[H]N(C1=NC2=C(S1)C([H])([H])C([H])([H])OC1=C2C([H])=C(F)C([H])=C1[H])C([H])([H])C1([H])C([H])([H])C([H])([H])N(C(=O)C([H])([H])OC([H])([H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N(C1=NC2=C(C([H])=C(N2[H])C2=C([H])C([H])=C(F)C([H])=C2[H])C2=C1N=C([H])N2C([H])([H])[H])C([H])([H])[H]
[H]O[C@@]([H])(C(\[H])=C(/[H])[C@@]1([H])[C@]([H])(O[H])C([H])([H])[C@]([H])(O[H])[C@]1([H])C([H])([H])C(\[H])=C(/[H])C([H])([H])C([H])([H])C([H])([H])C1=NN=NN1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]N1C([H])([H])C([H])([H])N(C2=C3OC([H])=C([H])C3=C([H])C([H])=C2[N+]([O-])=O)C([H])([H])C1([H])[H]
CNC1=NC(C)=C(S1)C1=C(O)C=NC(NC2=CC=CC(=C2)S(N)(=O)=O)=N1
[H]OC(=O)[C@]([H])(OC1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C(SC2=C1C([H])=C([H])C([H])=C2[H])C([H])([H])C1=NC([H])=C([H])S1)C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N1C(=NC(=C1C1=C(OC([H])([H])C([H])([H])C([H])([H])[H])C([H])=C(OC([H])([H])C([H])([H])C([H])([H])[H])C([H])=C1[H])C1=C([H])C([H])=NC([H])=C1[H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]N=C(N([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NO[C@@]([H])(C([H])([H])C(=O)N(C([H])([H])[H])C([H])([H])[C@]([H])(N([H])C(=O)OC([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C(=O)OC([H])([H])[H])C1([H])[H]
[H]N([H])C1=C([H])C(=NC(OC([H])([H])C([H])([H])[H])=C1C#N)N([H])C(=O)C([H])([H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]N(C(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C(=O)N([H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=NC3=C(N([H])C4=C2C([H])=C([H])C([H])=C4[H])C([H])=C([H])C(Cl)=C3[H])C([H])([H])C1([H])[H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=NC3=C(N([H])C4=C2C([H])=C([H])C([H])=C4[H])C([H])=C([H])C(Cl)=C3[H])C([H])([H])C1([H])[H]
[H]O[C@]1([H])C([H])([H])C2=C([H])C([H])([H])[C@@]3([H])[C@@]4([H])C([H])([H])C([H])([H])[C@@]([H])(C5=C([H])C([H])=NO5)[C@@]4(C([H])([H])[H])C([H])([H])C([H])([H])[C@]3([H])[C@@]2(C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N([H])C1=NC(=NC2=NC(=NN12)C1=C([H])C([H])=C([H])O1)N1C([H])([H])[C@@]2([H])N(C([H])([H])C([H])([H])C2([H])[H])C([H])([H])[C@]1([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OP(=O)(O[H])C([H])([H])C([H])([H])C([H])([H])N([H])C([H])([H])C1=C([H])C(Cl)=C(OC([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C(Cl)=C1[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])[C@]1([H])N(N=C(C2=C([H])C(F)=C([H])C([H])=C2F)C1([H])[H])C(=O)N(C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])C(=C([H])C([H])=C1C(=O)C([H])([H])[H])C([H])([H])C(=O)N1C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])C([H])(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H]
[H]OC(=O)C([H])([H])C([H])([H])C(\[H])=C(\[H])C([H])([H])[C@]1([H])C([H])([H])O[C@@]([H])(O[C@]1([H])C1=C(O[H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])OC1=C([H])C([H])=C([H])C(=C1[H])C(=C(\[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C(=O)O[H])\C1=C([H])N=C([H])C([H])=C1[H]
