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[H]N(C(=O)C1=NC(=NC2=C([H])C([H])=C([H])C([H])=C12)C1=C([H])C([H])=C([H])C([H])=C1[H])[C@@]([H])(C(=O)OC([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)C1=C([H])C([H])=C([H])C([H])=N1)C1=C([H])C(=C([H])C([H])=N1)C1=C([H])C2=C(N1[H])[C@]1(C([H])([H])N([H])C2=O)C([H])([H])N([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(C(=O)C([H])([H])OC1=C(Cl)C([H])=C(Cl)C([H])=C1[H])C1=C([H])C([H])=C2N=C(C([H])=C(C2=C1[H])C([H])([H])[H])N(C([H])([H])[H])C([H])([H])C([H])([H])OC(=O)C([H])([H])[H]
[H]N1C(=O)C([H])=C(OC(=O)C2=C([H])C([H])=C(C([H])=C2[H])S(=O)(=O)N(C([H])([H])[H])C([H])([H])[H])C2=C([H])C([H])=C([H])C([H])=C12
[H]N1C2=C([H])C([H])=C(C([H])=C2C(OC([H])([H])C1=O)(C1=C([H])C([H])=C(Cl)S1)C1=C([H])C([H])=C(Cl)S1)C1=C([H])C(F)=C([H])C(C#N)=C1[H]
[H]OC(=O)C([H])([H])N1C(=S)S\C(=C(\[H])C2=C([H])C([H])=C(O2)C2=C([H])C([H])=C(C([H])=C2[H])S(=O)(=O)N([H])[H])C1=O
[H]N(C(=O)C1=C([H])C([H])=C(Cl)C([H])=C1Cl)C([H])([H])C1(C2=C(F)C([H])=C([H])C([H])=N2)C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])S(=O)(=O)C1=C([H])C([H])=C([H])N=C1[H]
[H]N(C1=NC2=C(S1)C([H])([H])C([H])([H])C([H])([H])C1=C2C([H])=C(F)C([H])=C1[H])C([H])([H])C1([H])C([H])([H])C([H])([H])N(C(=O)C([H])([H])N([H])C([H])([H])C([H])([H])C([H])([H])OC([H])([H])[H])C([H])([H])C1([H])[H]
[H]OC1=C([H])C(=C2OC([H])([H])C(=O)N([H])C2=C1[H])[C@]([H])(O[H])C([H])([H])N([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(Br)C([H])=C1[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1=C(SC2=C1C(=O)N(C(=O)N2C([H])([H])C1=C(F)C([H])=C([H])C([H])=C1F)C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]N1C(=O)C([H])([H])C(=NC([H])([H])[C@]11C([H])([H])[N@]2C([H])([H])C([H])([H])[C@]1([H])C([H])([H])C2([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC(=O)[C@@]([H])(N([H])C(=O)C1=C([H])C([H])=C([H])C([H])=C1Br)C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C1=NC(F)=C([H])C2=C1C1(OC2([H])[H])C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C(C([H])=C2[H])C(=O)C2=C([H])C([H])=C(F)C(F)=C2[H])C([H])([H])C1([H])[H]
[H]N(C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C1=NC2=C([H])C([H])=C(F)C([H])=C2C(C([O-])=O)=C1C([H])([H])[H]
[H]N([H])S(=O)(=O)C1=C([H])C([H])=C(C([H])=C1[H])C1=C(C(=O)C([H])=C(O1)C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
CCCCN(C(=O)C1=CC=C(Cl)C=C1)C1=NN=C(S1)C1=CC(F)=CC=C1
[H]O[C@]1([H])N(C(=N[H])N([H])[H])C([H])([H])C([H])([H])C([H])([H])[C@]1([H])N([H])C(=O)[C@@]1([H])N2C(=O)[C@@]([H])(N([H])S(=O)(=O)C3=C([H])C([H])=C([H])C4=C3N([H])C([H])([H])[C@]([H])(C([H])([H])[H])C4([H])[H])C([H])([H])C([H])([H])C([H])([H])[C@@]2([H])C([H])([H])C1([H])[H]
[H]ON([H])C(=O)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1C2=C([H])C([H])=C([H])C([H])=C2C2=C1C([H])([H])C([H])([H])N(C2([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N1C(=N[C@](C2=C([H])C([H])=C(F)N=C2[H])(C2=C([H])C([H])=C(F)C([H])=C2[H])[C@]1([H])C([H])([H])[H])C1=C([H])C([H])=C(C(=O)N1[H])C([H])([H])[H]
[H]N(C(=O)C1=C(Cl)C([H])=C([H])C([H])=C1[H])C([H])([H])C1(C2=C([H])C([H])=C([H])C(=N2)C([H])([H])[H])C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])S(=O)(=O)C([H])([H])C([H])([H])C([H])([H])[H]
CCCCCCCCC(NC(=O)[C@@H]1CCCN1C(=O)[C@H](CC1=CC=CC=C1)NC(=O)OCC1=CC=CC=C1)B1O[C@@H]2CC3CC(C3(C)C)[C@]2(C)O1
[H]OC(=O)C([H])([H])[C@@]([H])(N([H])C(=O)C1=C(N([H])C(=O)OC([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])=C(Cl)C([H])=C1[H])C(=O)C([H])([H])F
[H]N([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@]([H])(N([H])C(=O)[C@@]1([H])N2N(C([H])([H])C1([H])[H])C([H])([H])C([H])([H])[C@](N([H])[H])(C2=O)C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C(=O)C(=O)N([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N1C([H])([H])C(C(=O)N(C([H])([H])C2=C(Cl)C(Cl)=C([H])C([H])=C2[H])C2([H])C([H])([H])C2([H])[H])=C(C2=C([H])C([H])=C(C([H])=C2[H])C([H])([H])C([H])([H])C([H])([H])OC2=C(F)C([H])=C([H])C(F)=C2Cl)C(C([H])([H])[H])(C([H])([H])[H])C1([H])[H]
[H]OC(=O)C([H])([H])OC1=C(C([H])=C(OC([H])([H])C([H])([H])C([H])([H])OC2=C(C([H])=C(N=C2[H])C(F)(F)F)C([H])([H])C([H])([H])C([H])([H])[H])C([H])=C1[H])C([H])([H])[H]
[H]C1=NC([H])=C(N1C([H])([H])C1=C([H])C2=C(C([H])=C1[H])N(C(=O)C([H])=C2C1=C([H])C(Cl)=C([H])C([H])=C1[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(C#N)C([H])=C1[H]
[H]OC1=C([H])C([H])=C(C([H])=C1[H])N1N=C2N(C1=O)C1=C(N=C([H])C([H])=C1[H])N([H])C2=O
[H]OC(=O)C([H])([H])[C@]([H])(N([H])C(=O)C([H])([H])N(C(=O)C([H])([H])C([H])([H])C([H])([H])C1([H])C([H])([H])C([H])([H])N([H])C([H])([H])C1([H])[H])C([H])([H])C([H])([H])[H])C(=O)N([H])[C@]([H])(C(=O)O[H])C([H])([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]N=C(N([H])[H])N([H])OC([H])([H])C([H])([H])N([H])C(=O)C([H])([H])C1=C(F)C(N([H])C([H])([H])C(F)(F)C2=C([H])C([H])=C([H])N=C2[H])=C([H])C([H])=C1Cl
[H]C([H])=C([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])OC([H])([H])C([H])([H])OC([H])([H])C([H])([H])OC([H])([H])C([H])([H])OC([H])([H])C([H])([H])N1C([H])=NC2=C1C(=O)N(C(=O)N2C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])C(=C([H])C([H])=C1N(C([H])([H])[H])C([H])([H])C([H])([H])[H])[C@@]1([H])OC2=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C([H])=C2C(=O)C1([H])[H]
[H]N1C([H])([H])C(=C([H])C([H])([H])C1([H])[H])C(=O)OC([H])([H])[H]
[H]OC(=O)[C@]1([H])[C@@]([H])(SC([H])([H])C([H])([H])C2=C([H])C([H])=C(C([H])=C2[H])C2=C([H])C([H])=C(Cl)C([H])=C2[H])C([H])([H])C([H])([H])[C@@]1([H])C([H])([H])N1C(=O)C2=C(C([H])=C([H])C([H])=C2[H])C1=O
[H]OC(=O)[C@@]([H])(N([H])S(=O)(=O)C1=C([H])N=C([H])C([H])=C1[H])C([H])([H])N([H])C(=O)C1=C([H])C2=C(S1)C([H])=C(S2)C([H])([H])C([H])([H])C1([H])C([H])([H])C([H])([H])N([H])C([H])([H])C1([H])[H]
[H]OC([H])([H])[C@@]1([H])O[C@@]([H])(N2C([H])=NC3=C2N=C(OC2=C([H])C([H])=C([H])C([H])=C2[H])N=C3N([H])[H])[C@]([H])(O[H])[C@]1([H])O[H]
[H]OC(=O)[C@@]1([H])N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@]([H])(N([H])C(=O)[C@]([H])(N([H])C(=O)[C@]([H])(N([H])C(=O)N([H])[H])C([H])([H])C2=C([H])C([H])=C(O[H])C([H])=C2[H])C([H])([H])SSC1([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])[C@@]([H])(C1=C([H])C([H])=C(N([H])C([H])([H])[H])C([H])=C1[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])[H])[C@]([H])(O[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(\N=C(/C1=C([H])C([H])=C([H])S1)C([H])([H])[H])C1=NC(=C([H])S1)C1=C(F)C([H])=C(F)C([H])=C1[H]
[H]OC(=O)[C@@]([H])(N([H])C(=O)C1(C([H])([H])C#N)C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C(N([H])C(=O)C2=C(Cl)C([H])=C([H])C([H])=C2Cl)C([H])=C1[H]
[H]N([H])C(=N/C([H])([H])C([H])([H])C([H])([H])[C@]([H])(N([H])[H])C([H])([H])N([H])C1=C([H])C([H])=C(N([H])[H])C([H])=C1[H])\N([H])[N+]([O-])=O
[H]OC(=O)[C@]([H])(N([H])C(=O)C1=C([H])C([H])=C(N([H])C([H])([H])C2=NC3=C(N=C(N=C3N=C2[H])N([H])[H])N([H])[H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=O)C1=C([H])C([H])=C(Cl)C(Cl)=C1[H]
[H]N(C1=C([H])C([H])=C2C([H])=C([H])C([H])=C([H])C2=C1[H])C([H])([H])N1C(=O)C(=O)C2=C1C([H])=C([H])C([H])=C2[H]
[H]N(C1=C([H])C2=C(N([H])C(=C2[H])C(=O)N2C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C2([H])[H])C([H])=C1[H])[C@]([H])(C([H])([H])[H])C([H])([H])N(C([H])([H])[H])C([H])([H])C([H])([H])N(C1=NC([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]N1N=NC(=N1)C1=C([H])C([H])=C([H])C([H])=C1C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1C(=O)N(N=C1C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])[N+]([O-])=O
[H]N([H])C([H])([H])[C@]1([H])C([H])([H])[C@@]1(C(=O)N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H])C1=C([H])C([H])=C(Cl)S1
[H]C1=C([H])C([H])=C(C(OC([H])([H])[H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NN=C(N1C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])C([H])([H])[H]
CC1=CC(NC(=O)NCCCC[C@@H](NC2=CC(C)=C(F)C(C)=C2)C(=O)NO)=CC=C1F
[H]C1=NN(C([H])=C1C([H])([H])N1C([H])([H])C([H])([H])N(C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]C1=NC([H])=C2N1C([H])([H])C1=C([H])C([H])=C(C#N)C(OC3=C([H])C([H])=C(Cl)C(=C3[H])C([H])([H])N3C(=O)C([H])([H])[N@@](C([H])([H])C3([H])[H])C2([H])[H])=C1[H]
[H]N(C(=O)C1=C([H])C2=C(C([H])=C1[H])C([H])([H])[C@]1([H])N(C([H])([H])C3([H])C([H])([H])C3([H])[H])C([H])([H])C([H])([H])[C@@]2(C([H])([H])[H])[C@@]1([H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
S(C1=CC=CC=C1)C1=NN2C(C=C1)=NN=C2C1=CN=CS1
[H]N(C1=C([H])C(=C([H])C([H])=C1[H])C([H])([H])[H])C1=C2C(=NC(=C2C([H])([H])[H])C([H])([H])[H])N=C([H])N1[H]
[H]C1=C([H])C(OC([H])([H])[H])=C2C(SC3=C2C([H])=C([H])N(C3=O)C2=C([H])C([H])=C([H])C(OC([H])([H])[H])=C2[H])=N1
[H]N(C1=C2C([H])=NN(C2=NC([H])=N1)C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C(Cl)=C1[H]
[H]N([H])S(=O)(=O)OC1=C([H])C(=C([H])C(OS(=O)(=O)N([H])[H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]OC1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[C@]([H])(N([H])[H])C(=O)N([H])[C@@]1([H])C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[H])C([H])([H])C(=O)N([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]\C(=C(\[H])[C@@]1([H])C2=C(C([H])=C([H])C([H])=C2[H])C([H])([H])[C@]2([H])C(=O)OC([H])([H])[C@]12[H])C1=C([H])C([H])=C(C([H])=N1)C1=C([H])C([H])=C([H])C(F)=C1[H]
[H]C1=NC([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])O[C@]1([H])O[C@]([H])(C2=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C(OC([H])([H])[H])=C2[H])C([H])([H])C1([H])[H]
[H]C1=C([H])C(C2=C3N(N=C2C2=C([H])C([H])=C(F)C([H])=N2)C([H])([H])C([H])([H])C3([H])[H])=C2C([H])=C([H])C([H])=C([H])C2=N1
[H]N(C(=O)C1=C(OC([H])([H])[H])C(OC([H])([H])[H])=C([H])C([H])=C1[H])C1=C([H])C2=C(C([H])=C1[H])N(C1=C([H])C([H])=C([H])C([H])=C21)C([H])([H])C([H])([H])[H]
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[H]N1C2=C(C(=O)C([H])([H])C([H])([H])[C@]2(C([H])([H])[H])[C@@]2([H])C([H])([H])C([H])([H])[C@]3(C([H])([H])[H])[C@@]([H])(C(=O)N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[C@@]3([H])[C@]2([H])C1([H])[H])C([H])([H])C([H])([H])[H]
[H]OP(=O)(O[H])OC1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[C@@]1([H])N([H])C(=O)[C@@]([H])(N([H])C(=O)C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=O)[C@]2([H])N(C(=O)[C@@]([H])(N([H])C(=O)[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])C1=O)C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C(=O)N([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C2([H])[H]
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[H]O[C@@]1(C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])N(C(=O)C2=NN=C([H])N2[H])[C@@]2([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@@]12[H]
[H]OC1=C([H])C2=C(C([H])=C1[H])C1=C(N2[H])C2=C(C3=C(C([H])=C(O[H])C([H])=C3[H])N2O[C@]2([H])O[C@]([H])(C([H])([H])O[H])[C@@]([H])(O[H])[C@]([H])(O[H])[C@@]2([H])O[H])C2=C1C(=O)N(N([H])C([H])([H])C1=C([H])C([H])=NC([H])=C1C([H])([H])O[H])C2=O
[H]O[C@@]([H])(C([H])([H])S[H])C([H])([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])C([H])([H])[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])[C@]2([H])C([H])([H])[C@@]1([H])[C@@]13C(=O)N(C(=O)[C@@]21[C@@]1([H])C([H])=C([H])[C@]3([H])C1([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=NC([H])=C([H])C([H])=N2)C([H])([H])C1([H])[H]
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[H]OC([H])([H])[C@@]([H])(N([H])C1=C([H])C(=NC(OC2=C(C([H])=C(Cl)C([H])=C2C([H])([H])[H])C([H])([H])[H])=C1C(=O)N([H])C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])[H]
[H]C1=C([H])C(F)=C2N(C(=O)C(=O)C2=C1[H])C([H])([H])C1=C([H])C([H])=C(Br)C([H])=C1[H]
[H]N(C(=O)C1=C([H])/C2=C(C([H])=C([H])C(=C2[H])C2=C([H])C([H])=C(OC([H])([H])C([H])([H])OC([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])=C2[H])N(C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C\1([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])[S@@+]([O-])C([H])([H])C1=C([H])N=C([H])N1C([H])([H])C([H])([H])C([H])([H])[H]
[H]OC1=NC(=C(C2=C([H])C([H])=C3N=C(N([H])C4=C(Cl)C([H])=C([H])C([H])=C4Cl)N(C3=C12)C([H])([H])[H])C([H])([H])C(=O)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C([H])([H])[H]
[H]C1=C([H])C(=C([H])C([H])=C1Cl)C1=C(C(=NN1C1=C([H])C([H])=C(Cl)C([H])=C1Cl)C1=NN=NN1C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H]
CC(C)C[C@H](CO)NC1=NC(SCC2=C(Cl)C=CC=C2)=NC2=C1SC(N)=N2
CC[C@@H](NC1=NC(NCC2=C(O)C=CC(F)=C2)=C2N=CN(C(C)C)C2=N1)C(C)O
[H]OC1=C([H])C([H])=C([H])C(=C1[H])C([H])([H])[C@@](O[H])(C(=O)N([H])C1=C([H])C2=C(C([H])=C1[H])C(=O)OC2([H])[H])C([H])([H])C(C1=C([H])C([H])=C([H])C([H])=C1[H])(C([H])([H])[H])C([H])([H])[H]
[H]OC([H])([H])C([H])([H])C1=C([H])C([H])=C(N([H])C(=O)C2=C([H])C3=C([H])C(Cl)=C([H])C([H])=C3N2[H])C([H])=C1[H]
[H]C1=C2N(C(=NC2=C([H])C(=C1[H])C(=O)N(C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(OC([H])([H])C([H])([H])[H])C([H])=C1[H])C([H])([H])C1([H])C([H])([H])C1([H])[H]
[H]OC(=O)[C@@]1([H])C([H])([H])N(C(=O)[C@@]1([H])N([H])C(=O)C1=C([H])C2=C(C([H])=C([H])C([H])=C2[H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C1=C(Cl)C(=C([H])C(Cl)=C1S(=O)(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C(=O)C([H])([H])C([H])([H])[N@]1C([H])([H])[C@]1([H])C([H])([H])[H]
[H]N(C1=C2C(=NC(=N1)C([H])([H])[H])N(N=C2C([H])([H])[H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1C([H])([H])[H])C([H])(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H]
[H]C1=C2OC3=C(C([H])=C(C([H])=C3OC(=O)C([H])([H])[H])C([H])([H])[H])C([H])([H])OC(=O)C2=C(OC([H])([H])[H])C(=C1[H])[C@@]([H])(OC(=O)C([H])([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]OC1=C([H])C([H])=C(N([H])C(=O)C2=C([H])C([H])=C(OC([H])([H])[H])C([H])=C2[H])C(N([H])C(=O)C2=C([H])C([H])=C(C([H])=C2[H])N2C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C([H])([H])C2([H])[H])=C1[H]
[H]N(C(=O)C1=C([H])N(C2=C(C([H])=C([H])C([H])=C2[H])C1=O)C([H])([H])[H])C1=C([H])C([H])=C(C2=C([H])C([H])=C([H])C([H])=C2[H])C(=N1)C(F)(F)F
[H]N(C1=C(N=C2C([H])=C([H])C([H])=C([H])C2=N1)N([H])S(=O)(=O)C1=C([H])C([H])=C(F)C([H])=C1[H])C1=C([H])C(OC([H])([H])[H])=C([H])C(OC([H])([H])[H])=C1[H]
[H]OC1=C([H])C(=C(C(=C1[H])C([H])([H])[H])C([H])([H])[C@]([H])(N(C([H])([H])[H])C([H])([H])[H])C(=O)N1C([H])([H])C2=C(C([H])=C([H])C([H])=C2[H])C([H])([H])[C@@]1([H])C(=O)N([H])[H])C([H])([H])[H]
[H]N(C(=O)C1=C(N=C(N1C([H])([H])C1=C([H])C(=C(C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1S(=O)(=O)N([H])C1=C(C(=NO1)C([H])([H])[H])C([H])([H])[H])C([H])([H])OC([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H])C([H])([H])[H]
[H]OC(C1=C([H])C([H])=C(C([H])=C1[H])C1=C(ON=C1C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])N([H])[H])(C(F)(F)F)C(F)(F)F
[H]N(C1=NC2=C(C([H])=N1)C([H])=C(C(=O)N2C([H])([H])[H])C1=C(Cl)C([H])=C([H])C([H])=C1Cl)C1=C([H])C(OC([H])([H])[H])=C([H])C([H])=C1[H]
[H]N1C([H])=C([H])N=C1C1=C([H])C([H])=C([H])C([H])=C1C(=O)C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]N(C(=O)C([H])([H])[H])C1=NN([H])C2=NC([H])=C(C([H])=C12)C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N([H])C(=O)C([H])([H])OC1=C([H])C(=C(N([H])C(=O)C2=C([H])C([H])=C(O2)C2=C([H])C(Cl)=C([H])C([H])=C2Cl)C(=C1[H])C([H])([H])[H])C([H])([H])[H]
[H]OC1=C([H])C(=C2C([H])=C3C(N([H])C(C([H])=C3C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])=C([H])C2=N1)C([H])([H])[H]
[H]O[C@](C1=C([H])C([H])=C([H])C([H])=C1[H])(C([H])([H])C(=O)C(\[H])=C(\[H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])C(F)(F)F
[H]O[C@@]1(C#CC2=C([H])C([H])=C(OC3=C([H])C([H])=C(C([H])=C3[H])C(=O)N([H])[C@@]3([H])C([H])([H])C([H])([H])C([H])([H])S(=O)(=O)C3([H])[H])C([H])=C2[H])C([H])([H])[N@]2C([H])([H])C([H])([H])[C@]1([H])C([H])([H])C2([H])[H]
[H]N(C(=O)C1=C([H])C2=C(N1[H])C([H])=C([H])C(Cl)=C2[H])[C@@]1([H])C(=O)N(C2=C(C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H])C([H])([H])[H]
[H]N(C(=O)C1=C([H])C(Cl)=C([H])C(Cl)=C1[H])C([H])([H])[C@]([H])(C1=C([H])C([H])=C([H])O1)[N+]([H])(C([H])([H])[H])C([H])([H])[H]
[H]O[C@@](C1=C([H])C2=C(O1)C([H])=C(OC([H])([H])[H])C([H])=C2[H])(C1=C([H])C([H])=C([H])N=C1[H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]C1=C([H])C([H])=C(N2C(=O)C3=C([H])C([H])=C([H])C([H])=C3C(C2=O)(C([H])([H])[H])C([H])([H])[H])C(Cl)=C1[H]
[H]OC(=O)C1=C([H])SC(SC([H])([H])C([H])([H])N2C(=O)C([H])([H])C([H])([H])[C@]2([H])C(\[H])=C(/[H])[C@@]([H])(O[H])C([H])([H])C2=C([H])C([H])=C([H])C(=C2[H])C([H])([H])[H])=N1
[H]N(C1=NC(=C([H])C([H])=N1)C1=C([H])N=C(N1C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C(=O)N(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)[C@]([H])(N1C([H])([H])C([H])([H])C2=C(C([H])=C(OC([H])([H])[H])C(OC([H])([H])[H])=C2[H])[C@]1([H])C([H])([H])C1=C([H])C([H])=C(OC([H])([H])[H])C(OC([H])([H])[H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]N1C(=C([H])C2=C([H])C([H])=C([H])C([H])=C12)C(=O)N1C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C1([H])[H])S(=O)(=O)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H]
[H]OC1=C([H])\C(=N\C2=C3C([H])=C(OC([H])([H])[H])C(OC([H])([H])C([H])([H])C([H])([H])N4C([H])([H])C([H])([H])C([H])([H])C4([H])[H])=C([H])C3=NC([H])=N2)C(=O)C([H])=C1O[C@]([H])(C#C[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N([H])[C@@]([H])(C([H])([H])[H])C([H])([H])C1=C(OC([H])([H])[H])C([H])=C(C(OC([H])([H])[H])=C1[H])C([H])([H])C([H])([H])[H]
[H]C1=NC(=C([H])C([H])=C1C#N)N1C([H])([H])C([H])([H])C([H])(C(=O)N2C([H])([H])[C@]([H])(C3=C([H])C([H])=C(Cl)C([H])=C3[H])[C@@](C([H])([H])[H])(C([H])([H])OC3=NC([H])=C(Cl)C([H])=C3[H])C2([H])[H])C([H])([H])C1([H])[H]
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[H]N([H])C([H])([H])C1=C(F)C([H])=C([H])C(=C1[H])C1=C([H])C(=NC(OC([H])([H])[H])=N1)N([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]N(C(=O)C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C(C([H])=N1)C(F)(F)F)C1=C([H])N2C(=NC(=C2C([H])([H])[H])C2([H])C([H])([H])C2([H])[H])C([H])=C1[H]
[H]N(C(=O)N([H])C([H])([H])[C@]([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])[C@@]([H])(C(=O)N(C([H])(C([H])([H])[H])C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])C1=C([H])N=C([H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1F
[H]N(C(=O)C([H])([H])C1=C([H])C([H])=C(N([H])C2=NC([H])=NC3=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C([H])=C23)C([H])=C1[H])C1=C([H])N(N=C1[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N([H])C1=C([H])N=C(N(C1=O)C([H])([H])C(=O)N([H])[C@]([H])(C(=O)C1=NN=C(O1)C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])(C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]OC(=O)C([H])([H])C([H])([H])C([H])([H])N([H])C1=C(C#N)C(=NC2=C([H])C([H])=C(F)C([H])=C12)C1=C([H])C(=C(C([H])=C1[H])C1=C(OC([H])([H])C([H])([H])[H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H]
[H]N1C(=O)[C@]([H])(N(C(=O)[C@@]1([H])C1([H])C([H])([H])C2=C(C([H])=C([H])C([H])=C2[H])C1([H])[H])[C@@]([H])(C(=O)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C1=C([H])C([H])=C(OC([H])([H])[H])N=C1[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H]
FC(F)(F)COC1=NC=CC=C1CNC(=O)C1=CC(=CN=C1)C1=CC=C(Cl)C=C1
[H]N(C(=O)C([H])([H])[H])C1=C(C#N)C2=NC3=C([H])C([H])=C([H])C([H])=C3N=C2N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]N([H])C(=O)C1=C2N([H])C3=C(C([H])=C([H])C(=C3[H])C3=C([H])C([H])=C(N=N3)N([H])[H])C2=C(N([H])[C@@]([H])(C([H])([H])[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])=C1[H]
[H]N(C(=O)C1=C([H])C([H])=C(OC([H])([H])C([H])([H])C([H])([H])C([H])([H])N2C3=C(C([H])=C([H])C([H])=C3[H])C3=C2C([H])=C([H])C([H])=C3[H])C([H])=C1[H])C([H])([H])C([H])([H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H]
[H]N(C(=O)[C@@]1([H])C2=C(OC([H])([H])C3=C1C([H])=C([H])C([H])=C3[H])C([H])=C(C(=C2[H])C([H])([H])[H])C([H])([H])[H])C1=C(C([H])=C([H])C([H])=C1C([H])(C([H])([H])[H])C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N([H])[C@@]([H])(C([H])([H])C(=O)N1C([H])([H])C2=NN=C(N2C([H])([H])C1([H])[H])C(F)(F)F)C([H])([H])C1=C(C([H])=C([H])C([H])=C1[H])C(F)(F)F
CCCC1=C(C(=O)OCC)C(C(=O)OCC)=C2N1N=C(C=C2C1=C(F)C=CC=C1)N1CCOCC1
[H]OC1(C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])N(C(=O)C2=C(OC(=N2)C2=C3C([H])=C([H])C(=NC3=C(OC([H])([H])[H])C([H])=C2[H])C(F)(F)F)C([H])([H])N([H])[H])C([H])([H])C1([H])[H]
[H]N(C(=O)C([H])([H])C1=C(N=C(N1C([H])([H])C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C(Cl)=C1C([H])([H])[H]
[H]N([H])C1=C2N=C(C3=C([H])C([H])=C(N([H])C(=O)N([H])C4=C([H])C([H])=C(F)C(=C4[H])C(F)(F)F)C([H])=C3[H])C([H])([H])C([H])([H])N([H])C2=NC([H])=N1
[H]C1=C(N(N=N1)C1=C([H])C([H])=C(Cl)C([H])=C1[H])C1=C([H])C([H])=NC([H])=C1[H]
[H]N(C(=O)C([H])([H])C1=C([H])C([H])=C([H])C(N([H])C([H])([H])C(F)(F)C2=NC([H])=C([H])C([H])=C2[H])=[N+]1[O-])C([H])([H])C1=C([H])C(Cl)=C([H])C([H])=C1N1N=NN=C1[H]
[H]OC1=C([H])C2=C(C([H])=C1[H])C1=C(S2)C2=C(C([H])=C([H])C(O[H])=C2[H])N1C([H])([H])C1=C([H])C([H])=C(OC([H])([H])C([H])([H])N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H])C([H])=C1[H]
[H]C([H])([H])N1C(=O)O[C@]2(C1([H])[H])C([H])([H])[N@]1C([H])([H])C([H])([H])[C@]2([H])C([H])([H])C1([H])[H]
[H]C1=C([H])C2=C(C([H])=C1[H])N(C(=O)O2)C1([H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])C([H])([H])N2C(=O)C3=C(C([H])=C([H])C(F)=C3[H])S2(=O)=O)C([H])([H])C1([H])[H]
[H]N1C2=C(C([H])=C(C([H])=C2[H])C(=O)C([H])([H])C([H])([H])C2([H])C([H])([H])C([H])([H])N(C([H])([H])C3=C([H])C(OC([H])([H])[H])=C([H])C([H])=C3[H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]OC(=O)C([H])([H])[C@]1([H])N([H])C2=C([H])C([H])=C(C([H])=C2C([H])([H])N(C1=O)C([H])([H])C([H])([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C(=O)N([H])C([H])([H])C1=NC2=C(N1[H])C([H])=C([H])C([H])=C2[H]
CC(C)S(=O)(=O)N1CCN([C@@H](CC2CCCCC2)C(=O)NC2=NC=CS2)C(=O)C1
[H]C1=NC([H])=C2N1[C@@]([H])(C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])S(=O)(=O)N(C2([H])[H])[C@]([H])(C1=C([H])C([H])=C(Cl)C([H])=C1[H])C([H])([H])[H]
[H]C1=C([H])C(Cl)=C(C([H])=C1[H])C([H])(N1[C@@]2([H])C([H])([H])C([H])([H])[C@]1([H])C([H])([H])[C@@]([H])(C1=NC(F)=C([H])C([H])=C1[H])C2([H])[H])C1=C([H])C([H])=C([H])C([H])=C1Cl
[H]N([H])C([H])([H])C([H])([H])C1=C([H])N([H])C(=N1)C([H])([H])C([H])([H])C([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C([H])([H])C([H])([H])C([H])([H])C([H])([H])OC1=NSN=C1OC([H])([H])C([H])([H])[N+](C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]OC1=C2O[C@@]3([H])[C@]([H])(N(C([H])([H])C([H])([H])Cl)C([H])([H])C([H])([H])Cl)C([H])([H])C([H])([H])[C@@]4(O[H])[C@]5([H])N(C([H])([H])C6([H])C([H])([H])C6([H])[H])C([H])([H])C([H])([H])[C@]34C2=C(C([H])=C1[H])C5([H])[H]
[H]OC(=O)[C@]1([H])OC2=C(C(OC([H])([H])C([H])([H])C([H])([H])OC3=C([H])C([H])=C(C4=C([H])N([H])N=N4)C(OC([H])([H])[H])=C3C([H])([H])C([H])([H])C([H])([H])[H])=C([H])C([H])=C2C([H])([H])C1([H])[H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]O[C@]([H])(C([H])([H])OC1=C([H])C([H])=C([H])C2=C1C([H])=C(N2[H])C([H])([H])[H])C([H])([H])N1C([H])([H])C([H])([H])C([H])(C2=C([H])C3=C(S2)C([H])=C([H])C([H])=C3F)C([H])([H])C1([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C(=O)O[C@@]1([H])C([H])([H])[C@]2([H])N([C@@]([H])(C([H])([H])C2([H])[H])[C@@]1([H])C(=O)OC([H])([H])[H])S(=O)(=O)C1=C([H])C([H])=C(C([H])=C1[H])[N+]([O-])=O
[H]N(C(=O)C1=C2N=C(OC2=C([H])C([H])=C1[H])C1=C([H])C([H])=C(F)C([H])=C1[H])C1([H])C([H])([H])[C@]2([H])N(C([H])([H])[H])[C@]([H])(C([H])([H])C([H])([H])C2([H])[H])C1([H])[H]
[H]N(C(=O)C([H])([H])OC1([H])C([H])([H])C([H])([H])N(C(=O)N([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC2=C([H])C(C#N)=C([H])C(=C2O1)C([H])([H])[H]
[H]OC(=O)C1=C([H])C(N([H])C(=O)C2=C([H])C(N([H])C3=NC([H])([H])C([H])([H])C([H])([H])N3[H])=C([H])C([H])=C2[H])=C([H])C([H])=C1C([H])([H])C([H])([H])C(=O)O[H]
[H]N(C(=O)C(OC1=C([H])C([H])=C(C([H])=N1)C(F)(F)F)(C([H])([H])[H])C([H])([H])[H])[C@@]([H])(C([H])([H])[H])[C@]([H])(C1=C([H])C([H])=C([H])C(C#N)=C1[H])C([H])([H])C1=C([H])C([H])=C(OC([H])([H])C([H])([H])F)C([H])=C1[H]
[H]OC(=O)C([H])([H])[C@@]1([H])C([H])([H])C([H])([H])[C@]([H])(C2=C([H])C([H])=C(C([H])=C2[H])C(=O)N([H])C2=NN=C(S2)C([H])([H])C2=C([H])C([H])=C(OC([H])([H])[H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]ON([H])C(=O)C([H])([H])[C@@]1(N(C([H])([H])C([H])([H])C([H])([H])C1([H])[H])[C@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])[H])C([H])([H])S(=O)(=O)C1=C([H])C([H])=C(OC([H])([H])C2=C3C([H])=C([H])C([H])=C([H])C3=NC(=C2[H])C([H])([H])[H])C([H])=C1[H]
[H]C1=C([H])C2=C(C([H])=C1[H])S(=O)(=O)N(C2=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])[C@]([H])(C2=C([H])C([H])=C(Cl)C([H])=C2[H])C1([H])[H]
[H]N(C(=O)C1=C([H])C2=C([H])C(Cl)=C([H])C([H])=C2N1[H])C([H])([H])C(=O)N(C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H]
[H]C1=C([H])N(C(=N1)C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1N1C([H])([H])C([H])([H])N(C(=O)[C@]2([H])C([H])([H])N(C([H])([H])[C@@]2([H])C2=C([H])C([H])=C(Cl)C([H])=C2[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N1C(=NC(=C1C1=C([H])C([H])=NC([H])=C1[H])C1=C([H])C([H])=C(F)C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])[S@](=O)C([H])([H])[H]
[H]C1=C(OC(=C1[H])C1=C(OC([H])([H])[H])C([H])=C([H])C(OC([H])([H])[H])=C1[H])C(=O)N(C1=C(C([H])=C([H])C([H])=C1C([H])([H])[H])C([H])([H])[H])C([H])([H])[H]
[H]OC1=C([H])C(=C([H])C([H])=C1[H])[C@]12C([H])([H])C(=O)\C(=C(/[H])C3=C([H])C(OC([H])([H])[H])=C([H])C([H])=C3[H])[C@]([H])(N(C([H])([H])[H])C([H])([H])C1([H])[H])C2([H])[H]
[H]OC([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C([H])([H])C2=C(C([H])=C(N([H])C(=O)C3=C([H])C(C#CC4=C([H])N=C5C([H])=C([H])C([H])=NN45)=C(C([H])=C3[H])C([H])([H])[H])C([H])=C2[H])C(F)(F)F)C([H])([H])C1([H])[H]
[H]N(C1=C([H])C2=C(C([H])=C1[H])N(C([H])=C2[H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])C1([H])[H])S(=O)(=O)C1=C(Cl)N=C2SC([H])=C([H])N12
[H]N([H])C1=NC2=C(S1)C([H])([H])[C@@]([H])(N([H])C(=O)C([H])([H])N1C(=O)C(N([H])S(=O)(=O)C([H])([H])C([H])([H])C([H])([H])[H])=C([H])C([H])=C1C([H])([H])[H])C([H])([H])C2([H])[H]
[H]N(C(=O)N1N=C(C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])[C@@]([H])(C2=C([H])SC([H])=C2[H])C1([H])[H])C(C1=C([H])C([H])=C([H])C([H])=C1[H])(C([H])([H])[H])C([H])([H])[H]
[H]OC1=C([H])C([H])=C([H])C([H])=C1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])S(F)(=O)=O
[H]N([H])C(=O)C1=C2N=C(N([H])C2=C([H])C([H])=C1[H])C1=C([H])C([H])=C2OC([H])([H])OC2=C1[H]
[H]N(C(=O)C([H])([H])[H])C1=C(C2=NC3=C([H])C([H])=C([H])C([H])=C3S2)C2=C(S1)C([H])([H])N(C([H])([H])C2([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]OC(=O)[C@@]([H])(O[H])C([H])([H])N([H])C(=O)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N(C(=O)N([H])C1=C([H])C(=C([H])C(=C1[H])C(F)(F)F)C(F)(F)F)[C@@]1([H])C([H])([H])C([H])([H])[C@@]([H])(C([H])([H])C1([H])[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])C(=O)N2C(=C1[H])[C@@]1([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])C3=C([H])C([H])=C(F)C([H])=C3[H])C([H])([H])[C@@]([H])(C2([H])[H])C1([H])[H]
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[H]N(C(=O)[C@@](N([H])C(=O)OC([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C(=O)OC([H])([H])[H])(C([H])([H])[H])C([H])([H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H])[C@]([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H]
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[H]OC([H])([H])[C@@]1(OC(=O)\C(=C(\[H])C2=C([H])C(=C([H])C([H])=C2[H])C(F)(F)F)C1([H])[H])C([H])([H])OC(=O)C([H])(C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])N(N=N1)C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1N1C([H])([H])C([H])([H])N(C(=O)[C@]2([H])C([H])([H])N(C([H])([H])[C@@]2([H])C2=C([H])C([H])=C(Cl)C([H])=C2[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N(C(=O)[C@@]([H])(N([H])C(=O)C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C#N
[H]OC(=O)C([H])([H])[C@]1(C2=C([H])C([H])=C([H])C([H])=C2[H])[C@@]2([H])C([H])([H])[C@]3([H])C([H])([H])[C@@]([H])(C([H])([H])[C@@]1([H])C3([H])[H])C2([H])[H]
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[H]N([H])C1=NC([H])=NC2=C1N=C(SC1=C(OC([H])([H])[H])C([H])=C([H])C(OC([H])([H])[H])=C1[H])N2C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]N1C(C(=O)OC([H])([H])C([H])([H])[H])=C(C(C(=O)OC([H])([H])C(=O)N2C3=C([H])C([H])=C([H])C([H])=C3N([H])C(=O)C2([H])[H])=C1C([H])([H])[H])C([H])([H])[H]
[H]OC(C(=O)N1C([H])([H])C([H])([H])N(C2=C([H])C(C3=C(C(=O)N([H])C3=O)C3=C([H])N([H])C4=C3C([H])=C([H])C([H])=C4[H])=C(C([H])=C2[H])C(F)(F)F)C([H])([H])C1([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])C([H])=C(C(=C1[H])C1=NN=C(N1C([H])([H])[H])C1(C2=C([H])C([H])=C(Cl)C([H])=C2[H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])[H]
[H]OC1=C([H])C(O[H])=C2C(=C1[H])\C([H])=C([H])\C([H])([H])C([H])([H])[C@]([H])(O[H])[C@]([H])(O[H])\C([H])=C([H])\C([H])([H])[C@@]([H])(OC2=O)C([H])([H])[H]
[H]OC(=O)C(=C(/[H])C1=C([H])C([H])=C(N1[H])C([H])([H])N1C([H])=NC([H])=C1[H])\C([H])([H])[H]
[H]C1=C([H])C2=C(N=C(O2)N(C([H])([H])[H])C([H])([H])C([H])([H])OC2=C([H])C([H])=C(C([H])=C2[H])C([H])([H])[C@]([H])(SC([H])([H])[H])C(=O)OC([H])([H])[H])C([H])=C1[H]
[H]N([H])C1=NN([H])C2=C1C([H])=C([H])C(=C2[H])C1=C([H])C(=NC(=N1)N([H])C([H])([H])[H])N1C([H])([H])[C@]([H])(OC([H])([H])[C@@]1([H])C([H])([H])[H])C(=O)N([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N([H])C(=O)C1=C(OC([H])([H])[H])C([H])=C([H])C([H])=C1N([H])C1=C([H])C(OC2=C([H])C([H])=C(OC([H])([H])[H])C([H])=C2[H])=NC([H])=C1C(F)(F)F
