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[H]O[C@]1(C([H])([H])[H])C([H])([H])[C@]([H])(C2=NC(=C3N2N=C([H])N=C3N([H])[H])C2=C([H])C3=C(C([H])=C([H])C(=N3)C3=C([H])C([H])=C([H])C([H])=C3[H])C([H])=C2[H])C1([H])[H]
[H]N(C1=NC2=C(SC([H])=C2[H])C(=N1)N(C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H])C1=C(C([H])=C(OC([H])([H])[H])C([H])=C1[H])C([H])([H])[H]
[H]N([H])C(=O)C1=C2N([H])C3=C(C([H])=C(OC([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H])C([H])=C3[H])C([H])([H])C([H])([H])N2N=C1C1=C([H])C([H])=C(OC2=C([H])C([H])=C([H])C([H])=C2[H])C([H])=C1[H]
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[H]OC1=C([H])C([H])=C(C([H])=N1)C(=O)N([H])C([H])([H])C([H])([H])[C@@]([H])(C1=C([H])C([H])=C(F)C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)C([H])([H])[H]
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[H]N([H])C1=C([H])C2=C(N=C(SC([H])([H])C(=O)N([H])C3([H])C([H])([H])C([H])([H])N(C([H])([H])C4=C([H])C(Cl)=C(Cl)C([H])=C4[H])C([H])([H])C3([H])[H])S2)C([H])=C1[H]
CC1=CN=C(NCCC2=CC=CC=C2)C(=O)N1CC(=O)NCC1=CC=C(S1)C(=N)NO[Si](C)(C)C(C)(C)C
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[H]N(C([H])([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])[C@]1([H])C([H])([H])N(C(=O)N2C([H])([H])C([H])([H])[C@]([H])(N(C(=O)C3=C([H])C([H])=C(C([H])=C3[H])C3=C([H])C([H])=C(Cl)C([H])=C3[H])C([H])([H])[H])C2([H])[H])C([H])([H])C1([H])[H]
[H]O[C@]([H])(C([H])([H])C([H])([H])[H])C([H])([H])[C@]([H])(O[H])[C@@]([H])(N([H])C(=O)C([H])([H])N([H])C(=O)[C@@]([H])(N([H])S(=O)(=O)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]C1=C(OC2=C([H])C([H])=C([H])C([H])=C12)C([H])([H])N1C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]C1=C([H])C(=C([H])C(=C1C([H])([H])[H])C([H])([H])[H])S(=O)(=O)N(C([H])([H])[H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N(C1=NC([H])=C([H])C(=N1)C1=C([H])C([H])=C(N=C1[H])N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H])C1=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C(OC([H])([H])[H])=C1[H]
[H]N(C(=O)C1=C(C([H])=C([H])C([H])=C1[H])C([H])([H])[H])[C@@]([H])(C(=O)N1C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])OC2=C([H])C([H])=C(C3=NOC(=N3)C([H])([H])C3([H])C([H])([H])C([H])([H])C([H])([H])C3([H])[H])C(F)=C2[H])C([H])([H])C1([H])[H])C([H])([H])[H]
COC1=CC=C(OC2=C(Cl)C=NN(CC3=CC=CC=C3N3C=CC=N3)C2=O)C=C1
[H]N(C(=O)C(=O)OC([H])([H])C([H])([H])[H])C1=C([H])C(Cl)=C(OC2=C([H])C3=C(N([H])C([H])=C3C([H])(C([H])([H])[H])C([H])([H])[H])C([H])=C2[H])C(=C1[H])C([H])([H])[H]
[H]C1=C([H])C(=C([H])C([H])=C1OC1=C(N(N=C1C([H])([H])[H])C1=C([H])C(Cl)=C(C#N)C([H])=C1[H])C([H])([H])[H])C(=O)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
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[H]N([H])C1=NC(=C([H])C(=N1)C1=C(C#N)C([H])=C([H])C([H])=C1[H])C(=O)N([H])C([H])([H])C1=NC([H])=C([H])C([H])=C1[H]
[H]OC(=O)C([H])([H])N(C([H])([H])C(=O)O[H])C([H])([H])C([H])([H])N(C([H])([H])C(=O)O[H])C([H])([H])C([H])([H])N(C([H])([H])C(=O)O[H])C([H])([H])C(=O)N([H])[C@]([H])(C(=O)N1C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N1C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)OC([H])([H])[H])C([H])([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(O[H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])N=C(N([H])[H])N([H])[H])C1([H])C([H])([H])C([H])([H])N(C(=N[H])N([H])[H])C([H])([H])C1([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])[H]
[H]N([H])C(=O)C1=C(N([H])C(=O)N(C(=O)N2C([H])([H])C([H])([H])C([H])(N3C([H])([H])C([H])([H])C(C(=O)OC([H])([H])[H])(C4=C([H])C([H])=C([H])C([H])=C4[H])C([H])([H])C3([H])[H])C([H])([H])C2([H])[H])[C@@]1([H])C1=C(F)C([H])=C(F)C([H])=C1[H])C([H])([H])C([H])([H])[H]
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[H]OC([H])([H])C1=C(N=C2C([H])=C([H])C([H])=C([H])C2=C1N([H])C1=C([H])C([H])=C(C([H])=C1[H])N1C([H])([H])C([H])([H])N(C([H])([H])[H])[C@@]([H])(C([H])([H])[H])C1([H])[H])C([H])([H])[H]
NC(=O)C1=CC2=NC=NC(N3CCC(CN4CCCC4)CC3)=C2S1
[H]OC1(C2=C([H])C([H])=C(F)C([H])=C2[H])C([H])([H])C([H])([H])N(C(=O)C2=NN(C(=C2C([H])([H])C#N)C2=C([H])C([H])=C(Cl)C([H])=C2[H])C2=C([H])C([H])=C([H])C([H])=C2Cl)C([H])([H])C1([H])[H]
[H]OC([H])([H])C1=NN(C(=C1C1=C([H])C([H])=C(C([H])=C1C(=O)N1C([H])([H])C2=C(C([H])=C([H])C([H])=C2[H])C([H])([H])[C@@]1([H])C([H])([H])N([H])[H])C(=O)N([H])S(=O)(=O)C1=C([H])C([H])=C2C([H])=C([H])C([H])=C([H])C2=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N([H])C1=C2C(=NC([H])=N1)N(C([H])=C2C1=C([H])C([H])=C(C([H])=C1[H])C(=O)OC([H])([H])C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC([H])([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])N([H])C(=O)C1=C([H])C2=C([H])C(C#N)=C([H])C([H])=C2N1C([H])([H])C1=C([H])C(Br)=C([H])C([H])=C1OC([H])([H])[H]
COC1=NC(=NC(C)=C1F)N1C[C@H]2C(=O)N(C)C(=N)N[C@]2(C1)C1=C(F)C=CC(F)=C1F
[H]O[C@]1([H])[C@]([H])(C2=C([H])C(=C(C([H])=C([H])[H])C(=C2N([H])C1(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C([H])C2=C1N([H])C([H])=C2[H])C([H])([H])[H]
[H]N(\N=C(/[H])C1=C([H])C([H])=NC([H])=C1[H])C1=C2C([H])=NN(C2=NC([H])=N1)C1=C([H])N=C([H])C([H])=C1[H]
[H]N(C(=O)C([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C1=NC2=C(C([H])=C([H])C([H])=C2[H])C2=C([H])N(N=C12)C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]C1=NN2N=C(C(=C2C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)C([H])([H])[H])C1=C([H])C([H])=C(OC([H])([H])C([H])([H])[H])C([H])=C1[H]
[H]C1=C([H])N(C2=NC(=C(N12)C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C1([H])C([H])([H])C1([H])[H])C(F)(F)F)C1=C(C([H])=C(C([H])=C1C([H])([H])[H])C([H])([H])[H])C([H])([H])[H]
[H]OC(=O)C1=C([H])C2=C(OC([H])([H])C3=C(C([H])=C([H])C([H])=C3[H])\C2=C(\[H])C([H])([H])N2C([H])=NC3=C2C([H])=C(C([H])=C3[H])[N+]([O-])=O)C([H])=C1[H]