[H]O[C@@]([H])(C([H])([H])OC1=C([H])C([H])=C([H])C([H])=C1[N+]([O-])=O)C([H])([H])N1C([H])([H])C([H])([H])N(C2=C([H])C([H])=C(OC([H])([H])[H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]C1=C([H])C(=C([H])C(=C1[H])C1=NN=C2C([H])=C([H])C(SC3=C([H])C([H])=C(F)C([H])=C3F)=C([H])N12)C(=O)OC([H])([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])[C@@]1([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C(C([H])=C2[H])C2=C([H])C([H])=C([H])C([H])=C2C(F)(F)F)C([H])([H])C([H])([H])C1([H])[H]
[H]C1=NC([H])=C([H])C(=C1[H])N1C([H])([H])C2=C(C([H])=C([H])C([H])=C2Cl)C([H])([H])C1([H])[H]
[H]OC(=O)[C@]1([H])N([H])C(=O)[C@@]([H])(N([H])C(=O)C([H])([H])N([H])C(=O)[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])[H])C([H])([H])C2=C([H])C([H])=C(OC([H])([H])[H])C([H])=C2[H])C(SSC1(C([H])([H])[H])C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)N([H])[C@@]([H])(C(=O)N(C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C(=O)OC([H])([H])C([H])([H])[H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]N(C1=C(C([H])=C(C([H])=C1[H])S(=O)(=O)N([H])C(=O)C1=C([H])C([H])=C(C([H])=C1[H])N1C([H])([H])C([H])([H])C(OC([H])([H])[H])(C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2F)C([H])([H])C1([H])[H])[N+]([O-])=O)[C@@]([H])(C([H])([H])SC1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H]
[H]C1=C2N(C(=N1)C1=C(F)C([H])=C(F)C([H])=C1[H])C([H])([H])C([H])([H])N(C(=O)C1=C([H])C3=C(C([H])=C1Cl)N(C([H])=C3C(=O)C(=O)N(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C2([H])[H]
[H]OC(=O)C1=C(OC2=NC(OC3=C([H])C([H])=C([H])C(=C3[H])C(=N[H])N([H])[H])=C(F)C(N([H])[C@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])C3=C([H])C([H])=C([H])C([H])=C3[H])=C2F)C([H])=C([H])C(O[H])=C1[H]
[H]N(C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])N=C2C([H])=C([H])C([H])=C(C3=C([H])C([H])=NC([H])=C3[H])C2=C1[H])S(=O)(=O)C([H])([H])[H]
[H]N1C(=NC2=C1C([H])([H])N(C(=O)C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C2([H])[H])C1=C([H])C2=C([H])C([H])=C([H])C([H])=C2N([H])C1=O
[H]C1=C([H])C([H])=C(C2=NN=C3SC(=NN23)C2=C([H])C([H])=C(C([H])=C2[H])N(C([H])([H])[H])C([H])([H])[H])C(OC([H])([H])[H])=C1[H]
[H]C1=NC2=C(C([H])=N1)C(=O)C([H])([H])[C@]([H])(C([H])([H])N1C([H])([H])C([H])([H])C([H])(C3=NOC4=C3C([H])=C([H])C(F)=C4[H])C([H])([H])C1([H])[H])C2([H])[H]
[H]OC([H])([H])C([H])([H])N([H])C(=O)C1=C([H])C([H])=C(C([H])=C1[H])C1=C2C([H])=C([H])C([H])=C([H])C2=C(N=N1)N([H])C1=C([H])C([H])=C(OC(F)(F)Cl)C([H])=C1[H]
[H]N([H])[C@@]([H])(C([H])([H])C(=O)N1C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C1=C(F)C([H])=C(F)C(F)=C1[H]
[H]O[C@@]1([H])C([H])([H])N2C3=C([H])C([H])=C([H])C([H])=C3C3=C2C2=C(C4=C(C([H])=C([H])C([H])=C4[H])N2C1([H])[H])C1=C3C([H])([H])N([H])C1=O
[H]N([H])C1=C([H])C2=C(OC(=N2)C(=O)[C@]([H])(N([H])C(=O)C([H])([H])N2C(=O)C(N([H])[H])=C([H])N=C2C2=C([H])C([H])=C(F)C([H])=C2[H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])=C1[H]
[H]ON([H])C(=O)[C@]([H])(N([H])S(=O)(=O)C1=C([H])C([H])=C(C(F)=C1[H])C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]C([H])=C([H])C([H])([H])N1C([H])([H])C([H])=C(C2=C([H])C3=C(C([H])=C([H])C([H])=C3[H])C([H])([H])C3=C2C([H])=C([H])C([H])=C3[H])C([H])([H])C1([H])[H]
