[H]O[C@]([H])(C([H])([H])OC1=C([H])C([H])=C([H])C2=C1C([H])([H])[C@]([H])(O[H])[C@]([H])(O[H])C2([H])[H])C([H])([H])N([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]O[C@]([H])(C([H])([H])OC1=NSN=C1N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C([H])([H])N([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]O[C@@]([H])(C([H])([H])OC1=C2C(=C(C([H])=C1[H])C([H])([H])[H])C([H])([H])C([H])([H])C2([H])[H])[C@]([H])(N([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H]
[H]OC1=C(C([H])=C(C([H])=C1[H])[C@@]([H])(O[H])C([H])([H])N([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])OC([H])([H])C([H])([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])O[H]
[H]O[C@]([H])(C1=C([H])C([H])=C(N([H])S(=O)(=O)C([H])([H])[H])C([H])=C1[H])C([H])([H])N([H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]O[C@]([H])(C([H])([H])OC1=C([H])C([H])=C([H])C([H])=C1C([H])([H])C([H])=C([H])[H])C([H])([H])N([H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]O[C@]([H])(C([H])([H])OC1=C(Cl)C([H])=C([H])C(=C1[H])C([H])([H])[H])C([H])([H])N([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]OC(=O)C([H])([H])OC1=C([H])C([H])=C(OC([H])([H])C([H])([H])N([H])C([H])([H])[C@@]([H])(O[H])C([H])([H])OC2=C([H])C([H])=C([H])C([H])=C2[H])C([H])=C1[H]
[H]O[C@]([H])(C([H])([H])OC1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])OC([H])([H])[H])C([H])([H])N([H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]O[C@]([H])(C([H])([H])OC1=C2N([H])C(=O)N([H])C2=C([H])C([H])=C1[H])C([H])([H])N([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]OC1=C(C([H])=C(C([H])=C1[H])[C@@]([H])(O[H])C([H])([H])N([H])[C@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C(=O)N([H])[H]
[H]O[C@]([H])(C([H])([H])OC1=C([H])C([H])=C([H])C2=C1C1=C([H])C([H])=C([H])C([H])=C1N2[H])C([H])([H])N([H])C([H])([H])C([H])([H])OC1=C([H])C([H])=C([H])C([H])=C1OC([H])([H])[H]
[H]O[C@]([H])(C1=C([H])C2=C([H])C([H])=C([H])C([H])=C2C([H])=C1[H])C([H])([H])N([H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]O[C@]([H])(C([H])([H])OC1=C([H])C([H])=C([H])C2=C([H])C([H])=C([H])C([H])=C12)C([H])([H])N([H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]OC1=C(C([H])=C(OC([H])([H])C([H])([H])N([H])C([H])([H])[C@]([H])(O[H])C([H])([H])OC2=C([H])C([H])=C(C([H])=C2[H])C2=NC(=C([H])N2C([H])([H])[H])C(F)(F)F)C([H])=C1[H])C(=O)N([H])[H]
[H]O[C@@]([H])(C([H])([H])OC1=C([H])C([H])=C([H])C([H])=C1C#N)C([H])([H])N([H])C([H])([H])C([H])([H])N([H])C(=O)N([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]O[C@]([H])(C([H])([H])OC1=C([H])C([H])=C(N([H])C(=O)C([H])([H])[H])C([H])=C1[H])C([H])([H])N([H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]OC1=C([H])C([H])=C(OC([H])([H])[C@]([H])(O[H])C([H])([H])N([H])C([H])([H])C([H])([H])N([H])C(=O)N2C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])C([H])=C1[H]
[H]O[C@]([H])(C([H])([H])OC1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])OC([H])([H])C([H])([H])OC([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])N([H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]O[C@]([H])(C([H])([H])OC1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])OC([H])([H])C1([H])C([H])([H])C1([H])[H])C([H])([H])N([H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]O[C@]([H])(C([H])([H])OC1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C(=O)N([H])[H])C([H])([H])N([H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]O[C@]([H])(C([H])([H])OC1=C(C([H])=C(N([H])C(=O)C([H])([H])C([H])([H])C([H])([H])[H])C([H])=C1[H])C(=O)C([H])([H])[H])C([H])([H])N([H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[C@]1([H])N([H])C([H])([H])C([H])([H])N(C2=C([H])C([H])=C([H])C([H])=C2[H])C1([H])[H]
[H]N(C1=C([H])C([H])=C(OC([H])([H])[C@@]2([H])N([H])C([H])([H])C([H])([H])N(C3=C([H])C([H])=C([H])C([H])=C3[H])C2([H])[H])C([H])=C1[H])S(=O)(=O)C([H])([H])[H]
[H]N(C1=C([H])C([H])=C(N([H])S(=O)(=O)C([H])([H])[H])C([H])=C1[H])C([H])([H])[C@@]1([H])N([H])C([H])([H])C([H])([H])N(C2=C([H])C([H])=C([H])C([H])=C2[H])C1([H])[H]
[H]N1C([H])([H])C([H])([H])N(C2=C([H])C([H])=C([H])C([H])=C2OC([H])([H])[H])C([H])([H])C1([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C(N([H])S(=O)(=O)C([H])([H])[H])C([H])=C1[H])C([H])([H])[C@@]1([H])N([H])C([H])([H])C([H])([H])N(C2=C(OC([H])([H])[H])C([H])=C([H])C([H])=C2[H])C1([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C(C([H])=C1[H])N1C([H])=NC([H])=C1[H])C([H])([H])[C@@]1([H])N([H])C([H])([H])C([H])([H])N(C2=C([H])C([H])=C([H])C([H])=C2[H])C1([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C(C([H])=C1[H])N(C([H])([H])[H])S(=O)(=O)C([H])([H])[H])C([H])([H])[C@]1([H])N([H])C([H])([H])C([H])([H])N(C2=C([H])C([H])=C([H])C([H])=C2[H])C1([H])[H]
[H]N(C([H])([H])C1=C([H])C([H])=C(N([H])S(=O)(=O)C([H])([H])[H])C([H])=C1[H])C([H])([H])[C@@]1([H])N([H])C([H])([H])C([H])([H])N(C2=C([H])C([H])=C([H])C([H])=C2[H])C1([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C(N([H])S(=O)(=O)C([H])([H])[H])C([H])=C1[H])C([H])([H])[C@]1([H])N([H])C([H])([H])C([H])([H])N(C2=C([H])C(Cl)=C([H])C([H])=C2[H])C1([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C(N([H])S(=O)(=O)C([H])([H])[H])C([H])=C1[H])C([H])([H])[C@]1([H])N([H])C([H])([H])C([H])([H])N(C2=C([H])C(OC([H])([H])[H])=C([H])C([H])=C2[H])C1([H])[H]
[H]N1C([H])([H])C([H])([H])N(C2=C([H])C(OC([H])([H])[H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N1C([H])([H])C([H])([H])N(C2=C([H])C([H])=C([H])C(Cl)=C2[H])C([H])([H])C1([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C(N([H])S(=O)(=O)C([H])([H])[H])C([H])=C1[H])C([H])([H])[C@@]1([H])N([H])C([H])([H])C([H])([H])N(C2=C([H])C([H])=C([H])C([H])=C2[H])C1([H])[H]
[H]OC1=C(O[H])C([H])=C(OC([H])([H])[C@]([H])(O[H])C([H])([H])N([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C(F)=C1[H]
[H]OC1=C(O[H])C(F)=C(OC([H])([H])[C@]([H])(O[H])C([H])([H])N([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])=C1[H]
[H]OC1=C(O[H])C([H])=C(C([H])=C1[H])[C@@]([H])(O[H])C([H])([H])N([H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]OC1=C(O[H])C([H])=C(OC([H])([H])[C@]([H])(O[H])C([H])([H])N([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])=C1[H]
[H]N1C([H])([H])C([H])([H])N(C2=NC([H])=C(N3C([H])=C([H])N=C23)C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N1C([H])([H])C([H])([H])N(C2=NC([H])=C(Br)N3C(Br)=C([H])N=C23)C([H])([H])C1([H])[H]
[H]C1=C([H])N2C(=N1)C(=NC([H])=C2Br)N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H]
[H]C1=C([H])N2C(=N1)C(=NC([H])=C2C([H])([H])[H])N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N1C([H])([H])C([H])([H])N(C2=NC([H])=C([H])N3C2=NC([H])=C3C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N1C([H])([H])C([H])([H])N(C2=NC([H])=C([H])N3C([H])=C(N=C23)C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N1C([H])([H])C([H])([H])N(C2=NC([H])=C(Br)N3C([H])=C([H])N=C23)C([H])([H])C1([H])[H]
[H]N1C([H])([H])C([H])([H])N(C2=NC([H])=C([H])N3C2=NC([H])=C3C([H])([H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]O[C@@]([H])(C([H])([H])O\N=C1\C2=C([H])C(F)=C([H])C([H])=C2[C@@]2([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@@]12OC([H])([H])[H])C([H])([H])N([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]O[C@@]([H])(C([H])([H])O\N=C1\C2=C([H])C([H])=C([H])C([H])=C2[C@]2([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@]12OC([H])([H])[H])C([H])([H])N([H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]O[C@@]([H])(C([H])([H])O\N=C1\C2=C([H])C([H])=C([H])C([H])=C2[C@]2([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@]12O[H])C([H])([H])N([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]OC([H])([H])C([H])([H])O[C@]12\C(=N/OC([H])([H])[C@]([H])(O[H])C([H])([H])N([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C3=C([H])C([H])=C([H])C([H])=C3[C@@]1([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H]
[H]N1C([H])([H])C([H])([H])N(C2=NC([H])=C(N3C2=NC([H])=C3C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]C1=C(Br)N2C([H])=C([H])N=C(N3C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C3([H])[H])C2=N1
[H]N1C([H])([H])C([H])([H])N(C2=NC([H])=C([H])N3C2=NC([H])=C3C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N1C([H])([H])C([H])([H])N(C2=NC([H])=C([H])N3C2=NC([H])=C3C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N1C([H])([H])C([H])([H])N(C2=NC([H])=C([H])N3C([H])=C([H])N=C23)C([H])([H])C1([H])[H]
[H]N1C([H])([H])C([H])([H])N(C2=NC(=C([H])N3C([H])=C([H])N=C23)C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N1C([H])([H])C([H])([H])N(C2=NC(=C([H])N3C2=NC([H])=C3C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]O[C@@]([H])(C([H])([H])O\N=C1\C2=C([H])C([H])=C([H])C([H])=C2[C@]2([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@]12OC([H])([H])[H])C([H])([H])N([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]OC1=C(O[H])C([H])=C(C([H])=C1[H])[C@@]([H])(O[H])C([H])([H])N([H])C([H])([H])[H]
[H]OC1=C([H])C([H])=C(C([H])=C1O[H])[C@@]([H])(O[H])C([H])([H])N([H])[H]
[H]O[C@@]([H])(C([H])([H])OC1=C([H])C([H])=C(N([H])S(=O)(=O)C([H])([H])[H])C([H])=C1[H])C([H])([H])N([H])C([H])([H])C([H])([H])OC1=C([H])C([H])=C(C([H])=C1[H])N1C([H])=NC([H])=C1[H]
[H]O[C@]([H])(C([H])([H])OC1=C([H])C([H])=C(N([H])S(=O)(=O)C([H])([H])[H])C([H])=C1[H])C([H])([H])N([H])C([H])([H])C([H])([H])OC1=C([H])C([H])=C(C([H])=C1[H])N1C([H])=C([H])N=C1C([H])([H])[H]
[H]O[C@]([H])(C([H])([H])OC1=C([H])C([H])=C(N([H])S(=O)(=O)C([H])([H])[H])C([H])=C1[H])C([H])([H])N([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])OC1=C([H])C([H])=C(C([H])=C1[H])N1C([H])=NC([H])=C1[H]
[H]OC1=C(O[H])C([H])=C2C(=C1[H])C([H])([H])C([H])([H])[C@@]1([H])N([H])C([H])([H])C3=C(C([H])=C([H])C([H])=C3[H])[C@]21[H]
[H]O[C@@]([H])(C([H])([H])OC1=C([H])C([H])=C([H])C2=C1C([H])([H])C([H])([H])C(=O)N2[H])C([H])([H])N([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]O[C@]([H])(C([H])([H])OC1=C2SC([H])([H])C(=O)N([H])C2=C([H])C([H])=C1[H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C([H])C([H])=C(Cl)C(=C2[H])S(=O)(=O)N([H])[H])C([H])([H])C1([H])[H]
[H]O[C@]([H])(C([H])([H])OC1=C2C([H])=C([H])C([H])=C([H])C2=C([H])C([H])=C1[H])C([H])([H])N([H])C([H])([H])C([H])([H])N([H])S(=O)(=O)C1=C([H])C([H])=C(Cl)C(=C1[H])S(=O)(=O)N([H])[H]
[H]O[C@]([H])(C([H])([H])OC1=C2C([H])=C([H])C([H])=C([H])C2=C([H])C([H])=C1[H])C([H])([H])N([H])C([H])([H])C([H])([H])N([H])C(=O)C1=C([H])C([H])=C(Cl)C(=C1[H])S(=O)(=O)N([H])[H]
[H]OC([H])([H])C([H])([H])C([H])([H])O[C@]1([H])SC2=C(N([H])C1=O)C([H])=C([H])C([H])=C2N([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]O[C@]([H])(C([H])([H])OC1=C2SC([H])([H])C(=O)N([H])C2=C([H])C([H])=C1[H])C([H])([H])N([H])C([H])([H])C([H])([H])N([H])C1=C([H])C([H])=C(Cl)C(=C1[H])S(=O)(=O)N([H])[H]
[H]O[C@]([H])(C([H])([H])OC1=C2C([H])=C([H])C([H])=C([H])C2=C([H])C([H])=C1[H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C([H])C([H])=C(Cl)C(=C2[H])S(=O)(=O)N([H])[H])C([H])([H])C1([H])[H]
[H]O[C@]([H])(C([H])([H])OC1=C2C(N([H])C(=O)C([H])([H])C2([H])[H])=C([H])C([H])=C1[H])C([H])([H])N([H])C([H])([H])C([H])([H])N([H])S(=O)(=O)C1=C([H])C([H])=C(Cl)C(=C1[H])S(=O)(=O)N([H])[H]
[H]O[C@]([H])(C([H])([H])OC1=C2SC([H])([H])C(=O)N([H])C2=C([H])C([H])=C1[H])C([H])([H])N([H])C([H])([H])C([H])([H])N([H])C(=O)C1=C([H])C([H])=C(Cl)C(=C1[H])S(=O)(=O)N([H])[H]