[H]N1C([H])=C(C(=O)C2=C([H])C([H])=C(C([H])=C2[H])C([H])([H])N2C(=NC3=C2C([H])=C([H])N=C3[H])C([H])([H])[H])C2=C([H])C([H])=C([H])C(=C12)C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]OC(=O)C(OC1=C2C(=C([H])C([H])=C1[H])N(C([H])([H])C([H])([H])C([H])([H])OC1=C(C([H])=C(C([H])=C1[H])C(=O)C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C2([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])C(=NC(=C1F)C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1C(=O)N(C(=O)C1([H])[H])C([H])([H])C([H])(F)F
[H]OC(=O)C([H])([H])C([H])([H])[C@]([H])(N([H])C(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C(OC([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])=C1[H]
[H]N=C(N([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])[C@]1([H])N2C([H])([H])C([H])([H])C([H])([H])[C@@]2([H])[C@@]2([H])C(=O)N(C(=O)[C@@]12[H])C([H])([H])C1=C([H])C(F)=C([H])C([H])=C1[H]
[H]C1=C([H])N(C([H])=N1)C([H])([H])[C@@]([H])(OC([H])([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]ON([H])C(=O)C1=C([H])N=C2C(C([H])=C([H])[H])=C([H])C([H])=C([H])C2=C1N(C([H])([H])[H])S(=O)(=O)C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]\C(=C(\[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])N2C1=NC(=C2C([H])([H])C#N)C([H])([H])[H]
[H]OC1=C([H])C([H])=C(C([H])=C1\C([H])=C(/[H])C([H])([H])N([H])C(=O)C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)N([H])[H])C(=N[H])N([H])[H]
[H]OC1=C([H])C([H])=C(OC2=C(C([H])=C(C([H])=C2[H])C([H])([H])C([H])([H])N([H])[H])C([H])([H])[H])C([H])=C1[H]
[H]N([H])C(=O)C1=C(OC([H])([H])C2=C(Cl)C([H])=C([H])C([H])=C2[H])C([H])=C(S1)C1=C([H])N=C2C([H])=C([H])C([H])=C([H])N12
[H]O[C@]([H])(C1=C([H])C([H])=C([H])N=C1[H])C([H])([H])N([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C(N([H])S(=O)(=O)C2=C([H])C([H])=C(C([H])=C2[H])C2=NOC(=N2)C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])=C1[H]
[H]OC(=O)C([H])([H])[C@]([H])(N([H])C(=O)C([H])([H])N([H])C(=O)[C@@]([H])(N([H])C(=O)C([H])([H])N([H])[H])C([H])([H])C([H])([H])C([H])([H])N=C(N([H])[H])N([H])[H])C(=O)N([H])[C@]([H])(C(=O)O[H])C([H])([H])O[H]
[H]O[C@@]12N(C([H])([H])C([H])([H])C3=C([H])C([H])=C(OC([H])([H])[H])C(OC([H])([H])C([H])([H])C4=C([H])C([H])=C([H])C([H])=C4[H])=C3[H])[C@@]3([H])[C@]4([H])[C@@]5([H])[C@@]([H])([C@]14[H])[C@]1([H])C([H])([H])[C@@]5([H])[C@@]3([H])[C@]21[H]
COC1=CC2=C(CN(C[C@]3(NC(=O)NC3=O)C#CC3=CC=CN=C3N3CCOCC3)C2=O)C=C1
[H]N([H])C1=NC2=C(C([H])=NN2C([H])([H])C([H])([H])N2C([H])([H])C([H])([H])N(C3=C([H])C([H])=C(OC([H])([H])C([H])([H])OC([H])([H])[H])C([H])=C3F)C([H])([H])C2([H])[H])C2=NN(C(=O)N12)C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C([H])=C([H])C(=O)N([H])C1=C(C([H])=C2N=C([H])N=C(N([H])C3=C([H])C(Cl)=C(F)C([H])=C3[H])C2=N1)C([H])([H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]N(C(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C(\[H])=C(\[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C1=C(OC([H])([H])[H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]OC1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)C([H])([H])[H])C([H])([H])[H])C([H])([H])O[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])N=C(N([H])[H])N([H])[H])C([H])([H])C1=C([H])N([H])C([H])=N1)C([H])([H])C1=C([H])C([H])=C(O[H])C([H])=C1[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C(=O)N([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])[C@]([H])(O[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])N=C(N([H])[H])N([H])[H])C([H])([H])C([H])([H])C(=O)N([H])[H])C([H])([H])C([H])([H])C([H])([H])N=C(N([H])[H])N([H])[H])C(=O)N([H])[H]
[H]ON([H])C(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C(=O)N([H])C1=C(OC([H])([H])[H])C([H])=C(O[H])C(=C1[H])C(=O)N([H])C1=C([H])C([H])=C(F)C(Cl)=C1[H]
[H]OC(=O)[C@]([H])(C1=C([H])C(=C([H])C(=C1[H])C(F)(F)F)N(C(=O)C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(N([H])C(=O)C2=C(Cl)C([H])=C([H])C([H])=C2Cl)C([H])=C1[H]
[H]N([H])C1=NC(=C(C(=N1)N([H])[H])C1=C([H])C([H])=C([H])C(Cl)=C1[H])C([H])([H])C([H])([H])C([H])([H])OC(=O)C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@]([H])(N([H])[H])C(=O)N([H])C([H])([H])C([H])([H])C([H])([H])[C@]([H])(N([H])C1=C2N=C([H])C([H])=C([H])C2=C([H])C(OC([H])([H])[H])=C1[H])C([H])([H])[H]
[H]OC(=O)C1=C(C(=NN1C([H])([H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1OC([H])([H])C(=O)O[H])C1=C([H])C([H])=C([H])S1)C([H])([H])C1=C([H])C2=C(OC([H])([H])O2)C([H])=C1Cl
[H]N(C(=O)C1=C([H])C2=C(N([H])C([H])=C2[H])C([H])=C1[H])C1=C(C#N)C([H])=NC2=C1C([H])=C(S2)C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N=C(N([H])[H])C1=C([H])SC(=N1)C([H])([H])N([H])C(=O)C([H])([H])N1C([H])=C([H])C([H])=C(N([H])S(=O)(=O)C2=C([H])C([H])=C([H])C(OC([H])([H])[H])=C2[H])C1=O
[H]OC1=C([H])C(=C(C(=C1[H])C([H])([H])[H])C([H])([H])[C@]([H])(N([H])[H])C(=O)N([H])[C@@]([H])(C(=O)N([H])[C@@]1(C(=O)N(C([H])([H])C(=O)N([H])[H])C([H])([H])C2=C(C([H])=C([H])C([H])=C2[H])C1([H])[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])[H]
[H]N([H])C1=C2C(=NC3=C([H])C([H])=C([H])C(Cl)=C13)[C@]1([H])C([H])([H])C([H])([H])[C@@]2([H])C1([H])[H]
[H]C1=C([H])C([H])=C2C(=C1[H])C(=O)N(C([H])([H])OP(=O)(OC([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])OC([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])S2(=O)=O
[H]N(C(=O)C([H])([H])[H])C1(C2=NC(=C([H])C([H])=C2[H])C2=C([H])C3=C(N=C(N([H])C([H])([H])[H])C4=C3N(C([H])=N4)C([H])([H])[H])N2[H])C([H])([H])C1([H])[H]
[H]C1=C([H])C(C(=O)OC([H])([H])[H])=C2C(OC([H])([H])[C@@]([H])(N(C([H])([H])C([H])([H])C([H])([H])[H])C3([H])C([H])([H])C([H])([H])C([H])([H])C3([H])[H])C2([H])[H])=C1[H]