[H]C1=C(C(=O)C2=C([H])C([H])=C(C([H])=C2[H])C([H])([H])N2C(=NC3=C2C([H])=C([H])N=C3[H])C([H])([H])[H])C2=C(C([H])=C([H])C([H])=C2N1C(=O)N(C([H])([H])[H])C([H])([H])[H])C(=O)OC([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N1C([H])([H])[C@@]([H])(N2C([H])([H])C([H])([H])N(C3=NC([H])=C(Cl)C([H])=C3[H])C([H])([H])C2([H])[H])C([H])([H])[C@@]1([H])C(=O)N1C([H])([H])SC([H])([H])C1([H])[H]
[H]C1=C([H])C(OC([H])([H])[H])=C2N=C(N(C2=C1Cl)C([H])([H])C([H])([H])OC([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]OC(=O)C([H])([H])C1=NN(C(=O)C2=C1C([H])=C([H])C([H])=C2[H])C([H])([H])C(\S[H])=N\C1=C([H])C(=C([H])C([H])=C1Br)C(F)(F)F
[H]N1C(=O)C2=C(N=C1C1=C(Cl)C([H])=C([H])C([H])=C1[H])C1=C(OC([H])([H])[H])C([H])=C([H])C([H])=C1O2
[H]OC(=O)C1=C([H])C2=C(C([H])=C1[H])C(=C(S2)C([H])([H])N1C([H])=NC([H])=C1[H])C([H])([H])[H]
[H]OC1=C([H])C([H])=C([H])C(=C1[H])C([H])([H])C(=O)N([H])\N=C1/C(=O)N([H])C2=C([H])C([H])=C([H])C([H])=C12
[H]OC(=O)C([H])([H])C([H])([H])[C@]([H])(N([H])C(=O)OC([H])([H])C1([H])C2=C(C([H])=C([H])C([H])=C2[H])C2=C1C([H])=C([H])C([H])=C2[H])C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])(C(=O)O[H])C(=O)O[H]
[H]N(C(=O)C([H])([H])[H])C([H])([H])C([H])([H])C1=C2N(C3=C([H])C([H])=C(OC([H])([H])C([H])([H])[H])C([H])=C13)C([H])([H])C([H])([H])C([H])([H])C1=C2C([H])=C([H])C([H])=C1[H]
[H]N(C1=NN2C([H])=C([H])C([H])=C(C2=N1)C1=C(OC([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C2C(=C1[H])C([H])([H])C([H])([H])N([H])C([H])([H])C2([H])[H]
[H]N(C1=NC(=C([H])C([H])=N1)C1=C(N=C2N1[C@]([H])(C([H])([H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])C([H])([H])C2([H])[H])C1=C([H])C([H])=C(F)C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]N([H])C1=NC2=C(C([H])=C(S2)C(=O)N([H])C([H])([H])C([H])([H])[H])C(=N1)C1=C([H])C(OC([H])([H])C([H])([H])N([H])C2([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])=C(Cl)C([H])=C1Cl
[H]OC(=O)C([H])([H])C1=NN(C(=O)C2=C([H])C([H])=C([H])C([H])=C12)C([H])([H])C1=NC2=C(S1)C([H])=C(Cl)C([H])=C2[H]
[H]N(C(=O)C1=C([H])SC2=C([H])C(OC3=C([H])C([H])=NC4=C3SC(=C4[H])C3=NC([H])([H])C([H])([H])N3C([H])([H])[H])=C([H])C([H])=C12)C([H])([H])[H]
[H]N1C2=NN(C([H])=C2C(=NC2=C1C([H])=C(F)C([H])=C2[H])N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H])C([H])([H])[H]
[H]N1N=NC(=N1)C1=C([H])C([H])=C(OC([H])([H])C([H])([H])C([H])([H])C([H])([H])OC2=C([H])C(=C([H])C([H])=C2OC([H])([H])[H])C2=NN(C(=O)C2(C([H])([H])[H])C([H])([H])[H])C2([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])=C1[H]
[H]O[C@]([H])(C([H])([H])N([H])[C@]1(C2=C([H])C(=C([H])C([H])=C2[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C2=C(N=C(N=C2[H])C([H])([H])[H])C([H])([H])C1([H])[H])[C@@]([H])(N([H])C(=O)C([H])([H])[H])C([H])([H])C1=C([H])C(F)=C([H])C(F)=C1[H]
[H]C1=C([H])C([H])=C2C(=C1[H])C([H])([H])C([H])([H])[C@@]([H])(N(C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[H])C2([H])[H]
[H]OC(=O)C1=C(O[H])C(=C(OC([H])([H])[H])C([H])=C1C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C(\[H])=C(\C([H])([H])[H])C([H])([H])C([H])([H])C([H])=C(C([H])([H])[H])C([H])([H])[H]
