([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H]
[H]ON([H])C(=O)C1=C([H])C2=C([H])C([H])=C(OC([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])=C2C([H])=C1[H]
[H]N(C(=O)C1=C(SC([H])([H])C([H])([H])C([H])([H])[H])N(N=C1[H])C([H])([H])[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
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[H]C1=C([H])C2=C(OC3([H])C([H])([H])C([H])([H])N(C([H])([H])C4=NC([H])=C([H])C([H])=C4C([H])([H])[H])C([H])([H])C3([H])[H])N=C([H])N=C2N1C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC([H])([H])C1=C([H])C([H])=C(C(=C1[H])N(C1=NC(=NC([H])=C1[H])N([H])C1=C([H])C(=C([H])C(=C1[H])C([H])([H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C([H])([H])[H])C([H])([H])[H]
[H]OC1=C([H])C2=C(C([H])=C1[H])C([H])([H])[C@@]([H])(N(C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[H])[C@]2([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C1=C([H])C([H])=C(C([H])=N1)C1=C([H])N=NC2=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C([H])=C12)C([H])(C([H])([H])[H])C([H])([H])[H]
[H]OC(=O)[C@]([H])(C1=C([H])C([H])=C(O[C@]2([H])C([H])([H])N(C(=N[H])C([H])([H])[H])C([H])([H])C2([H])[H])C([H])=C1[H])C([H])([H])C1=C([H])C2=C(O1)C([H])=C(C([H])=C2[H])C(=N[H])N([H])[H]
[H]N(C(=O)N1C2=C([H])C([H])=C(C(I)=C2C([H])([H])C1([H])[H])C([H])([H])[H])C1=C([H])C([H])=C([H])N=C1[H]
[H]N([H])C1=C([H])N=C(N(C1=O)C([H])([H])C(=O)N([H])[C@@]([H])(C(=O)C1=NC2=C(O1)C([H])=C([H])C(=C2[H])C(=O)OC([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=NC([H])=C1[H]
[H]N(C1=C([H])C2=C(C([H])=C([H])N2C([H])([H])C([H])([H])N2C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])=C1[H])S(=O)(=O)C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C2=C([H])C([H])=C([H])C([H])=C12
[H]N(C(=O)C([H])([H])C([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])C(Cl)=C([H])C(Cl)=C1[H]
[H]N=C(N([H])[H])C1=C([H])C(OC([H])([H])C(=O)N([H])C2=C([H])C([H])=C(C([H])=C2[H])C(=O)N2C([H])([H])C([H])([H])C([H])([H])[C@]2([H])C(=O)OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])=C([H])C([H])=C1[H]
[H]N(C(=O)C(=O)OC([H])([H])C([H])([H])[H])C1=NC([H])=C([H])C(=N1)C(\[H])=C(/[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)N([H])[C@@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])[C@@]([H])(C([H])([H])C2=C([H])C([H])=C(F)C([H])=C2[H])C1([H])[H])C1=C([H])C(=C([H])C(=C1[H])C(=O)C([H])([H])[H])C(=O)C([H])([H])[H]
[H]N(C(=O)N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C([H])([H])N([H])[C@]1([H])C2([H])C([H])([H])C([H])([H])[C@@]1([H])C([H])([H])N(C(=O)OC([H])([H])C([H])([H])[H])C2([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])[C@@]2(O[C@@]([H])(OC([H])([H])[H])C([H])([H])C3=C2C([H])=C([H])C([H])=C3[H])C1([H])[H]
[O-][N+]#[C-]
[H]N([H])C1=NC(=NC2=NC(=NN12)C1=C([H])C([H])=C([H])O1)N([H])C([H])([H])[C@]1([H])N(C([H])([H])C2=C(F)C(F)=C([H])C([H])=C2F)C([H])([H])C([H])([H])C1([H])[H]
[H]N(C(=O)C1=C([H])C(F)=C([H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C(=C1[H])C1=C([H])C(=C([H])C([H])=C1[H])C([H])([H])N1C([H])([H])C([H])([H])N([H])C([H])([H])C1([H])[H]
[H]N1C(=O)N(C(=O)C2=C1C([H])=C(C(=C2[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])N1C([H])([H])[C@@]2([H])C3=C([H])C([H])=C([H])C(OC([H])([H])[H])=C3C([H])([H])C([H])([H])[C@@]2([H])C1([H])[H]
[H]N(C(=O)C([H])([H])[H])C1=C([H])C(OC([H])([H])C(=O)N([H])[C@]([H])(C2=C([H])C3=C([H])C([H])=C([H])C([H])=C3C([H])=C2[H])C([H])([H])[H])=C([H])C([H])=C1[H]
[H]OC([H])([H])C(=O)N1C([H])([H])C([H])([H])C([H])(C(=O)N2C([H])([H])C([H])([H])[C@@]([H])(N(C(=O)C3=C([H])C([H])=C(C([H])=C3[H])C(F)(F)F)C([H])([H])[H])[C@]([H])(C3=C([H])C([H])=C(Cl)C(Cl)=C3[H])C2([H])[H])C([H])([H])C1([H])[H]
[H]N([H])C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)N1C2=C(C3=C1C([H])([H])C([H])([H])C([H])([H])C3([H])[H])C(N([H])C([H])([H])[H])=C([H])C([H])=C2[H]
[H]N(C(=O)C(F)(F)F)C1=C([H])C([H])=C2C(=O)N(C3=C(C([H])=C([H])C([H])=C3[H])C2=C1[H])C([H])([H])C([H])([H])[H]
[H]N(C1=C([H])C(OC([H])([H])[H])=C(Cl)C([H])=C1Cl)C1=C2C([H])=C(OC([H])([H])[H])C(C#CC3=NC([H])=C(C([H])=C3[H])C([H])([H])N3C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C3([H])[H])=C([H])C2=NC([H])=C1C#N
[H]O[C@@]1(C(=C([H])[C@@]([H])(OC(=O)C([H])([H])[H])[C@@]2(C([H])([H])[H])[C@@]1([H])C([H])([H])C([H])([H])[C@@]1(C([H])([H])[H])[C@@]3([H])C([H])=C([H])C([H])([H])OC([H])([H])[C@]3([C@]([H])(OC(=O)C([H])([H])[H])C([H])([H])[H])[C@@]([H])(OC(=O)C([H])([H])[H])[C@@]([H])(OC(=O)C([H])([H])[H])[C@]21[H])C([H])([H])[H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1F
[H]C1=C([H])\C(=N/C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C2=C(C([H])=C(Cl)C([H])=C2[H])N1C([H])([H])C1=C([H])C([H])=C(Cl)C(Cl)=C1[H]
[H]N(C(=O)C1=NSC2=C([H])C([H])=C([H])C([H])=C12)C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C(OC([H])([H])[H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]OC1=C(O[H])/C(=N\C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])/C\1=N/C1=C([H])C([H])=C([H])C(C(=O)N(C([H])([H])[H])C([H])([H])[H])=C1O[H]
[H]N1C2=C([H])C(C#CC3=C([H])C([H])=C(F)C([H])=C3[H])=C([H])C([H])=C2N=C(C2=C([H])C([H])=C([H])C(=C2[H])N2N=C([H])N=C2[H])C([H])([H])C1=O
[H]N=C(N([H])[H])N([H])C1=NC([H])=C(Cl)C([H])=C1\C([H])=C(/[H])C(=O)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]C1=C([H])C(=C([H])C(=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])[C@]([H])(C([H])([H])[H])[C@@]([H])(C(=O)N1C([H])([H])C([H])([H])[C@]([H])(F)C1([H])[H])[N+]([H])([H])[H])S(=O)(=O)C([H])([H])[H]
[H]N1C2=C(C3=C1C([H])([H])C([H])([H])N([H])C3=O)C([H])([H])C([H])([H])C([H])([H])C1=C2C([H])=C(N=C1[H])C1=C([H])N=C([H])C(OC([H])([H])C([H])([H])OC([H])([H])[H])=C1[H]
[H]N([H])S(=O)(=O)C1=NN=C(S1)N([H])C(=O)OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C1=NOC2=C1C([H])=C(C([H])=C2[H])C(F)(F)F)C([H])([H])C(=O)N([H])C1([H])C([H])([H])N(C1([H])[H])[C@@]1([H])C([H])([H])C([H])([H])[C@@]([H])(C2=C([H])C3=C(OC([H])([H])O3)C([H])=C2[H])C([H])([H])C1([H])[H]
[H]C(=O)C1=C(N(C(=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)C([H])([H])[H])C1=C([H])C([H])=C(F)C([H])=C1[H])C([H])([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C([H])C([H])=C1[H])[C@]1([H])C(=O)N(C([H])([H])C1([H])[H])[C@@]1([H])C([H])([H])C([H])([H])[C@@]([H])(N(C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])[C@@]1([H])C([H])([H])S(=O)(=O)C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC1=C([H])C([H])=C(Cl)C(=C1[H])C1=C([H])C(=C2N=C(N=NC2=C1[H])N([H])C1=C([H])C(OC([H])([H])C([H])([H])N2C([H])([H])C([H])([H])C([H])([H])C2([H])[H])=NC(=N1)C([H])([H])[H])C([H])([H])[H]
[H]N1C(=C([H])C2=C1C([H])=C([H])C(Cl)=C2[H])C(=O)N1C([H])([H])C([H])([H])N([H])C([H])([H])C([H])([H])C1([H])[H]
[H]OC(=O)C1=C([H])C(=C([H])C(=C1[H])N1C([H])([H])C([H])([H])C([H])([H])S1(=O)=O)N1C(=C([H])C([H])=C1C([H])([H])[H])C1=C([H])C(Cl)=C([H])C([H])=C1OC([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC1=C2C([H])=C([H])C([H])=C([H])C2=NN1[H]
[H]C1=[N+]([H])C(F)=C([H])C2=C1N=C1N2C([H])([H])[C@]([H])([N+]([H])([H])[H])[C@@]([H])(C2=C(F)C([H])=C(F)C(F)=C2[H])C1([H])[H]
[H]C1=C([H])C(=C([H])C(OC([H])([H])[H])=C1OC([H])([H])[H])C1=NN(C(=O)[C@]2([H])C([H])([H])C([H])([H])[C@]12[H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]C1=NC(=C([H])S1)C([H])([H])N1C([H])([H])C([H])([H])C(=C(C2=C([H])C([H])=C(C([H])=C2[H])C(=O)N2C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])C2=C3N=C([H])C([H])=C([H])C3=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N([H])[C@@]([H])(C([H])([H])C(=O)N1C([H])([H])C2=NC(=NN2C([H])([H])C1([H])[H])C1([H])C([H])([H])C1([H])[H])C([H])([H])C1=C(F)C([H])=C(F)C(F)=C1[H]
[H]O[C@@]1([H])C([H])([H])N(C(=O)C([H])([H])[H])[C@]([H])(C(=O)N([H])[C@@]([H])(C(=O)C2=NC([H])=C([H])S2)C([H])([H])C([H])([H])C([H])([H])N=C(N([H])[H])N([H])[H])C1([H])[H]
[H]N1C([H])([H])C([H])([H])[C@@]([H])(C2=C([H])C3=C([H])C([H])=C([H])C([H])=C3C([H])=C2[H])[C@@]([H])(C(=O)OC([H])([H])[H])C1([H])[H]
[H]C1=C([H])C(=C([H])N1C1=C([H])C([H])=C(C([H])=C1[H])C(F)(F)F)C([H])([H])N1C([H])([H])C([H])([H])C([H])(C([H])([H])C(=O)N(C([H])([H])[H])C([H])([H])C([H])([H])C(=O)N2C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]N1C2=C3C([H])=C(OC4=C(C#N)C([H])=C([H])C(=C4[H])C([H])([H])N4C([H])=NC([H])=C4C([H])([H])N([H])[C@@]([H])(C1=O)C([H])([H])C([H])([H])[H])C([H])=C([H])C3=C([H])C([H])=C2[H]
[H]OC(=O)C([H])([H])C([H])([H])[C@]([H])(N([H])C(=O)C1=NC(=NC(N([H])C([H])([H])[C@]2([H])C([H])([H])N([H])C([H])([H])C2([H])[H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C(=O)N1C([H])([H])C([H])([H])N(C(=O)OC([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]C1=C2N(C3=C(C2=C([H])C(=C1[H])C(=O)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C([H])([H])N(C3([H])[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])S(=O)(=O)C([H])([H])C([H])([H])[H]
[H]N=C(N([H])C1=C([H])C([H])=C2C([H])=C([H])N(C2=C1[H])C([H])([H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H])C1=C([H])C([H])=C([H])S1
[H]OC([H])([H])C1=NC(=C([H])C(=C1[H])C1=C([H])C(=C([H])C([H])=C1[H])C1=NC2=C([H])C(=C(C([H])=C2N([H])C(=O)C1([H])[H])C(F)(F)F)C([H])([H])[H])C([H])([H])[H]