[H]O[C@]1([H])[C@]2(O[C@@]2([H])[C@]2([H])O[C@]22[C@]11O[C@@]1([H])C([H])([H])[C@@]1([H])C3=C(C(=O)OC3([H])[H])C([H])([H])C([H])([H])[C@]21C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])C(=C([H])C([H])=C1OC([H])([H])[H])N1C([H])([H])C([H])([H])N(C(=O)C([H])([H])C([H])([H])C2=NC(=NO2)C2=C([H])C([H])=C(OC([H])([H])[H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]OC(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)C([H])([H])N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)C([H])([H])N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)C([H])([H])N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)C([H])([H])N([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C(=O)N([H])[H])C([H])([H])C([H])([H])C([H])([H])N=C(N([H])[H])N([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C(=O)N([H])[H])C([H])([H])C([H])([H])C([H])([H])N=C(N([H])[H])N([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C(=O)N([H])[H])C([H])([H])[H])C([H])([H])O[H])C([H])([H])[H])C([H])([H])C1=C([H])N([H])C([H])=N1)C([H])([H])[H])C([H])([H])[H])[C@@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])[C@]([H])(O[H])C([H])([H])[H])C([H])([H])C([H])([H])SC([H])([H])[H]
[H]N(C(=O)N([H])C1=C([H])C([H])=C([H])C([H])=C1Cl)C1=C(N([H])C(=C1[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C(=O)OC([H])([H])[H]
[H]N(C(=O)N(C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])C1([H])[H])[C@@]1([H])C([H])([H])C([H])([H])[C@@]2(C3=C([H])C([H])=C([H])C(C#N)=C3[H])C([H])([H])[C@@]12[H])C1=C([H])C(Cl)=C([H])C(Cl)=C1[H]
[H]OC1=NC2=C([H])C(Cl)=C(C([H])=C2C(OC([H])([H])C([H])([H])[C@]2([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[N+]2([H])[H])=C1C1=C([H])C(=C([H])C(=C1[H])C([H])([H])[H])C([H])([H])[H])C(=O)N([H])C1=NC([H])=NC(=C1[H])C([H])([H])[H]
[H]N(C(=O)N([H])C([H])([H])C([H])([H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)N([H])C([H])([H])C([H])([H])Cl)C1=C([H])C2=C(N=C([H])N=C2C([H])=C1[H])N([H])C1=C([H])C(Br)=C([H])C([H])=C1[H]
[H]N([H])C1=NC(=C(N=N1)C1=C([H])C(=C([H])C(=C1[H])C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)C([H])([H])[H])C([H])([H])C([H])([H])C1=C([H])C([H])=[N+](C2=C([H])C([H])=C(OC([H])([H])[H])C([H])=C12)C([H])([H])[H]
Cc1cnc(N[C@H]2CCC[C@H]2O)nc1-c1c[nH]c(c1)C(=O)N[C@H](CO)c1cccc(Cl)c1
[H]N1N=NC(=N1)C1=C([H])C([H])=C([H])C([H])=C1C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1C(=O)N(N=C1C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1C(=O)OC([H])([H])[H]
[H]OC1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[C@]([H])(N([H])[H])C(=O)N1C([H])([H])SC([H])([H])[C@]1([H])C(=O)N([H])[C@@]([H])(C(=O)N([H])[C@@]([H])(C(=O)N([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
OC(=O)CC1=CC(Br)=C(N(CC2=CC=CC=C2)CC2=CC=C(OC3=CC=CC=C3)C=C2)C(Br)=C1
[H]OC([H])([H])[C@@]1([H])O[C@@]([H])(N2C([H])=NC3=C(N=C(N=C23)C#CC2=C([H])C([H])=C([H])N=C2[H])N([H])OC([H])([H])[H])[C@]([H])(O[H])[C@]1([H])O[H]
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[H]OC(=O)[C@]([H])(N([H])C(=O)[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])N(C2=C1C([H])=C([H])C([H])=C2[H])C([H])([H])[H])C([H])([H])C1=NC([H])=C([H])C([H])=C1[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])[C@@]1([H])SC(=N[C@]1([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H]
[H]N([H])C1=NN([H])C2=C1C(=C([H])N=C2[H])C1=C([H])C([H])=C(N([H])C(=O)N([H])C2=C([H])C(=C([H])C([H])=C2F)C(F)(F)F)C([H])=C1[H]
[H]N([H])C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)N1C([H])=C(C2=C1C([H])=C([H])C(OC([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])=C2[H])C1=C([H])C([H])([H])N([H])C([H])([H])C1([H])[H]
[H]N(C1=NN=C(O1)C1=C([H])C([H])=NC([H])=C1C([H])([H])C([H])([H])C1=C([H])C([H])=NC([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]OC(=O)C([H])([H])[C@]([H])(N([H])C(=O)[C@]([H])(N([H])[H])C([H])([H])C1=C([H])C([H])=C(O[H])C([H])=C1[H])C(=O)N([H])C([H])([H])C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N1C([H])([H])C([H])([H])C([H])([H])[C@]1([H])C(=O)N([H])[C@@]([H])(C(=O)N([H])[C@@]([H])(C(=O)N([H])[C@@]([H])(C(=O)N([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])[H])C([H])([H])C([H])([H])C([H])([H])N=C(N([H])[H])N([H])[H])[C@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])N=C(N([H])[H])N([H])[H])C([H])([H])C([H])([H])C([H])([H])N=C(N([H])[H])N([H])[H])C([H])([H])C([H])([H])C([H])([H])N=C(N(C([H])([H])[H])C([H])([H])[H])N(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C1=NN=C([H])C2=C(OC3([H])C([H])([H])C([H])([H])C([H])([H])C3([H])[H])C(OC([H])([H])[H])=C([H])C([H])=C12)C1=C(Cl)C([H])=NC([H])=C1Cl
[H]OC(=O)C1=C([H])C([H])=C([H])C2=C1C1=C(N(C(=N1)N1C([H])([H])C([H])([H])C([H])([H])[C@@]([H])(N([H])[H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1Cl)C(=O)N2C([H])([H])[H]
[H]N(C(=O)N([H])C1=C([H])C([H])=C(Cl)C(Cl)=C1[H])C1=C(C([H])=C(S1)C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C(=O)N1C([H])([H])C([H])([H])N([H])C(=O)C([H])([H])C1([H])[H]
[H]N1C(=C([H])C2=C1C([H])=C([H])C(Cl)=C2[H])C(=O)N1C2=C([H])C([H])=C([H])C([H])=C2[C@@]2(C1([H])[H])C([H])([H])N(C([H])([H])C2([H])[H])[C@@]1([H])C([H])([H])N([H])C([H])([H])C1([H])[H]
[H]N(C(=O)N1C2=C(C([H])=C3N(C([H])=C([H])C3=C2[H])C([H])([H])[H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C([H])N=C1[H]
[H]N(C(=O)N([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C([H])C([H])=C1C([H])([H])N1C([H])([H])C([H])([H])C([H])(C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]OC1=C([H])C([H])=C(C([H])=C1[H])N(C(=O)C1=C([H])C([H])=C([H])C(F)=C1C([H])([H])[H])C1=C([H])C([H])=C(O[H])C([H])=C1[H]
[H]N(C(=O)C([H])([H])[H])C1=NC(C2=C([H])C([H])=C([H])O2)=C(C([H])=C1[H])C1=NC([H])=NC([H])=C1[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])[C@@]([H])(N1C([H])=C([H])C([H])=C(C2=C([H])C3=C([H])C([H])=C([H])C([H])=C3C([H])=C2[H])C1=O)C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]O[C@]([H])(C(=O)N1C([H])([H])SC(C([H])([H])[H])(C([H])([H])[H])[C@@]1([H])C(=O)N([H])[C@@]1([H])C2=C([H])C([H])=C([H])C([H])=C2C([H])([H])[C@@]1([H])O[H])[C@@]([H])(N([H])C(=O)C([H])([H])OC1=C(C([H])=C([H])C([H])=C1C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C1=C([H])C(OC([H])([H])[H])=C2C(=C1[H])C([H])([H])[C@@]([H])(N(C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[H])C2([H])[H]