[H]\C(=C(\[H])[C@@]1([H])N(C(=O)[C@@]1([H])N1C(=O)OC([H])([H])[C@]1([H])C1=C([H])C([H])=C([H])C([H])=C1[H])[C@@]([H])(C(=O)OC([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C1(OC([H])([H])C([H])([H])O1)C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
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[H]OC(=O)[C@]([H])(\N=C(/S[H])N([H])C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)N([H])[H])[C@]([H])(O[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N1\C(SC2=C([H])C([H])=C([H])C([H])=C12)=C(/N=O)C#N
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Cl.[H][C@@]12CCC3=CC=CC=C3[C@]1([H])CCN(CC1=CC=C(C=C1)[N+]([O-])=O)C2
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[H]O[C@]12OC(=O)C(=C1C1=C(C([H])=C([H])C([H])=C1[H])C([H])([H])C2([H])[H])C1=C([H])C([H])=C(SC([H])([H])[H])C([H])=C1[H]
[H]N(C([H])([H])C1=C([H])C([H])=C(S1)C1=C([H])C([H])=C([H])N=C1[H])C([H])([H])C1=C([H])C([H])=C(S1)C1=C([H])C([H])=C([H])N=C1[H]
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[H]C1=C(C([H])=NS1)C1=C([H])N=C2C([H])=C(C([H])=C([H])N12)C1=C([H])C([H])=C([H])C([H])=C1[H]
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[H]OC(=O)C1=C([H])SC(=C1[H])S(=O)(=O)N1C([H])([H])C([H])([H])C([H])(C(=O)N([H])C2([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]N(C(=O)N1C([H])([H])C([H])([H])C([H])(N2C(=O)N([H])C3=C(C([H])=C([H])C([H])=C3[H])C2([H])[H])C([H])([H])C1([H])[H])[C@]1([H])N=C(C2=C([H])C([H])=C([H])C([H])=C2[H])C2=C([H])C([H])=C([H])C([H])=C2N(C1=O)C([H])([H])[H]
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[H]OC1=C([H])C([H])=C([H])C(=C1[H])C(=O)N([H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C3=C([H])C([H])=C([H])C([H])=C3C([H])=C2[H])C([H])([H])C1([H])[H]
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[H]N1C2=C(OC3=C([H])C([H])=C([H])C([H])=C23)C(=O)N(C1=S)C1=C([H])C([H])=C([H])C(=C1[H])C([H])([H])[H]
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[H]C1=NC([H])=C(N1C([H])([H])[H])[C@]([H])(OC([H])([H])C1=C(C([H])=C(C#N)C(=O)N1C([H])([H])[H])C1=C([H])C([H])=C([H])C(F)=C1[H])C1=C([H])C([H])=C(C#N)C([H])=C1[H]
[H]OC(=O)C([H])([H])C([H])([H])C1=C([H])C([H])=C(OC([H])([H])C2=C([H])C([H])=C([H])C(=C2[H])C2=C([H])C([H])=C([H])C([H])=C2Cl)C([H])=C1[H]
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[H]OC([H])([H])[C@]1(OC(=O)\C(=C(\[H])C2=C([H])C([H])=C(C([H])=C2[H])C(F)(F)F)C1([H])[H])C([H])([H])OC(=O)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H]
[H]OC1=C([H])C([H])=C(\C([H])=C2/OC(=O)N(C2=O)C2=C([H])C([H])=C(SC([H])([H])[H])C([H])=C2[H])C([H])=C1Br
[H]N(C(=O)C1=C2C([H])=C([H])C([H])=C([H])C2=NC(C2=C([H])C([H])=C([H])C([H])=C2[H])=C1C([H])([H])N1C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
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[H]C1=NC(=C(N1C([H])([H])C1=C([H])C(C#N)=C([H])C([H])=C1[H])C1=C([H])C([H])=C(F)C([H])=C1[H])C1=C([H])C([H])=NC(OC([H])([H])[H])=N1
[H]N1C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])[C@@]([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])C(=C([H])C([H])=C1[H])C(F)(F)F
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[H]N(C1=C([H])C([H])=C2N([H])N=C(C3=C([H])C4=C(N3[H])C([H])=C(C([H])=C4[H])C([H])([H])[H])C2=C1[H])S(=O)(=O)C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N1C([H])([H])C([H])=C(C2=C([H])N(C3=C2C([H])=C([H])C([H])=C3[H])S(=O)(=O)C2=C([H])C([H])=C([H])C([H])=C2Cl)C([H])([H])C1([H])[H]
[H]N(C1=NC(=NC2=C([H])C([H])=C([H])C([H])=C12)C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC([H])([H])[C@@]1(OC(=O)\C(=C(\[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C1([H])[H])C([H])([H])OC(=O)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H]
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[H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C2(OC3=C(C([H])=C([H])C([H])=C3[H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]OC(=O)C([H])([H])N1C([H])=C([H])C(=O)N(C1=O)C([H])([H])C1=NC2=C(S1)C([H])=C([H])C(Cl)=C2[H]
[H]OC([H])([H])C([H])([H])C1=C([H])C2=C(OC([H])([H])C3=C([H])C([H])=C([H])C([H])=C3\C2=C(/[H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H])C([H])=C1[H]
[H]N([H])C1=C(C(=O)C([H])([H])[H])C(=O)N(C2=C1C([H])=C(C1=C([H])C([H])=C(Cl)C([H])=C1[H])C(=N2)C1=C([H])C([H])=C(Cl)C([H])=C1Cl)C([H])([H])[H]
[H]C1=C([H])C(=C(C([H])=C1C(=O)N1C([H])([H])C([H])([H])[C@]2([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@@]2([H])C1([H])[H])S(=O)(=O)N1C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])N2C(=NC(=C(C2=O)C([H])([H])C([H])([H])N2C([H])([H])C([H])([H])C([H])(C(=O)C3=C([H])C([H])=C(F)C([H])=C3[H])C([H])([H])C2([H])[H])C([H])([H])[H])C([H])=C1[H]
[H]OC(=O)[C@@]([H])(N1C([H])([H])C([H])([H])C([H])(C([H])([H])N2C([H])([H])C([H])([H])C([H])(OC3=C(Cl)C([H])=C(Cl)C([H])=C3[H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]OC(=O)C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])OC1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C([H])S1
[H]C1=C([H])C([H])=C([H])C(=N1)C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1=C(N=C2N1C(=O)C(C1=C([H])C(=C([H])C([H])=C1[H])C(F)(F)F)=C(N2C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1F)C([H])([H])[H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])OC(=O)N1C([H])([H])C([H])([H])N(C(=O)C([H])([H])C2=C([H])C([H])=C(Cl)C(Cl)=C2[H])[C@@]([H])(C([H])([H])N2C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C1([H])[H]
OC(=O)C(F)(F)F.CN(C)CCCCC(=O)N1CCN(CC1)C(=O)C1(CCOCC1)NS(=O)(=O)C1=C(Cl)C(COC2=C3N=C(C)C=C(C)C3=CC=C2)=C(Cl)C=C1
[H]N(C(=O)C([H])([H])C1=C([H])C(=C([H])C(=C1[H])C(F)(F)F)C(F)(F)F)C([H])([H])[C@]([H])(N1C([H])([H])C([H])([H])C([H])(N2C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C1=C(ON=C1C([H])([H])[H])C([H])([H])C(=O)C([H])([H])[C@@]1([H])C([H])([H])C([H])([H])[C@]([H])(C([H])([H])C([H])([H])N2C([H])([H])C([H])([H])N(C3=NC([H])=C([H])C4=C3C([H])([H])C([H])([H])O4)C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]OC(=O)C([H])([H])[C@]([H])(N([H])C(=O)[C@]([H])(N1C([H])=C([H])C([H])=C(N([H])C(=O)C2=C3C([H])=C([H])C([H])=C([H])C3=C([H])C([H])=C2[H])C1=O)C([H])([H])[H])C(=O)C([H])([H])OC1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)C1([H])C([H])([H])C1([H])[H])C1=NC2=C(S1)C(C#N)=C(OC1=C([H])C(N([H])C(=O)N([H])C3=C([H])C([H])=C(C([H])=C3[H])C(F)(F)F)=C(F)C([H])=C1[H])C([H])=C2[H]
[H]C1=NC2=C(N1C([H])([H])C([H])([H])[H])C(=O)N(C(=O)N2C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)C1=C2OC(=NC2=C([H])C([H])=C1[H])C1=C([H])C([H])=C(F)C([H])=C1[H])C1([H])C([H])([H])[C@]2([H])N(C([H])([H])[H])[C@]([H])(C([H])([H])C([H])([H])C2([H])[H])C1([H])[H]
[H]N(C(=O)C(=O)[C@@]([H])(N([H])C(=O)C([H])([H])C([H])([H])C(=O)C1=C([H])C([H])=C([H])C([H])=C1OC([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C1=C([H])C2=C(N(N=C2C(=C1[H])C(F)(F)F)C([H])([H])C1=C([H])C([H])=C(F)C([H])=C1Cl)C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]N(C([H])(C([H])([H])[H])C([H])([H])[H])[C@@]([H])(C([H])([H])N1C(=O)N(C(=C(C1=O)C1=C([H])C([H])=C([H])C(OC([H])([H])[H])=C1F)C([H])([H])[H])C([H])([H])C1=C(F)C([H])=C([H])C([H])=C1F)C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N1C(=O)C2=C([H])C([H])=C([H])C3=C2[C@@]([H])(N(C(=O)C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C3([H])[H])C1([H])[H]
[H]N(C1=C2C(N([H])N=C2S(=O)(=O)C2=C([H])C([H])=C([H])C3=C([H])C([H])=C([H])C([H])=C23)=C([H])C([H])=C1[H])[C@]1([H])C([H])([H])N([H])C([H])([H])C([H])([H])C1([H])[H]
CCNC1=NC(C(N)=O)=C2CN(CCC2=N1)C(=O)CCC1=CC=C(OC)C=C1
[H]OC1=C([H])C([H])=C(OC2=C([H])C([H])=C(C([H])=C2[H])[C@]2([H])O[C@]3([H])C([H])([H])[C@@]4([H])[C@]5([H])C([H])([H])[C@]([H])(F)C6=C([H])C(=O)C([H])=C([H])[C@]6(C([H])([H])[H])[C@@]5(F)[C@@]([H])(O[H])C([H])([H])[C@]4(C([H])([H])[H])[C@@]3(O2)C(=O)C([H])([H])O[H])N=N1
[H]N(C(=O)N([H])C1=C([H])C([H])=C2N(C3=C(C2=C1[H])C1=C(C(=O)N([H])C1([H])[H])C1=C3C([H])([H])C([H])([H])C2=NN(C([H])=C12)C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N([H])C([H])([H])C(=O)N1C([H])([H])C([H])([H])N(C2=C([H])C([H])=C(N([H])C3=NC4=C(C([H])=N3)C([H])=C([H])C(OC([H])([H])[H])=C4C3([H])C([H])([H])C([H])([H])C([H])([H])C3([H])[H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N=C(N([H])[H])C1=C([H])C(=C([H])C([H])=C1[H])C1=NO[C@@](C(=O)N([H])C2=C([H])C([H])=C(C([H])=C2[H])C2=C([H])C([H])=C([H])C([H])=C2S(=O)(=O)N([H])C([H])([H])[H])(C([H])([H])N2N=NN=C2[H])C1([H])[H]
[H]OC1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C(S1)C1=C([H])C([H])=C(N([H])[H])C([H])=C1[H]
[H]N(C(=O)C([H])([H])N1C([H])=NC(=C1C([H])([H])N1C(=O)C(N([H])S(=O)(=O)C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])=C([H])C([H])=C1C([H])([H])[H])C([H])([H])[H])[C@@]1([H])C([H])([H])N([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(C1=NC2=C(C([H])=C([H])C([H])=C2Cl)C([H])=C1[H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])[C@@]3([H])N(C(=O)C([H])([H])[H])[C@@]([H])(C2([H])[H])C([H])([H])C([H])([H])C3([H])[H])C([H])([H])C1([H])[H]
[H]OC1=C(C([H])=C(C([H])=C1C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])[C@@]1([H])C(=O)OC([H])([H])C1([H])[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)C([H])([H])N(C1=C([H])C([H])=C([H])C([H])=C1C([H])([H])C([H])([H])[H])S(=O)(=O)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]OC(=O)C([H])([H])OC1=C([H])C([H])=C(C([H])=C1C([H])([H])[H])C([H])([H])N(C([H])([H])C(=O)N([H])C1=C([H])C([H])=C(Cl)C([H])=C1Cl)C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(C(=O)OC([H])([H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])S(=O)(=O)C1=C([H])C([H])=C([H])C([H])=C1C1=C([H])C(F)=C(C([H])=C1[H])C([H])([H])N1C(=NC(=C1C(=O)C([H])([H])C([H])([H])N(C(=O)C1=C([H])N=C([H])C([H])=C1[H])C1=NC([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]N([C@]([H])(C([H])([H])[H])C([H])([H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H])S(=O)(=O)C1=C([H])C(=C(Cl)C([H])=C1C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)N([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])N2C(SC3=C2C([H])=C([H])C([H])=C3[H])=N1)C1=NOC(=C1[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])C([H])=C2C(=N1)C(=O)N1C(=C2C2=C([H])C([H])=C(C([H])=C2[H])C([H])([H])[H])C(=O)N(C([H])([H])C2=C([H])C(=C([H])C(=C2[H])C(F)(F)F)C(F)(F)F)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(C(=O)[C@]1([H])N(C([H])([H])C([H])([H])C([H])([H])C1([H])[H])S(=O)(=O)C(\[H])=C(/[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)C([H])([H])[H])[C@@]1([H])C(=O)N(C(=O)C1([H])[H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C([H])C([H])=C([H])C([H])=C2OC([H])([H])[H])C([H])([H])C1([H])[H]
[H]C1=C(F)C(=NC2=C1OC(=N2)N1C([H])([H])C([H])([H])[N@]2C([H])([H])C([H])([H])[C@]1([H])C([H])([H])C2([H])[H])C([H])([H])[H]
[H]O[C@@]1([H])[C@@]([H])(O[C@]([H])(C([H])([H])Cl)[C@@]1([H])O[H])N1C([H])=NC2=C1N=C([H])N=C2N([H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])[N+]([O-])=O
[H]N(C(=O)N1C([H])([H])C([H])([H])C([H])(OC2=C([H])C([H])=NC([H])=C2[H])C([H])([H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C(Cl)C([H])=C1Cl
[H]OC1=C2C([H])=C([H])C([H])=C([H])C2=NC(=C1[H])C(=O)N([H])[C@@]([H])(C(=O)N(C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])[C@]([H])(C#N)N1C([H])([H])C([H])([H])N(C(=O)[C@]23C([H])([H])[C@]4([H])C([H])([H])[C@]([H])(C2([H])[H])C([H])([H])[C@@](C2=C([H])C([H])=C(C([H])=C2[H])C([H])([H])[H])(C4([H])[H])C3([H])[H])C([H])([H])C1([H])[H]
[H]OC(=O)C([H])([H])[C@]1([H])N([H])C(=O)C([H])([H])N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@]2([H])N(C(=O)[C@@]([H])(N([H])C(=O)[C@]([H])(N([H])C(=O)C([H])([H])[H])C([H])([H])SSC([H])([H])[C@@]([H])(N([H])C1=O)C(=O)O[H])C([H])([H])C(=O)N([H])[H])C([H])([H])SC2(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N([H])[H]
[H]O[C@]([H])(C([H])([H])N([H])C([H])([H])[H])[C@@]([H])(N1C([H])=C([H])C2=C1C(Br)=C([H])C([H])=C2[H])C1=C([H])C(F)=C([H])C([H])=C1[H]
[H]O\C(=C(\C#N)C(=O)N([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C1([H])C([H])([H])C1([H])[H]
[H]C1=C(C#N)C([H])=C([H])C(=N1)N1C([H])([H])C([H])([H])N(C2=C3C([H])=C([H])C([H])=C([H])C3=C(N=N2)C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])[C@@]1([H])C([H])([H])[H]
[H]N([H])C(=O)C1=NN=C(C([H])=C1[H])N1C([H])([H])C([H])([H])N(C(=O)C2=C([H])C([H])=C([H])C([H])=C2C(F)(F)F)C([H])([H])C1([H])[H]
[H]C1=C([H])C(Cl)=C([H])C(=N1)C1=C(C2=C([H])C([H])=C(C([H])=C2[H])S(=O)(=O)C([H])([H])[H])C([H])([H])C([H])([H])C1=O
[H]N1C([H])([H])C([H])([H])N(C2=C([H])C3=C([H])C([H])=C([H])C([H])=C3C([H])([H])N3C([H])=C([H])N=C23)C([H])([H])C1([H])[H]
[H]C1=NC(=C(O1)C1=NN=C(SC([H])([H])C([H])([H])C([H])([H])N2C([H])([H])C([H])([H])C3=C([H])C4=C(N=C(O4)C([H])([H])[H])C([H])=C3C([H])([H])C2([H])[H])N1C([H])([H])[H])C([H])([H])[H]
[H]N1C([H])=C(C([H])=O)C2=C1C([H])=C([H])C1=C2C([H])([H])[C@]([H])(N2C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]N1N=NN=C1[C@]1([H])N(C2=C([H])C([H])=C(C([H])=C2[H])C([H])([H])C([H])([H])C2=NC(=C([H])N2[H])C([H])([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]OC1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C(=O)N([H])[H]
[H]OC(=O)[C@]([H])(N([H])C(=O)C([H])([H])C([H])([H])[C@@]([H])(N([H])C(=O)C1=C([H])C([H])=C(C([H])=C1[H])N(C([H])([H])C#C[H])C([H])([H])C1=C([H])C2=C(N=C(N=C2O[H])C([H])([H])[H])C([H])=C1[H])C(=O)O[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C1=C([H])C(OC([H])([H])[H])=C(Cl)C([H])=C1Cl)C1=C(C#N)C([H])=NC2=C([H])C(OC([H])([H])C([H])([H])C([H])([H])N3N=NC([H])=C3[H])=C(OC([H])([H])[H])C([H])=C12
[H]OC(=O)C(=C(\[H])C1=C([H])N(C(=C1[H])C([H])([H])C1=C([H])N=C([H])C([H])=C1[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])\C([H])([H])[H]
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CCCCN1C2=NC3=C(N2C=C1C1=CC=CC=C1C)C(=O)NC(=O)N3C
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[Cl-].NCCCC(NC(=O)[C@@H]1CCCN1C(=O)[C@@H]1CCCC[C@H]1C1=CC=CC=C1)B(O)O
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[H]N(C(=O)C1=C([H])C2=C(S1)C([H])=C([H])C([H])=C2[H])[C@@]([H])(C(=O)N1C([H])([H])C([H])([H])C([H])(C2=C([H])C([H])=C(Cl)C([H])=C2[H])C([H])([H])C1([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)N([H])C([H])([H])[H])C1=C([H])C2=C(O\C(=C(\[H])C3=C([H])N(C4=NC([H])=C([H])C(N5C([H])([H])[C@@]6([H])O[C@]([H])(C([H])([H])C6([H])[H])C5([H])[H])=C34)C([H])([H])[H])C2=O)C([H])=C1[H]
[H]OC([H])([H])C([H])([H])C([H])([H])N1C([H])=NC2=C(N=C(N=C12)C#N)N([H])C([H])([H])C1=C([H])C(=C([H])C([H])=C1[H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]N(C([H])([H])[H])[C@@]1([H])C([H])([H])N(C(=O)C2=C([H])C3=C(N2[H])C(=C([H])C(Cl)=C3[H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N=C(N([H])[H])N([H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[C@]([H])(N([H])C(=O)[C@@]([H])(N(C(=O)C(\[H])=C(/[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C(=O)C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(F)C([H])=C1[H])C(=O)N([H])[C@@]([H])(C(=O)N([H])[C@@]([H])(C(=O)N([H])[C@@]([H])(C(=O)N([H])[H])C([H])([H])C([H])([H])C([H])([H])N=C(N([H])[H])N([H])[H])C([H])([H])C([H])([H])C([H])([H])N=C(N([H])[H])N([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)C([H])([H])N1N=C(C(=C1[H])C1=C([H])C([H])=C2N=C([H])C([H])=NC2=C1[H])C1=C([H])C([H])=C([H])C(=N1)C([H])([H])[H])C1=C([H])C(C#N)=C([H])C([H])=C1[H]
[H]OC1=C([H])C2=C(N=C(N=C2N(C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])[H])N([H])C2=C(C([H])=C([H])C([H])=C2[H])C([H])([H])[H])C([H])=C1[H]
[H]N(C(=O)[C@]([H])(N1C([H])([H])C([H])([H])C([H])([H])C2=C(C(=NN2C([H])([H])C([H])([H])[H])C([H])([H])[H])[C@]1([H])C([H])([H])C([H])([H])C1=C([H])C(F)=C(C(F)=C1[H])C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H]
[H]OC(=O)[C@@]([H])(N([H])C(=O)[C@]1(C([H])([H])OC([H])([H])C1([H])[H])S(=O)(=O)C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C(OC([H])([H])[H])C([H])=C([H])C([H])=C1OC([H])([H])[H]
[H]OC(=O)C([H])([H])C([H])([H])C([H])([H])C(\[H])=C(\[H])C([H])([H])[C@@]1([H])[C@@]([H])(O[H])C([H])([H])[C@@]([H])(O[H])[C@]1([H])C(\[H])=C(/[H])[C@@]([H])(O[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]OC([H])([H])[C@@]1([H])O[C@@]([H])(N2C([H])=NC3=C2N([H])C(=NC([H])([H])[C@@]3([H])O[H])C([H])([H])[H])C([H])([H])[C@@]1([H])O[H]
Cc1cnc(Nc2ccc(OCc3ccccc3)cc2)nc1-c1c[nH]c(c1)C(=O)N[C@H](CO)c1ccccc1
[H]N1N=C(N(C1=S)C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)N1C([H])([H])C([H])([H])C([H])(N2C(=O)N([H])C3=C2C([H])=C([H])C([H])=N3)C([H])([H])C1([H])[H])[C@@]1([H])C(=O)N(C([H])([H])C2([H])C([H])([H])C2([H])[H])C([H])([H])[C@]([H])(C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]C1=C([H])C2=C(C([H])=C1[H])C(=C([H])C([H])=C2[H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])OC([H])(C2=C([H])C([H])=C(F)C([H])=C2[H])C2=C([H])C([H])=C(F)C([H])=C2[H])C([H])([H])C1([H])[H]
[H]C1=NN(C([H])=C1C1=C([H])C2=C(C([H])=C1[H])C([H])([H])[C@]1([H])N(C(=O)C3=C([H])C4=C(C([H])=C3[H])C([H])([H])C([H])=N4)C([H])([H])C([H])([H])C([H])([H])[C@]21[H])C([H])([H])[H]
[H]N1C2=C(N=C1C([H])([H])C([H])([H])C([H])([H])N1N=C(Cl)C([H])([H])C([H])([H])C1=O)C(=O)[C@@]([H])(C(=O)N2C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]N(C([H])([H])C([H])([H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])[C@]2([H])OC3=C([H])C([H])=C([H])C([H])=C3OC2([H])[H])C([H])([H])C1([H])[H])S(=O)(=O)C([H])([H])[H]
[H]C#CC([H])([H])N([H])C1=NC([H])=NC2=C1C1=C(S2)C(=O)N(C([H])=N1)C1=C([H])C([H])=C2OC([H])([H])C([H])([H])OC2=C1[H]
[H]N1C(=O)N([H])[C@](C1=O)(C1=C([H])C([H])=C(C([H])=C1[H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C([H])([H])N1C(=O)C2=C(C([H])=C([H])C(OC([H])([H])[H])=C2[H])C1([H])[H]
[H]N([H])C1=C2C([H])=C(SC2=C(C([H])=N1)C(=O)N([H])C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)C([H])([H])C1=C(ON=C1C1=C(C([H])=C([H])C([H])=C1C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=NC(OC([H])([H])C([H])([H])OC([H])([H])C(F)(F)F)=C([H])C([H])=C1[H]
[H]ON([H])C(=O)C([H])([H])C([H])([H])C(=O)N1C([H])([H])C([H])([H])C([H])(OC2=C([H])C([H])=C(C([H])=C2[H])N2C([H])=NC([H])=C2[H])C([H])([H])C1([H])[H]
[H]O[C@@]1(N2C(=NC([H])([H])C2([H])[H])C2=C([H])C([H])=C([H])C([H])=C12)C1=C([H])C([H])=C([H])C([H])=C1Cl
CC1=CN2C(=CN=C2C(NC2=CC(CN3CCOCC3(C)C)=NS2)=N1)C1=CNN=C1
[H]N(C(=O)C([H])([H])OC1=C([H])C2=C(C([H])=C1[H])C(=C([H])C(=O)O2)C([H])([H])[H])C1=C(OC([H])([H])[H])C([H])=C([H])C(=C1[H])S(=O)(=O)N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H]
CC[Hg]SC1=CC=CC=C1C(O)=O
[H]C1=C(C(=O)N2C([H])([H])C([H])([H])N3C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@@]3([H])C2([H])[H])C2=C([H])C([H])=C([H])C(OC([H])([H])[H])=C2N1C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]C1=C([H])N2C(=C1[H])C(=NC1=C2C([H])=C([H])C(=C1[H])C(F)(F)F)N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N1C([H])=C([H])C2=C([H])C(=C([H])C([H])=C12)N([C@@]([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H])C1([H])C([H])([H])C([H])([H])N([H])C([H])([H])C1([H])[H]
[H]O[C@]([H])(C([H])([H])C(=O)C([H])([H])[C@@]1([H])C([H])([H])C([H])([H])[C@]([H])(C([H])([H])C([H])([H])N2C([H])([H])C([H])([H])N(C3=NC([H])=C([H])C4=C3C([H])([H])C([H])([H])O4)C([H])([H])C2([H])[H])C([H])([H])C1([H])[H])C(F)(F)F
[H]N1C([H])=C([H])C2=NC(=C([H])C2=C1[H])C([H])([H])N1C(=O)C([H])([H])N(C([H])([H])C1([H])[H])S(=O)(=O)C1=C([H])C2=C(S1)C([H])=C([H])C([H])=N2
[H]OC1=NC2=C([H])C(C#CC([H])([H])N3C([H])([H])C([H])([H])C([H])(C([H])([H])C4=C([H])C([H])=C([H])C(F)=C4[H])C([H])([H])C3([H])[H])=C([H])C([H])=C2N1[H]
[H]OC1=C([H])C(O[H])=C2C(=O)C([H])=C(OC2=C1[H])C1=C([H])C(O[H])=C(O[H])C([H])=C1[H]
[H]N(C(=O)C1=C(N([H])C2=NN([H])C([H])=C2[C@@]1([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]N([H])C([H])([H])C([H])([H])[C@@]([H])(N([H])C(=O)C1=C([H])C(Br)=C(S1)C1=C2C([H])=C([H])N([H])C2=NC([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C1=NC([H])=C([H])C(=C1[H])C([H])([H])[C@]1([H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2C([H])([H])C1([H])[H]
[H]C([H])([H])C1=C(C(=O)ON1C(=O)N1C([H])([H])C([H])([H])C(=O)C([H])([H])C1([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]ON([H])C(=O)[C@]1([H])N(C([H])([H])[C@@]([H])(N([H])C(=O)C([H])([H])OC([H])([H])[H])C1([H])[H])S(=O)(=O)C1=C([H])C([H])=C(OC([H])([H])C([H])([H])C([H])([H])[H])C([H])=C1[H]
[H]N1C(=O)N([H])[C@](C1=O)(C1=NC([H])=C([H])N=C1[H])C([H])([H])N1C(=O)C2=C(C([H])=C([H])C(OC([H])([H])[H])=C2[H])C1([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C(=O)N1C([H])([H])C([H])([H])[C@]2([H])C([H])([H])N(C([H])([H])C([H])([H])[C@](C3=C([H])C([H])=C([H])C([H])=C3[H])(C([H])([H])[H])C([H])([H])N(C([H])([H])[H])S(=O)(=O)C3=C([H])C([H])=C([H])C([H])=C3[H])C([H])([H])C([H])([H])[C@]12[H]
[H]N(C(=O)C1=C([H])C([H])=C([H])C([H])=C1C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C2(C3=C([H])C([H])=C([H])C([H])=C3C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]N([H])C(=S)N([H])\N=C(/C1=C([H])C([H])=C(F)C([H])=C1[H])C1=C(F)C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)C1=NN(C(=C1C([H])([H])N1N=C([H])N=C1[H])C1=C([H])C([H])=C(Cl)C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1Cl)C([H])([H])C1=C(C([H])=C(Cl)C([H])=C1Cl)C([H])([H])[H]
[H]N([H])C1=NC(=C([H])C([H])=N1)C1=C([H])C2=C(N1[H])[C@]([H])(C([H])([H])C([H])([H])C([H])([H])OC([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])N([H])C2=O
[H]OC(=O)[C@@]([H])(N([H])S(=O)(=O)C1=C([H])C([H])=C([H])C(=C1[H])C(F)(F)F)C([H])([H])C1=C([H])C(N([H])C(=O)C([H])([H])OC([H])([H])C([H])([H])OC([H])([H])C([H])([H])OC([H])([H])C([H])([H])OC([H])([H])[H])=C(OC([H])([H])C([H])([H])C([H])([H])N([H])C2=C([H])C([H])=C3C(=N2)N([H])C([H])([H])C([H])([H])C3([H])[H])C([H])=C1[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1C([H])([H])C([H])([H])C([H])(C([H])([H])C([H])([H])C(=O)C2=C([H])C3=C(C([H])=C2[H])N(C(=N3)C([H])([H])[H])C([H])([H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]ON([H])C(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=O)C([H])=C1C2=C(C([H])=C([H])C([H])=C2[H])C2=C1C([H])=C([H])C([H])=C2[H]
[H]N(C(=O)C([H])([H])[C@]1([H])C([H])([H])C([H])([H])C([H])([H])N2C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@]12[H])C1=C([H])C([H])=C(C([H])=C1C([H])([H])[H])C(=O)C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C(=O)C1=NN(C(=N1)C1=C(Cl)C([H])=C(Cl)C([H])=C1[H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]N(C1=N\C(=C(\[H])C2=C([H])C3=C(OC([H])([H])O3)C([H])=C2[H])C(=O)N1C([H])([H])[H])C([H])([H])C([H])([H])OC([H])([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])N1C([H])([H])C([H])([H])C([H])(C([H])([H])[C@@]2([H])C(=O)C3=C(C([H])=C([H])C([H])=C3[H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]O[C@]([H])(C(=O)N1C([H])([H])SC(C([H])([H])[H])(C([H])([H])[H])[C@@]1([H])C(=O)N([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)C([H])([H])OC1=C2C([H])=C([H])N=C([H])C2=C([H])C([H])=C1[H])C([H])([H])SC([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)C1=C([H])C([H])=C([H])C(=C1[H])C(F)(F)F)C([H])([H])C(=O)N([H])[C@@]1([H])C([H])([H])C([H])([H])[C@@]([H])(N(C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[H])[C@@]([H])(C([H])([H])S(=O)(=O)C2=C([H])C([H])=C([H])C([H])=C2[H])C1([H])[H]
[H]OC(=O)C1=C([H])C(OC2=C([H])C([H])=C(C([H])=C2[H])C([H])([H])C([H])([H])N([H])C([H])([H])[C@]([H])(O[H])C2=C([H])C(Cl)=C([H])C([H])=C2[H])=C([H])C([H])=C1[H]
[H]OC1=C(Br)C([H])=C(C([H])=C1[H])[C@]([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C(C(=O)N([H])C1=NN=C([H])S1)(C([H])([H])[H])C([H])([H])[H]
[H]N(C([H])([H])C1=C([H])N2C(=NC3=C([H])C([H])=C(C([H])=C3C2=O)C([H])(C([H])([H])[H])C([H])([H])[H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])N=C1[H]
NC(=O)[C@@H]1CCCN1C(=O)CCNC(=O)C1=CC=C(C=C1)C1=CC=CC=C1
[H]N(C(=O)C([H])([H])C([H])([H])OC([H])([H])[H])S(=O)(=O)C1=C([H])C([H])=C([H])C([H])=C1C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1C(=O)N(N=C1C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1C(F)(F)F
[H]N([H])C(=O)N([H])[C@@]1(C([H])([H])[H])C([H])([H])C([H])([H])[C@]2(C([H])([H])[H])C([H])([H])C([H])([H])[C@@]3(C(=C([H])C(=O)[C@]4([H])[C@@]5(C([H])([H])[H])C([H])([H])C([H])([H])C(=O)C(C([H])([H])[H])(C([H])([H])[H])[C@]5([H])C([H])([H])C([H])([H])[C@@]34C([H])([H])[H])[C@]2([H])C1([H])[H])C([H])([H])[H]
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[H]N1C2=C(C(=C([H])C1(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C1=C(C([H])=C2[H])C2=C([H])C(Cl)=C([H])C([H])=C2O[C@]1([H])OC([H])([H])[H]
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[H]C1=C([H])C2=C(S1)C(=NC(=N2)C(F)(F)F)C(=O)C1=NC([H])=C([H])C([H])=C1[H]
[H]C([H])=C([H])C([H])([H])SC1=C([H])C([H])=C2C3=C(C(=O)OC([H])([H])C([H])([H])[H])C(=O)N=C3C3=C2C1=C([H])C([H])=C3[H]
[H]N(C1=NC2=C(C([H])=N1)C([H])=C(C(=O)N2C1([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C([H])([H])[H])C1=NC([H])=C(C([H])=C1[H])N1C([H])([H])C([H])([H])N([H])C([H])([H])C1([H])[H]
[H]N(C1=NC2=C(N=NN2C2=C1C([H])=C([H])C([H])=C2[H])S(=O)(=O)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H])[C@@]([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H]
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[H]N(C(=O)C1=C([H])C(OC([H])([H])C([H])=C(C([H])([H])[H])C([H])([H])[H])=C([H])C(OC2=C([H])C([H])=C(C([H])=C2[H])S(=O)(=O)C2([H])C([H])([H])C2([H])[H])=C1[H])C1=NC(=C([H])S1)C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]N([H])C(=O)C([H])([H])C([H])([H])N1C(=NC2=C([H])C(=C([H])C([H])=C12)C(=O)N(C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H])N([H])C(=O)C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C1=C([H])C([H])=C2C(=C1[H])C([H])([H])N(C([H])([H])C([H])([H])N1C(=O)N(C([H])([H])C3=C([H])C(=C([H])C([H])=C3[H])C(F)(F)F)C([H])([H])C1([H])[H])C2([H])[H]
[H]N(C(=O)C([H])([H])[H])C([H])([H])C([H])([H])C1=C2N(C3=C([H])C([H])=C(Cl)C([H])=C13)C([H])([H])C([H])([H])C([H])([H])C1=C2C([H])=C([H])C([H])=C1[H]
[H]OP(=O)(O[H])OC([H])([H])C1(C([H])([H])OP(=O)(O[H])O[H])C([H])([H])[C@]1([H])N1C([H])=NC2=C(N=C(Cl)N=C12)N([H])C([H])([H])[H]
[H]OC([H])([H])[C@@]([H])(N([H])S(=O)(=O)C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C([H])([H])C1=C([H])C([H])=C(N([H])C(=N[H])N([H])[H])C([H])=C1[H])P(=O)(OC1=C([H])C([H])=C([H])C([H])=C1[H])OC1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H]
[H]C1=C(C#N)C([H])=C(F)C(=C1[H])N1C([H])([H])C([H])([H])N(C(=O)C2=C([H])C(=C([H])C([H])=C2OC([H])([H])C(F)(F)F)S(=O)(=O)C([H])([H])[H])C([H])([H])C1([H])[H]
[H]C1=C([H])C(=C([H])C([H])=C1[N+]([O-])=O)C([H])([H])C(=O)N(C([H])([H])[H])[C@]1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@]1([H])N1C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(C(=O)[C@]1([H])C([H])([H])N([H])C([H])([H])C([H])([H])[C@]1([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C2=C(C([H])=C1Cl)C(=O)N([H])C([H])=C2[H]
[H]N([H])C1=NC2=C(N=C(C([H])=C2[H])C([H])([H])N([H])C2=C([H])C([H])=C([H])C3=C2C([H])=C([H])C([H])=C3[H])C(=N1)N([H])[H]
[H]N([H])C1=NC([H])([H])C([H])([H])C([H])([H])S1
[H]OC1=C([H])C2=C(C(=O)C(O[H])=C(O2)C2=C([H])C([H])=C(F)C([H])=C2[H])C(O[H])=C1[H]
[H]C1=C(F)C([H])=C(Cl)C(=C1[H])[C@@]([H])(N1C([H])([H])C([H])([H])C([H])(N2C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H])C([H])([H])N(C(=O)C([H])([H])C1=C([H])C(=C([H])C(=C1[H])C(F)(F)F)C(F)(F)F)C([H])([H])[H]
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CNC(=O)\C=C1\COC2=CC(OS(=O)(=O)C3=CC=C(C=C3)S(C)(=O)=O)=CC=C12
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[H]N1C([H])([H])C([H])([H])[C@]([H])(N(C(=O)C2=C(C([H])=C([H])C([H])=C2[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C2([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C1([H])[H]
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[H]O[C@]([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C(=C1[H])N(C([H])([H])C1=C([H])C([H])=C([H])N=C1[H])S(=O)(=O)C([H])([H])C([H])([H])[H]
[H]O[C@]([H])(C1=C([H])C([H])=C([H])N=C1[H])C([H])([H])N([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C(N([H])C(=O)C([H])([H])C2=C([H])SC(=N2)N([H])C([H])([H])[H])C([H])=C1[H]
[H]N1C(=O)C2=C3C([H])=C(OC4=C(C#N)C([H])=C([H])C(=C4[H])C([H])([H])N4C([H])=NC([H])=C4C([H])([H])N([H])C([H])([H])C([H])([H])C1([H])[H])C([H])=C([H])C3=C([H])C([H])=C2[H]
[H]N(C1=NC([H])=NC2=C1C(OC([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H])=NN2[H])C1=C([H])C([H])=C(OC([H])([H])C2=NC([H])=C([H])C([H])=C2[H])C(Cl)=C1[H]
[H]O[C@@]1([H])[C@@]([H])(O[C@]([H])(C([H])([H])C([H])([H])[H])[C@@]([H])(O[H])[C@]1([H])O[H])C1=C([H])C([H])=C(Cl)C(=C1[H])C([H])([H])C1=C([H])N=C(N=C1[H])C1=C([H])SC([H])=C1[H]
[H]N(C1=NC(=C(N=C1C([H])([H])C([H])([H])[H])N([H])C([H])(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H])C1=C(Cl)C([H])=C(Cl)C([H])=C1Cl
[H]N([H])[C@]([H])(C(=O)N1C([H])([H])C2=C(C([H])=C(C([H])=C2[H])C([H])([H])[H])C1([H])[H])[C@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])[H]
COC1=CC=C(C=C1)C1=[N+]2C(C=C1)=CC1=C(C)C(CCC(=O)NCCCCCC(=O)NCCCN3N=C(C(=O)NC4C[C@@H]5CCC[C@@H](C4)N5C)C4=CC=CC=C34)=C(C)N1[B-]2(F)F
[H]OC1=NSC(N([H])C2=C(C([H])=C([H])C([H])=C2[H])C(F)(F)F)=C1C#N
[H]N1C([H])=C(C(=O)[C@@]2([H])N([H])[C@]([H])(SC2([H])[H])C2=C([H])C([H])=C([H])N=C2[H])C2=C1C([H])=C([H])C(OC([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])=C2[H]
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[H]O[C@@]1([H])C([H])([H])C(=O)O[C@]([H])(C(\[H])=C(/[H])C2=C(C3=C([H])C([H])=C(F)C([H])=C3[H])C3=C([H])C([H])=C([H])C([H])=C3N=C2C([H])(C([H])([H])[H])C([H])([H])[H])C1([H])[H]
[H]OC([H])([H])C1=C([H])C([H])=C(C(N([H])C(=O)N([H])C2=C([H])C(C#N)=C([H])C([H])=C2[H])=C1[H])C([H])([H])N1C([H])([H])C([H])([H])C([H])(C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