[H]O[C@]([H])(C([H])([H])OC1=C2SC([H])([H])C(=O)N([H])C2=C([H])C([H])=C1[H])C([H])([H])N([H])C([H])([H])C([H])([H])N([H])S(=O)(=O)C1=C([H])C([H])=C(Cl)C(=C1[H])S(=O)(=O)N([H])[H]
[H]O[C@]([H])(C([H])([H])OC1=C2C([H])=C([H])C([H])=C([H])C2=C([H])C([H])=C1[H])C([H])([H])N([H])C([H])([H])C([H])([H])N([H])C1=C([H])C([H])=C(Cl)C(=C1[H])S(=O)(=O)N([H])[H]
[H]O[C@]([H])(C([H])([H])OC1=C2C(N([H])C(=O)C([H])([H])C2([H])[H])=C([H])C([H])=C1[H])C([H])([H])N([H])C([H])([H])C([H])([H])N([H])C(=O)C1=C([H])C([H])=C(Cl)C(=C1[H])S(=O)(=O)N([H])[H]
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[H]OC1=C([H])C([H])=C(OC([H])([H])[C@@]([H])(O[H])C([H])([H])N([H])C([H])([H])C([H])([H])C2=C([H])C([H])=C(N([H])S(=O)(=O)C3=C([H])C4=C(N=C3[H])C([H])=C([H])C([H])=C4[H])C([H])=C2[H])C([H])=C1[H]
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[H]OC1=C([H])C([H])=C(OC([H])([H])[C@@]([H])(O[H])C([H])([H])N([H])C([H])([H])C([H])([H])C2=C([H])C([H])=C(N([H])S(=O)(=O)C([H])([H])C([H])([H])C([H])([H])[H])C([H])=C2[H])C([H])=C1[H]
[H]O[C@]([H])(C1=C([H])C([H])=C([H])N=C1[H])C([H])([H])N([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C(N([H])S(=O)(=O)C2=C([H])C([H])=C(N([H])C(=O)N([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])=C2[H])C([H])=C1[H]
[H]O[C@]([H])(C1=C([H])C([H])=C([H])N=C1[H])C([H])([H])N([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C(N([H])S(=O)(=O)C([H])([H])[H])C([H])=C1[H]
[H]OC1=C([H])C([H])=C(OC([H])([H])[C@@]([H])(O[H])C([H])([H])N([H])C([H])([H])C([H])([H])C2=C([H])C([H])=C(N([H])S(=O)(=O)C3=C([H])C([H])=C(N([H])C(=O)N([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])=C3[H])C([H])=C2[H])C([H])=C1[H]
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[H]OC1=C([H])C([H])=C(OC([H])([H])[C@@]([H])(O[H])C([H])([H])N([H])C([H])([H])C([H])([H])C2=C([H])C([H])=C(N([H])S(=O)(=O)C([H])(C([H])([H])[H])C([H])([H])[H])C([H])=C2[H])C([H])=C1[H]
[H]OC1=C([H])C([H])=C(OC([H])([H])[C@@]([H])(O[H])C([H])([H])N([H])C([H])([H])C([H])([H])C2=C([H])C([H])=C(N([H])S(=O)(=O)C([H])([H])C([H])([H])C3=C([H])C([H])=C([H])C([H])=C3[H])C([H])=C2[H])C([H])=C1[H]
[H]OC1=C([H])C([H])=C(OC([H])([H])[C@@]([H])(O[H])C([H])([H])N([H])C([H])([H])C([H])([H])C2=C([H])C([H])=C(N([H])S(=O)(=O)C3=C([H])C([H])=C(Cl)C([H])=C3[H])C([H])=C2[H])C([H])=C1[H]
[H]O[C@]([H])(C1=C([H])C([H])=C([H])N=C1[H])C([H])([H])N([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C(N([H])S(=O)(=O)C2=C([H])C([H])=C(N([H])C(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])=C2[H])C([H])=C1[H]
[H]O[C@]([H])(C1=C([H])C([H])=C([H])N=C1[H])C([H])([H])N([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C(N([H])S(=O)(=O)C2=C([H])C([H])=C(N([H])C(=O)OC([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])=C2[H])C([H])=C1[H]
[H]O[C@]([H])(C1=C([H])C([H])=C([H])N=C1[H])C([H])([H])N([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C(N([H])S(=O)(=O)C2=C([H])C([H])=C(N([H])C(=O)N([H])C([H])([H])[H])C([H])=C2[H])C([H])=C1[H]
[H]O[C@]([H])(C1=C([H])C([H])=C([H])N=C1[H])C([H])([H])N([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C(N([H])S(=O)(=O)C2=C([H])C([H])=C(N([H])C(=O)N([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])=C2[H])C([H])=C1[H]
[H]O[C@]([H])(C1=C([H])C([H])=C([H])N=C1[H])C([H])([H])N([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C(N([H])S(=O)(=O)C2=C([H])C([H])=C(N([H])C(=O)OC([H])([H])C([H])([H])C3=C([H])C([H])=C([H])C([H])=C3[H])C([H])=C2[H])C([H])=C1[H]
[H]O[C@]([H])(C1=C([H])C([H])=C([H])N=C1[H])C([H])([H])N([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C(N([H])S(=O)(=O)C2=C([H])C([H])=C(N([H])C(=O)N([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])=C2[H])C([H])=C1[H]
[H]OC1=C([H])C([H])=C(OC([H])([H])[C@@]([H])(O[H])C([H])([H])N([H])C([H])([H])C([H])([H])C2=C([H])C([H])=C(N([H])C(=O)C3=C([H])C([H])=C([H])C([H])=C3[H])C([H])=C2[H])C([H])=C1[H]
[H]OC1=C([H])C([H])=C(OC([H])([H])[C@@]([H])(O[H])C([H])([H])N([H])C([H])([H])C([H])([H])C2=C([H])C([H])=C(N([H])[H])C([H])=C2[H])C([H])=C1[H]
[H]OC1=C([H])C([H])=C(OC([H])([H])[C@@]([H])(O[H])C([H])([H])N([H])C([H])([H])C([H])([H])C2=C([H])C([H])=C(N([H])S(=O)(=O)C3=C([H])C([H])=C(N([H])C(=O)N(C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])=C3[H])C([H])=C2[H])C([H])=C1[H]
[H]OC1=C([H])C([H])=C(OC([H])([H])[C@@]([H])(O[H])C([H])([H])N([H])C([H])([H])C([H])([H])C2=C([H])C([H])=C(N([H])S(=O)(=O)C3=C([H])C([H])=C(N([H])C(=O)N([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])=C3[H])C([H])=C2[H])C([H])=C1[H]
[H]OC1=C([H])C([H])=C(OC([H])([H])[C@@]([H])(O[H])C([H])([H])N([H])C([H])([H])C([H])([H])C2=C([H])C([H])=C(N([H])S(=O)(=O)C3=C([H])C([H])=C(N([H])C(=O)C([H])([H])C([H])([H])C([H])([H])[H])C([H])=C3[H])C([H])=C2[H])C([H])=C1[H]
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[H]OC1=C([H])C([H])=C(OC([H])([H])[C@@]([H])(O[H])C([H])([H])N([H])C([H])([H])C([H])([H])C([H])([H])C2=C([H])C([H])=C(OC([H])([H])[H])C([H])=C2[H])C([H])=C1[H]
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[H]N(C1=C([H])C([H])=C([H])C([H])=C1[H])S(=O)(=O)C1=C([H])C2=C(C([H])=C1[H])N(C1=NC(=C([H])S1)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C2([H])[H]
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[H]O[C@]([H])(C([H])([H])OC1=C([H])C([H])=C(N=C1[H])N([H])[H])C([H])([H])N([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C(N([H])S(=O)(=O)C2=C([H])C([H])=C(C([H])=C2[H])C([H])([H])C([H])([H])[H])C([H])=C1[H]
[H]O[C@]([H])(C([H])([H])OC1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])N([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C(N([H])S(=O)(=O)C2=C([H])C([H])=C(I)C([H])=C2[H])C([H])=C1[H]
[H]O[C@]([H])(C([H])([H])OC1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])C([H])([H])N([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C(N([H])S(=O)(=O)C2=C([H])C([H])=C(I)C([H])=C2[H])C([H])=C1[H]
[H]O[C@]([H])(C1=C([H])C([H])=C([H])N=C1[H])C([H])([H])N([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C(N([H])S(=O)(=O)C2=C([H])C([H])=C(C([H])=C2[H])N2C([H])=C(N(C2=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])[H])C([H])=C1[H]
[H]O[C@]([H])(C1=C([H])C([H])=C([H])N=C1[H])C([H])([H])N([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C(N([H])S(=O)(=O)C2=C([H])C([H])=C(C([H])=C2[H])N2C([H])=C(N(C2=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])[H])C([H])=C1[H]
[H]O[C@]([H])(C1=C([H])C([H])=C([H])N=C1[H])C([H])([H])N([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C(N([H])S(=O)(=O)C2=C([H])C([H])=C(C([H])=C2[H])N2C(=O)N(C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C2=O)C([H])=C1[H]
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[H]O[C@]([H])(C1=C([H])C([H])=C([H])N=C1[H])C([H])([H])N([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C(N([H])S(=O)(=O)C2=C([H])C([H])=C(C([H])=C2[H])N2C(=O)N(C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C2([H])[H])C([H])=C1[H]
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[H]O[C@]([H])(C1=C([H])C([H])=C([H])N=C1[H])C([H])([H])N([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C(N([H])S(=O)(=O)C2=C([H])C([H])=C(C([H])=C2[H])N2N=C([H])C(=N2)C([H])([H])C2=C([H])C([H])=C(OC(F)(F)F)C([H])=C2[H])C([H])=C1[H]
[H]O[C@]([H])(C1=C([H])C([H])=C([H])N=C1[H])C([H])([H])N([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C(N([H])S(=O)(=O)C2=C([H])C([H])=C(C([H])=C2[H])N2N=C([H])C(=N2)C2=C([H])C(F)=C(OC([H])([H])[H])C([H])=C2[H])C([H])=C1[H]
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[H]O[C@]([H])(C1=C([H])C([H])=C([H])N=C1[H])C([H])([H])N([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C(N([H])S(=O)(=O)C2=C([H])C([H])=C(C([H])=C2[H])N2N=C([H])C(=N2)C2=C([H])C(F)=C(F)C([H])=C2[H])C([H])=C1[H]
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[H]O[C@]([H])(C1=C([H])C([H])=C([H])N=C1[H])C([H])([H])N([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C(N([H])S(=O)(=O)C2=C([H])C([H])=C(C([H])=C2[H])C2=NOC(=N2)C([H])([H])OC2=C([H])C([H])=C3C([H])=C([H])C([H])=C([H])C3=C2[H])C([H])=C1[H]
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[H]O[C@]([H])(C1=C([H])C([H])=C([H])N=C1[H])C([H])([H])N([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C(N([H])S(=O)(=O)C2=C([H])C([H])=C(C([H])=C2[H])C2=NOC(=N2)C([H])([H])C2=C([H])C([H])=C3C([H])=C([H])C([H])=C([H])C3=C2[H])C([H])=C1[H]
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[H]O[C@]([H])(C1=C([H])C([H])=C([H])N=C1[H])C([H])([H])N([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C(N([H])S(=O)(=O)C2=C([H])C([H])=C(C([H])=C2[H])C2=NOC(=N2)C([H])([H])OC2=C([H])C([H])=C(OC([H])([H])[H])C([H])=C2[H])C([H])=C1[H]
[H]O[C@]([H])(C1=C([H])C([H])=C([H])N=C1[H])C([H])([H])N([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C(N([H])S(=O)(=O)C2=C([H])C([H])=C(C([H])=C2[H])C2=NOC(=N2)[C@@]([H])(N([H])C(=O)OC([H])([H])[H])C2=C([H])C([H])=C(F)C([H])=C2[H])C([H])=C1[H]
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[H]OC1=C(O[H])C([H])=C2C(=C1[H])C([H])([H])C([H])([H])N([H])[C@]2([H])C([H])([H])OC1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C(N([H])S(=O)(=O)C2=C([H])C([H])=C(N([H])C(=O)N([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])=C2[H])=C([H])C([H])=C1[H]
[H]OC1=C(O[H])C([H])=C2C(=C1[H])C([H])([H])C([H])([H])N([H])[C@]2([H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C(N([H])S(=O)(=O)C2=C([H])C([H])=C(N([H])C(=O)N([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])=C2[H])=C([H])C([H])=C1[H]
[H]O[C@]([H])(C1=C([H])N=C([H])C([H])=C1[H])C([H])([H])N([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C(N([H])S(=O)(=O)C2=C([H])C([H])=C(C([H])=C2[H])C2=C([H])OC(=N2)C2=C([H])C([H])=C(F)C(F)=C2[H])C([H])=C1[H]
[H]O[C@]([H])(C1=C([H])N=C([H])C([H])=C1[H])C([H])([H])N([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C(N([H])S(=O)(=O)C2=C([H])C([H])=C(C([H])=C2[H])C2=C([H])N=C(O2)C([H])([H])C2=C([H])C(F)=C(F)C(F)=C2[H])C([H])=C1[H]
[H]O[C@]([H])(C1=C([H])N=C([H])C([H])=C1[H])C([H])([H])N([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C(N([H])S(=O)(=O)C2=C([H])C([H])=C(C([H])=C2[H])C2=C([H])N=C(O2)C([H])([H])C2=C([H])C([H])=C(F)C(F)=C2[H])C([H])=C1[H]
[H]O[C@]([H])(C1=C([H])N=C([H])C([H])=C1[H])C([H])([H])N([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C(N([H])S(=O)(=O)C2=C([H])C([H])=C(C([H])=C2[H])C2=C([H])N=C(O2)C2=C([H])C([H])=C(F)C([H])=C2[H])C([H])=C1[H]
[H]O[C@]([H])(C1=C([H])N=C([H])C([H])=C1[H])C([H])([H])N([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C(N([H])S(=O)(=O)C2=C([H])C([H])=C(C([H])=C2[H])C2=C([H])N=C(O2)C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])=C1[H]
[H]O[C@]([H])(C1=C([H])N=C([H])C([H])=C1[H])C([H])([H])N([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C(N([H])S(=O)(=O)C2=C([H])C([H])=C(C([H])=C2[H])C2=NC(=C([H])S2)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])=C1[H]
[H]OC1=NC2=C(OC([H])([H])[C@@]([H])(O[H])C([H])([H])N([H])C3([H])C([H])([H])C([H])([H])N(C4=C([H])C([H])=C(\C([H])=C5/SC(=NC5=O)N([H])C(=N[H])N(C([H])([H])[H])C([H])([H])[H])C([H])=C4[H])C([H])([H])C3([H])[H])C([H])=C([H])C([H])=C2N1[H]
[H]OC1=C(O[H])C([H])=C2C(=C1[H])C([H])([H])C([H])([H])N([H])[C@]2([H])C([H])([H])C1=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C(OC([H])([H])[H])=C1[H]