[H]C1=C2N(C(=O)C(=C(C#N)C#N)C2=C([H])C(=C1[H])S(=O)(=O)N1C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]N1C(=C([H])C2=C1C([H])=C([H])C([H])=C2[H])C(=O)C1=C([H])C2=C(N1[H])C([H])=C([H])C(OC(=O)C([H])([H])C1=C([H])C([H])=C([H])S1)=C2[H]
[H]OC1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1C([H])=NC2=NC([H])=C(Br)C([H])=C12
[H]OC(=O)[C@@]([H])(N([H])C(=O)C1=C(OC2=C([H])C([H])=C([H])C([H])=C2[H])C([H])=C([H])C([H])=C1[H])C([H])([H])SC([H])([H])C(\[H])=C(/C([H])([H])[H])C([H])([H])C([H])([H])C(\[H])=C(/C([H])([H])[H])C([H])([H])C([H])([H])C([H])=C(C([H])([H])[H])C([H])([H])[H]
COC1=C(F)C2=C(CN(C[C@]3(CC(=O)NC3=O)C#CC3=CC=C(C=C3)C3=NC(=CC=C3O)N3CCC(=O)CC3)C2=O)C=C1
[H]OC1=C([H])C([H])=C2C(=C1[H])C([H])([H])C([H])([H])N(C(=O)C1=C([H])C([H])=C([H])C([H])=C1[H])[C@@]2([H])C1=C([H])C([H])=C(OC([H])([H])C([H])([H])N2C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])=C1[H]
[H]C1=C(C(C(=O)C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H])=C(C([H])=C1SC([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])[H])C([H])([H])[H]
[H]ON([H])C(=O)[C@@](C([H])([H])[H])(C([H])([H])C1=C([H])C([H])=C(OC([H])([H])N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H])C([H])=C1[H])S(=O)(=O)C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C([H])O1
[H]N([H])S(=O)(=O)OC1=C([H])C([H])=C(N([H])C(=O)N([H])C2=C([H])C([H])=C([H])C([H])=C2C(=O)OC([H])([H])C([H])([H])[H])C([H])=C1[H]
[H]N([H])C1=NC(=NN1C1=NC([H])=C(C#N)C([H])=C1[H])N([H])C1=C([H])C([H])=C(C([H])=C1OC([H])([H])[H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]OC1=C([H])C([H])=C2N([H])C([H])=C(C2=C1[H])C([H])([H])C([H])([H])N([H])C([H])([H])[H]
CCOC(=O)CNC(=O)C1=CC2=C(CCC3=C(C=CC(NC4=C(F)C=C(F)C=C4)=C3)C2=O)C=C1
[H]N([H])S(=O)(=O)C1=C([H])C([H])=C2C(=C1[H])[C@@]([H])(N([H])C([H])([H])[H])C([H])([H])C([H])([H])[C@@]2([H])C1=C([H])C([H])=C(Cl)C(Cl)=C1[H]
[H]N([H])C([H])([H])C([H])([H])[C@@]([H])(OC1=C2C([H])=C([H])C([H])=C([H])C2=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])S1
[H]C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C(=O)C2=C(O1)C([H])=C(C([H])=C2C(=O)C([H])([H])[H])C(=O)C([H])([H])[H]
[H]N([H])C(=O)C1=C([H])C([H])=C2N([H])C(=NC2=C1[H])C1=C([H])C([H])=C(OC2=C([H])C(Cl)=C(Cl)C([H])=C2[H])C([H])=C1[H]
[H]OC(=O)C([H])([H])[C@]([H])(SC([H])([H])C1=C2S[C@@]([H])(C([H])([H])[H])C([H])([H])C3=C2C(=C([H])C([H])=C3OC([H])([H])C2=C([H])C([H])=C(C([H])=N2)C2=C([H])C([H])=C([H])C([H])=C2[H])N1C([H])([H])C1=C([H])C([H])=C(Cl)C([H])=C1[H])C([H])([H])[H]
[H]OC1=C(OC([H])([H])[H])C([H])=C(Cl)C(OC([H])([H])[H])=C1C(=O)N([H])C([H])([H])[C@@]1([H])N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C1([H])[H]
[H]C1=NC([H])=C(N1C([H])([H])C1=C([H])N=C(C#N)C([H])=C1[H])C([H])([H])OC([H])([H])C1=C(C([H])=C(C#N)C([H])=C1[H])C1=C([H])C([H])=C([H])C(OC([H])([H])C([H])([H])[H])=C1[H]
[H]OC1(C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])[C@]([H])(C(=N\OC([H])([H])[H])\C([H])([H])OC([H])([H])C2=C([H])C(Cl)=C([H])C(Cl)=C2[H])C2=C([H])C(Cl)=C(Cl)C([H])=C2[H])C([H])([H])C1([H])[H]
[H]OC(=O)C([H])([H])C([H])([H])C([H])([H])[C@]([H])(C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])N=C1[H])C([H])([H])C([H])([H])C([H])([H])N([H])S(=O)(=O)C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]N(C1=C2C(=NC3=C(C([H])=C(OC([H])([H])[H])C([H])=C13)C([H])([H])[H])N([H])N=C2C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=N1
FC1=CC=C2C=CC=C(N3CCN(CCCOC4=C(F)C=C5CNC(=O)C5=C4)CC3)C2=C1
[H]C1=NC([H])=C([H])C(=C1[H])N1C([H])([H])C2=C(C([H])=C([H])C([H])=C2Cl)C([H])([H])C1([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C(C([H])=C1[H])C(\C#N)=C1/C([H])([H])[C@@]2([H])N(C([H])([H])C3=C([H])OC([H])=C3[H])[C@]([H])(C([H])([H])C2([H])[H])C1([H])[H])C([H])([H])C([H])([H])[H]
[H]OC(=O)C([H])([H])[C@]([H])(N([H])C(=O)C([H])([H])C([H])([H])N([H])C(=O)C1=C([H])C([H])=C(C([H])=C1[H])C(=N[H])N([H])[H])C(=O)N([H])[C@]([H])(C(=O)O[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C(OC([H])([H])C([H])([H])N2C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])=C1[H]
COC1=CC=C2C=C(CNCC3=CC=C(C)C=C3)C(=NC2=C1)C1=CSC=C1
[H]OC([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])C([H])([H])C1=C([H])N([H])C2=C1N=C([H])N([H])C2=O
[H]N([H])C1=NC([H])=NC2=C1C(=C(Cl)N2C1([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C(OC2=C([H])C([H])=C([H])C([H])=C2[H])C([H])=C1[H]
[H]N(C(=O)C1=C([H])C([H])=C([H])S1)C1=NC([H])=C(S1)C([H])([H])C1=C([H])C(=C([H])C([H])=C1[H])C([H])([H])[H]
[H]N(C1=NC(N([H])C([H])([H])[H])=C(C([H])=N1)C(F)(F)F)C1=C([H])C(OC([H])([H])[H])=C(C([H])=C1OC([H])([H])[H])C(=O)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]N(C(=O)C([H])([H])[H])C1=C([H])C2=C(C([H])=C1[H])C(=NN(C2=O)C([H])(C([H])([H])[H])C([H])([H])[H])N([H])C1=NN([H])C(=C1[H])C([H])([H])[H]
[H]C1=C([H])C([H])=C2C3=NN=C(C([H])=C3C(=O)C2=C1[H])C1=C([H])C([H])=C([H])C([H])=C1Cl
[H]N(C(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C(=O)N([H])C1=C([H])C2=C(N([H])C([H])=C2C2([H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C2([H])[H])C([H])=C1[H])C1=C([H])C2=C(N([H])C([H])=C2C2([H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C2([H])[H])C([H])=C1[H]
[H]N1C([H])([H])C([H])([H])C([H])(N(C([H])([H])C2=C([H])C([H])=C(F)C([H])=C2C(F)(F)F)C([H])([H])C([H])([H])C([H])([H])OC([H])([H])[H])C([H])([H])C1([H])[H]
CC1=C(C=C(N1)C1=CC=NC=C1)C(N)=O
[H]N([H])[C@@]([H])(C([H])([H])C(=O)N1C([H])([H])C2=C(N([H])N=C2C([H])([H])[H])C([H])([H])C1([H])[H])C([H])([H])C1=C([H])C(F)=C([H])C([H])=C1F
[H]N([H])S(=O)(=O)C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])OC(=O)N1C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]N([H])C1=NN([H])C2=C1C([H])=C([H])C(=C2[H])C1=C([H])C(=NC(=N1)N([H])[H])N1C([H])([H])[C@]([H])(C(=O)N([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])[C@]1([H])C([H])([H])[H]
