[H]OC1=C2\C(=C(/[H])N(C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H])C(=O)O[C@]([H])(C([H])([H])OC([H])([H])[H])[C@@]2(C2=C(C1=O)[C@@]1([H])C([H])([H])C([H])([H])[C@]([H])(O[H])[C@@]1(C([H])([H])[H])C([H])([H])[C@@]2([H])OC(=O)C([H])([H])[H])C([H])([H])[H]
[H]OC1=C([H])C(=C([H])C([H])=C1[H])C1=NC2=C(N=C1[H])N=C(N=C2N([H])[H])N([H])[H]
[H]N([H])C1=NC2=C(N=C(C([H])=N2)C2=C([H])C([H])=C([H])C3=C2C([H])=C([H])N3[H])C(=N1)N([H])[H]
[H]OC1=C([H])C(=C([H])C([H])=C1[H])C1=NC2=C(N=C1C1=C([H])C([H])=C([H])C(O[H])=C1[H])C(=NC(=N2)N([H])[H])N([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C1=C2OC(=C([H])C(=O)C2=C([H])C([H])=C1[H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]C1=C2C3=C(O1)C(=O)C1=C([C@]([H])(OC(=O)C([H])([H])[H])C([H])([H])[C@@]4(C(=O)C([H])([H])C([H])([H])[C@@]14[H])C([H])([H])[H])[C@@]3(C([H])([H])[H])[C@]([H])(OC2=O)C([H])([H])OC([H])([H])[H]
[H]N1N=C([H])C2=C1C([H])=C([H])C([H])=C2C1=NC(N2C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])=C2SC(=C([H])C2=N1)C([H])([H])N1C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])S(=O)(=O)C([H])([H])[H]
[H]N(C1=C2N=C([H])N([H])C2=NC([H])=N1)[C@]([H])(C1=NC2=C([H])C([H])=C([H])C(Cl)=C2C(=O)N1C1=C([H])C(F)=C([H])C(F)=C1[H])C([H])([H])C([H])([H])[H]
[H]N(C1=C2N=C([H])N([H])C2=NC([H])=N1)[C@]([H])(C1=NC2=C([H])C([H])=C([H])C([H])=C2C(=O)N1C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])[H]
[H]N(C1=C2N=C([H])N([H])C2=NC([H])=N1)[C@]([H])(C1=NC2=C([H])C([H])=C([H])C(Cl)=C2C(=O)N1C1=C(F)C([H])=C([H])C([H])=C1F)C([H])([H])C([H])([H])[H]
[H]N(C1=C2N=C([H])N([H])C2=NC([H])=N1)[C@]([H])(C1=NC2=C([H])C([H])=C([H])C(=C2C(=O)N1C1=C([H])C(F)=C([H])C(F)=C1[H])C([H])([H])[H])C([H])([H])C([H])([H])[H]
[H]OC1=C([H])C([H])=C([H])C([H])=C1C1=C([H])C([H])=C(O1)C(\[H])=C1/SC(=O)N([H])C1=O
[H]\C(=N/N(C([H])([H])[H])S(=O)(=O)C1=C([H])C(=C([H])C([H])=C1C([H])([H])[H])[N+]([O-])=O)C1=C([H])N=C([H])C2=C([H])C([H])=C([H])C([H])=C12
[H]\C(=N/N(C([H])([H])[H])S(=O)(=O)C1=C([H])C(=C([H])C([H])=C1C([H])([H])[H])[N+]([O-])=O)C1=C([H])N=C2C([H])=C([H])C([H])=C([H])N12
[H]\C(=N/N(C([H])([H])[H])S(=O)(=O)C1=C([H])C(=C([H])C([H])=C1C([H])([H])[H])[N+]([O-])=O)C1=C([H])N=C([H])C2=C([H])C([H])=C(Br)C([H])=C12
[H]\C(=N/N(C([H])([H])[H])S(=O)(=O)C1=C(C([H])=C([H])C(=C1[H])[N+]([O-])=O)C([H])([H])[H])C1=C([H])N=C2C([H])=C([H])C(Br)=C([H])N12
[H]N1C(=O)C2=C(N=C(S2)N2C3=C(OC([H])([H])C2([H])[H])C([H])=C([H])C(=C3[H])C2=C([H])C([H])=C(OC([H])([H])[H])N=N2)C([H])([H])C1(C([H])([H])[H])C([H])([H])[H]
[H]N([H])C1=C([H])C([H])=C(N=N1)C1=C([H])C2=C(OC([H])([H])C([H])([H])N2C2=NC3=C(S2)C(=O)N([H])C(C([H])([H])[H])(C([H])([H])[H])C3([H])[H])C([H])=C1[H]
[H]C1=C(C2=C(S1)C([H])=C([H])C([H])=C2[H])C([H])([H])[C@]1([H])N(C2=NC3=C(S2)C(=O)C([H])([H])C(C([H])([H])[H])(C([H])([H])[H])C3([H])[H])C([H])([H])C([H])([H])OC1([H])[H]
[H]N1C(=O)C2=C(N=C(S2)N2C3=C(OC([H])([H])C2([H])[H])C([H])=C([H])C(=C3[H])C2=NC([H])=C([H])C([H])=N2)C([H])([H])C1(C([H])([H])[H])C([H])([H])[H]
[H]C1=NC(=C([H])C([H])=C1C1=C([H])C2=C(OC([H])([H])C([H])([H])N2C2=NC3=C(S2)C(=O)C([H])([H])C(C([H])([H])[H])(C([H])([H])[H])C3([H])[H])C([H])=C1[H])C([H])([H])[H]
[H]N1C(=O)C2=C(N=C(S2)N2C3=C(OC([H])([H])C2([H])[H])C([H])=C([H])C(=C3[H])C2=C([H])C([H])=C(N=C2[H])C([H])([H])[H])C([H])([H])C1(C([H])([H])[H])C([H])([H])[H]
[H]C1=NC([H])=C([H])C(=C1[H])C1=C([H])C2=C(OC([H])([H])C([H])([H])N2C2=NC3=C(S2)C(=O)C([H])([H])C(C([H])([H])[H])(C([H])([H])[H])C3([H])[H])C([H])=C1[H]
[H]C1=C([H])C([H])=C(C([H])=N1)C1=C([H])C2=C(OC([H])([H])C([H])([H])N2C2=NC3=C(S2)C(=O)C([H])([H])C(C([H])([H])[H])(C([H])([H])[H])C3([H])[H])C([H])=C1[H]
[H]C1=NC(=C([H])C([H])=C1[H])C1=C([H])C2=C(OC([H])([H])C([H])([H])N2C2=NC3=C(S2)C(=O)C([H])([H])C(C([H])([H])[H])(C([H])([H])[H])C3([H])[H])C([H])=C1[H]
[H]C1=NC2=C(C([H])=C1[H])N(C1=NC3=C(S1)C(=O)C([H])([H])C(C([H])([H])[H])(C([H])([H])[H])C3([H])[H])C([H])([H])C([H])([H])O2
[H]N1C([H])=C(C2=C1N=C([H])C([H])=C2[H])C([H])([H])[C@]1([H])N(C2=NC3=C(S2)C(=O)C([H])([H])C(C([H])([H])[H])(C([H])([H])[H])C3([H])[H])C([H])([H])C([H])([H])OC1([H])[H]
[H]N1C([H])=C(C2=C1C([H])=C([H])C([H])=C2[H])C([H])([H])[C@]1([H])N(C2=NC3=C(S2)C(=O)C([H])([H])C(C([H])([H])[H])(C([H])([H])[H])C3([H])[H])C([H])([H])C([H])([H])OC1([H])[H]
[H]N1C(=O)C2=C(N=C(S2)N2C3=C(OC([H])([H])C2([H])[H])C([H])=C([H])C([H])=C3[H])C([H])([H])C1(C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])C2=C(C([H])=C1[H])N(C1=NC3=C(S1)C(=O)C([H])([H])C(C([H])([H])[H])(C([H])([H])[H])C3([H])[H])C([H])([H])C([H])([H])O2
[H]N1C(=O)C2=C(N=C(S2)N2C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])C([H])([H])C1(C([H])([H])[H])C([H])([H])[H]
[H]N1C(=O)C2=C(N=C(S2)N2C3=C(OC([H])([H])C2([H])[H])C([H])=C([H])C(=C3[H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1(C([H])([H])[H])C([H])([H])[H]
[H]N1C(=O)C2=C(N=C(S2)N2C3=C(OC([H])([H])C2([H])[H])C([H])=C([H])C(=C3[H])C2([H])C([H])([H])C2([H])[H])C([H])([H])C1(C([H])([H])[H])C([H])([H])[H]
[H]N1C(=O)C2=C(N=C(S2)N2C3=C(OC([H])([H])C2([H])[H])C([H])=C([H])C(=C3[H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1(C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C2=C(C([H])=C1[H])N(C1=NC3=C(S1)C(=O)C([H])([H])C(C([H])([H])[H])(C([H])([H])[H])C3([H])[H])C([H])([H])C([H])([H])O2
[H]N1C(=O)C2=C(N=C(S2)N2C3=C(OC([H])([H])C2([H])[H])C([H])=C([H])C(=C3[H])C(=O)C([H])([H])[H])C([H])([H])C1(C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])C2=C(OC([H])([H])C([H])([H])N2C2=NC3=C(S2)C(=O)C([H])([H])C(C([H])([H])[H])(C([H])([H])[H])C3([H])[H])C([H])=C1Br
[H]N1C(=O)C2=C(N=C(S2)N2C3=C(OC([H])([H])C2([H])[H])C([H])=C(C([H])=C3[H])C([H])([H])[H])C([H])([H])C1(C([H])([H])[H])C([H])([H])[H]
[H]N1C(=O)C2=C(N=C(S2)N2C3=C(OC([H])([H])C2([H])[H])C([H])=C(F)C([H])=C3[H])C([H])([H])C1(C([H])([H])[H])C([H])([H])[H]
[H]N([H])C([H])([H])C([H])([H])C([H])([H])N1N=C(C(=C1[H])C1=C([H])C2=C(OC([H])([H])C([H])([H])N2C2=NC3=C(S2)C(=O)N([H])C(C([H])([H])[H])(C([H])([H])[H])C3([H])[H])C([H])=C1[H])C([H])([H])[H]
[H]N1C(=O)C2=C(N=C(S2)N2C3=C(OC([H])([H])C2([H])[H])C([H])=C([H])C(=C3[H])C2=C([H])N(N=C2[H])C([H])([H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1(C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])C2=C(C([H])=C1Br)N(C1=NC3=C(S1)C(=O)C([H])([H])C(C([H])([H])[H])(C([H])([H])[H])C3([H])[H])C([H])([H])C([H])([H])O2
[H]C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C2=C(OC([H])([H])C([H])([H])N2C2=NC3=C(S2)C(=O)C([H])([H])C(C([H])([H])[H])(C([H])([H])[H])C3([H])[H])C([H])=C1[H]
[H]C([H])([H])C1(C([H])([H])[H])C([H])([H])C2=C(SC(=N2)N2C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])C(=O)C1([H])[H]
[H]N1C(=O)C2=C(N=C(S2)N2C3=C(OC([H])([H])C2([H])[H])C([H])=C([H])C(Br)=C3[H])C([H])([H])C1(C([H])([H])[H])C([H])([H])[H]
[H]N1C(=O)C2=C(N=C(S2)N2C3=C(OC([H])([H])C2([H])[H])C([H])=C([H])C(=C3[H])C([H])([H])[H])C([H])([H])C1(C([H])([H])[H])C([H])([H])[H]
[H]N1C(=O)C2=C(N=C(S2)N2C3=C(OC([H])([H])C2([H])[H])C([H])=C(OC([H])([H])[H])C([H])=C3[H])C([H])([H])C1(C([H])([H])[H])C([H])([H])[H]
[H]C1=NN(C([H])=C1C1=C([H])C2=C(OC([H])([H])C([H])([H])N2C2=NC3=C(S2)C(=O)C([H])([H])C(C([H])([H])[H])(C([H])([H])[H])C3([H])[H])C([H])=C1[H])C([H])([H])[H]
[H]N1C(=O)C2=C(N=C(S2)N2C3=C(OC([H])([H])C2([H])[H])C([H])=C([H])C(=C3[H])C2=C([H])N(N=C2[H])C([H])([H])[H])C([H])([H])C1(C([H])([H])[H])C([H])([H])[H]
[H]C1([H])OC([H])([H])C([H])([H])N(C2=NC3=C(S2)C(=O)C([H])([H])C2(C3([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C1([H])[H]
[H]C1([H])OC([H])([H])C([H])([H])N(C2=NC3=C(S2)C(=O)C([H])([H])C([H])([H])C3([H])[H])C1([H])[H]
[H]N1C(=O)C2=C(N=C(S2)N2C3=C(OC([H])([H])C2([H])[H])C([H])=C([H])C(=C3[H])C2=NC([H])=C([H])N2C([H])([H])[H])C([H])([H])C1(C([H])([H])[H])C([H])([H])[H]
[H]N1C([H])=C(N=C1C([H])([H])[H])C1=C([H])C2=C(OC([H])([H])C([H])([H])N2C2=NC3=C(S2)C(=O)N([H])C(C([H])([H])[H])(C([H])([H])[H])C3([H])[H])C([H])=C1[H]
[H]N1N=C([H])C([H])=C1C1=C([H])C2=C(OC([H])([H])C([H])([H])N2C2=NC3=C(S2)C(=O)N([H])C(C([H])([H])[H])(C([H])([H])[H])C3([H])[H])C([H])=C1[H]
[H]N1C(=O)C2=C(N=C(S2)N2C3=C(OC([H])([H])C2([H])[H])C([H])=C([H])C(=C3[H])C2=C([H])N(N=C2[H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1(C([H])([H])[H])C([H])([H])[H]