[H]N(C1=C([H])C([H])=C2N([H])C([H])=C([H])C2=C1C([H])([H])[H])C1=C(C#N)C([H])=NC([H])=C1C1=C([H])C([H])=C(O1)C([H])([H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]N(C(=O)[C@@]1([H])C([H])([H])N(C([H])([H])[C@]1([H])C(=O)N([H])C1=C(F)C([H])=C(C([H])=C1F)N1C([H])=C([H])C([H])=C([H])C1=O)S(=O)(=O)C([H])([H])[H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]OC1=NC2=C([H])C([H])=C([H])C([H])=C2N1[C@]1([H])C([H])([H])C([H])([H])N2[C@]([H])(C([H])([H])C([H])([H])C([H])([H])[C@@]2([H])C2([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C1([H])[H]
[H]N1C(=O)N(C2=NC(=NC([H])=C12)N1C([H])=NC2=C1C([H])=C([H])C([H])=C2[H])[C@@]1([H])C2=C(OC([H])([H])C1([H])[H])C(F)=C([H])C([H])=C2[H]
[H]N(C(=O)N(C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H])[C@]1([H])C([H])([H])C([H])([H])[C@]2(C3=C([H])C([H])=C([H])C(OC([H])([H])[H])=C3[H])C([H])([H])[C@]12[H])C1=C([H])C(=C(F)C([H])=C1[H])C(F)(F)F
[H]OC1=C([H])C([H])=C2C(=C1[H])C([H])([H])C([H])([H])[C@@]1([H])[C@]3([H])C([H])([H])[C@@]([H])(C([H])([H])C([H])([H])C([H])([H])SC#N)[C@]([H])(O[H])[C@@]3(C([H])([H])[H])C([H])([H])C([H])([H])[C@]21[H]
[H]N(C(=O)C1=NC(=C(N1C([H])([H])[H])C1=C([H])C([H])=C(Cl)C([H])=C1[H])C1=C([H])C([H])=C(Cl)C([H])=C1[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]N1N=NC(=N1)C1=C([H])C([H])=C([H])C([H])=C1C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1C(=O)N(N=C1C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]O[C@@]([H])(C([H])([H])C([H])([H])C([H])([H])[H])[C@@]([H])(N([H])C(=O)C([H])([H])N([H])C(=O)C1=C([H])C(=C([H])C([H])=C1N([H])C(=O)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C(F)(F)F)C([H])([H])N([H])C([H])([H])C1=C(C([H])=C(C([H])=C1[H])C([H])([H])[H])C([H])([H])[H]
[H]OC1=C([H])C([H])=C(C([H])=C1Cl)C(=O)N([H])\N=C(/[H])C1=C([H])C([H])=C(N([H])C(=O)C2([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C2=C([H])C([H])=C([H])C([H])=C12
[H]C1=C2N(C(=O)OC2=C(F)C([H])=C1C([H])([H])[H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])[C@@]1(C([H])([H])[H])C([H])([H])C([H])([H])[C@]([H])(OC([H])([H])C([H])([H])[H])C([H])([H])C1([H])[H]
CC1=C(CC(O)=O)C2=CC(F)=CC=C2N1C(=O)C1=CC(=CC=C1)C(F)(F)F
[H]C1=C([H])C([H])=C2C(OC3=C(C([H])=C(Br)C([H])=C3[H])[C@@]3([H])O[C@]([H])(C([H])([H])N4OC5=C4C([H])=C(C([H])=C5[H])N4C([H])([H])C([H])([H])OC([H])([H])C4([H])[H])C([H])([H])[C@@]23[H])=C1[H]
[H]N(C1=C(C([H])=C(C([H])=C1[H])S(=O)(=O)N([H])C(=O)C1=C([H])C([H])=C(C([H])=C1[H])N1C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H])[N+]([O-])=O)[C@@]([H])(C([H])([H])SC1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H]
[H]C1=C(N=C(N1C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)C([H])([H])[H])C1=C([H])N(C2=C1C([H])=C([H])C([H])=C2[H])C([H])([H])[H])C(F)(F)F
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[H]OC1=C2C(OC(C([H])([H])[H])(C([H])([H])[H])[C@@]3([H])C([H])([H])C([H])=C(C([H])([H])[H])C([H])([H])[C@@]23[H])=C([H])C(=C1[H])C([H])([H])C([H])([H])C#CC([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])(C([H])([H])OC([H])(C2=C([H])C([H])=C(F)C([H])=C2[H])C2=C([H])C([H])=C(F)C([H])=C2[H])C([H])([H])C1([H])[H]
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[H]N(C1=C([H])C2=C(C([H])=C1[H])C([H])=C([H])C1=C(C([H])=C(C([H])=N1)C1=C([H])N(N=C1[H])C([H])([H])[H])C2=O)S(=O)(=O)C1=C([H])N(C([H])=N1)C([H])([H])[H]
[H]C1=C([H])C2=C(S1)C(=NC(=N2)N(C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H])N(C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H]
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[H]OC1=C(C([H])=C(C([H])=C1[H])C([H])([H])C1=C(C([H])=C(OC([H])([H])P(=O)(O[H])O[H])C([H])=C1C([H])([H])[H])C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])OC([H])([H])[C@@]1([H])C([H])([H])[C@@]23C([H])([H])C([H])([H])[C@]1(OC([H])([H])[H])[C@]1([H])OC4=C(OC([H])([H])[H])C([H])=C([H])C5=C4[C@]21C([H])([H])C([H])([H])N(C([H])([H])C1([H])C([H])([H])C1([H])[H])[C@]3([H])C5([H])[H]
[H]N(C(=O)C([H])([H])C1([H])C([H])([H])C([H])([H])C(F)(F)C([H])([H])C1([H])[H])[C@]([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])N1C([H])([H])[C@]2([H])C([H])([H])N(C(=O)C3=C(N=C([H])N=C3C([H])([H])[H])C([H])([H])[H])C([H])([H])[C@]2([H])C1([H])[H]
[H]O[C@]([H])(C(=O)N([H])N([H])C(=O)C1=C([H])C([H])=C2C([H])=C([H])C([H])=C([H])C2=C1[H])[C@]([H])(N([H])[H])C([H])([H])SC([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N=C(N([H])[H])C1=C([H])C(N([H])[C@]([H])(C(=O)N([H])C2=C([H])C([H])=C(C([H])=C2[H])N2C(=O)C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C2=C([H])C([H])=C([H])C([H])=C2[H])=C([H])C([H])=C1[H]
[H]OC([H])([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])N([H])C(=O)C1=C([H])C([H])=C2N([H])C(=O)\C(=N/N([H])C3=C([H])C([H])=C(C([H])=C3[H])S(=O)(=O)N([H])[H])C2=C1[H]
[H]N1C2=C([H])C(=C([H])C([H])=C2OC([H])([H])C1=O)C([H])([H])N1C([H])([H])C([H])([H])C([H])(C2=C([H])C([H])=C(C([H])=C2[H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]OC1=C([H])C([H])=C(N([H])C2=NC3=C(C([H])=N2)C([H])([H])C(=O)N([H])C2=C([H])C([H])=C([H])C([H])=C32)C([H])=C1[H]
[H]OC(=O)C([H])([H])C1(C([H])([H])S[C@@]([H])(C2=C([H])C(\C([H])=C(/[H])C3=NC(=C([H])S3)C3([H])C([H])([H])C([H])([H])C3([H])[H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2C(O[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]C1=C2N(C(=C1C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C(=O)C(=C([H])N2C([H])([H])C1=C(F)C([H])=C([H])C([H])=C1[H])C(=O)OC([H])(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H]
[H]N(C(=O)C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C(=O)N1N=C(C([H])=C1[H])C([H])([H])[H]
[H]N(C([H])([H])[H])C([H])([H])[C@@]([H])(N1C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])C2([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])[C@@]([H])(C1([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])[C@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])[H]
[H]N(C([H])([H])[H])C([H])([H])C1=C([H])C(=C([H])C([H])=C1OC1=C([H])C([H])=C(Cl)C([H])=C1OC([H])([H])[H])C(=O)N(C([H])([H])[H])C([H])([H])[H]
[H]OC(=O)C([H])([H])[C@@]([H])(O[H])C([H])([H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=NC([H])=C1[H]
[H]N(C(=O)C1(N([H])C(=O)C(F)(F)F)C([H])([H])C1([H])[H])[C@@]([H])(C1=C([H])C([H])=C(C([H])=C1F)C1=C([H])C(Cl)=C([H])C([H])=C1C(=O)OC([H])([H])[H])C([H])([H])[H]
[H]N([H])C(=O)C1=C(SC2=C1C([H])([H])C([H])([H])C([H])([H])C2([H])[H])N([H])C(=O)C1=C(C([H])=C([H])C([H])=C1[H])C([H])([H])[H]
[H]N([H])C([H])([H])[C@]1([H])C([H])([H])[C@@]1(C(=O)N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC(=O)C(=O)N(C1=C([H])C([H])=C([H])C([H])=C1C(=O)O[H])C1=C2C([H])=C([H])C([H])=C([H])C2=C(C([H])=C1[H])C([H])([H])[C@@]([H])(N([H])C(=O)C([H])([H])[H])C(=O)N([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]N(C(=O)C1=C2N=C(OC2=C([H])C([H])=C1[H])N1[C@@]([H])(C([H])([H])[H])C([H])([H])OC([H])([H])[C@]1([H])C([H])([H])[H])C1([H])C([H])([H])[C@]2([H])N(C([H])([H])[H])[C@]([H])(C([H])([H])C([H])([H])C2([H])[H])C1([H])[H]
[H]N1C([H])([H])C([H])([H])N(C2=NC([H])=C([H])C([H])=C2I)C([H])([H])C1([H])[H]
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[H]N(C(=O)C([H])([H])N1C(=NC2=C([H])C([H])=C([H])C([H])=C12)C1=C([H])SC([H])=N1)C1=C([H])C([H])=C([H])C(Cl)=C1[H]
[H]OS(=O)(=O)C([H])([H])C([H])([H])N1C(=S)S\C(=C(\[H])C2=C([H])N(N=C2C2=C([H])C([H])=C3O[C@@]([H])(C([H])([H])[H])C([H])([H])C3=C2[H])C2=C([H])C([H])=C([H])C([H])=C2[H])C1=O
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[H]N(C([H])([H])C1([H])C([H])([H])C1([H])[H])S(=O)(=O)C1=C([H])C([H])=C2C(=C1[H])C([H])([H])C([H])([H])N([H])C([H])([H])C2([H])[H]
[H]OC(=O)C([H])([H])[C@@]1([H])C2=C(C([H])=C(OC([H])([H])C([H])([H])C3=C(OC(=N3)C3=C([H])C(F)=C([H])C([H])=C3[H])C([H])([H])[H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]OC1=C([H])C([H])=C2N(C3=C(C2=C1[H])C1=C(C(=O)N([H])C1=O)C(=C3[H])C1=C(Cl)C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])O[H]
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[H]N(C(=O)C1=C2N=C(N([H])C3=C([H])C([H])=C([H])C([H])=C3Cl)C3=C(SC([H])=C3[H])C2=C([H])C([H])=C1[H])C([H])([H])[H]
[H]ON([H])C(=O)[C@]([H])(N([H])S(=O)(=O)C1=C(F)C(F)=C(F)C(F)=C1F)C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H]
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[H]OC(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)C(N([H])C(=O)C(N([H])C(=O)[C@@]([H])(N(C([H])([H])C([H])=C([H])[H])C([H])([H])C([H])=C([H])[H])C([H])([H])C1=C([H])C([H])=C(O[H])C([H])=C1[H])(C([H])([H])[H])C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]C1=NC([H])=C(C([H])=N1)C([H])([H])C1=C([H])N(C(SC([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])=NC1=O)C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]O\C(\C(\[H])=C(/[H])\C(\[H])=C(/[H])C([H])([H])[H])=C1\C(=O)[C@@]2(C(=O)[C@@](O[H])(C([H])([H])[H])[C@@]1([H])[C@@]([H])([C@@]2([H])C(=O)C(\[H])=C(/[H])\C(\[H])=C(/[H])C([H])([H])[H])[C@@]1(OC(=O)C(=C1O[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C(C([H])=C1[H])N1C(=O)C([H])([H])C([H])([H])C([H])([H])C1([H])[H])[C@@]1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])N([H])C(=O)C1=C([H])C2=C(C([H])=C1[H])C(Cl)=C([H])N2[H]