[H]C#CC1=C(N([H])S(=O)(=O)C([H])([H])[H])C(F)=C([H])C(=C1[H])C([H])([H])N([H])C(=S)C([H])([H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)C1=C([H])C2=C([H])C(N([H])C(=O)C([H])([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])=C([H])C([H])=C2N1C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]\C(=N/N(C(=O)C1=C([H])C([H])=C([H])C(=C1[H])[N+]([O-])=O)C([H])([H])[H])C1=C2C([H])=C(C#N)C([H])=C([H])N2N=C1[H]
[H]O\C(OC([H])([H])C([H])([H])[H])=C1\C(=NC(=C(C(=O)OC([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])[C@@]1([H])C1=C([H])C(=C([H])C([H])=C1[H])N1C([H])=NC([H])=C1[H])C([H])([H])[H])C([H])([H])[H]
[H]N(C([H])([H])C#CC1=C([H])C([H])=C([H])C([H])=C1[H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]C1=C([H])C(OC([H])([H])C([H])([H])N2C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])=NN1C1=C([H])C([H])=C(Cl)C(Cl)=C1[H]
[H]N(C(=O)C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C([H])C([H])=C(Cl)C([H])=C2[H])C([H])([H])C1([H])[H]
[H]C1=NN(C2=C1C([H])([H])C([H])([H])C([H])([H])C1=C(SC(=C21)C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C1=C([H])C(OC([H])([H])[H])=C2C(=C1[H])[C@]([H])(OC([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])(C([H])([H])C1([H])[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C([H])([H])C2([H])[H]
[H]N([C@]1([H])C(=O)N(C([H])([H])C1([H])[H])[C@]([H])(C(=O)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C([H])([H])[H])S(=O)(=O)C1=C([H])C2=C(S1)C([H])=C([H])C(Cl)=N2
[H]C1=C(C([H])=C2C(=C1[H])N(C(=S)OC2(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])[H])C1=C([H])C(F)=C([H])C(C#N)=C1[H]
[H]OC(=O)[C@]([H])(C([H])([H])C1=C([H])C(C(=O)N([H])C([H])([H])C([H])([H])C2=C([H])C([H])=C(C([H])=C2[H])C(F)(F)F)=C(OC([H])([H])[H])C([H])=C1[H])C([H])([H])C([H])([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C(Cl)C([H])=C1[H])C1=C([H])C([H])=C2C([H])=C(C([H])([H])N(C(=O)OC([H])([H])C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C2=C1[H]
[H]O[C@]1([H])C([H])([H])N(C([H])([H])C([H])([H])[C@@]11C(=O)N(C2=C([H])C([H])=C(O[C@]([H])(C([H])([H])[H])C(F)(F)F)C([H])=C2[H])C([H])([H])C1([H])[H])S(=O)(=O)C1=C(Cl)C([H])=C([H])C([H])=C1[H]
[H]N1C([H])=C([H])C2=C1C([H])=C([H])C(=C2[H])S(=O)(=O)C1=C([H])C([H])=C2N(C3=C(C2=C1[H])[C@@]1([H])N(C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])[C@]([H])(C([H])([H])C1([H])[H])C3([H])[H])C([H])([H])[H]
[H]ON([H])C(=O)[C@]1([H])N(C([H])([H])C([H])([H])SC1(C([H])([H])[H])C([H])([H])[H])S(=O)(=O)C1=C([H])C([H])=C(OC([H])([H])C#CC([H])([H])N([H])C(=O)OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])=C1[H]
CCSc1nnc2N(CCCn12)C(=O)CN1CCOCC1
[H]OC(=O)C1=C(C2=C([H])C([H])=C(OC([H])([H])[H])C([H])=C2[H])C2=C([H])C(OC([H])([H])[H])=C([H])C([H])=C2O[C@@]1([H])C1=C([H])C([H])=C2OC([H])([H])OC2=C1[H]
[H]ON(C(=O)C(\[H])=C(/[H])SC1=NC2=C([H])C([H])=C([H])C([H])=C2S1)C([H])([H])[H]
[H]N(C(=O)C([H])([H])[C@@]1([H])C2=C([H])C([H])=C(Cl)C([H])=C2N([H])C(=O)[C@]1([H])[N+]([O-])=O)C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N1C2=C([H])C([H])=C(C([H])=C2C(=C([H])C1(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C1=C(Br)C([H])=C(S1)C#N