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[H]N([H])S(=O)(=O)N([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@]([H])(N([H])S(=O)(=O)C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C(=O)N([H])C1=NC(=C([H])S1)C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C1=NC2=C(C([H])=C1[H])C([H])=C([H])C([H])=C2S(=O)(=O)N1C([H])([H])C([H])([H])C([H])(C(=O)N2C3=NC4=C([H])C([H])=C([H])C([H])=C4N3C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
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[H]OC(=O)C([H])([H])[C@]([H])(C1=C([H])C([H])=C(OC2=C(Cl)C([H])=C(Cl)C([H])=C2[H])C([H])=C1[H])C([H])([H])[H]
[H]OC1=C([H])C([H])=C(N([H])C(=O)N([H])C2=C([H])C([H])=C(N([H])C(=O)C3=C(O[H])C([H])=C([H])C([H])=C3[H])C([H])=C2[H])C([H])=C1O[H]
[H]OC1=C([H])C([H])=C(C([H])=C1[H])[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)C([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=N[H])N([H])[H])C(=O)N([H])[H]
[H]N(C(=S)N([H])C([H])([H])C([H])([H])C1=C([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C(=O)C1=C([H])C([H])=C(Br)O1
[H]OC1=C(Cl)C([H])=C2C(=C1[H])[C@@]([H])(C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N(C1([H])C([H])([H])C([H])([H])C1([H])[H])S(=O)(=O)C([H])([H])[H])C([H])([H])N(C([H])([H])[H])C([H])([H])C2([H])[H]
[H]N(C(=O)C([H])([H])N1C(=O)N(C2=C1C([H])=C(C([H])=C2C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C2C(=C1[H])C([H])([H])[C@]1(N(C(=O)N([H])C1=O)C([H])([H])[H])C2([H])[H]
[H]N(C1=NC([H])=NC2=C([H])C(OC([H])([H])C([H])([H])C([H])([H])N3C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C3([H])[H])=C([H])C(OC3([H])C([H])([H])C([H])([H])OC([H])([H])C3([H])[H])=C12)C1=C(Cl)C([H])=C([H])C2=C1OC([H])([H])O2
[H]C1=C([H])C(=C([H])C(=C1[H])C1=NOC(=C1C(=O)N(C1=C([H])C([H])=C(Cl)C([H])=C1[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])[H]
[H]O[C@@]([H])(C(=O)N([H])[C@@]1([H])C2=C(C([H])=C(C([H])=C2[H])C([H])([H])N2C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C([H])([H])C1([H])[H])[C@]([H])(O[H])C([H])([H])S(=O)(=O)C1=C([H])C([H])=C([H])C(=C1[H])C(F)(F)F
[H]N([H])S(=O)(=O)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])OS(=O)(=O)C(F)(F)F
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[H]O[C@]([H])(C1=C([H])C([H])=C2C([H])=C([H])C(=C([H])C2=C1[H])C([H])([H])[S@@](=O)C1=C([H])C([H])=C([H])C(=C1[H])C([O-])=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
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[H]N([H])C1=C([H])C(=NC2=NC(=NN12)C1=C([H])C([H])=C([H])O1)N1C([H])([H])C([H])([H])N2C([H])([H])[C@]([H])(C([H])([H])N([H])[H])C([H])([H])C([H])([H])[C@@]2([H])C1([H])[H]
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[H]N(\C(=C1/C(=O)N(N=C1C([H])([H])[H])C1=NC2=C([H])C([H])=C([H])C([H])=C2S1)C([H])([H])[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
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[H]N(C(=O)C1=C([H])C(=C(Br)C([H])=C1[H])S(=O)(=O)N(C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)C([H])([H])[H])C([H])([H])C([H])([H])C1=C([H])N([H])C2=C1C([H])=C(C([H])=C2[H])C([H])([H])C([H])([H])N([H])C(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]N(C([H])([H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])N([H])S(=O)(=O)C2=C3C([H])=C([H])C([H])=C([H])C3=C([H])C([H])=C2[H])C([H])([H])C1([H])[H])[C@]1([H])C([H])([H])C2=C([H])C(OC([H])([H])[H])=C([H])C([H])=C2C([H])([H])C([H])([H])C1([H])[H]
[H]N(\C([H])=C(/[H])C1=C(C#N)C(SC([H])([H])[H])=NS1)C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]N(C(=O)C1(C(=O)N([H])C2=C([H])C([H])=C(OC3=C([H])C([H])=NC4=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C([H])=C34)C(F)=C2[H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]N(C(=O)N1C([H])([H])C([H])([H])C([H])(N2C(=O)N([H])C3=C2C([H])=C([H])C([H])=N3)C([H])([H])C1([H])[H])[C@@]1([H])C2=NC(=C([H])N2C([H])([H])[C@]([H])(C2=C([H])C([H])=C([H])C(F)=C2F)C([H])([H])C1([H])[H])C([H])([H])[H]
[H]ON1C2=C([H])C([H])=C(\C(=N/C([H])([H])C([H])([H])C3=C([H])C([H])=C([H])C([H])=C3[H])C2=NC11C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])[N+]([O-])=O
[H]N(C(=O)C([H])([H])[C@@]1([H])N(C([H])=C([H])N([H])C1=O)S(=O)(=O)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H])[C@@]1([H])C2=C(N([H])C(=O)C1([H])[H])C([H])=C([H])C([H])=C2[H]
[H]N(C(=O)C1=C(N(N(C1=O)C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C(OC2=C3C([H])=C([H])C(OC([H])([H])[H])=C([H])C3=NC([H])=C2[H])C(F)=C1[H]
[H]C([H])([H])OC1=C(OC([H])([H])[H])C(Br)=C(C(Br)=C1Br)C([H])([H])[C@@]1([H])C(=O)C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]C1=NN(C2=C1C(=O)N(C(OC([H])([H])[H])=N2)C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC1=C([H])C([H])=C2C(=C1[H])[C@@]1(C([H])([H])[H])C([H])([H])C([H])([H])N(C([H])([H])C3=C([H])C(=C(I)C([H])=C3[H])[N+]([O-])=O)[C@@]([H])(C2([H])[H])[C@@]1([H])C([H])([H])[H]
[H]OC(=O)C([H])([H])C([H])([H])C1=C([H])N([H])C(\C([H])=C2/C(=O)N([H])C3=C([H])C(=C([H])C([H])=C23)C2=C([H])C([H])=C(OC([H])([H])[H])C([H])=C2[H])=C1C([H])([H])[H]
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[H]C1=C(C2=C([H])C([H])=C([H])C([H])=C2N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H])S(=O)(=O)C1=C([H])C([H])=C([H])C2=C([H])C([H])=C([H])C([H])=C12
[H]N([H])C1=NC(=C([H])C(=C1[H])C([H])([H])[H])C([H])([H])[C@@]1([H])C([H])([H])N([H])C([H])([H])[C@@]1([H])OC([H])([H])C([H])([H])N([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1OC([H])([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C1=C2C(=C([H])C3=C([H])C(OC([H])([H])C4=C([H])C([H])=C([H])C([H])=C4[H])=C([H])C([H])=C13)C(=O)OC2([H])[H]
[H]N(C(=O)C1=C(Cl)C([H])=C([H])C(=C1[H])N1C([H])=NN=C1[H])C([H])([H])C([H])([H])SC([H])([H])C([H])([H])[H]
[H]N([H])C(=O)C1=C([H])C([H])=C([H])C2=C1N=C(N2[H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])S(=O)(=O)N(C([H])([H])[H])C([H])([H])[H]
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[H]N([H])S(=O)(=O)C1=NN=C(S1)N([H])C(=O)C([H])([H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
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[H]N([H])C([H])([H])C(=O)N([H])C([H])([H])C(=O)N([H])C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)N([H])[H]
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[H]C1=C([H])N(C([H])=N1)[C@@]([H])(C1=C([H])C([H])=C(F)C([H])=C1[H])C1=C2N(C([H])=C([H])C2=C([H])C(Br)=C1[H])C([H])([H])C([H])([H])[H]
[H]N([C@]([H])(C1=NC([H])=C(N1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])[C@@]1([H])C([H])([H])C(=O)N([H])S1(=O)=O)S(=O)(=O)C1=C([H])C(=C([H])C([H])=C1[H])C(F)(F)F
[H]N(C1=NN([H])C(=C1[H])C([H])([H])[H])C1=NC(SC2=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C([H])=C2[H])=NC2=C([H])C([H])=C([H])C([H])=C12
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[H]OC1=C([H])C(=C(Cl)C([H])=C1[H])C1=C([H])C2=C(C3=C([H])C(O[H])=C([H])C([H])=C3N2[H])C2=C1C(=O)N([H])C2=O
[H]OC1=C([H])C([H])=C([H])C(N([H])C2=NC([H])=C([H])C(=N2)C2=C(N=C(S2)N([H])C([H])([H])[H])C([H])([H])[H])=C1[H]
[H]N=C(N([H])[H])C1=C([H])C(=C(SC([H])([H])[H])S1)C1=C([H])SC(=N1)N([H])C1=C([H])C2=C(OC([H])([H])O2)C([H])=C1[H]
[H]N(C1=NC2=C(C(=N1)C1=C([H])C([H])=C([H])C([H])=C1Cl)C([H])([H])N([H])C(=O)N2C1=C(Cl)C([H])=C([H])C([H])=C1Cl)C([H])([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]1([H])N(C(=O)[C@@]([H])(N([H])C(=O)[C@@]2([H])N([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C2=C([H])N([H])C([H])=N2)C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])N([H])C([H])=N1)C([H])([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])[C@@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
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[H]OC(=O)C1=C([H])C([H])=C([H])C([H])=C1C(=O)C1=C([H])C([H])=C([H])C(OC([H])([H])C([H])([H])C([H])([H])OC2=C(C([H])=C(C(O[H])=C2[H])C2=C([H])C([H])=C(F)C([H])=C2[H])C([H])([H])C([H])([H])[H])=C1C([H])([H])C([H])([H])C([H])([H])[H]
[H]N(C1=C(C([H])=C([H])C([H])=C1C([H])(C([H])([H])[H])C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])S(=O)(=O)N([H])C([H])([H])C1(C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]C1=C(N=C2C([H])=C([H])C(Br)=C([H])N12)C1=C([H])C([H])=C(C([H])=C1[H])N(C([H])([H])[H])C([H])([H])[H]
[H]N([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC2=C(O1)C([H])=C([H])C(=C2[H])C([H])(C([H])([H])[H])C([H])([H])[H]
CC1=CN(C=N1)C1=CC=CC(NC(=O)C2=CC(NC3=NC=CC(=N3)C3=CN=CC=C3)=C(C)C=C2)=C1
[H]N(C1=NC(=C([H])C([H])=N1)C1=C([H])N=C(N1C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)C([H])([H])[H]
[H]OC1=C([H])C(O[H])=C(Cl)C(=C1Cl)C1=C([H])C2=C([H])N=C(N=C2N(C1=O)C([H])([H])[H])N([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)N([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC(OC([H])([H])[H])=NC(=N1)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C(=O)N(C([H])([H])[H])C([H])([H])C([H])([H])N([H])C([H])([H])[H]
[H]ON([H])C(=O)[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)OC([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H]
[H]N(C(=O)C1=C2N(C([H])=C1[H])[C@@]([H])(SC2([H])[H])C1=C([H])C([H])=C([H])N=C1[H])C1=C([H])C(=C([H])C([H])=C1[H])C(=O)C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C([H])=C([H])C([H])([H])N1C([H])([H])[C@@]([H])(N(C([H])([H])[C@@]1([H])C([H])([H])[H])[C@@]([H])(C1=C([H])C([H])=C(C([H])=C1[H])C(=O)N([H])C([H])([H])C([H])([H])[H])C1=C([H])C(OC([H])([H])[H])=C([H])C([H])=C1[H])C([H])([H])[H]
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[H]OC(=O)C([H])([H])[C@]([H])(N([H])C(=O)[C@@]1([H])N2N(C(=O)C([H])([H])C([H])([H])[C@]([H])(N([H])C(=O)C3=C([H])C([H])=C([H])C([H])=C3[H])C2=O)C([H])([H])C([H])([H])C1([H])[H])C([H])=O
[H]N([C@]([H])(C(=O)O[C@@]1([H])[C@@]2([H])C([H])([H])[C@]3([H])C([H])([H])[C@]([H])(C2([H])[H])C([H])([H])[C@@]1([H])C3([H])[H])C([H])([H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H])[C@]1([H])C([H])([H])C([H])([H])C([H])([H])N2C(=O)N(C(=O)[C@]([H])(C([H])([H])[H])[C@]12[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]O[C@@]1([H])C([H])([H])[C@@]([H])(O[C@]1([H])C([H])([H])OP([O-])(=O)OP([O-])(=O)OP([O-])(=O)OP([O-])(=O)OC([H])([H])[C@@]1([H])O[C@@]([H])(N2C([H])=C([H])C(=O)N([H])C2=O)[C@]([H])(O[H])[C@]1([H])O[H])N1C([H])=C([H])C(=NC1=O)N([H])[H]
[H]N(C1=NC([H])=NC2=C1SC1=C2C([H])=C([H])C([H])=N1)C1=C([H])C([H])=C([H])C(Br)=C1[H]
CC(C)(CO)[NH2+]Cc1ccc(o1)-c1ccccc1
[H]C1=C([H])C2=C(C([H])=C1[H])C(=NS2)N1C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])C([H])([H])N2C(=O)C([H])([H])C3(C([H])([H])C([H])([H])C([H])([H])C3([H])[H])C([H])([H])C2=O)C([H])([H])C([H])([H])C1([H])[H]
[H]N([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@]([H])(N([H])C(=O)OC([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C(=O)C1=NOC(=N1)C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C(=O)N1C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2F)C([H])([H])C1([H])[H]
[H]N1C(=NC2=C(C(F)=C([H])C([H])=C12)C([H])([H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N1C([H])([H])[C@@]([H])(N(C([H])([H])C2=C([H])C([H])=C(C#N)C([H])=C2[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])[C@@]1([H])C(=O)N1C([H])([H])SC([H])([H])C1([H])[H]
[H]C1=C2C(ON=C2C2([H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])OC3=C([H])C([H])=C(C([H])=C3OC([H])([H])[H])C(=O)C(F)(F)F)C([H])([H])C2([H])[H])=C([H])C(F)=C1[H]
[H]N(C([H])([H])C([H])([H])C1=C(N([H])C2=C1C([H])=C([H])C([H])=C2[H])C1=C([H])C(=C([H])C(=C1[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1=C([H])N=C([H])C([H])=C1[H]
[H]OC1=C([H])C2=C([H])C([H])=C(C([H])=C2C([H])=C1[H])C1=C(O[H])C([H])=C([H])C([H])=C1[H]
[H]OC1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)N(C1=C(Cl)C([H])=C([H])C([H])=C1C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]N(C(=O)C1(N([H])C(=O)C(F)(F)Cl)C([H])([H])C1([H])[H])[C@@]([H])(C1=C(F)C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C([H])C(F)=C1C(=O)OC([H])([H])[H])C([H])([H])[H]
[H]N(C1=NC2=C([H])C(=C([H])C([H])=C2N2C([H])=NC([H])=C12)N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H])C1=C(Cl)C([H])=C([H])C([H])=C1C([H])([H])[H]
[H]N([H])C1=C([H])C2=NC([H])=NC(N([H])C3=C([H])C([H])=C(Br)C([H])=C3[H])=C2C([H])=N1
[H]N([H])C1=NC2=C(C([H])=NN2C([H])=C1[H])C(=O)N([H])C1=C([H])N(N=C1C1=C(C([H])=C([H])C(=C1[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])[H]
[H]OC1([H])C([H])([H])C([H])([H])N(C([H])([H])[C@@]([H])(N([H])C2=C(C([H])=NC([H])=C2[H])S(=O)(=O)N([H])[C@]([H])(C(=O)N2C([H])([H])C([H])([H])C([H])(C([H])([H])C([H])([H])F)C([H])([H])C2([H])[H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N(C(=O)N([H])C([H])(C([H])([H])[H])C([H])([H])[H])C1=C([H])C(=NC(=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C(=O)N([H])[C@]([H])(C(=O)N1C([H])([H])C([H])([H])N(C(=O)OC([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C1([H])[H])C([H])([H])C([H])([H])C(=O)OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)[C@](N([H])C(=O)O[C@@]1([H])[C@@]2([H])C([H])([H])[C@]3([H])C([H])([H])[C@]([H])(C2([H])[H])C([H])([H])[C@@]1([H])C3([H])[H])(C([H])([H])[H])C([H])([H])C1=C([H])N([H])C2=C1C([H])=C(F)C([H])=C2[H])C([H])([H])[C@]([H])(N([H])C(=O)C([H])([H])C([H])([H])C(=O)OC([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H])[C@]([H])(C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)C1=C(C([H])=C(OC([H])([H])[H])C([H])=C1[H])S(=O)(=O)C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])C([H])([H])[H]
[H]N([H])C([H])([H])C1=C(N2N=C(N=C2N=C1C([H])([H])[H])N1C([H])([H])C([H])([H])SC([H])([H])C1([H])[H])C1=C(Cl)C([H])=C(Cl)C([H])=C1[H]
[H]C1=NC([H])=C(OC([H])([H])[C@@]2([H])N(C([H])([H])[H])C([H])([H])[C@]3([H])C([H])([H])N(C4=NN=C(C([H])=C4[H])C4=C([H])C([H])=C([H])C([H])=C4[H])C([H])([H])[C@]23[H])C([H])=C1[H]
[H]N(C1=NC(Cl)=C([H])N(C1=O)[C@]([H])(C([H])([H])OC([H])([H])[H])C1([H])C([H])([H])C1([H])[H])C1=C(N=C(OC([H])(F)F)C([H])=C1C([H])([H])[H])C([H])([H])[H]
[H]N1C([H])([H])C([H])([H])N(C2=NC(OC([H])([H])C3=C([H])C([H])=C([H])C([H])=C3[H])=NC3=C2N(C([H])=N3)C([H])([H])[H])C([H])([H])C1([H])[H]
CS(=O)(=O)C1=CC2=C(C=C1)C(=O)N([C@@H](CC1CCCCC1)C(=O)NC1=NC=CS1)C(=O)N2
[H]N([H])[C@]1([H])C([H])([H])[C@]([H])(C2=C(C([H])=NC([H])=C2[H])C([H])([H])C(=O)C2=C([H])C([H])=C(F)C(=N2)C2=C(F)C([H])=C([H])C([H])=C2F)C([H])([H])C(C([H])([H])[H])(C([H])([H])[H])C1([H])[H]
[H]N(C(=O)N1N=C(C2=C([H])C(=C([H])C([H])=C2[H])C([H])([H])[H])[C@@]([H])(C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C1([H])[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]OC1=NN2C(=N1)C(=C(N=C2C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C(C([H])=C([H])C([H])=C1[H])C1=NN([H])N=N1
[H]N(C(=O)C([H])([H])SC1=NN=C(N1C([H])([H])C1=C([H])C([H])=C([H])O1)C1=C(OC([H])=C1[H])C([H])([H])[H])C1=C(OC([H])([H])[H])C([H])=C([H])C(=C1[H])C([H])([H])[H]
[H]OC(=O)C1=C([H])N=C(\C([H])=C(/[H])C2=C([H])C([H])=C([H])C(=C2[H])[C@]([H])(SC([H])([H])C2(C([H])([H])C(=O)O[H])C([H])([H])C2([H])[H])C([H])([H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2C(O[H])(C([H])([H])[H])C([H])([H])[H])C([H])=C1[H]
[H]N([H])C1=NC([H])=C(C([H])=C1OC([H])([H])C1=C(Cl)C([H])=C([H])C([H])=C1Cl)C1=C([H])C([H])=C(C([H])=C1[H])C(=O)N1C([H])([H])C([H])([H])C([H])([H])[C@]1([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(C1=NN2C([H])=C([H])C([H])=C(N([H])C([H])([H])C3=C([H])C([H])=C([H])C([H])=C3N(C([H])([H])[H])S(=O)(=O)C([H])([H])[H])C2=N1)C1=C([H])C([H])=C(C([H])=C1[H])N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H]
[H]OC(=O)C([H])([H])[C@]([H])(N([H])C(=O)C([H])([H])N(C(=O)C([H])([H])C1=C([H])C([H])=C(N([H])C(=O)N([H])C2=C([H])C([H])=C([H])C([H])=C2C([H])([H])[H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])OC([H])([H])[H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]N(C(=O)[C@@]([H])(N([H])C(=O)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C([H])([H])N([H])C1=C([H])C([H])=C(OC(F)(F)F)C([H])=C1[H]
[H]OC(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@]([H])(C1=C([H])N=C([H])C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])N([H])S(=O)(=O)C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]ON([H])C(=O)C([H])([H])N(OC([H])([H])C1=C([H])C([H])=C(OC([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])=C1[H])S(=O)(=O)C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]C#CC(=O)N([H])C1=C([H])C2=C(N=C([H])N=C2C([H])=C1[H])N([H])C1=C([H])C([H])=C([H])C(Br)=C1[H]
[H]OC(=O)C([H])([H])C([H])([H])C([H])([H])N1C(=O)N([H])[C@]([H])(C2=C([H])C([H])=C([H])C([H])=C2OS(=O)(=O)C2=C([H])C([H])=C([H])C([H])=C2[N+]([O-])=O)C(C(=O)OC([H])([H])[H])=C1C([H])([H])[H]
[H]C1=C([H])C2=C(C([H])=C1[H])C(=O)N(C2=O)C([H])([H])C([H])([H])C#CC1=C([H])C2=C(C([H])=C1[H])N1C(=NN=C1C([H])([H])N=C2C1=C([H])C([H])=C([H])C([H])=C1F)C([H])([H])[H]
[H]C1=C([H])N2C(=C1[H])C(OC(=O)C([H])([H])[H])=C(C1=C([H])C([H])=C([H])C([H])=C1[H])[S@](=O)C1=C([H])C([H])=C([H])C([H])=C21
[H]N([H])C1=C(C([H])=NC([H])=C1[H])C1=C([H])C2=C([H])C([H])=C(OC([H])([H])[H])C([H])=C2C([H])=C1[H]
[H]N(C(=O)C([H])([H])C1=C([H])N=C(S1)N([H])C1=NC([H])=NC2=C([H])C(OC([H])([H])C([H])([H])OC([H])([H])[H])=C(OC([H])([H])[H])C([H])=C12)C1=C([H])C(F)=C([H])C([H])=C1[H]
[H]N(C(=O)C1=C([H])C2=C(C([H])=C1[H])C1=C(C([H])=C([H])C([H])=C1[H])C2([H])[H])C([H])([H])C#CC([H])([H])N1C([H])([H])C([H])([H])N(C2=C([H])C([H])=C([H])C(Cl)=C2Cl)C([H])([H])C1([H])[H]
[H]C1=C([H])C([H])=C2N(C(=NC2=C1[H])C(=O)C1([H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])[C@]2(C3=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C([H])=C3[H])C([H])([H])N(C(=O)C3=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C(OC([H])([H])[H])=C3[H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]N(C(=O)C1=C([H])C([H])=C(Br)O1)C1=C([H])C([H])=C(C([H])=C1[H])C1=NN=C(C([H])=C1[H])N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]OC(=O)C([H])([H])OC1=C(I)C([H])=C(C([H])=C1I)C([H])([H])C1=C(OC2=C([H])C([H])=C([H])C([H])=C12)C([H])([H])[H]
[H]C1=C([H])C([H])=C(C2=NOC(=C2C(=O)N(C2=C(C([H])=C(Cl)C([H])=C2[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C(Cl)=C1[H]
[H]N(C([H])([H])C1=C([H])C(=C([H])C([H])=C1[H])C1=C([H])C([H])=C(C#N)C([H])=C1[H])[C@]1([H])C([H])([H])N2C(=O)N(C(=O)[C@]2([H])C1([H])[H])C1=C([H])C(Cl)=C([H])C(Cl)=C1[H]
[H]N(C(=O)C1=C([H])C2=C(OC([H])([H])O2)C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C(=C1[H])C1=C([H])C(=C([H])C([H])=C1[H])C([H])([H])N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(C(=O)C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)C([H])([H])[H])C1=C([H])C(=NC(=N1)C1=C([H])C([H])=C([H])C([H])=N1)N1N=C(C([H])=C1C([H])([H])[H])C([H])([H])[H]
[H]N=C(N([H])[H])N([H])C([H])([H])C([H])([H])C([H])([H])[C@@]([H])(N([H])C(=O)C([H])([H])N1C(=O)C([H])([H])N(C([H])([H])C1([H])[H])S(=O)(=O)C1=C([H])C(Cl)=C(Cl)C([H])=C1[H])C(=O)C1=NC([H])=C([H])S1
[H]C1=C2N(N=C1C1=C([H])C([H])=C([H])C([H])=C1[H])C(=NC1=C2C(=NN(C1=O)C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=NC([H])=C1[H])C([H])([H])[H]
[H]OC(=O)[C@@]1([H])C([H])([H])C([H])([H])[C@]([H])(C(=O)N2C([H])([H])C([H])([H])N(C3=C([H])C([H])=C(N([H])C(=O)C4=C(OC(=N4)C4=C([H])C([H])=C([H])C([H])=C4[H])C(F)(F)F)C([H])=C3[H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]OC1=C([H])C(OC([H])([H])[H])=C([H])C2=C1C(=O)C1=C(O[H])C([H])=C(C([H])=C1C2=O)C([H])([H])[H]
[H]OC1=C(N(C([H])([H])C(=O)C2=C([H])C([H])=C([H])C([H])=C2[H])S(=O)(=O)C2=C([H])C([H])=C([H])C([H])=C12)C(=O)OC([H])([H])C([H])([H])[H]
[H]N1C2=C(C([H])=C(C([H])=C2[H])C(=O)N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H])C(=C1C1=C([H])C(=C([H])C(=C1[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1=C([H])C([H])=NC([H])=C1[H]
[H]N(C(=O)OC([H])([H])C1(C([H])([H])OC2=C3SC([H])=C([H])C3=NC([H])=N2)C([H])([H])C([H])([H])C1([H])[H])[C@]([H])(C(=O)C(=O)N([H])[C@@]([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]N1C2=C([H])C([H])=C(C([H])=C2C([H])([H])C1=O)C1=C([H])C(=C([H])C([H])=C1[H])[N+]([O-])=O
[H]N(C(=O)C1=C([H])C([H])=C(F)C(=C1[H])C(F)(F)F)[C@](C1=NC([H])=C(Cl)C([H])=C1[H])(C1=C([H])C(OC(F)(F)C([H])(F)F)=C([H])C(F)=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C1=C([H])C(Cl)=C(OC2=C([H])C(=C(C#N)C([H])=C2[H])C(F)(F)F)C([H])=C1[H]
[H]N(C1=NC2=C(C([H])=C(C([H])=C2N=N1)C1=C(C([H])=C([H])C([H])=C1C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C(OC([H])([H])C([H])([H])[H])C([H])=C1[H]
[H]N(C1=NN2C(=N1)C([H])=NC([H])=C2C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)C([H])([H])[H])C1=C([H])C(=C([H])N=C1[H])N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N1C2=C(C([H])=C([H])C([H])=C2[H])C2=C1C([H])=C(OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])=C2[H]
[H]C1=C(OC(=N1)C(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C#CC1=C([H])C([H])=C([H])C(Cl)=C1Cl)C1=C([H])C([H])=C([H])C([H])=N1
[H]OC([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C(C([H])=C([H])C([H])=N2)C2=NC3=C([H])C(OC([H])([H])[H])=C([H])C(=C3C(=O)O2)C([H])([H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N(C(=O)N1C(=O)N(C2=C([H])C([H])=C([H])C([H])=C12)C1([H])C([H])([H])C1([H])[H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N(C([H])([H])C1=C([H])N(C2=C([H])C([H])=C([H])C([H])=C2C1=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])[C@]12C([H])([H])[C@@]3([H])C([H])([H])[C@]([H])(C([H])([H])[C@]([H])(C3([H])[H])C1([H])[H])C2([H])[H]
[H]OC(=O)C([H])([H])[C@@]([H])(N([H])C(=O)C([H])([H])N([H])C(=O)C1=C([H])C(N([H])C2=NC([H])([H])[C@@]([H])(O[H])C([H])([H])N2[H])=C([H])C(N([H])[H])=C1[H])C1=C([H])C(Cl)=C([H])C(I)=C1O[H]
[H]O[C@]1([H])[C@@]([H])(N([H])C([H])([H])C2=C([H])C([H])=C([H])C(=C2[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])S(=O)(=O)C([H])([H])[C@@]1([H])C([H])([H])C1=C([H])C([H])=C(N([H])[H])C(OC([H])([H])C(F)(F)F)=C1[H]
[H]N(C1=NC([H])=C([H])C(=N1)N(C(=O)OC1=C(C([H])=C([H])C([H])=C1C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1OC([H])([H])[H])C1=C([H])C(F)=C(OC([H])([H])C([H])([H])C([H])([H])N2C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C2([H])[H])C([H])=C1[H]
[H]N([H])C1=NC(=NC(=N1)C([H])([H])Cl)N([H])C1=C([H])C([H])=C([H])C(=C1C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1N([H])C(=O)C1=C([H])C([H])=C(C([H])=C1[H])N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C([H])([H])C1([H])[H]
[H]O[C@]1([H])C([H])([H])C2=C([H])C([H])([H])[C@@]3([H])[C@]4([H])C([H])([H])[C@]5([H])O[C@@]6(N([H])C([H])([H])[C@]([H])(C([H])([H])[H])C([H])([H])C6([H])[H])[C@@]([H])(C([H])([H])[H])[C@]5([H])[C@@]4(C([H])([H])[H])C([H])([H])C([H])([H])[C@]3([H])[C@@]2(C([H])([H])[H])C([H])([H])C1([H])[H]
[H]O[C@@]([H])(C(=O)N([H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])SC([H])=N1)[C@@]([H])(O[H])C(=O)N1C([H])([H])C([H])([H])C([H])([H])[C@]1([H])C1=C([H])C(Cl)=C([H])C([H])=C1[H]
[H]ON([H])C(=O)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(=O)N([H])C1=C([H])C([H])=C(N([H])C(=O)C([H])([H])[H])C([H])=C1[H]
[H]N([H])C1=NC2=C(N=NN2C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2N([H])[H])C(=N1)C1=C([H])C([H])=C([H])O1
[H]N1C2=C([H])C(=NN2[C@]([H])(C2=C([H])C3=C(C([H])=C([H])C([H])=C3[H])N2C([H])([H])[H])C(C(=O)N2C([H])([H])C([H])([H])C([H])([H])[C@@]2([H])C2=C([H])C(=NO2)C([H])([H])[H])=C1C([H])([H])OC([H])([H])[H])C(F)(F)F
[H]N(C(=O)C1=C([H])C([H])=C([H])C2=C1C([H])=C([H])C([H])=C2[H])C1=C(C#N)C2=C(S1)C([H])([H])C([H])([H])C([H])([H])C2([H])[H]
[H]O[C@]([H])(C1=C([H])C([H])=C(S1)S(=O)(=O)C1=C([H])C([H])=C([H])C([H])=C1[H])[C@]1([H])N(C(=O)C([H])([H])[C@]1([H])C1=C(OC([H])([H])[H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H]
[H]N([H])[C@]1([H])C(=O)N([H])C(=O)[C@](OC2=C([H])C([H])=C(OC3=C([H])C([H])=C(C([H])=C3[H])C3=NC([H])=C([H])O3)C([H])=C2[H])(C1=O)C([H])([H])C([H])([H])OC([H])([H])C([H])([H])[H]
[H]N(C(=O)C([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H])S(=O)(=O)C1=C([H])C([H])=C([H])C([H])=C1C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1C2=C(N=C1C([H])([H])C([H])([H])[H])C(=C([H])C(=N2)C([H])([H])[H])C([H])([H])[H]
[H]N1C2=C(C([H])=C1C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H])C(=O)N(C(=O)N2[H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C([H])C([H])=C([H])C([H])=C2OC([H])([H])[H])C([H])([H])C1([H])[H]
[H]N(C(=O)C#CC([H])([H])[H])C1=C(OC([H])([H])[H])C([H])=C2N=C([H])C(C#N)=C(N([H])C3=C([H])C(Br)=C([H])C([H])=C3[H])C2=C1[H]
[H]OC(=O)C1=C([H])C2=C([H])C(Cl)=C([H])C(C#C[H])=C2O[C@@]1([H])C(F)(F)F
[H]N([H])C(=O)C1=NN(C2=C1C([H])([H])C([H])([H])N(C1=C([H])C([H])=C(C([H])=C1[H])C1(C([H])([H])N(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H])C2=O)C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]OC1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[C@]([H])(N([H])[H])C(=O)N([H])[C@@]([H])(C(=O)N([H])C([H])([H])C(=O)N([H])[C@]([H])(C(=O)N(C([H])([H])[H])[C@]([H])(C(=O)N1C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)OC([H])([H])C1=C([H])C(=C([H])C(=C1[H])C(F)(F)F)C(F)(F)F)C([H])([H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H]
CCN(CC)C1=CC=C(CN(CC2=CC=CC=C2)S(=O)(=O)C2=CC=C(OC(C)C)C=C2)C=C1
[H]C(=O)C1=C([H])C([H])=C(OS(=O)(=O)C(\[H])=C(/[H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])=C1[H]
[H]N1C([H])=C(C2=C1C([H])=C([H])C([H])=C2[H])C1=C([H])C2=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C([H])=C2N=C1[H]
[H]N([H])[C@@]([H])(C(=O)N([H])C1=C([H])C2=C(C([H])=C1Cl)C(=O)N([H])C([H])=C2[H])C1=C([H])C([H])=C([H])C(Cl)=C1[H]
[H]N(C(=O)C([H])([H])N1C(=O)C2=C([H])C(OC([H])([H])C([H])([H])C([H])([H])N3C([H])([H])C([H])([H])C([H])([H])C([H])([H])C3([H])[H])=NN2C([H])=C1C1=C([H])C([H])=C(F)C(Cl)=C1[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]OC(=O)C([H])([H])[C@]([H])(N([H])C(=O)C([H])([H])[H])C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(OS(=O)(=O)O[H])C([H])=C1[H]
[H]N(OC([H])([H])[H])C(=O)C1=C(F)C([H])=C(F)C(N([H])C2=NC([H])=NN3C([H])=C(C4=NN=C(O4)C([H])([H])C4([H])C([H])([H])C4([H])[H])C(=C23)C([H])(C([H])([H])[H])C([H])([H])[H])=C1[H]
[H]OC(C([H])([H])[H])(C([H])([H])[H])C1([H])C([H])([H])C([H])([H])N(C2=C(C([H])=C(C([H])=N2)C2=C([H])N=NC3=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C([H])=C23)C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N(C(=O)C(\[H])=C(/[H])C1=C2N(C(=O)C(F)(F)C2=C([H])C([H])=C1[H])C([H])([H])C1=C([H])C(F)=C(F)C([H])=C1[H])S(=O)(=O)C1=C([H])C(Cl)=C(Cl)S1
[H]N(C(=O)C([H])([H])N1C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2N(C2([H])C([H])([H])C([H])([H])N(C([H])([H])C2([H])[H])[C@]2([H])C([H])([H])C([H])([H])[C@@]3([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@@]3([H])C2([H])[H])S1(=O)=O)C([H])([H])[H]
[H]N(C(=O)[C@]1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C(=O)N1C([H])([H])C([H])([H])N(C2=NC3=C(S2)C([H])=C([H])N=C3[H])C([H])([H])C1([H])[H])C1(C#N)C([H])([H])C1([H])[H]
[H]OC([H])([H])C([H])([H])N(C1=C(C#CC2=C([H])C([H])=C(F)C([H])=C2[H])C([H])=C2N([H])C(=O)C([H])([H])C(=NC2=C1[H])C1=C([H])C([H])=C([H])C(=C1[H])N1C([H])=NC([H])=C1[H])C([H])([H])[H]
[H]O[C@@]1([H])C([H])([H])[C@@]2([H])C([H])([H])C([H])([H])[C@]1(C([H])([H])S(=O)(=O)N1C([H])([H])C([H])([H])C(=C3C4=NC([H])=C([H])C([H])=C4C([H])([H])C([H])([H])C4=C3C([H])=C([H])C(Cl)=C4[H])C([H])([H])C1([H])[H])C2(C([H])([H])[H])C([H])([H])[H]
[H]OC1=C(C(=O)OC([H])([H])C([H])([H])[H])C([H])([H])N(C1=O)[C@]([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H]
[H]O[C@]1(C([H])([H])[H])C([H])([H])[C@]([H])(C2=NC(=C3N2C([H])=C([H])N=C3N([H])[H])C2=C(C([H])=C(C([H])=C2[H])C(=O)C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])[H])C1([H])[H]
[H]OC1=C([H])C([H])=C(\C([H])=C2/SC(=O)N(C2=O)C([H])([H])C(O[H])(O[H])C(F)(F)F)C([H])=C1[H]
[H]OC(=O)C([H])([H])C1=C([H])C([H])=C([H])C(N([H])C(=O)C2=C([H])C([H])=C(OC([H])([H])[C@@]3([H])OC4=C(C([H])=C([H])C([H])=C4[H])N(C([H])([H])[H])C3([H])[H])C([H])=C2C([H])([H])[H])=C1[H]
[H]C1=C([H])C(OC([H])([H])[H])=C2N=C(N(C2=C1[H])C1=NC(=NC(=C1[H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C([H])(F)F
[H]OC1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[C@]([H])(N([H])[H])C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])C([H])([H])C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])N([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])O[H])C([H])([H])C(=O)N([H])[H])C([H])([H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H])C([H])([H])C(=O)N([H])[H]
[H]N([H])C1=C(N([H])C(=O)C2=C([H])C([H])=C(C([H])=C2[H])C([H])(C(=O)N([H])C2=C([H])C(OC([H])([H])[H])=C([H])C([H])=C2[H])C(=O)N([H])C2=C([H])C([H])=C([H])C(OC([H])([H])[H])=C2[H])C([H])=C([H])C([H])=C1[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C(=C1C(=O)N(C(=O)C1([H])[H])C([H])([H])C#CC([H])([H])N1C([H])([H])C([H])([H])N(C2=C([H])C([H])=C([H])C([H])=C2OC([H])([H])[H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC(=O)C([H])([H])N([H])S(=O)(=O)C1=C([H])C([H])=C(N([H])C(=O)C([H])([H])[H])C([H])=C1[H]
[H]ON(C([H])=O)[C@@]([H])(C([H])([H])OC1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C(C#N)C([H])=C1[H])C([H])([H])C([H])([H])N1C(=O)N([H])C(C1=O)(C([H])([H])[H])C([H])([H])[H]
[H]C1=NC(=C([H])N=C1C([H])([H])[H])N1C([H])([H])C([H])([H])C([H])(C([H])([H])C1([H])[H])C1([H])C([H])([H])C([H])([H])N(C2=NC(=NC(=C2[H])C([H])([H])[H])C#N)C([H])([H])C1([H])[H]
Cc1cnc(N[C@H]2CCOC2)nc1-c1cc(C(=O)N[C@H](CO)c2ccccc2)n(C)c1