[H]N1C(=O)C2=C(N=C(S2)N2C3=C(OC([H])([H])C2([H])[H])C([H])=C([H])C(=C3[H])C2=C([H])N(N=C2[H])C([H])([H])C2=C([H])N=C([H])C([H])=C2[H])C([H])([H])C1(C([H])([H])[H])C([H])([H])[H]
[H]N1C(=O)C2=C(N=C(S2)N2C3=C(OC([H])([H])C2([H])[H])C([H])=C([H])C(=C3[H])C2=C([H])N(N=C2C([H])([H])[H])C([H])([H])[H])C([H])([H])C1(C([H])([H])[H])C([H])([H])[H]
[H]N([H])C([H])([H])C([H])([H])N1N=C([H])C(=C1[H])C1=C([H])C2=C(OC([H])([H])C([H])([H])N2C2=NC3=C(S2)C(=O)N([H])C(C([H])([H])[H])(C([H])([H])[H])C3([H])[H])C([H])=C1[H]
[H]N(C1=C([H])C([H])=C(OC([H])([H])[H])N=N1)C1=C([H])C2=C(OC([H])([H])C([H])([H])N2C2=NC3=C(S2)C(=O)N([H])C(C([H])([H])[H])(C([H])([H])[H])C3([H])[H])C([H])=C1[H]
[H]N(C1=C([H])C([H])=C(N=N1)C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C2=C(OC([H])([H])C([H])([H])N2C2=NC3=C(S2)C(=O)N([H])C(C([H])([H])[H])(C([H])([H])[H])C3([H])[H])C([H])=C1[H]
[H]N([H])C1=C(C([H])=NN1C([H])([H])[H])C1=C([H])C2=C(OC([H])([H])C([H])([H])N2C2=NC3=C(S2)C(=O)N([H])C(C([H])([H])[H])(C([H])([H])[H])C3([H])[H])C([H])=C1[H]
[H]N1N=C([H])C(=C1[H])C1=C([H])C2=C(OC([H])([H])C([H])([H])N2C2=NC3=C(S2)C(=O)C([H])([H])C(C([H])([H])[H])(C([H])([H])[H])C3([H])[H])C([H])=C1[H]
[H]N1N=C([H])C(=C1[H])C1=C([H])C2=C(OC([H])([H])C([H])([H])N2C2=NC3=C(S2)C(=O)N([H])C(C([H])([H])[H])(C([H])([H])[H])C3([H])[H])C([H])=C1[H]
[H]N1C([H])=NC([H])=C1C1=C([H])C2=C(OC([H])([H])C([H])([H])N2C2=NC3=C(S2)C(=O)N([H])C(C([H])([H])[H])(C([H])([H])[H])C3([H])[H])C([H])=C1[H]
[H]N1C(=O)C2=C(N=C(S2)N2C3=C(OC([H])([H])C2([H])[H])C([H])=C([H])C(=C3[H])C2=C([H])C([H])=C(N=N2)C([H])([H])[H])C([H])([H])C1(C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])C([H])=C2C(C([H])=C([H])C([H])=C2C([H])([H])[C@]2([H])N(C3=NC4=C(S3)C(=O)C([H])([H])C(C([H])([H])[H])(C([H])([H])[H])C4([H])[H])C([H])([H])C([H])([H])OC2([H])[H])=C1[H]
[H]N1C(=O)C2=C(N=C(S2)N2C3=C(OC([H])([H])C2([H])[H])C([H])=C([H])C(=C3[H])C2=C([H])C([H])=C(N=N2)N2C([H])([H])C([H])([H])N([H])C([H])([H])C2([H])[H])C([H])([H])C1(C([H])([H])[H])C([H])([H])[H]
[H]N1C(=O)C2=C(N=C(S2)N2C3=C(OC([H])([H])C2([H])[H])C([H])=C([H])C(=C3[H])C2=C([H])C([H])=C(N=N2)N2C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C2([H])[H])C([H])([H])C1(C([H])([H])[H])C([H])([H])[H]
[H]N1C(=O)C2=C(N=C(S2)N2C3=C(OC([H])([H])C2([H])[H])C([H])=C([H])C(=C3[H])C2=C([H])C([H])=C(N=N2)N(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1(C([H])([H])[H])C([H])([H])[H]
[H]N(C1=C([H])C([H])=C(N=N1)N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H])C1=C([H])C2=C(OC([H])([H])C([H])([H])N2C2=NC3=C(S2)C(=O)N([H])C(C([H])([H])[H])(C([H])([H])[H])C3([H])[H])C([H])=C1[H]
[H]N(C1=C(C([H])=C(N=N1)C([H])([H])[H])C([H])([H])[H])C1=C([H])C2=C(OC([H])([H])C([H])([H])N2C2=NC3=C(S2)C(=O)N([H])C(C([H])([H])[H])(C([H])([H])[H])C3([H])[H])C([H])=C1[H]
[H]N(C1=C([H])C([H])=C(N=N1)C([H])([H])[H])C1=C([H])C2=C(OC([H])([H])C([H])([H])N2C2=NC3=C(S2)C(=O)N([H])C(C([H])([H])[H])(C([H])([H])[H])C3([H])[H])C([H])=C1[H]
[H]N(C1=C([H])C([H])=C(N=N1)N(C([H])([H])[H])C([H])([H])[H])C1=C([H])C2=C(OC([H])([H])C([H])([H])N2C2=NC3=C(S2)C(=O)N([H])C(C([H])([H])[H])(C([H])([H])[H])C3([H])[H])C([H])=C1[H]
[H]O[C@]([H])(C([H])([H])OC([H])([H])[H])C([H])([H])N1N=C([H])C(=C1[H])C1=C([H])C2=C(OC([H])([H])C([H])([H])N2C2=NC3=C(S2)C(=O)N([H])C(C([H])([H])[H])(C([H])([H])[H])C3([H])[H])C([H])=C1[H]
[H]N(C1=C([H])C([H])=C(N=N1)N1C([H])([H])C([H])([H])N([H])C([H])([H])C1([H])[H])C1=C([H])C2=C(OC([H])([H])C([H])([H])N2C2=NC3=C(S2)C(=O)N([H])C(C([H])([H])[H])(C([H])([H])[H])C3([H])[H])C([H])=C1[H]
[H]N1N=C(C(=C1C([H])([H])[H])C1=C([H])C2=C(OC([H])([H])C([H])([H])N2C2=NC3=C(S2)C(=O)N([H])C(C([H])([H])[H])(C([H])([H])[H])C3([H])[H])C([H])=C1[H])C([H])([H])[H]
[H]OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])N1N=C([H])C(=C1[H])C1=C([H])C2=C(OC([H])([H])C([H])([H])N2C2=NC3=C(S2)C(=O)N([H])C(C([H])([H])[H])(C([H])([H])[H])C3([H])[H])C([H])=C1[H]
[H]OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])N1N=C(C(=C1C([H])([H])[H])C1=C([H])C2=C(OC([H])([H])C([H])([H])N2C2=NC3=C(S2)C(=O)N([H])C(C([H])([H])[H])(C([H])([H])[H])C3([H])[H])C([H])=C1[H])C([H])([H])[H]
[H]N1C(=O)C2=C(N=C(S2)N2C3=C(OC([H])([H])C2([H])[H])C([H])=C([H])C(=C3[H])C2=C([H])N(N=C2[H])C([H])([H])C([H])([H])[H])C([H])([H])C1(C([H])([H])[H])C([H])([H])[H]
[H]N1C(=O)C2=C(N=C(S2)N2C3=C(OC([H])([H])C2([H])[H])C([H])=C([H])C(=C3[H])C2=C(N(N=C2C([H])([H])[H])C([H])([H])C([H])([H])[H])C([H])([H])[H])C([H])([H])C1(C([H])([H])[H])C([H])([H])[H]
[H]N1C(=O)C2=C(N=C(S2)N2C3=C(OC([H])([H])C2([H])[H])C([H])=C([H])C(=C3[H])C2=C(N(N=C2C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])C1(C([H])([H])[H])C([H])([H])[H]
[H]C([H])([H])[C@]1([H])C([H])([H])C2=C(SC(=N2)N2C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])C(=O)C1([H])[H]
[H]N1C([H])=C(C2=C1C([H])=C([H])C([H])=C2[H])C([H])([H])[C@]1([H])N(C2=NC3=C(S2)C(=O)N([H])C([H])([H])C(C([H])([H])[H])(C([H])([H])[H])C3([H])[H])C([H])([H])C([H])([H])OC1([H])[H]
[H]OC1=C([H])C(N([H])C2=NC3=C(C([H])=C([H])C([H])=C3[H])N2C2=NC(=NC([H])=N2)N([H])C([H])([H])C#N)=C([H])C([H])=C1[H]
[H]OC1=C([H])C([H])=C([H])C(N([H])C2=NC3=C([H])C([H])=C([H])C([H])=C3N2C2=NC(=NC(=N2)N([H])[H])C([H])([H])[H])=C1[H]
[H]N([H])C1=NC(=NC(=N1)C([H])([H])[H])N1C(=NC2=C([H])C([H])=C([H])C([H])=C12)N([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC1=C([H])C(N([H])C2=NC3=C([H])C([H])=C([H])C([H])=C3N2C2=NC(=NC(=N2)N([H])[H])C([H])([H])[H])=C([H])C(O[H])=C1[H]
[H]N([H])C(=O)C1=C([H])C([H])=C([H])C(N([H])C2=NC3=C([H])C([H])=C([H])C([H])=C3N2C2=NC(=NC(=N2)N([H])[H])C([H])([H])[H])=C1[H]
[H]N([H])C1=NC(=NC(=N1)C([H])([H])[H])N1C(=NC2=C([H])C([H])=C([H])C([H])=C12)N([H])C1=C([H])C([H])=C(N([H])C(=O)N([H])C([H])([H])[H])C([H])=C1[H]
[H]N([H])C1=NC(=NC(=N1)C([H])([H])[H])N1C(=NC2=C([H])C([H])=C([H])C([H])=C12)N([H])C1=C([H])C([H])=C(N([H])C(=O)C([H])([H])[H])C([H])=C1[H]
[H]N([H])C1=NC(=NC(=N1)C([H])([H])[H])N1C(=NC2=C([H])C([H])=C([H])C([H])=C12)N([H])C1=C([H])C(N([H])C(=O)C([H])([H])[H])=C([H])C([H])=C1[H]
[H]N([H])C1=NC(=NC(=N1)C([H])([H])[H])N1C(=NC2=C([H])C([H])=C([H])C([H])=C12)N([H])C1=C([H])C2=C(C([H])=C([H])N2[H])C([H])=C1[H]
[H]N([H])C1=NC(=NC(=N1)C([H])([H])[H])N1C(=NC2=C([H])C([H])=C([H])C([H])=C12)N([H])C1=C([H])C2=C(C([H])=NN2[H])C([H])=C1[H]
[H]N([H])C1=NC(=NC(=N1)N1C(=NC2=C1C([H])=C([H])C([H])=C2[H])N([H])C1=NN([H])C([H])=C1[H])C([H])([H])[H]
[H]N([H])C1=NC(=NC(=N1)C([H])([H])[H])N1C(=NC2=C([H])C([H])=C([H])C([H])=C12)N([H])C1=NN(C([H])=C1[H])C([H])([H])[H]
[H]N([H])C1=NC(=NC(=N1)C([H])([H])[H])N1C(=NC2=C([H])C([H])=C([H])C([H])=C12)N([H])C1=NN(C([H])=C1[H])C([H])(F)F
[H]N([H])C1=NC(=NC(=N1)C([H])([H])[H])N1C(=NC2=C([H])C([H])=C([H])C([H])=C12)N([H])C1=NOC([H])=C1[H]
[H]N([H])C1=NC(=NC(=N1)C([H])([H])[H])N1C(=NC2=C([H])C([H])=C([H])C([H])=C12)N([H])C1=NN([H])C2=C1C([H])=C([H])C([H])=C2[H]
[H]N([H])C1=NC(=NC(=N1)C([H])([H])[H])N1C(=NC2=C([H])C([H])=C([H])C([H])=C12)N([H])C1=C([H])N([H])N=C1[H]
[H]N([H])C1=NC(=NC(=N1)C([H])([H])[H])N1C(=NC2=C([H])C([H])=C([H])C([H])=C12)N([H])C1=C([H])C([H])=NN1C([H])([H])[H]
[H]N([H])C1=NC(=NC(=N1)C([H])([H])[H])N1C(=NC2=C([H])C([H])=C([H])C([H])=C12)N([H])C1=C([H])C([H])=C(O1)C(=O)N([H])C([H])([H])[H]
[H]N([H])C1=NC(=NC(=N1)C([H])([H])[H])N1C(=NC2=C([H])C([H])=C([H])C([H])=C12)N([H])C1([H])C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]N(C1=NN([H])C([H])=C1[H])C1=NC2=C([H])C([H])=C([H])C([H])=C2N1C1=NC(=NC(=N1)N([H])C([H])([H])[H])C([H])([H])[H]
[H]N(C1=NN([H])C([H])=C1[H])C1=NC2=C([H])C([H])=C([H])C([H])=C2N1C1=NC(=NC(=N1)N([H])C([H])([H])C#N)C([H])([H])[H]
[H]N(C1=NN([H])C([H])=C1[H])C1=NC2=C([H])C([H])=C([H])C([H])=C2N1C1=NC(=NC(=N1)N([H])C([H])([H])C([H])([H])C#N)C([H])([H])[H]
[H]C#CC([H])([H])N([H])C1=NC(=NC(=N1)C([H])([H])[H])N1C(=NC2=C([H])C([H])=C([H])C([H])=C12)N([H])C1=NN([H])C([H])=C1[H]
[H]N([H])C1=NC(=NC(=N1)C([H])([H])[H])N1C(=NC2=C([H])C(F)=C(F)C([H])=C12)N([H])C1=NN([H])C([H])=C1[H]
[H]OC1=C([H])C([H])=C2C([H])=C(C3=NC4=C([H])C([H])=C([H])C([H])=C4S3)C(=O)OC2=C1[H]
[H]N1C(=O)C(=C([H])C2=C([H])C(OC([H])([H])[H])=C([H])C([H])=C12)C1=NOC(=N1)C1=C([H])C([H])=C([H])C(OC([H])([H])[H])=C1[H]