[H]OC1=C(N([H])C2=C(N([H])[C@@]([H])(C3=C([H])C([H])=C(O3)C([H])([H])[H])C(F)(F)C([H])=C([H])[H])C(=O)C2=O)C([H])=C([H])C([H])=C1C(=O)N(C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[C@]1([H])[N@]2C([H])([H])C([H])([H])[C@]([H])(C([H])([H])C2([H])[H])[C@@]1([H])OC([H])([H])C1=C([H])C(=C([H])C(=C1[H])C(F)(F)F)C(F)(F)F
[H]N1C(=O)OC2=C(C([H])=C([H])C([H])=C12)C([H])([H])N1C([H])([H])C([H])([H])N(C([H])([H])[C@]2([H])C([H])([H])C3=C(N([H])C4=C3C([H])=C(F)C([H])=C4[H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]N1C2=C([H])C(=C(C([H])=C2N=C(C2=C([H])C([H])=C([H])C(=C2[H])C2=C([H])N=NC([H])=C2[H])C([H])([H])C1=O)C([H])([H])[H])C(F)(F)F
[H]C1=C(OC([H])([H])[H])N=C(O1)C(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC(=O)C([H])([H])[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=O)N([H])C1=C([H])C([H])=C([H])C(Cl)=C1Cl)C(=O)N([H])[C@@]([H])(C(=O)N([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C1=C([H])C(OC([H])([H])[H])=C(Cl)C([H])=C1Cl)C1=C(C#N)C([H])=NC2=C1C([H])=C(OC([H])([H])[H])C(=C2[H])C1=C([H])C([H])=C(O1)C([H])([H])N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N1C([H])([H])C([H])([H])C([H])([H])[C@@]([H])(C([H])([H])N2C(=O)C3=C(N=C2C2=C([H])C([H])=C([H])C([H])=C2C([H])([H])[H])C([H])=C([H])C(OC2=C([H])C([H])=C(F)C([H])=C2[H])=C3[H])C1([H])[H]
[H]O[C@]1(C2=C([H])C(=C([H])C([H])=N2)C([H])([H])[H])C([H])([H])[C@@]2([H])N([C@@]([H])(C3=C([H])C([H])=C([H])C([H])=C3Cl)C3=C([H])C([H])=C(C([H])=C3Cl)C([H])([H])[H])[C@]([H])(C([H])([H])C2([H])[H])C1([H])[H]
[H]N=C(N([H])[H])N1C([H])([H])C([H])([H])C([H])([H])[C@@]([H])(C([H])([H])[C@]([H])(N([H])C(=O)[C@@]2([H])N3C(=O)C([H])([H])N(C(=O)C([H])([H])C([H])([H])C4=C([H])C([H])=C([H])C([H])=C4[H])C([H])([H])[C@]3([H])C([H])([H])C2([H])[H])C(=O)C2=NC3=C(S2)C([H])=C([H])C([H])=C3[H])C1([H])[H]
[H]N(C(=O)OC1=C([H])C([H])=C([H])C(=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C(=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N([H])S(=O)(=O)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])OC(=O)C([H])([H])[N+]1=C(C([H])=C(C([H])=C1C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H]
[H]OC(=O)C([H])([H])C([H])([H])C([H])([H])[C@]([H])(O[H])[C@]([H])(SC([H])([H])[C@]([H])(N([H])[H])C(=O)O[H])C(\[H])=C(/[H])\C(\[H])=C(/[H])\C(\[H])=C(\[H])C([H])([H])C(\[H])=C(\[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]N=C(N([H])C1=C([H])C(=C([H])C([H])=C1[H])C([H])([H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C([H])([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C(OC2=C([H])C([H])=C([H])C([H])=C2[H])C([H])=C1[H])C1=C([H])C([H])=C(OC([H])([H])C([H])([H])N2C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C(OC([H])([H])[H])=C1[H]
[H]OC1=C([H])C([H])=C(C([H])=C1[H])[C@@]1([H])SC2=C([H])C(O[H])=C([H])C([H])=C2O[C@@]1([H])C1=C([H])C([H])=C(OC([H])([H])C([H])([H])C([H])([H])N2C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])=C1[H]
[H]OC1=C([H])C2=C(N([H])C(=C2[H])C2=NC(=C([H])N=C2[H])C2=C([H])C([H])=C(C([H])=C2[H])S(=O)(=O)C([H])([H])[H])C([H])=C1[H]
[H]N([C@@]1([H])C([H])([H])C([H])([H])[C@@]([H])(N2C([H])([H])C([H])([H])N(C3=C(OC([H])(C([H])([H])[H])C([H])([H])[H])C([H])=C([H])C([H])=C3[H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H])S(=O)(=O)C1=C(OC([H])([H])[H])C([H])=C([H])C(Br)=C1[H]