[H]N([H])C1=C(C([H])=C([H])C(=C1[H])C([H])([H])[H])N(C1=C([H])C([H])=C([H])C([H])=C1C([H])([H])N(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC(=O)C([H])([H])OC1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)OC([H])([H])C1([H])C2=C(C([H])=C([H])C([H])=C2[H])C2=C1C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C(=O)OC([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C(=O)C([H])([H])[C@]([H])(C(=O)N([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C1=C(N=C(S1)N1N=C(C2=C([H])C([H])=C(OC([H])([H])[H])C([H])=C2[H])C([H])([H])[C@]1([H])C1=C([H])C([H])=C(Br)C([H])=C1[H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]OC(=O)C([H])([H])N([H])C(=O)C([H])([H])[C@@]1([H])O[C@@]([H])(C2=C([H])C(Cl)=C([H])C([H])=C2N2C([H])=C([H])C([H])=C12)C1=C(OC([H])([H])[H])C(OC([H])([H])[H])=C([H])C([H])=C1[H]
[H]C1=NC([H])=C(N=C1[H])[C@@]([H])(C1=C(C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C#N)C([H])([H])C2=C([H])C([H])=C([H])C([H])=C12)C([H])([H])[H]
[H]C1=C([H])C2=C(C([H])=C1[H])C([H])([H])OC(=O)N2C1([H])C([H])([H])C([H])([H])N(C(=O)C2=C(OC([H])([H])[H])C([H])=C(OC3([H])C([H])([H])C([H])([H])N(C([H])([H])C4=C([H])C([H])=C([H])[N+]([O-])=C4C([H])([H])[H])C([H])([H])C3([H])[H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N1N(C2=NC(=O)C([H])([H])S[C@@]([H])(C2=C1C([H])([H])[H])C1=C([H])C2=C(OC([H])([H])O2)C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H]
[H]O[C@@]([H])(C([H])([H])[C@@]([H])(OC([H])([H])C([H])([H])[H])C(=O)N([H])[C@]([H])(C(=O)N([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])(C([H])([H])[H])C([H])([H])[H])[C@@]([H])(N([H])C(=O)C1=C([H])C(=C([H])C(=C1[H])C(=O)N([H])[C@@]([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H])N(C([H])([H])[H])S(=O)(=O)C([H])([H])[H])C([H])([H])OC1=C([H])C(F)=C([H])C(F)=C1[H]
[H]N(C1=C(C(=C([H])C([H])=C1[H])N(C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])C(OC([H])([H])[H])=C([H])C([H])=C1[H])C([H])([H])[H])S(=O)(=O)C([H])([H])[H]
[H]N(C1=C([H])C2=C(C([H])=C1SC1=C(F)C([H])=C(F)C([H])=C1[H])C(=O)C([H])([H])C2([H])[H])S(=O)(=O)C(F)(F)F
[H]N([H])C(=O)C1=NN(C2=C1C([H])=C([H])C1=C2C([H])=NN1[H])C1=C([H])C([H])=C(C([H])=C1[H])C(F)(F)F
[H]N(C(=O)C1=C([H])SC([H])=C1[H])[C@@]1([H])[C@]2([H])C([H])([H])[C@]([H])(C([H])([H])[C@]1([H])C([H])([H])C(\[H])=C(/[H])C([H])([H])C([H])([H])C([H])([H])C(=O)N([H])S(=O)(=O)C([H])([H])[H])C2(C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])C([H])=C(C#CC(=O)N(C([H])([H])[H])C2([H])C([H])([H])C([H])([H])N(C([H])([H])C3=C([H])C([H])=C([H])C([H])=C3[H])C([H])([H])C2([H])[H])C([H])=C1[H]
[H]N1C([H])=C(C2=C([H])C(F)=C([H])C([H])=C12)C1=C([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N2C(=O)C3=C(C([H])=C(C([H])=C3[H])C([H])([H])[H])C2=O)C([H])([H])C1([H])[H]
[H]N(C(=O)C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C(OC([H])([H])[H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H])C([H])([H])C1=NC2=C([H])C(F)=C([H])C([H])=C2C(=O)N1C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC([H])([H])[C@@]1([H])O[C@@]([H])(N2C([H])=NC3=C2N=C([H])N=C3SC([H])([H])C2=C([H])C([H])=C([H])C([H])=C2F)[C@]([H])(O[H])[C@]1([H])O[H]
[H]OC([H])([H])[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]1([H])N([H])C(=O)C([H])([H])C1([H])[H])C([H])([H])C1=C([H])N([H])C([H])=N1)C([H])([H])C1=C([H])N([H])C2=C([H])C([H])=C([H])C([H])=C12)C(=O)N([H])[C@]([H])(C(=O)N([H])[C@@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N1C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C(=O)N([H])[C@@]([H])(C(=O)N([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=N\C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])\N([H])C#N)C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=N\C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])\N([H])C#N
[H]C1=C(C2=C([H])C([H])=C([H])C([H])=C2N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C2=C(C([H])=C(OC([H])([H])[H])C(OC([H])([H])[H])=C2[H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]N(C(=O)N([H])C([H])([H])C([H])([H])OC([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC(N2C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])=C2C([H])=NN(C2=N1)C1([H])C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N(C(=O)N([H])C1=C(C2=C([H])C(Cl)=C([H])C([H])=C2N=C1[H])C1=C(C([H])=C([H])C([H])=C1[H])C([H])([H])[H])C1=C([H])C([H])=C(F)C([H])=C1F
[H]N([H])C1=NC([H])=NC(N2C([H])([H])C([H])([H])N(C(=O)N([H])C3=C([H])C([H])=C(OC([H])(C([H])([H])[H])C([H])([H])[H])C([H])=C3[H])C([H])([H])C2([H])[H])=C1\C([H])=N\OC([H])([H])C([H])([H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]C1=C([H])C(=C([H])O1)C1=C([H])N(C2=C([H])C([H])=C([H])C([H])=C12)C([H])([H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C2=C(C([H])=C(OC([H])([H])[H])C(OC([H])([H])[H])=C2[H])C([H])([H])C1([H])[H]
[H]OC(=O)C(\[H])=C(/[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)C1=NN(C(N2C([H])=C([H])C([H])=C2[H])=C1C([H])([H])[H])C1=C([H])C([H])=C(Cl)C([H])=C1Cl)C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]N1C(SC([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N(C(=O)C([H])([H])C2=C([H])C([H])=C(C([H])=C2[H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])=NC(=C1C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C#CC([H])([H])N1N=NC(=N1)C1=C([H])C([H])([H])C([H])([H])N(C([H])([H])[H])C1([H])[H]
[H]N(N(C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H])C(=O)C1=C(OC([H])([H])[H])C(=NC2=C([H])C([H])=C([H])C([H])=C12)C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC(=O)C([H])([H])N([H])C([H])([H])C([H])([H])N([H])C([H])([H])C(=O)N([H])N([H])C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)N([H])[H]
[H]OC(=O)[C@@]([H])(OC([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(OC([H])([H])C2=NOC(=N2)C2=C([H])C([H])=C(C([H])=C2[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])=C1[H]
[H]OC([H])([H])[C@@]1([H])O[C@@]([H])(N2C([H])=NC3=C(N=C([H])N=C23)N([H])[C@@]2([H])C3=C(C(OC([H])(C([H])([H])[H])C([H])([H])[H])=C([H])C([H])=C3[H])C([H])([H])C([H])([H])C2([H])[H])[C@]([H])(O[H])[C@]1([H])O[H]
COC1=CC(C)=C(C(C)=C1)S(=O)(=O)N(C)CCOCC(=O)N(C)CC1=CC=C(C=C1)C1=NCCN1
[H]N=C(N([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N([H])C(=O)C([H])([H])N1C(=O)C(=NC(Cl)=C1C1=C([H])C([H])=C([H])C([H])=C1[H])N([H])C([H])([H])C([H])([H])C([H])([H])N([H])[H]
[H]N1C([H])=C(C2=C1C([H])=C([H])C(F)=C2[H])C([H])([H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])N2C3=C(C([H])=C([H])C([H])=C3[H])C3(C2=O)C([H])([H])C3([H])[H])C([H])([H])C1([H])[H]
[H]N(C(=O)C1=C([H])C([H])=NC([H])=C1[H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C([H])C([H])=C([H])C([H])=C2OC([H])([H])[H])C([H])([H])C1([H])[H]
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[H]N(C(=O)C1=C([H])C([H])=C([H])C([H])=C1F)C1=C(C#N)C2=C(S1)C([H])([H])C([H])([H])C([H])([H])C2([H])[H]
COC1=CC2=C(CN(C[C@]3(NC(=O)NC3=O)C#CC3=CC(=CC=C3)C(=NO)N3CCN(C)CC3)C2=O)C=C1
[H]C1=C([H])C2=C(C([H])=C1[H])C(=O)C(N1C(=O)C([H])([H])C([H])([H])C1=O)=C(Cl)C2=O
[H]N([H])C1=NC(N([H])[H])=C2C(=N1)N([H])C(SC1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])=C2C([H])(C([H])([H])[H])C([H])([H])[H]
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[H]C1=C([H])C(OC([H])([H])[H])=C(C([H])=C1[H])N1C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C2=C([H])C([H])=C([H])C(OC([H])([H])C([H])([H])OC([H])([H])C([H])([H])OC3=C([H])C([H])=C([H])C(=C3[H])C([H])([H])C([H])([H])N3C([H])([H])C([H])([H])N(C4=C([H])C([H])=C([H])C([H])=C4OC([H])([H])[H])C([H])([H])C3([H])[H])=C2[H])C([H])([H])C1([H])[H]
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[H]OC1=C([H])C(=C(C(=C1[H])C([H])([H])[H])C([H])([H])[C@]([H])(N([H])[H])C(=O)N([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1=NC(=C(N([H])C1=O)C([H])([H])[H])C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C([H])C2=C([H])C([H])=C([H])C([H])=C12)C1=C(C#N)C2=C(S1)N(C([H])([H])C1=C([H])C([H])=C([H])N=C1[H])C([H])([H])C([H])([H])C2([H])[H]
[H]N([H])C1=N[C@@](C(=O)N1C([H])([H])[H])(C1=C([H])SC(=C1[H])C([H])([H])C([H])([H])[H])C1=C([H])C(=C([H])C([H])=C1[H])C1=C([H])N=C([H])N=C1[H]
[H]N([H])C(=O)N([H])C1=C([H])C([H])=C2N([H])C(=O)\C(=C(/C3=C([H])C(=C([H])N3[H])C([H])([H])N([H])C(=O)C([H])([H])C([H])([H])N3C([H])([H])C([H])([H])C([H])([H])C([H])([H])C3([H])[H])C([H])([H])[H])C2=C1[H]
CCCCN(C)C(=O)CC1=C(N=C2N1C=CC=C2Cl)C1=CC(=C(Cl)C=C1)N(O)=O
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[H]N(C(=O)C1=C([H])C([H])=C(C#N)C(OC([H])([H])C([H])([H])[H])=N1)C([H])([H])C1=C([H])C(OC([H])([H])[H])=C([H])C([H])=C1OC([H])([H])[H]
[H]C1=NC(=NC([H])=C1[H])N1C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])C([H])([H])N2C(Cl)=C([H])OC3=C([H])C([H])=C([H])C([H])=C3C2=O)C([H])([H])C1([H])[H]
[H]N1C(=O)C2=C(C1=O)C1=C([H])N(C3=C1C([H])=C([H])C([H])=C3[H])C([H])([H])C([H])([H])C([H])([H])C1=C(N=C(C([H])=C1[H])C([H])([H])C([H])([H])N1C([H])=C2C2=C1C([H])=C([H])C([H])=C2[H])N(C([H])([H])[H])C([H])([H])[H]
[H]OC(=O)C1=C(C([H])=C2C([H])=C([H])C([H])=C([H])C2=C1[H])N1C([H])([H])C([H])([H])N(C(=O)C2=NC(C3=C([H])C([H])=C(C([H])=C3[H])C([H])([H])[H])=C(C([H])=N2)C2=C([H])C([H])=C(OC([H])([H])[H])C([H])=C2[H])C([H])([H])C1([H])[H]
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COC1=CC=C2C=C(CNCCC3=CC=C(Br)C=C3)C(=NC2=C1)C1=NC=CO1
CN1C=CC(C)=C(C1=O)C1=CC=C(C[C@H](NC(=O)C2=C(Cl)C=CC=C2Cl)C(O)=O)C=C1
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[H]N(C(=O)OC([H])(C([H])([H])[H])C([H])([H])[H])C1=NC([H])=C(SC([H])([H])C2=NC([H])=C(O2)C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])S1
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[H]ON([H])C(=O)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N([H])C([H])([H])C1=C([H])C(OC([H])([H])[H])=C([H])C([H])=C1[H]
[H]C1=C([H])C([H])=C(C(OC([H])([H])[H])=C1[H])C([H])([H])N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C(=O)C1=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C([H])=C1[H]
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[H]C1=C([H])C(C(=O)C2=C([H])N(C(=O)C3=C(C([H])=C([H])C([H])=C3[H])S([O-])(=O)=O)C3=C2C([H])=C([H])C(=C3[H])C2=C([H])C([H])=C(F)C([H])=C2[H])=C2N1[C@]([H])(SC2([H])[H])C1=C([H])N=C([H])C([H])=C1[H]
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[H]N([H])S(=O)(=O)C1=C([H])C([H])=C(C([H])=C1[H])C(=O)N([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)N([H])[H]
[H]N(C1=NC([H])=C(C(=O)N([H])C([H])([H])C2([H])C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])C(=N1)C(F)(F)F)C1=C(F)C(F)=C([H])C([H])=C1[H]
[H]N(C(=O)C1=NC(=NO1)C1=C([H])N=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C([H])C(=C([H])C(=C2[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N(C([H])([H])C([H])([H])OC1=C([H])C(F)=C([H])C2=C1OC([H])([H])C([H])([H])[C@@]2([H])OC([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]N=C(N([H])[H])C1=C([H])C(=C([H])C([H])=C1[H])C1=NO[C@@](C(=O)N([H])C2=NC([H])=C(C([H])=N2)C2=C([H])C([H])=C([H])C([H])=C2S(=O)(=O)N([H])[H])(C([H])([H])OC([H])([H])C([H])([H])[H])C1([H])[H]
[H]N([H])C(=O)C1=C(SC(=C1C([H])([H])[H])C([H])([H])[H])N([H])C(=O)C1=C([H])C([H])=C(Cl)S1
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[H]N=C(N([H])[H])N([H])C(=O)C1=C([H])C2=C(C#N)C([H])=C([H])C([H])=C2S1
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[H]N([H])C([H])([H])C([H])([H])C(=O)N([H])C1=NC([H])=C(SC([H])([H])C2=NC([H])=C(O2)C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])S1
[H]N([H])C1=C2C(=NC([H])=N1)N(N=C2C1=C([H])C2=C(N([H])C(=N2)C([H])([H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])=C1[H])[C@@]1([H])C([H])([H])C([H])([H])[C@]([H])(N2C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
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[H]S\C(=N\C([H])([H])C1=C([H])SC(=N1)C1=C([H])C([H])=C(C([H])=C1[H])C(F)(F)F)N1C([H])([H])C([H])([H])N(C2=NC([H])=NC3=C([H])C(OC([H])([H])C([H])([H])C([H])([H])N4C([H])([H])C([H])([H])C([H])([H])C([H])([H])C4([H])[H])=C(OC([H])([H])[H])C([H])=C23)C([H])([H])C1([H])[H]
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[H]N(C1=NC2=C(C([H])=C([H])C([H])=C2C2=NN=C([H])N2[H])C2=C([H])N=C([H])C([H])=C12)C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]C1=C([H])C(=C([H])C([H])=C1C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C([H])([H])[H]
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[H]O[C@@]([H])(C1=C([H])C(OC([H])([H])[H])=C(Br)C([H])=C1OC([H])([H])[H])[C@@]([H])(N([H])[H])C([H])([H])[H]
[H]OC1=C([H])C(=C([H])C([H])=C1[H])C([H])([H])C([H])([H])OC1=C2C([H])=[N+]3C(=C([H])C2=C([H])C([H])=C1OC([H])([H])[H])C1=C(C([H])=C2OC([H])([H])OC2=C1[H])C([H])([H])C3([H])[H]
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[H]OC1=C([H])C([H])=C(C2=C1N([H])C(=O)C([H])=C2[H])[C@@]([H])(O[H])C([H])([H])N([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])(OC2=NN(C3=C2C([H])([H])C([H])([H])C([H])([H])C3([H])[H])C2=C(F)C([H])=C([H])C([H])=C2O[H])C([H])([H])C1([H])[H]
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[H]OC([H])([H])C([H])([H])N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])N(C(=O)N([H])C1=C([H])C(Cl)=C(F)C([H])=C1[H])[C@]1([H])C([H])([H])C([H])([H])[C@]2(C3=C([H])C([H])=C([H])C(C#N)=C3[H])C([H])([H])[C@]2([H])C1([H])[H]
[H]O[C@]1([H])N(C(=N[H])N([H])[H])C([H])([H])C([H])([H])C([H])([H])[C@]1([H])N([H])C(=O)C([H])([H])N1C(=O)[C@@]([H])(N([H])S(=O)(=O)C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C1([H])[H]
[H]N1N=C(C(=C1C1=NC([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=NC2=C1C([H])=C([H])C([H])=C2[H])C1([H])C([H])([H])C1([H])[H]
[H]N1C(=NC2=C([H])C(Cl)=C([H])C([H])=C12)C([H])([H])C1=NC(=C([H])C(=O)N1[H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]OC1=C([H])C([H])=C([H])C(=C1[H])C1=NC(N2C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])=C2N=C([H])N([H])C2=N1
CC1=NN2C(C1)C1=C(OCC2=O)C(Br)=CC(Br)=C1
[H]C1=NC(=NC([H])=C1F)N1C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])[C@@]([H])(OC(=O)C([H])([H])[H])C2=C([H])C([H])=C(F)C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C([H])C(=C1[H])C(F)(F)F)C1=C([H])C([H])=C([H])C(=C1[H])C1=C([H])C([H])=NC2=C(C([H])=NN12)C(=O)N([H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H]
[H]OC(=O)[C@@]([H])(N([H])C(=O)[C@@]1([H])N(C([H])([H])C([H])([H])C1([H])[H])S(=O)(=O)C1=C([H])C(Cl)=C([H])C(Cl)=C1[H])C([H])([H])C1=C([H])C([H])=C(OC(F)(F)F)C([H])=C1[H]
[H]N=C(N([H])[H])N([H])C([H])([H])C([H])([H])C([H])([H])[C@]([H])(N([H])C(=O)[C@@]1([H])N2N(C([H])([H])C1([H])[H])C([H])([H])C([H])([H])[C@@](N([H])[H])(C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C2([H])[H])C([H])([H])Cl
[H]N(C1=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C(OC([H])([H])[H])=C1[H])C1=C(C#N)C([H])=NC2=C([H])C(C#CC([H])([H])C([H])([H])N3C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C3([H])[H])=C(OC([H])([H])[H])C([H])=C12
[H]N([H])[C@@]1([H])C([H])([H])N(C2=C([H])C3=C(N(N=C3C([H])=C2[H])C([H])(C([H])([H])[H])C([H])([H])[H])S(=O)(=O)C2=C3C([H])=C([H])C([H])=C([H])C3=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C(Cl)C([H])=C1[H])C1=C([H])C([H])=C([H])N=C1[H]
[H]N([H])C1=NC2=C(N=C(N([H])C3=C([H])C([H])=C([H])C([H])=C3[H])C([H])=C2[H])C(=N1)N([H])[H]
[H]N=C(N([H])[H])N([H])C([H])([H])C([H])([H])C([H])([H])[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C1=C([H])C([H])=C([H])O1)C([H])([H])C1=C([H])C([H])=C(Cl)C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C(=O)N([H])[C@]([H])(C(=O)N([H])[H])C([H])([H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H]
[H]OC(=O)C([H])([H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1C([H])([H])C([H])([H])C1=C([H])N=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])N([H])S(=O)(=O)C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])OC([H])([H])[C@]([H])(C1=C([H])C([H])=C(Cl)C(Cl)=C1[H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])[C@]2(C3=C([H])C([H])=C([H])C([H])=C3[S@@](=O)C2([H])[H])C([H])([H])C1([H])[H]
[H]N(C(=O)N([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C2=C(N=C(C3=C([H])C([H])=C([H])O3)C(=N2)C2=C([H])C([H])=C([H])O2)C([H])=C1[H]
[H]N1C(=O)N([H])C2=C(C1=O)C(=C([H])C(=O)O2)C([H])([H])C(=O)OC([H])([H])C([H])([H])[H]
[H]OC(=O)C([H])([H])[C@]([H])(N([H])C(=O)[C@@]([H])(C([H])([H])C(=O)N([H])C([H])([H])C([H])([H])C1=C2C([H])=C([H])C([H])=NC2=C([H])C([H])=C1[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])=O
[H]N(C(=O)[C@@]([H])(N([H])C(=O)OC([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])N([H])C1=C([H])C([H])=C(OC2([H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C2([H])[H])C([H])=C1[H]
[H]C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])SC([H])([H])C(=O)C(F)(F)F
[H]OC(=O)C([H])([H])[C@]1([H])C2=C(C([H])=C([H])C(=C2[H])C([H])([H])[H])[C@@]2(C1([H])[H])C([H])([H])C([H])([H])N(C(=O)N([H])[C@@]1([H])[C@@]3([H])C([H])([H])[C@]4([H])C([H])([H])[C@]([H])(C3([H])[H])C([H])([H])[C@@]1([H])C4([H])[H])C([H])([H])C2([H])[H]
[H]N([H])C(=O)C1=C2N([H])C3=C(C([H])=C([H])C(=C3[H])C3=C([H])N(N=C3[H])C([H])([H])[H])C2=C(N([H])[C@@]([H])(C([H])([H])[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])=C1[H]
[H]OC1=C([H])C([H])=C(C([H])=C1Cl)C(=O)N([H])\N=C(/[H])C1=C([H])C([H])=C(OC([H])([H])C(=O)N2C([H])([H])C3=C(C([H])=C([H])C([H])=C3[H])C([H])([H])C2([H])[H])C2=C([H])C([H])=C([H])C([H])=C12
[H]N1C([H])=C(C(=O)C(=O)N2C([H])([H])C([H])([H])N(C(=O)C3=C([H])C([H])=C([H])C([H])=C3[H])C([H])([H])[C@@]2([H])C([H])([H])[H])C2=C([H])C([H])=C([H])C([H])=C12
[H]C1=C([H])C([H])=C(S1)N(C(=O)O[C@@]1([H])C([H])([H])[C@@]2([H])N(C([H])([H])[H])[C@]([H])(C([H])([H])C2([H])[H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N1N=NC(=N1)C1=C([H])C([H])=C(OC([H])([H])C([H])([H])C([H])([H])C([H])([H])OC2=C([H])C([H])=C3N(C([H])=C([H])C3=C2C([H])([H])C([H])([H])C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])=C1[H]
[H]N1C([H])=C(C2=C([H])C(C#N)=C([H])C([H])=C12)C1=C([H])C([H])([H])[C@]([H])(N2C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]OC1=C([H])C([H])=C(OC([H])([H])[C@@]([H])(O[H])C([H])([H])N([H])C([H])([H])C2([H])C([H])([H])C([H])([H])N(C([H])([H])C2([H])[H])S(=O)(=O)C2=C([H])C([H])=C(N([H])C(=O)N([H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])=C2[H])C([H])=C1[H]
[H]N([H])C1(C([H])([H])[C@@]([H])(C(=O)N2C([H])([H])C([H])([H])N(C3=NC([H])=NC4=C3[C@@]([H])(SC4([H])[H])C([H])([H])[H])C([H])([H])C2([H])[H])C([H])([H])C2=C([H])C([H])=C(Cl)C(F)=C2[H])C([H])([H])C1([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C(N2C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C(=C1[H])C(F)(F)F)C1=C([H])C([H])=C([H])C(OC([H])([H])C([H])([H])[H])=C1[H]
[H]N(C(=O)N([H])C1=C([H])C([H])=C([H])N(C1=O)C([H])([H])C1=C(Cl)C([H])=C([H])C([H])=C1[H])C1=C([H])C(F)=C([H])C([H])=C1[H]
[H]OC1=C([H])C(=C([H])C(O[H])=C1O[H])C(=O)OC1=C([H])C(=C([H])C(O[H])=C1O[H])C(=O)OC([H])([H])[C@@]1([H])O[C@]([H])(OC(=O)C2=C([H])C(O[H])=C(O[H])C(OC(=O)C3=C([H])C(O[H])=C(O[H])C(O[H])=C3[H])=C2[H])[C@@]([H])(OC(=O)C2=C([H])C(O[H])=C(O[H])C(OC(=O)C3=C([H])C(O[H])=C(O[H])C(O[H])=C3[H])=C2[H])[C@]([H])(OC(=O)C2=C([H])C(O[H])=C(O[H])C(OC(=O)C3=C([H])C(O[H])=C(O[H])C(O[H])=C3[H])=C2[H])[C@@]1([H])OC(=O)C1=C([H])C(O[H])=C(O[H])C(OC(=O)C2=C([H])C(O[H])=C(O[H])C(O[H])=C2[H])=C1[H]
[H]N(C1=NC(C2=C([H])N=C3C([H])=C([H])C([H])=C([H])N23)=C(OC([H])([H])[H])C([H])=N1)C1=C([H])C([H])=C(C([H])=C1OC([H])([H])[H])N1C([H])([H])C([H])([H])N(C(=O)C([H])([H])[H])C([H])([H])C1([H])[H]
[H]OC1([H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C2=C([H])C([H])=C(C([H])=C2[H])N2C([H])=C(C3=C(N=C([H])N=C23)N([H])[H])C2=C([H])C(OC([H])([H])[H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C([H])C2=C1N([H])C([H])=C2[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=NSC3=C2C([H])=C([H])C([H])=C3[H])C([H])([H])C1([H])[H]
[H]N(C1=NC([H])=C(SC2=C([H])C(C(=O)N3C([H])([H])C([H])([H])N(C(=O)C([H])([H])[H])C([H])([H])C3([H])[H])=C(C([H])=C2[H])C([H])([H])[H])S1)C1=NC([H])=C([H])C([H])=C1[H]
[H]N(C(=O)C1=C([H])C2=C([H])C([H])=C([H])C([H])=C2N1C([H])([H])C1=NOC(=C1[H])C1=C([H])C([H])=C(Cl)C([H])=C1[H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N1C(=O)C2(C3=C(C([H])=C(F)C([H])=C3[H])C1([H])[H])C([H])([H])C([H])([H])N(C([H])([H])C2([H])[H])[C@@]1([H])C([H])([H])C([H])([H])[C@@]([H])(C([H])([H])C1([H])[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]N([H])C(=O)[C@@]12C([H])([H])[C@@]3([H])C([H])([H])[C@@]([H])(C1([H])[H])[C@@]([H])(N([H])C(=O)[C@@]1([H])SC([H])([H])C([H])([H])N1S(=O)(=O)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H])[C@]([H])(C3([H])[H])C2([H])[H]
[H]N(C(=O)C1=C(N([H])C(=O)C2=C(Cl)C(=C([H])S2)C([H])([H])N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H])C(OC([H])([H])[H])=C([H])C(Cl)=C1[H])C1=NC([H])=C(Cl)C([H])=C1[H]
[H]N(C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[C@@]1(C(=O)N(C2=C([H])C([H])=C([H])C([H])=C2[H])C2=C([H])C([H])=C([H])C([H])=C2C1([H])[H])C([H])([H])[H]
[H]N(C(=O)C1=NC([H])=C([H])C(OC2=C([H])C([H])=C3N([H])C(=NC3=C2[H])N([H])C2=C([H])C(=C([H])C([H])=C2[H])C(F)(F)F)=C1[H])C([H])([H])[H]
[H]N([H])C1=NC(=O)\C(N1[H])=C1\C2=C(N([H])C(Br)=C2Br)C(=O)N([H])[C@]([H])(C([H])([H])[H])C1([H])[H]
[H]N(C(=O)C1=NN(C2=C1C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C1=C([H])N=C(N=C21)N([H])C1=C([H])C(=C([H])C([H])=C1[H])N(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])[H]
[H]O[C@]([H])(C([H])([H])N([H])C1([H])C([H])([H])C1([H])[H])[C@@]([H])(N([H])C(=O)C1=C([H])C(=C([H])C(=C1[H])N(C([H])([H])[H])S(=O)(=O)C([H])(C([H])([H])[H])C([H])([H])[H])C(=O)N([H])[C@@]([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)C([H])([H])N(C([H])([H])[H])[C@]1([H])C([H])([H])C([H])([H])[C@]([H])(O[C@@]([H])(C2=C([H])C(=C([H])C(=C2[H])C(F)(F)F)C(F)(F)F)C([H])([H])[H])[C@@]1([H])C1=C([H])C([H])=C(F)C([H])=C1[H])C([H])([H])C([H])([H])OC([H])([H])[H]
[H]C1=C([H])[C@]2([H])N([C@@]1([H])C([H])([H])[C@@]([H])(OC1=C(C(OC3=C([H])C([H])=C([H])N=C3C([H])([H])[H])=NC([H])=N1)C([H])([H])[H])C2([H])[H])S(=O)(=O)C1([H])C([H])([H])C1([H])[H]
[H]N([H])S(=O)(=O)C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C(O1)C(\[H])=C(\C#N)C1=NC2=C([H])C([H])=C([H])C([H])=C2S1
[H]OC1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])[C@]([H])(N([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C(O[H])C(O[H])=C1[H])C([H])([H])[H]
[H]N1C(=O)N(C(=O)C2=C1C([H])=NC([H])=C2[H])C([H])([H])C([H])([H])N1C([H])([H])[C@@]2([H])C3=C([H])C([H])=C([H])C(OC([H])([H])[H])=C3C([H])([H])C([H])([H])[C@@]2([H])C1([H])[H]
[H]N(C(=O)N([H])[C@@]([H])(C(=O)N1C([H])([H])C([H])([H])C([H])(C(=O)C2=C([H])C([H])=C(F)C([H])=C2[H])C([H])([H])C1([H])[H])C([H])([H])OC([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C(=C([H])C([H])=C1[H])C([H])([H])[H]
[H]OC1=C(F)C([H])=C2C(=C1[H])C([H])([H])[C@@]([H])(N([H])[H])[C@]2([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N([C@]1([H])C(=O)N(C([H])([H])C(=O)N2C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C([H])([H])C1([H])[H])S(=O)(=O)C(\[H])=C(/[H])C1=C([H])C([H])=C(Cl)S1
CC1=CC=CC(=C1)C(C1=CC=NC=C1)C1=CC2=C3N(CCC3=C1)C(=O)CC2
[H]N1C([H])([H])[C@@]([H])(N(C(=O)OC([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])[C@]([H])(C([H])([H])[H])C1([H])[H])C([H])([H])[H]
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[H]C1=C([H])C([H])=C(O1)C([H])([H])N1C([H])=C(C(=O)N=C1SC([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])N=C([H])N=C1[H]
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[H]C1=C([H])C(=C([H])N1S(=O)(=O)C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H]
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[H]N(C(=O)OC1=C([H])C([H])=C([H])C(=C1[H])C([H])([H])N(C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])OC1=C([H])C2=C(C([H])=C1[H])C(=O)C1=C([H])C([H])=C([H])C([H])=C1O2)C([H])([H])[H]
[H]OC([H])([H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])OC2=C([H])C3=NC([H])=NC(N([H])C4=NN([H])C(=C4[H])C([H])([H])C(=O)N([H])C4=C([H])C([H])=C([H])C([H])=C4[H])=C3C([H])=C2OC([H])([H])[H])C([H])([H])C1([H])[H]
[H]N=C(SC([H])([H])C([H])([H])[H])N([H])C1=C(Br)C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)C1([H])C([H])([H])N(C([H])([H])[H])C1([H])[H])[C@]([H])(C1=NC([H])=C(N1[H])C1=NC2=C([H])C([H])=C([H])C([H])=C2N=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C(=O)C([H])([H])[H]
[H]N(C1=NC([H])([H])C2=C1C([H])([H])N(C(=O)N([H])[C@]1([H])C([H])([H])[C@@]1([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C2(C([H])([H])[H])C([H])([H])[H])C1=C([H])C(=NC(=N1)C([H])([H])[H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])(OC([H])([H])C([H])([H])N1C([H])([H])[C@@]2([H])N(C([H])([H])[H])[C@]([H])(C([H])([H])C2([H])[H])C1([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]O[C@@](C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1F)(C([H])([H])C(C1=C([H])C(F)=C([H])C([H])=C1OC([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C(F)(F)F
[H]N([H])C1=NC(=C(C([H])=C1[H])C([H])([H])N([H])C(=O)[C@]1([H])C([H])=C([H])C([H])([H])N2N1C(=O)N(C2=O)[C@@]([H])(C(=O)OC([H])([H])C([H])([H])[H])C([H])([H])SC1=C([H])C(Cl)=C(Cl)C([H])=C1[H])C([H])([H])[H]
[H]N1C([H])([H])C([H])([H])[C@]([H])(N(C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])S(=O)(=O)C2=C([H])C3=C([H])C([H])=C([H])C([H])=C3C([H])=C2[H])C1([H])[H]
[H]C1=C([H])C([H])=C(O1)[C@@]1([H])OC([H])([H])[C@]([H])(O1)C([H])([H])[N+]1(C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
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[H]N(C1=NC([H])=C([H])C(=N1)C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H])C1([H])C([H])([H])C([H])([H])N([H])C([H])([H])C1([H])[H]
[H]C1=C(OC2=C([H])C([H])=C(C([H])=C12)C([H])([H])C([H])([H])C([H])([H])OC(=O)[C@@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])[H])C1=C([H])C([H])=C2OC([H])([H])OC2=C1[H]
[H]O[C@@]1(C([H])([H])[H])C([H])([H])[C@]([H])(C2=NC(=C3N2C([H])=C([H])N=C3N([H])[H])C2=C([H])C([H])=C(O[C@@]3([H])OC([H])([H])C([H])([H])C([H])([H])C3([H])[H])C([H])=C2[H])C1([H])[H]
[H]N([H])C(=O)C1(N2C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C([H])([H])N(C(=O)C2=C([H])C(=C(N2C([H])([H])C([H])([H])C([H])([H])N([H])S(=O)(=O)C([H])([H])[H])C2=C([H])C([H])=C(Cl)C([H])=C2[H])C2=C([H])C([H])=C(Cl)C([H])=C2Cl)C([H])([H])C1([H])[H]
[H]C1=C([H])C(OC([H])([H])[H])=C(C([H])=C1[H])N1C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])C([H])([H])OC2=C([H])C([H])=C([H])C3=C2C2=C([H])C([H])=C([H])C4=C2[C@@]([H])(N(C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C4([H])[H])C3([H])[H])C([H])([H])C1([H])[H]
[H]OC(=O)C([H])([H])C([H])([H])C(=O)N1C2=C([H])C([H])=C(C([H])=C2C([H])([H])C1([H])[H])C1=NOC(=N1)C1=C([H])C(=C(C([H])=C1[H])C([H])([H])C([H])([H])[H])C(F)(F)F
[H]N([H])C1=NC([H])=C(C([H])=N1)C1=NC2=C(SC(=C2C([H])([H])[H])C2=C([H])C([H])=C([H])C(=C2[H])C(=O)N2C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C2([H])[H])C(=N1)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]OC(=O)C([H])([H])C([H])([H])[C@]([H])(N([H])C(=O)C1=C([H])C(OC2([H])C([H])([H])C([H])([H])N([H])C([H])([H])C2([H])[H])=C([H])C(=N1)C1=C([H])C([H])=C([H])C([H])=C1[H])C(=O)N1C([H])([H])C([H])([H])N(C(=O)OC([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]OC1=C([H])C(O[H])=C(C([H])=C1C1=C(N([H])C(=O)C2=NC(=C(S2)C2=C([H])C([H])=C(F)C([H])=C2[H])C([H])([H])[H])C(=NO1)C(=O)N([H])C([H])([H])C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)N1C([H])([H])C([H])([H])C([H])(N2C([H])([H])C([H])([H])C([H])(OC3=C([H])C(Cl)=C(Cl)C([H])=C3[H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H])S(=O)(=O)C1=C([H])C([H])=C(C([H])=C1[H])N(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C3=C([H])C([H])=C([H])C([H])=C3C([H])=C2[H])C([H])([H])C1([H])[H]
[H]OC([H])([H])C(C([H])([H])[H])(C([H])([H])[H])[C@@]1([H])N([H])C2=C([H])C([H])=C(C([H])=C2[C@@]([H])(N([H])C(=O)N([H])C([H])(C([H])([H])[H])C([H])([H])[H])C1([H])[H])[N+]([O-])=O
[H]N([H])S(=O)(=O)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N([H])S(=O)(=O)[C@]1([H])O[C@]([H])(C(=O)OC([H])([H])[H])[C@]([H])(OC(=O)C([H])([H])[H])[C@]([H])(OC(=O)C([H])([H])[H])[C@@]1([H])OC(=O)C([H])([H])[H]
[H]O[C@]1(C2=NC3=C(O2)C([H])=C([H])C([H])=C3[H])C([H])([H])[N@]2C([H])([H])C([H])([H])[C@]1([H])C([H])([H])C2([H])[H]
[H]N(C(=O)[C@@]1([H])C([H])([H])C([H])([H])[C@@]2(OC(=O)C3=C([H])C([H])=NC([H])=C23)C([H])([H])C1([H])[H])C1=NC([H])=C(C([H])=N1)C1=C([H])C([H])=C([H])C([H])=C1F
CC1=NC(C(=O)N2CCC[C@H]2CC2=NN=C(O2)C2=CC=CC=C2)=C(S1)C1=C(F)C=CC=C1
[H]C1=C([H])C(=C(C2=C([H])C([H])=C3OC([H])([H])[C@@]([H])(N(C([H])([H])[H])C([H])([H])[H])C([H])([H])C3=C2[H])C(=C1[H])C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)N(C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C2N=C(N(C(=O)C2=C1[H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1F)C1=C([H])C([H])=C([H])C([H])=C1S(=O)(=O)N([H])C(=O)OC([H])([H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]OC([H])([H])[C@]([H])(N([H])C(=O)C([H])([H])N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)C([H])([H])N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])[H])C([H])([H])C([H])([H])SC([H])([H])[H])[C@]([H])(O[H])C([H])([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])[C@@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])N([H])C([H])=N1)C([H])([H])C(=O)N([H])[H])C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])C([H])([H])C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])C([H])([H])C(=O)N1C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C(=O)N1C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C(=O)N([H])C([H])([H])C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[H])C([H])([H])C([H])([H])C([H])([H])N=C(N([H])[H])N([H])[H])C([H])([H])O[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C(=O)N([H])[H])C([H])([H])C([H])([H])C([H])([H])N=C(N([H])[H])N([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C(=O)N([H])[H])C([H])([H])C([H])([H])C([H])([H])N=C(N([H])[H])N([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C(=O)N([H])[H])C([H])([H])[H]