[H]OC1=C(O[H])C([H])=C2C(=C1[H])C([H])([H])C([H])([H])N([H])[C@]2([H])C([H])([H])OC1=C([H])C([H])=C(N([H])S(=O)(=O)C2=C([H])C([H])=C(N([H])C(=O)N([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])=C2[H])C([H])=C1[H]
[H]O[C@]([H])(C1=C([H])N=C([H])C([H])=C1[H])C([H])([H])N([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C(N([H])S(=O)(=O)C2=C([H])C([H])=C(C([H])=C2[H])C2=NC(=C([H])S2)C2=C([H])C([H])=C(N([H])C(=O)C([H])([H])[H])C([H])=C2[H])C([H])=C1[H]
[H]O[C@]([H])(C1=C([H])N=C([H])C([H])=C1[H])C([H])([H])N([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C(N([H])S(=O)(=O)C2=C([H])C([H])=C(C([H])=C2[H])C2=NC(=C([H])S2)C([H])([H])C2=C([H])C3=C([H])C([H])=C([H])C([H])=C3C([H])=C2[H])C([H])=C1[H]
[H]O[C@]([H])(C1=C([H])N=C([H])C([H])=C1[H])C([H])([H])N([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C(N([H])S(=O)(=O)C2=C([H])C([H])=C(C([H])=C2[H])C2=NC(=C([H])S2)C([H])([H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])=C1[H]
[H]O[C@]([H])(C1=C([H])N=C([H])C([H])=C1[H])C([H])([H])N([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C(N([H])S(=O)(=O)C2=C([H])C([H])=C(C([H])=C2[H])C2=NC(=C([H])S2)C2=C([H])C([H])=C(C([H])=C2[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])=C1[H]
[H]O[C@]([H])(C1=C([H])N=C([H])C([H])=C1[H])C([H])([H])N([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C(N([H])S(=O)(=O)C2=C([H])C([H])=C(C([H])=C2[H])C2=C([H])N=C(O2)C([H])([H])[H])C([H])=C1[H]
[H]O[C@]([H])(C1=C([H])N=C([H])C([H])=C1[H])C([H])([H])N([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C(N([H])S(=O)(=O)C2=C([H])C([H])=C(C([H])=C2[H])C2=C([H])OC(=N2)C([H])([H])OC2=C([H])C([H])=C(F)C(F)=C2[H])C([H])=C1[H]
[H]O[C@]([H])(C1=C([H])N=C([H])C([H])=C1[H])C([H])([H])N([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C(N([H])S(=O)(=O)C2=C([H])C([H])=C(C([H])=C2[H])C2=C([H])OC(=N2)C([H])([H])C([H])([H])C2([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])=C1[H]
[H]OC1=C(O[H])C([H])=C2C(=C1[H])C([H])([H])C([H])([H])N([H])[C@]2([H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C(OC([H])([H])[H])=C1[H]
[H]OC1=C([H])C2=C(C([H])=C1O[H])[C@]([H])(N([H])C([H])([H])C2([H])[H])C([H])([H])C1=C([H])C([H])=C(N([H])S(=O)(=O)C2=C([H])C([H])=C(N([H])C(=O)N([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])=C2[H])C([H])=C1[H]
[H]OC1=C([H])C([H])=C(C([H])=C1N([H])S(=O)(=O)C1=C([H])C([H])=C([H])C([H])=C1[H])[C@@]([H])(O[H])C([H])([H])N([H])C1([H])C([H])([H])C([H])([H])N(C2=C([H])C([H])=C(C([H])=C2[H])C([H])([H])[C@]2([H])SC(=O)N([H])C2=O)C([H])([H])C1([H])[H]
[H]O[C@]([H])(C([H])([H])OC1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])N([H])C1([H])C([H])([H])C([H])([H])N(C2=C([H])C([H])=C(C([H])=C2[H])C([H])([H])[C@@]2([H])SC(=O)N([H])C2=O)C([H])([H])C1([H])[H]
[H]O[C@]([H])(C1=C([H])C([H])=C([H])N=C1[H])C([H])([H])N([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C(N([H])C(\N([H])C2=C([H])C([H])=C([H])C(I)=C2[H])=C(\[H])[N+]([O-])=O)C([H])=C1[H]
[H]O[C@]([H])(C1=C([H])C([H])=C([H])N=C1[H])C([H])([H])N([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C(N([H])C(=N\C2=C([H])C3=C(C([H])=C2[H])N(C2=NC(=C([H])S2)C2=C([H])C([H])=C(OC(F)(F)F)C([H])=C2[H])C([H])([H])C3([H])[H])\N([H])C#N)C([H])=C1[H]
[H]O[C@]([H])(C1=C([H])C([H])=C([H])N=C1[H])C([H])([H])N([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C(N([H])C(\N([H])C2=C([H])C([H])=C([H])C(F)=C2[H])=C(\[H])[N+]([O-])=O)C([H])=C1[H]
[H]O[C@]([H])(C1=C([H])C([H])=C([H])N=C1[H])C([H])([H])N([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C(\N=C(/N([H])C#N)N([H])C2=C([H])C([H])=C3C(=C2[H])N(C2=NC(=C([H])S2)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C3([H])[H])C([H])=C1[H]
[H]O[C@]([H])(C1=C([H])C([H])=C([H])N=C1[H])C([H])([H])N([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C(N([H])C(\N([H])C2=C3C([H])=C([H])C([H])=C([H])C3=C([H])C([H])=C2[H])=C(\[H])[N+]([O-])=O)C([H])=C1[H]
[H]O[C@]([H])(C1=C([H])C([H])=C([H])N=C1[H])C([H])([H])N([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C(N([H])C(=N\C2=C([H])C(Cl)=C([H])C(Cl)=C2[H])\N([H])C#N)C([H])=C1[H]
[H]O[C@]([H])(C1=C([H])C([H])=C([H])N=C1[H])C([H])([H])N([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C(N([H])C(=N\C2=C3C([H])=C([H])C([H])=C([H])C3=C([H])C([H])=C2[H])\N([H])C#N)C([H])=C1[H]
[H]O[C@]([H])(C1=C([H])C([H])=C([H])N=C1[H])C([H])([H])N([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C(\N=C(/N([H])C#N)N([H])C2=C([H])C([H])=C([H])C(=C2[H])C(=O)N([H])[H])C([H])=C1[H]
[H]O[C@]([H])(C1=C([H])C([H])=C([H])N=C1[H])C([H])([H])N([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C(\N=C(/N([H])C#N)N([H])C2=C([H])C3=C(C([H])=C2[H])N(C2=NC(=C([H])S2)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C3([H])[H])C([H])=C1[H]
[H]O[C@]([H])(C1=C([H])N=C([H])C([H])=C1[H])C([H])([H])N([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C(N([H])S(=O)(=O)C2=C([H])C3=C(C([H])=C2[H])N(C2=NC(=C([H])S2)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C3([H])[H])C([H])=C1[H]
[H]O[C@]([H])(C1=C([H])C([H])=C([H])N=C1[H])C([H])([H])N([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C(\N=C(/S[H])N([H])C2=C([H])C3=C(C([H])=C2[H])N(C2=NC(=C([H])S2)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C3([H])[H])C([H])=C1[H]
[H]O[C@]([H])(C1=C([H])C([H])=C([H])N=C1[H])C([H])([H])N([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C(N([H])C(=N\C2=C([H])C([H])=C(I)C([H])=C2[H])\N([H])C#N)C([H])=C1[H]
[H]O[C@]([H])(C1=C([H])C([H])=C([H])N=C1[H])C([H])([H])N([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C(N([H])C(\N([H])C2=C([H])C([H])=C([H])C(=C2[H])C(=O)N([H])[H])=C(\[H])[N+]([O-])=O)C([H])=C1[H]
[H]O[C@]([H])(C1=C([H])C([H])=C([H])N=C1[H])C([H])([H])N([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C(N([H])C(\N([H])C2=C([H])C([H])=C([H])C(OC3=C([H])C([H])=C([H])C([H])=C3[H])=C2[H])=C(\[H])[N+]([O-])=O)C([H])=C1[H]
[H]O[C@]([H])(C1=C([H])C([H])=C([H])N=C1[H])C([H])([H])N([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C(N([H])C(=N\C2=C([H])C(I)=C([H])C([H])=C2[H])\N([H])C#N)C([H])=C1[H]
[H]O[C@]([H])(C1=C([H])C([H])=C([H])N=C1[H])C([H])([H])N([H])C([H])([H])C([H])([H])C1=C([H])C2=C([H])C([H])=C(N([H])C(=N\C3=C([H])C4=C(C([H])=C3[H])N(C3=NC(=C([H])S3)C3=C([H])C([H])=C(OC(F)(F)F)C([H])=C3[H])C([H])([H])C4([H])[H])\N([H])C#N)C([H])=C2C([H])=C1[H]
[H]OC1=C([H])C([H])=C(O[C@@]([H])(O[H])C([H])([H])N([H])C2([H])C([H])([H])C([H])([H])N(C3=C([H])C([H])=C(C([H])=C3[H])C([H])([H])[C@]3([H])SC(=O)N([H])C3=O)C([H])([H])C2([H])[H])C([H])=C1N([H])S(=O)(=O)C([H])([H])[H]
[H]O[C@]([H])(C([H])([H])OC1=C([H])C([H])=C([H])C2=NC(=O)N=C12)C([H])([H])N([H])C1([H])C([H])([H])C([H])([H])N(C2=C([H])C([H])=C(C([H])=C2[H])C([H])([H])[C@@]2([H])SC(=O)N([H])C2=O)C([H])([H])C1([H])[H]
[H]OC1=C([H])C([H])=C(C([H])=C1N([H])S(=O)(=O)C([H])([H])[H])[C@@]([H])(O[H])C([H])([H])N([H])C1([H])C([H])([H])C([H])([H])N(C2=C([H])C([H])=C(C([H])=C2[H])C([H])([H])[C@@]2([H])SC(=O)N([H])C2=O)C([H])([H])C1([H])[H]
[H]OC1=C([H])C([H])=C2C(O[C@@]([H])(O[H])C([H])([H])N([H])C3([H])C([H])([H])C([H])([H])N(C4=C([H])C([H])=C(C([H])=C4[H])C([H])([H])[C@]4([H])SC(=O)N([H])C4=O)C([H])([H])C3([H])[H])=C([H])C([H])=C([H])C2=N1
[H]OC1=C([H])C([H])=C(OC([H])([H])[C@@]([H])(O[H])C([H])([H])N([H])C2([H])C([H])([H])C([H])([H])N(C3=C([H])C([H])=C(C([H])=C3[H])C([H])([H])[C@@]3([H])SC(=O)N([H])C3=O)C([H])([H])C2([H])[H])C([H])=C1[H]
[H]O[C@]([H])(C1=C([H])C([H])=C([H])N=C1[H])C([H])([H])N([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C(N([H])C(=N\C2=C([H])C([H])=C([H])C3=C2C([H])([H])C([H])([H])N3C2=NC(=C([H])S2)C2=C([H])C([H])=C(OC(F)(F)F)C([H])=C2[H])\N([H])C#N)C([H])=C1[H]
[H]O[C@]([H])(C1=C([H])C([H])=C([H])N=C1[H])C([H])([H])N([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C(N([H])C(=N\C2=C([H])C([H])=C3C(=C2[H])N(C2=NC(=C([H])S2)C2=C([H])C([H])=C(OC(F)(F)F)C([H])=C2[H])C([H])([H])C3([H])[H])\N([H])C#N)C([H])=C1[H]
[H]O[C@]([H])(C1=C([H])C([H])=C([H])N=C1[H])C([H])([H])N([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C(N([H])C(\N([H])C2=C([H])C(Cl)=C([H])C(Cl)=C2[H])=C(\[H])[N+]([O-])=O)C([H])=C1[H]
[H]O[C@]([H])(C1=C([H])C([H])=C([H])N=C1[H])C([H])([H])N([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C(N([H])C(=N\C2=C([H])C(F)=C([H])C([H])=C2[H])\N([H])C#N)C([H])=C1[H]
[H]O[C@]([H])(C1=C([H])C([H])=C([H])N=C1[H])C([H])([H])N([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C(N([H])C(=N\C2=C([H])C(OC3=C([H])C([H])=C([H])C([H])=C3[H])=C([H])C([H])=C2[H])\N([H])C#N)C([H])=C1[H]
[H]OC1=C([H])C([H])=C(C([H])=C1N([H])S(=O)(=O)C([H])([H])[H])[C@@]([H])(O[H])C([H])([H])N([H])C1([H])C([H])([H])C([H])([H])N(C2=C([H])C([H])=C(C([H])=C2[H])C(=O)N([H])[H])C([H])([H])C1([H])[H]
[H]OC(=O)C([H])([H])OC([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])N1C([H])([H])C([H])([H])C([H])(N([H])C([H])([H])[C@]([H])(O[H])C2=C([H])C([H])=C(O[H])C(N([H])S(=O)(=O)C([H])([H])[H])=C2[H])C([H])([H])C1([H])[H]
[H]OC(=O)C([H])([H])N(C(=O)C1=C([H])C([H])=C(C([H])=C1[H])N1C([H])([H])C([H])([H])C([H])(N([H])C([H])([H])[C@]([H])(O[H])C2=C([H])C([H])=C(O[H])C(N([H])S(=O)(=O)C([H])([H])[H])=C2[H])C([H])([H])C1([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]OC(=O)C([H])([H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])N1C([H])([H])C([H])([H])C([H])(N([H])C([H])([H])[C@]([H])(O[H])C2=C([H])C([H])=C(O[H])C(N([H])S(=O)(=O)C([H])([H])[H])=C2[H])C([H])([H])C1([H])[H]
[H]OC(=O)C([H])([H])C(=O)N([H])C1=C([H])C([H])=C(C([H])=C1[H])N1C([H])([H])C([H])([H])C([H])(N([H])C([H])([H])[C@]([H])(O[H])C2=C([H])C([H])=C(O[H])C(N([H])S(=O)(=O)C([H])([H])[H])=C2[H])C([H])([H])C1([H])[H]
[H]OC1=NC2=C(OC([H])([H])[C@@]([H])(O[H])C([H])([H])N([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])=C([H])C([H])=C2N1[H]
[H]OC1=C([H])C([H])=C(C([H])=C1N([H])S(=O)(=O)C([H])([H])[H])[C@@]([H])(O[H])C([H])([H])N([H])C1([H])C([H])([H])C([H])([H])N(C2=C([H])C([H])=C(C([H])=C2[H])C(=O)N([H])C([H])([H])C(=O)OC([H])([H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]OC(=O)C([H])([H])S(=O)(=O)N(C1=C([H])C([H])=C(C([H])=C1[H])N1C([H])([H])C([H])([H])C([H])(N([H])C([H])([H])[C@]([H])(O[H])C2=C([H])C([H])=C(O[H])C(N([H])S(=O)(=O)C([H])([H])[H])=C2[H])C([H])([H])C1([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]O[C@]([H])(C1=C([H])C([H])=C([H])N=C1[H])C([H])([H])N([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C(\N=C(/N([H])C#N)N([H])C2=C([H])C([H])=C([H])C3=C2C([H])([H])C([H])([H])N3C2=NC(=C([H])S2)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])=C1[H]
[H]OC1=C([H])C([H])=C(OC([H])([H])[C@@]([H])(O[H])C([H])([H])N([H])C([H])([H])C([H])([H])C2=C([H])C([H])=C(N([H])C3([H])C([H])([H])C([H])([H])N(C(=O)N([H])C([H])([H])C4=C(F)C([H])=C([H])C(F)=C4[H])C([H])([H])C3([H])[H])C([H])=C2[H])C([H])=C1N([H])S(=O)(=O)C([H])([H])[H]
[H]OC1=C([H])C([H])=C(OC([H])([H])[C@@]([H])(O[H])C([H])([H])N([H])C([H])([H])C([H])([H])C2=C([H])C([H])=C(N([H])C3([H])C([H])([H])C([H])([H])N(C(=O)N([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C3([H])[H])C([H])=C2[H])C([H])=C1[H]
[H]OC1=C([H])C([H])=C(OC([H])([H])[C@@]([H])(O[H])C([H])([H])N([H])C([H])([H])C([H])([H])C2=C([H])C([H])=C(N([H])C3([H])C([H])([H])C([H])([H])N(C(=O)N([H])C([H])([H])C4=C([H])C([H])=C(Cl)C([H])=C4Cl)C([H])([H])C3([H])[H])C([H])=C2[H])C([H])=C1[H]