[H]N(C(=O)N1C([H])([H])C([H])([H])C([H])(C([H])([H])N([H])C(=O)C2=C([H])C(Cl)=C([H])C([H])=C2C2([H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])N3C(=O)C([H])([H])OC4=C3C([H])=C([H])C([H])=C4[H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC1=C([H])C2=C(C3=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C([H])=C3OC([H])([H])[H])C3=C([H])C(O[H])=C(O[H])C([H])=C3OC2=C([H])C1=O
[H]N1C([H])([H])C2=C(SC(=C2[H])[N+]([O-])=O)C([H])([H])[C@]1([H])C([H])([H])[H]
[H]N([H])C(=NOC([H])([H])C1(C([H])([H])OC2=C([H])C(=C([H])C(=C2[H])C([H])([H])[H])C(=O)N(C([H])([H])C2=C([H])OC([H])=C2[H])C([H])([H])C2([H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H])N([H])[H]
[H]C1=C([H])C(=C([H])C(=O)N1C1=C([H])C([H])=C2C(=C1[H])N(C1=C2C([H])([H])C([H])([H])N(C([H])([H])[H])C1([H])[H])C([H])([H])[H])C1=C(Cl)C([H])=C(Cl)C([H])=C1[H]
[H]N=C(N([H])[H])N([H])C([H])([H])C([H])([H])C([H])([H])[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)C([H])([H])N([H])C(=O)[C@@]([H])(N([H])C(=O)C1=C([H])C([H])=C(N([H])[H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C(=O)N([H])[C@]([H])(C(=O)N([H])[H])C([H])([H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H]
[H]C1=C([H])[N+](=C([H])C([H])=C1C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[N+]1=C([H])C([H])=C(C([H])=C1[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]N=C(SC([H])([H])C([H])([H])C([H])([H])N1C(=O)C2=C(N3C4=C([H])C([H])=C([H])C([H])=C4C([H])([H])[C@]3([H])C3=C([H])C([H])=C([H])C4=C3N2C([H])=C4[H])C1=O)N([H])[H]
[H]O[C@@]([H])(C([H])([H])N([H])C(=O)C1=C([H])C2=C(C([H])=C1[H])C(=O)N(C2=O)C1=C([H])C([H])=C(C([H])=C1[H])[N+]([O-])=O)C([H])([H])N1C([H])([H])C([H])([H])N(C2=C(OC([H])(C([H])([H])[H])C([H])([H])[H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N(C1=NC(=O)[C@](S1)(C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[H])C1([H])C(C([H])([H])[H])(C([H])([H])[H])C1(C([H])([H])[H])C([H])([H])[H]
[H]OC1=C([H])C([H])=C(O[C@@]2([H])C3=C([H])C([H])=C([H])C([H])=C3C([H])([H])[C@@]2(O[H])C([H])([H])N([H])C([H])([H])[H])C(=C1[H])C([H])([H])[H]
[H]C1=C([H])C(=C([H])C(=C1[H])C([H])([H])[H])C1(C2=NN=C3N2C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C3([H])[H])C([H])([H])C([H])([H])C1([H])[H]
COC(=O)CN1CN(C2=CC=CC=C2)C2(CCN(CC3=CC=CC4=CC=CC=C34)CC2)C1=O
[H]C1=C([H])C([H])=C(OC([H])([H])C([H])([H])OC2=C([H])C([H])=C([H])C([H])=C2OC([H])(C([H])([H])[H])C([H])([H])[H])C(OC([H])([H])C([H])([H])[H])=C1[H]
[H]N(C1=NC2=C([H])C([H])=C([H])C([H])=C2OC1([H])[H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C([H])C([H])=C([H])C([H])=N2)C([H])([H])C1([H])[H]
[H]N=C(N([H])[H])C1=C([H])C(=C([H])C([H])=C1[H])C1=NO[C@@](C(=O)N([H])C2=NC([H])=C(C([H])=N2)C2=C([H])C([H])=C([H])C([H])=C2S(=O)(=O)N([H])[H])(C([H])([H])S(=O)(=O)C([H])([H])C([H])([H])[H])C1([H])[H]
[H]OC(=O)C1=C([H])C([H])=C([H])C([H])=C1C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1C(=O)C2=C(N=C1C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])=C([H])C([H])=C2[H]
[H]N(C(=O)[C@@]1([H])C([H])([H])OC([H])([H])C1([H])[H])C1=C([H])C(=C([H])C([H])=N1)C1=C([H])C(=NC([H])=C1[H])N([H])C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]C1=NC(=C([H])C([H])=C1[H])C([H])([H])C([H])([H])N(C1=C([H])C(=NC2=C1N(N=C2C1=C(Cl)C([H])=C(Cl)C([H])=C1[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C2=C([H])C(OC([H])([H])[H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N(N([H])C(=O)C([H])([H])OC1=C([H])C2=C(C([H])=C1[H])C(=C([H])C(=O)O2)C([H])([H])[H])C(\[H])=C1/C([H])=C(C([H])=C([H])C1=O)[N+]([O-])=O
CN1C(N)=N[C@@]2(CC(C)(C)CC3=C2C=C(C=C3)C2=CC(=CC=C2)C#N)C1=O
[H]N(C(=O)C(C1=C([H])C(=C([H])C([H])=C1[H])C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C(N2C([H])([H])C([H])([H])N(C(=O)C3=C([H])C([H])=C([H])C([H])=C3[H])C([H])([H])C2([H])[H])C(Cl)=C1[H]
[H]N(C(=O)C1=C([H])C(=C(Cl)C([H])=C1[H])C(F)(F)F)C1=C([H])C([H])=C([H])C(=C1[H])C1=C([H])C([H])=NC2=C([H])C(=NN12)C1=C([H])C([H])=NC([H])=C1[H]
[H]N(C(=O)N1C([H])([H])C([H])([H])N(C2=NC(=C(C([H])=C2C#N)C(=O)OC([H])([H])C([H])([H])[H])C(F)(F)F)C([H])([H])C1([H])[H])C1=C([H])C([H])=C([H])C([H])=C1Cl
OC1=CC=CC=C1C(=O)\C=C\C=C\C1=CC=C(C=C1)[N+]([O-])=O
[H]N(C1=C([H])C([H])=C([H])C2=C1N=C(O2)C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1N1N=NN=C1[H])C([H])([H])C(F)(F)C1=C([H])C([H])=C([H])C([H])=N1
[H]N([H])C(=O)[C@@]1([H])N(C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@]2([H])C([H])=C3C4=C([H])C([H])=C([H])C5=C4C(=C([H])N5[H])C([H])([H])[C@@]3([H])N(C([H])([H])[H])C2([H])[H])C([H])([H])C([H])([H])C2([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C1([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C(=C(C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)OC([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]O[C@]1([H])N(C(=N[H])N([H])[H])C([H])([H])C([H])([H])C([H])([H])[C@]1([H])N([H])C(=O)C([H])([H])N1C(=O)[C@](N([H])S(=O)(=O)C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])(C(=O)OC([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C1([H])[H]
[H]N([H])S(=O)(=O)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])N([H])C(=O)C1=C(F)C(F)=C(F)C(F)=C1F
[H]N(C1=NC(N([H])C2([H])C([H])([H])C2([H])[H])=C(C([H])=N1)C(F)(F)F)C1=C([H])C(F)=C(C([H])=C1OC([H])([H])[H])C(=O)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]C1=C([H])N(C2=NC(=C([H])C(=O)N12)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C(F)=C1[H]
[H]OC(=O)[C@@]([H])(N([H])C(=O)C1(C([H])([H])C([H])([H])N([H])C(=O)C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C(N([H])C(=O)C2=C(Cl)C([H])=C([H])C([H])=C2Cl)C([H])=C1[H]
[H]C1=NC(=C([H])C([H])=C1[H])[C@]([H])(C1=C([H])C([H])=C(Br)C([H])=C1[H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H]
[H]SC1=NN=C(N1N([H])C(=O)C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])SC(=N1)N([H])C(=O)C([H])([H])[H]
[H]\C(=C1/C2=C([H])C([H])=C([H])C(=C2C([H])([H])C1([H])[H])C([H])([H])[H])C1=C([H])C([H])=C([H])N=C1[H]
[H]O[C@]1(N([H])C(SC([H])([H])C([H])([H])[H])=C(C#N)[C@]([H])(C2=C([H])C([H])=C([H])C([H])=C2Cl)[C@@]1([H])C(=O)C1=C([H])C([H])=C([H])S1)C(F)(F)F
[H]N1C([H])([H])C([H])([H])C2=C(C3=C([H])C([H])=C([H])C([H])=C3N2C([H])([H])[H])C([H])([H])C1([H])[H]
[H]C1=NC2=C(C([H])=C([H])C(=C2[H])C(=O)N2C([H])([H])C([H])([H])C([H])([H])[C@]3([H])C4=C(C([H])=C([H])C(C#N)=C4[H])C([H])([H])[C@]23[H])C1([H])[H]
[H]OC(=O)[C@@]([H])(N([H])C(=O)[C@@]1([H])N(C(=O)[C@@]2([H])N(C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C3=C([H])C([H])=C(O[H])C([H])=C3[H])[C@@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])[H])C([H])([H])C3=C(N=C([H])N3[H])C2([H])[H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)C1=NC2=C(C([H])=C(F)C([H])=C2C(OC([H])([H])[H])=C1[H])N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]N1N=C(C2=C([H])C([H])=C([H])C([H])=C2C1=O)C([H])([H])C1=C([H])C([H])=C(F)C(=C1[H])C(=O)N1C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])S(=O)(=O)C([H])([H])C([H])([H])[H]
[H]N1C([H])([H])C([H])([H])C([H])(N(C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2SC([H])([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N([H])C1=C([H])C([H])=C([H])C(N([H])C(=O)N([H])[C@]2([H])N=C(C3=NC([H])=C([H])C([H])=C3[H])C3=C(C([H])=C([H])C([H])=C3[H])N(C2=O)C([H])([H])C(=O)C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])=C1[H]
[H]N(C1=C([H])C(=NS1)C([H])([H])[H])C1=NC([H])=C([H])N2C1=NC([H])=C2C1=C([H])N(N=C1[H])C([H])([H])[H]
[H]\C(C1=C([H])C([H])=C([H])C([H])=C1[H])=C1/C(=O)/C(=C(\[H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])N(C(=O)OC([H])([H])C([H])([H])[H])C1([H])[H]
[H]C([H])=C([H])C1=NN2N=C([H])C(=C2C([H])=C1[H])C1=C([H])C([H])=NC(=N1)N([H])C1([H])C([H])([H])C1([H])[H]
[H]C1=C(C#N)C([H])=C2SC(=NC2=N1)N1C([H])([H])C([H])([H])C([H])(N2C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]OC1=C([H])C([H])=C(N=C1[H])[C@@]([H])(C([H])([H])C([H])([H])[H])[C@@]([H])(C1=C([H])C([H])=C(O[H])C([H])=C1[H])C([H])([H])C([H])([H])[H]
[H]N1C([H])([H])C([H])([H])N(C(=O)N2C([H])([H])C([H])([H])C([H])([H])N([H])[C@@]2([H])C2=C([H])C(=C([H])C(=C2[H])C(F)(F)F)C(F)(F)F)[C@@]([H])(C2=C([H])C([H])=C(F)C([H])=C2C([H])([H])[H])C1([H])[H]
[H]N([C@]([H])(C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)C1=C(C([H])=C(Cl)C([H])=C1[H])S(=O)(=O)C1=C(F)C([H])=C([H])C([H])=C1F)C([H])([H])[H])S(=O)(=O)C(F)(F)F
[H]OC(=O)C1=C(C(=O)C2=C(O[H])C([H])=C(C([H])=C2O[H])C(=O)O[C@]2([H])C([H])([H])[C@]([H])(C([H])([H])N([H])[H])C([H])([H])[C@@]2([H])N([H])C(=O)C2=C([H])C([H])=C(O[H])C([H])=C2[H])C(O[H])=C([H])C([H])=C1[H]
[H]OC(=O)C([H])([H])C([H])([H])C1=C(N([H])C2=C1C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C(\[H])=C1/C(=O)N([H])C2=C([H])C([H])=C(C([H])=C12)S(=O)(=O)C([H])([H])C([H])([H])[H]
[H]OC(=O)[C@]([H])(N([H])S(=O)(=O)C1=C(C([H])=C(C([H])=C1C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])N([H])C(=O)C1=C([H])SC([H])=C1[H]
[H]SC1=NN=C(N1N([H])[H])C([H])([H])C1=C(SC2=C1C([H])([H])C([H])([H])C([H])([H])C2([H])[H])N([H])C(=O)C([H])([H])[H]
[H]OC1=C(O[H])C([H])=C2C(=C1[H])C([H])([H])C([H])([H])[C@@]([H])(N([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C2([H])[H]
[H]C1=C([H])C(=C(C(=C1[H])C(F)(F)F)C([H])([H])[H])C([H])([H])N1C2=NC(=C([H])C(=O)N2C(=C1C([H])([H])[H])C([H])([H])[H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]N1C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])[C@]([H])(C1=C([H])C([H])=C([H])C(F)=C1F)C([H])([H])OC([H])([H])C1=C([H])C(=C([H])C(=C1[H])C(F)(F)F)C(F)(F)F