[H]C1=C(N=C(N1C1=C([H])C([H])=C2OC([H])([H])C([H])([H])OC2=C1[H])C1=C([H])C([H])=C(F)C([H])=C1[H])C(=O)N1C([H])([H])C([H])([H])N(C2=C([H])N=C3C([H])=C([H])C([H])=C([H])C3=C2[H])C([H])([H])C1([H])[H]
[H]O[C@@]1(C(=O)OC([H])([H])C2=C1C([H])=C1N(C2=O)C([H])([H])C2=C([H])C3=C([H])C(OC([H])([H])C([H])([H])N([H])C(=O)C4=NC(N([H])C(=O)C([H])([H])C([H])([H])C([H])([H])[H])=C([H])N4C([H])([H])OC([H])([H])[H])=C([H])C([H])=C3N=C12)C([H])([H])C([H])([H])[H]
[H]C1=C(SC(=C1[H])C1=C([H])C([H])=C(C([H])=C1OC([H])([H])[H])C(=O)N1C([H])([H])[C@]2(C([H])([H])[H])C([H])([H])[C@@]1([H])C([H])([H])C(C([H])([H])[H])(C([H])([H])[H])C2([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
OC(=O)C1=CC(OCC2CCN(CC2)C2=NC=C(NC(=O)C3=CC=C(OC4=CC=CC=C4)C=C3)C=C2)=CC=C1
[H]C1=C([H])C2=C(C(=N1)N1C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])[C@@]3([H])C([H])([H])C([H])([H])[C@]([H])(C([H])([H])C(=O)C4=C([H])C([H])=C(C([H])=C4[H])N4C([H])([H])C([H])([H])C([H])([H])C([H])([H])C4([H])[H])C([H])([H])C3([H])[H])C([H])([H])C1([H])[H])C([H])([H])C([H])([H])O2
[H]N1C2=C([H])C([H])=C(Br)C([H])=C2[C@]([H])(N(C([H])([H])C(=O)OC([H])([H])C([H])([H])[H])[C@@]1([H])C1=C([H])C([H])=C(F)C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
CCSc1nnc2N(CCCn12)C(=O)CN1CCOCC1
[H]C1=C([H])C2=C(C([H])=C([H])C([H])=C2[H])N1C(=O)O[C@@]1([H])C([H])([H])[N@]2C([H])([H])C([H])([H])[C@]1([H])C([H])([H])C2([H])[H]
[H]OC1=C(C2=C([H])C([H])=C([H])C([H])=C2C(=O)N1C([H])([H])C1=C([H])C([H])=C(F)C([H])=C1[H])S(=O)(=O)C([H])(C([H])([H])[H])C([H])([H])[H]
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[H]OC1=C([H])\C(=N\C2=C3C([H])=C(OC([H])([H])[H])C(OC([H])([H])C([H])([H])C([H])([H])N4C([H])([H])C([H])([H])C([H])([H])C4([H])[H])=C([H])C3=NC([H])=N2)C(=O)C([H])=C1OC([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)C1=C([H])C(C#CC2=C([H])N=C3C([H])=C([H])C([H])=NN23)=C(C([H])=C1[H])C([H])([H])[H])C1=C([H])C(=C([H])C([H])=C1[H])C(F)(F)F
[H]N(C(=O)N([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=NC2=C1N=C([H])N2[H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]N([H])C([H])([H])C([H])([H])OC1=C([H])C(N([H])C2=C([H])N=C([H])C(=N2)C2=C([H])C(N([H])C(=O)C([H])([H])[H])=C([H])C([H])=C2[H])=C([H])C([H])=C1[H]
[H]N1C(=O)C2=C([H])C([H])=C([H])C3=C2N(C([H])=C3\C([H])=N/OC([H])([H])[H])C([H])([H])C1([H])[H]
[H]N1C([H])([H])C([H])([H])C([H])(C([H])([H])C(=O)N2C([H])([H])C([H])([H])C(=C3C4=C(C([H])=C([H])C([H])=N4)C([H])([H])SC4=C3C([H])=C([H])C(Cl)=C4[H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
CC1=C(Cl)C(C)=C2C(N)=C(SC2=N1)C(=O)NCC1=CC=NC=C1
[H]O[C@]12C([H])([H])C3=C(O[C@]1(C([H])([H])[H])C([H])([H])C([H])([H])[C@@]1(O[H])C(C([H])=C([H])C(=O)[C@]21C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])=C(OC3=O)C1=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]N1N=C(C2=C(C3=C([H])C(OC([H])([H])[H])=C([H])C(=C3N=C12)C([H])([H])[H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])[C@]([H])(C1([H])[H])C(F)(F)F)C([H])([H])[H]
[H]N1C([H])([H])C(=O)N(C2=C([H])C([H])=C(OC([H])([H])C([H])([H])C([H])([H])OC([H])([H])C3=C(OC([H])([H])[H])C([H])=C([H])C([H])=C3[H])C([H])=C2[H])[C@@]([H])(C([H])([H])OC([H])([H])C2=C([H])N=C([H])C([H])=C2[H])C1([H])[H]
[H]N1C(=O)S[C@]([H])(C1=O)C1=C([H])C([H])=C(OC([H])([H])C([H])([H])C([H])([H])OC2=C(C([H])=C(OC3=C([H])C([H])=C([H])C([H])=C3[H])C([H])=C2[H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])=C1[H]
[H]N(C(=O)C1=C(N(C(=N1)C([H])([H])[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C([H])C([H])=C([H])C(Cl)=C2C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N(C(=O)C([H])([H])[H])C1=NC2=C(C([H])=C([H])C([H])=C2[H])C2=C([H])N(N=C12)C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]N(C1=C2C(=NC3=C1C([H])=C([H])C([H])=C3[H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])C1=C2C(=NC3=C1C([H])=C([H])C([H])=C3[H])C([H])([H])C([H])([H])C2([H])[H]
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[H]N(C1=NC(=C(C([H])=N1)C1=NC(=C([H])N1[H])C([H])([H])[H])C1=C(Cl)C([H])=C(Cl)C([H])=C1[H])C([H])([H])C([H])([H])N([H])C1=C([H])C([H])=C(C#N)C([H])=N1
[H]OC(=O)C([H])([H])OC1=C([H])C([H])=C2N([H])C3=NC(O[H])=NC3=C([H])C2=C1[H]
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[H]N(C(=O)C1=C([H])C([H])=C(O1)C1=C([H])C([H])=C(Cl)S1)C1=C([H])C([H])=C(C([H])=C1[H])N1C([H])([H])C([H])([H])N([H])C([H])([H])C1([H])[H]
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[H]O[C@]([H])(C([H])([H])[C@@]([H])(C(=O)N([H])C([H])([H])[C@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)C([H])(C([H])([H])C1=C2C([H])=C([H])C([H])=C([H])C2=C([H])C([H])=C1[H])C([H])([H])C1=C2C([H])=C([H])C([H])=C([H])C2=C([H])C([H])=C1[H])C([H])([H])C1=C([H])N([H])C([H])=N1)C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N([H])N1C(SC([H])([H])C([H])([H])C([H])([H])N2C([H])([H])C([H])([H])N(C3=C([H])C([H])=C([H])C([H])=C3OC([H])([H])[H])C([H])([H])C2([H])[H])=NC2=C(C([H])=C([H])C([H])=C2[H])C1=O
[H]N([H])C1=NC(N([H])[H])=C2C3=C(C([H])=C([H])C2=N1)N(C([H])=C3[H])C([H])([H])C1=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C(OC([H])([H])[H])=C1[H]
[H]N=C(N([H])[H])N([H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N([H])C(=O)N1C([H])([H])C([H])([H])N(C(=O)N([H])C([H])([H])C2=C([H])C3=C([H])C([H])=C([H])C([H])=C3C([H])=C2[H])C([H])([H])C1([H])[H]
[H]C1=C([H])C(C(=O)C2=C([H])C([H])=C(C([H])=C2[H])C(=O)C([H])([H])[H])=C2OC([H])([H])[C@]([H])(N(C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C2=C1[H]
[H]C1=C([H])C2=C(OC3([H])C([H])([H])C([H])([H])N(C([H])([H])C4=NC([H])=C([H])N=C4[H])C([H])([H])C3([H])[H])N=C([H])N=C2N1C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C1=C(C2=NN(N=N2)C([H])([H])[H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N(C(=O)C([H])([H])N1C2=C(C([H])=C([H])C([H])=C2[H])C(=N[C@@]([H])(C1=O)C([H])([H])OC(=O)N([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C(\[H])=C(/[H])C(=O)OC([H])([H])[H]
[H]ON([H])C(=O)C1(N([H])S(=O)(=O)C2=C([H])C([H])=C(OC3=C([H])C([H])=C([H])C(Cl)=C3[H])C([H])=C2[H])C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]N(C(=O)C1=C(C([H])=C([H])C([H])=C1[H])C1=NN([H])N=N1)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1C(=NN=C1C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])[S@](=O)C([H])([H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]N(C(=O)N([H])[C@]12C([H])([H])[C@@]3([H])C([H])([H])[C@]([H])(C([H])([H])[C@]([H])(C3([H])[H])C1([H])[H])C2([H])[H])[C@@]1([H])C([H])([H])C([H])([H])[C@]([H])(OC2=C([H])C(F)=C([H])C(F)=C2[H])C([H])([H])C1([H])[H]
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[H]O[C@]([H])(C1=C([H])C([H])=C(S1)S(=O)(=O)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])[C@]1([H])N(C(=O)C([H])([H])[C@]1([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H]
[H]N(C1=NC2=C([H])C(=C(C([H])=C2N=N1)C1=C([H])C(F)=C([H])C([H])=C1C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C(OC([H])([H])C([H])([H])N2C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])=C1[H]
[H]N(C(=O)C1=C([H])C(OC([H])([H])[H])=C([H])C(OC([H])([H])[H])=C1[H])C([H])([H])C1(C(=O)OC([H])([H])[H])C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C3=C(OC2(C([H])([H])[H])C([H])([H])[H])C([H])=C([H])C([H])=C3[H])C([H])([H])C1([H])[H]
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[H]OC(=O)C([H])([H])C1=NN(C(=O)C2=C1C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C1=C([H])C([H])=C(Br)C([H])=C1F
[H]N(C(=O)C([H])([H])[C@]1([H])N(C([H])([H])C([H])([H])N([H])C1=O)S(=O)(=O)C1=C([H])C([H])=C(Cl)C([H])=C1[H])[C@@]1([H])C2=C(C([H])=C(C([H])=C2[H])C([H])([H])N2C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C([H])([H])C1([H])[H]
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[H]N(N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C(=O)C1=C([H])N(C(=N1)C1=C([H])C([H])=C(Cl)C([H])=C1Cl)C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]OC(=O)[C@]([H])(OC1=C([H])C(=C([H])C([H])=C1[H])C([H])([H])N(C1=NC2=C(O1)C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C([H])([H])OC1=C([H])C([H])=C([H])C(=C1[H])[N+]([O-])=O)C([H])([H])C([H])([H])[H]
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[H]C1=C([H])C([H])=C2N=C(SC2=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]N1C([H])([H])C([H])([H])C([H])(N(C(=O)C([H])([H])C([H])([H])C2=C([H])C(=C([H])C(=C2[H])C(F)(F)F)C(F)(F)F)C([H])([H])C2=C([H])C([H])=C(F)C([H])=C2[H])C([H])([H])C1([H])[H]
[H]OC(=O)[C@]([H])(N1C([H])([H])[C@]([H])(C2=C([H])C(F)=C([H])C([H])=C2[H])[C@@]([H])(C([H])([H])N2C([H])([H])C([H])([H])C([H])(C([H])([H])C([H])([H])C(F)(F)C3=C([H])C([H])=C(F)C([H])=C3[H])C([H])([H])C2([H])[H])C1([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]ON(C([H])=O)C([H])([H])[C@]([H])(C(=O)N([H])C([H])([H])C(=O)OC([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]O[C@]([H])(C([H])([H])[H])[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)C([H])([H])N([H])[H])C([H])([H])C(=O)N([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H])C([H])([H])[H])C(=O)N([H])C([H])([H])C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[H])C([H])([H])C([H])([H])SC([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])N([H])C([H])=N1
[H]ON([H])C(=O)C([H])([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])C([H])([H])C([H])([H])C(=O)N([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H]
[H]N(C1=C(C2=C(N([H])C([H])=C2[H])C([H])=C1[H])C([H])([H])[H])C1=C2C([H])=C(SC2=NC([H])=C1C#N)C1=C(OC([H])([H])C([H])([H])[H])C([H])=C([H])C(=C1[H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H]
[H]OC([H])([H])C1=NN=C(S1)C1=NN=C(C([H])=C1[H])N1C([H])([H])C([H])([H])C([H])(OC2=C([H])C([H])=C([H])C([H])=C2C(F)(F)F)C([H])([H])C1([H])[H]
[H]C1=C([H])C([H])=C(S1)C(=O)N1C([H])([H])C([H])([H])C([H])(N2C(=O)C([H])([H])C([H])([H])C3=C2C([H])=C([H])C([H])=C3[H])C([H])([H])C1([H])[H]
[H]N([H])C1=C([H])C([H])=C([H])C([H])=C1N([H])C(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N1C(=O)C2=C([H])C([H])=C([H])C3=C([H])C([H])=C([H])C(C1=O)=C23
[H]OC1=C(O[H])C([H])=C(\C([H])=C(/C#N)C(=O)N([H])C2=C([H])C([H])=C([H])C([H])=C2Cl)C([H])=C1[H]
[H]C1=C([H])C([H])=C2N(C(=S)SC2=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]O[C@]([H])(C([H])([H])N([H])C([H])([H])C1=C([H])C(=C([H])C([H])=C1[H])N(C([H])([H])[H])C([H])([H])[H])[C@@]([H])(N([H])C(=O)[C@@]1([H])N([H])C(=O)N(C([H])([H])C2=C([H])C(OC([H])([H])[H])=C([H])C(OC([H])([H])[H])=C2[H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N([H])C1=C([H])N=C(N(C1=O)C([H])([H])C(=O)N([H])[C@@]([H])(C(=O)C1=NC2=C(O1)C([H])=C([H])C(=C2[H])C(=O)OC([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C(=C([H])C([H])=C1[H])[N+]([O-])=O
[H]OC(=O)[C@]1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C(=O)N([H])C([H])([H])C1=C([H])C([H])=C([H])C(=C1[H])N1N=C(C([H])=C1N([H])C(=O)N([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]O[C@@]([H])(C([H])([H])[H])[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)C([H])([H])C([H])([H])C([H])([H])N=C(N([H])[H])N([H])[H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])[N+]([O-])=O)C(=O)N([H])[C@]([H])(C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC1=C([H])C([H])=C(C2=C1N([H])C(=N2)C1=C([H])C([H])=C([H])O1)C([H])([H])[H]
[H]N(C1=C(C(=NO1)C([H])([H])[H])C([H])([H])[H])S(=O)(=O)C1=C(C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1C2=C(N=C1C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])=C([H])C(OC([H])([H])[H])=C2[H]
[H]N([H])C1=C([H])N=C(N([H])C(=O)C2=C([H])C([H])=C(C([H])=C2[H])C(F)(F)F)C([H])=C1[H]
COC1=CC=C(CNC(=O)NC2=CC=C(C=C2)C2=CNN=C2)C(OC)=C1
[H]OC(=O)[C@@]([H])(N([H])C(=O)OC([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C(=O)N1C([H])([H])C([H])([H])C2(C(=O)N(C3=C([H])C([H])=C(C([H])=C3[H])C(=N[H])N([H])[H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
O[C@H]1[C@@H](O)[C@@H](O[C@@H]1COS(=O)(=O)O[Na])N1C=NC2=C1N=C(Cl)N=C2NC1CCCCC1
[H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1C2=NC3=C(N2C([H])([H])C([H])([H])C1([H])[H])C(=O)N(C(=O)N3C([H])([H])[H])C([H])([H])[H]
[H]N(C1=NC(=NC(=N1)N1C([H])([H])C([H])([H])N([H])C([H])([H])C1([H])[H])N([H])C1([H])C([H])([H])C2=C(C([H])=C([H])C([H])=C2[H])C1([H])[H])C1=C([H])C([H])=C([H])N=C1[H]
[H]C1=C(N(C(=C1[H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C(OC([H])([H])[H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H])C([H])([H])[H])C([H])([H])N(C(=O)C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1=C([H])C([H])=NC([H])=C1[H])C([H])([H])[C@]([H])(C1=C(N([H])C2=C1C([H])=C(C([H])=C2[H])C(C(=O)N1C([H])([H])C([H])([H])C2(OC([H])([H])C([H])([H])O2)C([H])([H])C1([H])[H])(C([H])([H])[H])C([H])([H])[H])C1=C([H])C(=C([H])C(=C1[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])[H]
[H]OC1=C([H])C(=C([H])C([H])=C1OC([H])([H])[H])C1=C(N=C([H])O1)C1=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C(OC([H])([H])[H])=C1[H]
[H]N([H])C(=O)[C@@]([H])(N([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N(\N=C1/C(=O)N([H])C2=C1C([H])=C(C([H])=C2[H])S(=O)(=O)N([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C(=O)C([H])([H])C1=C([H])C([H])=C2OC([H])([H])OC2=C1[H]
[H]N(C1=NC([H])([H])C2=C1C([H])([H])N(C(=O)N([H])[C@@]1([H])C([H])([H])[C@]1([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C2(C([H])([H])[H])C([H])([H])[H])C1=NC(=NC(Cl)=N1)C([H])([H])[H]
OC(=O)CCC1=CC=C(OCC2=CC(=CC=C2)C#N)C=C1
[H]OC1=C(C(=O)C([H])([H])S(=O)(=O)N([H])C2=NC3=C(S2)C([H])=C(C([H])=C3[H])S(=O)(=O)C([H])([H])[H])S(=O)(=O)N=C2SC3=C([H])C(=C([H])C([H])=C3N12)S(=O)(=O)C([H])([H])[H]
NS(=O)(=O)C1=CC=C(CCN2S(=O)(=O)C3=CC=CC=C3S2(=O)=O)C=C1
[H]N(C(=O)C([H])([H])OC1=C([H])C([H])=C(C([H])=C1[H])C(=O)C([H])([H])[H])[C@@]([H])(C([H])([H])N(C(=O)C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1OC([H])([H])[H])C([H])([H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H]
[H]\C(=C(\[H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C(=O)N1N=C(C2=C1C([H])([H])[C@]1([H])[C@@]2([H])C1(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])C(=C([H])C([H])=C1I)C(=O)O[C@@]1([H])C([H])([H])[C@@]2([H])N(C([H])([H])[H])[C@]([H])(C([H])([H])C2([H])[H])[C@@]1([H])C([H])([H])OC(=O)C([H])([H])[H]
[H]N([H])C(=NC(=O)C1=C([H])C([H])=C(O1)C1=C([H])C(=C([H])C(=C1[H])C([H])([H])[H])C([H])([H])[H])N([H])[H]
[H]OC([H])([H])[C@]1(OC(=O)\C(=C(/[H])C2=C([H])C([H])=C(OC([H])([H])[H])C([H])=C2[H])C1([H])[H])C([H])([H])OC(=O)C1=C([H])C([H])=C(C([H])=C1[H])N(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)N([H])[C@@]1([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C3C([H])=C(F)C([H])=C([H])C3=C2[H])C([H])([H])C1([H])[H])C1=C(OC([H])([H])C(=O)N(C([H])([H])[H])C([H])([H])[H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)C([H])([H])C([H])([H])N1[C@@]2([H])C([H])([H])C([H])([H])[C@]1([H])C([H])([H])[C@@]([H])(OC([H])(C1=C([H])C([H])=C(Cl)C([H])=C1[H])C1=C([H])C([H])=C(Cl)C([H])=C1[H])C2([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N([H])C1=NC(N([H])[H])=C2C([H])=C(C([H])=NC2=N1)C([H])([H])N(C1=C([H])C(Cl)=C(Cl)C(Cl)=C1[H])C([H])([H])[H]
[H]N=C(N([H])[H])C1=C([H])C(F)=C(C([H])=C1[H])C([H])([H])N([H])C(=O)C([H])([H])N1C([H])=C([H])C([H])=C(N([H])S(=O)(=O)C2=C([H])C([H])=C([H])C(OC([H])([H])[H])=C2[H])C1=O
[H]C1=C([H])C([H])=C(C([H])=C1[H])N([C@]([H])(C1=C(OC([H])([H])C([H])([H])C([H])([H])N2C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H])S(=O)(=O)C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC(=O)C([H])([H])[C@]([H])(N([H])C(=O)C([H])([H])C([H])([H])C(=O)N([H])C1=C([H])C([H])=C(C([H])=C1[H])C(=N[H])N([H])[H])C([H])=C([H])[H]
[H]C1=C([H])C(=C([H])C([H])=C1F)C1=C(C(=O)OC([H])([H])[H])[C@]2([H])O[C@@]([H])(C([H])([H])C2([H])[H])C1([H])[H]
[H]OC(=O)C(=C(/C(=O)C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])C([H])([H])C1=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C(OC([H])([H])[H])=C1[H])\C1=C([H])C(OC([H])([H])[H])=C2OC([H])([H])OC2=C1[H]
[H]C1=NC2=C(C3=C(S2)C([H])([H])N(C([H])([H])[H])C([H])([H])C3([H])[H])C(=O)N1C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C(OC([H])([H])[H])C([H])=C(Cl)C(Cl)=C2[H])C([H])([H])C1([H])[H]
[H]OC([H])([H])C([H])([H])N1N=NC(=N1)C1=C([H])C([H])=C(OC([H])([H])C2=C(C([H])=C([H])C([H])=C2[H])C([H])([H])[H])C([H])=C1[H]
[H]OC(=O)C([H])([H])N1C(=S)S\C(=C(\[H])C2=NOC(=C2[H])C2=C([H])C([H])=C(C([H])=C2[H])C([H])([H])[H])C1=O
[H]O[C@]([H])(C([H])([H])N([H])C(=O)C1=C(N(C(=N1)C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1Cl)C([H])([H])[H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C([H])C([H])=C([H])C(=C2C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H]
CN(CC(=O)N[C@@H](CCCCN)B(O)O)C(=O)C1=CC=CC=C1
[H]N([H])[C@]([H])(C(=O)N1C([H])([H])C2=C(C([H])=C([H])C([H])=C2[H])C1([H])[H])C([H])([H])C(=O)N1C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C(C([H])=C2[H])C2=C([H])C([H])=C([H])C([H])=C2C#N)C([H])([H])C1([H])[H]
[H]C1=C(N=C(S1)C1=C(C([H])=NC([H])=C1[H])C([H])([H])[H])C1=C([H])N=C([H])C([H])=C1[H]
[H]OC(=O)C([H])([H])N([H])S(=O)(=O)C1=C([H])C2=C(N([H])C(=O)\C2=C(\[H])C2=C([H])N(C3=C2C([H])=C(OC([H])([H])[H])C([H])=C3[H])C([H])([H])[H])C([H])=C1[H]
[H]N(C(=O)OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])[C@@]([H])(C([H])=O)[C@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])[H]
[H]C1=C([H])C(OC([H])([H])[H])=C([H])C2=C1N(C(=O)C1=C([H])C([H])=C(Cl)C([H])=C1[H])C(=C2C([H])([H])C(=O)OC1=C([H])C([H])=C(SC([H])([H])[H])C([H])=C1[H])C([H])([H])[H]
[H]ON([H])C(=O)[C@@]1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])OC2=C([H])C([H])=C(C([H])=C2[H])C([H])([H])[C@]([H])(N([H])C(=O)[C@]1([H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C(=O)C1=C([H])C([H])=C([H])C([H])=C1[H]
COC(=O)CC1=C(C)N(C(=O)C2=CC=C(C)C=C2)C2=CC=C(OC)C=C12
[H]N([H])C1=NC2=C(C([H])=C(N2[H])C([H])([H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C(=N1)N([H])C1=C(F)C([H])=C(Cl)C([H])=C1[H]
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[H]OC1=C2C([H])=C([H])C(=NC2=NC([H])=C1C(=O)N([H])C([H])([H])C1=C([H])C([H])=C(F)C([H])=C1[H])C([H])([H])[H]
[H]N([H])[C@@]([H])(C([H])([H])C(=O)N1C([H])([H])C([H])([H])[C@]([H])(N([H])C(=O)[C@@]1([H])C([H])([H])[H])C([H])([H])C([H])([H])[H])C([H])([H])C1=C(F)C([H])=C(F)C(F)=C1[H]
[H]OC1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[C@]([H])(N([H])[H])C(=O)N([H])C([H])([H])C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H]
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[H]OC1=C(C([H])=C([H])C2=C1C(=O)C1=C(OC([H])([H])[H])C([H])=C([H])C([H])=C1C2=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]C1=C(Cl)C([H])=C(Cl)C(=C1[H])C1=C2N=C(N=C(N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C2=NN1C([H])([H])[H])C([H])([H])[H]
[H]N1C2=C([H])C([H])=C([H])C([H])=C2C(C(=O)C(=O)N(C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])=C1C1=C([H])C([H])=C(C([H])=C1[H])C(F)(F)F
[H]OC1=C([H])C([H])=C(N([H])C(=O)C([H])([H])C([H])([H])C2=C([H])C([H])=C(N([H])C(=O)C3=C([H])C([H])=C([H])C([H])=C3O[H])C([H])=C2[H])C([H])=C1O[H]
[H]N(C(=O)C(N([H])C1=NN([H])C(=C1[H])C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])[C@@]([H])(C([H])([H])[H])[C@]([H])(C1=C([H])C(C#N)=C([H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]C1=C([H])N2C(=N1)C([H])([H])[C@@]([H])(C1=C(C([H])=C([H])C(F)=C1[H])C1=C([H])N=C([H])N=C1[H])C2([H])[H]
[H]N(C(=O)N([H])C([H])([H])C1=NC2=C([H])C([H])=C([H])C([H])=C2C(=O)N1C1=C([H])C(OC([H])(C([H])([H])[H])C([H])([H])[H])=C([H])C([H])=C1[H])C1=C([H])C(=C([H])C([H])=C1[H])C([H])([H])[H]
[H]N(C1=NN=C(SC([H])([H])C2=C([H])C([H])=C([H])O2)N1[H])C1=C([H])C([H])=C([H])C([H])=C1C([H])(C([H])([H])[H])C([H])([H])[H]
[H]OC(=O)C1=C([H])N([H])C(=N1)C(\[H])=C(\C1=C(C([H])=C2C(=C1[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C([H])([H])C2(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)C1=C(Br)C([H])=C(OC([H])([H])[H])C(OC([H])([H])[H])=C1[H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N([H])[C@@]([H])(C([H])([H])C(=O)N1C([H])([H])C([H])([H])N2C(=O)OC([H])([H])[C@]2([H])C1([H])[H])C([H])([H])C1=C([H])C(F)=C(F)C([H])=C1F
[H]OC([H])([H])[C@@]([H])(N([H])C(=O)[C@]1(N(C(=O)O[C@@]2([H])[C@@]3([H])C([H])([H])[C@]4([H])C([H])([H])[C@]([H])(C3([H])[H])C([H])([H])[C@@]2([H])C4([H])[H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC(=O)[C@]([H])(N([H])C(=O)[C@@]1([H])N(C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@]([H])(N([H])C(=O)[C@]([H])(N([H])C(=O)[C@]([H])(N([H])C(=O)C([H])([H])[H])C([H])([H])C2=C([H])C3=C([H])C([H])=C([H])C([H])=C3C([H])=C2[H])C([H])([H])C2=C([H])C([H])=C(Cl)C([H])=C2[H])C([H])([H])C2=C([H])N=C([H])C([H])=C2[H])C([H])([H])O[H])C([H])([H])C2=C([H])C([H])=C(N([H])C(=O)[C@@]3([H])N([H])C(=O)C([H])([H])C3([H])[H])C([H])=C2[H])C([H])([H])C2=C([H])C([H])=C(N([H])C(=O)N([H])[H])C([H])=C2[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])[H]
[H]OC([H])([H])[C@]([H])(N([H])C(=O)C([H])([H])N([H])C(=O)C([H])([H])OC([H])([H])C([H])([H])OC([H])([H])C([H])([H])N([H])C(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1=NN=NN1[H])C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]1([H])C(=O)N2C([H])([H])[C@]([H])(O[H])C([H])([H])[C@@]2([H])C(=O)N([H])[C@@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=O)C([H])([H])C1([H])[H])C([H])([H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=N[H])N([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=N[H])N([H])[H])C([H])([H])C1=C([H])N=C([H])N1[H])C([H])([H])C([H])([H])C(=O)N([H])[H]
[H]C1=C(N(N=C1C([H])([H])OC1=C([H])C(OC([H])([H])[H])=C([H])C(OC([H])([H])[H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@]1([H])C(=O)OC([H])([H])C([H])([H])C([H])([H])C1=C(OC([H])([H])[H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])[C@]12C([H])([H])[C@@]3([H])C([H])([H])[C@]([H])(C([H])([H])[C@]([H])(C3([H])[H])C1([H])[H])C2([H])[H]
[H]N(C(=O)N1C([H])([H])C([H])([H])C([H])(C2=NC(=NO2)C2=C([H])C([H])=NC([H])=C2[H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C([H])C([H])=C1OC([H])([H])[H]
[H]O\C([H])=C1\C(=O)C([H])=C2C(=C([H])[C@]3([H])[C@]4([H])C([H])([H])[C@@]([H])(C([H])([H])[H])[C@@]5(OC([H])([H])O[C@@]55OC([H])([H])OC5([H])[H])[C@]4(C([H])([H])[H])C([H])([H])[C@]([H])(O[H])[C@@]3([H])[C@]2(C([H])([H])[H])C1([H])[H])C([H])([H])[H]
[H]N(C(=O)C([H])([H])C([H])([H])C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C(N2C(=C1[H])N(C([H])=C(C(=O)N([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C2=O)C([H])([H])C1=C(F)C([H])=C([H])C([H])=C1[H])C([H])([H])N(C([H])([H])[H])C([H])([H])C([H])([H])C1=NC([H])=C([H])C([H])=C1[H]
[H]N(C(=O)C1=C([H])C(=C([H])C([H])=C1[H])C(F)(F)F)C1=C([H])C(N([H])C(=O)C2=C([H])N=C([H])C([H])=C2[H])=C(C([H])=C1[H])C([H])([H])[H]
[H]N1C([H])=C([H])N=C1C([H])([H])N1C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])C2=C([H])N([H])C3=C([H])C([H])=C(C([H])=C23)N2C([H])=NN=C2[H])C([H])([H])C1([H])[H]
[H]C1=C([H])C(=C([H])C(OC2=C([H])C([H])=C(C([H])=C2[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])=C1[H])C([H])([H])C([H])([H])C([H])([H])[C@@]([H])(P([O-])([O-])=O)S([O-])(=O)=O
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[H]N(C1=NC(=NN1C(=O)C1=C([H])C([H])=C(C([H])=C1[H])[N+]([O-])=O)C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N([H])C1=NC(=C([H])C(=N1)C1=C(Cl)C([H])=C(Cl)C([H])=C1OC([H])([H])C([H])([H])C([H])([H])C(F)(F)F)C([H])([H])[H]
[H]N(C(=O)C1=C2OC([H])([H])C([H])([H])N(C2=C([H])C(Cl)=C1[H])C([H])([H])[H])C([H])([H])[C@@]1([H])N(C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C1([H])[H]
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[H]N(C(=O)N([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC2=C(SC([H])=C2[H])C(=N1)C1=C([H])C([H])([H])OC([H])([H])C1([H])[H])C1=C([H])N=C([H])C([H])=C1[H]
[H]N([H])C1=NC(N(C(=N1)N([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)C1=C([H])N(N=C1[H])C([H])([H])[H])C([H])([H])C1=C(N(C2=C([H])C([H])=C([H])C([H])=C2[H])C2=C([H])C(Cl)=C([H])C([H])=C2C1=O)C(=O)N(C([H])([H])[H])C([H])([H])[H]
[H]N([H])S(=O)(=O)C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])N(N=N1)[C@]1([H])O[C@]([H])(C([H])([H])OC(=O)C([H])([H])[H])[C@@]([H])(O[C@@]2([H])O[C@]([H])(C([H])([H])OC(=O)C([H])([H])[H])[C@@]([H])(OC(=O)C([H])([H])[H])[C@]([H])(OC(=O)C([H])([H])[H])[C@@]2([H])OC(=O)C([H])([H])[H])[C@]([H])(OC(=O)C([H])([H])[H])[C@@]1([H])OC(=O)C([H])([H])[H]
[H]C1=C([H])C(=C([H])C([H])=C1Cl)S(=O)(=O)OC1=C([H])C([H])=C2C(OC(=O)C(=C2C([H])([H])[H])C([H])([H])[H])=C1[H]
[H]N(C(=O)C([H])([H])[H])C1=NC2=C([H])C([H])=C(C([H])=C2S1)C1=C([H])C([H])=NC(OC([H])([H])C2=C([H])C(F)=C([H])C([H])=C2[H])=N1
[H]OC([H])([H])C([H])([H])ON([H])C(=O)C1=C(N([H])C2=C([H])C([H])=C(I)C([H])=C2F)C(F)=C(F)C(=C1[H])C([H])([H])N([H])OC([H])([H])C([H])([H])[S@](=O)C([H])([H])[H]
[H]N1N=NC(=N1)C1=C(C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1C(=NC2=C1C(=O)N(C([H])=C2[H])[C@@]([H])(C(=O)N(C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
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[H]N([H])C(=O)C1=C([H])C2=C(S1)C([H])=NC([H])=C2SC([H])([H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
OC1=CC(Cl)=C(C=C1)C1=CC=C(S1)C1=CC=C(O)C=C1Cl
[H]N(C1=C([H])C(OC([H])([H])[H])=C(Cl)C([H])=C1Cl)C1=C(C#N)C([H])=NC2=C([H])C(\C([H])=C(/[H])C3=C([H])C([H])=[N+]([O-])C([H])=C3[H])=C(OC([H])([H])[H])C([H])=C12
[H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])OC1=NC2=C([H])C(Cl)=C([H])C([H])=C2N=C1N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H]
[H]OC(=O)C1=C([H])C([H])=C(C([H])=C1N([H])C([H])(C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])N([H])C([H])([H])[C@]([H])(O[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
CCCCCC(=O)OC1=C2CN3CCC4=CC5=C(OCO5)C=C4C3CC2=CC=C1OC
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[H]C([H])([H])C([H])([H])OC(=O)N1C([H])([H])C([H])([H])N(C(=O)C([H])([H])C([H])([H])[C@@]([H])(C(=O)N2C([H])([H])C([H])([H])C([H])([H])[C@@]2([H])C#N)[N+]([H])([H])[H])C([H])([H])C1([H])[H]
[H]O[C@@](C1=C([H])N([H])C([H])=N1)(C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]\C(=C(\[H])C1=C([H])C([H])=C(F)C([H])=C1F)C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N([H])C1=C(OC2=C([H])C([H])=C(OC([H])([H])C([H])([H])F)C([H])=C2C([H])([H])N(C([H])([H])[H])C([H])([H])[H])C([H])=C([H])C(=C1[H])C([H])([H])[H]
[H]N=C(N([H])[H])C1=C([H])C(OC2=C(N([H])C(=O)C3=C([H])C([H])=C(C([H])=C3[H])C3=C([H])C([H])=C([H])C([H])=C3S(=O)(=O)N([H])[H])C([H])=C([H])C(OC([H])([H])[H])=C2[H])=C([H])C([H])=C1[H]
[H]N1C([H])=NC(=C1[H])C([H])([H])C([H])([H])C([H])([H])OC([H])([H])C([H])([H])C([H])([H])[H]
[H]N(C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C(OC([H])([H])[H])C([H])=C([H])C(F)=C1[H])S(=O)(=O)C1=C([H])C(Cl)=C([H])C([H])=C1Cl
[H]N(C(=O)C1=C(N([H])C(=O)C2=C([H])C([H])=C(C([H])=C2[H])N2C(=O)C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C(OC([H])([H])[H])=C([H])C(Cl)=C1[H])C1=NC([H])=C(Cl)C([H])=C1[H]
[H]N(\C(N([H])[C@]1([H])C(=O)N(C([H])([H])C(=O)N2C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])=C(\C#N)C(=O)OC([H])([H])[H])C1=C([H])C([H])=C([H])C2=C1N([H])C([H])=C2[H]
[H]N(C(=O)C([H])([H])C([H])([H])[H])C([H])([H])[C@]1([H])C([H])([H])[C@@]1([H])C1=C2C([H])=C(OC2=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N1N=C(C2=C(N=NS2)C([H])([H])[H])\C(=C(/[H])C2=C([H])N(C3=C2C(OC([H])([H])C2=C(F)C(Cl)=C([H])C([H])=C2F)=C([H])C([H])=C3[H])C([H])([H])[H])C1=O
[H]N(\N=C(/[H])C1=C([H])C([H])=NC([H])=C1[H])C1=C2N([H])C([H])=C(C2=NC([H])=N1)C1=C([H])C([H])=C([H])C(OC([H])([H])[H])=C1[H]
[H]N1C2=C(C(=NN2C2=C(C([H])=C([H])C([H])=C2[H])C(F)(F)F)C([H])([H])[H])[C@@]([H])(S[C@]([H])(C1=O)C([H])([H])[H])C1=C([H])C([H])=C(OC2=C([H])C([H])=C([H])C([H])=C2[H])C([H])=C1[H]
[H]O[C@@]([H])(C([H])([H])N1C2=C([H])C([H])=C([H])C(C3=C([H])C(=C([H])C(=C3[H])C(F)(F)F)C(F)(F)F)=C2OC([H])([H])[C@]1([H])C1=C([H])C([H])=C([H])C(OC(F)(F)C([H])(F)F)=C1[H])C(F)(F)F
[H]N(C(=O)C(=C(/[H])C1=C([H])C([H])=C([H])S1)\C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)C([H])([H])[H])C1=NC([H])=C([H])S1
[H]OC(=O)[C@]1([H])N(C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])[H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])[H])C([H])([H])C([H])([H])C1([H])[H]
[H]C1=C([H])C(=C([H])C([H])=C1Br)C1=NN(C(=O)C([H])([H])[H])C([H])([H])C1([H])[H]
[H]OC(=O)C([H])([H])OC1=C([H])C([H])=C(C([H])=C1[H])C1=NC2=C(N1[H])C(=O)N(C(=O)N2C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(N([H])[H])C([H])=C1[H]
[H]N([C@@]1([H])C([H])([H])N2C(=O)N(C3=C([H])C([H])=C(OC(F)(F)F)C([H])=C3[H])C([H])([H])[C@]2([H])C1([H])[H])S(=O)(=O)C1=C([H])C([H])=C([H])C([H])=C1F
[H]N1C(=S)N(C(=O)C1(C1=C([H])C([H])=C(Br)C([H])=C1[H])C1=C([H])C([H])=C(Br)C([H])=C1[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]OC1=C([H])C([H])=C(\C([H])=C2/C(=O)C3=C([H])C([H])=C(OC([H])([H])[H])C([H])=C3C2=O)C([H])=C1O[H]
[H]N(C(=O)C1=C([H])C([H])=C(C(=C1[H])C1=C([H])C2=C([H])N=C([H])C(OC([H])(C([H])([H])[H])C([H])([H])[H])=C2C([H])=C1[H])C([H])([H])[H])C1([H])C([H])([H])C1([H])[H]
[H]ON1C(=O)N([H])C2=C([H])C(Cl)=C([H])C([H])=C2C1=O
[H]OC1=C([H])C([H])=C2C([H])=C([H])C([H])=C(N([H])C(=O)N([H])C3=C([H])C(=C([H])C([H])=C3[H])C([H])([H])O[H])C2=C1[H]
[H]OC(=O)C1=C([H])C([H])=C([H])C([H])=C1N([H])C1=C([H])C(=O)C(=O)C2=C([H])C([H])=C([H])C([H])=C12