[H]OC1=C2N([H])C(=O)C([H])([H])C([H])([H])C2=C(OC([H])([H])[C@@]([H])(O[H])C([H])([H])N([H])C([H])([H])C([H])([H])C2=C([H])C([H])=C(N([H])C3([H])C([H])([H])C([H])([H])N(C(=O)N([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C3([H])[H])C([H])=C2[H])C([H])=C1[H]
[H]OC1=C([H])C([H])=C(C([H])=C1N([H])S(=O)(=O)C([H])([H])[H])[C@@]([H])(O[H])C([H])([H])N([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C(N([H])C2([H])C([H])([H])C([H])([H])N(C(=O)N([H])C([H])([H])C3=C(F)C([H])=C([H])C(F)=C3[H])C([H])([H])C2([H])[H])C([H])=C1[H]
[H]OC1=C([H])C([H])=C(OC([H])([H])[C@@]([H])(O[H])C([H])([H])N([H])C([H])([H])C([H])([H])C2=C([H])C([H])=C(N([H])C3([H])C([H])([H])C([H])([H])N(C(=O)N([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C3([H])[H])C([H])=C2[H])C([H])=C1[H]
[H]OC1=C([H])C([H])=C(OC([H])([H])[C@@]([H])(O[H])C([H])([H])N([H])C([H])([H])C([H])([H])C2=C([H])C([H])=C(N([H])C3([H])C([H])([H])C([H])([H])N(C(=O)N([H])C([H])([H])C4=C(F)C([H])=C([H])C([H])=C4F)C([H])([H])C3([H])[H])C([H])=C2[H])C([H])=C1[H]
[H]OC1=C([H])C([H])=C(OC([H])([H])[C@@]([H])(O[H])C([H])([H])N([H])C([H])([H])C([H])([H])C2=C([H])C([H])=C(N([H])C3([H])C([H])([H])C([H])([H])N(C(=O)N([H])C4([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C4([H])[H])C([H])([H])C3([H])[H])C([H])=C2[H])C([H])=C1[H]
[H]OC1=C([H])C([H])=C(OC([H])([H])[C@@]([H])(O[H])C([H])([H])N([H])C([H])([H])C([H])([H])C2=C([H])C([H])=C(N([H])C3([H])C([H])([H])C([H])([H])N(C(=O)N([H])C([H])([H])C4=C([H])C([H])=C([H])C([H])=C4F)C([H])([H])C3([H])[H])C([H])=C2[H])C([H])=C1[H]
[H]OC1=C([H])C([H])=C(OC([H])([H])[C@@]([H])(O[H])C([H])([H])N([H])C([H])([H])C([H])([H])C2=C([H])C([H])=C(N([H])C3([H])C([H])([H])C([H])([H])N(C(=O)N([H])[H])C([H])([H])C3([H])[H])C([H])=C2[H])C([H])=C1[H]
[H]OC1=C([H])C([H])=C(OC([H])([H])[C@@]([H])(O[H])C([H])([H])N([H])C([H])([H])C([H])([H])C2=C([H])C([H])=C(N([H])C3([H])C([H])([H])C([H])([H])N(C(=O)N([H])C([H])([H])[H])C([H])([H])C3([H])[H])C([H])=C2[H])C([H])=C1[H]
[H]OC1=C([H])C([H])=C(OC([H])([H])[C@@]([H])(O[H])C([H])([H])N([H])C([H])([H])C([H])([H])C2=C([H])C([H])=C(N([H])C3([H])C([H])([H])C([H])([H])N(C(=O)N([H])C([H])([H])C4=C([H])C([H])=C(F)C([H])=C4[H])C([H])([H])C3([H])[H])C([H])=C2[H])C([H])=C1[H]
[H]OC1=C([H])C([H])=C(OC([H])([H])[C@@]([H])(O[H])C([H])([H])N([H])C([H])([H])C([H])([H])C2=C([H])C([H])=C(N([H])C3([H])C([H])([H])C([H])([H])N(C(=O)N([H])C([H])([H])C4=C([H])C(F)=C([H])C([H])=C4F)C([H])([H])C3([H])[H])C([H])=C2[H])C([H])=C1[H]
[H]OC1=C([H])C([H])=C(OC([H])([H])[C@@]([H])(O[H])C([H])([H])N([H])C([H])([H])C([H])([H])C2=C([H])C([H])=C(N([H])C3([H])C([H])([H])C([H])([H])N(C(=O)N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H])C([H])([H])C3([H])[H])C([H])=C2[H])C([H])=C1[H]
[H]OC1=C([H])C([H])=C(OC([H])([H])[C@@]([H])(O[H])C([H])([H])N([H])C([H])([H])C([H])([H])C2=C([H])C([H])=C(N([H])C3([H])C([H])([H])C([H])([H])N(C(=O)N([H])C([H])([H])C4=C([H])C([H])=C(F)C([H])=C4F)C([H])([H])C3([H])[H])C([H])=C2[H])C([H])=C1[H]
[H]N1C(=O)C2(N(C3=C([H])C([H])=C([H])C([H])=C3[H])C1([H])[H])C([H])([H])C([H])([H])N(C([H])([H])C1=C([H])C([H])=C([H])C(OC3=C([H])C([H])=C([H])C([H])=C3[H])=C1[H])C([H])([H])C2([H])[H]
[H]OC1=C([H])C([H])=C(OC([H])([H])[C@@]([H])(O[H])C([H])([H])N([H])C([H])([H])C2([H])C([H])([H])C([H])([H])N(C([H])([H])C2([H])[H])S(=O)(=O)C2=C([H])C([H])=C(N([H])C(=O)N([H])C([H])([H])C3=C([H])C(F)=C([H])C([H])=C3F)C([H])=C2[H])C([H])=C1F
[H]OC1=C([H])C([H])=C(OC([H])([H])[C@@]([H])(O[H])C([H])([H])N([H])C([H])([H])C2([H])C([H])([H])C([H])([H])N(C([H])([H])C2([H])[H])S(=O)(=O)C2=C([H])C([H])=C(N([H])C(=O)N([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])=C2[H])C([H])=C1[H]
[H]OC1=C([H])C([H])=C(OC([H])([H])[C@@]([H])(O[H])C([H])([H])N([H])C([H])([H])C2([H])C([H])([H])C([H])([H])N(C([H])([H])C2([H])[H])S(=O)(=O)C2=C([H])C([H])=C(N([H])C(=O)N([H])C3=C([H])C([H])=C([H])C([H])=C3[H])C([H])=C2[H])C([H])=C1[H]
[H]O[C@]([H])(C([H])([H])OC1=C([H])C([H])=C([H])C2=C1C1=C(N2[H])C([H])=C([H])C([H])=C1[H])C([H])([H])N([H])C([H])([H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]OC(=O)C([H])([H])C1=C([H])N(C2=C([H])C([H])=C([H])C([H])=C12)C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)N1C([H])([H])C([H])([H])C([H])(C([H])([H])N([H])C([H])([H])[C@]([H])(O[H])C2=C([H])C([H])=C(O[H])C(N([H])S(=O)(=O)C([H])([H])[H])=C2[H])C([H])([H])C1([H])[H]
[H]OC1=C([H])C([H])=C(C([H])=C1N([H])S(=O)(=O)C([H])([H])[H])[C@@]([H])(O[H])C([H])([H])N([H])C([H])([H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])S(=O)(=O)C1=C([H])C([H])=C(N([H])C(=O)N([H])C([H])([H])C2=C(F)C([H])=C([H])C(F)=C2[H])C([H])=C1[H]
[H]OC(=O)[C@@]([H])(N([H])C(=O)N([H])C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)N1C([H])([H])C([H])([H])C([H])(C([H])([H])N([H])C([H])([H])[C@]([H])(O[H])C2=C([H])C([H])=C(O[H])C(N([H])S(=O)(=O)C([H])([H])[H])=C2[H])C([H])([H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC1=C([H])C([H])=C(C([H])=C1N([H])S(=O)(=O)C([H])([H])[H])[C@@]([H])(O[H])C([H])([H])N([H])C([H])([H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])S(=O)(=O)C1=C([H])C([H])=C(N([H])C(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])=C1[H]
[H]OC(=O)C1=C2C([H])=C([H])N(C2=C([H])C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)N1C([H])([H])C([H])([H])C([H])(C([H])([H])N([H])C([H])([H])[C@]([H])(O[H])C2=C([H])C([H])=C(O[H])C(N([H])S(=O)(=O)C([H])([H])[H])=C2[H])C([H])([H])C1([H])[H]
[H]OC(=O)C1=C([H])N(N=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)N1C([H])([H])C([H])([H])C([H])(C([H])([H])N([H])C([H])([H])[C@]([H])(O[H])C2=C([H])C([H])=C(O[H])C(N([H])S(=O)(=O)C([H])([H])[H])=C2[H])C([H])([H])C1([H])[H]
[H]OC1=C([H])C([H])=C(OC([H])([H])[C@@]([H])(O[H])C([H])([H])N([H])C([H])([H])C2([H])C([H])([H])C([H])([H])N(C([H])([H])C2([H])[H])S(=O)(=O)C2=C([H])C([H])=C(N([H])C(=O)N([H])C([H])([H])C3=C([H])C(F)=C([H])C([H])=C3F)C([H])=C2[H])C([H])=C1[H]
[H]O[C@]([H])(C([H])([H])OC1=C([H])C([H])=C([H])C2=C1C1=C(N2[H])C([H])=C([H])C([H])=C1[H])C([H])([H])N([H])C([H])([H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C(F)(F)F)C([H])([H])C1([H])[H]
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[H]OC1=C([H])C([H])=C(OC([H])([H])[C@@]([H])(O[H])C([H])([H])N([H])C([H])([H])C2([H])C([H])([H])C([H])([H])N(C([H])([H])C2([H])[H])S(=O)(=O)C2=C([H])C([H])=C(N([H])C(=O)N([H])C([H])([H])C3=C([H])C(F)=C([H])C([H])=C3F)C([H])=C2[H])C([H])=C1N([H])S(=O)(=O)C([H])([H])[H]
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[H]OC1=C(N([H])S(=O)(=O)C([H])([H])[H])C([H])=C(C([H])=C1[H])C([H])([H])[C@@]([H])(O[H])C([H])([H])N([H])[C@]([H])(C1=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C([H])=C1[H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C(Cl)=C1[H]
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[H]O[C@]([H])(C1=C([H])C([H])=C([H])N=C1[H])C([H])([H])N([H])C([H])([H])C([H])([H])OC1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])OC(=N1)C([H])(C([H])([H])[H])C([H])([H])[H]
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[H]O[C@]([H])(C1=C([H])C([H])=C([H])N=C1[H])C([H])([H])N([H])C([H])([H])C([H])([H])OC1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])SC(=N1)C([H])([H])[H]
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[H]O[C@]([H])(C1=C([H])C([H])=C([H])N=C1[H])C([H])([H])N([H])C([H])([H])C([H])([H])OC1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])OC([H])=N1
[H]O[C@]([H])(C1=C([H])C([H])=C([H])N=C1[H])C([H])([H])N([H])C([H])([H])C([H])([H])OC1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])OC(=N1)C([H])([H])OC([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]O[C@]([H])(C1=C([H])C([H])=C([H])N=C1[H])C([H])([H])N([H])C([H])([H])C([H])([H])OC1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])SC(=N1)C([H])([H])C([H])([H])[H]
[H]O[C@]([H])(C1=C([H])C([H])=C([H])N=C1[H])C([H])([H])N([H])C([H])([H])C([H])([H])OC1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])SC([H])=N1
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[H]OC(=O)C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[C@]([H])(N([H])C([H])([H])[C@]([H])(O[H])C1=C([H])C([H])=C([H])N=C1[H])C([H])([H])[H]
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[H]O[C@@]([H])(C([H])([H])OC1=C([H])C([H])=C([H])C2=C1C([H])=C([H])N2[H])C([H])([H])N([H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]O[C@]([H])(C([H])([H])OC1=C([H])C([H])=C([H])C2=C1C([H])=C([H])N2[H])C([H])([H])N([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
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[H]OC(=O)C1=C([H])C([H])=C(C([H])=C1OC([H])(C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])N([H])C([H])([H])[C@]([H])(O[H])C1=C([H])C(Cl)=C([H])C([H])=C1[H]
[H]OC(=O)C1=C([H])C([H])=C(C([H])=C1OC1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])N([H])C([H])([H])[C@]([H])(O[H])C1=C([H])C([H])=C(N=C1[H])N([H])[H]
[H]OC(=O)C1=C([H])C([H])=C(C([H])=C1C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])N([H])C([H])([H])[C@]([H])(O[H])C1=C([H])C([H])=C(N=C1[H])N([H])[H]
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[H]OC(=O)C1=C([H])C([H])=C(C([H])=C1OC([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C(OC([H])([H])C([H])([H])N([H])C([H])([H])[C@]([H])(O[H])C2=C([H])C(Cl)=C([H])C([H])=C2[H])C([H])=C1[H]
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[H]OC(=O)C1=C([H])C([H])=C(C([H])=C1OC([H])([H])C([H])([H])C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])N([H])C([H])([H])[C@]([H])(O[H])C1=C([H])C(Cl)=C([H])C([H])=C1[H]
[H]OC(=O)C1=C([H])C([H])=C(C([H])=C1OC1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C(OC([H])([H])C([H])([H])N([H])C([H])([H])[C@]([H])(O[H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])=C1[H]
[H]OC(=O)C1=C([H])C([H])=C(C([H])=C1OC([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C(OC([H])([H])C([H])([H])N([H])C([H])([H])[C@]([H])(O[H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])=C1[H]
[H]OC(=O)C1=C([H])C([H])=C(C([H])=C1OC([H])(C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C(OC([H])([H])C([H])([H])N([H])C([H])([H])[C@]([H])(O[H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])=C1[H]
[H]OC(=O)C1=C([H])C([H])=C(C([H])=C1OC1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C(OC([H])([H])C([H])([H])N([H])C([H])([H])[C@]([H])(O[H])C2=C([H])C(Cl)=C([H])C([H])=C2[H])C([H])=C1[H]
[H]OC(=O)C1=C([H])C([H])=C(C([H])=C1OC([H])(C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])N([H])C([H])([H])[C@]([H])(O[H])C1=C([H])C(O[H])=C([H])C([H])=C1[H]
[H]OC(=O)C1=C([H])C([H])=C(C([H])=C1OC([H])(C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])N([H])C([H])([H])[C@]([H])(O[H])C1=C([H])C(F)=C([H])C([H])=C1[H]
[H]OC(=O)C1=C([H])C([H])=C(C([H])=C1OC([H])(C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])N([H])C([H])([H])[C@]([H])(O[H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]OC(=O)C1=C([H])C([H])=C(C([H])=C1OC1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])N([H])C([H])([H])[C@]([H])(O[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC(=O)C1=C([H])C([H])=C(C([H])=C1C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])N([H])C([H])([H])[C@]([H])(O[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC(=O)C1=C([H])C([H])=C(C([H])=C1OC([H])(C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])N([H])C([H])([H])[C@]([H])(O[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC(=O)C1=C([H])C([H])=C(C([H])=C1OC1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])N([H])C([H])([H])[C@]([H])(O[H])C1=C([H])C(Cl)=C([H])C([H])=C1[H]