[H]C1=C([H])C([H])=C(C(OC2([H])C([H])([H])C([H])([H])N(C3=NC([H])=C(Br)C([H])=C3[H])C([H])([H])C2([H])[H])=N1)C1([H])C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]SC1=NC(=C([H])N1[H])C([H])([H])C([H])([H])N([H])C(=O)C([H])([H])N1C(=O)C([H])([H])N(C([H])([H])C1([H])[H])S(=O)(=O)C1=C([H])C2=C(S1)C([H])=C(Cl)C([H])=C2[H]
[H]N(C(=O)O[C@@]1([H])[C@]([H])([N@]2C([H])([H])C([H])([H])[C@]1([H])C([H])([H])C2([H])[H])C([H])([H])C1=C([H])SC([H])=C1[H])C1=C([H])C([H])=C(Br)C([H])=C1[H]
[H]N([H])C(=O)C1=NN(C2=C1C([H])([H])C([H])([H])N(C2=O)C1([H])C([H])([H])C([H])([H])N(C2=C([H])C([H])=C([H])C([H])=C2C([H])([H])N(C(=O)C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]N([C@@]([H])(C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])C([H])([H])[H])[C@]1([H])C([H])([H])C([H])([H])[C@@]([H])(C(=O)N2C([H])([H])C([H])([H])C(N3C(=O)C([H])([H])C([H])([H])C([H])([H])C3([H])[H])(C3=C([H])C([H])=C([H])C([H])=C3[H])C([H])([H])C2([H])[H])C(C([H])([H])[H])(C([H])([H])[H])C1([H])[H]
[H]N(C(=O)C1=C([H])N=C(N=C1N([H])C([H])([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C#N)C([H])([H])C([H])([H])C1=C([H])C([H])=C(OC2([H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C2([H])[H])C([H])=C1[H]
[H]N(C1=NC([H])=C(N2C([H])=NC([H])=C12)C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C(C([H])=C(C([H])=C1C([H])([H])[H])C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C(Cl)C([H])=C1[H])C1=C([H])C([H])=C([H])N=C1[H]
[H]C1=C(OC2=C1C([H])=C(C([H])=C2[H])C(=O)C1=C([H])C(F)=C([H])C(F)=C1[H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C([H])([H])[H]
[H]\C(=C(\[H])C1=C([H])C([H])=C(Cl)C([H])=C1[H])C(=O)N1C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]C([H])=C([H])C(=O)N([H])C1=C([H])C([H])=C2N=C([H])C(C#N)=C(N([H])C3=C([H])C(Br)=C([H])C([H])=C3[H])C2=C1[H]
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CC(C)Nc1ncc(Cl)c(n1)-c1c[nH]c(c1)C(=O)N(C)[C@H](CO)c1ccccc1
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[H]OC1=C([H])C(=C([H])C([H])=C1[H])[C@@]1(C([H])([H])[H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])[C@@]1([H])C([H])([H])[H]
[H]C1=C([H])C([H])=C(C(OC([H])([H])C([H])([H])C([H])([H])C([H])([H])N2C([H])([H])C([H])([H])N(C3=C([H])C([H])=C(F)C([H])=C3[H])C([H])([H])C2([H])[H])=C1[H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C(OC([H])([H])[H])=C1[H]
[H]N(C(=O)C1=C(Cl)C(=C([H])S1)C([H])([H])N1N=NN=C1[H])C1=C(C([H])=C(Cl)C([H])=C1[H])C(=O)N([H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]C1=C([H])C(=C([H])C2=C([H])C([H])=C(N=C12)C1=C(N=C(O1)C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C([H])([H])[H]
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[H]C1=NC(=C([H])C([H])=C1[H])N1C(=O)N(C([H])([H])C([H])([H])C1([H])[H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])[C@@]([H])(C(=N\OC([H])([H])[H])\C([H])([H])N(C(=O)C2=C([H])C(Cl)=C([H])C(Cl)=C2[H])C([H])([H])[H])C2=C([H])C([H])=C(Cl)C(Cl)=C2[H])C([H])([H])C1([H])[H]
[H]OC(=O)C1=C(C(=O)N([H])C2=C(F)C([H])=C(C([H])=C2F)C2=C(Cl)C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C1([H])[H]
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[H]OC(=O)C([H])([H])N([H])C(=O)[C@]([H])(C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])[C@@]([H])(S[H])C([H])([H])[H]
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[H]N([H])C1=C([H])C([H])=C([H])C([H])=C1N([H])C(=O)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N([H])C([H])([H])C1=C([H])C2=C(S1)C([H])=C([H])C([H])=C2[H]
[H]N([H])C1=NC(=C(S1)C1=NC2=C(C([H])=C([H])C([H])=C2C([H])=C1[H])C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=N1
[H]C1=C(N2N=C(OC([H])([H])[H])C(N(C([H])([H])C3([H])C([H])([H])C([H])([H])C3([H])[H])[C@@]3([H])C([H])([H])OC([H])([H])C3([H])[H])=C2S1)C1=C(OC([H])([H])[H])C([H])=C(C([H])=C1OC([H])([H])[H])C([H])([H])OC([H])([H])C([H])([H])[H]
[H]O[C@@]([H])(C([H])([H])[C@]([H])(O[H])C([H])(C([H])([H])[H])C([H])([H])[H])[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)C1=C([H])C2=C(C([H])=C([H])C([H])=C2[H])N1C(=O)C([H])([H])[H])C([H])([H])C1=C([H])N([H])C([H])=N1)C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]OC(=O)C([H])([H])C1=C([H])C(Br)=C(OC([H])([H])C2([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C(Br)=C1[H]
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[H]OC(=O)C1=C([H])C([H])=C(C([H])=C1[H])C1=NOC(=N1)C1([H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C(=O)N2C([H])([H])C([H])([H])C([H])([H])[C@@]2([H])C2=NC3=C(N2[H])C([H])=C(Cl)C(Cl)=C3[H])C([H])([H])C1([H])[H]
[H]N1C(=NN=C1C1([H])C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C(C([H])=C2[H])C2=NC3=NC(=NC([H])=C3C([H])=C2C2=C([H])C([H])=C([H])C([H])=C2[H])N2C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])C([H])([H])C1([H])[H])C1=NC([H])=C([H])C([H])=C1[H]
OC(=O)C1=C(CCCOC2=CC=CC3=CC=CC=C23)C2=CC=CC=C2N1
[H]OC(=O)C([H])([H])SC1=NC2=C(Br)C(Br)=C(Br)C(Br)=C2N1C([H])([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])F)C([H])([H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C([H])C([H])=C([H])C([H])=C2OC([H])([H])C([H])([H])F)C([H])([H])C1([H])[H]
[H]C1=C2C(=O)N(C(=O)C2=C([H])C(=C1[H])C([H])([H])[H])C1=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C(OC([H])([H])[H])=C1[H]
[H]O[C@]1([H])C([H])([H])C2=NC3=C([H])C([H])=C([H])C([H])=C3C(N([H])[H])=C2C([H])([H])C1([H])[H]
NC1=NC(=CC=N1)N1C=CC2=C1C=C(F)C=C2
[H]N(C(=O)C([H])([H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])C1=C([H])N(C([H])=N1)C1([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N=[S@@](=O)(C1=C([H])C([H])=C(N([H])C2=NC(OC([H])([H])C([H])([H])[H])=C(Br)C([H])=N2)C([H])=C1[H])C([H])([H])C([H])([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[C@]1([H])N(C(=O)C([H])([H])[H])C([H])([H])C([H])([H])C2=C([H])C([H])=C(OC([H])([H])[H])C([H])=C12
[H]N([H])C1=NC([H])=C([H])C(=N1)C1=C(C2=C([H])C(=C([H])C([H])=C2S1)C([H])([H])C1=C([H])C([H])=C([H])C(=C1[H])C(F)(F)F)C([H])([H])[H]