[H]N(C1=NC([H])=C([H])C(=N1)C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)N1C([H])([H])C([H])([H])N([H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N1C([H])=C(N=C1C1=C([H])C([H])=C([H])N=C1[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N1C(=O)C2=C(C1=O)C1=C(C([H])=C([H])C3=C1N(C([H])=C3[H])C([H])([H])[H])C1=C2C2=C(C([H])=C(OC([H])([H])[H])C([H])=C2[H])N1C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H]
[H]OC([H])([H])[P@@](=O)(O[H])[C@@]([H])(C([H])([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H])P(=O)(O[H])O[H]
[H]O[C@@]1([H])[C@@]([H])(O[C@]([H])(C([H])([H])[H])[C@@]1([H])O[H])N1C([H])=C(C2=C1N=C([H])N=C2N([H])C1=C([H])C([H])=C(C#N)C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C1=C([H])C(Cl)=C(C([H])=C1Cl)C([H])([H])N(C1=C([H])C(Cl)=C(C#N)C([H])=C1[H])[C@]1([H])C([H])([H])N(C(=O)C1([H])[H])C([H])([H])C([H])([H])[H]
[H]N([H])[C@@]([H])(C(=O)N1C([H])([H])C([H])([H])N(C2=NC([H])=NC3=C2[C@@]([H])(OC3([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]N(C1=NC2=C([H])C(=C([H])C([H])=C2O1)S(=O)(=O)C([H])([H])C([H])([H])[H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C(OC([H])([H])[H])C(OC([H])([H])C([H])([H])[H])=C2[H])C([H])([H])C1([H])[H]
[H]N(C([H])([H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C2=C(C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H])S(=O)(=O)C1=C([H])C2=C([H])C([H])=C([H])C([H])=C2C([H])=C1[H]
[H]OC(=O)C([H])([H])C1=C([H])C([H])=C([H])N1C1=C([H])C2=C(OC([H])([H])C([H])([H])O2)C([H])=C1[H]
[H]OC(=O)[C@]1([H])N(C(=O)C2=C([H])C([H])=C(C([H])=C2[H])C2=NC([H])([H])C([H])([H])N2C([H])([H])[H])C([H])([H])C([H])([H])N(C1([H])[H])S(=O)(=O)C1=C([H])C2=C(N1[H])C([H])=C([H])C(Cl)=C2[H]
[H]N(C1=NC2=C([H])C([H])=NN2C(N(C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[H])=C1C([H])(C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1Cl
[H]OC1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[C@]([H])(N([H])C([H])([H])[H])C(=O)N([H])C([H])([H])C(=O)N([H])C([H])([H])C(=O)N([H])[C@@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])N=C(N([H])[H])N([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N=C(N([H])[H])N([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C1=C([H])C2=C3C(=C1[H])C([H])([H])C1=C([H])C([H])=C4C(=C31)[C@@](N(C([H])([H])[H])C([H])([H])C4([H])[H])(C([H])([H])[H])C2([H])[H]
[H]O[C@]([H])(C([H])([H])N([H])C1(C2=C([H])C([H])=C([H])C(=C2[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H])[C@@]1([H])N([H])C(=O)C2=C([H])C(OC([H])([H])C([H])([H])C([H])([H])C([H])([H])OC3=C([H])C([H])=C([H])C(=C3[H])C1([H])[H])=NC(=C2[H])C([H])([H])OC([H])([H])[H]
[H]OC(=O)C1=C2N(C(=NC2=C([H])C([H])=C1[H])C([H])([H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C(C([H])=C([H])C([H])=C1[H])C1=NOC(O[H])=N1
ClC1=CC(Cl)=C(C=C1)C1=CSC(NN=C2CCCCC2)=N1
[H]C1=C([H])C([H])=C(C([H])=C1[H])N1C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])[C@]([H])(C1=NN=NN1C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]OC(=O)C([H])([H])C1=NN(C(=O)C2=C1C([H])=C([H])C([H])=C2[H])C([H])([H])C1=NC2=C(S1)C([H])=C([H])C(=C2[H])C(F)(F)F
[H]N(C(=O)C#CC([H])([H])OC([H])([H])[H])C1=C([H])C([H])=C2N=C([H])C(C#N)=C(N([H])C3=C([H])C(Br)=C([H])C([H])=C3[H])C2=C1[H]