[H]N(C(=O)N([H])C1=C([H])C2=C(O\C(=C(/[H])C3=C(N([H])C4=C(F)C([H])=C(OC([H])([H])[H])C([H])=C34)C3=C(N(N=C3C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C2=O)C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C(=O)N(C([H])([H])[H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H]
[H]N([H])C1=NN2C([H])=C(C([H])=C(F)C2=N1)C1=C([H])N=C([H])C(=C1[H])S(=O)(=O)N([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]OC1=C([H])C([H])=C([H])C(=C1[H])C1=NC(N2C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])=C2OC3=C(C([H])=C([H])C([H])=N3)C2=N1
[H]N(C(=O)N([H])C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC2=C(C([H])=NN2C2([H])C([H])([H])C([H])([H])N(C([H])([H])C3=C([H])C([H])=C([H])N=C3[H])C([H])([H])C2([H])[H])C(=N1)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]N([H])C1=NC([H])=C(C([H])=N1)C1=NC2=C(SC(=C2C([H])([H])[H])C([H])([H])N2C([H])([H])C([H])([H])N(C([H])([H])C2([H])[H])S(=O)(=O)C([H])([H])[H])C(=N1)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]OC([H])([H])C1=C(OC([H])([H])[H])C([H])=C([H])C(=C1[H])C1=C([H])C([H])=C2C(N=C(N=C2N2C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])N2C([H])([H])[C@@]([H])(O[C@]([H])(C([H])([H])[H])C2([H])[H])C([H])([H])[H])=N1
[H]N([H])C1=NC([H])=C(C([H])=N1)C1=NC2=C(SC(=C2[H])C([H])([H])N2C([H])([H])C([H])([H])N(C([H])([H])C2([H])[H])S(=O)(=O)C([H])([H])[H])C(=N1)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]N([H])C1=NC([H])=C(C([H])=C1[H])C1=NC2=C(SC(=C2[H])C([H])([H])N2C([H])([H])C([H])([H])N(C([H])([H])C2([H])[H])S(=O)(=O)C([H])([H])[H])C(=N1)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]N([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC2=C(SC(=C2[H])C([H])([H])N2C([H])([H])C([H])([H])N(C([H])([H])C2([H])[H])S(=O)(=O)C([H])([H])[H])C(=N1)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]OC(C1=C([H])C2=C(S1)C(=NC(=N2)C1=C(N=C(N=C1[H])N([H])[H])C([H])([H])[H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]OC([H])([H])C1=C([H])C(=C([H])C([H])=C1[H])C1=NC2=C(SC(=C2[H])C([H])([H])N2C([H])([H])C([H])([H])N(C([H])([H])C2([H])[H])S(=O)(=O)C([H])([H])[H])C(=N1)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]C1=C(SC2=C1N=C(N=C2N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C1=C([H])C([H])=NC([H])=C1[H])C([H])([H])N1C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])S(=O)(=O)C([H])([H])[H]
[H]C1=C(SC2=C1N=C(N=C2N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C1=C([H])C([H])=C([H])N=C1[H])C([H])([H])N1C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])S(=O)(=O)C([H])([H])[H]
[H]OC1=C([H])C(=C([H])C([H])=C1[H])C1=NC2=C(SC(=C2[H])C([H])([H])N2C([H])([H])C([H])([H])N(C([H])([H])C2([H])[H])S(=O)(=O)C([H])([H])[H])C(=N1)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]N([H])C1=NC(=C(C([H])=N1)C1=NC2=C(SC(=C2[H])C([H])([H])N2C([H])([H])C([H])([H])N(C([H])([H])C2([H])[H])S(=O)(=O)C([H])([H])[H])C(=N1)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C([H])([H])[H]
[H]OC(C1=C([H])C2=C(S1)C(=NC(=N2)C1=C([H])N=C(N=C1[H])N([H])[H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)N([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC(N2C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])=C2N=NN(C2=N1)C([H])([H])C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C(=O)N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N(C(=O)N([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC(=NC(=N1)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C(=O)N1C([H])([H])C([H])([H])C([H])(N(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N(C(=O)N([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC2=C(C([H])=NN2C([H])([H])C(F)(F)F)C(=N1)N1C([H])([H])[C@@]2([H])O[C@]([H])(C([H])([H])C2([H])[H])C1([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N(C(=O)C([H])([H])SC1=NC2=C(C(=O)N1C1=C([H])C([H])=C([H])C([H])=C1OC([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C1=C([H])C([H])=C2N=C([H])C([H])=NC2=C1[H]
[H]N([H])C1=NC([H])=NC2=C1N=C([H])N2C([H])([H])C1=NC2=C([H])C([H])=C([H])C(=C2C(=O)N1C1=C(C([H])=C([H])C([H])=C1[H])C([H])([H])[H])C([H])([H])[H]
[H]N1C([H])=NC2=C1N=C([H])N=C2SC([H])([H])C1=NC2=C([H])C([H])=C([H])C(Cl)=C2C(=O)N1C1=C(OC([H])([H])[H])C([H])=C([H])C([H])=C1[H]
[H]OC1=C([H])C(F)=C([H])C(=C1[H])C1=NN(C2=C1C(=NC([H])=N2)N([H])[H])C([H])([H])C1=NC2=C([H])C([H])=C([H])C(=C2C(=O)N1C1=C(C([H])=C([H])C([H])=C1[H])C([H])([H])[H])C([H])([H])[H]
[H]N([H])C1=NC([H])=NC2=C1C(=NN2C([H])(C([H])([H])[H])C([H])([H])[H])C#CC1=C([H])C([H])=C([H])N=C1[H]
[H]OC1=C(F)C([H])=C(C([H])=C1[H])C1=NN(C2=C1C(=NC([H])=N2)N([H])[H])C([H])([H])C1=NC2=C([H])C([H])=C([H])C(=C2C(=O)N1C1=C(C([H])=C([H])C([H])=C1[H])C([H])([H])[H])C([H])([H])[H]
[H]OC([H])([H])C#CC1=NN(C2=C1C(=NC([H])=N2)N([H])[H])C([H])([H])C1=NC2=C([H])C([H])=C([H])C(=C2C(=O)N1C1=C(C([H])=C([H])C([H])=C1[H])C([H])([H])[H])C([H])([H])[H]
[H]N([H])C1=NC([H])=NC2=C1C(=NN2C([H])([H])C1=C([H])C2=C([H])C([H])=C([H])C([H])=C2N=C1N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H])C1=C([H])C2=C(N=C(S2)N([H])C(=O)C([H])([H])[H])C([H])=C1[H]
[H]N([H])C1=NC2=C(S1)C([H])=C(C([H])=C2[H])C1=NN(C2=C1C(=NC([H])=N2)N([H])[H])C([H])([H])C1=C([H])C2=C([H])C([H])=C([H])C([H])=C2N=C1N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H]
[H]C1=C([H])C2=C(C([H])=C1[H])N(C(=N2)C([H])(F)F)C1=NC(=NC(=N1)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]OC1=C([H])C([H])=C([H])C(=C1[H])C1=NN(C2=NC([H])=NC(N([H])[H])=C12)C([H])([H])C1=NC2=C(C(=O)N1C1=C(C([H])=C([H])C([H])=C1[H])C([H])([H])[H])C(=C([H])C([H])=C2[H])C([H])([H])[H]
[H]OC1=C([H])C(C#CC2=NN(C3=C2C(=NC([H])=N3)N([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])=C([H])C([H])=C1[H]
[H]N(C1=C(N=C2C([H])=C([H])C([H])=C([H])C2=N1)N([H])S(=O)(=O)C1=C([H])C([H])=C(F)C([H])=C1[H])C1=C([H])C(OC([H])([H])[H])=C([H])C(OC([H])([H])[H])=C1[H]
[H]OC1=C([H])C(=C([H])C([H])=C1[H])C1=C([H])C(=NC(=N1)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])N([H])C1=C([H])C2=C(N([H])N=C2[H])C([H])=C1[H]
[H]OC1=C([H])C(=C([H])C([H])=C1[H])C1=C([H])C(=NC(=N1)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])N([H])C1=C([H])C([H])=C(OC([H])([H])[H])N=C1[H]
CN1N=CC2=C1N=C(C=C2OC1=CC=C(C=C1)S(C)(=O)=O)C1=CC=CC2=C1C=NN2
O=C(NC1=CC=NC=C1)NC1=CC=C(C=C1)C1=NC(=NC(=N1)N1CCOCC1)N1C2CCC1COC2
[H]N1C([H])=NC2=C(C([H])=C([H])C(=C2[H])N2C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])C1=O
[H]N([H])C1=NC2=C(S1)C([H])=C([H])C(=C2[H])C1=C([H])C([H])=NC([H])=C1[H]
[H]N([H])C1=NC2=C(S1)C([H])=C(C([H])=C2[H])C1=C([H])C([H])=NC([H])=C1[H]
[H]OC1=C([H])C(=C([H])C([H])=C1[H])C1=C([H])C2=C(N=C(S2)N([H])[H])C([H])=C1[H]
[H]N([H])C1=NON=C1C1=NOC(=N1)C([H])([H])C1=C([H])C([H])=C([H])S1
[H]N([H])C1=C2C([H])=NN(C2=C([H])C([H])=C1[H])C([H])([H])C1=NC2=C([H])C([H])=C([H])C(=C2C(=O)N1C1=C([H])C([H])=C([H])C([H])=C1C([H])([H])[H])C([H])([H])[H]
[H]OC1=C([H])C(=C([H])C(F)=C1[H])C1=NN(C2=C1C(N([H])[H])=C([H])C([H])=C2[H])C([H])([H])C1=NC2=C(C(=O)N1C1=C([H])C([H])=C([H])C([H])=C1C([H])([H])[H])C(=C([H])C([H])=C2[H])C([H])([H])[H]
[H]OC1=C([H])C([H])=C(C([H])=C1F)C1=NN(C2=C1C(N([H])[H])=C([H])C([H])=C2[H])C([H])([H])C1=NC2=C(C(=O)N1C1=C([H])C([H])=C([H])C([H])=C1C([H])([H])[H])C(=C([H])C([H])=C2[H])C([H])([H])[H]
[H]OC1=C([H])C(=C([H])C([H])=C1F)C1=NN(C2=C1C(N([H])[H])=C([H])C([H])=C2[H])C([H])([H])C1=NC2=C(C(=O)N1C1=C([H])C([H])=C([H])C([H])=C1C([H])([H])[H])C(=C([H])C([H])=C2[H])C([H])([H])[H]
[H]N([H])C1=C([H])C([H])=C([H])C2=C1C(=NN2C([H])([H])C1=NC2=C(C(=O)N1C1=C([H])C([H])=C([H])C([H])=C1C([H])([H])[H])C(=C([H])C([H])=C2[H])C([H])([H])[H])C1=C([H])C([H])=C([H])C2=C1C([H])=C([H])N2[H]
[H]OC([H])([H])C#CC1=NN(C2=C1C(N([H])[H])=C([H])C([H])=C2[H])C([H])([H])C1=NC2=C(C(=O)N1C1=C([H])C([H])=C([H])C([H])=C1C([H])([H])[H])C(=C([H])C([H])=C2[H])C([H])([H])[H]
[H]N(C(=O)C1=C([H])N=C([H])C([H])=C1[H])C1=NC2=C(C([H])=C([H])C(OC([H])([H])[H])=C2OC([H])([H])[H])C2=NC([H])([H])C([H])([H])N12
[H]N1C(=O)S\C(=C(\[H])C2=C([H])C3=NC([H])=C([H])N=C3C([H])=C2[H])C1=O
[H]N([H])C1=NC([H])=C(C([H])=N1)C1=C([H])C(=NC(=N1)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])N([H])C1=C([H])C([H])=C(OC([H])([H])[H])N=C1[H]
[H]N([H])C1=NC([H])=C(C([H])=N1)C1=C2C(=NC(=N1)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])N(C([H])([H])C2([H])[H])S(=O)(=O)C([H])([H])[H]