[H]N(C(=O)C1=C([H])C([H])=C(Cl)S1)[C@]1([H])C([H])([H])N(C(=O)N(C([H])([H])[H])C([H])([H])[H])C([H])([H])[C@]1([H])N([H])C(=O)C1=C([H])C([H])=C(C([H])=C1[H])N1C([H])=C([H])C([H])=C([H])C1=O
[H]N([H])S(=O)(=O)C1=NN=C(S1)N([H])C(=O)C([H])([H])C([H])([H])[C@@]([H])(C([H])([H])[H])[C@@]1([H])C([H])([H])C([H])([H])[C@@]2([H])[C@]3([H])C(=O)C([H])([H])[C@]4([H])C([H])([H])C(=O)C([H])([H])C([H])([H])[C@]4(C([H])([H])[H])[C@@]3([H])C([H])([H])C(=O)[C@]12C([H])([H])[H]
CCCCN1CCCC[C@H]1[C@H](COC)c1ccccc1
[H]N(C(=O)C(\[H])=C(/[H])C1=C([H])C([H])=C(Br)C([H])=C1[H])C(=S)N([H])C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)N([H])C1=NC([H])=C([H])S1
[H]C([H])=C([H])OC1=C([H])N=C([H])C(=C1[H])N1C([H])([H])C([H])([H])N([H])C([H])([H])C1([H])[H]
[H]N(C1=NC(=C([H])C([H])=N1)C1=C(Cl)N([H])N=C1C([H])(C([H])([H])[H])C([H])([H])[H])C1=NC([H])=C(C([H])=C1[H])N1C([H])([H])C([H])([H])N([H])C([H])([H])C1([H])[H]
[H]N(C(=O)C1=C([H])C(OC([H])([H])C([H])([H])C2=C([H])C([H])=C(Br)C([H])=C2[H])=C(F)C([H])=C1[H])C([H])([H])C1([H])C([H])([H])C([H])([H])N(C2=C([H])C([H])=NC([H])=C2[H])C([H])([H])C1([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])[C@@]([H])(C(=O)N(C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C2(OC([H])([H])C3=C2C([H])=C([H])C([H])=C3[H])C([H])([H])C1([H])[H])C1=C([H])C(F)=C(F)C([H])=C1[H]
[H]N=C(N([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N([H])C(=O)C([H])([H])C1=C(C([H])([H])[H])C([H])([H])C([H])([H])N(N([H])S(=O)(=O)C2=C(C([H])=C([H])C([H])=C2Cl)C([H])([H])[H])C1=O
CC1=C(OC2=C1C=C(C=C2)C1=CC=CC=C1)C(=O)NC1=CN=C(C=C1)N1CCC(COC2=CC=CC(=C2)C(O)=O)CC1
[H]N(C1=C2C(=NC3=C1C([H])=C([H])C(F)=C3[H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])C1=C2C(=NC3=C1C([H])=C([H])C(F)=C3[H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H]
[H]C1=C([H])C(OC([H])([H])[H])=C([H])C2=C1C(=O)C1=C2N=NC(=C1[H])C([H])([H])[H]
[H]N(C(=O)C1=C([H])C(Cl)=C(N([H])C([H])([H])C([H])([H])[H])C([H])=C1OC([H])([H])[H])[C@]1([H])C([H])([H])N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]OC1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[C@]([H])(N([H])[H])C(=O)N1[C@@]([H])(C(=O)N([H])[C@@]([H])(C(=O)N([H])[C@@]([H])(C(=O)N([H])[H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])OC1(C([H])([H])[H])C([H])([H])[H]
[H]OC(=O)C1=C([H])N=C(N([H])C(=O)C2=C([H])C(O[C@@]([H])(C([H])([H])[H])C([H])([H])OC([H])([H])[H])=C([H])C(O[C@@]([H])(C([H])([H])[H])C([H])([H])C3=C([H])C(F)=C([H])C(F)=C3[H])=C2[H])C([H])=C1[H]
[H]N(C1=C([H])C(=C([H])C([H])=N1)C([H])([H])N1C(=O)N(C(=O)C1(C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C(SC(F)(F)F)C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]C1=C([H])C([H])=C(O1)C1=NN(C(=O)C2=C([H])C([H])=C([H])C([H])=C2OC([H])([H])[H])C(SC([H])([H])[H])=N1
[H]OC1=C2C(OC(C([H])([H])[H])(C([H])([H])[H])[C@@]3([H])C([H])([H])C([H])=C(C([H])([H])[H])C([H])([H])[C@@]23[H])=C([H])C(=C1[H])C([H])([H])C([H])([H])C([H])([H])C#CC([H])([H])C([H])([H])C([H])([H])[H]
[H]OC(=O)C([H])([H])C([H])([H])[C@]([H])(N([H])C(=O)C1=C([H])C([H])=C(C([H])=C1[H])[C@]([H])(C([H])([H])C1=C([H])N=C2N=C(N=C(N([H])[H])C2=N1)N([H])[H])C([H])([H])C([H])([H])[H])C(=O)O[H]
[H]N1C(=O)N(C2=C1C([H])=NC1=C([H])C(C3=C(ON=C3C([H])([H])[H])C([H])([H])[H])=C(OC([H])([H])[H])C([H])=C21)[C@@]([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H]
[H]N(C(=O)OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C1=NC2=C([H])C([H])=C(C(=O)N([H])C3=C(C([H])=C(C([H])=C3C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C(Cl)=C2S1
[H]C1=C([H])C([H])=C(C([H])=C1[H])C1(C2=NN=C(O2)C2=NN(C(=C2C([H])([H])[H])C2=C([H])C([H])=C(Cl)C([H])=C2[H])C2=C([H])C([H])=C(Cl)C([H])=C2Cl)C([H])([H])C1([H])[H]
[H]N([H])C([H])([H])C([H])([H])N([H])C1=C([H])C([H])=C(C([H])=N1)C1=NC(=NC([H])=C1[H])N([H])C1=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C(OC([H])([H])[H])=C1[H]
[H]N(C(=O)C1=C(OC([H])([H])[H])C([H])=C(\C([H])=C(/[H])C(=O)N([H])C([H])([H])C(=O)N(C2=C(Cl)C(=C(Cl)C([H])=C2[H])C([H])([H])OC2=C3N=C(C([H])=C(OC([H])([H])C4=C([H])C([H])=C([H])C([H])=N4)C3=C([H])C([H])=C2[H])C([H])([H])[H])C([H])([H])[H])C([H])=C1[H])C([H])([H])[H]
[H]OC1=C([H])C(C([H])=C2[C@@]3([H])C([H])([H])[C@@]4([H])C([H])([H])[C@]2([H])C([H])([H])[C@@]([H])(C3([H])[H])C4([H])[H])=C([H])C2=C1[C@]1([H])C([H])([H])C(=C([H])C([H])([H])[C@@]1([H])C(O2)(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H]
[H]N1C([H])=NC2=C(SC3=C(Cl)C([H])=C([H])C(Cl)=C23)C1=O
[H]N([H])C1=C([H])C([H])=C([H])C([H])=C1N([H])C1=C([H])C2=C(C([H])=C1[H])C(=O)C1=C(C([H])=C([H])N=C1[H])C([H])=C2[H]
[H]OC(=O)C([H])([H])C([H])([H])S[C@@]([H])(C1=C([H])C(OC([H])([H])C2=NC3=C([H])C(Cl)=C([H])C([H])=C3C([H])=C2[H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1C(=O)N(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)OC([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])[C@]([H])(C(=O)OC([H])([H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])C([H])([H])SC([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N=C(N([H])[H])C1=C([H])C(=C([H])C([H])=C1[H])C1=NO[C@@](C(=O)N([H])C2=C(F)C([H])=C(C([H])=C2[H])C2=C([H])C([H])=C([H])C([H])=C2S(=O)(=O)N([H])[H])(C([H])([H])C(=O)OC([H])([H])[H])C1([H])[H]
[H]N=C(N([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N([H])C(=O)C([H])([H])N1C(=O)C(N([H])C([H])(C([H])([H])[H])C([H])([H])[H])=C([H])C([H])=C1C1=C([H])C(N([H])[H])=C([H])C(N([H])[H])=C1[H]
[H]ON(C(=O)C([H])([H])OC1=C([H])C([H])=C(OC([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])=C1[H])C([H])([H])[H]
[H]OC(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])OC1=C(OC([H])([H])[H])C(OC([H])([H])[H])=C([H])C(=C1[H])C([H])([H])C1=C(C(=O)O[C@@]1(O[H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])C1=C([H])C([H])=C2OC([H])([H])OC2=C1[H]
CCCCCCCN(CC1=CC=C(C=C1)N(CC)CC)C(=O)C1=CC=C(C=C1)N(C)C
[H]O[C@]([H])(C([H])([H])N([H])C1([H])C([H])([H])C([H])([H])SC([H])([H])C1([H])[H])[C@@]([H])(N([H])C(=O)C1=C([H])C(=C([H])C(N([H])C([H])([H])C([H])([H])[H])=C1[H])N1C(=O)C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)OC([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])[C@]([H])(C(=O)N1C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C(=O)N([H])[C@]([H])(C(=O)C1=NC([H])=C([H])O1)C([H])(C([H])([H])[H])C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]OC(=O)C1=C([H])C([H])=C(C([H])=C1OC1=NC(OC2=C([H])C(=C([H])C([H])=C2[H])C2=C([H])C([H])=C([H])C(=C2[H])C([H])([H])N([H])[H])=C(F)C([H])=C1F)C([H])([H])[H]
[H]C1=C(Cl)C(Cl)=C([H])C(=C1[H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H]
[H]O[C@@]12C(=O)C(=C([H])[C@@]1([H])[C@@]13O[C@]4(O[C@@]([H])([C@]1([H])C([H])=C(C([H])([H])OC(=O)C([H])([H])C1=C([H])C(OC([H])([H])[H])=C(N([H])[H])C(Br)=C1[H])C2([H])[H])[C@@](O4)(C(=C([H])[H])C([H])([H])[H])C([H])([H])[C@@]3([H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H]
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[H]C1=C([H])C2=C(N=C(N2C2=NC(=NC(=N2)N2C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])N2C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])C([H])(F)F)C(OC([H])(C([H])([H])[H])C([H])([H])[H])=C1[H]
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[H]N(C1=NC(=NC2=C(C(=NN12)C([H])([H])[H])C1=C(N=C(OC([H])([H])[H])C([H])=C1[H])C([H])([H])[H])C([H])([H])[H])[C@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])[H]
[H]N(C1=C(C(=NO1)C([H])([H])[H])C([H])([H])[H])S(=O)(=O)C1=C([H])C([H])=C([H])C([H])=C1C1=C([H])C([H])=C(C([H])=C1C([H])([H])N([H])C([H])([H])C(F)(F)F)C1=NC([H])=C([H])O1
[H]OC1=C([H])C(=C([H])C([H])=C1[H])[C@]1(C(=O)OC([H])([H])C([H])([H])[H])C([H])([H])N(C([H])([H])C2([H])C([H])([H])C2([H])[H])C([H])([H])C([H])([H])C1([H])[H]
[H]N([H])C1=C(C([H])=C([H])[N+]([O-])=C1C1=C([H])C([H])=C([H])C([H])=C1[H])C(=O)C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]ON([H])C(=O)[C@]1([H])N(C([H])([H])C2=C(C([H])=C([H])C([H])=C2[H])C1([H])[H])S(=O)(=O)C1=C([H])C([H])=C(OC([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])=C1[H]
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[H]OC1=C([H])C([H])=C([H])C([H])=C1N1C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])[C@@]([H])(O[H])C2=C(SC(=C2[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]O\C(OC([H])([H])C([H])([H])[H])=C1\C(=NC(=C(C(=O)OC([H])([H])C([H])([H])SC([H])([H])C([H])([H])[H])[C@@]1([H])C([H])([H])[H])C([H])([H])[H])C([H])([H])[H]
[H]N=C(N([H])[H])C1=C([H])C2=C(O[C@]([H])(C3=C([H])C([H])=C([H])C([H])=C3[H])C([H])([H])OC(=O)N([H])C3=C([H])C([H])=C([H])C([H])=C3C([H])([H])N([H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])=C([H])C([H])=C2S1
[H]O[C@@]([H])(C([H])([H])C(=C([H])[H])C(=O)N([H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])N([H])C([H])=N1)C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]OC([H])([H])[C@]([H])(N(C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H])S(=O)(=O)C1=C([H])C([H])=C(OC([H])([H])C([H])([H])[H])C([H])=C1[H])C(=O)N([H])\N=C1/C(=O)N([H])C2=C1C([H])=C([H])C([H])=C2[H]
[H]N1[C@@]2([H])C([H])([H])C([H])([H])[C@]1([H])[C@@]([H])(C(=O)OC([H])([H])[H])[C@@]([H])(C1=C([H])C([H])=C([H])C(\C([H])=C(/[H])Br)=C1[H])C2([H])[H]
[H]OC(=O)C([H])([H])C1([H])C([H])([H])C([H])([H])N(C(=O)C(C([H])([H])[H])(C([H])([H])[H])[C@]([H])(N([H])C(=O)C2=C(F)C([H])=C(C([H])=C2[H])C(=N[H])N2C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]C1=C([H])C(=C([H])C([H])=C1C#N)N1C([H])([H])C([H])([H])N(C(=O)C2=C([H])C(=C([H])C([H])=C2N2C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])[N+]([O-])=O)C([H])([H])C1([H])[H]
[H]N1C(=O)N([H])C(N2C([H])([H])C([H])([H])[C@@]([H])(C3=C([H])C([H])=C([H])C([H])=C3[H])C2([H])[H])=C(C1=O)C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N([H])[C@]([H])(C(=O)N1C([H])([H])SC([H])([H])C1([H])[H])[C@@]1([H])C([H])([H])C([H])([H])[C@]([H])(N([H])C(=O)C2=C([H])C([H])=C([H])C3=C([H])C([H])=C([H])C([H])=C23)C1([H])[H]
[H]OC1=C([H])C([H])=C2C3=C1O[C@@]1([H])C(O[H])=C(C(=O)N([H])C4(C(=O)OC([H])([H])[H])C([H])([H])C4([H])[H])C([H])([H])[C@@]4(O[H])[C@]([H])(N(C([H])([H])C5([H])C([H])([H])C5([H])[H])C([H])([H])C([H])([H])[C@]314)C2([H])[H]
[H]N1C([H])([H])C([H])([H])N(C2=C([H])C3=C(C([H])=C2[H])N2C([H])=C([H])N=C2C2=C(C([H])=C(O2)C2=C([H])C([H])=C(Cl)C([H])=C2[H])C3([H])[H])C([H])([H])C1([H])[H]
[H]N(C(=O)[C@@]1([H])N(C(=O)N(C2=C([H])C(=NC([H])=C2[H])C([H])([H])[H])C1([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C(=C1Cl)C(F)(F)F
CC(C)[C@@H](CO)NC1=NC(NC2=CC=NC=C2)=C2N=CN(C(C)C)C2=N1
[H]N(C(=O)C1=C([H])C([H])=C(C#N)C([H])=C1[H])C1=NC2=C([H])C(=C([H])C([H])=C2N1C([H])([H])C([H])([H])C1=C([H])C([H])=C(Cl)C([H])=C1Cl)N(C(=O)C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])[H]
[H]C1=C([H])C2=C(C([H])=C1[H])C1=C(O[C@]([H])(N2C(=O)C([H])([H])C([H])([H])C([H])([H])[H])C2=C([H])C([H])=C(C([H])=C2[H])C(=O)OC([H])([H])[H])N=C(SC([H])([H])[H])N=N1
[H]C1=C([H])C2=C([H])C([H])=C(OC([H])([H])C([H])([H])C3=C([H])C([H])=C4C([H])=C([H])C([H])=C([H])C4=N3)C([H])=C2C([H])=N1
[H]N([H])S(=O)(=O)C1=NN=C(S1)N([H])S(=O)(=O)C(F)(F)F
[H]N(C(=O)C(\[H])=C(/[H])C1=C([H])C(Cl)=C(Cl)C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=O)C(\[H])=C(/[H])C1=C([H])C(Cl)=C(Cl)C([H])=C1[H]
[H]N(C(=O)C1=C([H])N=C(N=C1C1=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C(OC([H])([H])[H])=C1[H])N([H])C([H])([H])C([H])([H])C1=C([H])C(OC([H])([H])[H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])OC1=C([H])C([H])=C([H])C([H])=C1[H]
[H]O[C@@]([H])(C([H])([H])C([H])([H])[C@@]([H])(C([H])([H])[H])[C@@]([H])(O[H])C([H])([H])C([H])([H])[C@@]([H])(C([H])([H])[H])[C@@]([H])(OC([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N1N=NC(=C1[H])C([H])([H])C([H])([H])C([H])([H])C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[H])C([H])([H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=N[H])N([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])N=C([H])N1[H])C([H])([H])C([H])([H])[C@@]([H])(O[H])[C@@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])[C@@]([H])(O[H])[C@@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])[C@@]([H])(OC([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N1N=NC(=C1[H])C([H])([H])C([H])([H])C([H])([H])C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[H])C([H])([H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=N[H])N([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])N=C([H])N1[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]OC(=O)[C@@]([H])(N([H])C(=O)C([H])([H])C1=C([H])C(N([H])C(=O)[C@@]([H])(N([H])[H])C([H])([H])S[H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])SC([H])([H])[H]
[H]ON([H])C(=O)[C@]([H])(N([H])S(=O)(=O)C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=O)N([H])C1=C([H])C([H])=C([H])C(F)=C1[H]
[H]OC1=C(C([H])=C(C([H])=C1C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1=NO[N+]([O-])=C1C(=O)N([H])[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]OC(=O)C([H])([H])[C@]([H])(N([H])C(=O)[C@@]1([H])C([H])([H])N(C(=O)C([H])([H])C([H])([H])C2([H])C([H])([H])C([H])([H])N([H])C([H])([H])C2([H])[H])C([H])([H])C([H])([H])C1([H])[H])C1=C([H])N=C([H])C(=C1[H])C1=C([H])C2=C(O1)C([H])=C([H])C([H])=C2[H]
[H]OC([H])([H])C(N([H])C1=C2SC(=NC2=NC(SC([H])([H])C2=C([H])C([H])=C([H])C(OC3=C([H])C([H])=C([H])C([H])=C3[H])=C2[H])=N1)N([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]N1C([H])=C(C2=C1N=C(SC([H])([H])[H])N=C2C1=C([H])C([H])=C(C([H])=C1C([H])([H])[H])C([H])([H])[H])C(F)(F)F
[H]N(C(=O)C1=C([H])C(OC([H])([H])C([H])=C(C([H])([H])[H])C([H])([H])[H])=C([H])C(OC2=C([H])C([H])=C(C([H])=C2[H])S(=O)(=O)N2C([H])([H])C([H])([H])[C@]([H])(F)C2([H])[H])=C1[H])C1=NN(C([H])=C1[H])C([H])([H])[H]
[H]N([H])C1=NC(=NN1C(=O)C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H]
[H]N1C(=O)C2=C(N=C1C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])=C(C3=C([H])C([H])=C([H])C([H])=C3[H])C([H])([H])C1([H])[H])C([H])([H])C([H])([H])[C@]([H])(C([H])([H])[H])C2([H])[H]
[H]OC(=O)C1=C([H])C([H])=C([H])C(N([H])C(=O)C2=C(N([H])C(=N2)C([H])([H])[H])C([H])([H])C([H])([H])[C@]23C([H])([H])[C@@]4([H])C([H])([H])[C@]([H])(C([H])([H])[C@]([H])(C4([H])[H])C2([H])[H])C3([H])[H])=C1[H]
[H]C1=C(N(C2=C1C([H])=NC(=N2)C#N)C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N(C1=NC2=C(S1)C([H])=C([H])C([H])=C2[H])C1=C(C#N)C([H])=NC2=C([H])C(OC([H])([H])C([H])([H])C([H])([H])N3C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C3([H])[H])=C(OC([H])([H])[H])C([H])=C12
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[H]N(C(=O)C1=C([H])C([H])=C(Cl)S1)[C@]1([H])C([H])([H])C([H])([H])C([H])([H])[C@]1([H])N([H])C(=O)C1=C([H])C([H])=C(C([H])=C1[H])N1C([H])=C([H])N=C([H])C1=O
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[H]C1=C([H])C([H])=C(S1)[C@](N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])(C(=O)O[C@@]1([H])C([H])([H])[N@+]2(C([H])([H])C([H])([H])C([H])([H])C([H])([H])C3=C([H])C([H])=C([H])C([H])=C3[H])C([H])([H])C([H])([H])[C@@]1([H])C([H])([H])C2([H])[H])C([H])([H])[H]
[H]N(C(=O)C1=C([H])N(C(=C([H])C1=O)C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C1=C([H])C(=C([H])C([H])=C1[H])C(F)(F)F
[H]N1C(=NC(=C1C1=C([H])C([H])=C(F)C([H])=C1[H])C1=C([H])C([H])=NC([H])=C1[H])C1=C([H])C([H])=C(C#N)C([H])=C1[H]
[H]N([H])C(=O)C1=C([H])C(F)=C(F)C([H])=C1OC([H])([H])C1=C([H])C([H])=C(F)C(=C1[H])C(=O)N1C([H])([H])C([H])([H])N([H])C([H])([H])C1([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])OC(=O)[C@@]1([H])C([H])([H])N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[C@@]1([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N1C(OC([H])([H])C2=C([H])C(=C([H])C([H])=C2[H])C(F)(F)F)=NC2=C(C1=O)C(=C([H])C(=O)O2)C([H])([H])C([H])([H])[H]
[H]N1C([H])=C(C2=C1C([H])=C([H])C([H])=C2[H])C1=C([H])C(=C([H])N=C1[H])C1=C([H])SC([H])=C1[H]
[H]OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])N1\C(=N\C(=O)C2=C([H])C([H])=C(S2)C2=C([H])N=C(O2)C([H])([H])[H])N([H])C2=C([H])C(=C([H])C([H])=C12)C([H])([H])N([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC(=O)[C@@]([H])(N1C([H])([H])C([H])([H])C([H])(C([H])([H])N2C([H])([H])C([H])([H])C([H])(OC3=C([H])C(Cl)=C(Cl)C([H])=C3[H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H])C([H])([H])C1=C([H])C(=C([H])C([H])=C1[H])C([H])([H])[H]
[H]N([H])C1=NC2=NN(C([H])=C2C2=NC(=NN12)C1=C([H])C([H])=C([H])O1)C([H])([H])[H]
[H]N([H])C([H])([H])C1=C(N=C(C([H])=C1C1=C(F)C([H])=C(F)C([H])=C1[H])C(=O)N([H])C1=NOC(=C1[H])C([H])([H])[H])C([H])([H])[H]
[H]C1=C(C([H])=C2C([H])=C(OC(F)(F)F)C([H])=C([H])C2=N1)N1C([H])([H])C([H])([H])C([H])(C2=NC(=NO2)C2=C([H])C([H])=C(F)C([H])=C2Cl)C([H])([H])C1([H])[H]
[H]N([H])C1=NC(=C([H])C(=N1)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H])C(=O)N([H])C([H])([H])C1=NC([H])=C([H])C([H])=C1[H]
[H]C1=C([H])C([H])=C([H])C(=N1)C([H])([H])N1C(=O)N(C([H])([H])C([H])([H])C1([H])[H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])[C@@]([H])(C(=N\OC([H])([H])[H])\C([H])([H])N(C(=O)C2=C([H])C(Cl)=C([H])C(Cl)=C2[H])C([H])([H])[H])C2=C([H])C([H])=C(Cl)C(Cl)=C2[H])C([H])([H])C1([H])[H]
[H]N([H])N1C(SC([H])([H])C(=O)N([H])C2=C([H])C([H])=C(C([H])=C2[H])S(=O)(=O)N([H])[H])=NC2=C(C3=C(S2)C([H])([H])[C@]([H])(C([H])([H])[H])C([H])([H])C3([H])[H])C1=O
[H]N(N([H])C(=O)C([H])([H])C1=C(SC2=C1C([H])([H])C([H])([H])C([H])([H])C2([H])[H])N([H])C(=O)C([H])([H])Cl)C([S-])=S
[H]N=C(N([H])C1=C([H])C([H])=C([H])C2=C1C([H])=C([H])C([H])=C2[H])N([H])C1=C(C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C1=NC([H])=C2C(=N1)N(N=C2C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])[C@]1([H])C([H])([H])N([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])[H]
[H]OC1=C([H])C([H])=C(F)C([H])=C1C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[C@](O[H])(C(=O)N([H])C1=C([H])C2=C(C([H])=C1[H])C(=O)OC2([H])[H])C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]O[C@@]1([H])N(C(=O)C([H])([H])C([H])([H])[C@@]1([H])F)C([H])([H])[C@@]([H])(N([H])[H])C([H])([H])C(=O)N1C([H])([H])C2=C(C(=NC(=N2)C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C(F)(F)F)C([H])([H])C1([H])[H]
[H]OC1=C([H])C([H])=C2N([H])C3=C(C2=C1[H])C1=C(C(=C3[H])C2=C([H])C([H])=C([H])C([H])=C2[H])[C@@]([H])(O[H])N([H])C1=O
[H]C1=NC(=NC([H])=C1C([H])([H])C1=C([H])N(C(SC([H])([H])C2=C([H])C([H])=C(F)C([H])=C2[H])=NC1=O)C([H])([H])C(=O)N1C([H])([H])C([H])([H])N(C2=C([H])C([H])=C(Cl)C([H])=C2[H])C([H])([H])C1([H])[H])N(C([H])([H])[H])C([H])([H])[H]
[H]OC(=O)C1=C(O[H])C(=C(OC([H])([H])C([H])([H])C([H])([H])C2=C([H])C([H])=C([H])C(O[H])=C2O[H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]OC1=NC2=C([H])C([H])=C([H])C([H])=C2N1[C@@]1([H])C([H])([H])N(C([H])([H])C([H])([H])[C@]([H])(C2=C([H])C([H])=C(Cl)C(Cl)=C2[H])C([H])([H])N(C(=O)C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])[H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(N1C([H])([H])C([H])([H])N([H])C([H])([H])C1([H])[H])C(=O)C1=C([H])C([H])=C(N([H])C2=NC3=C(C([H])=C(C([H])=C3N=N2)C2=C(C([H])=C([H])C([H])=C2C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C([H])=C1[H]
[H]O[C@@]1([H])C([H])([H])C([H])([H])[C@]2([H])[C@]3([H])C([H])([H])C([H])=C4C([H])([H])[C@@]([H])(O[H])C([H])([H])C([H])([H])[C@]4(C([H])([H])C([H])([H])[H])[C@]3([H])C([H])([H])C([H])([H])[C@]12C([H])([H])[H]
[H]OC([H])([H])C1=C([H])C(=O)N(C([H])=C1C1=C([H])C([H])=C(C([H])=C1[H])[C@]([H])(C([H])([H])[H])[C@@]([H])(C(=O)N1C([H])([H])C([H])([H])[C@]([H])(F)C1([H])[H])[N+]([H])([H])[H])C([H])([H])[H]
[H]O[C@@]1([H])C([H])([H])C([H])([H])[C@@]2(C([H])([H])[H])[C@](O[H])(C1([H])[H])[C@]([H])(O[H])C([H])([H])[C@@]1([H])[C@]3([H])C([H])([H])C([H])([H])[C@]([H])([C@]([H])(C([H])([H])[H])[C@@]4([H])C([H])([H])[C@]4(C([H])([H])[H])[C@@]([H])(C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])[C@@]3(C([H])([H])[H])C([H])([H])[C@@]([H])(O[H])[C@]21O[H]
NS(=O)(=O)C1=CC=C(NC(=O)C(=C\C2=C(Cl)C=CC=C2)\C#N)C=C1
[H]N(C(=O)C([H])([H])[C@@]1([H])C(=O)N(C2=C([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@]2(C(=O)OC([H])([H])[H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1OC([H])([H])[H]
[H]N(C1=NC2=C(C([H])=N1)C([H])=C(N1N2C([H])([H])C([H])([H])C1=O)C1=C(Cl)C([H])=C([H])C([H])=C1Cl)C1=C([H])C([H])=C([H])C([H])=C1OC([H])([H])[H]
[H]OC(=O)C([H])([H])N([H])S(=O)(=O)C1=C([H])C(=C(N([H])C(=O)C2=NC([H])=NC(=C2[H])N(C([H])([H])C2([H])C([H])([H])C2([H])[H])C2([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])=C1[H])C([H])([H])[H]
[H]O[C@@]1([H])C([H])([H])[C@@]2(C([H])([H])[H])[C@@]([H])(C([H])([H])C([H])([H])[C@]2(O[H])C(=O)C([H])([H])SC2=NC([H])=C([H])C([H])=C2[H])[C@]2([H])C([H])([H])C([H])([H])C3=C([H])C4=C(C([H])=NN4C4([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C4([H])[H])C([H])([H])[C@]3(C([H])([H])[H])[C@@]12[H]
[H]N1C([H])=C(C2=C1C([H])=C([H])C(Cl)=C2[H])C1=C([H])C([H])([H])N([H])C([H])([H])C1([H])[H]
[H]O[C@]([H])(C([H])([H])[C@@]([H])(OC([H])([H])[H])C(=O)N([H])[C@]([H])(C(=O)N([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])(C([H])([H])[H])C([H])([H])[H])[C@@]([H])(N([H])C(=O)C1=C([H])C(=C([H])C(=C1[H])C(=O)N([H])[C@@]([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H])N(C([H])([H])[H])S(=O)(=O)C([H])([H])[H])C([H])([H])OC1=C([H])C(F)=C([H])C(F)=C1[H]
[H]N([H])C(=O)C1=C([H])N(N=N1)C([H])([H])C1=C([H])C(Br)=C(Br)C(Br)=C1[H]
[H]N1C(=O)N(C(=O)C11C([H])([H])C([H])([H])N([H])C([H])([H])C1([H])[H])C([H])([H])C1=C([H])C2=C(N=C(N=C2[H])C#N)N1C([H])([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]C1=NC([H])=C(Cl)N=C1[C@@]1([H])C([H])([H])[N@]2C([H])([H])C([H])([H])[C@]1([H])C([H])([H])C2([H])[H]
COC1=C(OC)C=C(OCC2=CC(O[C@@H]3CCN(C)C3)=C(Cl)C=C2)C(Br)=C1
[H]N(C(=O)C1(N([H])C(=O)C2=C([H])C3=C(S2)C([H])=C(C([H])=C3[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])[C@]([H])(C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])SC([H])=C2[H])C([H])([H])C1([H])[H]
[H]OC(=O)C([H])([H])N([H])[C@@]([H])(C(=O)N1C([H])([H])SC([H])([H])[C@@]1([H])C(=O)N([H])C([H])([H])C1=C([H])N=C(C([H])=C1[H])C(=N[H])N([H])[H])C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(C(=O)C([H])([H])[H])C1=C2C(=O)C3=C(N([H])N=C3C2=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])S1
[H]N(C(=O)[C@@]1([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C([H])([H])[C@]1([H])C1=C([H])C([H])=C(Cl)C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=O)[C@@]1([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C([H])([H])[C@]1([H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
CCN(C)CCCN1C(=O)C(C#N)=C(C2=CC=CC=C2)C2=CC=CC=C12
[H]N(C(=O)C1=C([H])C2=C(O1)C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C([H])([H])N1C([H])=NC([H])=C1[H]
[H]N(C1=C([H])C([H])=C([H])C([H])=C1C(=O)N(C([H])([H])C1=C([H])N=C([H])C([H])=C1[H])C([H])([H])C1=C([H])N=C([H])C([H])=C1[H])S(=O)(=O)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H]
[H]OC1=C([H])C([H])=C2N(C3=C(C2=C1[H])C1=C(C(=O)N([H])C1=O)C(=C3[H])C1=C(Cl)C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])SC1=NN=C([H])N1[H]
[H]OC1=C([H])C(O[H])=C(C([H])=C1C1=C(N([H])C(=O)[C@@]2([H])C([H])([H])C([H])([H])[C@]([H])(C([H])([H])N([H])[H])C([H])([H])C2([H])[H])C(=NO1)C(=O)N([H])C([H])([H])C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C1=NC([H])=C([H])C(=N1)N(C1=C(C([H])=C([H])C(OC([H])([H])[H])=C1[H])C([H])([H])[H])C([H])([H])[H])C1=C([H])C(=C([H])C(=C1[H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]C1=C([H])N(C([H])=N1)C1=C([H])C2=C([H])C([H])=C(OC([H])([H])[H])C([H])=C2C([H])=C1[H]
[H]C1=C([H])C2=C(C([H])=C1[H])C1=C(O[C@]([H])(N2C(=O)C([H])([H])C([H])([H])[H])C2=C([H])C([H])=C(SC([H])([H])[H])C([H])=C2[H])N=C(SC([H])([H])C([H])([H])[H])N=N1
[H]OC([H])([H])[C@@]1([H])O[C@@]([H])(N2C([H])=NC3=C2N=C([H])N=C3N([H])C([H])([H])C2=C([H])C([H])=C([H])C(I)=C2[H])[C@]([H])(O[H])[C@]1([H])O[H]
[H]OC1=C([H])C2=C(C([H])=C1[H])C1=C(C3=C([H])C([H])=C(O[H])C([H])=C3O[C@@]1([H])C1=C([H])C([H])=C(OC([H])([H])C([H])([H])N(C([H])(C([H])([H])[H])C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])=C1[H])C([H])([H])C([H])([H])O2
[H]OC(=O)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])N1N(C([H])([H])C([H])([H])[C@]([H])(O[H])C([H])([H])C2=C([H])C([H])=C([H])C(I)=C2[H])C([H])([H])C([H])([H])C1=O
[H]N([H])C1=NC([H])=NC2=C1SC(=C2[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N([H])C1=NC(N([H])[H])=C2N=C(C3=C([H])C([H])=C(Cl)C([H])=C3[H])C([H])([H])C([H])([H])N([H])C2=N1
[H]N(C(=O)C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])(N([H])C(=O)C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H]
[H]O[C@@]([H])(C([H])([H])OC1=C(C([H])=C([H])C([H])=C1C([H])([H])[H])C([H])([H])[H])C([H])([H])N1C([H])([H])C([H])([H])C([H])(C([H])([H])N2C(=O)C3=C([H])C([H])=C([H])C4=C3C(=C([H])C([H])=C4[H])C2=O)C([H])([H])C1([H])[H]
[H]N(C(=O)OC([H])([H])[H])C1=C([H])C([H])=C(OC2=NC([H])=NC3=C2C([H])=C(OC([H])([H])[H])C(OC([H])([H])[H])=C3[H])C([H])=C1[H]
[H]\C(=C(\[H])C1=C([H])C([H])=C(C([H])=C1[H])N(C([H])([H])[H])C([H])([H])[H])C1=C([H])C2=C([H])C(OC([H])([H])[H])=C([H])C([H])=C2O1
[H]OC([H])([H])C([H])([H])N([H])C1=NC2=C(C([H])=C([H])C([H])=C2[H])C(=N1)N([H])C1=C([H])C([H])=C([H])C([H])=C1C([H])([H])[H]
[H]OC(=O)[C@@]([H])(N([H])[H])C([H])([H])C([H])([H])C([H])([H])\N=C(/N([H])[H])N([H])[N+]([O-])=O
CC1=NC2=CC=CC(N3CCN(CCC4=C5OCC6=C(N=CN6C5=CC=C4)C(=O)N4CCC4)CC3)=C2C=C1
[H]N1N([H])C(=C([H])C1=O)C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])N1C(=O)N(C2=C([H])C(OC([H])([H])[H])=NC([H])=N2)C2(C1=O)C([H])([H])C([H])([H])N(C([H])([H])C1=C(C([H])=C([H])C([H])=N1)C([H])([H])[H])C([H])([H])C2([H])[H]
[H]OC1=C(OC([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])=C=C([H])[H])C([H])=C2C(=NC([H])=NC2=C1[H])N([H])C1=C([H])C(Cl)=C(F)C([H])=C1[H]
[H]C1=NN(C2=C1[C@]1(O[C@@]([H])(OC([H])([H])[H])C2([H])[H])C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)N([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C(=O)N([H])[C@]2([H])C([H])([H])C([H])([H])C3=C(C([H])=C([H])C(F)=C3[H])[C@@]2([H])C([H])([H])C2=C([H])C([H])=C([H])N=C2[H])C([H])([H])C1([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C([H])C(F)=C1N([H])C1=C(Cl)C([H])=NC(=N1)N([H])C1=C([H])C2=C(C([H])=C1[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[C@@]([H])(N([H])C(=O)C(F)(F)F)C(=O)N2[H])C([H])([H])[H]
[H]C1=C(SC([H])([H])C(=O)C2=C([H])C([H])=C(OC([H])([H])[H])C(OC([H])([H])[H])=C2[H])N(N=N1)C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]N(C(=O)C1=C([H])C([H])=C2C(=C1[H])C([H])([H])C([H])([H])C([H])([H])[C@@]2([H])N(C(=O)N([H])C1=C([H])C([H])=C(OC(F)(F)F)C([H])=C1[H])[C@@]1([H])C([H])([H])C([H])([H])[C@]([H])(C([H])([H])C1([H])[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C1=NN([H])N=N1
[H]C1=C([H])C([H])=C(C([H])=C1[H])[C@]1([H])C2=C([H])C([H])=C([H])C([H])=C2C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C(=O)C2=C([H])C3=C(OC([H])([H])C([H])([H])O3)C([H])=C2[H])C1([H])[H]
[H]N([H])C(=O)C1=C(C([H])=C([H])C([H])=C1[H])C1=C([H])C(=C([H])C(Cl)=C1[H])N1N=C([H])C2=C([H])N=C(N([H])[C@]([H])(C3=C([H])C([H])=C([H])C([H])=C3[H])C([H])([H])[H])C([H])=C12
[H]N(C(=O)[C@@]1([H])N(C(=O)[C@@]([H])(N([H])C(=O)C2=C(Cl)C([H])=C(Cl)C([H])=C2[H])C([H])([H])C2=C([H])N=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1Cl
[H]OC([H])([H])C([H])([H])C([H])([H])N([H])C1=NC(N2C([H])([H])C([H])([H])N(C(=O)C3=C([H])C([H])=C(C([H])=C3[H])C3=C([H])C([H])=C([H])C([H])=C3[H])C([H])([H])C2([H])[H])=C2C([H])=C(SC2=N1)C([H])([H])C([H])([H])[H]
[H]N=C(N([H])[H])N([H])C1=C([H])C([H])=C(C([H])=C1[H])C(=O)N([H])[C@]([H])(C(=O)N([H])C([H])([H])C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[H])C([H])([H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=N[H])N([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N1C([H])([H])C([H])([H])N(C2=C([H])C(=O)N(C(=N2)C([H])([H])OC2=C([H])C([H])=C([H])C(Cl)=C2[H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N([H])C1=NN2C([H])=C(N=C([H])C2=N1)C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC(=O)[C@]([H])(C1=C([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C([H])([H])C([H])([H])C(\[H])=C(\C1=C([H])N=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N=C(N([H])[H])C1=C([H])C(=C([H])C([H])=C1[H])N1N=C(C([H])=C1C([H])([H])N(C1=C([H])C([H])=C(OC2([H])C([H])([H])C([H])([H])N(C(=N[H])C([H])([H])[H])C([H])([H])C2([H])[H])C([H])=C1[H])S(=O)(=O)C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])C(=C([H])C([H])=C1N1N=NN=C1SC([H])([H])C1=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C(OC([H])([H])[H])=C1[H])C([H])([H])[H]
[H]N(C(=O)C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C1=NC(SC([H])([H])[H])=NC2=NC(=NN12)C1=C([H])C([H])=C([H])O1
[H]N(C(=O)C([H])([H])OC1=C(OC([H])([H])[H])C([H])=C(C([H])=C1Br)C([H])([H])N([H])C1=C([H])C2=C(N([H])C(=O)N2[H])C([H])=C1[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]OC([H])([H])[C@@]([H])(O[H])[C@@]([H])(O[H])[C@]([H])(O[H])[C@]([H])(O[H])[C@@]([H])(N([H])C(=O)[C@]([H])(N([H])C(=O)[C@@]([H])(OC(=O)N(C([H])([H])[H])C([H])([H])C([H])([H])N(C(=O)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])N([H])C([H])=N1)C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]OC([H])([H])[C@@]1(OC(=O)\C(=C(\[H])C2=C([H])C(Cl)=C(F)C([H])=C2[H])C1([H])[H])C([H])([H])OC(=O)C([H])(C([H])([H])[H])C([H])([H])[H]
[H]OC1=NC(=NC2=C1N([H])C([H])=C2C([H])([H])C1=C([H])C([H])=NC([H])=C1[H])N([H])[H]
[H]O[C@@]1([H])[C@@]([H])(O[C@]([H])(C(=O)N([H])C([H])([H])C([H])([H])[H])[C@@]1([H])O[H])N1C([H])=NC2=C1N=C([H])N=C2N([H])C(=O)N([H])C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)N1C([H])([H])C([H])=C([H])C1([H])[H]