[H]N(C(=O)C1=C(OC([H])([H])[H])C(OC([H])([H])[H])=C([H])C(Br)=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N([H])C(=O)C1=C2C(=C([H])C([H])=C1[H])C([H])([H])C([H])([H])[C@]1([H])N(C(=O)C3=C([H])C4=C(C([H])=C3[H])C([H])([H])C([H])=N4)C([H])([H])C([H])([H])C([H])([H])[C@]21[H]
[H]N(C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C(C#N)C([H])=NC2=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C([H])=C12
[H]N([H])C([H])([H])[C@]1([H])C([H])([H])[C@@]1(C(=O)N(C([H])([H])C([H])=C([H])[H])C([H])([H])C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C1=C([H])C2=NC(=C([H])C([H])=C2C(=C1[H])N1C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])C2=C3OC([H])([H])C(=O)N(C3=C([H])C([H])=C2[H])C([H])([H])[H])C([H])([H])C1([H])[H])C([H])([H])[H]
[H]N1C([H])=NC(=C1[H])C([H])([H])C([H])([H])C#CC([H])([H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C1=C([H])C([H])=C([H])C([H])=C1N1C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C(=O)N([H])[C@]2([H])C3=C(C([H])=C([H])C([H])=C3[H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H])C([H])([H])[H]
[H]OC(=O)C([H])([H])[C@]([H])(N([H])C(=O)[C@]1([H])N(C(=O)[C@@]([H])(N([H])C(=O)C([H])([H])[H])C([H])([H])C2=C([H])N([H])C3=C([H])C([H])=C([H])C([H])=C23)C([H])([H])[C@@]([H])(SC([H])([H])[H])C1([H])[H])C(=O)N([H])[C@]([H])(C(=O)N([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC(=O)C([H])([H])[C@]([H])(N([H])C(=O)[C@@]([H])(N(N([H])[C@]([H])(C(=O)N([H])C([H])([H])C(=O)N([H])[C@@]([H])(C(=O)N([H])[C@]([H])(C(=O)O[H])C([H])([H])C1=C([H])C([H])=C(O[H])C([H])=C1[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C(=O)N(C(=O)N([H])C1=C(Cl)C([H])=C([H])C([H])=C1[H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)O[H])C([H])([H])C1=C([H])N(C(=O)C([H])([H])[H])C2=C1C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]N([H])[C@]1([H])C(=O)N([H])C(=O)[C@](OC2=C([H])C([H])=C(OC3=C([H])C([H])=C([H])C(Cl)=C3[H])C([H])=C2[H])(C1=O)C([H])([H])C([H])([H])OC([H])([H])C([H])([H])[H]
[H]C1=C([H])C2=C(C([H])=C1OC(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C(=O)OC1=C([H])C([H])=C3C(=C1[H])[C@]14C([H])([H])C([H])([H])N(C([H])([H])[C@@]5([H])OC([H])([H])C([H])([H])C5([H])[H])[C@]([H])(C3([H])[H])[C@@]1([H])C([H])([H])C([H])([H])C([H])([H])C4([H])[H])[C@]13C([H])([H])C([H])([H])N(C([H])([H])[C@@]4([H])OC([H])([H])C([H])([H])C4([H])[H])[C@]([H])(C2([H])[H])[C@@]1([H])C([H])([H])C([H])([H])C([H])([H])C3([H])[H]
[H]N(C(=O)O[C@]1([H])[C@]([H])(C2=C(F)C(=C(F)C([H])=C2N([H])C1(C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C([H])C2=C1N([H])C([H])=C2[H])C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C(=O)OC([H])([H])[H]
[H]OC(=O)C([H])([H])C([H])([H])[C@@]([H])(OC1=C([H])C(OC([H])([H])C2=C([H])C([H])=NC([H])=C2[H])=C([H])C([H])=C1C#N)C1=C([H])C([H])=C([H])C([H])=C1C([H])([H])[H]
[H]OC(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C(\[H])=C(/C1=C([H])C([H])=C([H])N=C1[H])C1=C(C([H])=C([H])C([H])=C1[H])C1=NC(=C([H])O1)C(=O)N([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]C1=C([H])C2=C(O1)C(=C([H])C([H])=C2[H])N1C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])C(=O)C2=C([H])C([H])=C(F)C([H])=C2[H])C([H])([H])C1([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])N(C(=O)C([H])([H])[H])C([H])([H])C([H])([H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N1C2=C(N=C1C1([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C(=O)N(C(=O)N2C([H])([H])[C@]([H])(F)C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]OS(=O)(=O)C1=C([H])C([H])=C(C([H])=C1[H])C1=NC2=C(N1[H])N(C(=O)N(C2=O)C([H])([H])[H])C([H])([H])[H]
[H]N1N=C2N(C1=S)C1=C([H])C([H])=C([H])C([H])=C1C(=O)N2C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])[H]
[H]N1C([H])([H])[C@@]2([H])C([H])([H])[C@]([H])(OC3=C([H])C([H])=C([H])C([H])=C3C3=C(F)C([H])=C([H])N=C3[H])[C@]([H])(C2([H])[H])C1([H])[H]
[H]N(C(=O)C([H])([H])N1C([H])([H])C([H])([H])N(C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H])[C@@]([H])(C([H])([H])N(C(=O)C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1OC([H])([H])[H])C([H])([H])C1=C([H])SC2=C([H])C([H])=C([H])C([H])=C12
[H]O[C@](C1=C([H])C2=C([H])C(=C(C([H])=C2N1[H])C(F)(F)F)[N+]([O-])=O)(C([H])([H])[H])C([H])([H])OC(=O)C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]N(C(=O)C1=C(N(C(=C1[H])C1=C([H])C([H])=C(Cl)C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C([H])C([H])=C([H])C(=C2C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]OC1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)C([H])([H])[H])C([H])([H])C1=C([H])N=C([H])N1[H])C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[H])C([H])([H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=N[H])N([H])[H]
[H]OC(=O)[C@]([H])(N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])N([H])C(=O)C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC(=O)C1=NOC(=C1[H])C1=C([H])C2=C(C([H])=C1[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C([H])([H])C2(C([H])([H])[H])C([H])([H])[H]
[H]N1C2=C(C([H])=C(C([H])=C2[H])C(=O)C([H])([H])C([H])([H])C2([H])C([H])([H])C([H])([H])N(C([H])([H])C3=C([H])C(=C([H])C([H])=C3[H])[N+]([O-])=O)C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1C([H])([H])C([H])([H])C([H])(C([H])([H])C([H])([H])C(=O)C2=C([H])C3=C4N(C(=O)C([H])([H])C4=C2[H])C([H])([H])C([H])([H])C3([H])[H])C([H])([H])C1([H])[H]
[H]ON([H])C(=O)[C@@]([H])(N([H])S(=O)(=O)C1=C([H])C2=C(N([H])C(=O)C2([H])[H])C([H])=C1[H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])C([H])([H])[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N1C(=O)[C@]([H])(N([H])C(=O)C([H])([H])C([H])(C2=C([H])C([H])=C([H])C([H])=C2[H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C2=C(N([H])C3=C2C([H])=C([H])C([H])=C3[H])C1([H])[H]
COCCNC1=NN=C(SC2=NC=C(S2)N(O)=O)S1
[H]OC(=O)C([H])([H])C([H])([H])[C@@]1([H])C([H])([H])N(C(=O)[C@@]([H])(N([H])C(=O)C([H])([H])C2=C([H])C([H])=C(N([H])C(=O)N([H])C3=C([H])C([H])=C([H])C([H])=C3C([H])([H])[H])C([H])=C2[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C1([H])[H]