[H]OC(=O)C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C2=C(C([H])=C1[H])C([H])([H])C([H])([H])[C@]([H])(N([H])C([H])([H])[C@]([H])(O[H])C1=C([H])C([H])=C(C#N)C([H])=C1[H])C2([H])[H]
[H]OC(=O)C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C2=C(C([H])=C1[H])C([H])([H])C([H])([H])[C@]([H])(N([H])C([H])([H])[C@]([H])(O[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H])C2([H])[H]
[H]OC(=O)C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C2=C(C([H])=C1[H])C([H])([H])C([H])([H])[C@]([H])(N([H])C([H])([H])[C@]([H])(O[H])C1=C([H])C([H])=C(Cl)C([H])=C1[H])C2([H])[H]
[H]OC(=O)C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C2=C(C([H])=C1[H])C([H])([H])C([H])([H])[C@]([H])(N([H])C([H])([H])[C@]([H])(O[H])C1=C(Cl)C([H])=C([H])C([H])=C1[H])C2([H])[H]
[H]OC(=O)C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C2=C(C([H])=C1[H])C([H])([H])C([H])([H])[C@]([H])(N([H])C([H])([H])[C@]([H])(O[H])C1=C([H])C([H])=C(C([H])=C1[H])C(F)(F)F)C2([H])[H]
[H]OC(=O)C1=C([H])C([H])=C(C(F)=C1[H])C1=C([H])C2=C(C([H])=C1[H])C([H])([H])C([H])([H])[C@]([H])(N([H])C([H])([H])[C@]([H])(O[H])C1=C([H])C([H])=C(Cl)C([H])=C1[H])C2([H])[H]
[H]OC(=O)C1=C([H])C([H])=C(C2=C([H])C3=C(C([H])=C2[H])C([H])([H])C([H])([H])[C@]([H])(N([H])C([H])([H])[C@]([H])(O[H])C2=C([H])C([H])=C(Cl)C([H])=C2[H])C3([H])[H])C(=C1[H])C([H])([H])[H]
[H]OC(=O)C1=C([H])C([H])=C(C([H])=C1OC([H])(C([H])([H])[H])C([H])([H])[H])C1=C([H])C2=C(C([H])=C1[H])C([H])([H])C([H])([H])[C@]([H])(N([H])C([H])([H])[C@]([H])(O[H])C1=C([H])C([H])=C(Cl)C([H])=C1[H])C2([H])[H]
[H]OC(=O)C1=C([H])C([H])=C(C([H])=C1OC([H])([H])[H])C1=C([H])C2=C(C([H])=C1[H])C([H])([H])C([H])([H])[C@]([H])(N([H])C([H])([H])[C@]([H])(O[H])C1=C([H])C([H])=C(Cl)C([H])=C1[H])C2([H])[H]
[H]OC(=O)C1=C([H])C([H])=C(C([H])=C1F)C1=C([H])C2=C(C([H])=C1[H])C([H])([H])C([H])([H])[C@]([H])(N([H])C([H])([H])[C@]([H])(O[H])C1=C([H])C([H])=C(Cl)C([H])=C1[H])C2([H])[H]
[H]OC(=O)C1=C([H])C([H])=C(C([H])=C1C([H])([H])[H])C1=C([H])C2=C(C([H])=C1[H])C([H])([H])C([H])([H])[C@]([H])(N([H])C([H])([H])[C@]([H])(O[H])C1=C([H])C([H])=C(Cl)C([H])=C1[H])C2([H])[H]
[H]OC(=O)C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C2=C(C([H])=C1[H])C([H])([H])C([H])([H])[C@]([H])(N([H])C([H])([H])[C@]([H])(O[H])C1=C([H])C([H])=C(Cl)N=C1[H])C2([H])[H]
[H]OC(=O)C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C2=C(C([H])=C1[H])C([H])([H])C([H])([H])[C@]([H])(N([H])C([H])([H])[C@]([H])(O[H])C1=C([H])C([H])=C([H])N=C1[H])C2([H])[H]
[H]OC(=O)C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C2=C(C([H])=C1[H])C([H])([H])C([H])([H])[C@]([H])(N([H])C([H])([H])[C@]([H])(O[H])C1=C([H])C(Cl)=C(Cl)C([H])=C1[H])C2([H])[H]
[H]O[C@]([H])(C([H])([H])OC1=C([H])C(=C([H])C([H])=C1[H])C([H])([H])[H])C([H])([H])N([H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]OC(=O)C([H])([H])OC1=C([H])C(OC2=C([H])C3=C(C([H])=C2[H])C([H])([H])C([H])([H])[C@]([H])(N([H])C([H])([H])[C@]([H])(O[H])C2=C([H])C(Cl)=C([H])C([H])=C2[H])C3([H])[H])=C([H])C([H])=C1[H]
[H]OC(=O)C1=C([H])C(OC2=C([H])C3=C(C([H])=C2[H])C([H])([H])C([H])([H])[C@]([H])(N([H])C([H])([H])[C@]([H])(O[H])C2=C([H])C([H])=C(Cl)N=C2[H])C3([H])[H])=C([H])C([H])=C1[H]
[H]OC(=O)C1=C([H])C(OC2=C([H])C3=C(C([H])=C2[H])C([H])([H])C([H])([H])[C@]([H])(N([H])C([H])([H])[C@]([H])(O[H])C2=C([H])C([H])=C(Cl)N=C2[H])C3([H])[H])=C([H])C([H])=C1OC([H])([H])[H]
[H]OC(=O)C1=C([H])C(OC2=C([H])C3=C(C([H])=C2[H])C([H])([H])C([H])([H])[C@]([H])(N([H])C([H])([H])[C@]([H])(O[H])C2=C([H])C([H])=C(Cl)N=C2[H])C3([H])[H])=C([H])C(=C1[H])N(C([H])([H])[H])C([H])([H])[H]
[H]OC(=O)C1=C([H])C(OC2=C([H])C3=C(C([H])=C2[H])C([H])([H])C([H])([H])[C@]([H])(N([H])C([H])([H])[C@]([H])(O[H])C2=C([H])C(Cl)=C([H])C([H])=C2[H])C3([H])[H])=C([H])C([H])=C1[H]
[H]OC(=O)C1=C([H])C(OC2=C([H])C3=C(C([H])=C2[H])C([H])([H])C([H])([H])C([H])([H])[C@]([H])(N([H])C([H])([H])[C@]([H])(O[H])C2=C([H])C(Cl)=C([H])C([H])=C2[H])C3([H])[H])=C([H])C([H])=C1[H]
[H]OC(=O)C1=C([H])C([H])=C(OC2=C([H])C3=C(C([H])=C2[H])C([H])([H])C([H])([H])[C@]([H])(N([H])C([H])([H])[C@]([H])(O[H])C2=C([H])C(Cl)=C([H])C([H])=C2[H])C3([H])[H])C([H])=C1[H]
[H]OC(=O)C1=C([H])C(OC2=C([H])C([H])=C(C([H])=C2[H])C([H])([H])C([H])([H])N([H])C([H])([H])[C@]([H])(O[H])C2=C([H])C(Cl)=C([H])C([H])=C2[H])=C([H])C([H])=C1[H]
[H]O[C@]([H])(C1=C([H])C(Cl)=C([H])C([H])=C1[H])C([H])([H])N([H])[C@]1([H])C([H])([H])C2=C(C([H])=C([H])C(OC([H])([H])C(=O)OC([H])([H])C([H])([H])[H])=C2[H])C([H])([H])C([H])([H])C1([H])[H]
[H]OC(=O)C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])N([H])C([H])([H])[C@]([H])(O[H])C1=C([H])C(Cl)=C([H])C([H])=C1[H]
[H]OC(=O)C1=C([H])C([H])=C(OC2=C([H])C3=C(C([H])=C2[H])C([H])([H])C([H])([H])[C@]([H])(N([H])C([H])([H])[C@]([H])(O[H])C2=C([H])C(Cl)=C([H])C([H])=C2[H])C3([H])[H])N=C1[H]
[H]OC(=O)C1=C([H])C([H])=C(OC2=C([H])C3=C(C([H])=C2[H])C([H])([H])C([H])([H])C([H])([H])[C@]([H])(N([H])C([H])([H])[C@]([H])(O[H])C2=C([H])C(Cl)=C([H])C([H])=C2[H])C3([H])[H])C([H])=C1[H]
[H]OC(=O)C1=C(OC2=C([H])C3=C(C([H])=C2[H])C([H])([H])C([H])([H])[C@]([H])(N([H])C([H])([H])[C@]([H])(O[H])C2=C([H])C(Cl)=C([H])C([H])=C2[H])C3([H])[H])N=C([H])C([H])=C1[H]
[H]OC(=O)C1=C([H])C([H])=C([H])C(=C1[H])C1=C([H])C2=C(C([H])=C1[H])C([H])([H])C([H])([H])[C@]([H])(N([H])C([H])([H])[C@]([H])(O[H])C1=C([H])C(Cl)=C([H])C([H])=C1[H])C2([H])[H]
[H]OC(=O)C([H])([H])OC1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C2=C(C([H])=C1[H])C([H])([H])C([H])([H])[C@]([H])(N([H])C([H])([H])[C@]([H])(O[H])C1=C([H])C(Cl)=C([H])C([H])=C1[H])C2([H])[H]
[H]OC(=O)C([H])([H])OC1=C([H])C([H])=C([H])C(=C1[H])C1=C([H])C2=C(C([H])=C1[H])C([H])([H])C([H])([H])[C@]([H])(N([H])C([H])([H])[C@]([H])(O[H])C1=C([H])C(Cl)=C([H])C([H])=C1[H])C2([H])[H]
[H]OC(=O)C1=C([H])C([H])=C(OC2=C([H])C3=C(C([H])=C2[H])C([H])([H])C([H])([H])[C@]([H])(N([H])C([H])([H])[C@]([H])(O[H])C2=C([H])C(Cl)=C([H])C([H])=C2[H])C3([H])[H])S1
[H]OC(=O)C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C2=C(C([H])=C1[H])C([H])([H])C([H])([H])[C@]([H])(N([H])C([H])([H])[C@]([H])(O[H])C1=C([H])C(Cl)=C([H])C([H])=C1[H])C2([H])[H]
[H]OC(=O)C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C2=C(C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])[C@]([H])(N([H])C([H])([H])[C@]([H])(O[H])C1=C([H])C(Cl)=C([H])C([H])=C1[H])C2([H])[H]
[H]OC(=O)C([H])([H])OC1=C([H])C2=C(C([H])=C1[H])C([H])([H])C([H])([H])[C@]([H])(N([H])C([H])([H])[C@]([H])(O[H])C1=C([H])C(Cl)=C([H])C([H])=C1[H])C2([H])[H]
[H]OC(=O)C1=C([H])C([H])=C(S1)C1=C([H])C2=C(C([H])=C1[H])C([H])([H])C([H])([H])[C@]([H])(N([H])C([H])([H])[C@]([H])(O[H])C1=C([H])C(Cl)=C([H])C([H])=C1[H])C2([H])[H]
[H]OC(=O)C1=C([H])C([H])=C(N=C1[H])C1=C([H])C2=C(C([H])=C1[H])C([H])([H])C([H])([H])[C@]([H])(N([H])C([H])([H])[C@]([H])(O[H])C1=C([H])C(Cl)=C([H])C([H])=C1[H])C2([H])[H]
[H]OC(=O)C1=C([H])C([H])=C(OC2=C([H])C([H])=C(C([H])=C2[H])C([H])([H])C([H])([H])N([H])C([H])([H])[C@]([H])(O[H])C2=C([H])C(Cl)=C([H])C([H])=C2[H])C([H])=C1[H]
[H]OC(=O)C1=C([H])C([H])=C(OC2=C([H])C(=C([H])C([H])=C2[H])C([H])([H])C([H])([H])N([H])C([H])([H])[C@]([H])(O[H])C2=C([H])C(Cl)=C([H])C([H])=C2[H])C([H])=C1[H]
[H]OC(=O)C1=C([H])C(OC2=C([H])C(=C([H])C([H])=C2[H])C([H])([H])C([H])([H])N([H])C([H])([H])[C@]([H])(O[H])C2=C([H])C(Cl)=C([H])C([H])=C2[H])=C([H])C([H])=C1[H]
[H]OC(=O)C1=C([H])C(OC2=C([H])C(=C([H])C([H])=C2[H])C([H])([H])C([H])([H])N([H])C([H])([H])[C@]([H])(O[H])C2=C([H])C(Cl)=C([H])C([H])=C2[H])=C([H])C([H])=C1F
[H]OC(=O)C1=C([H])C(OC2=C([H])C(=C([H])C([H])=C2[H])C([H])([H])C([H])([H])N([H])C([H])([H])[C@]([H])(O[H])C2=C([H])C(Cl)=C([H])C([H])=C2[H])=C([H])C([H])=C1Cl
[H]OC(=O)C1=C([H])C(OC2=C([H])C(=C([H])C([H])=C2[H])C([H])([H])C([H])([H])N([H])C([H])([H])[C@]([H])(O[H])C2=C([H])C(Cl)=C([H])C([H])=C2[H])=C([H])C([H])=C1C([H])([H])[H]
[H]OC(=O)C1=C([H])C(OC2=C([H])C(=C([H])C([H])=C2[H])C([H])([H])C([H])([H])N([H])C([H])([H])[C@]([H])(O[H])C2=C([H])C(Cl)=C([H])C([H])=C2[H])=C([H])C([H])=C1OC([H])([H])[H]
[H]OC(=O)C1=C([H])C(OC2=C([H])C(=C([H])C([H])=C2[H])C([H])([H])C([H])([H])N([H])C([H])([H])[C@]([H])(O[H])C2=C([H])C(Cl)=C([H])C([H])=C2[H])=C([H])C([H])=C1OC([H])(C([H])([H])[H])C([H])([H])[H]
[H]OC(=O)C1=C([H])C(OC2=C([H])C(=C([H])C([H])=C2[H])C([H])([H])C([H])([H])N([H])C([H])([H])[C@]([H])(O[H])C2=C([H])C(Cl)=C([H])C([H])=C2[H])=C([H])C([H])=C1N([H])C(=O)C([H])([H])[H]
[H]OC(=O)C1=C([H])C(OC2=C([H])C(=C([H])C([H])=C2[H])C([H])([H])C([H])([H])N([H])C([H])([H])[C@]([H])(O[H])C2=C([H])C(Cl)=C([H])C([H])=C2[H])=C([H])C([H])=C1N([H])C(=O)C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC(=O)C1=C([H])C(OC2=C([H])C(=C([H])C([H])=C2[H])C([H])([H])C([H])([H])N([H])C([H])([H])[C@]([H])(O[H])C2=C([H])C(Cl)=C([H])C([H])=C2[H])=C([H])C([H])=C1N([H])C(=O)C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]OC(=O)C1=C([H])C(OC2=C([H])C(=C([H])C([H])=C2[H])C([H])([H])C([H])([H])N([H])C([H])([H])[C@]([H])(O[H])C2=C([H])C(Cl)=C([H])C([H])=C2[H])=C([H])C([H])=C1N1C(=O)C([H])([H])C([H])([H])C1([H])[H]
[H]OC(=O)C1=C([H])C(OC2=C([H])C(=C([H])C([H])=C2[H])C([H])([H])C([H])([H])N([H])C([H])([H])[C@]([H])(O[H])C2=C([H])C(Cl)=C([H])C([H])=C2[H])=C([H])C(N([H])C(=O)C([H])([H])[H])=C1[H]
[H]OC(=O)C1=C([H])C(OC2=C([H])C(=C([H])C([H])=C2[H])C([H])([H])C([H])([H])N([H])C([H])([H])[C@]([H])(O[H])C2=C([H])C(Cl)=C([H])C([H])=C2[H])=C([H])C(N([H])C(=O)C2=C([H])C([H])=C([H])C([H])=C2[H])=C1[H]
[H]OC(=O)C1=C([H])C(OC2=C([H])C(=C([H])C([H])=C2[H])C([H])([H])C([H])([H])N([H])C([H])([H])[C@]([H])(O[H])C2=C([H])C([H])=C([H])N=C2[H])=C([H])C([H])=C1F
[H]OC(=O)C1=C([H])C(OC2=C([H])C(=C([H])C([H])=C2[H])C([H])([H])C([H])([H])N([H])C([H])([H])[C@]([H])(O[H])C2=C([H])C([H])=C([H])N=C2[H])=C([H])C([H])=C1OC([H])([H])[H]
[H]OC(=O)C1=C([H])C(OC2=C([H])C(=C([H])C([H])=C2[H])C([H])([H])C([H])([H])N([H])C([H])([H])[C@]([H])(O[H])C2=C([H])C([H])=C([H])N=C2[H])=C([H])C([H])=C1N([H])C(=O)C([H])([H])[H]
[H]OC(=O)C1=C([H])C(OC2=C([H])C(=C([H])C([H])=C2[H])C([H])([H])[C@]([H])(N([H])C([H])([H])[C@]([H])(O[H])C2=C([H])C(Cl)=C([H])C([H])=C2[H])C([H])([H])[H])=C([H])C([H])=C1[H]
[H]OC(=O)[C@]([H])(OC1=C([H])C([H])=C([H])C(=C1[H])C([H])([H])N1C2=C([H])C(OC(F)(F)F)=C([H])C([H])=C2C(C(=O)C2=C([H])C([H])=C(Cl)C([H])=C2[H])=C1C([H])([H])[H])C([H])([H])[H]
[H]OC1=C([H])C([H])=C(OC([H])([H])[C@@]([H])(O[H])C([H])([H])N([H])C([H])([H])C([H])([H])C2=C([H])C([H])=C(N([H])C(=O)C([H])([H])C3=C([H])C([H])=C([H])C([H])=N3)C([H])=C2[H])C([H])=C1[H]
[H]O[C@]([H])(C([H])([H])OC1=C([H])C([H])=C([H])N=C1[H])C([H])([H])N([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C(N([H])C(=O)C([H])([H])C2=C([H])C([H])=C([H])C([H])=N2)C([H])=C1[H]
[H]O[C@]([H])(C([H])([H])OC1=C([H])C([H])=C([H])C2=C1N([H])C(=O)N2[H])C([H])([H])N([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C(N([H])C(=O)C([H])([H])C2=C([H])C([H])=C([H])C([H])=N2)C([H])=C1[H]
[H]O[C@]([H])(C([H])([H])OC1=C([H])C([H])=C([H])C2=C1C([H])=C([H])N2[H])C([H])([H])N([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C(N([H])C(=O)C([H])([H])C2=C([H])C([H])=C([H])C([H])=N2)C([H])=C1[H]
[H]O[C@]([H])(C([H])([H])OC1=C([H])C([H])=C([H])C2=C1C1=C(N2[H])C([H])=C([H])C([H])=C1[H])C([H])([H])N([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C(N([H])C(=O)C([H])([H])C2=C([H])C([H])=C([H])C([H])=N2)C([H])=C1[H]