[H]N(C(=O)[C@]([H])(C1=C([H])N(C2=C([H])C(=C([H])C([H])=C12)C(=O)N(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])[H])C1=C([H])C([H])=C2OC([H])([H])OC2=C1[H])S(=O)(=O)C1=C([H])C([H])=C(C([H])=C1[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N([H])C1=C([H])C([H])=C([H])C([H])=C1N([H])C(=O)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N([H])C1=C([H])C([H])=NC(=N1)C1=C([H])C([H])=C([H])N=C1[H]
[H]N(C(=O)C([H])([H])[H])C1=NC(=C(S1)C1=C([H])C([H])=NC([H])=C1[H])C1=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C(OC([H])([H])[H])=C1[H]
[H]N1N=C(C(=C1[H])C1=C([H])C(=NC([H])=C1[H])C1=C([H])C([H])=C(OC([H])([H])C([H])([H])C2([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=N1
[H]C1=C([H])C2=C(C([H])=C1[H])N(C(=N2)N1C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C1([H])[H])C([H])([H])C([H])([H])OC([H])([H])C([H])([H])[H]
[H]OC(=O)[C@]([H])(N([H])C(=O)C1=C([H])C([H])=C([H])C([H])=C1N([H])C(=O)C1=C([H])C2=C([H])C([H])=C([H])C([H])=C2N1[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)OC1=C([H])C([H])=C2N(C([H])=C(C2=C1[H])C([H])([H])[H])N(C1=C([H])C([H])=NC([H])=C1F)C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])C(F)=C([H])C2=C1C([H])([H])C([H])([H])[C@]21C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])SC2=NN=C(N2C([H])([H])[H])C2=C(N=C(S2)C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]C1=C(OC([H])([H])[H])C(C2=C3N=C(N=C(N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C#N)N3N=C2C([H])([H])[H])C([H])([H])[H])=C(C([H])=C1OC([H])([H])[H])C([H])([H])[H]
[H]N([H])C1=NC2=C(C([H])=NN2C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H])C2=NN(C(=O)N12)C([H])([H])C1=C([H])C([H])=C([H])C(Cl)=C1[H]
[H]N(OC([H])([H])C1=C(F)C(F)=C(F)C(F)=C1F)C(=O)C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)OC([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC(=O)[C@@]([H])(N([H])C(=O)C1=C(N([H])C(=O)N([H])C2=C(Cl)C([H])=C([H])C([H])=C2Cl)C([H])=C2C([H])=C([H])C([H])=C([H])C2=C1[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N1C2=C(C([H])=C(C([H])=C2[H])[N+]([O-])=O)C2=C1C1=C(N([H])C(=O)C2([H])[H])C([H])=C([H])S1
[H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1C(=O)C2=C([H])C([H])=C([H])C([H])=C2C([H])([H])C1=O
[H]N=C(N([H])C1=NC(=C(S1)C([H])([H])[H])C1=C([H])N([H])C2=C1C([H])=C(Cl)C([H])=C2[H])N([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)[C@]1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C(=O)N1C([H])([H])C([H])([H])N(C2=NC(=C([H])S2)C([H])([H])C([H])([H])[H])C([H])([H])C1([H])[H])C1(C#N)C([H])([H])C1([H])[H]
[H]ON1C2=C3C([H])=C([H])C([H])=C([H])C3=C(N=O)C2=NC2=C([H])C([H])=C([H])C([H])=C12
[H]OC1=C(OC([H])([H])[H])C([H])=C([H])C([H])=C1\C([H])=C(/C#N)C(=O)OC([H])([H])[H]
[H]N(C1=C([H])C([H])=C(C([H])=N1)C(=O)N1C([H])([H])C([H])([H])N(C2=NC([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H])C([H])([H])C1=C(F)C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C([H])C(F)=C1C(=O)OC([H])([H])[H]
[H]N([H])C(=O)C1(C2=C([H])C(F)=C(C([H])=C2[H])C2=C([H])C([H])=C(C([H])=C2[H])[C@]([H])(N([H])[C@]([H])(C(=O)N([H])C2(C#N)C([H])([H])C2([H])[H])C([H])([H])C(F)(C([H])([H])[H])C([H])([H])[H])C([H])(F)F)C([H])([H])C1([H])[H]
[H]N(C(=O)N(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])(C2=C([H])N(C3=C([H])C(=C([H])C([H])=C23)C([H])([H])[H])C2=C([H])C([H])=C(F)C([H])=C2[H])C([H])([H])C1([H])[H]
[H]OC1=C([H])C([H])=C([H])C(=C1[H])[C@]([H])(N1C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C1=C([H])C([H])=C(F)C(Cl)=C1[H])C1=C2C([H])=C(N([H])C([H])([H])C3=C([H])N(N=N3)C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])=C(Br)C2=NC([H])=C1C#N
[H]N(C(=O)N1C([H])([H])C([H])([H])N(C2=NC([H])=C([H])C([H])=C2C([H])([H])[H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C(F)(F)F
[H]OC1=C([H])C([H])=C(C([H])=C1[H])[C@]1([H])N([H])C(=O)C([H])([H])C([H])([H])SSC([H])([H])[C@@]([H])(N([H])C(=O)[C@]([H])(N([H])C(=O)[C@]([H])(N([H])C(=O)[C@]([H])(N([H])C1=O)[C@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])[H])[C@@]([H])(O[H])C([H])([H])[H])C([H])([H])C(=O)N([H])[H])C(=O)N1C([H])([H])C([H])([H])C([H])([H])[C@]1([H])C(=O)N([H])[C@]([H])(C(=O)N([H])C([H])([H])N([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=O)C1=C([H])C2=C(C([H])=C1[H])C(=O)OC21C2=C([H])C([H])=C(O[H])C([H])=C2OC2=C1C([H])=C([H])C(O[H])=C2[H]
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[H]C1=C([H])N=C(C([H])=N1)C1=NN=C(SC([H])([H])C2=C([H])C([H])=C(Br)C([H])=C2[H])S1
[H]N1C([H])([H])C([H])([H])N(C2=C3OC([H])=C([H])OC3=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
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[H]C1=NC([H])=C([H])C(=C1[H])C([H])([H])C([H])([H])C(=O)N(C1=C([H])C([H])=C2N(C3=C(C([H])=C([H])C([H])=C3[H])C2=C1[H])C([H])([H])C([H])([H])[H])C([H])([H])[H]
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[H]OC1=C([H])C(=C([H])C([H])=C1[H])C(=O)C1=C([H])C([H])=C(S1)C1=C([H])C([H])=C(O[H])C(OC([H])([H])[H])=C1[H]
[H]N1C([H])=C([H])C2=C3N(C(=NC3=C([H])N=C12)C([H])([H])[H])C1([H])C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
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[H]\C(=C(/[H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C([H])C([H])=C([H])C([H])=C2OC([H])([H])[H])C([H])([H])C1([H])[H])C([H])([H])N1C(=O)C(=C(C2=C([H])C([H])=C([H])C([H])=C2[H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1=O
[H]N([H])C1=NC2=C(SC3=C([H])C([H])=C([H])C([H])=C23)C(=N1)N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H]
[H]OC1=C2C(=NN(C2=C2C([H])=C(C([H])=C([H])C2=N1)[N+]([O-])=O)C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)N([H])[H])C([H])([H])[H]
[H]N(C(=O)N([H])[C@]1([H])N=C(C2=C([H])C([H])=C([H])C([H])=C2[H])C2=C([H])N=C([H])C([H])=C2N(C1=O)C([H])([H])[H])C1=C([H])C([H])=C([H])C(=C1[H])C([H])([H])[H]
[H]O[C@@]1([H])C2=C(C([H])=C([H])C([H])=C2[H])C([H])([H])[C@]1([H])N([H])C(=O)C1=C([H])N(C(=N1)C1=C([H])C([H])=C([H])C([H])=C1Cl)C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]OC1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[C@]([H])(N([H])[H])C(=O)N(C([H])([H])[H])C([H])([H])C(=O)N([H])[C@]([H])(C(=O)N([H])[C@@]([H])(C(=O)N([H])[H])C([H])([H])C1=C([H])C([H])=C2C([H])=C([H])C([H])=C([H])C2=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)N([H])C1=C(C2=C([H])C(=C([H])C([H])=C2N=C1[H])C([H])([H])[H])C1=C(C([H])=C([H])C([H])=C1[H])C([H])([H])[H])C1=C([H])C([H])=C(F)C([H])=C1F
[H]O[C@]1(C([H])([H])[H])C([H])([H])[C@@]([H])(O[C@]([H])(C([H])([H])SC#N)C1([H])[H])C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]N([H])C(=O)C([H])([H])N1C2=C([H])C([H])=C([H])C([H])=C2C(=N[C@]([H])(N([H])C(=O)[C@@]([H])(C([H])([H])[H])C([H])([H])C2=C([H])C([H])=C(F)C(F)=C2[H])C1=O)C1=C([H])C2=C(OC([H])([H])O2)C([H])=C1[H]
[H]N(C1=C([H])C(Cl)=C(F)C([H])=C1[H])C1=C(C#N)C([H])=NC2=C([H])C([H])=C(N([H])C([H])([H])C3=C([H])C(C#N)=C([H])C([H])=C3[H])C([H])=C12
[H]C1=NC(=NC(=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H])N1C([H])([H])C([H])([H])C2(C(=O)N(C([H])([H])C3=C([H])C(Cl)=C([H])C([H])=C3[H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]N(C([H])([H])C([H])([H])C([H])([H])OC1=C([H])C([H])=C([H])C2=C1C([H])=C([H])N2[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(C(=O)C([H])([H])N1C([H])([H])C([H])([H])N(C2=C([H])C([H])=C(Cl)C([H])=C2[H])C([H])([H])C1([H])[H])[C@@]1([H])[C@@]2([H])C([H])([H])[C@]3([H])C([H])([H])[C@]([H])(C2([H])[H])C([H])([H])[C@@]1([H])C3([H])[H]
[H]OP(=O)(O[H])C(=O)N([H])C([H])([H])C([H])([H])N([H])C(=O)C1=C([H])C([H])=C(OC2=C([H])C([H])=C([H])C([H])=C2[H])C([H])=C1[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])[C@@]1([H])C([H])([H])C([H])([H])C([H])([H])N2C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@]12[H]
[H]OC(=O)[C@@]([H])(N([H])C(=O)[C@@]1([H])N(C(=O)[C@@]([H])(N([H])C([H])([H])C2=C([H])N([H])C([H])=N2)C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C2=C(C([H])=C([H])C([H])=C2[H])C1([H])[H])C([H])([H])C([H])([H])SC([H])([H])[H]
[H]OC(=O)C([H])([H])N(C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])[N+]([O-])=O)S(=O)(=O)C1=C([H])C([H])=C(N([H])C(=O)N([H])S(=O)(=O)C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])=C1[H]
[H]C1=C([H])C(=NC(=C1[H])C([H])([H])C1=C([H])C(Cl)=C([H])C([H])=C1OC([H])([H])C1=C([H])C([H])=C(Cl)C([H])=C1[H])C([O-])=O
[H]OC([H])([H])C([H])([H])SC1=C([H])C(C2=C([H])C([H])=C([H])N2[H])=C2C(=O)N([H])C3=C([H])C([H])=C(F)C1=C23
[H]N(\N=C(\C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])[H])C([H])([H])[H])C(=O)C([H])([H])N([H])C(=O)C(\[H])=C(/[H])C1=C([H])C([H])=C([H])O1
CC(C)C[C@H](CO)NC1=NC(SCC2=CC=C(C=C2)C#N)=NC2=C1SC(N)=N2
[H]O[C@@]1([H])OC(=O)C([H])([H])[C@]1([H])N([H])C(=O)[C@@]([H])(N([H])C(=O)C([H])([H])C([H])([H])SC1=C([H])C([H])=C([H])C2=C1C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])[C@]1([H])C2=C(C([H])=C([H])C([H])=C2[H])C([H])([H])N(C(=O)O[C@@]2([H])C([H])([H])[N@]3C([H])([H])C([H])([H])[C@]2([H])C([H])([H])C3([H])[H])C1([H])[H]
[H]N(C(=O)N([H])C1([H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC(N2C([H])([H])[C@@]3([H])O[C@]([H])(C([H])([H])C3([H])[H])C2([H])[H])=C2C([H])=NN(C2=N1)C1([H])C([H])([H])C([H])([H])N(C(=O)OC([H])([H])[H])C([H])([H])C1([H])[H]
OP(O)(=O)C(NC1=CC(CC2=CC=CC=C2)=CN=C1)P(O)(O)=O
[H]N(C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1=C(N([H])C2=C([H])C([H])=C(C([H])=C12)C([H])([H])[H])C1=C([H])C([H])=C(Br)C([H])=C1[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]OC([H])([H])C([H])([H])C([H])([H])C([H])([H])OC1=C([H])C([H])=C([H])C([H])=C1N([H])C(=O)N([H])[C@@]1([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C3C([H])=C(F)C([H])=C([H])C3=C2[H])C([H])([H])C1([H])[H]
[H]OC1=C([H])C([H])=C2N([H])C3=C(C2=C1[H])C1=C(C(=O)N([H])C1=O)C(=C3[H])C1=C([H])C(Cl)=C([H])C([H])=C1[H]
[H]N(C(=O)C1=C(F)C([H])=C([H])C([H])=C1[H])C1=C([H])C(=NN1C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N1C2=C([H])C([H])=C(Cl)C([H])=C2C(=C1C([H])(C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])([H])N([H])C([H])([H])C1([H])[H]
[H]N(\N=C1/C(=O)N(C2=C([H])C(OC([H])([H])[H])=C([H])C([H])=C12)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C(=O)C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]O[C@]([H])(C([H])([H])N([H])C([H])([H])C1=C([H])C(=C([H])C([H])=C1[H])C([H])([H])C([H])([H])[H])[C@@]([H])(N([H])C(=O)[C@]([H])(N([H])C(=O)S[C@]1([H])C([H])([H])OC([H])([H])C1([H])[H])C([H])([H])S(=O)(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C1=C([H])C(F)=C([H])C(F)=C1[H]
[H]C1=C(C2=NSN=C2SC([H])([H])C([H])([H])[H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H]
[H]OC1=NC2=C([H])C3=C([H])C(OC([H])([H])C([H])([H])C([H])([H])O[H])=C([H])C([H])=C3N([H])C2=N1
[H]C1=C([H])C(=C([H])C([H])=C1Cl)C1=C(C(=NN1C1=C([H])C([H])=C(Cl)C([H])=C1Cl)C1=NN=C(O1)[C@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])[H])C([H])([H])[H]
[H]O[C@@]([H])(C([H])([H])N1C2=C([H])C([H])=C([H])C([H])=C2C2=C([H])C([H])=C([H])C([H])=C12)C([H])([H])N1C([H])([H])C([H])([H])N(C(=O)C2=C([H])C([H])=C([H])O2)C([H])([H])C1([H])[H]
[H]OC(=O)C1=C(O[H])C(=C([H])C([H])=C1[H])C(=O)C(\[H])=C(/[H])C1=C([H])C([H])=C([H])C(OC([H])([H])C2=NC3=C([H])C([H])=C([H])C([H])=C3C([H])=C2[H])=C1[H]
[H]OC(C#CC1=C([H])C([H])=C2N=C([H])N=C(N([H])C3=C([H])C(Cl)=C(F)C([H])=C3[H])C2=C1[H])(C([H])([H])[H])C([H])([H])[H]
[H]OC1=C(Cl)C([H])=C2C(=C1[H])[C@@]1([H])C3=C(C(=C([H])C([H])=C3[H])N3C(=O)C([H])([H])C([H])([H])C3([H])[H])C([H])([H])C([H])([H])[C@]1([H])N(C([H])([H])[H])C([H])([H])C2([H])[H]
[H]N([H])S(=O)(=O)C([H])([H])C([H])([H])\N=C(/[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C([H])=C(C([H])([H])[H])C([H])([H])N1C(=O)C(=O)C2=C1C([H])=C([H])C(Br)=C2[H]
COC(=O)C1=CC2=C(NCC1)N=CN=C2NC1=CC(Cl)=C(OC2=CC=CC(=C2)C(F)(F)F)C=C1
[H]N([H])C1=C2C(=NC([H])=N1)N(N=C2C1=C([H])C2=C([H])C([H])=C(OC([H])([H])C([H])([H])[H])C([H])=C2C([H])=C1[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C1=C2C([H])=C(C([H])=C([H])C2=NC([H])=N1)C1=C([H])C([H])=C(O1)C([H])([H])N([H])C([H])([H])C([H])([H])S(=O)(=O)C1=NC([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C(OC([H])([H])C2=C([H])C(F)=C([H])C([H])=C2[H])C(=C1[H])C(F)(F)F
[H]N(C(=O)[C@@]([H])(N([H])[C@@]([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C(F)(F)F)C([H])([H])S(=O)(=O)C1=NC([H])=C([H])S1)C1(C#N)C([H])([H])C1([H])[H]
[H]ON([H])C(=O)C([H])([H])C([H])([H])N([H])C(=O)C1=C([H])C([H])=C(OC([H])([H])C2=C([H])C(=NC3=C([H])C([H])=C([H])C([H])=C23)C([H])([H])[H])C([H])=C1[H]
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[H]C([H])=C([H])C([H])([H])N1C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])[C@@]([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C(=O)N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H]
[H]OC(=O)C([H])([H])C([H])([H])N([H])C(=O)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1N=C(C([H])=C1C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C(OC(F)(F)F)C([H])=C1[H]
[H]N([H])C(=O)C1=C2C(OC([H])([H])[C@@]([H])(N(C([H])([H])C([H])([H])C([H])([H])C3=C([H])N([H])C4=C3C([H])=C(C#N)C([H])=C4[H])C3([H])C([H])([H])C([H])([H])C3([H])[H])C2([H])[H])=C(F)C([H])=C1[H]
[H]N([H])C1=C(C([H])=C([H])C([H])=C1[H])C(=O)N1C([H])([H])C([H])([H])C([H])(N2C([H])([H])C([H])([H])C([H])(C([H])([H])C2([H])[H])C2(OC([H])([H])C([H])([H])O2)C2=C([H])C([H])=C(C([H])=C2[H])S(=O)(=O)C2=C([H])C([H])=C(OC([H])([H])[H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N1C([H])([H])[C@@]([H])(N2C([H])([H])C([H])([H])N(C3=NC4=C(O3)C([H])=C([H])N=C4[H])C([H])([H])C2([H])[H])C([H])([H])[C@@]1([H])C(=O)N1C([H])([H])C([H])([H])C(F)(F)C1([H])[H]
[H]C1=C([H])C(=C([H])C(OC([H])([H])[H])=C1[H])C([H])([H])C1=C([H])C2=C(OC([H])([H])[H])C([H])=C(C([H])=C2OC1=O)C([H])([H])Br
CCNC(=O)C1=CC(NS(=O)(=O)C2=CC=C(Br)C=C2OC(F)(F)F)=CC=C1OC1=CC(Cl)=CN=C1
[H]N(C([H])([H])C([H])([H])C([H])([H])SC1=NN=C(N1C([H])([H])[H])C1=C(N=C([H])O1)C([H])([H])[H])[C@@]1([H])C([H])([H])C([H])([H])[C@]2(C3=C([H])C([H])=C(C([H])=C3[H])C(F)(F)F)C([H])([H])[C@]12[H]
Cl[H].CCCCCCNC1=C2CCCCC2=NC2=CC=C(OC)C=C12
CC1(C)CCC2=C(N=C3SC4=C(N=CN=C4NCCN4CCOCC4)C3=C12)N1CCOCC1
[H]OC(=O)C([H])([H])[C@@]1([H])N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]2([H])N(C1=O)C([H])([H])C([H])([H])C2([H])[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C1([H])C([H])([H])C1([H])[H])C([H])([H])C1=C(Br)N([H])C2=C1C([H])=C([H])C([H])=C2[H]
[H]C([H])=C(C1=C([H])C2=C(C([H])=C1[H])[C@]([H])(N([H])C(=O)C([H])([H])[C@@]([H])(N([H])S(=O)(=O)C1=C([H])C(=C([H])C([H])=C1[H])C(F)(F)F)C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])N([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
O=C1CN(CCC2CCOCC2)C2=NC(=CN=C2N1)C1=CC=C(C=C1)C1=NNC=N1
[H]N1C([H])=C(C2=C1C([H])=C([H])C([H])=C2[H])C1=C([H])C([H])([H])N(C([H])([H])[C@]2([H])OC3=C([H])C([H])=C([H])C([H])=C3N([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]N1C(=NC2=C([H])C([H])=C(SC([H])([H])[H])C([H])=C12)C1=C([H])C([H])=C(C([H])=C1[H])C1=C(F)C([H])=C([H])C([H])=C1[H]
[H]N1N=C(OC([H])([H])C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C([H])C(=C2Cl)C(F)(F)F)C([H])([H])C([H])(C2=C([H])C([H])=C([H])C([H])=C2[H])C2=C([H])C([H])=C([H])C([H])=C2[H])C2=C([H])C([H])=C([H])C([H])=C12
[H]C1=C(I)C([H])=C(C(=C1[H])C1=C(OC([H])([H])[H])C([H])=C(F)C(=C1[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])N1C(=O)O[C@]([H])(C2=C([H])C(=C([H])C(=C2[H])C(F)(F)F)C(F)(F)F)[C@]1([H])C([H])([H])[H]
[H]OC1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1C([H])([H])C([H])([H])[C@@]([H])(N([H])C(=O)C([H])([H])N([H])C(=O)C2=C([H])C(=C([H])C([H])=C2[H])C(F)(F)F)C1([H])[H]
[H]C([H])([H])N1C([H])([H])C([H])([H])[C@]2(O[C@@]([H])(OC2([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]C1=NC(=C([H])C([H])=C1[H])C1=NN=C(SC([H])([H])C2=C([H])C(=C(Cl)C([H])=C2[H])C(F)(F)F)N1C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC(=O)[C@@]([H])(N([H])[H])C([H])([H])C([H])([H])SC([H])([H])[C@@]1([H])O[C@@]([H])(N2C([H])=NC3=C2N=C(N=C3N([H])[H])C([H])([H])[H])[C@]([H])(O[H])[C@]1([H])O[H]
[H]N([H])C1=NC(=C([H])C(C2=C([H])C([H])=C(O2)C([H])([H])[H])=C1C#N)C1=C([H])C([H])=C([H])O1
[H]C1=C([H])C([H])=[N+](C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])OC([H])([H])[C@@]1([H])O[C@@]([H])(OC1([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C(O1)C#N)C1=C([H])C(=C([H])C([H])=C1N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])N([H])S(=O)(=O)C([H])([H])[H]
[H]C1=C(SC2=C1N=C([H])N(C2=O)[C@]1([H])C([H])([H])N(C(=O)N(C([H])([H])[H])[C@]2([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C2OC([H])([H])C([H])([H])OC2=C1[H]
[H]N1C([H])([H])C2=C([H])C(=C([H])C([H])=C2C([H])([H])[C@]1([H])C([H])([H])[H])[N+]([O-])=O
[H]C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])[C@]2([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@@]2([H])C1([H])[H]
[H]N([H])C1=C([H])C(=NC2=C([H])C([H])=C(N([H])C(=O)C(\[H])=C(/[H])C3=C([H])C(Cl)=C([H])C([H])=C3[H])C([H])=C12)C([H])([H])C([H])([H])C([H])([H])[H]
[H]N([H])C1=NC([H])=C([H])N2C(=NC(=C12)C1=C([H])C([H])=C(OC2=C([H])C([H])=C([H])C([H])=C2[H])C([H])=C1[H])[C@@]1([H])C([H])([H])C([H])([H])[C@]([H])(C(=O)N([H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N1C([H])=C(C2=C([H])C(F)=C([H])C([H])=C12)C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C(OC([H])([H])[H])(C([H])([H])[S@+]([O-])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N(C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C1([H])C([H])([H])C([H])([H])N(C(=O)C2=C([H])C3=C([H])C([H])=C([H])C([H])=C3C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N(C1=C([H])C([H])=C(I)C([H])=C1F)C1=C(C(=O)N(C2=C1C(=O)N([H])C([H])=N2)C([H])([H])[H])C([H])([H])[H]
[H]N1C(=O)C2=NN(C(=O)N2C2=C1C([H])=C([H])C([H])=C2[H])C1=C([H])C([H])=C(OC(=O)C([H])([H])[H])C([H])=C1[H]
[H]OC1=C(Br)C([H])=C(C([H])=C1Br)C([H])([H])N1C2=C(N=C1C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])=C([H])C([H])=C2[H]
[H]O[C@]1([H])C([H])([H])C2=C([H])C([H])([H])[C@@]3([H])[C@]4([H])C([H])([H])C([H])([H])[C@]([H])([C@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])C(=O)C([H])(C([H])([H])[H])C([H])([H])[H])[C@@]4(C([H])([H])[H])C([H])([H])C([H])([H])[C@]3([H])[C@@]2(C([H])([H])[H])C([H])([H])C1([H])[H]
[H]C1=C(N(C([H])([H])[H])S(=O)(=O)C([H])([H])[H])C(OC([H])([H])C([H])([H])C([H])([H])[H])=C([H])C(=C1[H])[N+]([O-])=O
[H]N(C(=O)C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C1=C(OC([H])([H])[H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)[C@@]([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N([H])C1=NC(=C([H])C(=N1)N([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])N1C([H])([H])C([H])([H])[C@@]([H])(N([H])C([H])([H])[H])C1([H])[H]
[H]N(C1=NC(=C([H])C([H])=N1)C1=C([H])C([H])=C(C([H])=C1[H])C(=O)N([H])C([H])([H])C#N)C1=C([H])C([H])=C(OC([H])([H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H])C([H])=C1[H]
[H]SC[C@H](N)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC1=CNC2=C1C=CC=C2)C(=O)N[C@@H](CCCNC(N)=N)C(=O)NCC(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CC1=CN=CN1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](CS[H])C(O)=O
[H]OC(=O)C1=C([H])C2=C([H])C([H])=C(C([H])=C2C([H])=C1[H])C(=C(F)F)C1=C([H])C2=C(C([H])=C1[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C([H])([H])C2(C([H])([H])[H])C([H])([H])[H]
[H]N(C1=NC2=C(Cl)C([H])=C([H])C([H])=C2C([H])=C1[H])[C@@]1([H])C([H])([H])C([H])([H])C([H])([H])[C@]([H])(N([H])C([H])([H])C2=C([H])SC([H])=C2[H])C1([H])[H]
[H]N(C(=O)C(\[H])=C(/[H])C1=C([H])C2=C([H])C([H])=C([H])C([H])=C2C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C(OC([H])([H])[H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N(C(=O)C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C1=NC(=C(S1)C1=NN(N=N1)C([H])([H])C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C1=C([H])C(=C([H])C(=C1[H])C([H])([H])[H])C([H])([H])OC1=C([H])C([H])=C(C([H])=C1[H])C1=NN(N=N1)C([H])([H])C([H])([H])C#N
[H]N(C(=O)C1=C([H])C([H])=C([H])C(=C1C1=C([H])C([H])=C(C([H])=C1[H])C(F)(F)F)C([H])([H])[H])C1=C([H])C2=C(C([H])=C1[H])C([H])([H])[C@]([H])(N([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C2([H])[H]
[H]OC([H])([H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])C1(C(=O)N([H])C(=O)N([H])C1=O)C1=C([H])C([H])=C(OC2=C([H])C([H])=C([H])C([H])=C2[H])C([H])=C1[H]
[H]N1C([H])=NC([H])=C1C([H])([H])N(C1=C([H])C([H])=C([H])C(OC2=C([H])C([H])=C(Cl)C([H])=C2[H])=C1[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C1=NC2=C(C(=NN2C2=C(Cl)C([H])=C(Cl)C([H])=C2Cl)C([H])([H])C([H])([H])[H])C(=O)N1[H]
[H]N1N=C(C2=C([H])C(=C([H])C([H])=C12)N1C([H])([H])C([H])([H])[C@@]([H])(N(C([H])([H])[H])C([H])([H])[H])C1([H])[H])S(=O)(=O)C1=C2C([H])=C([H])C([H])=C([H])C2=C([H])C([H])=C1[H]
[H]N1C([H])([H])C([H])([H])C([H])(N(C(=O)C([H])([H])OC2=C([H])C(=C([H])C(=C2[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])C2=C([H])C(Cl)=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N([H])C([H])([H])C1=C(C2=C([H])C([H])=C(C([H])=C2[H])C([H])([H])[H])C2=C([H])C(=C([H])C([H])=C2N=C1C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C1=NN([H])N=N1
[H]C1=C([H])C(F)=C(C([H])=C1[H])[C@]1([H])OC2=C(N=NC(SC([H])([H])C([H])([H])C([H])([H])[H])=N2)C2=C(C([H])=C([H])C([H])=C2[H])N1C(=O)C([H])([H])C([H])([H])[H]
[H]OC(=O)C1=C([H])C([H])=C([H])C2=C1N(C1=C(S2)C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C([H])C(=O)N(C(=O)N2C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C1([H])[H]
[H]OC1=C([H])C([H])=C([H])C(\C([H])=N\N([H])C(=O)C2=C(N(N=N2)C2=NON=C2N([H])[H])C([H])([H])N(C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])[H])=C1[H]
CC(C)C[C@H](NC(=O)NC1=C(Cl)C=CC=C1)C(=O)NO
[H]C1=C([H])C([H])=C2C(=C1[H])C(=O)C(=O)C([H])=C2C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]OC1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[C@]([H])(N([H])[H])C(=O)N([H])[C@@]1([H])C2=C(C([H])=C([H])C([H])=C2[H])C([H])([H])[C@@]1([H])C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C1=C([H])C([H])=C(OC2=C([H])C([H])=C([H])C([H])=C2[H])C([H])=C1[H])C1=C(C#N)C([H])=NN2C([H])=C([H])C(=C12)C([H])([H])[H]
[H]N(C(=O)C1=C2N(C(=N1)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C1=C([H])C([H])=C([H])C([H])=N1
[H]OC(=O)C([H])([H])C1=C([H])\C(=C(\[H])C2=C([H])C([H])=C(SC([H])([H])[H])C([H])=C2[H])C2=C([H])C([H])=C(F)C([H])=C12
[H]OC(=O)C([H])([H])N(C(=O)[C@]([H])(C([H])([H])[H])C([H])([H])S[H])C([H])(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H]
[H]C1=C([H])N(C([H])=N1)C([H])([H])C1=C([H])C(=O)OC2=C([H])C(OC3=C([H])C([H])=C([H])C(F)=C3[H])=C([H])C([H])=C12
[H]N(C(=O)C1=C([H])C([H])=C(C(Cl)=C1[H])C1=C([H])N=C([H])C([H])=C1[H])C1=NC(=C([H])C([H])=C1[H])C([H])([H])[H]
[H]OC(=O)C([H])([H])[C@]([H])(N([H])[H])C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])C([H])([H])C([H])([H])C(=O)N([H])[C@]([H])(C([H])([H])N([H])[C@]([H])(C(=O)N([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])O[H]
[H]N([C@@]([H])(C1=NC2=C(N1[H])C([H])=C([H])C(=C2[H])C(=O)OC([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])[C@]1([H])C([H])([H])C(=O)N([H])S1(=O)=O)S(=O)(=O)C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C1=C2C(=NC3=C2C([H])([H])C([H])([H])C([H])([H])C3([H])[H])N=C([H])N1[H])C1=C([H])C(Br)=C([H])C([H])=C1[H]
[H]N(C(=O)N1C([H])([H])C([H])([H])N(C2=C([H])C([H])=C([H])C([H])=C2C(F)(F)F)C([H])([H])C1([H])[H])C1=C([H])C([H])=C([H])C2=NC([H])=C([H])C([H])=C12
[H]OC(=O)C([H])([H])[C@]([H])(N([H])C(=O)[C@@]([H])(C([H])([H])C(=O)N([H])C([H])([H])C([H])([H])C(=O)C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])=O
[H]N1C(=O)C([H])=C(C2=C1C([H])=C([H])C(=C2[H])N(C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C(F)(F)F
[H]C1=C([H])C(N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H])=C2C([H])=C([H])C(=NC2=C1OC([H])([H])[H])C1=C(OC([H])([H])[H])C([H])=C(C([H])=C1OC([H])([H])[H])C([H])([H])OC([H])([H])[H]
[H]N([H])[C@@]1([H])C([H])([H])C([H])([H])[C@]([H])(N([H])C2=NC3=C(N=C([H])N3C([H])(C([H])([H])[H])C([H])([H])[H])C(=N2)N([H])C([H])([H])C2=C([H])C([H])=C(S2)C2=C([H])C(=C([H])C([H])=C2[H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]OC([H])([H])C([H])([H])[C@@]1([H])N(C2=NC3=C(N([H])C([H])([H])N3C([H])(C([H])([H])[H])C([H])([H])[H])C(=N2)N([H])C([H])([H])C([H])([H])N([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(C(=O)C#CC([H])([H])C([H])([H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C1=NC([H])=C2N=C([H])N=C(N([H])C3=C([H])C(Cl)=C(F)C([H])=C3[H])C2=C1[H]
[H]N1N=C(C2=C([H])C([H])=C(OC([H])([H])[H])C3=NC(=C([H])N23)C(F)(F)F)[C@]([H])(C([H])([H])[H])C([H])([H])C1=O
[H]OC(=O)[C@]([H])(N([H])C(=O)C1=C([H])C([H])=C(C([H])=C1[H])N(C([H])([H])[H])C([H])([H])C1=NC2=C(N=C(N=C2N=C1[H])N([H])[H])N([H])[H])C([H])([H])C([H])([H])C(=O)N([H])C1=C([H])C([H])=C(O[H])C(O[H])=C1[H]
[H]OC1=C(O[H])C([H])=C2C(=C1[H])C([H])([H])C([H])([H])N([H])[C@]2([H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C(N([H])S(=O)(=O)C2=C([H])C([H])=C(N([H])C(=O)N([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])=C2[H])=C([H])C([H])=C1[H]
[H]C1=C([H])C(Cl)=C([H])C(=C1[H])N1C(=O)N(C([H])([H])C([H])([H])N2C([H])([H])C([H])([H])C([H])([H])[C@]([H])(C3=C([H])C([H])=C([H])C(OC([H])([H])[H])=C3[H])C2([H])[H])C([H])([H])C1([H])[H]
[H]N(C(=O)C([H])([H])C1=C(N(C(=O)C2=C([H])C([H])=C(Cl)C([H])=C2[H])C2=C1C([H])=C(OC([H])([H])[H])C([H])=C2[H])C([H])([H])[H])C1=C([H])C([H])=C(SC([H])([H])[H])C([H])=C1[H]
[H]N(C(=O)C([H])([H])N1C([H])([H])C([H])([H])C([H])(N(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H])[C@]1(C(=O)N([H])C2=C([H])C(Cl)=C([H])C(Cl)=C12)C1=C([H])C(Cl)=C(Cl)C([H])=C1[H]
[H]N(C1=NN([H])C(=C1[H])C([H])([H])[H])C1=C(Cl)C([H])=NC(O[C@]([H])(C2=NC([H])=C(F)C([H])=N2)C([H])([H])[H])=N1
[H]\C(=C(/[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C(=N\OC([H])([H])[H])\C1=NC2=C(O1)C([H])=C([H])C([H])=N2
[H]N1N=C([H])C(=C1[H])C1=C([H])C([H])=C([H])C2=C1C([H])([H])C([H])([H])[C@@]2([H])C1=NC([H])=C([H])N1[H]
[H]N=C(N([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N([H])C(=O)C([H])([H])N1C(=O)C(=NC(Cl)=C1C1=C([H])C([H])=C([H])C(N([H])[H])=C1[H])N([H])C([H])([H])[H]
[H]N=C(N([H])[H])C1=C([H])C([H])=C(N([H])C(=O)N([H])C([H])([H])C(=O)N([H])C([H])([H])C2=C([H])C([H])=C(Cl)C(Cl)=C2[H])C([H])=C1[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])OC(=O)[C@]1([H])N(C(=O)C(=O)C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C1([H])[H]
[H]O[C@@]([H])(C([H])([H])C([O-])=O)C([H])([H])[C@]([H])(O[H])C([H])([H])C([H])([H])N1C(=C(C(=C1C([H])(C([H])([H])[H])C([H])([H])[H])S(=O)(=O)N(C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]N(C(=O)C([H])([H])SC1=NC2=C(C(=O)N1C1=C([H])C([H])=C([H])C([H])=C1OC([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C1=C([H])C([H])=C2N=C([H])C([H])=NC2=C1[H]
FC(F)(F)C1=CC(CC(=O)N2CCC3(CC2)CCN(CNC(=O)C2=CC=CC=C2)C2=C(O3)C=CC=C2)=CC=C1
[H]OC(=O)C1=NN2C(=C1[H])C1=C([H])C([H])=C(Cl)C([H])=C1N=C2O[H]
[H]OC1=C(Br)C([H])=C(C([H])=C1Br)C1=C([H])C([H])=C(C([H])=C1[H])C1=C(OC(=N1)C1=C([H])C([H])=C(C([H])=C1[H])C(F)(F)F)C([H])([H])[H]
[H]N([H])C([H])([H])C([H])([H])C([H])([H])[C@@]([H])(N1C(=O)C2=C([H])C([H])=C([H])C(N3C([H])([H])C([H])([H])N(C([H])([H])C3([H])[H])[C@@]([H])(C3=C([H])C([H])=C([H])C([H])=C3[H])C([H])([H])[H])=C2C1=O)C1=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]C1=NC2=C(C([H])=C([H])C(=C2[H])C(=O)N2C([H])([H])C([H])([H])C([H])([H])[C@@]3([H])C4=C([H])C([H])=C(C([H])=C4C([H])([H])C([H])([H])[C@]23[H])C(=O)C([H])([H])C([H])([H])[H])C1([H])[H]
[H]O[C@@]([H])(C([H])([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])[C@@]([H])(N([H])C(=O)C1=C([H])C(=C([H])C(=C1[H])N(C([H])([H])[H])S(=O)(=O)C([H])([H])[H])C(=O)N([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]OC(=O)C([H])([H])[C@]([H])(N([H])C(=O)[C@@](N([H])C(=O)OC([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])(C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])C(=O)C([H])([H])F
[H]C1=C([H])C(=C([H])C(=C1[H])C1=C([H])C([H])=C(OC([H])([H])[C@]([H])(N2C(=O)C([H])([H])C([H])([H])C([H])([H])C2=O)C([H])([H])C([H])([H])C2=C([H])C([H])=C(C([H])=C2[H])C(=O)N2C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])=C1[H])[N+]([O-])=O
[H]N(C1=C(C(=NO1)C([H])([H])[H])C([H])([H])[H])S(=O)(=O)C1=C([H])C([H])=C([H])C([H])=C1C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N=C(N([H])[H])N([H])C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])N(C(=O)[C@]([H])(N([H])C(=O)[C@@]2([H])N([H])C([H])([H])C3=C(C([H])=C([H])C([H])=C3[H])C2([H])[H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])[C@@]([H])(OC([H])([H])C2=C([H])C3=C([H])C([H])=C([H])C([H])=C3C([H])=C2[H])C1([H])[H]
[H]N(C1=NC(=C([H])C2=C1C(=O)N([H])C([H])=C2[H])C1=C(C([H])=C([H])N=C1[H])C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]N(N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C(=O)C1=NN(C(=C1C([H])([H])[H])C1=C([H])C([H])=C(Cl)C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]C1=C([H])C([H])=C(N2C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])C([H])([H])C3=C([H])C([H])=C4N(C(=O)OC([H])([H])C4=C3[H])C([H])([H])C([H])([H])N3C([H])([H])C([H])([H])C(=C(C4=C([H])C([H])=C(F)C([H])=C4[H])C4=C([H])C([H])=C(F)C([H])=C4[H])C([H])([H])C3([H])[H])C([H])([H])C2([H])[H])C(OC([H])([H])[H])=C1[H]
[H]N(C(=O)C1=C(N(N=C1[H])C1=C(Cl)C([H])=C(Cl)C([H])=C1[H])C1=C([H])C([H])=C(I)C([H])=C1[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
COC1=CC=C(C=C1)N1CCN(CC1)C(=O)CNC(=O)CCN1CCC2=C3C1CNC(=O)C3=CC=C2