[H]C1=C([H])C(=C([H])C(=C1[H])C([H])([H])[N@@+]12C([H])([H])C([H])([H])[C@@]([H])(C([H])([H])C1([H])[H])C([H])([H])C2([H])[H])C1=C([H])C([H])=C([H])C(=C1[H])C([H])([H])[N@@+]12C([H])([H])C([H])([H])[C@@]([H])(C([H])([H])C1([H])[H])C([H])([H])C2([H])[H]
[H]OC(=O)C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C1=C(SC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C2=C([H])C(OC([H])([H])C3=C([H])C([H])=C(C([H])=N3)C([H])([H])[H])=C([H])C([H])=C2N1C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C(F)C([H])=N1
[H]N(C(=O)C1=C([H])C2=C([H])C([H])=C([H])C([H])=C2N=C1[H])[C@@]([H])(C(=O)N(C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H]
[H]OC1=C([H])C([H])=C2C(=C1[H])[C@@]1(C([H])([H])[H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])C([H])=C([H])[H])[C@@]([H])(C2([H])[H])[C@@]1([H])C([H])([H])[H]
CCC1=NN2C(C=CC=C2C2=C(OC)C=C(OC)C=C2OC)=C1N(CC1CC1)CC1CCOCC1
[H]O[C@@]1([H])[C@@]([H])(O[C@]([H])(C(=O)N([H])C([H])([H])[H])[C@@]1([H])O[H])N1C([H])=NC2=C1C(=O)N(C(=O)N2C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]N(C1=C2C([H])=C(C([H])=C([H])C2=NC([H])=N1)C1=C([H])C([H])=C(O1)C([H])([H])OC([H])([H])C([H])([H])S(=O)(=O)C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C(OC([H])([H])C2=C([H])C(F)=C([H])C([H])=C2[H])C(Cl)=C1[H]
[H]OC(C([H])([H])C([H])([H])[H])(C([H])([H])C([H])([H])[H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])[C@]([H])(C2=C([H])C([H])=C(Cl)C(Cl)=C2[H])C([H])([H])N(C(=O)C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N(\N=C(/[H])C1=C([H])C([H])=C(OC([H])([H])C(=O)N([H])C2=C([H])C([H])=C(C([H])=C2[H])C([H])([H])[H])C([H])=C1[H])C(=O)C([H])([H])SC([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H]
[H]OC1=C(C([H])=C([H])C([H])=C1[H])C1=C([H])C(=C(C#N)C(=N1)N([H])[H])C1=C([H])C([H])=C(N([H])C(=O)C([H])([H])C([H])([H])N2C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])=C1[H]
[H]N([H])[C@@]1([H])C([H])([H])N(C2=NC3=C(N2C([H])([H])C([H])=C(C([H])([H])[H])C([H])([H])[H])C(=O)N(C(=O)N3C([H])([H])[H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C1([H])[H]
[H]OC([H])([H])[C@]([H])(N1C([H])=C(Cl)N=C(N([H])C2=C(C([H])=C(OC([H])([H])[H])C(=C2[H])C([H])([H])[H])C([H])([H])[H])C1=O)C1([H])C([H])([H])C1([H])[H]
[H]O[C@@]1([H])C([H])([H])[C@@]2([H])N(C([H])([H])[H])[C@]1([H])C([H])([H])[C@@]([H])(O[C@]([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C(Cl)C([H])=C1[H])C2([H])[H]
[H]O[C@]([H])(C1=C([H])C([H])=C([H])N=C1[H])C([H])([H])N([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C(N([H])S(=O)(=O)C2=C([H])C([H])=C(C([H])=C2[H])N2N=C([H])N(C2=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])=C1[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C1=C(C(=O)C(=O)C2=C([H])C([H])=C([H])C([H])=C12)C([H])([H])C1=C([H])C([H])=C(OC([H])([H])C(=O)OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])=C1[H]
[H]N(C(=O)N1C([H])([H])[C@@]([H])(N(C2=C([H])C(=C(C#N)C([H])=C2[H])C(F)(F)F)C([H])([H])[C@@]1([H])C([H])([H])[H])C([H])([H])[H])C1=C([H])N=C(C([H])=C1[H])C(=O)C([H])([H])[H]
[H]ON([H])C(=O)[C@]1([H])N(C([H])([H])[C@@]([H])(SC1(C([H])([H])[H])C([H])([H])[H])C([H])([H])N([H])[H])S(=O)(=O)C1=C([H])C([H])=C(OC([H])([H])C#CC([H])([H])[H])C([H])=C1[H]
[H]OC([H])([H])[C@@]1([H])O[C@@]([H])(C([H])([H])N2C([H])=NC3=C(N=C([H])N=C23)N([H])[C@]2([H])C([H])([H])[C@]3([H])C([H])([H])[C@@]2([H])C([H])([H])[C@@]3([H])O[H])[C@]([H])(O[H])[C@]1([H])O[H]
[H]C1=C(OC([H])([H])[H])C([H])=C(OC([H])([H])[H])C(=C1[H])C1=NC(=C(N(C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[H])C(=O)N1C([H])([H])C1([H])C([H])([H])C1([H])[H])C([H])([H])[H]
FC1=CC=C(C=C1)C(=O)NCCN1CCC2(CC1)N(CNC2=O)C1=CC=C(Br)C=C1
[H]OC(=O)C([H])([H])C([H])([H])C(=O)N1C([H])=C(C2=C1C([H])=C([H])C([H])=C2[H])C([H])([H])[C@@]([H])(N([H])C(=O)C([H])([H])[C@@]1([H])N([H])C(=O)[C@@]2([H])N(C1=O)[C@@]1([H])C([H])([H])C([H])([H])[C@]2([H])C([H])([H])C1([H])[H])C(=O)N([H])[C@@]([H])(C(=O)N(C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C1=C2SC(=NC2=C([H])C2=C1C([H])([H])[C@@]1([H])N(C([H])([H])C3([H])C([H])([H])C3([H])[H])C([H])([H])C([H])([H])[C@@]22C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@@]12[H])N(C([H])([H])[H])C([H])([H])[H]
[H]OC([H])([H])[C@@]1([H])O[C@@]([H])(N2C([H])=NC3=C2N=C(Cl)N=C3N([H])[C@@]([H])(C([H])([H])[H])C([H])([H])OC2=C([H])C([H])=C([H])C([H])=C2[H])[C@]([H])(O[H])[C@]1([H])O[H]
[H]O[C@@]1(C2=C([H])C([H])=NC([H])=C2[H])C2=C([H])C([H])=C(C([H])=C2C([H])([H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C(F)C(F)=C1[H]
[H]N(N([H])C(=O)C([H])([H])SC1=NN=C(N1N([H])C(=O)C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C(SC2=C1C([H])([H])C([H])([H])C([H])([H])C2([H])[H])N([H])C(=O)C([H])([H])[H])C(=O)C([H])([H])Cl
[H]N(C(=O)C1=C([H])[N+]([O-])=C(C([H])=C1[H])S(=O)(=O)C([H])([H])C([H])([H])[H])C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]N(C(=O)C1=C(N=C([H])N1C([H])([H])[H])N([H])C([H])([H])C1=C([H])C([H])=NC([H])=C1[H])C1=C([H])C([H])=C(Cl)C(=C1[H])C(F)(F)F
[H]N1N=C(C2=C(C3=C([H])C(Cl)=C([H])C(=C3N=C12)C([H])([H])[H])C([H])([H])N1[C@@]2([H])C([H])([H])C([H])([H])[C@]1([H])C([H])([H])C2([H])[H])C([H])([H])[H]
[H]N(C(=O)C1=C([H])C(OC([H])([H])C([H])([H])C2=C([H])C([H])=C(Cl)C([H])=C2Cl)=C(OC([H])([H])[H])C([H])=C1[H])C([H])([H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(C(Cl)=O)C(=O)O[C@]1([H])C([H])([H])C([H])([H])[C@@]2(OC2([H])[H])[C@]([H])([C@]1([H])OC([H])([H])[H])[C@]1(O[C@]1([H])C([H])([H])C([H])=C(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])C(=C([H])C(Cl)=C1Cl)[C@]1([H])[C@]([H])(C([H])([H])[N+]([H])(C([H])([H])[H])C([H])([H])[H])[C@]2([H])C([H])([H])C([H])([H])[C@@]1([H])C([H])([H])C2([H])[H]
[H]N=C(N([H])[H])N([H])C([H])([H])C([H])([H])C([H])([H])[C@@]([H])(N([H])C(=O)C([H])([H])N1C(=O)C([H])([H])N(C([H])([H])C1([H])[H])S(=O)(=O)C1=C([H])C([H])=C([H])C([H])=C1[H])C(=O)C1=NC([H])=C([H])S1
[H]N(C(=O)N([H])[C@]1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])[C@@]([H])(C([H])([H])C2=C([H])C([H])=C(F)C([H])=C2[H])C1([H])[H])C1=C([H])C([H])=C([H])C(=C1[H])C(=O)C([H])([H])[H]
[H]C1=NN=C(N1C([H])([H])[H])[C@]([H])(N(C1=C([H])C(Cl)=C(C#N)C([H])=C1[H])C([H])([H])C1=C(Cl)C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]N(C([H])([H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])OC2=C([H])C([H])=C([H])C(F)=C2[H])C([H])([H])C1([H])[H])S(=O)(=O)C1=C([H])C([H])=C([H])C(Cl)=C1[H]
[H]N=C(N([H])[H])C1=C([H])C(=C([H])C([H])=C1[H])C([H])([H])[C@]([H])(N([H])S(=O)(=O)C1=C([H])C([H])=C([H])C(N([H])C([H])([H])C([H])([H])C([H])([H])N([H])[H])=C1[H])C(=O)N1C([H])([H])C([H])([H])C([H])(C([H])([H])C([H])([H])N([H])[H])C([H])([H])C1([H])[H]
[H]ON([H])C(=O)C(\[H])=C(/[H])C1=C([H])C2=C(C([H])=C1[H])C([H])([H])N(C2=O)C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=NC([H])=C1[H]
[H]N(C(=O)C1=C([H])C([H])=C(C([H])=C1[H])[S@](=O)C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C(=O)N1C2=C([H])C([H])=C([H])C([H])=C2C([H])([H])[C@@]2(C([H])=C([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]OC1=C([H])C([H])=C(\C([H])=C2\C(=O)C(C3=C4C(=NC5=C4C([H])=C([H])C([H])=C5[H])\C(=C(\[H])C4=C([H])C([H])=C(O[H])C([H])=C4[H])C3=O)=C3C2=NC2=C3C([H])=C([H])C([H])=C2[H])C([H])=C1[H]
[H]N(C([H])([H])[H])[C@]([H])(C([H])([H])C1=C(OC([H])([H])[H])C([H])=C(SC([H])([H])C([H])([H])C([H])([H])[H])C(OC([H])([H])[H])=C1[H])C([H])([H])C([H])([H])[H]
[H]N(C(=O)C1=NC(SC2=NN=C([H])N2[H])=C([H])C([H])=C1SC1=C([H])C([H])=C([H])C(=C1[H])C([H])([H])[H])C1=NC([H])=C([H])S1
[H]N(C(=O)C(\[H])=C1\C2=C(C([H])=C([H])C([H])=C2[H])N(C(=O)C2=C(Cl)C([H])=C(C([H])=C2[H])N2C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C2([H])[H])C([H])([H])C([H])([H])C1(F)F)C([H])([H])C1=C([H])C([H])=C([H])C([H])=N1
[H]O[C@@]([H])([C@@]([H])(N([H])C(=O)[C@]1([H])C([H])([H])N(C(=O)C1([H])[H])C([H])([H])C([H])([H])OC([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C1=C([H])C(F)=C([H])C(F)=C1[H])[C@]1([H])N([H])C([H])([H])[C@]([H])(OC([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C1([H])[H]
[H]C1=NC(=C(O1)C1=NN=C(SC([H])([H])C([H])([H])C([H])([H])N2C([H])([H])[C@@]3([H])C([H])([H])[C@@]3(C3=C([H])C([H])=C(OC(F)(F)F)C([H])=C3[H])C2([H])[H])N1C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)C1=C(OC([H])([H])C([H])([H])F)C([H])=C([H])C(=C1[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C2=C(C([H])=C(OC([H])([H])[H])C(OC([H])([H])[H])=C2[H])C([H])([H])C1([H])[H]
[H]N(C([H])([H])[H])S(=O)(=O)C1=C([H])C([H])=C2N([H])C(=O)\C(=C(\[H])C3=C(C4=C(N3[H])C([H])([H])C([H])([H])C([H])([H])C4([H])[H])C([H])([H])C([H])([H])C([H])([H])N3C([H])([H])C([H])([H])N(C([H])([H])C(=O)OC([H])([H])C([H])([H])[H])C([H])([H])C3([H])[H])C2=C1[H]
[H]OC1(C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])[C@@]([H])(C(=N\OC([H])([H])[H])\C([H])([H])OC([H])([H])C(\[H])=C(/[H])C2=C([H])C(=C([H])C(=C2[H])C(F)(F)F)C(F)(F)F)C2=C([H])C(Cl)=C(Cl)C([H])=C2[H])C([H])([H])C1([H])[H]
CCSc1ncc(C)c(n1)-c1c[nH]c(c1)C(=O)N[C@H](CO)c1ccccc1
[H]C1=C([H])C([H])=C(S1)C1=NN(C2=C([H])C([H])=C([H])C([H])=C2[H])[C@]([H])(C2=C([H])C([H])=C(OC([H])([H])[H])C([H])=C2[H])C1([H])[H]