[H]OC(=O)C1=C2C(=NN1[H])C([H])([H])OC2([H])[H]
[H]C1=C(ON=C1C1=C(OC([H])([H])[H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])C([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C1=C(F)C(=C([H])C(F)=C1F)N1C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])N2C(=O)C([H])([H])C3(C([H])([H])C([H])([H])C([H])([H])C3([H])[H])C([H])([H])C2=O)C([H])([H])C1([H])[H]
[H]C1=NC(OC2([H])C([H])([H])N(C3=C([H])C([H])=C4C([H])=C([H])C([H])=C([H])C4=N3)C2([H])[H])=C(N=C1[H])C1([H])C([H])([H])C([H])([H])N(C(=O)C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N(C(=O)C([H])([H])[C@]1([H])N(C2=C([H])C([H])=NC(=N2)N2C([H])=NC([H])=C2[H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C1=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]C1=C([H])C([H])=C(OC([H])([H])[C@@]2([H])N(C([H])([H])C2([H])[H])S(=O)(=O)C2=C([H])C3=C(C([H])=C2[H])N(C(=O)C3=O)C([H])([H])C2=C([H])C([H])=C(OC([H])([H])C([H])([H])OC([H])([H])C([H])([H])F)C([H])=C2[H])C([H])=C1[H]
[H]OC(=O)[C@]([H])(N([H])C(=O)C1=C([H])C([H])=C(C([H])=C1[H])N(C([H])([H])C#C[H])C([H])([H])C1=C([H])C2=C(N=C(N=C2O[H])C([H])([H])[H])C([H])=C1[H])C([H])([H])C1=C([H])C(=C([H])C([H])=C1[H])[N+]([O-])=O
[H]OC(=O)C1=C(C2=C([H])C([H])=C([H])C([H])=C2[H])C2=C([H])C(Br)=C([H])C([H])=C2C(=O)N1C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]O[C@]([H])(C(=O)N([H])C1=C([H])C([H])=C(N([H])C(=O)C(\[H])=C(/[H])C2=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C(OC([H])([H])[H])=C2[H])C([H])=C1[H])[C@]([H])(N([H])[H])C([H])([H])C([H])([H])SC([H])([H])C([H])([H])[H]
[H]N(C(=O)[C@@]1(C([H])([H])[H])C([H])([H])C([H])([H])[C@@]([H])(N2C([H])([H])C([H])([H])[C@@]3(C([H])=C([H])C4=C3C([H])=C([H])C([H])=C4[H])[C@@]([H])(C([H])([H])[H])C2([H])[H])C1([H])[H])C([H])([H])C1=C([H])C(=C([H])C(=C1[H])C(F)(F)F)C(F)(F)F
[H]OC(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)OC([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]N1[C@@]2([H])C3=C(N(C4=C(C([H])=C(C([H])=C34)S(=O)(=O)C3=C([H])C([H])=C([H])C([H])=C3[H])N3C([H])([H])C([H])([H])C([H])([H])C3([H])[H])C([H])([H])[H])C([H])([H])[C@]1([H])C([H])([H])C2([H])[H]
[H]ON([H])S(=O)(=O)C1=C([H])C([H])=C(I)C([H])=C1[H]
[H]C1=C([H])C(C2=C3N=C(C([H])=C(N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C3=NN2C([H])([H])C([H])([H])[H])C([H])([H])[H])=C(Cl)C([H])=C1Cl
[H]N(C(=O)N([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C2N(C(SC([H])([H])C3=C(OC([H])([H])[H])C([H])=C([H])C(=C3[H])[N+]([O-])=O)=NC2=C1[H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
C[C@@]1(N=C(N)OCC1(F)F)C1=CC(NC(=O)C2=NC=C(C=C2)C#C)=CC=C1F
[H]C1=C([H])C([H])=C(O1)C1=NN(C(=O)C2=C([H])C([H])=C([H])S2)C(SC([H])([H])[H])=N1
[H]OC(=O)C([H])([H])C([H])([H])C([H])([H])OC([H])([H])C([H])([H])C1([H])C([H])([H])C([H])([H])N(C(=O)[C@]([H])(N([H])S(=O)(=O)C2=C3N([H])C([H])([H])[C@]([H])(C([H])([H])[H])C([H])([H])C3=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C([H])([H])N=C(N([H])[H])N([H])[H])C([H])([H])C1([H])[H]
[H]N(C(=O)[C@]1([H])SC([H])([H])C([H])([H])N1S(=O)(=O)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H])[C@@]1([H])[C@@]2([H])C([H])([H])[C@]3([H])C([H])([H])[C@]([H])(C2([H])[H])C([H])([H])[C@@]1([H])C3([H])[H]
[H]N([H])C1=C(N([H])C2=C3C([H])=C(N([H])C(=O)C([H])([H])C([H])([H])N4C([H])([H])C([H])([H])C([H])([H])C4([H])[H])C([H])=C([H])C3=NC3=C2C([H])=C([H])C(N([H])C(=O)C([H])([H])C([H])([H])N2C([H])([H])C([H])([H])C([H])([H])C2([H])[H])=C3[H])C([H])=C([H])C([H])=C1[H]
CN(C)C(=O)CCC1=C(C=CC=C1)C1=CC(C)=C(C=C1)C(CN)CC1=CC=C(OCCOC2=C(Cl)C=C(C)C=C2Cl)C=C1
[H]C1=C([H])C([H])=C([H])C(=N1)C([H])([H])C([H])([H])N1C([H])([H])C2=C(C3=C([H])C([H])=C([H])C([H])=C3N2C([H])([H])C([H])([H])C([H])([H])N2C([H])([H])C([H])([H])N(C3=C([H])C([H])=C([H])C(Cl)=C3[H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]N(C1=C([H])C([H])=C(F)C(Cl)=C1[H])C1=C2C([H])=C(N([H])C([H])([H])C3=C(N([H])C(=N3)C([H])([H])C([H])([H])[H])C([H])([H])[H])C([H])=C(Cl)C2=NC([H])=C1C#N
[H]N(C(=O)C1=C([H])C2=C(O1)C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C([H])C([H])=C(Cl)C([H])=C2Cl)C([H])([H])C1([H])[H]
[H]OC1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)\N=C(/N([H])[C@]([H])(C(=O)N([H])[H])C([H])([H])[H])N1N=C(C2=C([H])C([H])=C(Cl)C([H])=C2[H])[C@@]([H])(C2=C([H])C([H])=C([H])C([H])=C2[H])C1([H])[H]
[H]C1=C([H])C(=C([H])C([H])=C1Cl)C([H])([H])C(=O)N1[C@@]2([H])C(=O)N3C([H])([H])C([H])([H])C4=C(C(OC([H])([H])[H])=C([H])C(OC([H])([H])[H])=C4[H])[C@]3([H])[C@]1([H])C([H])([H])C([H])([H])C2([H])[H]
[H]ON([H])C(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C(=O)N([H])C1=C([H])C(=C([H])C([H])=C1[H])C1=C([H])N(N=N1)C([H])([H])C1=C([H])C([H])=C(O[H])C([H])=C1[H]
[H]N1C(=S)N([H])C(=O)C(=C([H])C2=C([H])C([H])=C(C([H])=C2[H])N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H])C1=O
[H]O[C@@]1([H])C(=O)OC([H])([H])[C@@]23C([H])([H])C([H])([H])[C@]4(O[C@@]4([H])[C@]2([H])O[C@]2([H])C([H])([H])[C@@]([H])(OC(=O)\C([H])=C(/[H])\C(\[H])=C([H])\C(=O)OC([H])([H])C([H])([H])[C@@]1([H])C([H])([H])[H])[C@@]3(C([H])([H])[H])[C@]21OC1([H])[H])C([H])([H])[H]
[H]N1C([H])=NC(=C1[H])C([H])([H])C1=C([H])SC([H])=C1C([H])([H])C([H])([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])[N+](C([H])([H])[H])(C([H])([H])[H])[C@@]([H])(C([H])([H])[H])C([H])([H])[C@]1([H])C([H])=C([H])C([H])=C([H])C1([H])[H]
[H]C1=C([H])C2=C(C([H])=C1[H])N(C1=C(S2)C([H])=C([H])C(OC([H])([H])[H])=C1[H])C([H])([H])[C@@]([H])(C([H])([H])[H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)C([H])([H])[C@@]1([H])S[C@@]([H])(N(C1=O)C([H])([H])C(=O)N([H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C(Cl)C([H])=C1Cl)C([H])([H])C1=C([H])C([H])=C([H])C2=C1C([H])=C([H])C([H])=C2[H]
[H]N([H])C1=C(SC2=C([H])C([H])=C(OC([H])([H])C([H])([H])F)C([H])=C2C([H])([H])N(C([H])([H])[H])C([H])([H])[H])C([H])=C([H])C(Cl)=C1[H]