[H]N=C1N([H])\C(=C(\[H])C2=C([H])N([H])C3=C2C([H])=C(Br)C([H])=C3[H])C(=O)N1C([H])([H])[H]
[H]O[C@@]1([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2C2=C([H])C([H])=C(N3C(=O)C4=C(C(=NN4C4=C([H])C5=C(ON=C5N([H])[H])C([H])=C4[H])C([H])([H])[H])C([H])([H])C3([H])[H])C(F)=C2[H])C([H])([H])C1([H])[H]
[H]OC(=O)C1=C(Cl)C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C(O1)C(\[H])=C1/SC(=O)N(C1=O)C([H])([H])C(=O)OC([H])([H])C([H])([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C(C([H])=C1[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C1=C([H])C2=C(SC(=N2)C([H])([H])[H])C([H])=C1[H]
[H]N([H])C1=C([H])C2=C(N=C(SC([H])([H])C3=C([H])C(F)=C([H])C([H])=C3[H])S2)C([H])=C1[H]
[H]N(C(=O)C(\[H])=C(/[H])C1=C([H])N(C2=C([H])C([H])=C([H])C(OC3=C([H])C(Cl)=C(Cl)C([H])=C3[H])=C12)C([H])([H])[H])S(=O)(=O)C1=C(F)C([H])=C(F)C(F)=C1[H]
[H]OC(=O)C([H])([H])[C@]([H])(N1C([H])([H])C([H])([H])C([H])(C(=O)N2C([H])([H])C([H])([H])C3(C([H])([H])N(C4=C([H])C([H])=NC([H])=C4[H])C([H])([H])C3([H])[H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H])C([H])([H])[H]
[H]N([H])[C@@]([H])(C([H])([H])C(=O)N1C([H])([H])C2=C(ON=C2C([H])([H])C1([H])[H])C(F)(F)F)C([H])([H])C1=C([H])C(F)=C([H])C([H])=C1F
[H]OC1=C(O[H])C([H])=C(C([H])=C1[H])[C@@]([H])(O[H])C([H])([H])N([H])C([H])([H])[H]
CN(CCCCCCCCCCCN)CCCCCCCCCCCNC(=O)C1=NN(C(=C1C)C1=CC=C(Cl)C=C1)C1=C(Cl)C=C(Cl)C=C1
[H]C1=C(N(C(=C1C([H])([H])C(=O)OC([H])([H])C([H])([H])O[N+]([O-])=O)C([H])([H])[H])C1=C([H])C([H])=C(F)C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)C([H])([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C([H])([H])N1C(=O)N2C([H])([H])C3=C([H])C([H])=C([H])C([H])=C3C([H])([H])[C@@]2([H])C1=O
[H]N([H])C1=C2C([H])=C(SC2=C(C([H])=N1)C(=O)N([H])C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]N([H])C(=O)C1=C([H])C2=C(N([H])C([H])=C2C([H])([H])C([H])([H])C([H])([H])C([H])([H])N2C([H])([H])C([H])([H])C([H])(C3=C([H])C([H])=C([H])C([H])=C3[H])C([H])([H])C2([H])[H])C([H])=C1[H]
[H]N([H])C1=C(N([H])C(=O)C2=C([H])C([H])=C(N=C2[H])N2C([H])([H])C([H])([H])N(C(=O)OC([H])([H])C3=C([H])C([H])=C([H])C([H])=C3[H])[C@]([H])(C2([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])S(=O)(=O)C1=C([H])C([H])=C([H])C([H])=C1C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1C(=O)N(N=C1C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1C(F)(F)F
[H]N([H])C([H])([H])C([H])([H])N(C1=C([H])C(=C([H])C([H])=C1[H])C1=NN2C(N=C([H])C([H])=C2C2=C([H])C(OC([H])([H])C3([H])C([H])([H])C3([H])[H])=C(OC([H])(F)F)C([H])=C2[H])=C1[H])C([H])([H])[H]
[H]N([H])[C@@]([H])(C([H])([H])C(=O)N([H])C1(C2=NC3=C(S2)C([H])=C(OC([H])([H])C([H])([H])OC([H])([H])[H])C([H])=C3[H])C([H])([H])C([H])([H])S(=O)(=O)C([H])([H])C1([H])[H])C([H])([H])C1=C(F)C([H])=C(F)C(F)=C1[H]
[H]N1C(=C([H])C(=C1C1=C([H])C([H])=NC([H])=C1[H])C1=C(OC([H])(C([H])([H])[H])C([H])([H])[H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]OC1=C([H])C([H])=C([H])C2=C1SC(=C2[H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])[C@]([H])(O[H])C([H])([H])OC2=C([H])C([H])=C([H])C3=C2C([H])=C([H])N3[H])C([H])([H])C1([H])[H]