[H]OC(C([H])([H])[H])(C([H])([H])[H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C3N=C(N=C(N4C([H])([H])C([H])([H])OC([H])([H])C4([H])[H])C3=N2)C2=C(F)C([H])=C([H])C3=C2C([H])=C([H])N3[H])C([H])([H])C1([H])[H]
[H]OC(C([H])([H])[H])(C([H])([H])[H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C3N=C(N=C(N4C([H])([H])C([H])([H])OC([H])([H])C4([H])[H])C3=N2)C2=C([H])C([H])=C([H])C3=C2C([H])=C([H])N3[H])C([H])([H])C1([H])[H]
[H]OC(C([H])([H])[H])(C([H])([H])[H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C3N=C(N=C(N4C([H])([H])C([H])([H])OC([H])([H])C4([H])[H])C3=N2)C2=C([H])C([H])=C([H])C3=C2C([H])=NN3[H])C([H])([H])C1([H])[H]
[H]OC(C([H])([H])[H])(C([H])([H])[H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C3N=C(N=C(N4C([H])([H])C([H])([H])OC([H])([H])C4([H])[H])C3=N2)C2=C([H])N=C(N=C2[H])N([H])[H])C([H])([H])C1([H])[H]
[H]N1C([H])=C([H])C2=C1C([H])=C([H])C(F)=C2C1=NC2=C([H])C([H])=C(N=C2C(=N1)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C([H])([H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]OC([H])([H])C1=C([H])C([H])=C2N=C(N=C(N3C([H])([H])C([H])([H])OC([H])([H])C3([H])[H])C2=N1)C1=C(F)C([H])=C([H])C2=C1C([H])=C([H])N2[H]
[H]OC(C([H])([H])[H])(C([H])([H])[H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C2=NC3=C(S2)N=C(N=C3N2C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])C2=C(F)C([H])=C([H])C3=C2C([H])=C([H])N3[H])C([H])([H])C1([H])[H]
[H]OC(C([H])([H])[H])(C([H])([H])[H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C2=NC3=C(N=C(N=C3N3C([H])([H])C([H])([H])OC([H])([H])C3([H])[H])C3=C(F)C([H])=C([H])C4=C3C([H])=C([H])N4[H])N2[H])C([H])([H])C1([H])[H]
[H]OC(C([H])([H])[H])(C([H])([H])[H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C3=C(S2)C(=NC(=N3)C2=C(F)C([H])=C([H])C3=C2C([H])=C([H])N3[H])N2C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]N(C(=O)C([H])([H])[H])C1=NC2=C(S1)C([H])=C(C([H])=C2[H])C1=C([H])N=C(Cl)C(N([H])S(=O)(=O)C2=C([H])C([H])=C(F)C([H])=C2[H])=C1[H]
[H]N([H])C(=O)C1=C(O[C@@]([H])(C2=C(C([H])=C([H])C([H])=C2[H])C(F)(F)F)C([H])([H])[H])C([H])=C(S1)N1C([H])=NC2=C1C([H])=C(C([H])=C2[H])C([H])([H])N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H]
[H]OC1=C([H])C2=C(N([H])C(=C2[H])C2=NN(C3=C2C(=NC([H])=N3)N([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])=C1[H]
[H]N(C(=O)N(C1=NC([H])=NC(N([H])C2=C([H])C([H])=C(C([H])=C2[H])N2C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])[H])C([H])([H])C2([H])[H])=C1[H])C([H])([H])[H])C1=C(Cl)C(OC([H])([H])[H])=C([H])C(OC([H])([H])[H])=C1Cl
[H]N(C(=O)C([H])([H])[H])C1=C([H])N2N=C(C([H])=C([H])C2=N1)C1=C([H])N=C(Cl)C(N([H])S(=O)(=O)C2=C([H])C([H])=C(F)C([H])=C2[H])=C1[H]
[H]N(C(=O)C1=C([H])C([H])=C2C3=C(C([H])=C(S3)C(=O)N(C3=C([H])C([H])=C(C([H])=C3Cl)C(=O)N(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])OC2=C1[H])C([H])([H])[H]
[H]N(C1=C([H])C([H])=C2OC(C(=O)N([H])C2=N1)(C([H])([H])[H])C([H])([H])[H])C1=C(F)C([H])=NC(=N1)N([H])C1=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C(OC([H])([H])[H])=C1[H]
[H]C1=C([H])N(C2=NC(=C([H])C(=O)N12)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1F
[H]C1=C([H])N(C2=NC(=C([H])C(=O)N12)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C(F)=C1[H]
[H]C1=C([H])N(C2=NC(=C([H])C(=O)N12)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]C1=C([H])N(C2=NC(=C([H])C(=O)N12)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C(Cl)=C1[H]
[H]C1=C([H])N(C2=NC(=C([H])C(=O)N12)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]C1=C([H])N(C2=NC(=C([H])C(=O)N12)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1C([H])([H])[H]
[H]C1=C([H])N(C2=NC(=C([H])C(=O)N12)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C(=C1[H])C([H])([H])[H]
[H]C1=C([H])N(C2=NC(=C([H])C(=O)N12)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C(=C1[H])C(F)(F)F
[H]C1=C([H])N(C2=NC(=C([H])C(=O)N12)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C(Cl)C(Cl)=C1[H]
[H]C1=C([H])N(C2=NC(=C([H])C(=O)N12)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C(F)C(Cl)=C1[H]
[H]C1=C([H])N(C2=NC(=C([H])C(=O)N12)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C(Cl)=C1Cl
[H]C1=C([H])N(C2=NC(=C([H])C(=O)N12)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C2=C([H])C([H])=C([H])C([H])=C12
[H]C1=C([H])N(C2=NC(=C([H])C(=O)N12)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C(=C1C([H])([H])[H])C(F)(F)F
[H]C1=C(N(C2=NC(=C([H])C(=O)N12)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C([H])([H])C1=C(Cl)C(Cl)=C([H])C([H])=C1[H])C([H])([H])[H]
[H]C1=C(N(C2=NC(=C([H])C(=O)N12)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C([H])([H])C1=C(C(=C([H])C([H])=C1[H])C(F)(F)F)C([H])([H])[H])C([H])([H])[H]
[H]C1=C(N(C2=NC(=C([H])C(=O)N12)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C([H])([H])C1=C(C(=C([H])C([H])=C1[H])C(F)(F)F)C([H])([H])[H])C([H])([H])C([H])([H])[H]
[H]C1=C([H])C2=C(C([H])=C1[H])N(C1=NC(=C([H])C(=O)N21)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C([H])([H])C1=C(Cl)C(Cl)=C([H])C([H])=C1[H]
[H]C1=C([H])C(=C(Cl)C(Cl)=C1[H])C([H])([H])N1C2=NC(=C([H])C(=O)N2C(=C1C([H])([H])[H])C([H])([H])[H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]C1=C([H])C(=C(C(=C1[H])C(F)(F)F)C([H])([H])[H])C([H])([H])N1C2=NC(=C([H])C(=O)N2C(=C1C([H])([H])[H])C([H])([H])[H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]C1=C([H])C2=C(C([H])=C1[H])N(C1=NC(=C([H])C(=O)N21)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C2=C([H])C([H])=C([H])C([H])=C12
[H]C1=C([H])C2=C(C([H])=C1[H])N(C1=NC(=C([H])C(=O)N21)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C([H])([H])C1=C(C(=C([H])C([H])=C1[H])C(F)(F)F)C([H])([H])[H]
[H]C1=C([H])N(C2=NC(N3C([H])([H])C([H])([H])OC([H])([H])C3([H])[H])=C(F)C(=O)N12)C([H])([H])C1=C([H])C([H])=C([H])C(Cl)=C1Cl
[H]C1=C([H])N(C2=C([H])C(=NC(=O)N12)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C(Cl)=C1Cl
[H]C1=C([H])N(C2=C([H])C(=NC(=O)N12)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C(=C1C([H])([H])[H])C(F)(F)F
[H]C1=C([H])N(C2=NC(=C([H])C(=O)N12)N1C([H])([H])C([H])([H])O[C@@]([H])(C([H])([H])[H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C(Cl)=C1Cl
[H]C1=C([H])N(C2=NC(=C([H])C(=O)N12)N1C([H])([H])C([H])([H])OC(C([H])([H])[H])(C([H])([H])[H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C(Cl)=C1Cl
[H]C1=C([H])N(C2=NC(=C([H])C(=O)N12)N1C([H])([H])C([H])([H])O[C@]([H])(C([H])([H])[H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C(=C1C([H])([H])[H])C(F)(F)F
[H]OC([H])([H])[C@]1([H])OC([H])([H])C([H])([H])N(C2=C([H])C(=O)N3C([H])=C([H])N(C3=N2)C([H])([H])C2=C([H])C([H])=C([H])C(Cl)=C2Cl)C1([H])[H]
[H]C1=C([H])N(C2=NC(=C([H])C(=O)N12)C1=C([H])C([H])([H])OC([H])([H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C(=C1C([H])([H])[H])C(F)(F)F
[H]C1=C([H])N(C2=NC(=C([H])C(=O)N12)C1([H])C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C(=C1C([H])([H])[H])C(F)(F)F
[H]C1=C([H])N(C2=NC(=C([H])C(=O)N12)N1C([H])([H])C([H])([H])SC([H])([H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C(Cl)=C1Cl
[H]N1C(=O)C2=C(C3=C([H])C([H])=C(Cl)C(Cl)=C3N2C([H])([H])[H])[C@@]([H])(C#N)[C@@]11C([H])([H])C([H])([H])N([H])C([H])([H])C1([H])[H]
[H]N(C1=NC([H])=C2N(C(=O)[C@]([H])(N(C2=N1)C1([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C([H])([H])[H])C([H])([H])[H])C1=C(OC([H])([H])[H])C([H])=C(C([H])=C1[H])C(=O)N([H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H]
[H]\C(=N/N(C([H])([H])[H])S(=O)(=O)C1=C(C([H])=C([H])C(=C1[H])[N+]([O-])=O)C([H])([H])[H])C1=C2C([H])=C(C#N)C([H])=C([H])N2N=C1[H]
[H]\C(=N/N(C([H])([H])C([H])([H])[H])S(=O)(=O)C1=C(C([H])=C([H])C(=C1[H])[N+]([O-])=O)C([H])([H])[H])C1=C2C([H])=C(C#N)C([H])=C([H])N2N=C1[H]
[H]\C(=N/N(C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])S(=O)(=O)C1=C(C([H])=C([H])C(=C1[H])[N+]([O-])=O)C([H])([H])[H])C1=C2C([H])=C(C#N)C([H])=C([H])N2N=C1[H]
[H]\C(=N/N(C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H])S(=O)(=O)C1=C(C([H])=C([H])C(=C1[H])[N+]([O-])=O)C([H])([H])[H])C1=C2C([H])=C(C#N)C([H])=C([H])N2N=C1[H]
[H]\C(=N/N(C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H])S(=O)(=O)C1=C(C([H])=C([H])C(=C1[H])[N+]([O-])=O)C([H])([H])[H])C1=C2C([H])=C(C#N)C([H])=C([H])N2N=C1[H]