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[H]OC1=C([H])C([H])=C(OC([H])([H])[C@@]([H])(O[H])C([H])([H])N([H])C([H])([H])C([H])([H])C2=C([H])C([H])=C(N([H])C(=O)C([H])([H])C3=C([H])SC([H])=C3[H])C([H])=C2[H])C([H])=C1[H]
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[H]O[C@]([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])N([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C(C(=O)N([H])S(=O)(=O)C([H])([H])[H])C(OC2([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])=C1[H]
[H]O[C@]([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])N([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C(C(=O)N([H])S(=O)(=O)C([H])([H])[H])C(OC([H])(C([H])([H])[H])C([H])([H])[H])=C1[H]
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[H]O[C@]([H])(C([H])([H])OC1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])N([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C(N([H])C(=O)C([H])([H])C2=C([H])N(C([H])=N2)C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])=C1[H]
[H]O[C@]([H])(C([H])([H])OC1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])N([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C(N([H])C(=O)C([H])([H])C2=NC([H])=C([H])N2C([H])([H])C2=C([H])C([H])=C(Cl)C([H])=C2[H])C([H])=C1[H]
[H]O[C@]([H])(C([H])([H])OC1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])N([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C(N([H])C(=O)C([H])([H])C2=NC([H])=C([H])N2C([H])([H])C2=C([H])C([H])=C(Br)C([H])=C2[H])C([H])=C1[H]
[H]O[C@]([H])(C([H])([H])OC1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])N([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C(N([H])C(=O)C([H])([H])C2=NC([H])=C([H])N2C([H])([H])C2=C([H])C([H])=C3C([H])=C([H])C([H])=C([H])C3=C2[H])C([H])=C1[H]
[H]O[C@]([H])(C([H])([H])OC1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])N([H])[C@@]([H])(C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(N([H])C(=O)C([H])([H])C2=NC([H])=C([H])N2C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])=C1[H]
[H]O[C@]([H])(C([H])([H])OC1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])N([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])N(C(=O)C([H])([H])C1=NC([H])=C([H])N1C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H]
[H]O[C@]([H])(C([H])([H])OC1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])N([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])N(C(=O)C([H])([H])C1=NC([H])=C([H])N1C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]O[C@]([H])(C([H])([H])OC1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])N([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C2N(C(=O)C([H])([H])C3=NC([H])=C([H])N3C([H])([H])C3=C([H])C([H])=C([H])C([H])=C3[H])C([H])([H])C([H])([H])C([H])([H])C2=C1[H]
[H]O[C@@]([H])(C([H])([H])OC1=C([H])C([H])=C2N(C([H])([H])C3=C([H])C([H])=C([H])C([H])=C3[H])C([H])([H])C([H])([H])C([H])([H])C2=C1[H])C([H])([H])N([H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]O[C@]([H])(C([H])([H])OC1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])N([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C(N([H])C(=O)C([H])([H])C2=C(C([H])=C([H])C([H])=N2)C([H])([H])[H])C([H])=C1[H]
[H]O[C@]([H])(C([H])([H])OC1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])N([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C(N([H])C(=O)C([H])([H])C2=C([H])C(=C([H])C(=N2)C([H])([H])[H])C([H])([H])[H])C([H])=C1[H]
[H]O[C@]([H])(C([H])([H])OC1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])N([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C(N([H])C(=O)C([H])([H])C2=C([H])C([H])=C([H])C(Cl)=N2)C([H])=C1[H]
[H]O[C@]([H])(C([H])([H])OC1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])N([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C(N([H])C(=O)C([H])([H])C2=C([H])C([H])=C([H])C(OC([H])([H])C3=C([H])C([H])=C([H])C([H])=C3[H])=N2)C([H])=C1[H]
[H]O[C@]([H])(C([H])([H])OC1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])N([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C(N([H])C(=O)C([H])([H])C2=NC([H])=C([H])N2[H])C([H])=C1[H]
[H]O[C@]([H])(C([H])([H])OC1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])N([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C(N([H])C(=O)C([H])([H])C2=NC([H])=C([H])N2C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])=C1[H]
[H]O[C@]([H])(C([H])([H])OC1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])N([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C(N([H])C(=O)C([H])([H])C2=NC([H])=C([H])N2C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])=C1[H]
[H]O[C@]([H])(C([H])([H])OC1=C2N([H])C(=O)N([H])C2=C([H])C([H])=C1[H])C([H])([H])N([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]O[C@]([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])N([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C(C(=O)N([H])S(=O)(=O)C([H])([H])[H])C(=C1[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]OC(=O)C1=C([H])C([H])=C(C([H])=C1OC([H])(C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])N([H])C([H])([H])[C@]([H])(O[H])C1=C([H])N=C([H])C([H])=C1N([H])[H]
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[H]O[C@]([H])(C1=C([H])N=C([H])C([H])=C1N([H])[H])C([H])([H])N([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C(C(=O)N([H])S(=O)(=O)C([H])([H])[H])C(SC([H])(C([H])([H])[H])C([H])([H])[H])=C1[H]
[H]O[C@]([H])(C1=C([H])N=C([H])C([H])=C1N([H])[H])C([H])([H])N([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C(C(=O)N([H])S(=O)(=O)C([H])([H])[H])C(OC2([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])=C1[H]
[H]O[C@]([H])(C1=C([H])N=C([H])C([H])=C1N([H])[H])C([H])([H])N([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C(C(=O)N([H])S(=O)(=O)C([H])([H])[H])C(OC([H])(C([H])([H])[H])C([H])([H])[H])=C1[H]
[H]O[C@]([H])(C1=C([H])N=C([H])C([H])=C1N([H])[H])C([H])([H])N([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C(C(=O)N([H])S(=O)(=O)C([H])([H])[H])C(OC([H])([H])C([H])([H])[H])=C1[H]
[H]O[C@]([H])(C1=C([H])C([H])=C(N([H])[H])C([H])=C1[H])C([H])([H])N([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C(C(=O)N([H])S(=O)(=O)C([H])([H])[H])C(OC2([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])=C1[H]
[H]O[C@]([H])(C1=C([H])C([H])=C(N([H])[H])C([H])=C1[H])C([H])([H])N([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C(C(=O)N([H])S(=O)(=O)C([H])([H])[H])C(OC([H])(C([H])([H])[H])C([H])([H])[H])=C1[H]
[H]O[C@]([H])(C1=C([H])N=C([H])C([H])=C1[H])C([H])([H])N([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C(C(=O)N([H])S(=O)(=O)C([H])([H])[H])C(SC([H])(C([H])([H])[H])C([H])([H])[H])=C1[H]
[H]O[C@]([H])(C1=C([H])N=C([H])C([H])=C1[H])C([H])([H])N([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C(C(=O)N([H])S(=O)(=O)C([H])([H])[H])C(=C1[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]O[C@]([H])(C1=C([H])N=C([H])C([H])=C1[H])C([H])([H])N([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C(C(=O)N([H])S(=O)(=O)C([H])([H])[H])C(=C1[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H]
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[H]O[C@]([H])(C1=C([H])N=C([H])C([H])=C1[H])C([H])([H])N([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C(C(=O)N([H])S(=O)(=O)C([H])([H])[H])C(N([H])C([H])(C([H])([H])[H])C([H])([H])[H])=C1[H]
[H]O[C@]([H])(C1=C([H])N=C([H])C([H])=C1[H])C([H])([H])N([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C(C(=O)N([H])S(=O)(=O)C([H])([H])[H])C(OC2([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])=C1[H]
[H]O[C@]([H])(C1=C([H])N=C([H])C([H])=C1[H])C([H])([H])N([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C(C(=O)N([H])S(=O)(=O)C([H])([H])[H])C(OC([H])(C([H])([H])[H])C([H])([H])[H])=C1[H]
[H]O[C@]([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])N([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C(C(=O)N([H])S(=O)(=O)C([H])([H])[H])C(SC2([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])=C1[H]
[H]O[C@]([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])N([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C(C(=O)N([H])S(=O)(=O)C([H])([H])[H])C(SC([H])(C([H])([H])[H])C([H])([H])[H])=C1[H]
[H]O[C@]([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])N([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C(C(=O)N([H])S(=O)(=O)C([H])([H])[H])C(SC([H])([H])C([H])([H])C([H])([H])[H])=C1[H]
[H]OC(=O)C([H])([H])C([H])([H])C1=C([H])N=C(S1)C([H])([H])[C@]([H])(N([H])C([H])([H])[C@]([H])(O[H])C([H])([H])OC1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H]
[H]OC(=O)C([H])([H])C([H])([H])C([H])([H])C1=C([H])N=C(S1)C([H])([H])[C@]([H])(N([H])C([H])([H])[C@]([H])(O[H])C1=C([H])C(Cl)=C([H])C([H])=C1[H])C([H])([H])[H]
[H]OC(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1=C([H])N=C(S1)C([H])([H])[C@]([H])(N([H])C([H])([H])[C@]([H])(O[H])C([H])([H])OC1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H]
[H]OC(=O)C([H])([H])C([H])([H])C([H])([H])C1=C([H])N=C(S1)C([H])([H])[C@]([H])(N([H])C([H])([H])[C@]([H])(O[H])C([H])([H])OC1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H]
[H]O[C@]([H])(C1=C([H])C(Cl)=C([H])C([H])=C1[H])C([H])([H])N([H])[C@]([H])(C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(OC([H])([H])C(=O)OC([H])([H])[H])C([H])=C1[H]
[H]O[C@]([H])(C1=C([H])C(Cl)=C([H])C([H])=C1[H])C([H])([H])N([H])[C@]([H])(C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(OC([H])([H])S(=O)(=O)O[H])C([H])=C1[H]
[H]ON([H])C(=O)C([H])([H])OC1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[C@]([H])(N([H])C([H])([H])[C@]([H])(O[H])C1=C([H])C(Cl)=C([H])C([H])=C1[H])C([H])([H])[H]
[H]O[C@]([H])(C1=C([H])C(Cl)=C([H])C([H])=C1[H])C([H])([H])N([H])[C@]([H])(C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(OC([H])([H])C(=O)N([H])[H])C([H])=C1[H]
[H]OC([H])([H])C([H])([H])OC1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[C@]([H])(N([H])C([H])([H])[C@]([H])(O[H])C1=C([H])C(Cl)=C([H])C([H])=C1[H])C([H])([H])[H]
[H]O[C@@]([H])(C([H])([H])N([H])C([H])(C([H])([H])[H])C([H])([H])[H])C(F)(F)OC1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])OC([H])([H])[H]
[H]O[C@@]([H])(C([H])([H])OC1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])N([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)N([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]O[C@]([H])(C([H])([H])OC1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])N([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C(N([H])C(=S)N([H])C2=C([H])C([H])=C([H])C([H])=C2OC([H])([H])[H])C([H])=C1[H]
[H]O[C@]([H])(C([H])([H])OC1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])N([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C(N([H])C(=N\C#N)\N([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])=C1[H]
[H]N(C(=O)N1C([H])([H])[C@@]([H])(C([H])=C2C3=C([H])C([H])=C([H])C4=C3C(=C([H])N4[H])C([H])([H])[C@@]12[H])C(=O)N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC1=C([H])C(=C2OC([H])([H])C(=O)N([H])C2=C1[H])[C@]([H])(O[H])C([H])([H])N([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(OC([H])([H])C([H])([H])[H])C([H])=C1[H]