[H]OC1=NC([H])=C([H])N1C([H])([H])[C@](O[H])(C1=C([H])C(O[C@@]2([H])C([H])([H])OC([H])([H])C2([H])[H])=C(OC([H])([H])[H])C([H])=C1[H])C([H])([H])[H]
[H]N(C1=NC(=NC(=N1)N([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C(F)C([H])=C1[H])N([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C(F)C([H])=C1[H])C([H])([H])C([H])([H])OC([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)[C@@]([H])(C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)C1([H])C([H])([H])C1([H])[H])C([H])([H])C1([H])C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C1=NC2=C(S1)C([H])([H])C([H])([H])C([H])([H])C2([H])[H]
[H]N(C1=NC([H])=NC2=C([H])C(OC([H])([H])C([H])([H])C([H])([H])N3C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C3([H])[H])=C(OC([H])([H])[H])C([H])=C12)C1=C([H])C([H])=C(C([H])=C1F)C1=NC2=C(S1)C([H])=C(Cl)C([H])=C2[H]
[H]\C(=C(\[H])[C@@]1([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N=C(N([H])[H])C1=C([H])C([H])=C([H])C(=C1[H])C([H])([H])[C@]([H])(N([H])C(=O)[C@@]1([H])N2C(=O)C([H])([H])N(C(=O)C([H])([H])C([H])([H])C3=C([H])C([H])=C([H])C([H])=C3[H])C([H])([H])[C@]2([H])C([H])([H])C1([H])[H])C(=O)C1=NC2=C(C([H])=C([H])C([H])=C2[H])N1C([H])([H])[H]
[H]C1=C([H])N2C(=C1[H])C(OC(=O)N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H])=C(OC1=C([H])C([H])=C([H])C([H])=C21)C1=C([H])C(F)=C([H])C(F)=C1[H]
[H]OC1=NC2=C([H])C(Cl)=C(C([H])=C2C(OC([H])([H])C([H])([H])[C@]2([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[N+]2([H])[H])=C1C1=C([H])C(=C([H])C(=C1[H])C([H])([H])[H])C([H])([H])[H])C(=O)N([H])C1=C([H])C([H])=C([H])N=C1[H]
[H]C1=NC(=C(C([H])=C1[H])[C@@]([H])(C#N)N1C([H])([H])C([H])([H])N(C(=O)C([H])([H])OC([H])(C2=C([H])C([H])=C([H])C([H])=C2[H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H])C([H])([H])[H]
[H]N(C(=O)C([H])([H])C([H])([H])C([H])([H])[H])C1=NN(C2=C1C([H])=C1C([H])=C([H])C(=C([H])C1=N2)C([H])([H])[H])C([H])([H])[H]
OC[C@H](NC(=O)[C@H]1C[C@@H]1C1=CC=C(F)C=C1)C1=CC=C(OC2CCC2)N=C1
[H]OC(=O)C([H])([H])[C@@]([H])(N([H])C(=O)C([H])([H])C([H])([H])N([H])C(=O)C1=C([H])C2=C([H])C(=C([H])C([H])=C2O1)C(=N[H])N([H])[H])C(F)(F)F
[H]OC1=C2C([H])=C([H])C([H])=C([H])C2=C(N([H])S(=O)(=O)C2=C(C([H])=C(C([H])=C2[H])C([H])([H])[H])C([H])([H])[H])C([H])=C1Cl
[H]OC(=O)C([H])([H])N1C(=S)S\C(=C(\[H])C2=C([H])C([H])=C(O2)C2=C(C([H])=C([H])C([H])=C2[H])[N+]([O-])=O)C1=O
CC1=C(NC2=C3N=CN(C4O[C@H](CO)[C@@H](O)[C@H]4O)C3=NC=N2)C=CC=C1
NC(CCC(C1=CC=CC=C1)(C1=CC=CC=C1)C1=CC=C(O)C=C1)C(O)=O
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[H]OC(=O)[C@@]([H])(N([H])C(=O)C1=C([H])C([H])=C([H])C2=C1C([H])([H])C([H])([H])C([H])([H])[C@]2([H])N([H])C(=O)[C@@]([H])(N([H])[H])C([H])([H])S[H])C([H])([H])C([H])([H])SC([H])([H])[H]
[H]N(C1=C2C([H])=C(C([H])=C([H])C2=NC([H])=N1)C1=C([H])C2=C(OC([H])([H])O2)C([H])=C1[H])C([H])([H])C1=C([H])C(=C([H])C([H])=C1[H])C([H])([H])[H]
[H]N(C(=O)C([H])([H])C([H])([H])C([H])([H])[H])[C@]1([H])C2=C([H])C(=O)C(SC([H])([H])[H])=C([H])C([H])=C2C2=C(C([H])=C(OC(=O)C([H])([H])[H])C(OC([H])([H])[H])=C2OC([H])([H])[H])C([H])([H])C1([H])[H]
[H]N([H])C(=O)C1=NN(C2=C1C([H])([H])C([H])([H])C1=C([H])N=C(N=C21)N([H])C1=C([H])C([H])=C(C([H])=C1OC([H])([H])[H])N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H])C([H])([H])[H]
[H]OC(=O)C1=C(O[H])N=C2C([H])=C([H])C([H])=C([H])C2=C1C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1C2=C(N=C1C([H])([H])C([H])([H])C([H])([H])[H])C(=C([H])C(=N2)C([H])([H])[H])C([H])([H])[H]
[H]C1=C(ON=C1C([H])([H])[H])[C@@]([H])(N(C1=C([H])C(Cl)=C(C#N)C([H])=C1[H])C([H])([H])C1=C(Cl)C([H])=C([H])C([H])=C1[H])C([H])([H])[H]
[H]N(C(=O)C([H])([H])[H])C([H])([H])C([H])([H])N([H])C(=O)[C@@]1([H])N(C(=O)N(C2=C([H])C([H])=C([H])C([H])=C2[H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])N(C(=O)N(C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C1([H])[H]
[H]N(C([H])([H])C([H])([H])OC1=C([H])C(F)=C([H])C2=C1OC([H])([H])C([H])([H])C2=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1=C([H])C2=C(OC([H])([H])O2)C([H])=C1[H]
[H]N(C(=O)C([H])([H])C([H])([H])C(=O)O[C@]1([H])C2=C(C([H])=C3OC([H])([H])OC3=C2[H])[C@]([H])(C2=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C(OC([H])([H])[H])=C2[H])[C@]2([H])C(=O)OC([H])([H])[C@@]12[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=O)[C@]([H])(C1=C([H])C(F)=C(C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H]
[H]OC1=C2C([H])=C([H])C([H])=C(OS(=O)(=O)C3=C([H])C([H])=C(C([H])=C3[H])C([H])([H])[H])C2=C([H])C([H])=C1[H]
[H]N(C(=O)C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])[C@]([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[C@@]([H])(N1C([H])([H])C([H])([H])C([H])(N2C(=NN=C2C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H])C([H])([H])[H]
[H]C1=C([H])C([H])=C(C(=C1[H])[C@@]([H])(N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H])C([H])([H])N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H])C(F)(F)F
[H]N1C([H])([H])C([H])(OC2=C(OC3=C([H])C([H])=C([H])C(Cl)=C3Cl)C([H])=C([H])C([H])=C2F)C1([H])[H]
[H]N(\C(=N/C#N)N1C([H])([H])C([H])([H])C(=C2C3=C(C([H])=C(Br)C([H])=N3)C([H])([H])C([H])([H])C3=C2C([H])=C([H])C(Cl)=C3[H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]N([H])[C@]([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])N1C(=O)N(C(=C(C1=O)C1=C([H])C([H])=C([H])C(OC([H])([H])[H])=C1F)C([H])([H])[H])C([H])([H])C1=C(C([H])=C([H])C([H])=C1F)C(F)(F)F
[H]N([H])C(=O)C1=NN(C2=C1C([H])([H])C([H])([H])C1=C([H])N=C(N=C21)N([H])C1=C(OC(F)(F)F)C([H])=C([H])C(N([H])C2([H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C2([H])[H])=C1[H])C([H])([H])[H]
[H]OC(=O)C([H])([H])[C@]([H])(C([H])([H])[H])C([H])([H])C(=O)N([H])[C@@]([H])(C([H])([H])[H])[C@]([H])(C1=C([H])C(F)=C(C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C(Cl)C(Cl)=C1[H]
[H]N(C(=O)N1C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])[C@]1([H])C2=C(C([H])=C(Br)C([H])=N2)C([H])([H])C([H])([H])C2=C1C([H])=C([H])C(Cl)=C2[H])C1=C([H])C([H])=C([H])[N+]([O-])=C1[H]
[H]OC1=C([H])C([H])=C([H])C2=C1N=C(N=C2N(C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H])N([H])C1=C(C([H])=C([H])C([H])=C1[H])C([H])([H])[H]
[H]N([H])[C@@]1([H])C([H])([H])N(C2=NC3=C(C([H])=C(Br)C([H])=C3[H])C(=O)N2C([H])([H])C2=C(C#N)C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C1([H])[H]
[H]OC(=O)[C@]12C([H])([H])N(C(=O)C(=C([H])[H])C3=C([H])C([H])=C([H])C([H])=C3OC([H])([H])[H])C([H])([H])[C@@]1([H])[C@]1(C3=C([H])C([H])=C([H])C([H])=C3[H])C3=C([H])C([H])=C([H])C([H])=C3[C@@]2([H])C([H])([H])C1([H])[H]
[H]O[C@]([H])(C([H])([H])N([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])N1N(C(=O)C(C(=O)C([H])([H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])=C1C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)N1C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C(=O)OC([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1C([H])([H])[H])C(=O)N1C2=C(C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N=C(SC([H])([H])C([H])([H])C([H])([H])C1=C([H])N([H])C([H])=N1)N([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C(Br)C([H])=C1[H]
[H]OC1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[C@]([H])(N([H])[H])C(=O)N([H])[C@@]([H])(C(=O)N([H])C([H])([H])C(=O)N([H])[C@]([H])(C(=O)N([H])C([H])([H])C(=O)N1C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)OC([H])([H])C1=C([H])C(=C([H])C(=C1[H])C(F)(F)F)C(F)(F)F)C([H])([H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H]
[H]OC([H])([H])[C@@]1([H])OC2=C(OC1([H])[H])C(=C([H])C([H])=C2[H])N1C([H])([H])C([H])([H])N([H])C([H])([H])C1([H])[H]
[H]OC(=O)C1=C(C(OC2=C3C(=O)O[C@@](OC([H])([H])[H])(C3=C([H])C(OC([H])([H])[H])=C2[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])=C(O[H])C([H])=C1O[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]N([H])C(=O)N([H])C([H])([H])C([H])([H])C([H])([H])[C@@]([H])(N([H])C(=O)[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)C([H])([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])=O
CC1=C(Cl)C(C)=C2C(N)=C(SC2=N1)C(=O)NCC1=CC=CC(F)=C1F
[H]N(C(=O)C1=C(N(C2=C([H])C(OC([H])([H])OC([H])([H])[H])=C([H])C([H])=C12)C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C(F)=C(F)C([H])=C1[H]
[H]N([H])C1=NC2=C(OC([H])([H])C([H])([H])C([H])([H])N([H])C(=O)C3=C([H])C([H])=C4OC([H])([H])OC4=C3[H])C([H])=C([H])C([H])=C2C([H])=C1[H]
[H]O[C@@]1(C2=C([H])C([H])=C3C([H])=C([H])N(C3=C2[H])S(=O)(=O)C2=C([H])C([H])=C([H])C3=C([H])C([H])=C([H])C([H])=C23)C([H])([H])C([H])([H])N2C([H])([H])C([H])([H])C([H])([H])[C@@]2([H])C1([H])[H]
[H]OC(=O)C([H])([H])[C@]1([H])N([H])C2=C([H])C([H])=C(C([H])=C2C([H])([H])N(C1=O)C([H])([H])[H])C(=O)N(C([H])([H])C1=NC2=C(N1[H])C([H])=C([H])C([H])=C2[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]OC1=C(C([H])=C(Cl)C([H])=C1[H])C1=C([H])C([H])=C(O1)C(=O)N([H])C(=N[H])N([H])[H]
[H]N([H])C(=NC([H])([H])C([H])([H])C([H])([H])[C@@]([H])(N([H])C(=O)[C@]([H])(N([H])C(=O)C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])SC([H])([H])[H])C(=O)N([H])[C@@]([H])(C(=O)N([H])[C@@]([H])(C(=O)N([H])C([H])([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])N([H])[H]
[H]N(C(=O)N1C([H])([H])C([H])([H])N(C2=NC([H])=NC3=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C([H])=C23)C([H])([H])C1([H])[H])C1=C([H])C([H])=C(Cl)C(=C1[H])[N+]([O-])=O