[H]\C(=N/N(C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])S(=O)(=O)C1=C(C([H])=C([H])C(=C1[H])[N+]([O-])=O)C([H])([H])[H])C1=C2C([H])=C(C#N)C([H])=C([H])N2N=C1[H]
[H]\C(=N/N(C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])S(=O)(=O)C1=C(C([H])=C([H])C(=C1[H])[N+]([O-])=O)C([H])([H])[H])C1=C2C([H])=C(C#N)C([H])=C([H])N2N=C1[H]
[H]OC([H])([H])C([H])([H])N(\N=C(/[H])C1=C2C([H])=C(C#N)C([H])=C([H])N2N=C1[H])S(=O)(=O)C1=C(C([H])=C([H])C(=C1[H])[N+]([O-])=O)C([H])([H])[H]
[H]\C(=N/N(C([H])([H])[H])S(=O)(=O)C1=C(C([H])=C([H])C([H])=C1[H])C([H])([H])[H])C1=C2C([H])=C(C#N)C([H])=C([H])N2N=C1[H]
[H]\C(=N/N(C([H])([H])[H])S(=O)(=O)C1=C(C(=C([H])C([H])=C1[H])[N+]([O-])=O)C([H])([H])[H])C1=C2C([H])=C(C#N)C([H])=C([H])N2N=C1[H]
[H]\C(=N/N(C([H])([H])[H])S(=O)(=O)C1=C(C([H])=C(C([H])=C1[H])[N+]([O-])=O)C([H])([H])[H])C1=C2C([H])=C(C#N)C([H])=C([H])N2N=C1[H]
[H]\C(=N/N(C([H])([H])[H])S(=O)(=O)C1=C(C([H])=C([H])C([H])=C1[N+]([O-])=O)C([H])([H])[H])C1=C2C([H])=C(C#N)C([H])=C([H])N2N=C1[H]
[H]N(C(=O)C([H])([H])[H])C1=C([H])C(=C(C([H])=C1[H])C([H])([H])[H])S(=O)(=O)N(\N=C(/[H])C1=C2C([H])=C(C#N)C([H])=C([H])N2N=C1[H])C([H])([H])[H]
[H]N(C(=O)C(F)(F)F)C1=C([H])C(=C(C([H])=C1[H])C([H])([H])[H])S(=O)(=O)N(\N=C(/[H])C1=C2C([H])=C(C#N)C([H])=C([H])N2N=C1[H])C([H])([H])[H]
[H]N([H])C1=C([H])C(=C(C([H])=C1[H])C([H])([H])[H])S(=O)(=O)N(\N=C(/[H])C1=C2C([H])=C(C#N)C([H])=C([H])N2N=C1[H])C([H])([H])[H]
[H]OC(=O)C1=C([H])C(=C(C([H])=C1[H])C([H])([H])[H])S(=O)(=O)N(\N=C(/[H])C1=C2C([H])=C(C#N)C([H])=C([H])N2N=C1[H])C([H])([H])[H]
[H]\C(=N/N(C([H])([H])[H])S(=O)(=O)C1=C(C([H])=C([H])C(=C1[H])C(=O)OC([H])([H])[H])C([H])([H])[H])C1=C2C([H])=C(C#N)C([H])=C([H])N2N=C1[H]
[H]\C(=N/N(C([H])([H])[H])S(=O)(=O)C1=C(C([H])=C([H])C(C#N)=C1[H])C([H])([H])[H])C1=C2C([H])=C(C#N)C([H])=C([H])N2N=C1[H]
[H]\C(=N/N(C([H])([H])[H])S(=O)(=O)C1=C(C([H])=C([H])C(=C1[H])S(=O)(=O)C([H])([H])[H])C([H])([H])[H])C1=C2C([H])=C(C#N)C([H])=C([H])N2N=C1[H]
[H]\C(=N/N(C([H])([H])[H])S(=O)(=O)C1=C(C([H])=C([H])C(=C1[H])C(F)(F)F)C([H])([H])[H])C1=C2C([H])=C(C#N)C([H])=C([H])N2N=C1[H]
[H]\C(=N/N(C([H])([H])[H])S(=O)(=O)C1=C(C([H])=C([H])C(=C1[H])C([H])([H])[H])C([H])([H])[H])C1=C2C([H])=C(C#N)C([H])=C([H])N2N=C1[H]
[H]\C(=N/N(C([H])([H])[H])S(=O)(=O)C1=C(C([H])=C([H])C(F)=C1[H])C([H])([H])[H])C1=C2C([H])=C(C#N)C([H])=C([H])N2N=C1[H]
[H]\C(=N/N(C([H])([H])[H])S(=O)(=O)C1=C(C([H])=C([H])C(Cl)=C1[H])C([H])([H])[H])C1=C2C([H])=C(C#N)C([H])=C([H])N2N=C1[H]
[H]\C(=N/N(C([H])([H])[H])S(=O)(=O)C1=C(C([H])=C([H])C(Br)=C1[H])C([H])([H])[H])C1=C2C([H])=C(C#N)C([H])=C([H])N2N=C1[H]
[H]\C(=N/N(C([H])([H])[H])S(=O)(=O)C1=C([H])C(=C([H])C([H])=C1[H])[N+]([O-])=O)C1=C2C([H])=C(C#N)C([H])=C([H])N2N=C1[H]
[H]\C(=N/N(C([H])([H])[H])S(=O)(=O)C1=C(C([H])=C([H])C(=C1[H])[N+]([O-])=O)C([H])([H])C([H])([H])[H])C1=C2C([H])=C(C#N)C([H])=C([H])N2N=C1[H]
[H]\C(=N/N(C([H])([H])[H])S(=O)(=O)C1=C(C([H])=C([H])C(=C1[H])[N+]([O-])=O)C([H])(C([H])([H])[H])C([H])([H])[H])C1=C2C([H])=C(C#N)C([H])=C([H])N2N=C1[H]
[H]\C(=N/N(C([H])([H])[H])S(=O)(=O)C1=C(F)C([H])=C([H])C(=C1[H])[N+]([O-])=O)C1=C2C([H])=C(C#N)C([H])=C([H])N2N=C1[H]
[H]\C(=N/N(C([H])([H])[H])S(=O)(=O)C1=C(Cl)C([H])=C([H])C(=C1[H])[N+]([O-])=O)C1=C2C([H])=C(C#N)C([H])=C([H])N2N=C1[H]
[H]\C(=N/N(C([H])([H])[H])S(=O)(=O)C1=C(OC([H])([H])[H])C([H])=C([H])C(=C1[H])[N+]([O-])=O)C1=C2C([H])=C(C#N)C([H])=C([H])N2N=C1[H]
[H]\C(=N/N(C([H])([H])[H])S(=O)(=O)C1=C(C([H])=C([H])C(=C1[H])[N+]([O-])=O)N(C([H])([H])[H])C([H])([H])[H])C1=C2C([H])=C(C#N)C([H])=C([H])N2N=C1[H]
[H]\C(=N/N(C(=O)C1=C(C([H])=C([H])C(=C1[H])[N+]([O-])=O)C([H])([H])[H])C([H])([H])[H])C1=C2C([H])=C(C#N)C([H])=C([H])N2N=C1[H]
[H]\C(=N/N(C(=O)C1=C([H])C([H])=C([H])C(=C1[H])[N+]([O-])=O)C([H])([H])[H])C1=C2C([H])=C(C#N)C([H])=C([H])N2N=C1[H]
[H]\C(=N/N(C([H])([H])[H])C([H])([H])C1=C(C([H])=C([H])C(=C1[H])[N+]([O-])=O)C([H])([H])[H])C1=C2C([H])=C(C#N)C([H])=C([H])N2N=C1[H]
[H]N(C1=C([H])C(=C([H])N=C1Cl)C1=C([H])C([H])=C2N=C([H])C([H])=C(N3C([H])([H])C([H])([H])N(C([H])([H])C4=C([H])C([H])=NC([H])=C4[H])C([H])([H])C3([H])[H])C2=C1[H])S(=O)(=O)C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]N(C1=C([H])C(=C([H])N=C1Cl)C1=C([H])C([H])=C2N=C([H])C([H])=C(C3=C([H])N=C([H])C([H])=C3[H])C2=C1[H])S(=O)(=O)C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]N(C1=C([H])C(=C([H])N=C1Cl)C1=C([H])C([H])=C2N=C([H])C([H])=C(C3=C([H])C([H])=NC([H])=C3[H])C2=C1[H])S(=O)(=O)C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]N(C1=C([H])C(=C([H])N=C1Cl)C1=C([H])C([H])=C2N=C([H])C(=NC2=C1[H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])S(=O)(=O)C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]N(C1=NC2=C([H])C(=C([H])C([H])=C2N=C1[H])C1=C([H])N=C(Cl)C(N([H])S(=O)(=O)C2=C([H])C([H])=C(F)C([H])=C2[H])=C1[H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]N(C1=C([H])C(=C([H])N=C1Cl)C1=C([H])C([H])=C2N=C([H])C(=NC2=C1[H])N1C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])S(=O)(=O)C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]N(C1=C([H])C(=C([H])N=C1Cl)C1=C([H])C2=C(C([H])=C([H])N=C2C([H])=C1[H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])S(=O)(=O)C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]OC([H])([H])C(=O)N1C([H])([H])C([H])([H])N(C([H])([H])C2=C(C3=C(S2)C(=NC(=N3)C2=C([H])N=C(N=C2[H])N([H])[H])N2C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N([H])C1=NC([H])=C(C([H])=N1)C1=NC2=C(SC(=C2C([H])([H])[H])C([H])([H])N2C([H])([H])C([H])([H])N(C(=O)C([H])([H])N([H])[H])C([H])([H])C2([H])[H])C(=N1)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]N([H])C1=NC([H])=C(C([H])=N1)C1=NC2=C(SC(=C2C([H])([H])[H])C([H])([H])N2C([H])([H])C([H])([H])N(C(=O)[C@@]([H])(N([H])[H])C([H])([H])[H])C([H])([H])C2([H])[H])C(=N1)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]N([H])C1=NC([H])=C(C([H])=N1)C1=NC2=C(SC(=C2C([H])([H])[H])C([H])([H])N2C([H])([H])C([H])([H])N(C(=O)C(N([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C2([H])[H])C(=N1)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]O[C@]([H])(C(=O)N1C([H])([H])C([H])([H])N(C([H])([H])C2=C(C3=C(S2)C(=NC(=N3)C2=C([H])N=C(N=C2[H])N([H])[H])N2C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H])C([H])([H])[H]
[H]OC(C(=O)N1C([H])([H])C([H])([H])N(C([H])([H])C2=C(C3=C(S2)C(=NC(=N3)C2=C([H])N=C(N=C2[H])N([H])[H])N2C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]OC1=C([H])C([H])=C([H])C2=C1N=C(N2C1=NC(=NC(=N1)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C([H])(F)F
[H]C1=C([H])C2=C(N=C(N2C2=NC(=NC(=N2)N2C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])N2C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])C([H])(F)F)C(OC([H])(F)F)=C1[H]
[H]OC1=C2N=C(N(C2=C([H])C([H])=C1OC([H])([H])[H])C1=NC(=NC(=N1)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C([H])(F)F
[H]N([H])C1=C([H])C(OC([H])([H])[H])=C2N=C(N(C2=C1[H])C1=NC(=NC(=N1)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C([H])(F)F
[H]\C(=N/N(C([H])([H])[H])S(=O)(=O)C1=C(C([H])=C([H])C(=C1[H])[N+]([O-])=O)C([H])([H])[H])C1=C2C([H])=C([H])C([H])=C([H])N2N=C1[H]
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[H]N([H])C1=NC(=NC(=N1)C([H])([H])[H])C1=C([H])N=C([H])N=C1N([H])C1=C([H])C([H])=C(OC([H])([H])[H])N=C1[H]
[H]N([H])C1=NC(=NC(=N1)C1=NC([H])=C([H])C([H])=C1N([H])C1=C([H])C([H])=C(OC([H])([H])[H])N=C1[H])C([H])([H])[H]
[H]N([H])C1=NC(=NC(=N1)C([H])([H])[H])C1=C(N([H])C2=C([H])C([H])=C(OC([H])([H])[H])N=C2[H])C([H])=NC([H])=C1[H]
[H]N([H])C1=NC(=NC(=N1)C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1N([H])C1=C([H])C([H])=C(OC([H])([H])[H])N=C1[H]
[H]OC1=C([H])C([H])=C([H])C(N([H])C2=NC([H])=C([H])C([H])=C2C2=NC(=NC(=C2[H])C([H])([H])[H])N([H])[H])=C1[H]
[H]N(C1=NC([H])=C([H])C([H])=C1C1=C2C([H])=NN([H])C2=NC(=N1)C([H])([H])[H])C1=C([H])C([H])=C([H])C2=C1C([H])=NN2[H]
[H]N(C1=NC([H])=C([H])C([H])=C1C1=C2N=C([H])N([H])C2=NC([H])=N1)C1=C([H])C([H])=C(OC([H])([H])[H])N=C1[H]
[H]N(C1=NC([H])=C([H])C([H])=C1C1=C2N=C([H])N([H])C2=NC(=N1)C([H])([H])[H])C1=C([H])C([H])=C(OC([H])([H])[H])N=C1[H]
[H]N(C1=NC([H])=C([H])C([H])=C1C1=C2N=C([H])N([H])C2=NC(=N1)C([H])([H])[H])C1=C([H])C([H])=C([H])C2=C1C([H])=C([H])N2[H]
[H]N(C1=NC([H])=C([H])C([H])=C1C1=C2N=C([H])N([H])C2=NC(=N1)C([H])([H])[H])C1=C([H])C([H])=C([H])C2=C1C([H])=NN2[H]