[H]OC1=C(O[H])C(F)=C(OC([H])([H])[C@]([H])(O[H])C([H])([H])N([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])=C1[H]
[H]N(C(=O)[C@@](N([H])C(=O)OC([H])([H])C1=C([H])C2=C(O1)C([H])=C([H])C([H])=C2[H])(C([H])([H])[H])C([H])([H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H])[C@]([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H]
[H]N(C1=NC(=C([H])S1)C1=NC([H])=C([H])C([H])=C1[H])C([H])([H])[C@]1([H])[C@]2([H])C([H])([H])N(C([H])([H])C3=C([H])C(=C([H])C(=C3[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])[C@]12[H]
[H]OC1=C(\C([H])=C(/[H])C([H])([H])[C@]2([H])C(=C([H])[H])C([H])=C(C([H])([H])[H])C([H])([H])C2(C([H])([H])[H])C([H])([H])[H])C([H])=C(OC([H])([H])[H])C(Br)=C1[H]
[H]OC(=O)C1=C([H])C2=C(OC([H])([H])C3=C(C([H])=C([H])C([H])=C3[H])\C2=C(\[H])C([H])([H])N2C([H])=NC3=C2C([H])=C(OC([H])([H])[H])C(OC([H])([H])[H])=C3[H])C([H])=C1[H]
[H]OC(=O)C([H])([H])OC1=C([H])C([H])=C([H])N2C1=C(C(=O)C(=O)N([H])[H])C(SC([H])([H])[H])=C2C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N1N=NC(=N1)C1=C(C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1N=C(S\C1=N/C(=O)C1=C(C([O-])=O)C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C([H])([H])[H]
[H]OC(C1=C([H])C([H])=C([H])C([H])=C1[H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H]
[H]OC(=O)[C@@]([H])(C1=C([H])C([H])=C(C(F)=C1[H])C1=C(OC([H])([H])C([H])([H])[H])C([H])=C([H])C([H])=C1OC([H])([H])C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])C([H])=C2C(C([H])=C([H])C([H])=C2C2=C([H])C([H])=C(C([H])=C2OC([H])([H])[H])C(=O)N2C([H])([H])[C@]3(C([H])([H])[H])C([H])([H])[C@@]2([H])C([H])([H])C(C([H])([H])[H])(C([H])([H])[H])C3([H])[H])=C1[H]
[H]N(C(=O)C1=C([H])C2=C(C([H])=C([H])C([H])=C2[H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C1([H])[H])C([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]SC([H])([H])[C@]1(C(=O)N([H])[C@]([H])(C(=O)N([H])C2=NC([H])=C([H])C([H])=C2[H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])[C@]([H])(OC([H])([H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N(\N=C(\OC1=C([H])C(=C([H])C([H])=C1[H])C([H])([H])[H])C(=O)C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1C#N
[H]N(C1=NC(=C([H])C([H])=N1)C1=C([H])C2=C(S1)C([H])=C([H])C([H])=C2[H])C1=C([H])C([H])=C(C(=O)N2C([H])([H])C([H])([H])C([H])(N3C([H])([H])C([H])([H])C([H])([H])C3([H])[H])C([H])([H])C2([H])[H])C(OC([H])([H])[H])=C1[H]
[H]OC1=C([H])C2=C(N=C(S2)S(=O)(=O)N([H])C(=O)C([H])([H])N(C(=N[H])N([H])[H])C([H])([H])[H])C([H])=C1[H]
[H]N1C2=C(C([H])=C1C1=C([H])C([H])=NC(\C([H])=C(/[H])C3=C([H])C([H])=C(C([H])=C3[H])C([H])([H])N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H])=C1[H])C(=O)N([H])C([H])=N2
[H]O[C@@]1([H])[C@@]([H])(O[C@]([H])(C(=O)N([H])C([H])([H])C([H])([H])[H])[C@@]1([H])O[H])N1C([H])=NC2=C1N=C(Cl)N=C2N([H])N([H])C(=O)C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC1=C(\N=N\C2=C(O[H])C([H])=C(C3=C2C([H])=C([H])C([H])=C3[H])S(=O)(=O)O[H])C(=NN1C1=C([H])C([H])=C(C([H])=C1[H])[N+]([O-])=O)C([H])([H])[H]
[H]N(C1=NC(C2=C([H])C([H])=C([H])O2)=C(S1)C(=O)C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[C@@]([H])(OC([H])([H])[H])C([H])([H])[H]