[H]OC(C1=C([H])C([H])=C2C([H])=C(N([H])C2=C1[H])C1=NN([H])C2=C1SC([H])=C2[H])(C([H])([H])[H])C([H])([H])[H]
[H]N([H])C(=O)C1=C(OC([H])([H])[H])C([H])=C2N=C([H])C([H])=C(OC3=C([H])C4=C(C([H])=C3[H])N(C(=O)N([H])C3=C([H])C([H])=C(Cl)C([H])=C3[H])C([H])([H])C([H])([H])O4)C2=C1[H]
[H]N1C(=NC(=C1C1=C([H])C([H])=C([H])C(=N1)C([H])([H])[H])C1=C([H])C([H])=C2N=C([H])C([H])=NC2=C1[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C([H])([H])C(=O)N1C([H])([H])[C@@]([H])(F)C([H])([H])[C@@]1([H])C#N)C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C(=O)N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N1C([H])([H])C([H])([H])N(C2=NC([H])=C(N3C2=NC([H])=C3C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]O[C@]1(C2=C(OC([H])([H])[H])C([H])=C([H])C([H])=C2[H])C([H])([H])[N@]2C([H])([H])C([H])([H])[C@]1([H])C([H])([H])C2([H])[H]
[H]N(C1=NN=C(O1)C1=C([H])C([H])=C([H])N=C1C([H])([H])C([H])([H])C1=C([H])C([H])=NC([H])=C1[H])C1=C([H])C([H])=C([H])C(OC([H])([H])[H])=C1[H]
[H]N(C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])[C@]([H])(C(=O)N1C([H])([H])C([H])([H])C([H])(C([H])([H])N(C2=C([H])C([H])=C([H])C([H])=C2[H])S(=O)(=O)C([H])([H])[H])C([H])([H])C1([H])[H])C([H])([H])OC([H])([H])C1=C([H])C(Cl)=C(Cl)C([H])=C1[H]
[H]OC([H])([H])C([H])([H])N1C([H])([H])C2=C(N(C3=C([H])C(=C([H])C([H])=C23)N2C([H])=C([H])C(OC([H])([H])C3=C([H])C([H])=C([H])C([H])=C3[H])=C([H])C2=O)C([H])([H])[H])C([H])([H])C1([H])[H]
CCNc1ncc(C)c(n1)-c1c[nH]c(c1)C(=O)NCc1ccccc1F
CCCCC1=CC2=C(CC(C2)NC[C@H](O)C2=C3C=CC(=O)NC3=C(O)C=C2)C=C1
[H]C1=C([H])N(C([H])=N1)C([H])([H])C1=C([H])C([H])=C(Br)N=C1[H]
[H]SC1=NN=C(N1N([H])C(=O)C([H])([H])[H])C([H])([H])C1=C(SC2=C1C([H])([H])C([H])([H])C([H])([H])C2([H])[H])N([H])C(=O)C([H])([H])Cl
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[H]N(C(=O)C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C(F)C(N([H])C2=C([H])C([H])=C3C(=C2[H])C([H])([H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2C3=O)=C1[H]
[H]OC(=O)C([H])([H])C([H])([H])C([H])([H])N([H])[H]
[H]N([H])C1=C([H])C(=NC([H])=N1)N1C(=NC2=C1C([H])=C([H])C([H])=C2[H])N([H])C1=C([H])C(N([H])C(=O)C2=C([H])C(Cl)=C(C([H])=C2[H])C([H])([H])N2C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])[H])C([H])([H])C2([H])[H])=C([H])C([H])=C1C([H])([H])[H]
CN1C(=O)C(CC2=CC=C(F)C=C2)=CC2=CN=NC(C3=C(F)C=C(F)C=C3)=C12
[H]OC(=O)C1=C(C(=O)N([H])C2=C([H])C([H])=C(OC([H])([H])C3=C(Cl)C([H])=C([H])C([H])=C3F)C(Cl)=C2[H])C([H])([H])OC1([H])[H]
[H]O[C@@]([H])([C@@]([H])(OC([H])([H])C(\[H])=C(/[H])C1=C(ON=C1C([H])([H])[H])C([H])([H])[H])C(=O)N([H])[C@@]1([H])C2=C([H])C([H])=C([H])C([H])=C2C([H])([H])[C@@]1([H])O[H])[C@@]([H])(O[H])[C@@]([H])(OC([H])([H])C(\[H])=C(/[H])C1=C(ON=C1C([H])([H])[H])C([H])([H])[H])C(=O)N([H])[C@@]1([H])C2=C(C([H])=C([H])C([H])=C2[H])C([H])([H])[C@@]1([H])O[H]
[H]N(C(=O)C1=C([H])C2=C([H])N=C(C([H])=C2N1[H])C1=C(N([H])N=C1[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C(OC([H])([H])[H])=C1[H]
[H]N(C(=O)C1=C(N([H])C(=O)C2=C(Cl)C([H])=C(S2)C([H])([H])N2C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C2([H])[H])C([H])=C([H])C(Cl)=C1[H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]N(C1=NC(=C([H])C([H])=N1)C1=C2C([H])=C([H])C(=NN2N=C1[H])N([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C1([H])C([H])([H])C1([H])[H]
[H]N1C([H])([H])[C@]([H])(F)[C@]([H])(C([H])([H])N(C(=O)[C@@]2([H])OC([H])([H])C([H])([H])C2([H])[H])[C@@]([H])(C2=NC(=NN2C([H])([H])C2=C([H])C([H])=C([H])C(F)=C2[H])C2=C(F)C([H])=C([H])C(F)=C2[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C1([H])[H]
[H]OC1=C([H])C2=C([H])C([H])=C(C([H])=C2C(=C1[H])C([H])([H])C([H])([H])[H])C1=C([H])C(F)=C(O[H])C([H])=C1[H]
[H]N(C([H])([H])C1=C([H])C([H])=C([H])O1)S(=O)(=O)C1=C([H])C([H])=C(C([H])=C1[H])C(=O)OC([H])([H])C(=O)N(C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])C([H])=C2N(N=NC2=C1[H])C(=O)N1C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C(=C([H])C([H])=C2[H])C(=O)N2C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]N(C(=O)N([H])[C@]1([H])N=C(C2=C([H])C([H])=C([H])C([H])=C2[H])C2=C([H])C([H])=C([H])C([H])=C2N(C1=O)C([H])([H])[H])C1=C([H])C([H])=C([H])C(=C1[H])C(=O)OC([H])([H])[H]
[H]C1=C(ON=C1C(=O)N1C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2C([H])([H])C1([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H]
[H]N(C1=C2SC(=C([H])C2=NC([H])=N1)C1=C([H])C([H])=C(O1)C([H])([H])N([H])C([H])([H])C#N)C1=C([H])C([H])=C(OC([H])([H])C2=C([H])C([H])=C([H])C(F)=C2[H])C(Cl)=C1[H]
CNC(=O)[C@@H](CC1=CC=C(OC)C=C1)NC(=O)C(CC(C)C)CP(O)(=O)CC1=CC(CCC2=CC=CC=C2)=CC=C1
[H]C1=NN(C([H])=C1[H])C([H])([H])C(=O)C([H])([H])OC1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]N1N=NC(=N1)[C@@]1([H])OC2=C([H])C(OC([H])([H])C3=C([H])C(OC([H])([H])C4=NC5=C([H])C([H])=C([H])C([H])=C5C([H])=C4[H])=C([H])C([H])=C3[H])=C([H])C([H])=C2C(=O)C1([H])[H]
CC1=CC=CC(NC(=O)\C=C\C2=CC(O)=CC=C2)=C1
[H]N(OC([H])([H])[H])C(=O)C1=C([H])C(N([H])C2=NC([H])=NN3C([H])=C(C(=O)N([H])C4([H])C([H])([H])C([H])([H])C([H])([H])C4([H])[H])C(=C23)C([H])([H])[H])=C(C([H])=C1[H])C([H])([H])[H]
[H]N1N(C2=NC(F)=C([H])C([H])=C2[H])C([H])([H])C([H])([H])N([H])C1=O
[H]C1=C([H])C([H])=C2N(C(=O)N3C([H])([H])[C@@]([H])(C(=O)C([H])([H])[C@@]3([H])C([H])([H])[H])C([H])([H])[H])C3=C([H])C([H])=C([H])C([H])=C3SC2=C1[H]
[H]C1=C([H])C(N2C([H])([H])C([H])([H])N(C3=NC(=C([H])C(=N3)C([H])([H])[H])C([H])([H])[H])C([H])([H])C2([H])[H])=C(C#N)C(=O)N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]OC1=NC2=C([H])C([H])=C(Cl)C([H])=C2N2N=C(N=C12)C(=O)OC([H])([H])C([H])([H])[H]
[H]N(C(=O)C([H])([H])C([H])([H])C(=O)C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C(=C([H])C([H])=C1F)C([H])([H])C1=NN([H])C(=O)C2=C1N([H])C([H])([H])C([H])([H])C2([H])[H]
[H]C1=C([H])C(=C([H])C([H])=C1OC([H])([H])C([H])([H])N1C2=NC3=C(N2C([H])([H])C([H])([H])C1([H])[H])C(=O)N(C(=O)N3C([H])([H])[H])C([H])([H])[H])C([H])([H])[H]
[H]OC(=O)[C@@]([H])(OC([H])([H])[H])C([H])([H])C1=C2SC([H])=C([H])C2=C(OC([H])([H])C([H])([H])C2=C(OC(=N2)C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])[H])C([H])=C1[H]
COC1=CC=C(C=C1)C(CCC(N)C(O)=O)(C1=CC=CC=C1)C1=CC=CC=C1
[H]C1=C([H])C2=C(O1)C([H])=C([H])C([H])=C2C([H])([H])C(=O)N(C([H])([H])[H])[C@]1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])N1C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]OC1=C([H])C(=O)C(O[H])=C(C1=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]N([H])C1=NC(=C([H])C2=NC(=NN12)C1=C([H])C([H])=C([H])O1)C1=C([H])C(=C([H])C([H])=C1[H])N1C([H])([H])C([H])([H])N(C(=O)OC([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]C1=C([H])C(=C([H])C(=C1[H])S(=O)(=O)C([H])([H])[H])N1C(=O)O[C@]([H])(C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C1([H])[H]
[H]OC1=C([H])C2=C(C([H])=C([H])C(=O)N2C([H])([H])C([H])([H])C([H])([H])N2C([H])([H])C([H])([H])N(C3=C([H])C([H])=C(F)C([H])=C3[H])C([H])([H])C2([H])[H])C([H])=C1[H]
[H]OC(=O)[C@@]([H])(N([H])C(=O)[C@]([H])(C([H])([H])[H])C([H])([H])S[H])C([H])([H])SC([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N1C(=C([H])C2=C([H])C(OC([H])([H])C([H])([H])N3C([H])([H])C([H])([H])C([H])([H])C([H])([H])C3([H])[H])=C([H])C([H])=C12)C(=O)C1=C([H])C2=C(N1[H])C([H])=C(OC([H])([H])[H])C([H])=C2[H]
[H]N(C(=O)C1=NN(C2=C1C([H])([H])C([H])([H])C1=C2N=C(N=C1[H])N([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H])C1([H])C([H])([H])C1([H])[H]
CN1C(C)=CC2=C1C(=NN=C2NCCCN1CCN(CC1)C(=O)C1=CN=CS1)C1=CC=CC(=C1)N(O)=O
[H]N(C(=O)OC([H])([H])C([H])([H])[H])C1=C([H])C([H])=C([H])C(N([H])C(=O)C2=C([H])C([H])=C([H])C([H])=C2Br)=C1[H]
[H]OC1=C(SC(=N1)C1=C([H])C([H])=C(C([H])=C1[H])[N+]([O-])=O)C([H])([H])[H]
[H]OC1=C([H])C2=C(C([H])=C1[H])[C@@]1([H])C([H])([H])C([H])([H])[C@]3(C([H])([H])[H])[C@@]([H])(N([H])S(=O)(=O)C4=C([H])C([H])=C([H])C(=C4[H])[N+]([O-])=O)C([H])([H])C([H])([H])[C@@]3([H])[C@]1([H])C([H])([H])C2([H])[H]
[H]OC1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[C@]([H])(N([H])[H])C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[H])C([H])([H])C1=C([H])C([H])=C(O[H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])N=C(N([H])[H])N([H])[H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])N=C(N([H])[H])N([H])[H])C([H])([H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H])C([H])([H])SSC([H])([H])[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])[H])C([H])([H])C1=C([H])C([H])=C(O[H])C([H])=C1[H])C([H])([H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[H])C([H])([H])C1=C([H])C([H])=C(O[H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])N=C(N([H])[H])N([H])[H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])N=C(N([H])[H])N([H])[H])C([H])([H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H]
[H]N([H])C1=N[C@@]([H])(N([H])C2=C([H])C([H])=C([H])C(F)=C12)C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]OC1=C([H])C(=C([H])C([H])=C1[H])[C@]1([H])N(C(=O)C([H])([H])C([H])([H])C([H])([H])N([H])[H])C([H])([H])C([H])([H])C2=C1N([H])C1=C2C([H])=C(C([H])=C1[H])C([H])([H])[H]
[H]N=C(N([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N([H])C(=O)C1=C([H])C([H])([H])C([H])([H])[C@]1([H])C(=O)N(C1=C([H])C([H])=C([H])C(OC([H])([H])[H])=C1[H])C([H])([H])C([H])([H])[H]