[H]N([H])C1=C(F)C(=NC(=N1)C([H])([H])[H])C1=C([H])C([H])=C([H])N=C1N([H])C1=C([H])C([H])=C([H])C2=C1C([H])=NN2[H]
[H]N([H])C1=C([H])C(=NC(=N1)C([H])([H])[H])C1=C([H])C([H])=C([H])N=C1N([H])C1=C([H])C([H])=C([H])C2=C1C([H])=NN2[H]
[H]OC1=C([H])C([H])=C([H])C(N([H])C2=NC([H])=C([H])C([H])=C2C2=NC(=NC(N([H])[H])=C2[H])C([H])([H])[H])=C1[H]
[H]N([H])C1=NC(=NC(=N1)C([H])([H])[H])C1=C([H])C([H])=C([H])N=C1N([H])C1=C([H])C([H])=C(OC([H])([H])[H])N=C1[H]
[H]N([H])C1=NC(=NC(=N1)C1=C([H])C([H])=C([H])N=C1N([H])C1=C([H])C([H])=C([H])C2=C1C([H])=C([H])N2[H])C([H])([H])[H]
[H]N([H])C1=NC(=NC(=N1)C1=C([H])C([H])=C([H])N=C1N([H])C1=C([H])C([H])=C([H])C2=C1C([H])=NN2[H])C([H])([H])[H]
[H]OC1=C([H])C([H])=C([H])C(N([H])C2=NC([H])=C([H])C([H])=C2C2=NC(=NC(=N2)C([H])([H])[H])N([H])[H])=C1[H]
[H]OC1=C([H])C(N([H])C2=NC3=C(C([H])=C([H])C([H])=C3[H])N2C2=NC([H])=NC(=N2)C([H])([H])[H])=C([H])C([H])=C1[H]
[H]OC1=C([H])C([H])=C([H])C(N([H])C2=NC3=C([H])C([H])=C([H])C([H])=C3N2C2=NC(=NC(=N2)N([H])C([H])([H])C#N)C([H])([H])[H])=C1[H]
[H]N(C1=NC(=C([H])C(=O)N1[H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C([H])([H])C1=C2C([H])=C([H])C([H])=C([H])C2=C([H])C([H])=C1[H]
[H]N(C(=O)C([H])([H])C1=NC(=C([H])C(=O)N1[H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C1=C([H])C([H])=C([H])C([H])=C1F
[H]N(C(=O)C([H])([H])C1=NC(=C([H])C(=O)N1[H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C1=C([H])C([H])=C([H])C(F)=C1[H]
[H]N(C(=O)C([H])([H])C1=NC(=C([H])C(=O)N1[H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]N(C(=O)C([H])([H])C1=NC(=C([H])C(=O)N1[H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C1=C([H])C([H])=C([H])C([H])=C1C([H])([H])[H]
[H]N(C(=O)C([H])([H])C1=NC(=C([H])C(=O)N1[H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C1=C([H])C([H])=C([H])C(=C1[H])C([H])([H])[H]
[H]N(C(=O)C([H])([H])C1=NC(=C([H])C(=O)N1[H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]N(C(=O)C([H])([H])C1=NC(=C([H])C(=O)N1[H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C1=C([H])C([H])=C([H])C(Cl)=C1[H]
[H]N(C(=O)C([H])([H])C1=NC(=C([H])C(=O)N1[H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C1=C([H])C([H])=C([H])C(OC([H])([H])[H])=C1[H]
[H]N(C(=O)C([H])([H])C1=NC(=C([H])C(=O)N1[H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C1=C([H])C([H])=C([H])C(Br)=C1[H]
[H]N(C(=O)C([H])([H])C1=NC(=C([H])C(=O)N1[H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C1=C([H])C([H])=C(F)C(F)=C1[H]
[H]N(C(=O)C([H])([H])C1=NC(=C([H])C(=O)N1[H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C1=C([H])C([H])=C(F)C(=C1[H])C([H])([H])[H]
[H]N(C(=O)C([H])([H])C1=NC(=C([H])C(=O)N1[H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C1=C([H])C([H])=C(F)C(Cl)=C1[H]
[H]N(C(=O)C([H])([H])C1=NC(=C([H])C(=O)N1[H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C1=C([H])C([H])=C(F)C(OC([H])([H])[H])=C1[H]
[H]N(C(=O)C([H])([H])C1=NC(=C([H])C(=O)N1[H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C1=C([H])C([H])=C(F)C(Br)=C1[H]
[H]N(C(=O)C([H])([H])C1=NC(=C([H])C(=O)N1[H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C1=C([H])C([H])=C(F)C(=C1[H])C(=O)OC([H])([H])[H]
[H]N(C(=O)C([H])([H])C1=NC(=C([H])C(=O)N1[H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C1=C([H])C([H])=C(F)C(=C1[H])[N+]([O-])=O
[H]N(C(=O)C([H])([H])C1=NC(=C([H])C(=O)N1C([H])([H])[H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)C([H])([H])C1=NC(=C([H])C(=O)N1C([H])([H])[H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]N(C(=O)C([H])([H])C1=NC(=C([H])C(=O)N1C([H])([H])[H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C1=C([H])C([H])=C(F)C(F)=C1[H]
[H]N(C(=O)C([H])([H])C1=NC(=C([H])C(=O)N1C([H])([H])[H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C1=C([H])C([H])=C(F)C(Br)=C1[H]
[H]N(C(=O)C([H])([H])C1=NC(=C([H])C(=O)N1C([H])([H])[H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C1=C([H])C([H])=C(F)C(OC([H])([H])[H])=C1[H]
[H]N(C(=O)C([H])([H])C1=NC(=C([H])C(=O)N1C([H])([H])[H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C1=C([H])C([H])=C(F)C(Cl)=C1[H]
[H]C1=C(SC2=C1N=C(N=C2N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])N1C(=NC2=C1C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])[H])C([H])([H])N1C([H])([H])C([H])([H])N(C([H])([H])C1(C([H])([H])[H])C([H])([H])[H])C1([H])C([H])([H])OC1([H])[H]
[H]OC(C([H])([H])[H])(C([H])([H])[H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C3=C(S2)C(=NC(=N3)N2C(=NC3=C2C([H])=C([H])C([H])=C3[H])C([H])([H])C([H])([H])[H])N2C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]C1=C(SC2=C1N=C(N=C2N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])N1C(=NC2=C1C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])[H])C([H])([H])N1C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])S(=O)(=O)C([H])([H])[H]
[H]N([H])C(=O)C(N1C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C3=C(S2)C(=NC(=N3)N2C(=NC3=C2C([H])=C([H])C([H])=C3[H])C([H])([H])[H])N2C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])C([H])([H])C1([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]C1=C(SC2=C1N=C(N=C2N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])N1C(=NC2=C1C([H])=C([H])C([H])=C2[H])C([H])([H])[H])C([H])([H])N1C([H])([H])C([H])([H])C([H])(N(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]C1=NC2=C(C([H])=C([H])C([H])=C2[H])N1C1=NC2=C(SC(=C2[H])C([H])([H])N2C([H])([H])C([H])([H])C([H])(N(C([H])([H])[H])C([H])([H])[H])C([H])([H])C2([H])[H])C(=N1)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]C1=C([H])C2=C(C([H])=C([H])C([H])=C2[H])N1C1=NC2=C(SC(=C2[H])C([H])([H])N2C([H])([H])C([H])([H])C([H])(N(C([H])([H])[H])C([H])([H])[H])C([H])([H])C2([H])[H])C(=N1)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]N1C([H])=C(C2=C1C([H])=C([H])C([H])=C2[H])C1=NC2=C(SC(=C2[H])C([H])([H])N2C([H])([H])C([H])([H])C([H])(N(C([H])([H])[H])C([H])([H])[H])C([H])([H])C2([H])[H])C(=N1)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]C1=NN(C2=C1C([H])=C([H])C([H])=C2[H])C1=NC2=C(SC(=C2[H])C([H])([H])N2C([H])([H])C([H])([H])C([H])(N(C([H])([H])[H])C([H])([H])[H])C([H])([H])C2([H])[H])C(=N1)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]N1N=C(C2=C1C([H])=C([H])C([H])=C2[H])C1=NC2=C(SC(=C2[H])C([H])([H])N2C([H])([H])C([H])([H])C([H])(N(C([H])([H])[H])C([H])([H])[H])C([H])([H])C2([H])[H])C(=N1)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]C1=C(SC2=C1N=C(N=C2N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C1=C(SC2=C1C([H])=C([H])C([H])=C2[H])C([H])([H])[H])C([H])([H])N1C([H])([H])C([H])([H])C([H])(N(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]C1=C(SC2=C1N=C(N=C2N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C1=C(N=C([H])C2=C([H])C([H])=C([H])C([H])=C12)C([H])([H])[H])C([H])([H])N1C([H])([H])C([H])([H])C([H])(N(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]C1=C([H])N2C(=N1)C([H])=C([H])C([H])=C2C1=NC2=C(SC(=C2[H])C([H])([H])N2C([H])([H])C([H])([H])C([H])(N(C([H])([H])[H])C([H])([H])[H])C([H])([H])C2([H])[H])C(=N1)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]C1=C(SC2=C1N=C(N=C2N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C1=C([H])C([H])=C([H])C(=C1[H])C([H])([H])[H])C([H])([H])N1C([H])([H])C([H])([H])C([H])(N(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N1C(=O)C([H])([H])C2=C1C([H])=C([H])C([H])=C2C1=NC2=C(SC(=C2[H])C([H])([H])N2C([H])([H])C([H])([H])C([H])(N(C([H])([H])[H])C([H])([H])[H])C([H])([H])C2([H])[H])C(=N1)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]N1C([H])=C([H])C2=C1C([H])=C([H])C(F)=C2C1=NC2=C(SC(=C2[H])C([H])([H])N2C([H])([H])C([H])([H])C([H])(N(C([H])([H])[H])C([H])([H])[H])C([H])([H])C2([H])[H])C(=N1)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]N([H])C(=O)C(N1C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C3=C(S2)C(=NC(=N3)C2=C([H])C([H])=NC3=C2C([H])=C([H])N3[H])N2C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])C([H])([H])C1([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]N([H])C(=O)C(N1C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C3=C(S2)C(=NC(=N3)C2=C([H])N=C([H])C3=C2C([H])=C([H])N3[H])N2C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])C([H])