[H]OC1=C([H])C(=C2OC([H])([H])C(=O)N([H])C2=C1[H])[C@]([H])(O[H])C([H])([H])N([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]C1=C2OC([H])([H])OC2=C([H])C2=C1C1=C3C(=C([H])C(OC([H])([H])[H])=C1OC([H])([H])[H])C([H])([H])C([H])([H])N(C([H])([H])[H])[C@@]3([H])C2([H])[H]
[H]OC1=C2N([H])C(=O)C([H])([H])OC2=C(C([H])=C1[H])[C@]([H])(O[H])C([H])([H])N([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C(F)(F)F
[H]OC1=C2N([H])C(=O)C([H])([H])OC2=C(C([H])=C1[H])[C@]([H])(O[H])C([H])([H])N([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(OC(F)(F)F)C([H])=C1[H]
[H]OC1=C2N([H])C(=O)C([H])([H])OC2=C(C([H])=C1[H])[C@]([H])(O[H])C([H])([H])N([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C1=C([H])C(F)=C([H])C(F)=C1[H]
[H]OC1=C2N([H])C(=O)C([H])([H])OC2=C(C([H])=C1[H])[C@]([H])(O[H])C([H])([H])N([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C(=C1[H])C(F)(F)F
[H]OC1=C2N([H])C(=O)C([H])([H])OC2=C(C([H])=C1[H])[C@]([H])(O[H])C([H])([H])N([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C(=C1[H])C([H])([H])[H]
[H]OC1=C2N([H])C(=O)C([H])([H])OC2=C(C([H])=C1[H])[C@]([H])(O[H])C([H])([H])N([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]OC(=O)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C(N([H])C([H])([H])[C@@]([H])(O[H])C1=C2OC([H])([H])C(=O)N([H])C2=C(O[H])C([H])=C1[H])(C([H])([H])[H])C([H])([H])[H]
[H]OC1=C([H])C([H])=C(C([H])=C1N([H])C([H])=O)[C@@]([H])(O[H])C([H])([H])N([H])[C@]([H])(C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]OC(=O)C1=C([H])C(=C([H])C([H])=C1[H])C([H])([H])C(N([H])C([H])([H])[C@@]([H])(O[H])C1=C2OC([H])([H])C(=O)N([H])C2=C(O[H])C([H])=C1[H])(C([H])([H])[H])C([H])([H])[H]
[H]OC1=C2N([H])C(=O)C([H])([H])OC2=C(C([H])=C1[H])[C@]([H])(O[H])C([H])([H])N([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1C([H])([H])[H]
[H]OC1=C2N([H])C(=O)C([H])([H])OC2=C(C([H])=C1[H])[C@]([H])(O[H])C([H])([H])N([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C(N([H])C([H])([H])[C@@]([H])(O[H])C1=C2OC([H])([H])C(=O)N([H])C2=C(O[H])C([H])=C1[H])(C([H])([H])[H])C([H])([H])[H]
[H]OC1=C2N([H])C(=O)C([H])([H])OC2=C(C([H])=C1[H])[C@]([H])(O[H])C([H])([H])N([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC1=C(C([H])=C(C([H])=C1[H])[C@]([H])(O[H])C([H])([H])N([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1C([H])([H])[H])C([H])([H])O[H]
[H]O[C@@]([H])(C1=C([H])C(Cl)=C(N([H])[H])C(Cl)=C1[H])C([H])([H])N([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C1=C([H])C(F)=C([H])C(F)=C1[H]
[H]O[C@@]([H])(C1=C([H])C(Cl)=C(N([H])[H])C(Cl)=C1[H])C([H])([H])N([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])[H]
[H]OC1=C(C([H])=C(C([H])=C1[H])[C@]([H])(O[H])C([H])([H])N([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C(=C1[H])C(F)(F)F)C([H])([H])O[H]
[H]O[C@]([H])(C1=C([H])C([H])=C([H])N=C1[H])C([H])([H])N([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C(N([H])C(=O)C2=C([H])C([H])=C([H])C([H])=C2C2([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])=C1[H]
[H]O[C@]([H])(C1=C([H])C([H])=C([H])N=C1[H])C([H])([H])N([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C(N([H])C(=O)C2=C([H])C([H])=C([H])C([H])=C2C([H])([H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])=C1[H]
[H]O[C@]([H])(C1=C([H])C([H])=C([H])N=C1[H])C([H])([H])N([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C(N([H])C(=O)C2=C([H])C([H])=C([H])C([H])=C2C2=NC3=C(N2[H])C([H])=C([H])C([H])=C3[H])C([H])=C1[H]
[H]O[C@]([H])(C1=C([H])C([H])=C([H])N=C1[H])C([H])([H])N([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C(N([H])C(=O)C2=C([H])C([H])=C([H])C([H])=C2C([H])([H])OC2=C([H])C([H])=C([H])C([H])=C2[H])C([H])=C1[H]
[H]O[C@]([H])(C1=C([H])C([H])=C([H])N=C1[H])C([H])([H])N([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C(N([H])C(=O)C2=C([H])C(=C([H])C([H])=C2[H])C2=NC([H])=C([H])N2[H])C([H])=C1[H]
[H]O[C@]([H])(C1=C([H])C([H])=C([H])N=C1[H])C([H])([H])N([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C(N([H])C(=O)C2=C([H])C(=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])=C1[H]
[H]O[C@]([H])(C1=C([H])C([H])=C([H])N=C1[H])C([H])([H])N([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C(N([H])C(=O)C2=C([H])C([H])=C(C([H])=C2[H])C([H])([H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])=C1[H]
[H]OC1=C([H])C(=C2OC([H])([H])C(=O)N([H])C2=C1[H])[C@]([H])(O[H])C([H])([H])N([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1C(F)(F)F
[H]OC1=C([H])C(=C2OC([H])([H])C(=O)N([H])C2=C1[H])[C@]([H])(O[H])C([H])([H])N([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(Br)C([H])=C1[H]
[H]OC1=C([H])C(=C2OC([H])([H])C(=O)N([H])C2=C1[H])[C@]([H])(O[H])C([H])([H])N([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]OC1=C([H])C(=C2OC([H])([H])C(=O)N([H])C2=C1[H])[C@]([H])(O[H])C([H])([H])N([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]OC1=C([H])C(=C2OC([H])([H])C(=O)N([H])C2=C1[H])[C@]([H])(O[H])C([H])([H])N([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(OC(F)(F)F)C([H])=C1[H]
[H]OC1=C([H])C(=C2OC([H])([H])C(=O)N([H])C2=C1[H])[C@]([H])(O[H])C([H])([H])N([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C(=C1[H])C(F)(F)F
[H]OC1=C([H])C(=C2OC([H])([H])C(=O)N([H])C2=C1[H])[C@]([H])(O[H])C([H])([H])N([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C(F)(F)F
[H]OC1=C([H])C(=C2OC([H])([H])C(=O)N([H])C2=C1[H])[C@]([H])(O[H])C([H])([H])N([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C1=C([H])C(F)=C([H])C(F)=C1[H]
[H]OC1=C([H])C(=C2OC([H])([H])C(=O)N([H])C2=C1[H])[C@]([H])(O[H])C([H])([H])N([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC1=C([H])C(=C2OC([H])([H])C(=O)N([H])C2=C1[H])[C@]([H])(O[H])C([H])([H])N([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]OC1=C([H])C(=C2OC([H])([H])C(=O)N([H])C2=C1[H])[C@]([H])(O[H])C([H])([H])N([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1C([H])([H])[H]
[H]OC1=C([H])C(=C2OC([H])([H])C(=O)N([H])C2=C1[H])[C@]([H])(O[H])C([H])([H])N([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
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[H]O[C@@]([H])(C([H])([H])OC1=C(C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])=C([H])[H])C([H])([H])N1C([H])([H])C([H])([H])C([H])(C([H])([H])N2C(=O)C3=C(C([H])=C([H])C([H])=C3[H])C2=O)C([H])([H])C1([H])[H]
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[H]O[C@]([H])(C([H])([H])OC1=C(C([H])=C([H])C([H])=C1[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])N1C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])N2C(=O)C3=C([H])C([H])=C([H])C4=C([H])C([H])=C([H])C(C2=O)=C34)C([H])([H])C1([H])[H]
[H]OC1=C([H])C(=C2OC([H])([H])C(=O)N([H])C2=C1[H])[C@]([H])(O[H])C([H])([H])N([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(N([H])C(=O)C([H])([H])C([H])([H])C([H])([H])N([H])[H])C([H])=C1[H]
[H]OC1=C2N([H])C(=O)C([H])([H])OC2=C(C([H])=C1[H])[C@]([H])(O[H])C([H])([H])N([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(N([H])C(=O)C([H])([H])C([H])([H])C([H])([H])N([H])C(=O)C([H])([H])N(C([H])([H])[H])C([H])([H])[H])C([H])=C1[H]
[H]OC1=C2N([H])C(=O)C([H])([H])OC2=C(C([H])=C1[H])[C@]([H])(O[H])C([H])([H])N([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(N([H])C(=O)C([H])([H])C([H])([H])C([H])([H])N([H])C([H])([H])C([H])([H])C([H])([H])S(=O)(=O)O[H])C([H])=C1[H]
[H]OC1=C2N([H])C(=O)C([H])([H])OC2=C(C([H])=C1[H])[C@]([H])(O[H])C([H])([H])N([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(N([H])C(=O)C([H])([H])C([H])([H])C([H])([H])N([H])C(=O)C([H])([H])C([H])([H])N([H])[H])C([H])=C1[H]
[H]OC1=C2N([H])C(=O)C([H])([H])OC2=C(C([H])=C1[H])[C@]([H])(O[H])C([H])([H])N([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(N([H])C(=O)C([H])([H])C([H])([H])C([H])([H])N([H])[H])C([H])=C1[H]
[H]OC1=C2N([H])C(=O)C([H])([H])OC2=C(C([H])=C1[H])[C@]([H])(O[H])C([H])([H])N([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(N([H])C(=O)C([H])([H])C([H])([H])C([H])([H])N([H])C(=N[H])N([H])[H])C([H])=C1[H]
[H]OC1=C2N([H])C(=O)C([H])([H])OC2=C(C([H])=C1[H])[C@]([H])(O[H])C([H])([H])N([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(N([H])C(=O)C([H])([H])C([H])([H])C([H])([H])N([H])C(=O)C([H])([H])N([H])[H])C([H])=C1[H]
[H]OC1=C2N([H])C(=O)C([H])([H])OC2=C(C([H])=C1[H])[C@]([H])(O[H])C([H])([H])N([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(N([H])C(=O)C([H])([H])C([H])([H])C([H])([H])N([H])C(=O)C([H])([H])N2C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C2([H])[H])C([H])=C1[H]
[H]OC1=C([H])C(=C2OC([H])([H])C(=O)N([H])C2=C1[H])[C@]([H])(O[H])C([H])([H])N([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C(OC([H])([H])[H])=C1[H]
[H]OC(=O)C1=C([H])C(OC2=C([H])C3=C(C([H])=C2[H])C([H])([H])C([H])([H])[C@]([H])(N([H])C([H])([H])[C@]([H])(O[H])C2=C([H])C(Cl)=C([H])C([H])=C2[H])C3([H])[H])=C([H])C([H])=C1C([H])([H])[H]
[H]OC(=O)C1=C([H])C(OC2=C([H])C3=C(C([H])=C2[H])C([H])([H])C([H])([H])[C@]([H])(N([H])C([H])([H])[C@]([H])(O[H])C2=C([H])C(Cl)=C([H])C([H])=C2[H])C3([H])[H])=C([H])C([H])=C1Cl
[H]OC(=O)C1=C([H])C(OC2=C([H])C3=C(C([H])=C2[H])C([H])([H])C([H])([H])[C@]([H])(N([H])C([H])([H])[C@]([H])(O[H])C2=C([H])C(Cl)=C([H])C([H])=C2[H])C3([H])[H])=C([H])C([H])=C1OC([H])([H])[H]
[H]OC(=O)C1=C([H])C(OC2=C([H])C3=C(C([H])=C2[H])C([H])([H])C([H])([H])[C@]([H])(N([H])C([H])([H])[C@]([H])(O[H])C2=C([H])C(Cl)=C([H])C([H])=C2[H])C3([H])[H])=C([H])C(OC([H])([H])[H])=C1[H]
[H]OC(=O)C1=C([H])C(OC2=C([H])C3=C(C([H])=C2[H])C([H])([H])C([H])([H])[C@]([H])(N([H])C([H])([H])[C@]([H])(O[H])C2=C([H])C(Cl)=C([H])C([H])=C2[H])C3([H])[H])=C([H])C(N([H])[H])=C1[H]
[H]OC(=O)C1=C([H])C(OC2=C([H])C3=C(C([H])=C2[H])C([H])([H])C([H])([H])[C@]([H])(N([H])C([H])([H])[C@]([H])(O[H])C2=C([H])C(Cl)=C([H])C([H])=C2[H])C3([H])[H])=C([H])C(=C1[H])N(C([H])([H])[H])C([H])([H])[H]
[H]OC(=O)C1=C([H])C(OC2=C([H])C3=C(C([H])=C2[H])C([H])([H])C([H])([H])[C@]([H])(N([H])C([H])([H])[C@]([H])(O[H])C2=C([H])C(Cl)=C([H])C([H])=C2[H])C3([H])[H])=C([H])C(N([H])C(=O)C([H])([H])[H])=C1[H]
[H]OC(=O)C1=C([H])C(OC2=C([H])C3=C(C([H])=C2[H])C([H])([H])C([H])([H])[C@]([H])(N([H])C([H])([H])[C@]([H])(O[H])C2=C([H])C(Cl)=C([H])C([H])=C2[H])C3([H])[H])=C([H])C(N([H])C([H])([H])C([H])([H])C([H])([H])[H])=C1[H]
[H]OC(=O)C1=C([H])C(OC2=C([H])C3=C(C([H])=C2[H])C([H])([H])C([H])([H])[C@]([H])(N([H])C([H])([H])[C@]([H])(O[H])C2=C([H])C(Cl)=C([H])C([H])=C2[H])C3([H])[H])=C([H])C(N([H])C2([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])=C1[H]
[H]OC(=O)C1=C([H])C(OC2=C([H])C3=C(C([H])=C2[H])C([H])([H])C([H])([H])[C@]([H])(N([H])C([H])([H])[C@]([H])(O[H])C2=C([H])C(Cl)=C([H])C([H])=C2[H])C3([H])[H])=C([H])C(N([H])C2([H])C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])=C1[H]
[H]OC(=O)C1=C([H])C(OC2=C([H])C3=C(C([H])=C2[H])C([H])([H])C([H])([H])[C@]([H])(N([H])C([H])([H])[C@]([H])(O[H])C2=C([H])C([H])=C(Cl)C([H])=C2[H])C3([H])[H])=C([H])C([H])=C1[H]
[H]OC(=O)C1=C([H])C(OC2=C([H])C3=C(C([H])=C2[H])C([H])([H])C([H])([H])[C@]([H])(N([H])C([H])([H])[C@]([H])(O[H])C2=C([H])C([H])=C(Cl)C([H])=C2[H])C3([H])[H])=C([H])C([H])=C1OC([H])([H])[H]
[H]OC(=O)C1=C([H])C(OC2=C([H])C3=C(C([H])=C2[H])C([H])([H])C([H])([H])[C@]([H])(N([H])C([H])([H])[C@]([H])(O[H])C2=C([H])C([H])=C([H])N=C2[H])C3([H])[H])=C([H])C([H])=C1[H]
[H]C1=NN(C(=C1C([H])([H])N1C([H])([H])C([H])([H])[C@@]([H])(C2=C(OC([H])([H])[H])C([H])=C([H])C(OC([H])([H])[H])=C2[H])C1([H])[H])C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1F