[H]N(\C(SC([H])([H])C1=C([H])SC2=NC([H])([H])C([H])([H])N12)=N\C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C([H])C(=C1[H])C(F)(F)F)C([H])([H])C(=O)N([H])[C@]([H])(C(=O)N([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])N([H])C([H])([H])C1=C([H])C(=C(OC([H])([H])[H])C([H])=C1C([H])([H])[H])C([H])([H])[H]
[H]N1C([H])=C([H])C2=C([H])C([H])=C(C([H])=C12)C1=NN=C(C([H])=C1[H])N1C([H])([H])[C@@]2([H])N(C([H])([H])[H])C([H])([H])[C@]1([H])C2([H])[H]
[H]OC(=O)C1=C([H])C(=C([H])C([H])=C1[H])C1=C(C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C(Cl)C([H])=C1OC([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C1=C([H])C([H])=C2N(C(=NC2=C1[H])[C@]([H])(C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(Cl)C([H])=C1Cl
[H]N=C(N([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@]([H])(N([H])S(=O)(=O)C([H])([H])C([H])([H])C([H])([H])[H])[C@@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C(=O)N([H])[H]
[H]\C(=C1\S\C(=N/C([H])([H])C([H])([H])[H])N(C1=O)C([H])([H])C([H])([H])[H])C1=C(N(C(=C1[H])C([H])([H])[H])C([H])([H])C1=C(F)C([H])=C([H])C([H])=C1F)C([H])([H])[H]
[H]OC(=O)C1=C([H])C(N([H])C2=NC(N([H])C3=C(C([H])=C([H])C([H])=C3[H])C(=O)O[H])=C(F)C([H])=N2)=C([H])C([H])=C1[H]
[H]OC(=O)[C@]([H])(SC1=NC(OC([H])([H])C([H])([H])C2=C([H])SC([H])=C2[H])=C([H])C(OC([H])([H])C([H])([H])C2=C([H])SC([H])=C2[H])=N1)C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]OC(=O)C([H])([H])C([H])([H])N([H])C1=C(C2=C(S1)C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C1=NN=C(SC([H])([H])C(=O)N([H])N([H])C(=O)C2=C([H])C([H])=C([H])C([H])=C2[H])N1N([H])C(=O)C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC1=C([H])C([H])=C(C([H])=C1[H])C1=NN2C(N=C(C([H])=C2C(F)(F)F)C(F)(F)F)=C1C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)[C@@]1([H])OC([H])([H])C([H])([H])C1([H])[H])C([H])([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])N(C1=NS(=O)(=O)C2=C([H])C(F)=C([H])C([H])=C12)C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N1C([H])=NC(=C1[H])C([H])([H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])C2=C([H])C([H])=C(OC([H])([H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]OC([H])([H])[C@@](N([H])[H])(C([H])([H])OP(=O)(O[H])O[H])C([H])([H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]C1=NC([H])=C([H])C(=C1[H])C([H])([H])N1N=C(C2=C([H])C(=C([H])C([H])=C2[H])[N+]([O-])=O)C2=C(C([H])=C([H])C([H])=N2)C1=O
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[H]N([H])C(=O)C1=C(N([H])C2=C(F)C([H])=C(F)C([H])=C2[H])C2=C([H])C(N3C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C3([H])[H])=C(OC([H])([H])C([H])([H])[H])C([H])=C2N=C1[H]
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[H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])OC1=C([H])C([H])=C2C(=C1[H])\C(C(C(=O)OC([H])([H])C([H])([H])[H])=C2C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H])=[N+](/[O-])C([H])([H])[H]
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[H]OC1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])C(=O)N([H])C([H])([H])C([H])([H])N([H])C(=O)C([H])([H])C1=C([H])C([H])=C(N([H])C(=O)C([H])([H])C2=C([H])C([H])=C(N([H])C3=NC([H])=NC4=C3N=C([H])N4[C@]3([H])O[C@]([H])(C([H])([H])O[H])[C@@]([H])(O[H])[C@@]3([H])O[H])C([H])=C2[H])C([H])=C1[H]
[H]N(C(=O)N1C([H])([H])C([H])([H])[C@@]([H])(C2=C([H])C([H])=C([H])C([H])=C2[H])C1([H])[H])C([H])([H])[C@]([H])(C1=C(N([H])C2=C1C([H])=C(S2)C(C(=O)N1[C@@]2([H])C([H])([H])C([H])([H])[C@]1([H])C([H])([H])C2([H])[H])(C([H])([H])[H])C([H])([H])[H])C1=C([H])C(=C([H])C(=C1[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])[H]
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[H]OC(=O)C([H])([H])[C@]([H])(SC1=C([H])C([H])=C([H])C([H])=C1N([H])C(=O)C([H])([H])C([H])([H])[H])C1=C([H])C([H])=C([H])N=C1[H]
[H]N([H])C(=O)C1=C2N([H])C([H])([H])C([H])([H])N([H])C([H])([H])C([H])([H])C([H])([H])C3=C(C4=C(N3C(C([H])=C1[H])=C2[H])C([H])([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C4=O)C([H])([H])[H]
[H]OC1=C([H])C([H])=C(C([H])=C1C([H])([H])[H])S(=O)(=O)N(C1=C(C([H])=C([H])C([H])=C1C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[H]
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[H]N([H])C(=O)[C@@]1([H])N(C([H])([H])[C@]2([H])C([H])([H])N3C4=C(C5=C3C(=C([H])C([H])=C5[H])C2([H])[H])C2=C(C(=O)N([H])C2=O)C2=C4N([H])C3=C2C([H])=C([H])C(F)=C3[H])C([H])([H])C([H])([H])C1([H])[H]
[H]C1=NC(OC2([H])C([H])([H])N(C3=C([H])C([H])=C4C([H])=C([H])C([H])=C([H])C4=N3)C2([H])[H])=C(N=C1[H])N1C([H])([H])C([H])([H])C([H])([H])C(F)(F)C1([H])[H]
[H]OC1=C2N=C([H])N(C2=NC([H])=N1)C([H])([H])C([H])([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C([H])([H])P(=O)(O[H])O[H]
[H]N1C(=O)C([H])([H])S[C@]([H])(C2=C([H])C([H])=C(OC([H])([H])C([H])([H])[H])C([H])=C2[H])C1([H])[H]
[H]C1=C([H])C(=C([H])C([H])=C1Cl)[C@@]1([H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[C@@]1([H])C(=O)N1C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(C(=O)C(\[H])=C(\[H])C1=C([H])N(N=C1C1=C([H])C([H])=C(C([H])=C1[H])[N+]([O-])=O)C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]N([H])[C@@]([H])(C([H])([H])C(=O)N1C([H])([H])C([H])([H])N([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C1=C(F)C([H])=C(F)C(F)=C1[H]
[H]N1C([H])=C(C2=C1C([H])=C([H])C(C#N)=C2[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C([H])C([H])=C([H])C(OC([H])([H])C([H])([H])OC([H])([H])C([H])([H])OC([H])([H])C([H])([H])[H])=C2C#N)C([H])([H])C1([H])[H]
[H]N=C(N([H])[H])C1=C([H])C(=C([H])C([H])=C1[H])C([H])([H])[C@]([H])(N([H])S(=O)(=O)C1=C([H])C2=C([H])C([H])=C([H])C([H])=C2C([H])=C1[H])C(=O)N1C([H])([H])C([H])([H])N(C(=O)OC2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]OC(=O)C([H])([H])N1C(=S)S\C(=C(\[H])C2=C([H])C([H])=C(OC([H])([H])C3=C([H])C([H])=C([H])C([H])=C3[H])C([H])=C2[H])C1=O
[H]C1=C([H])C(=C([H])C([H])=C1C(=O)N(C([H])([H])[H])[C@]1([H])C([H])([H])N(C(=O)N2C([H])([H])C([H])([H])[C@@]([H])(N(C([H])([H])[H])C3([H])C([H])([H])C([H])([H])OC([H])([H])C3([H])[H])C2([H])[H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C(F)(F)F
[H]N([H])C(=O)C1=C([H])N(C2=C([H])C([H])=C3C(=C2[H])C([H])([H])C([H])([H])C3([H])[H])C2=C(C([H])=NC(=N2)N([H])C([H])([H])C([H])([H])C([H])([H])N2C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C2([H])[H])C1=O
[H]OC1(C2=C([H])C([H])=C(Cl)C([H])=C2[H])C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])C1(C([H])([H])[H])C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])S(=O)(=O)C1=C(Cl)C([H])=C([H])C([H])=C1[H]
[H]OC1=C([H])C(C#N)=C([H])C(=C1[H])N1N=NC(=N1)C1=NC([H])=C([H])C([H])=C1[H]
[H]C1=C([H])C(Cl)=C([H])C(=C1[H])C([H])([H])N1C2=NC3=C(N2C([H])([H])C([H])([H])C1([H])[H])C(=O)N(C(=O)N3C([H])([H])[H])C([H])([H])[H]
[H]N([H])C(=O)C1=NN(C2=C1C([H])([H])C([H])([H])N(C2=O)C1=C([H])C([H])=C(C([H])=C1[H])C1(C([H])([H])C([H])([H])N2C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]N1C([H])([H])C([H])([H])C2=C([H])C(Cl)=C([H])C([H])=C2[C@]([H])(C([H])([H])[H])C1([H])[H]
[H]N(\N=C(/[H])[C@@]([H])(N([H])C(=O)OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C(=O)N(C([H])([H])[H])C([H])([H])[H]
[H]O[C@]([H])(C([H])([H])OC1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])N([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C(N([H])C(=O)C([H])([H])C2=C([H])C([H])=C([H])C(OC([H])([H])C3=C([H])C([H])=C([H])C([H])=C3[H])=N2)C([H])=C1[H]
[H]C1=NC2=C([H])C([H])=C(C([H])=C2N=C1[H])C1=C(C(=O)N(N1C([H])([H])[H])C([H])([H])[H])C1=C([H])C(=C([H])C([H])=C1[H])C([H])([H])C([H])([H])[H]
[H]C1=C([H])N2C(=NC(=C2C2=C([H])C(OC3=C([H])C([H])=C([H])C(=C3[H])S(=O)(=O)C(F)(F)F)=C([H])C([H])=C2[H])C([H])(C([H])([H])[H])C([H])([H])[H])C(=C1[H])C(F)(F)F
[H]N([H])C1=C(Cl)C([H])=C(C(=O)N([H])[C@@]2([H])C([H])([H])C3([H])N(C([H])([H])C4=C([H])C([H])=C([H])O4)[C@]([H])(C([H])([H])C3([H])[H])C2([H])[H])C(OC([H])([H])[H])=C1[H]
[H]O[C@@]([H])(C([H])([H])OC1=C([H])C([H])=C([H])C2=C([H])C([H])=C([H])C([H])=C12)C([H])([H])[N+](C([H])([H])[H])(C([H])([H])[H])C([H])([H])C(=O)N([H])C1=C(C([H])=C(C([H])=C1C([H])([H])[H])C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)C1=C(C([H])=C([H])C([H])=C1[H])C([H])([H])[H])C1=C([H])C([H])=C(C2=C([H])C([H])=C([H])C([H])=C12)S(=O)(=O)N([H])C1([H])C([H])([H])C([H])([H])N(C(=O)N2C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]N([H])S(=O)(=O)C1=NN=C(S1)N([H])S(=O)(=O)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F
[H]N1C(=O)N(C(=O)C1(C1=C([H])C([H])=C(Br)C([H])=C1[H])C1=C([H])C([H])=C(Br)C([H])=C1[H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]N1C([H])([H])C([H])([H])C2=C([H])C([H])=C(C([H])=C2C([H])([H])C1([H])[H])S(=O)(=O)N1C([H])([H])C([H])(OC2=C([H])C([H])=C([H])C([H])=C2Cl)C1([H])[H]
[H]O[C@@]([H])(C1=C([H])C([H])=C([H])S1)C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C(C#N)N1C([H])([H])[H]
[H]OC([H])([H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])OC2=C(OC([H])([H])[H])C([H])=C3C(=NC([H])=NC3=C2[H])N([H])C2=NC([H])=C(S2)C([H])([H])N([H])S(=O)(=O)C2=C([H])C([H])=C([H])C(F)=C2[H])C([H])([H])C1([H])[H]
[H]N1C(=NC2=C1N(C(=O)N(C2=O)C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[H])C1=C([H])C(OC([H])([H])C(=O)N2C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C2([H])[H])=NN1C([H])([H])[H]