([H])C1([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]N([H])C(=O)C(N1C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C3=C(S2)C(=NC(=N3)C2=NC([H])=C([H])C3=C2C([H])=C([H])N3[H])N2C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])C([H])([H])C1([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]N([H])C(=O)C(N1C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C3=C(S2)C(=NC(=N3)C2=C([H])C([H])=C([H])C3=C2C([H])=C([H])N3C([H])([H])[H])N2C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])C([H])([H])C1([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]N([H])C(=O)C(N1C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C3=C(S2)C(=NC(=N3)C2=C([H])C([H])=C([H])C3=C2C([H])=C(N3[H])C([H])([H])[H])N2C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])C([H])([H])C1([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]N([H])C(=O)C(N1C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C3=C(S2)C(=NC(=N3)C2=C(F)C([H])=C(F)C3=C2C([H])=C([H])N3[H])N2C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])C([H])([H])C1([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]N([H])C(=O)C(N1C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C3=C(S2)C(=NC(=N3)C2=C([H])C(C#N)=C([H])C3=C2C([H])=C([H])N3[H])N2C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])C([H])([H])C1([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]N([H])C(=O)C(N1C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C3=C(S2)C(=NC(=N3)C2=C([H])C(F)=C([H])C3=C2C([H])=C([H])N3[H])N2C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])C([H])([H])C1([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]N1C([H])=C([H])C2=C1C([H])=C([H])C(F)=C2C1=NC2=C(SC(=C2[H])C([H])([H])N2C([H])([H])C([H])([H])N3C([H])([H])C([H])([H])OC([H])([H])[C@@]3([H])C2([H])[H])C(=N1)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]N([H])C(=O)C(N1C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C3=C(S2)C(=NC(=N3)C2=C(F)C([H])=C([H])C3=C2C([H])=C([H])N3[H])N2C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])C([H])([H])C1([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]N([H])C(=O)C(N1C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C3=C(S2)C(=NC(=N3)C2=C([H])C([H])=C([H])C3=C2C([H])=NN3[H])N2C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])C([H])([H])C1([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]N1C([H])=C([H])C2=C1C([H])=C([H])C([H])=C2C1=NC2=C(SC(=C2[H])C([H])([H])N2C([H])([H])C([H])([H])N(C([H])([H])C2([H])[H])S(=O)(=O)C([H])([H])[H])C(=N1)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]N([H])C(=O)C(N1C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C3=C(S2)C(=NC(=N3)C2=C([H])C([H])=C([H])C3=C2C([H])=C([H])N3[H])N2C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])C([H])([H])C1([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]OC([H])([H])C([H])([H])N(C1=C([H])C(=NC(=O)N1[H])N1C([H])([H])C([H])([H])O[C@@]([H])(C([H])([H])[H])C1([H])[H])C([H])([H])C1=C2C([H])=C([H])C([H])=C([H])C2=C([H])C([H])=C1[H]
[H]C1=C([H])C([H])=C([H])C(=N1)C1=C(C(N2C3=C(C([H])=C([H])C(=C3[H])N3C([H])([H])C([H])([H])OC([H])([H])C3([H])[H])C3(C([H])([H])S(=O)(=O)C3([H])[H])C2([H])[H])=C2C([H])=C([H])C(F)=C([H])C2=N1)C([H])([H])[H]
[H]C1=C([H])C([H])=C([H])C(=N1)C1=C(C(N2C3=C(N=C([H])C(=C3[H])N3C([H])([H])C([H])([H])OC([H])([H])C3([H])[H])C(C([H])([H])[H])(C([H])([H])[H])C2([H])[H])=C2C([H])=C([H])C(F)=C([H])C2=N1)C([H])([H])[H]
[H]N([H])C1=NC(=C([H])C(=N1)C1=C([H])C2=C(C([H])=C1[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])N2C1=C2C([H])=C([H])C(F)=C([H])C2=NC(C2=NC([H])=C([H])C([H])=C2[H])=C1C([H])([H])[H])C([H])([H])[H]
[H]N([H])C1=NC([H])=C([H])C(=N1)C1=C([H])C2=C(N=C1[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])N2C1=C2C([H])=C([H])C(F)=C([H])C2=NC(C2=NC([H])=C([H])C([H])=C2[H])=C1C([H])([H])[H]
[H]C1=NC([H])=C([H])C(=C1[H])C1=C([H])C2=C(C([H])=C1[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])N2C1=C2C([H])=C([H])C(F)=C([H])C2=NC(C2=NC([H])=C([H])C([H])=C2[H])=C1C([H])([H])[H]
[H]OC([H])([H])C1(C2=C(C([H])=C(C([H])=C2[H])N2C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])N(C2=C3C([H])=C([H])C(F)=C([H])C3=NC(C3=NC([H])=C([H])C([H])=C3[H])=C2C([H])([H])[H])C1([H])[H])C([H])([H])O[H]
[H]C1=C([H])C([H])=C([H])C(=N1)C1=C(C(N2C3=C(N=C([H])C(=C3[H])N3C([H])([H])C([H])([H])OC([H])([H])C3([H])[H])C3(C2([H])[H])C([H])([H])C([H])([H])OC([H])([H])C3([H])[H])=C2C([H])=C([H])C(F)=C([H])C2=N1)C([H])([H])[H]
[H]N([H])C1=NC([H])=C([H])C(=N1)C1=C([H])C2=C(C([H])=C1[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])N2C1=C2C([H])=C([H])C(F)=C([H])C2=NC(C2=NC([H])=C([H])C([H])=C2[H])=C1C([H])([H])[H]
[H]C1=C([H])C(=C([H])C2=C1C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])N2C1=C2C([H])=C(Cl)C([H])=C([H])C2=NC(=C1C([H])([H])[H])C([H])([H])[H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]C1=C([H])C2=NC(=C(C(N3C4=C(C([H])=C([H])C(=C4[H])N4C([H])([H])C([H])([H])OC([H])([H])C4([H])[H])C(C([H])([H])[H])(C([H])([H])[H])C3([H])[H])=C2C([H])=C1[H])C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])C2=NC(C3=C([H])C([H])=C([H])C([H])=C3F)=C(C(N3C4=C(C([H])=C([H])C(=C4[H])N4C([H])([H])C([H])([H])OC([H])([H])C4([H])[H])C(C([H])([H])[H])(C([H])([H])[H])C3([H])[H])=C2C([H])=C1[H])C([H])([H])[H]
[H]C1=C([H])C2=NC(=C(C(N3C4=C(C([H])=C([H])C(=C4[H])N4C([H])([H])C([H])([H])OC([H])([H])C4([H])[H])C4(C3([H])[H])C([H])([H])C([H])([H])OC([H])([H])C4([H])[H])=C2C([H])=C1[H])C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])C([H])=C([H])C(=N1)C1=C(C(N2C3=C(C([H])=C([H])C(=C3[H])N3C([H])([H])C([H])([H])OC([H])([H])C3([H])[H])C(C([H])([H])[H])(C([H])([H])[H])C2([H])[H])=C2C(F)=C([H])C([H])=C([H])C2=N1)C([H])([H])[H]
[H]C1=C([H])C([H])=C([H])C(=N1)C1=C(C(N2C3=C(C([H])=C([H])C(=C3[H])N3C([H])([H])C([H])([H])OC([H])([H])C3([H])[H])C3(C2([H])[H])C([H])([H])C([H])([H])OC([H])([H])C3([H])[H])=C2C([H])=C([H])C(F)=C([H])C2=N1)C([H])([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C1=C(C(N2C3=C(C([H])=C([H])C(=C3[H])N3C([H])([H])C([H])([H])OC([H])([H])C3([H])[H])C(C([H])([H])[H])(C([H])([H])[H])C2([H])[H])=C2C([H])=C([H])C([H])=C([H])C2=N1)C([H])([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C1=C(C(N2C3=C(C([H])=C([H])C(=C3[H])N3C([H])([H])C([H])([H])OC([H])([H])C3([H])[H])C3(C2([H])[H])C([H])([H])C([H])([H])OC([H])([H])C3([H])[H])=C2C([H])=C([H])C([H])=C([H])C2=N1)C([H])([H])[H]
[H]C1=C([H])C([H])=C([H])C(=N1)C1=C(C(N2C3=C(C([H])=C([H])C(=C3[H])N3C([H])([H])C([H])([H])OC([H])([H])C3([H])[H])C(C([H])([H])[H])(C([H])([H])[H])C2([H])[H])=C2C([H])=C([H])C(F)=C([H])C2=N1)C([H])([H])[H]
[H]C1=NC([H])=C(C([H])=C1[H])C1=C(C(N2C3=C(C([H])=C([H])C(=C3[H])N3C([H])([H])C([H])([H])OC([H])([H])C3([H])[H])C(C([H])([H])[H])(C([H])([H])[H])C2([H])[H])=C2C([H])=C([H])C(F)=C([H])C2=N1)C([H])([H])[H]
[H]OC(C([H])([H])[H])(C([H])([H])[H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C2=NC3=C(N=C(N=C3N3C([H])([H])C([H])([H])OC([H])([H])C3([H])[H])N3C4=C(N=C3[C@]([H])(OC([H])([H])[H])C([H])([H])[H])C([H])=C([H])C([H])=C4[H])N2C([H])([H])[H])C([H])([H])C1([H])[H]
[H]OC(C([H])([H])[H])(C([H])([H])[H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C2=NC3=C(N=C(N=C3N3C([H])([H])C([H])([H])OC([H])([H])C3([H])[H])N3C4=C(N=C3C([H])([H])C([H])([H])[H])C([H])=C([H])C([H])=C4[H])N2C([H])([H])[H])C([H])([H])C1([H])[H]
[H]C1=C([H])C2=C(C([H])=C1[H])N(C(=N2)C([H])([H])C([H])([H])[H])C1=NC2=C(N=C(N2C([H])([H])[H])C([H])([H])N2C([H])([H])C([H])([H])N(C([H])([H])C2([H])[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C(=N1)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]OC(C([H])([H])[H])(C([H])([H])[H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C2=NC3=C(S2)N=C(N=C3N2C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])N2C(=NC3=C2C([H])=C([H])C([H])=C3[H])C([H])([H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]OC(C([H])([H])[H])(C([H])([H])[H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C2=NC3=C(N=C(N=C3N3C([H])([H])C([H])([H])OC([H])([H])C3([H])[H])N3C(=NC4=C3C([H])=C([H])C([H])=C4[H])N3C([H])([H])C([H])([H])OC([H])([H])C3([H])[H])N2C([H])([H])[H])C([H])([H])C1([H])[H]