[H]N=C(N(C1=C([H])C([H])=C([H])C(=C1[H])C([H])([H])C([H])([H])[H])C([H])([H])[H])N(C1=C(Cl)C([H])=C([H])C(=C1[H])C([H])([H])C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)OC([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])[C@]([H])(C(=O)N([H])[C@]([H])(C#N)C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])C(=C([H])C([H])=C1Cl)N1C(=NC(C2=NN=C(O2)C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])=C1C([H])([H])C([H])([H])[H])C1=C([H])C([H])=C(Cl)C([H])=C1Cl
[H]N([H])N1C(=O)C2=C(N=C1C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C3=NC4=C([H])C([H])=C([H])C([H])=C4C([H])=C3[H])C([H])([H])C1([H])[H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H]
[H]N(C(=O)C(=O)[C@@]([H])(N([H])C(=O)C1=C(C([H])=C([H])C(=O)N1[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]N(C([H])([H])C1=C(N=C(O1)C([H])([H])C([H])([H])C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C(C(=C([H])C([H])=C2[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]C1=C([H])C(=C([H])C([H])=C1Cl)[C@]1([H])N(C([H])([H])[H])[C@]([H])(C2=C([H])C([H])=C(Cl)C([H])=C2[H])[C@@]2(C(=O)OC([H])([H])C([H])([H])[H])C(=O)[C@]1(C(=O)OC([H])([H])C([H])([H])[H])C([H])([H])N(C([H])([H])[H])C2([H])[H]
[H]N(N1C2=C([H])C([H])=C(Cl)C([H])=C2N=C(N2C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C2([H])[H])C2=C1C([H])=C([H])C([H])=C2[H])C(=O)C1=C2C([H])=C([H])C([H])=C([H])C2=C([H])C([H])=C1OC([H])([H])C([H])([H])[H]
[H]O[C@@]12C([H])([H])[C@@]3([H])C([H])([H])[C@@]([H])(C1([H])[H])[C@]([H])(N([H])C(=O)[C@@]1(N(C([H])([H])C([H])([H])C1([H])[H])S(=O)(=O)C1=C([H])C([H])=C(C([H])=C1[H])C(=O)C([H])([H])[H])C([H])([H])[H])[C@]([H])(C3([H])[H])C2([H])[H]
[H]N([H])C([H])([H])C([H])([H])C(=O)N([H])[C@@]([H])(C(=O)N1C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])C1(C([H])([H])N([H])C([H])([H])C2=C([H])C([H])=C(C#N)C([H])=C2[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C(Cl)C([H])=C1Cl
[H]OC(=O)[C@@]1([H])N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@]([H])(N([H])C(=O)[C@]([H])(N([H])C(=O)[C@]([H])(N([H])[H])C([H])([H])C2=C([H])C([H])=C(O[H])C([H])=C2[H])C([H])([H])SSC1([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])[C@]([H])(C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])[H])[C@@]([H])(O[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]\C(=C(\[H])[C@]1([H])[C@]2([H])[C@]([H])(OC(=O)[C@]2([H])C([H])([H])[C@]2([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@@]12[H])C([H])([H])[H])C1=C([H])C([H])=C([H])C(=N1)C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C1=C([H])N=C([H])C(=C1[H])C1=C([H])N=C2N([H])C([H])=C(C2=C1[H])C1=C([H])C(C#N)=C([H])C([H])=C1[H])S(=O)(=O)C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C([H])([H])C1=C([H])C(Cl)=C(Cl)C([H])=C1[H])[C@]([H])(C(=O)N1C([H])([H])C([H])([H])C2(C3=C(C([H])=C([H])C([H])=C3[H])N(C2([H])[H])S(=O)(=O)C([H])([H])[H])C([H])([H])C1([H])[H])C([H])([H])OC([H])([H])C1=C([H])C(Cl)=C(Cl)C([H])=C1[H]
[H]OC(=O)C1=C(N([H])C2=C(Cl)C(=C([H])C([H])=C2Cl)C([H])([H])[H])C([H])=C([H])C([H])=C1[H]
[H]C1=NC2=C([H])C([H])=C(C([H])=C2C([H])=C1[H])C(=O)C1=C(N(C2=C([H])C([H])=C([H])C([H])=C12)C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C([H])([H])[H]
[H]ON([H])C(=O)C1(N([H])S(=O)(=O)C2=C([H])C([H])=C(OC3=C([H])C([H])=C(F)C([H])=C3[H])C([H])=C2[H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]C1=C2C(=C([H])C(=C1[H])C(=O)OC([H])([H])[H])S(=O)(=O)N=[S@]2C1=C([H])C([H])=C(Br)C([H])=C1[H]
[H]C1=C([H])C(=C(F)C([H])=C1Cl)C([H])([H])N1C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C1([H])[H])[C@@]1([H])[C@@]2([H])C([H])([H])[C@]3([H])C([H])([H])[C@@]([H])(C([H])([H])[C@@]1([H])C3([H])[H])C2([H])[H]
[H]C1=C(OC([H])([H])[H])C(OC([H])([H])[H])=C([H])C(=C1[H])C([H])([H])C1=[N+](C([H])([H])[H])C([H])([H])C([H])([H])C2=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C([H])=C12
[H]N(C1=C([H])C([H])=C([H])C(=N1)C1=C([H])N=C2C([H])=C([H])C(Cl)=C([H])N12)C1([H])C([H])([H])C([H])([H])N([H])C([H])([H])C1([H])[H]
[H]OC(=O)C([H])([H])N1C(SC([H])([H])C2=C([H])C([H])=C([H])C(OC([H])([H])[H])=C2[H])=NC2=C([H])C([H])=C([H])C([H])=C12
[H]O[C@@]1([H])C2=C(C([H])=C3C([H])([H])C([H])([H])[C@@](O[H])(C([H])([H])C([H])([H])C4=C([H])C([H])=C([H])C([H])=C4C(=O)N([H])C([H])([H])C([H])([H])[H])[C@@]13C([H])([H])[H])N(N=C2[H])C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]N(C(=O)[C@@]1([H])N([H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2C1([H])[H])[C@@]([H])(C(=O)N1C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])[C@]1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])N1N=C([H])N=C1[H])C([H])([H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
CS(=O)(=O)NC1=C2N=C(C=C(O)C2=CC=C1)C(=O)NC1=CC=CC=C1Cl
[H]SC1=NN=C(S1)N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])S(=O)(=O)C1=C(Cl)C([H])=C([H])C(Cl)=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H]
[H]N(N(C([H])([H])[H])C([H])([H])[H])C(=O)N([H])C1=C2C(=O)C3=C(N([H])N=C3C2=C([H])C([H])=C1[H])C1=C([H])SC([H])=C1[H]
[H]OC1=C([H])C([H])=C2OC([H])([H])[C@]([H])(N(C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C2=C1[H]
[H]N(C(=O)[C@@]([H])(C1=C([H])C([H])=C(N([H])S(=O)(=O)C([H])([H])[H])C([H])=C1[H])C([H])([H])[H])C([H])([H])[C@]([H])(C([H])([H])OC(=O)C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(C(=C1[H])C([H])([H])[H])C([H])([H])[H]
[H]N1C([H])([H])C([H])([H])[C@@]([H])(N(C([H])([H])C2=C([H])C3=C([H])C([H])=C([H])C([H])=C3C([H])=C2[H])S(=O)(=O)C([H])([H])[H])C1([H])[H]
[H]N(C(=O)OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])N([H])C(=O)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1C([H])([H])C([H])([H])N(C([H])([H])C(=O)N2C3=C(N([H])C(=O)C4=C2C([H])=C([H])C([H])=C4[H])C([H])=C([H])C([H])=N3)C([H])([H])C1([H])[H]
[H]N([H])C1=NC2=C([H])C(C3=C4C([H])=C([H])C([H])=C([H])C4=C([H])C([H])=C3OC([H])([H])C([H])([H])[H])=C(C([H])=C2C(=N1)N([H])[H])C([H])([H])[H]
[H]N1C([H])([H])[C@]2([H])[C@@]([H])(C3=C([H])C([H])=C([H])C([H])=C3[H])[C@]2(C2=C([H])C([H])=C(Cl)C(Cl)=C2[H])C1([H])[H]