[H]C1=C(N=C(N1C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)C([H])([H])[H])C1=C([H])C([H])=C(Cl)C([H])=C1[H])C([H])(F)F
[H]OC(=O)C([H])([H])C([H])([H])[C@@]([H])(C([H])([H])[H])[C@@]1([H])C([H])([H])C([H])([H])[C@@]2([H])[C@]3([H])[C@]([H])(O[H])C([H])([H])[C@]4([H])C([H])([H])[C@]([H])(N(C(=O)N([H])C([H])([H])C([H])([H])N(C5=C([H])C([H])=C(C([H])=C5[H])[C@]5([H])C6=C7C(=C([H])C(=O)C([H])([H])C7([H])[H])C([H])([H])C([H])([H])[C@@]6([H])[C@]6([H])C([H])([H])C([H])([H])[C@@](O[H])(C#C[H])[C@@]6(C([H])([H])[H])C5([H])[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])[C@]4(C([H])([H])[H])[C@@]3([H])C([H])([H])[C@]([H])(O[H])[C@]12C([H])([H])[H]
[H]N([H])C1=C([H])C2=C(N=C(S2)C2=C([H])C(N([H])[H])=C([H])C([H])=C2[H])C([H])=C1[H]
[H]N(C(=O)N([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@]([H])(N([H])C(=O)OC([H])([H])C1(C([H])([H])C2=C(F)C([H])=C([H])C([H])=C2F)C([H])([H])C([H])([H])C1([H])[H])C(=O)C(=O)N([H])[C@@]([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H])C([H])([H])[H]
[H]OC([H])([H])[C@]([H])(O[H])C([H])([H])SC1=NC(=C(N1[H])C1=C([H])C([H])=NC(N([H])[C@]([H])(C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])=C1[H])C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]OC(=O)C1=C(N([H])C(=O)N([H])[C@@]1([H])C1=C([H])C([H])=C(OC([H])([H])C([H])([H])OC2=C3C([H])=C([H])C([H])=C([H])C3=NC(=C2[H])C([H])([H])[H])C([H])=C1[H])C([H])([H])[H]
[H]N1C([H])([H])[C@@]([H])(N2C3=C(C([H])=C(OC([H])([H])[H])C([H])=C3[H])C([H])([H])C2([H])[H])C([H])([H])[C@@]1([H])C(=O)N1C([H])([H])SC([H])([H])C1([H])[H]
[H]OC1=NC2=C([H])C([H])=C([H])C(Cl)=C2C(O[H])=C1N=O
[H]N([H])[C@@]([H])(C([H])([H])C(=O)N1C([H])([H])C2=NN=C(N2C(C([H])([H])[H])(C([H])([H])[H])C1([H])[H])C(F)(F)F)C([H])([H])C1=C(F)C([H])=C(F)C(F)=C1[H]
[H]O[C@@]([H])(C([H])([H])N(C1=C([H])C(OC2=C([H])C3=C(C([H])=C2[H])C([H])([H])C([H])([H])C([H])([H])C3([H])[H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C(OC(F)(F)C([H])(F)F)=C1[H])C(F)(F)F
[H]OC(=O)[C@]1([H])[C@]([H])(N(C([H])([H])C(=O)N(C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])[C@@]1([H])C1=C([H])C2=C(OC([H])([H])O2)C([H])=C1[H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]N([C@@]([H])(C1=NC2=C([H])C([H])=C([H])C([H])=C2N1[H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])[C@]1([H])C([H])([H])C(=O)N([H])S1(=O)=O)S(=O)(=O)C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]C1=C([H])C(F)=C(C([H])=C1[H])C1=NC(=NO1)C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]\C(C1=C([H])C([H])=C(C([H])=C1[H])N(C([H])([H])[H])C([H])([H])[H])=C1\C(=O)OC2=C([H])C([H])=C([H])C([H])=C2C1=O
[H]N([H])C1(C([H])([H])C2=C(Cl)C([H])=C([H])C([H])=C2Cl)C([H])([H])C([H])([H])N(C2=NC([H])=NC3=C2C([H])=C([H])N3[H])C([H])([H])C1([H])[H]
[H]C([H])=C(C1=C([H])C2=C(C([H])=C1[H])[C@]([H])(N([H])C(=O)C([H])([H])[C@@]([H])(N([H])S(=O)(=O)C1=C([H])C(=C([H])C([H])=C1[H])C(F)(F)F)C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])N([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C(C([H])=C1[H])N1N=C(C2=C([H])C([H])=C([H])C([H])=C2[H])C2=C(C([H])=C([H])C([H])=C2[H])C1=O)[C@@]1([H])C2=C(C([H])=C(C([H])=C2[H])C([H])([H])N2C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(C1=C2C(=NC1=O)C([H])=C([H])C(=C2Br)C([H])([H])[H])C1=C([H])C([H])=C(OC([H])([H])C([H])([H])[H])C([H])=C1[H]
[H]OC1=C(C([H])=C(\C([H])=C(/[H])C2=C([H])C([H])=C(C([H])=C2[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])=C1C([H])([H])[H])C([H])([H])[H]
[H]SC([H])([H])C([H])([H])C([H])([H])[C@]([H])(N([H])[H])C([H])([H])S[H]
[H]N(C1=NC2=C(N=NN2C2=C1SC([H])=C2[H])S(=O)(=O)C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C1=C(N=C2C([H])=C([H])C(=C([H])N12)C([H])([H])C([H])([H])F)C1=C([H])C([H])=C(C([H])=C1[H])N(C([H])([H])[H])C([H])([H])[H]
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[H]N(C1=C([H])C([H])=C(F)C([H])=C1[H])C1=NC(=NC2=C1C([H])=NN2C([H])([H])[H])N1C([H])([H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])C1([H])[H]
[H]OC1=C([H])C(=C([H])C([H])=C1Cl)C1=C2N=C([H])C([H])=C(N2N=C1C1=C([H])C([H])=NC([H])=C1[H])[C@@]1([H])C([H])([H])[C@@]2([H])N([H])[C@]([H])(C([H])([H])C2([H])[H])C1([H])[H]
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[H]C1=C([H])C(Cl)=C2SC(=O)C([H])([H])N(C(=O)C2=C1[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N([H])C1=NC([H])=NC2=C1C([H])=C([H])C(=C2[H])N1C(=C(C2=C1C([H])([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C2=O)C([H])([H])[H])C([H])([H])[H]
[H]OC(=O)[C@@]1([H])N(C(=O)[C@@]([H])(N([H])[P@](=O)(O[H])C([H])([H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])[H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(C(=O)C([H])([H])C([H])([H])[H])C1=C([H])C([H])=C([H])C(=C1[H])C1=NN=C(SC([H])([H])C(=O)N([H])C([H])([H])C2=C([H])C([H])=C([H])O2)N1C([H])([H])[H]
[H]OC(=O)C([H])([H])C([H])([H])[C@]([H])(N([H])C(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C(OC([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])=C1[H]
[H]ON([H])C(=O)C([H])([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@@]([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]N(C(=O)OC1=C([H])C([H])=C2N(C([H])([H])[H])[C@@]3([H])N(C([H])([H])[H])C([H])([H])C([H])([H])[C@]3(C2=C1[H])C([H])([H])[H])C1=C([H])C(Cl)=C([H])C([H])=C1[H]
[H]N(C(=O)C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H])C([H])([H])C1=NC2=C([H])C([H])=C([H])C([H])=C2C(=O)N1C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C1=C([H])C([H])=C(C2=NOC(=C2C(=O)N(C2=C([H])C([H])=C(Cl)C([H])=C2[H])C([H])([H])[H])C([H])([H])[H])C(Cl)=C1[H]
[H]OC(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)C([H])([H])N([H])C(=O)C([H])([H])N([H])C(=O)[C@@]([H])(N([H])[H])C([H])([H])C1=C([H])C([H])=C(O[H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])N=C(N([H])[H])N([H])[H])C([H])([H])C([H])([H])C([H])([H])N=C(N([H])[H])N([H])[H])[C@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])[H]
[H]C1=C(OC(=N1)C(=O)[C@@]1([H])C([H])([H])C2=C(C([H])=C(C([H])=C2[H])C2=C([H])C([H])=C([H])C([H])=C2[H])C1([H])[H])C1=NC([H])=C([H])C([H])=C1[H]
[H]OC1=C2O[C@]3([H])C4=C(C5=C(N4[H])C([H])=C([H])C([H])=C5N=C=S)C([H])([H])[C@]4(O[H])[C@@]5([H])N(C([H])([H])C6([H])C([H])([H])C6([H])[H])C([H])([H])C([H])([H])[C@@]34C2=C(C([H])=C1[H])C5([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C([H])C([H])=C1[H])C(=C(\[H])C1=C([H])C([H])=C([H])C2=C([H])C([H])=C([H])C([H])=C12)\C(=O)OC([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C1=NC(=C([H])C([H])=C1[H])N(C(=O)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C(OC([H])([H])[H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]OC(=O)C([H])([H])[C@@]([H])(C1=C([H])C(Cl)=C([H])C(Cl)=C1[H])C([H])([H])C(=O)N([H])N([H])C(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])C1=C([H])C(=C([H])C([H])=N1)C([H])([H])[H]
[H]C1=C(N(C(=C1[H])C([H])([H])C(=O)N(C1=C([H])C([H])=C(C(=C1C([H])([H])[H])C([H])([H])OC1=C2N=C(C([H])=C([H])C2=C([H])C([H])=C1[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C(=O)C1=C([H])N=C(Cl)C([H])=C1[H]
[H]N1C(=NC2=C1C([H])=C(Cl)C(F)=C2[H])N(C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H])[C@]1([H])C([H])([H])C([H])([H])[C@]2(C3=C([H])C([H])=C([H])C(C#N)=C3[H])C([H])([H])[C@]2([H])C1([H])[H]
[H]N1C(=O)[C@@]2([H])N(C(=O)[C@]([H])(N(C(=O)[C@@]3([H])N(C(=O)[C@]4([H])N(C(=O)[C@@]([H])(N([H])C(=O)[C@@]1([H])C([H])([H])C1=C([H])C([H])=C(OC([H])([H])C([H])([H])[H])C([H])=C1[H])[C@@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C4([H])[H])C([H])([H])C([H])([H])C([H])([H])C3([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C2([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])OC1=C([H])C(=O)N(C([H])=C1[H])C1=C([H])C([H])=C(OC([H])([H])C([H])([H])N2C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])C([H])=C1[H]
[H]O[C@@](C1=C([H])C([H])=C([H])C([H])=C1[H])(C1=C([H])C(Cl)=C(C([H])=C1[H])C1=C2N(C([H])=C([H])N=C2N([H])[H])C(=N1)C1([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])[H]
[H]N(C1=C2N([H])C([H])=C(C2=C(C([H])=N1)C(=O)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1OC([H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)[C@@]([H])(N1C([H])=C(C(=C([H])C1=O)S(=O)(=O)C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C(C([H])=N1)C([H])([H])[H]
[H]OC(=O)C([H])([H])[C@@]1(O[H])C2=C(O[C@]([H])(C([H])([H])[H])C1([H])[H])C([H])=C(F)C(C#N)=C2[H]
[H]N([H])[C@]([H])(C(=O)N1[C@]([H])(C#N)C([H])([H])C([H])([H])[C@]1([H])C([H])([H])[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[C@]1([H])N(C(=O)O[C@@]2([H])C([H])([H])[N@]3C([H])([H])C([H])([H])[C@]2([H])C([H])([H])C3([H])[H])C([H])([H])C([H])([H])C2=C1C([H])=C([H])C([H])=C2[H]
[H]N(C(=O)C1=C([H])C2=C([H])C([H])=C([H])C([H])=C2C([H])=C1[H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=NC([H])=C2[H])C([H])([H])C1([H])[H]
[H]OC1=C([H])C2=C(C([H])=C1[H])[C@]13C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])C#N)[C@]([H])(C2([H])[H])[C@]1([H])C([H])([H])C([H])([H])C([H])([H])C3([H])[H]
[H]N(C(=O)N1C([H])([H])C([H])([H])N(C([H])([H])[C@@]2([H])C([H])([H])N(C([H])([H])C([H])([H])C2([H])[H])C2([H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C(Cl)C(Cl)=C1[H]
[H]N1C(=O)N([H])\C(=C(\[H])C2=C([H])C(OC([H])([H])C3=C([H])C([H])=C(Cl)C(Cl)=C3[H])=C([H])C([H])=C2[H])C1=O