[H]OC(C([H])([H])[H])(C([H])([H])[H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C2=NC3=C(N=C(N=C3N3C([H])([H])C([H])([H])OC([H])([H])C3([H])[H])N3C4=C(N=C3C3([H])C([H])([H])C3([H])[H])C([H])=C([H])C([H])=C4[H])N2C([H])([H])[H])C([H])([H])C1([H])[H]
[H]O[C@@]([H])(C1=NC2=C(C([H])=C([H])C([H])=C2[H])N1C1=NC2=C(N=C(N2C([H])([H])[H])C([H])([H])N2C([H])([H])C([H])([H])C([H])(C([H])([H])C2([H])[H])C(O[H])(C([H])([H])[H])C([H])([H])[H])C(=N1)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C([H])([H])[H]
[H]OC(C([H])([H])[H])(C([H])([H])[H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C2=NC3=C(N=C(N=C3N3C([H])([H])C([H])([H])OC([H])([H])C3([H])[H])N3C(=NC4=C3C([H])=C([H])C([H])=C4[H])N(C([H])([H])[H])C([H])([H])[H])N2C([H])([H])[H])C([H])([H])C1([H])[H]
[H]OC(C([H])([H])[H])(C([H])([H])[H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C2=NC3=C(N=C(N=C3N3C([H])([H])C([H])([H])OC([H])([H])C3([H])[H])N3C(=NC4=C3C([H])=C([H])C([H])=C4[H])C([H])([H])C([H])([H])[H])N2[H])C([H])([H])C1([H])[H]
[H]OC(C([H])([H])[H])(C([H])([H])[H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C2=NC3=C(S2)C(=NC(=N3)N2C(=NC3=C2C([H])=C([H])C([H])=C3[H])C([H])([H])C([H])([H])[H])N2C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]C1=C([H])C2=C(C([H])=C1[H])N(C(=N2)C([H])([H])C([H])([H])[H])C1=NC2=C(N=C(N2C([H])([H])[H])C([H])([H])N2C([H])([H])C([H])([H])N(C([H])([H])C2([H])[H])S(=O)(=O)C([H])([H])[H])C(=N1)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]OC(C([H])([H])[H])(C([H])([H])[H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C2=NC3=C(N=C(N=C3N3C([H])([H])C([H])([H])OC([H])([H])C3([H])[H])N3C4=C(N=C3[C@@]3([H])OC([H])([H])C([H])([H])C3([H])[H])C([H])=C([H])C([H])=C4[H])N2C([H])([H])[H])C([H])([H])C1([H])[H]
[H]C1=C([H])C2=C(C([H])=C1[H])N(C(=N2)C([H])([H])C([H])([H])[H])C1=NC2=C(N=C(N2C([H])([H])[H])C([H])([H])N2C([H])([H])[C@@]3([H])N(C([H])([H])[C@]2([H])C3([H])[H])C2([H])C([H])([H])OC2([H])[H])C(=N1)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]C1=C([H])C2=C(C([H])=C1[H])N(C(=N2)C([H])([H])C([H])([H])[H])C1=NC2=C(N=C(N2C([H])([H])[H])C([H])([H])N2C([H])([H])C([H])(C2([H])[H])C2([H])C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])C(=N1)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]N([H])C(=O)C(N1C([H])([H])C([H])([H])N(C([H])([H])C2=NC3=C(N=C(N=C3N3C([H])([H])C([H])([H])OC([H])([H])C3([H])[H])N3C(=NC4=C3C([H])=C([H])C([H])=C4[H])C([H])([H])C([H])([H])[H])N2C([H])([H])[H])C([H])([H])C1([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]OC(C([H])([H])[H])(C([H])([H])[H])C1([H])C([H])([H])C([H])([H])N(C2=C([H])C([H])=C3C(N=C(N=C3N3C([H])([H])C([H])([H])OC([H])([H])C3([H])[H])N3C4=C(N=C3C([H])([H])C([H])([H])[H])C([H])=C([H])C([H])=C4[H])=N2)C([H])([H])C1([H])[H]
[H]C1=C([H])C(=C(C(=C1[H])C(F)(F)F)C([H])([H])[H])C([H])([H])N1C(SC([H])([H])[H])=NN2C1=NC(=C([H])C2=O)N1C([H])([H])C([H])([H])O[C@@]([H])(C([H])([H])[H])C1([H])[H]
[H]C1=C([H])C(=C(C(=C1[H])C(F)(F)F)C([H])([H])[H])C([H])([H])N1C2=NC(=C([H])C(=O)N2N=C1C([H])([H])[H])N1C([H])([H])C([H])([H])O[C@]([H])(C([H])([H])[H])C1([H])[H]
[H]C1=C([H])C(=C(Cl)C(Cl)=C1[H])C([H])([H])N1C2=NC(=C([H])C(=O)N2N=C1C([H])([H])[H])N1C([H])([H])C([H])([H])O[C@]([H])(C([H])([H])[H])C1([H])[H]
[H]C1=NC([H])=C([H])C(=C1[H])C1=C([H])C(=O)N2N=C(SC([H])([H])[H])N(C2=N1)C([H])([H])C1=C(Cl)C(Cl)=C([H])C([H])=C1[H]
[H]C1=C([H])C(=C(C(=C1[H])C(F)(F)F)C([H])([H])[H])C([H])([H])N1C2=NC(=C([H])C(=O)N2N=C1C([H])([H])[H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]C1=C([H])C(=C(C(=C1[H])C(F)(F)F)C([H])([H])[H])C([H])([H])N1C(SC([H])([H])[H])=NN2C1=NC(=C([H])C2=O)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]C1=C([H])C(=C(C(=C1[H])C(F)(F)F)C([H])([H])[H])C([H])([H])N1C2=NC(=C([H])C(=O)N2N=C1C1([H])C([H])([H])C1([H])[H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]C1=C([H])C(=C(Cl)C(Cl)=C1[H])C([H])([H])N1C2=NC(=C([H])C(=O)N2N=C1C([H])([H])[H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]C1=C([H])C(=C(Cl)C(Cl)=C1[H])C([H])([H])N1C(SC([H])([H])[H])=NN2C1=NC(=C([H])C2=O)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]C1=C([H])C(=C(Cl)C(Cl)=C1[H])C([H])([H])N1C2=NC(=C([H])C(=O)N2N=C1C1([H])C([H])([H])C1([H])[H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]N([H])C1=NC([H])=C(C2=NC(=NC(=C2[H])N2C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])N2C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])C(=C1[H])C(F)(F)F
O=C1N=CN(CC2=CC=CC=C2)C2=C1SC(=N2)N1CCOCC1
CC1=C(C=CC=C1CN1C=NC(=O)C2=C1N=C(S2)N1CCOCC1)C(F)(F)F
CC1=C(Cl)C=CC=C1CN1C2=C(SC(=N2)N2CCOCC2)C(=O)N=C1N
CC1=C(Cl)C=CC=C1CN1C2=C(SC(=N2)N2CCOCC2)C(=O)N=C1SCC(O)=O
CSC1=NC(=O)C2=C(N=C(S2)N2CCOCC2)N1CC1=CC=CC(Cl)=C1C
CC1=C(Cl)C=CC=C1CN1C2=C(SC(=N2)N2CCOCC2)C(=O)N=C1S
COC1=NC(=O)C2=C(N=C(S2)N2CCOCC2)N1CC1=CC=CC(Cl)=C1C
CC1=C(Cl)C=CC=C1CN1C2=C(SC(=N2)N2CCOCC2)C(=O)N=C1O
CC1=C(Cl)C=CC=C1CN1C2=C(SC(=N2)N2CCOCC2)C(=O)N=C1CO
CC1=C(C=CC=C1CN1C2=C(SC(=N2)N2CCOCC2)C(=O)N=C1CN)C(F)(F)F
CC1=C(C=CC=C1CN1C2=C(SC(=N2)N2CCOCC2)C(=O)N=C1CO)C(F)(F)F
CC1=C(C=CC=C1CN1C2=C(SC(=N2)N2CCOCC2)C(=O)N=C1CC1=CC=CC=C1)C(F)(F)F
CC1=C(C=CC=C1CN1C2=C(SC(=N2)N2CCOCC2)C(=O)N=C1C1=CC=CC=C1)C(F)(F)F
CC1=C(CN2C3=C(SC(=N3)N3CCOCC3)C(=O)N=C2C2CC2)C=CC=C1C(F)(F)F
CCC1=NC(=O)C2=C(N=C(S2)N2CCOCC2)N1CC1=C(C)C(=CC=C1)C(F)(F)F
CC1=NC(=O)C2=C(N=C(S2)N2CCOCC2)N1CC1=C(C)C(Cl)=CC=C1
CC1=NC(=O)C2=C(N=C(S2)N2CCOCC2)N1CC1=C(C)C(=CC=C1)C(F)(F)F
CC1=C(Cl)C=CC=C1CN1C=NC(=O)C2=C1N=C(S2)N1CCOCC1
ClC1=C(Cl)C(CN2C=NC(=O)C3=C2N=C(S3)N2CCOCC2)=CC=C1
ClC1=CC(CN2C=NC(=O)C3=C2N=C(S3)N2CCOCC2)=CC=C1
ClC1=C(CN2C=NC(=O)C3=C2N=C(S3)N2CCOCC2)C=CS1
ClC1=CC=CC=C1CN1C=NC(=O)C2=C1N=C(S2)N1CCOCC1
O=C1N=CN(CCC2=CC=CC=C2)C2=C1SC(=N2)N1CCOCC1
CC(N1C=NC(=O)C2=C1N=C(S2)N1CCOCC1)C1=CC=CC=C1
CC1=C(CN2C=NC(=O)C3=C2N=C(S3)N2CCOCC2)C=CC=C1
CC1=C(F)C(=CC=C1C(=O)N1CCOC2=CC=C(C=C2C1)C1=CC=C(N)N=C1)S(C)(=O)=O
CC[C@H](C)[C@H](N)C(=O)N1CCN(CC1)C1=NC(=NC(=N1)N1CCOCC1)N1C(=NC2=CC=CC=C12)C(F)F
N[C@H](CC1=CC=CC=C1)C(=O)N1CCN(CC1)C1=NC(=NC(=N1)N1CCOCC1)N1C(=NC2=CC=CC=C12)C(F)F
C[C@@H](N)C(=O)N1CCN(CC1)C1=NC(=NC(=N1)N1CCOCC1)N1C(=NC2=CC=CC=C12)C(F)F
CC(=O)NCC(=O)N1CCN(CC1)C1=NC(=NC(=N1)N1CCOCC1)N1C(=NC2=CC=CC=C12)C(F)F
NCC(=O)N1CCN(CC1)C1=NC(=NC(=N1)N1CCOCC1)N1C(=NC2=CC=CC=C12)C(F)F
[H]C1=C([H])C2=C(C([H])=C1[H])N(C(=N2)C([H])([H])[H])C1=NC(=NC(=N1)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
CC(C)C1=NC2=C(C=CC=C2)N1C1=NC(=NC(=N1)N1CCOCC1)N1CCOCC1
COC1=CC2=C(C=C1)N=C(C(F)F)N2C1=NC(=NC(=N1)N1CCOCC1)N1CCOCC1
COC1=CC2=C(C=C1)N(C(=N2)C(F)F)C1=NC(=NC(=N1)N1CCOCC1)N1CCOCC1
COC1=CC2=C(C=C1)N(C(C)=N2)C1=NC(=NC(=N1)N1CCOCC1)N1CCOCC1
COC1=CC2=C(C=C1)N(C(=N2)C(C)C)C1=NC(=NC(=N1)N1CCOCC1)N1CCOCC1
COC1=CC2=C(C=C1)N=C(C)N2C1=NC(=NC(=N1)N1CCOCC1)N1CCOCC1
COC1=CC2=C(C=C1)N=C(C(C)C)N2C1=NC(=NC(=N1)N1CCOCC1)N1CCOCC1
NCCC(=O)N1CCN(CC1)C1=NC(=NC(=N1)N1CCOCC1)N1C(=NC2=CC=CC=C12)C(F)F
NCCCC[C@H](N)C(=O)N1CCN(CC1)C1=NC(=NC(=N1)N1CCOCC1)N1C(=NC2=CC=CC=C12)C(F)F
FC(F)C1=NC2=CC=CC=C2N1C1=NC(=NC(=N1)N1CCN(CC1)C(=O)[C@@H]1CCCN1)N1CCOCC1
N[C@@H](CC1=CC=C(O)C=C1)C(=O)N1CCN(CC1)C1=NC(=NC(=N1)N1CCOCC1)N1C(=NC2=CC=CC=C12)C(F)F
[H][C@@]12C[C@@](O)(CO)[C@](C)(O1)N1C3=C(C=CC=C3)C3=C1C1=C(C4=C(C=CC=C4)N21)C1=C3CNC1=O
CC(C)=CC(=O)CCC(=O)N1CCN(CC2=CC3=C(S2)C(=NC(=N3)C2=CC=CC3=C2C=NN3)N2CCOCC2)CC1
CN1CCN(CC1)C1=NC=C(C=N1)C1=CSC2=C1OC(=CC2=O)N1CCOCC1
COC(=O)C1=CC=C(C=C1)C1=CSC2=C1OC(=CC2=O)N1CCOCC1
CCOC(=O)C1=CC=C(C=C1)C1=CSC2=C1OC(=CC2=O)N1CCOCC1
O=C(NC1=CC=C(C=C1)C1=CSC2=C1OC(=CC2=O)N1CCOCC1)C1=CN=CC=C1
CNC1=CC=C(C=C1)C1=CSC2=C1OC(=CC2=O)N1CCOCC1
CC(=O)NC1=CC=C(C=C1)C1=CSC2=C1OC(=CC2=O)N1CCOCC1
FC(F)(F)C1=CC=C(C=C1)C1=CSC2=C1OC(=CC2=O)N1CCOCC1
ClC1=CC=C(C=C1Cl)C1=CSC2=C1OC(=CC2=O)N1CCOCC1
ClC1=CC=C(C=C1)C1=CSC2=C1OC(=CC2=O)N1CCOCC1
O=C1C=C(OC2=C1SC=C2CC1=CC=CC=C1)N1CCOCC1
COC1=CC(=CC=C1)C1=CSC2=C1OC(=CC2=O)N1CCOCC1
O=C1C=C(OC2=C1SC=C2C1=CC=C2OCCOC2=C1)N1CCOCC1
O=C1C=C(OC2=C1SC=C2C1=CC=C2NC=CC2=C1)N1CCOCC1
CC1=CC(=CC=C1)C1=CSC2=C1OC(=CC2=O)N1CCOCC1
CC1=CC=C(C=C1)C1=CSC2=C1OC(=CC2=O)N1CCOCC1
O=C1C=C(OC2=C1SC=C2C1=CC2=C(N1)C=CC=C2)N1CCOCC1
NC1=CC(=CC=C1)C1=CSC2=C1OC(=CC2=O)N1CCOCC1
COC1=CC=C(C=C1)C1=CSC2=C1OC(=CC2=O)N1CCOCC1
O=C1C=C(OC2=C1SC=C2C1=CC2=C(OCO2)C=C1)N1CCOCC1
O=C1C=C(OC2=C1SC=C2C1=CC=CC=C1)N1CCOCC1
C[C@H](O)C(=O)N1CCC(CC1)N1C(=O)N(C)C2=C1C1=NC(=CC=C1N=C2)C1=CC=C(C)N=C1