[H]N(C(=O)C1=C([H])C([H])=C(OC([H])([H])[C@@]2([H])OC([H])([H])C([H])([H])C2([H])[H])C([H])=C1[H])C1=NC(=C([H])S1)C1=C(Cl)C([H])=C(Cl)C([H])=C1[H]
[H]N(C(=O)N([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC(N2C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])=C2N=NN(C2=N1)C([H])([H])C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C(=O)N([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]N([H])C1=NC(=C([H])C(=N1)C(=O)N([H])C([H])([H])C1=C(C([H])=C([H])C([H])=N1)C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1C([H])([H])[H]
[H]N([H])[C@]([H])(C(=O)N1C([H])([H])SC([H])([H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC([H])([H])[C@@]1([H])O[C@@]([H])(N2C([H])=NC3=C2N=C([H])N=C3N([H])[C@]2([H])C([H])([H])[C@@]3([H])N(C(=O)OC([H])([H])C4=C([H])C([H])=C([H])C([H])=C4Cl)[C@]2([H])C([H])([H])C3([H])[H])[C@]([H])(O[H])[C@]1([H])O[H]
[H]C1=C([H])C2=C(C([H])=C1Cl)C([H])([H])C([H])([H])C1=C2C([H])([H])C([H])([H])C(=O)N1C([H])([H])[H]
[H]N(C(=O)N1C([H])([H])C([H])([H])C([H])(OC2=C([H])C([H])=C([H])C([H])=C2Cl)C([H])([H])C1([H])[H])C1=C([H])C([H])=C([H])C(=C1[H])C1=NC([H])=C([H])N1[H]
[H]N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])[H])C([H])([H])C1=C([H])N=C([H])N1[H])C([H])([H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N([H])S(=O)(=O)C1=C([H])C(=C(N([H])C(=O)C([H])([H])[N+]2=C(C([H])=C(C([H])=C2C([H])(C([H])([H])[H])C([H])([H])[H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])=C1C(F)(F)F)S(=O)(=O)N([H])[H]
[H]N1[C@]2([H])C3=C(N(C4=C([H])C([H])=C(C([H])=C34)S(=O)(=O)C3=C([H])C4=C(SC([H])=C4[H])C([H])=C3[H])C([H])([H])[H])C([H])([H])[C@@]1([H])C([H])([H])C2([H])[H]
[H]N(C(=S)N([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1=C([H])N([H])C([H])=N1)C([H])([H])C([H])([H])[H]
[H]OC(=O)C1=C([H])C(=C([H])C([H])=C1[H])N1C([H])([H])C([H])([H])C([H])(C([H])([H])N2C([H])([H])C([H])([H])C([H])(OC3=C([H])C(Cl)=C(Cl)C([H])=C3[H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]N(C1=C([H])C2=C(C(=C1[H])C1=C([H])C([H])=C(F)C([H])=C1F)C([H])([H])N([H])C(=O)N2C1=C(Cl)C([H])=C([H])C([H])=C1Cl)C1([H])C([H])([H])C([H])([H])N([H])C([H])([H])C1([H])[H]
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[H]N1C(=C(C#N)[C@@]([H])(C2=C(Cl)C([H])=C([H])C([H])=C2[H])C(C(=O)OC([H])([H])[H])=C1C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=NC(=N1)N([H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])[H])C([H])([H])C1([H])[H])C([H])([H])C#N
[H]OC([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=NC(N([H])C3=C([H])C([H])=C(C([H])=C3[H])C(=O)N([H])[H])=C3N=C([H])N([H])C3=N2)C([H])([H])C1([H])[H]
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[H]N(C(=O)C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C(Cl)C([H])=C1[H])C1=C([H])C([H])=C2C([H])=C(C([H])([H])N(C([H])([H])[H])C([H])([H])C([H])([H])C3=C([H])C([H])=C([H])C([H])=C3[H])C([H])([H])C([H])([H])C2=C1[H]
CCC1=NC=C2C(CCC3=CC=C(C=C3)C(F)(F)F)N(CCN12)[C@@H](C(=O)NC)C1=CC=CC=C1
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[H]OC(=O)C([H])([H])[C@@]1([H])C2=C([H])C([H])=C(OC([H])([H])C([H])([H])C([H])([H])OC3=C([H])C([H])=C(OC([H])([H])[H])C([H])=C3[H])C([H])=C2C([H])([H])C1([H])[H]
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[H]C1=C([H])C(OC(=O)N2C([H])([H])C([H])([H])[N@]3C([H])([H])C([H])([H])[C@]2([H])C([H])([H])C3([H])[H])=C([H])C(F)=C1[H]
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[H]OC([H])([H])C1(C([H])([H])O[C@]2(N(C(=O)C3=C([H])C([H])=C([H])C([H])=C23)C([H])([H])C2=C([H])C([H])=C(C([H])=C2[H])C([H])([H])[H])C2=C([H])C([H])=C(Cl)C([H])=C2[H])C([H])([H])C1([H])[H]
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[H]N([H])C(C(=O)N([H])[C@@]([H])(C(=O)N([H])[C@@]([H])(N([H])C(=O)C([H])([H])[H])C([H])([H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H])C([H])([H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H])(C([H])([H])[H])C([H])([H])[H]
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[H]OC1=C([H])C([H])=C([H])C(=C1[H])[C@]1(C([H])([H])[H])C([H])([H])[C@@]2([H])N(C([H])([H])C([H])([H])N(C([H])([H])C3=C([H])C([H])=C4C([H])=C([H])C([H])=C([H])C4=C3[H])C2([H])[H])C([H])([H])[C@]1([H])C([H])([H])[H]
[H]N(C([H])([H])C1=C([H])C2=C(C([H])=C1[H])C([H])([H])[C@@]([H])(N(C(=O)C1=C([H])C([H])=C(OC([H])([H])C3([H])C([H])([H])C3([H])[H])C([H])=C1[H])C([H])([H])[H])C2([H])[H])[C@@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])[H]
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[H]N(C(=O)[C@]1([H])N(C([H])([H])C2=C([H])C(C#N)=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C1([H])[H])[C@@]1([H])[C@@]2([H])C([H])([H])[C@]3([H])C([H])([H])[C@]([H])(C2([H])[H])C([H])([H])[C@@]1([H])C3([H])[H]
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[H]OC1=C([H])C([H])=C([H])C(\C([H])=N\N=C(/N([H])[H])C2=NON=C2N([H])[H])=C1[H]
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[H]N(C(=O)N([H])C1=C(C([H])=C([H])C([H])=C1C([H])(C([H])([H])[H])C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])C1=NN(N([H])N1[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
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[H]N([H])C1=NC([H])=C(C([H])=N1)C1=NC2=C(SC([H])=C2[H])C(=N1)N1C([H])([H])[C@@]2([H])O[C@]([H])(C([H])([H])C2([H])[H])C1([H])[H]
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[H]N(C1=C2C([H])=NN(C2=C([H])C(=C1[H])C([H])([H])[H])C1=C([H])C([H])=C(F)C([H])=C1[H])[C@]([H])(C([H])([H])[H])C([H])([H])N([H])S(=O)(=O)C1=C(C([H])=C(C([H])=C1C([H])([H])[H])C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)N([H])S(=O)(=O)C1=C(C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1N(C(=O)C2(C1=O)C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
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[H]C1=NC([H])=C(C([H])=C1[H])C([H])([H])N(C(=O)C([H])([H])C1=C([H])C([H])=C([H])C(=C1[H])C(F)(F)F)[C@@]([H])(C1=NC2=C([H])C([H])=C([H])C([H])=C2C(=O)N1C1=C([H])C([H])=C(OC([H])([H])C([H])([H])[H])C([H])=C1[H])C([H])([H])[H]
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[H]OC([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C(\[H])=C(\C1=C([H])N=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N([C@]([H])(C([H])([H])[H])C([H])([H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H])S(=O)(=O)C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)C1=C([H])C2=C([H])C([H])=C([H])C([H])=C2C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])(N(C(=O)C([H])([H])C([H])([H])[H])C2=C([H])C([H])=C([H])C([H])=C2OC([H])([H])[H])C([H])([H])C1([H])[H]
[H]N1N=C2C3=C(OC4=C2C(=C([H])C([H])=C4[H])C1=O)C([H])=C([H])C(=C3[H])C([H])([H])N(C([H])(C([H])([H])[H])C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N1C(=O)N(C([H])([H])C2=C([H])C(=C([H])C([H])=C2[H])C([H])([H])N2C([H])([H])C([H])([H])N(C3=C([H])C([H])=C([H])C([H])=C3OC([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C2([H])[H])C([H])([H])C1=O
[H]C1=C([H])C(=C2N(C(=O)OC([H])([H])C2=C1[H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])S(=O)(=O)C1=C([H])C(Br)=C([H])C([H])=C1OC([H])([H])[H])C([H])([H])[H]
[H]OC(=O)C([H])([H])C([H])([H])C(=O)N([H])C1=NN(C(=C1[H])C1=NC2=C(N1[H])N(C(=O)N(C2=O)C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])C(N(C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[H])=C2C([H])=C(C(OC3=C(OC([H])([H])[H])C([H])=C(C([H])=C3OC([H])([H])[H])C([H])([H])OC([H])([H])[H])=NC2=C1[H])C([H])([H])[H]
[H]O[C@]([H])(C([H])([H])OC1=C([H])C([H])=C([H])C2=C1[C@@]([H])(C(=O)N2[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])N([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(OC2=NC([H])=C(C([H])=C2[H])C(=O)N([H])[H])C([H])=C1[H]
[H]OC(=O)C([H])([H])[C@]([H])(O[H])C([H])([H])[C@]([H])(O[H])C([H])([H])OC1=C(C(=NN1C1=C([H])C([H])=C(F)C([H])=C1[H])C(=O)N(C([H])([H])[H])[C@@]([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N([H])C(=O)C1=C(OC([H])([H])[H])C([H])=C2N=C([H])C([H])=C(OC3=C([H])C4=C(C([H])=C3[H])N(C(=O)N([H])C3=C([H])C([H])=C(Cl)C([H])=C3[H])C([H])([H])C([H])([H])O4)C2=C1[H]
[H]C1=NC([H])=C(OC([H])([H])[C@@]2([H])N(C([H])([H])[H])C([H])([H])C([H])([H])C2([H])[H])C([H])=C1[H]
[H]N([H])C1=NC(N([H])S(=O)(=O)C2=C([H])C([H])=C(C([H])=C2[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])=C(OC2=C([H])C([H])=C([H])C([H])=C2OC([H])([H])[H])C(OC([H])([H])C([H])([H])OC2=NC([H])=C(Br)C([H])=N2)=N1
[H]OC([H])([H])C([H])([H])C([H])([H])C([H])([H])N1C2=C(C([H])=C([H])C([H])=C2[H])C2=C1C1=C(C3=C(C([H])=C([H])N3C([H])([H])[H])C([H])=C1C([H])([H])[H])C1=C2C(=O)N([H])C1=O
[H]C1=C([H])C(=C([H])C([H])=C1Cl)C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])[H])[C@@]1([H])C([H])([H])N(C(=O)N2C([H])([H])C([H])([H])[C@]([H])(N(C(=O)C3=C([H])C([H])=C(C([H])=C3[H])C3=C([H])C([H])=C(C([H])=C3[H])C(F)(F)F)C([H])([H])[H])C2([H])[H])C([H])([H])C1([H])[H]
[H]N(C1=NC(=NC2=C([H])C(OC([H])([H])[H])=C([H])C([H])=C12)N1C([H])([H])C([H])([H])C([H])(N2C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]O[C@@]([H])(C([H])([H])OC1=C([H])C2=C(C([H])=C1[H])N(C(=C2C(=O)OC([H])([H])C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])N1C([H])([H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1=C([H])N=C([H])C([H])=C1[H]
[H]ON([H])C(=O)C1=C(N(C([H])([H])[H])S(=O)(=O)C2=C([H])C([H])=C(OC3=C([H])C([H])=C(Cl)C([H])=C3[H])C([H])=C2[H])C(=C([H])C([H])=C1[H])C([H])([H])N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N1C([H])([H])C([H])([H])C([H])(N(C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2C(F)(F)F)C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N(C(=O)C1=C([H])C([H])=NC([H])=C1[H])C1=C([H])C(=C([H])C2=C1[C@]1([H])C([H])=C(C([H])([H])[H])C([H])([H])C([H])([H])[C@@]1([H])C(O2)(C([H])([H])[H])C([H])([H])[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]N1C(=NC2=C1C(=O)N(C(=O)N2C([H])([H])C1=C([H])C([H])=C([H])O1)C([H])([H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C1=C([H])C(OC(=O)C([H])([H])[H])=C(SC([H])([H])C#CC([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])=C1[H]
[H]OC(=O)C1=C([H])C([H])=C(C#CC2=C([H])C([H])=C(C([H])=C2[H])S(=O)(=O)N([H])[C@@]([H])(C(=O)O[H])C([H])([H])C2=C([H])N([H])C3=C2C([H])=C([H])C([H])=C3[H])C([H])=C1[H]
[H]N(C(=O)OC([H])([H])C([H])([H])[C@]([H])(N(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])[H]
[H]OC(=O)C([H])([H])[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@]([H])(N([H])C(=O)C([H])([H])[H])C([H])([H])C1=C(C(=C(C(=C1C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)O[H])C([H])([H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H])[C@@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])[H])[C@@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])[H]
[H]N([H])C1=C([H])C([H])=C(C([H])=C1C(=O)N([H])C([H])([H])C([H])([H])[C@@]([H])(N1C([H])=NC([H])=C1[H])C([H])([H])[H])C([H])([H])[H]
[H]N1C(=NC2=C1C([H])=C([H])C(F)=C2[H])N1C([H])([H])C([H])([H])N(C2=NC([H])=C([H])C([H])=C2C(F)(F)F)C([H])([H])C1([H])[H]
[H]N1C2=NC([H])=C([H])C(=C2C([H])=C1C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])N(C([H])([H])[H])S(=O)(=O)C([H])([H])[H]
[H]C1=NN(C2=C1C([H])([H])[C@@]1(C(=C2[H])C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=NC([H])=C2[H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C(F)C([H])=C1[H])C1=C([H])C([H])=C(F)C([H])=C1[H]
CC1=C2C(=O)NCC2=CC=C1OCCCCN1CCN(CC1)C1=CC=CC2=CC(F)=CC=C12
[H]N(C(=O)C([H])([H])C([H])([H])C(=O)C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])[C@@]([H])(C([H])([H])N(C(=O)C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1OC([H])([H])[H])C([H])([H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H]
[H]C1=C([H])C([H])=C(C(SC2=C([H])C(F)=C(Cl)C([H])=C2[N+]([O-])=O)=C1[H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)N(C([H])([H])[H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])S(=O)(=O)C([H])([H])[H])C1([H])C([H])([H])C([H])([H])N(C2=C([H])C([H])=C(F)C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N1C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])OC([H])(C2=C([H])C([H])=C([H])C([H])=C2[H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]OC1=C([H])C(OC([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C(=O)OC([H])(C([H])([H])O[H])C([H])([H])O[H])=C([H])C(=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]O[C@@]([H])(C([H])([H])N1C([H])([H])C([H])([H])N(C2=C([H])C([H])=C([H])C([H])=C2OC([H])([H])[H])C([H])([H])C1([H])[H])C([H])([H])C([H])([H])N([H])C(=O)C1=C([H])C2=C(N1[H])C([H])=C([H])C([H])=C2[H]
[H][C@]12CN(C(C)=O)[C@]([H])(CN1CC1=COC3=CC(OC4=NC5=NC=CC=C5S4)=CC=C13)C2
[H]N(C(=O)C1=C([H])C2=C(N1[H])C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])[C@]([H])(F)C([H])([H])N1C([H])([H])C([H])([H])N(C2=C(OC([H])([H])[H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
NC(=O)C1=C2N=C(C3=CC=CC=C3Cl)C3=C(NC2=NN1)C=CC(=C3)[N+]([O-])=O
[H]C1=C([H])C(=C([H])C([H])=C1F)[S@@](=O)C1([H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])N(C(=O)C2([H])C([H])([H])C([H])([H])N(C(=O)C([H])([H])[H])C([H])([H])C2([H])[H])C2=C([H])C([H])=C(Cl)C(Cl)=C2[H])C([H])([H])C1([H])[H]
Cl.[H][C@@]12CCC3=CC=CC=C3[C@]1([H])CCN(CC1=CC=C(C=C1)C(C)(C)C)C2
NS(=O)(=O)C1=CC=C(C=C1)N1N=C(CCO)C=C1C1=CC=CC=C1
[H]N(C1=C([H])C([H])=C(C([H])=C1[H])C(=O)C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C(C#N)C([H])=NN2C([H])=C(C(=O)OC([H])([H])C([H])([H])[H])C(=C12)C([H])([H])[H]
[H]N(C(=O)C1=C(N(C2=C([H])C(OC([H])(C([H])([H])[H])C([H])([H])[H])=C([H])C([H])=C12)C([H])([H])C1=NC([H])=C([H])C([H])=C1[H])C(=O)OC([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(F)C(F)=C1[H]
[H]O[C@@]([H])(C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])[C@]([H])(O[H])[C@@]([H])(N([H])C(=O)[C@@]([H])(O[C@]([H])(C(=O)N1C([H])([H])C([H])([H])C([H])(OC([H])([H])OC([H])([H])[H])C([H])([H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H])C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N1C2=C([H])C([H])=C(Cl)C([H])=C2C(C(=O)C(=O)N(C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])=C1C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC(=O)C1=C([H])C2=C([H])C(Br)=C([H])C(N([H])C([H])([H])C3([H])C([H])([H])C([H])([H])N([H])C([H])([H])C3([H])[H])=C2O1
[H]OC(=O)C([H])([H])C([H])([H])[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])[H])C([H])([H])C1=C([H])C([H])=C(F)C([H])=C1[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C(=O)O[H]
[H]N([H])C1=C([H])C(=C(N=C1[H])C1=C2N=C(C([H])=C(N(C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[H])N2N=C1C([H])([H])[H])C([H])([H])[H])C([H])([H])[H]
[H]N([H])[C@@]([H])(C(=O)N1C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C([H])([H])C(=O)N([H])C([H])([H])C1=C([H])C(Cl)=C([H])C([H])=C1N1N=C([H])N=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C1=C([H])C(C2=NN=C(N2C([H])([H])[H])[C@@]23C([H])([H])C([H])([H])[C@@](C([H])([H])C([H])([H])S(=O)(=O)C4=C([H])C([H])=C(F)C([H])=C4[H])(C([H])([H])C2([H])[H])C([H])([H])C3([H])[H])=C(C([H])=C1[H])C(F)(F)F
[H]C1=C(C2=C([H])C([H])=C(C([H])=C2C1([H])[H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])C1=C([H])C([H])=NC([H])=C1[H]
[H]N([H])S(=O)(=O)[C@]([H])(C([H])([H])[H])S(=O)(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]OC(=O)C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1OC([H])([H])C([H])([H])[C@]1([H])OC2=C([H])C([H])=C([H])C([H])=C2N(C1=O)C([H])([H])C([H])([H])SC([H])([H])C([H])([H])C([H])([H])[H]
[H]N(C1=NC2=C([H])C([H])=C([H])C([H])=C2C(=C1[H])C(F)(F)F)[C@@]1([H])C([H])([H])C([H])([H])C([H])([H])[C@]([H])(N([H])C([H])([H])C2=C([H])SC([H])=C2[H])C1([H])[H]
[H]N([H])C([H])([H])C(=O)N([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)N([H])[H]
[H]OC(=O)C([H])([H])N1C([H])([H])C([H])([H])[C@@]2(C([H])([H])C1([H])[H])C([H])([H])C([H])([H])[C@]([H])(C(=O)N1C([H])([H])C([H])([H])N(C3=C([H])C([H])=NC([H])=C3[H])C([H])([H])C1([H])[H])C([H])([H])C2([H])[H]
[H]N(C([H])([H])[C@@]1([H])[C@@]2([H])C([H])([H])[C@]3([H])C([H])([H])[C@@]([H])(C([H])([H])[C@@]1([H])C3([H])[H])C2([H])[H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C2=C(F)C([H])=C(Cl)C([H])=C2[H])C([H])([H])C1([H])[H]
[H]OC(=O)C(=O)N([H])C1=C(C(=O)O[H])C2=C(S1)C([H])([H])[C@]([H])(O[H])C([H])([H])C2([H])[H]
[H]N(C(=O)N([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C1=NC2=C([H])C([H])=C([H])C([H])=C2N2N1N=C(C2=O)C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N1C(=NC(C2=C([H])C([H])=C(F)C([H])=C2[H])(C2=C([H])C([H])=C(F)C([H])=C2[H])[C@]1([H])C([H])([H])C([H])([H])[H])C1=NC([H])=C([H])C(C#N)=C1[H]
[H]N(C1=NC2=C(C([H])=N1)C([H])=C([H])C(=O)N2C([H])([H])C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])N1C([H])=C([H])C([H])=C1[H]
[H]C1=C([H])C2=NN=C([H])C(C(=O)N3C([H])([H])C([H])([H])C([H])(N4C([H])([H])C([H])([H])[C@]([H])(C([H])([H])C5=C([H])C(Cl)=C(Cl)C([H])=C5[H])[C@]([H])(OC([H])([H])[H])C4([H])[H])C([H])([H])C3([H])[H])=C2C([H])=C1[H]
[H]OC(C1=C([H])C([H])=C([H])C([H])=C1[H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C1([H])C([H])([H])C([H])([H])N(C(=S)N([H])C2=C([H])C(=C(OC([H])([H])[H])C([H])=C2[H])C(F)(F)F)C([H])([H])C1([H])[H]
[H]N(C1=NC2=C(C([H])=C([H])C([H])=C2N2C([H])=NC([H])=C12)C1=NN=C([H])N1[H])C1=C([H])C([H])=C([H])C([H])=C1F
[H]N(C(=O)C([H])([H])N1C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2F)C([H])([H])C1([H])[H])[C@@]1([H])C2=C(Br)SC(Br)=C2[C@@]([H])(Cl)C1([H])[H]
[H]N1C([H])([H])C([H])([H])[C@]([H])(N(C(=O)C2=C(Cl)C(Cl)=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C2([H])C([H])([H])C2([H])[H])C1([H])[H]
[H]C1=C([H])C2=C(C([H])=C1[H])C([H])([H])[C@]([H])(N2C(=O)C([H])([H])C([H])([H])N1C([H])([H])C2=C(C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H])C(=O)N(C([H])([H])[H])C([H])([H])[H]
[H]N([H])C1=NC2=C(N(C(=C2[H])C([H])([H])[H])C([H])([H])C2=C([H])C([H])=C(F)C([H])=C2[H])C(=O)N1[H]
[H]OC(=O)C1=C([H])C([H])=C([H])C(=N1)C(=O)N([H])C1=C(C([H])=C(C(Cl)=C1[H])S(=O)(=O)N([H])[H])S(=O)(=O)N([H])[H]
[H]N1C(=O)N([H])[C@@]2(C1=O)C1=C(C([H])=C([H])C(=C1OC([H])([H])C2([H])[H])C([H])([H])[H])C([H])([H])[H]
[H]N([H])C1=NC2=C(S1)C([H])([H])[C@@]([H])(N(C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[C@@]1([H])C([H])([H])C([H])([H])[C@]([H])(N([H])C(=O)C(\[H])=C(/[H])C3=C(Cl)C([H])=C([H])C([H])=C3[H])C([H])([H])C1([H])[H])C([H])([H])C2([H])[H]
[H]N(C(=O)C([H])([H])SC1=NC2=C(SC([H])([H])C2([H])[H])C(=O)N1C1=C([H])C([H])=C([H])C([H])=C1OC([H])([H])[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]C1=C2N(C([H])([H])C([H])([H])[H])C([H])([H])[C@@]3([H])[C@@]4([H])C([H])([H])C([H])([H])[C@]([H])(C(=O)N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H])[C@@]4(C([H])([H])[H])C([H])([H])C([H])([H])[C@]3([H])[C@@]2(C([H])([H])[H])C([H])([H])C([H])([H])C1=O
[H]N([H])S(=O)(=O)OC1=C([H])C([H])=C(OC2=C([H])C([H])=C([H])C([H])=C2[H])C([H])=C1[H]
[H]C1=C([H])C(=C([H])C([H])=C1SC([H])([H])[H])C([H])([H])N1C([H])([H])C([H])([H])N(C(=O)C2=C([H])C([H])=C(C([H])=C2[H])[N+]([O-])=O)C([H])([H])C1([H])[H]
[H]OC1=C([H])C([H])=C([H])C([H])=C1C(=O)N([H])\N=C(/[H])C1=C([H])C(OC([H])([H])[H])=C(OC([H])([H])C(=O)N([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])=C1[H]
[H]N(C(=O)C1=C(F)C([H])=C(F)C([H])=C1F)C1=C([H])C([H])=C2OC([H])=C(C2=N1)C1([H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H]
[H]C1=NC(=C([H])C([H])=C1[H])C1=NC([H])=C(OC([H])([H])[H])C(OC2=C([H])C([H])=C(Cl)C3=C([H])C([H])=C([H])C([H])=C23)=N1
[H]OC(=O)C([H])([H])N(C1=C([H])C([H])=C2N(C([H])([H])[H])C([H])([H])[C@](OC2=C1[H])(C([H])([H])[H])C([H])([H])OC1=C([H])C([H])=C(C([H])=C1[H])C(=N[H])N([H])[H])C([H])([H])C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]N(C1=C(C(=O)OC2=C([H])C([H])=C([H])C([H])=C12)C([H])([H])C1=C(C([H])=C([H])C([H])=C1[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
CCCCCCNC1=C2C3=CC=C(OC4=CC=C(C=C4)C(C)C)C4=CC=CC(C2=NC1=O)=C34
[H]N([H])S(=O)(=O)C1=C([H])C([H])=C(C([H])=C1[H])C1=C(C2=C([H])C([H])=C(F)C(F)=C2[H])C([H])([H])C2(C([H])([H])C2([H])[H])C1([H])[H]
[H]OC(=O)C([H])([H])C([H])([H])C([H])([H])SC1=C(C([H])=C2N(C(=C(C2=C1[H])C([H])([H])C(=O)N([H])[H])C([H])([H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)[C@@]1([H])C([H])([H])N([H])C([H])([H])C([H])([H])[C@]1([H])C1=C([H])C([H])=C([H])C([H])=C1F)[C@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])C1=C([H])C(SC2=C([H])C([H])=C(Cl)C([H])=C2[H])=NN(C1=O)C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]C1=C([H])C(C#N)=C([H])C(=C1[H])N1N=NC(=N1)[C@]1([H])N(C(=O)C2([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N1[C@]2([H])C([H])([H])C([H])([H])[C@@]1([H])[C@@]([H])(C(=O)OC([H])([H])[H])[C@@]([H])(OC(=O)C1=C([H])C([H])=C([H])C([H])=C1[H])C2([H])[H]
[H]N=C(N([H])C1=C([H])C(=C([H])C([H])=C1[H])C([H])([H])C([H])([H])[H])N1C([H])([H])C([H])([H])C([H])(C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]O[C@@]([H])(C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])[C@]([H])(O[H])[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
CS(=O)(=O)C1=CC=C(C(=O)N2CCOC3=CC=C(C=C3C2)C2=CC=C3N=CNC3=C2)C(Br)=C1
[H]N(C(=O)C([H])([H])N1C(=O)N(C2=C1C([H])=C([H])C([H])=C2[H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])[C@@]([H])(OC2=C([H])C(OC([H])([H])[H])=C([H])C([H])=C2C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]C1=NC(=C([H])N1C([H])([H])[H])S(=O)(=O)N(C([H])([H])C([H])([H])N(C1=C([H])C([H])=C(C#N)C([H])=C1[H])C([H])([H])C1=C([H])N=C([H])N1C([H])([H])[H])C([H])([H])C1([H])C([H])([H])C([H])([H])N(C(=O)OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N(C(=O)C([H])([H])SC1=NN=C(S1)C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC2=C([H])C([H])=C([H])C([H])=C2S1
[H]N(C(=O)C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])N1C([H])([H])C([H])([H])[C@@]([H])(N(C(=O)C([H])([H])[H])C([H])([H])[H])C1([H])[H]
[H]OC1=NC2=C([H])C([H])=C([H])C([H])=C2C2=C([H])C(=NN12)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C1=C(C(=O)OC([H])([H])C([H])([H])[H])C(=O)C2=C([H])C(OC([H])([H])[H])=C([H])C([H])=C12
[H]OC1=C([H])C([H])=C(C([H])=C1O[H])C1=C([H])C(=O)C2=C(O1)C([H])=C(OC([H])([H])[H])C(OC([H])([H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])=C2OC([H])([H])[H]
[H]C1=NC2=C([H])C(OC([H])([H])C([H])([H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H])=C([H])C([H])=C2N1C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@]([H])(N([H])[H])C(=O)N1C([H])([H])C2=C(C([H])=C([H])C([H])=C2[H])[C@@]1([H])P(=O)(OC1=C([H])C([H])=C(N([H])C(=O)C([H])([H])[H])C([H])=C1[H])OC1=C([H])C([H])=C(N([H])C(=O)C([H])([H])[H])C([H])=C1[H]
[H]N(C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C(=O)OC([H])([H])[H])S(=O)(=O)C1=C([H])C2=C([H])C([H])=C([H])C([H])=C2C([H])=C1[H]
[C-]#[N+]C1(CCN(CC2=CC=C(C=C2)C2=NN=C3N2C2=CC=CN=C2NC2=C3C=CC=C2)CC1)C1=CC=CC=C1
[H]C1=C([H])C([H])=C2N(C(=O)C([H])([H])SC3=NN=NN3C3([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C3([H])[H])C3=C([H])C([H])=C([H])C([H])=C3SC2=C1[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C2=C([H])C(Br)=C([H])C(OC([H])([H])[H])=C2OC1=O
[H]C1=NN(N=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1C([H])([H])C2(C1([H])[H])C([H])([H])C([H])([H])N(C(=O)C([H])([H])C1=C([H])N3C([H])=C(Cl)C([H])=C([H])C3=N1)C([H])([H])C2([H])[H]
[H]OC([H])([H])[C@@]1([H])N([H])[C@@]([H])(C2=C([H])C3=C(N2[H])C(=O)N([H])C([H])=N3)[C@]([H])(O[H])[C@]1([H])O[H]
[H]C1=NC2=C([H])C(=C([H])C(C3=C([H])C([H])=C([H])C([H])=C3[H])=C2C([H])=C1N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H])C(F)(F)F
[H]OC1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C(S1)C(=O)C1=C([H])C([H])=C([H])C(O[H])=C1[H]
[H]N([H])C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)N([H])C1=NN=C(S1)S(=O)(=O)N([H])[H]
[H]C1=NC(=C([H])C([H])=C1[H])C([H])([H])N(C([H])([H])C1=NC([H])=C([H])C([H])=C1[H])[C@@]([H])(C(=O)N1C([H])([H])C([H])([H])N(C2=C([H])C([H])=C([H])C([H])=C2C(=O)C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C(Cl)C([H])=C1Cl
[H]OC([H])([H])[C@@]([H])(C(=O)O[C@@]1([H])C([H])([H])[C@]2([H])N(C(=N[H])C([H])([H])[H])[C@]([H])(C1([H])[H])[C@@]1([H])O[C@@]21[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N1C([H])=C([H])C2=C3N(C([H])=NC3=C([H])N=C12)C1([H])C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])S(=O)(=O)C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N([H])C1=NC2=C(C([H])=C([H])C([H])=C2[H])C2=C([H])N(N=C12)C1=C([H])C([H])=C([H])C(F)=C1[H]
[H]O[C@]1([H])C([H])([H])N(C([H])([H])C2=C([H])C3=C([H])C([H])=C([H])C(=C3N=C2[H])C([H])([H])N([H])C(=O)C2=C([H])C([H])=C(C([H])=C2[H])C2=C([H])C([H])=C(F)C([H])=C2[H])C([H])([H])C1([H])[H]
[H]O[C@]1([H])N(C(=N[H])N([H])[H])C([H])([H])C([H])([H])C([H])([H])[C@]1([H])N([H])C(=O)C([H])([H])N1C(=O)[C@@]([H])(N2C(=O)C3=C(C([H])=C([H])C([H])=C3[H])C([H])([H])S2(=O)=O)C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]C1=C(C([H])=C([H])C(=N1)C([H])([H])[H])C1=NN=C(SC([H])([H])C([H])([H])C([H])([H])N2C([H])([H])C([H])([H])C3=C([H])C([H])=C4OC(=NC4=C3C([H])([H])C2([H])[H])C(F)(F)F)N1C([H])([H])[H]
[H]N([H])C1=NC(=C([H])C(=N1)C(=O)N([H])C([H])([H])C1=C(C([H])=C([H])C([H])=N1)C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1OC([H])([H])C([H])([H])[H]
[H]C1=NN(C2=C1C([H])([H])C([H])([H])C([H])([H])C1=C(SC(=C21)C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]OC(=O)C([H])([H])OC1=C([H])C([H])=C([H])N2C1=C(C(=C2C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])[H])C([H])([H])C(=O)N([H])[H]
[H]ON([H])C(=O)C([H])([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])C([H])([H])C([H])([H])C1=NC([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]ON([H])C(=O)[C@@]([H])(C([H])([H])O[H])[C@]([H])(C(=O)N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]N1C(SC([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N(C(=O)OC([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])=NC(=C1C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C1=C([H])C(OC([H])([H])C([H])([H])[H])=C(Cl)C([H])=C1Cl)C1=C(C#N)C([H])=NC2=C1SC(=C2[H])C1=C([H])SC(=C1[H])C([H])([H])N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N([H])C(=O)C([H])([H])N(C1=NC(=NS1)N1C([H])=NC([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])N([H])C([H])([H])C1=C([H])C([H])=C2OC([H])([H])OC2=C1[H]
[H]ON1C2=C(C(=NN2C([H])([H])C(=O)OC([H])([H])C([H])([H])[H])C([H])([H])[H])C(=O)C2=C([H])C(Cl)=C([H])C([H])=C12
[H]N=C(N([H])[H])N([H])C([H])([H])C([H])([H])C([H])([H])C(=O)N([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@]1([H])N([H])C(=O)[C@@]([H])(N([H])C1=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=O)C([H])([H])C([H])([H])C([H])([H])N([H])C(=N[H])N([H])[H]
[H]ON([H])C(=O)C(\[H])=C(/[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC1=C2N=C([H])C([H])=C([H])C2=C(Cl)C([H])=C1[C@@]([H])(N([H])C(=O)C([H])([H])C([H])([H])[H])C1=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]N([H])C(=O)C1=C2N=C(N([H])C2=C([H])C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])[C@@]1([H])N(C([H])([H])C([H])([H])C1([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]OC(=O)[C@@]([H])(N([H])C(=O)C1=C([H])C2=C([H])C([H])=C([H])C([H])=C2C([H])=C1N([H])C(=O)N([H])C1=C(C([H])=C(C([H])=C1C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]C1=NC(=C([H])C([H])=C1[H])C1=NN(N=N1)C1=C([H])C(F)=C([H])C(=C1[H])C1=C([H])N=C(OC([H])([H])[H])N=C1[H]
[H]N(C1=C([H])C2=C(C([H])=C1[H])C1=C(OC([H])([H])[H])C([H])=C([H])C([H])=C1O[C@]2([H])C1=C([H])C([H])=C([H])C([H])=C1[H])S(=O)(=O)C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC1=C([H])C2=C(C([H])=C(N2[H])C2=C([H])N=C([H])C(=N2)C2=C([H])C([H])=C(C([H])=C2[H])S(=O)(=O)C([H])([H])[H])C([H])=C1[H]
[H]N(C(=O)C1=C([H])C([H])=C(OC([H])([H])C2=C([H])C([H])=NC3=C([H])C([H])=C([H])C([H])=C23)C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C1=NN([H])C(=S)N1[H]
[H]N(C(=O)C([H])([H])[C@]1([H])N(C([H])([H])C([H])([H])N([H])C1=O)S(=O)(=O)C1=C([H])C2=C(S1)C([H])=C([H])C(Cl)=C2[H])[C@@]1([H])C2=C(C([H])=C(C([H])=C2[H])C([H])([H])N2C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C([H])([H])C1([H])[H]
[H]N([H])C(=O)[C@@]([H])(N(C(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C(C([H])=C([H])C([H])=C1[H])C1=NN([H])N=N1)C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)C([H])([H])N(C(=O)C1=C([H])C2=C(S1)C([H])([H])C([H])([H])C2([H])[H])C([H])([H])[H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]OC(=O)C([H])([H])C([H])([H])C1=C([H])C([H])=C(OC([H])([H])C([H])([H])[C@]([H])(OC2=C(C([H])=C(C([H])=C2[H])C([H])([H])C([H])([H])[H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])[H])C([H])=C1C([H])([H])[H]
[H]N1C([H])([H])[C@@]2([H])C([H])([H])N(C3=C([H])N=C([H])C(OC([H])([H])C([H])([H])[H])=C3[H])C([H])([H])[C@@]2([H])C1([H])[H]
[H]C1=C([H])C(=C([H])C([H])=C1C([H])([H])N1C([H])([H])C([H])([H])N(C(=O)C([H])([H])SC2=NN=NN2C2([H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N([H])C(=NC(=O)C1=C([H])C2=C(C([H])=C([H])C([H])=C2S1)C([H])([H])C([H])([H])[H])N([H])[H]
[H]C1=C([H])C([H])=C(C(SC2=C([H])C([H])=C(C([H])=C2[H])C(F)(F)F)=C1[H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)C([H])([H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])C1=C([H])N(C([H])=N1)C1([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
CC1=NC2=CC=C(N[C@H]3CC[C@H](O)CC3)C=C2N2C1=NN=C2C1=CC=CC=C1Cl
CC1=C(OC2=CC=C(C=C2)N2C=NC=N2)N=CN=C1N1C2CC3CC1CC(C2)N3C(=O)OC(C)(C)C
[H]N(C(=O)N([H])C([H])([H])C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC(N2C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])=C2C(=N1)C([H])([H])OC2([H])[H]
[H]C1=C(SC(=C1[H])C([H])([H])[H])C(=O)N1C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C1=NC(=NO1)C1=C([H])C(=C([H])C([H])=C1[H])C([H])([H])[H]