[H]OC1=C2N([H])C(=O)C([H])([H])OC2=C(C([H])=C1[H])[C@]([H])(O[H])C([H])([H])N([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(N([H])C(=O)C([H])([H])C([H])([H])C([H])([H])N([H])C(=O)[C@@]([H])(N([H])[H])C([H])([H])C([H])([H])C([H])([H])N([H])[H])C([H])=C1[H]
[H]OC1=C([H])C(=C2OC([H])([H])C(=O)N([H])C2=C1[H])[C@]([H])(O[H])C([H])([H])N([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(N([H])C(=O)C([H])([H])C([H])([H])C([H])([H])N([H])C(=N[H])N([H])[H])C([H])=C1[H]
[H]OC1=C([H])C(=C2OC([H])([H])C(=O)N([H])C2=C1[H])[C@]([H])(O[H])C([H])([H])N([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(N([H])C(=O)C([H])([H])C([H])([H])C([H])([H])N([H])C(=O)C([H])([H])[N+](C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])=C1[H]
[H]OC1=C2N([H])C(=O)SC2=C(C([H])=C1[H])[C@@]([H])(O[H])C([H])([H])N([H])[C@]1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])OC([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC1=C2N([H])C(=O)SC2=C(C([H])=C1[H])C([H])(O[H])C([H])([H])N([H])C1([H])C([H])([H])C2([H])C([H])([H])C([H])([H])C1(C([H])([H])[H])C2(C([H])([H])[H])C([H])([H])[H]
[H]OC1=C2N([H])C(=O)SC2=C(C([H])=C1[H])[C@@]([H])(O[H])C([H])([H])N([H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])N2C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]N(C1=NC([H])=C([H])C(=C1[H])C1=NC(N2C([H])([H])C([H])([H])N([H])C([H])([H])C2([H])[H])=C2C([H])=C([H])N=C([H])C2=C1[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]OC1=C2N([H])C(=O)SC2=C(C([H])=C1[H])[C@@]([H])(O[H])C([H])([H])N([H])C([H])([H])C([H])([H])OC1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC1=C2N([H])C(=O)SC2=C(C([H])=C1[H])[C@@]([H])(O[H])C([H])([H])N([H])C([H])([H])C([H])([H])C([H])([H])N(C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H]
[H]OC1=C2N([H])C(=O)SC2=C(C([H])=C1[H])[C@@]([H])(O[H])C([H])([H])N([H])[C@]([H])(C(=O)N([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC1=C2N([H])C(=O)SC2=C(C([H])=C1[H])[C@@]([H])(O[H])C([H])([H])N([H])C([H])([H])C([H])([H])SC1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]OC1=C2N([H])C(=O)SC2=C(C([H])=C1[H])[C@@]([H])(O[H])C([H])([H])N([H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]OC1=C2N([H])C(=O)C([H])=C([H])C2=C(C([H])=C1[H])[C@@]([H])(O[H])C([H])([H])N([H])C1([H])C([H])([H])C2=C(C([H])=C(C(=C2[H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H])C1([H])[H]
[H]OC1=C2N([H])C(=O)SC2=C(C([H])=C1[H])[C@@]([H])(O[H])C([H])([H])N([H])C([H])([H])C([H])(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H]
[H]OC1=C2N([H])C(=O)SC2=C(C([H])=C1[H])[C@@]([H])(O[H])C([H])([H])N([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]OC1=C2N([H])C(=O)SC2=C(C([H])=C1[H])[C@@]([H])(O[H])C([H])([H])N([H])C([H])([H])[C@]12C([H])([H])[C@@]3([H])C([H])([H])[C@]([H])(C([H])([H])[C@]([H])(C3([H])[H])C1([H])[H])C2([H])[H]
[H]OC1=C2N([H])C(=O)SC2=C(C([H])=C1[H])[C@@]([H])(O[H])C([H])([H])N([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC1=C2N([H])C(=O)SC2=C(C([H])=C1[H])[C@@]([H])(O[H])C([H])([H])N([H])C([H])([H])C1=C(ON=C1C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H]
[H]OC1=C2N([H])C(=O)SC2=C(C([H])=C1[H])[C@@]([H])(O[H])C([H])([H])N([H])C([H])([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC1=C2N([H])C(=O)SC2=C(C([H])=C1[H])[C@@]([H])(O[H])C([H])([H])N([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC1=C2N([H])C(=O)SC2=C(C([H])=C1[H])[C@@]([H])(O[H])C([H])([H])N([H])[C@@]1([H])C2=C(C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C1([H])[H]
[H]OC1=C2N([H])C(=O)SC2=C(C([H])=C1[H])[C@@]([H])(O[H])C([H])([H])N([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC1=C2N([H])C(=O)SC2=C(C([H])=C1[H])[C@@]([H])(O[H])C([H])([H])N([H])[C@@]([H])(C1=C([H])C([H])=C2C([H])=C([H])C([H])=C([H])C2=C1[H])C([H])([H])[H]
[H]OC1=C2N([H])C(=O)SC2=C(C([H])=C1[H])[C@@]([H])(O[H])C([H])([H])N([H])[C@]1([H])C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])OC([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N([H])C(=O)C1=C([H])C(=NC(=C1[H])C1=C([H])C(=NC([H])=C1[H])N([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])N1C([H])([H])C([H])([H])N([H])C([H])([H])C1([H])[H]
[H]N([H])N1C(=O)C2=C(N=C1C([H])([H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C3=NC4=C([H])C([H])=C([H])C([H])=C4C([H])=C3[H])C([H])([H])C1([H])[H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H]
OCC1=CC(OCC(O)CNC2CCN(CC2)C2=NC=NC3=C2C(=CS3)C2=CC=CS2)=CC=C1O
OC(CNC1CCN(CC1)C1=NC=NC2=C1C(=CS2)C1=CC=CS1)COC1=CC=C(O)C=C1
OC(CNC1CCN(CC1)C1=NC=NC2=C1C(=CS2)C1=CC=CS1)COC1=CC=CC=C1
OC(CNC1CCN(CC1)C1=NC=NC2=C1C(=CS2)C1=CC=C(F)C=C1)COC1=CC=C(O)C=C1
OC(CNC1CCN(CC1)C1=NC=NC2=C1C(=CS2)C1=CC=C(F)C=C1)COC1=CC=CC=C1
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[H]O[C@]([H])(C([H])([H])OC1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])N([H])C([H])([H])C([H])([H])OC1=C([H])C([H])=C(C([H])=C1[H])N1C([H])=NC([H])=C1[H]
[H]O[C@]([H])(C([H])([H])OC1=C(C([H])=C([H])C([H])=C1[H])C([H])([H])[H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C([H])C([H])=C(N([H])S(=O)(=O)C([H])([H])[H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]O[C@]([H])(C1=C([H])C([H])=C(N([H])S(=O)(=O)C([H])([H])[H])C([H])=C1[H])C([H])([H])N([H])C([H])([H])C([H])([H])OC1=C([H])C([H])=C(C([H])=C1[H])N1C([H])=NC([H])=C1[H]
[H]OC(=O)C1=C([H])C([H])=C(C([H])=C1S(=O)(=O)C([H])(C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])N([H])C([H])([H])[C@]([H])(O[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC(=O)C1=C([H])C([H])=C(C([H])=C1OC1([H])C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])N([H])C([H])([H])[C@]([H])(O[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
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[H]OC(=O)C1=C([H])C([H])=C(C([H])=C1[H])C1=C(Cl)C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])N([H])C([H])([H])[C@]([H])(O[H])C1=C([H])C(Cl)=C([H])C([H])=C1[H]
[H]OC(=O)C1=C([H])C([H])=C(C(OC([H])([H])[H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])N([H])C([H])([H])[C@]([H])(O[H])C1=C([H])C(Cl)=C([H])C([H])=C1[H]
[H]OC(=O)C1=C([H])C([H])=C(C(F)=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])N([H])C([H])([H])[C@]([H])(O[H])C1=C([H])C(Cl)=C([H])C([H])=C1[H]
[H]OC(=O)C1=C([H])C([H])=C(C2=C([H])C([H])=C(C([H])=C2[H])C([H])([H])C([H])([H])N([H])C([H])([H])[C@]([H])(O[H])C2=C([H])C(Cl)=C([H])C([H])=C2[H])C(=C1[H])C([H])([H])[H]
[H]OC(=O)C1=C([H])C([H])=C(C([H])=C1F)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])N([H])C([H])([H])[C@]([H])(O[H])C1=C([H])C(Cl)=C([H])C([H])=C1[H]
[H]OC(=O)C1=C([H])C([H])=C(C([H])=C1C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])N([H])C([H])([H])[C@]([H])(O[H])C1=C([H])C(Cl)=C([H])C([H])=C1[H]
[H]OC(=O)C1=C([H])C([H])=C(OC2=C([H])C([H])=C(C([H])=C2[H])C([H])([H])C([H])([H])N([H])C([H])([H])[C@]([H])(O[H])C2=C([H])C(Cl)=C([H])C([H])=C2[H])N=C1[H]
[H]OC(=O)C1=C([H])C([H])=C(S1)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])N([H])C([H])([H])[C@]([H])(O[H])C1=C([H])C(Cl)=C([H])C([H])=C1[H]
[H]OC(=O)C1=C([H])C([H])=C(N=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])N([H])C([H])([H])[C@]([H])(O[H])C1=C([H])C(Cl)=C([H])C([H])=C1[H]
[H]OC(=O)C1=C([H])C(N([H])C2=C([H])C([H])=C(C([H])=C2[H])C([H])([H])C([H])([H])N([H])C([H])([H])[C@]([H])(O[H])C2=C([H])C(Cl)=C([H])C([H])=C2[H])=C([H])C([H])=C1[H]
[H]OC(=O)C1=C([H])C([H])=C(N([H])C2=C([H])C([H])=C(C([H])=C2[H])C([H])([H])C([H])([H])N([H])C([H])([H])[C@]([H])(O[H])C2=C([H])C(Cl)=C([H])C([H])=C2[H])C([H])=C1[H]
[H]OC(=O)C1=C([H])C(=C([H])C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])N([H])C([H])([H])[C@]([H])(O[H])C1=C([H])C(Cl)=C([H])C([H])=C1[H]
[H]OC(=O)C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])N([H])C([H])([H])[C@]([H])(O[H])C1=C([H])C(Cl)=C([H])C([H])=C1[H]
[H]OC(=O)C([H])([H])OC1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])N([H])C([H])([H])[C@]([H])(O[H])C1=C([H])C(Cl)=C([H])C([H])=C1[H]
[H]OC(=O)C([H])([H])OC1=C([H])C([H])=C(C([H])=C1[H])C(=O)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])N([H])C([H])([H])[C@]([H])(O[H])C1=C([H])C(Cl)=C([H])C([H])=C1[H]
[H]OC(=O)C([H])([H])OC1=C([H])C([H])=C(SC2=C([H])C([H])=C(C([H])=C2[H])C([H])([H])C([H])([H])N([H])C([H])([H])[C@]([H])(O[H])C2=C([H])C(Cl)=C([H])C([H])=C2[H])C([H])=C1[H]
[H]OC(=O)C([H])([H])OC1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])N([H])C([H])([H])[C@]([H])(O[H])C1=C([H])C(Cl)=C([H])C([H])=C1[H]
[H]OC(=O)C([H])([H])OC1=C([H])C([H])=C(C([H])=C1[H])N(C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])N([H])C([H])([H])[C@]([H])(O[H])C1=C([H])C(Cl)=C([H])C([H])=C1[H])C([H])([H])[H]
[H]OC(=O)C([H])([H])OC1=C([H])C([H])=C(N([H])C2=C([H])C([H])=C(C([H])=C2[H])C([H])([H])C([H])([H])N([H])C([H])([H])[C@]([H])(O[H])C2=C([H])C(Cl)=C([H])C([H])=C2[H])C([H])=C1[H]
[H]OC(=O)C([H])([H])OC1=C([H])C([H])=C(OC2=C([H])C([H])=C(C([H])=C2[H])C([H])([H])C([H])([H])N([H])C([H])([H])[C@]([H])(O[H])C2=C([H])C(Cl)=C([H])C([H])=C2[H])C([H])=C1[H]
[H]OC(=O)C1=C([H])C([H])=C(C([H])=C1C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])N([H])C([H])([H])[C@]([H])(O[H])C1=C([H])C(Cl)=C([H])C([H])=C1[H]
[H]OC(=O)C1=C([H])C([H])=C(C([H])=C1Cl)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])N([H])C([H])([H])[C@]([H])(O[H])C1=C([H])C(Cl)=C([H])C([H])=C1[H]
[H]OC(=O)C([H])([H])OC1=C([H])C([H])=C(OC2=C([H])C3=C(C([H])=C2[H])C([H])([H])C([H])([H])[C@]([H])(N([H])C([H])([H])[C@]([H])(O[H])C2=C([H])C(Cl)=C([H])C([H])=C2[H])C3([H])[H])C([H])=C1[H]
[H]OC([H])([H])[C@@]([H])(N([H])C([H])([H])[C@]([H])(O[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C(C(=O)N([H])S(=O)(=O)C([H])([H])[H])C(OC2([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])=C1[H]
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[H]OC1=C(C([H])=C(C([H])=C1[H])[C@@]([H])(O[H])C([H])([H])N([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])OC([H])([H])C([H])([H])C([H])([H])C([H])([H])C1=C([H])C(=C([H])C([H])=C1[H])N1C(=O)N([H])C(C1=O)(C([H])([H])[H])C([H])([H])[H])C([H])([H])O[H]
[H]OC1=C(C([H])=C(C([H])=C1[H])[C@@]([H])(O[H])C([H])([H])N([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])OC([H])([H])C([H])([H])C([H])([H])C([H])([H])C1=C([H])C(=C([H])C([H])=C1[H])N1C(=O)N([H])C(=O)C1([H])[H])C([H])([H])O[H]
[H]OC1=C(C([H])=C(C([H])=C1[H])[C@@]([H])(O[H])C([H])([H])N([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])OC([H])([H])C([H])([H])C([H])([H])C([H])([H])C1=C([H])C(=C([H])C([H])=C1[H])C([H])([H])N1C(=O)N([H])C(=O)C1=O)C([H])([H])O[H]
[H]O[C@]([H])(C([H])([H])OC1=C(C#N)C([H])=C([H])C([H])=C1[H])C([H])([H])N([H])C([H])([H])C([H])([H])N([H])C(=O)N([H])C1=C([H])C([H])=C([H])C([H])=C1F
[H]O[C@]([H])(C([H])([H])OC1=C(C#N)C([H])=C([H])C([H])=C1[H])C([H])([H])N([H])C([H])([H])C([H])([H])N([H])C(=O)N([H])C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]O[C@]([H])(C([H])([H])OC1=C(C#N)C([H])=C([H])C([H])=C1[H])C([H])([H])N([H])C([H])([H])C([H])([H])N([H])C(=O)N([H])C1=C([H])C([H])=C(OC([H])([H])C([H])([H])F)C([H])=C1[H]
[H]O[C@]([H])(C([H])([H])OC1=C(C#N)C([H])=C([H])C([H])=C1[H])C([H])([H])N([H])C([H])([H])C([H])([H])N([H])C(=O)N([H])C1=C([H])C([H])=C(OC([H])([H])C([H])([H])C([H])([H])F)C([H])=C1[H]
[H]O[C@]([H])(C([H])([H])OC1=C(C#N)C([H])=C([H])C([H])=C1[H])C([H])([H])N([H])C([H])([H])C([H])([H])N([H])C(=O)N([H])C1=C([H])C([H])=C([H])C(OC([H])([H])C([H])([H])F)=C1[H]
[H]O[C@]([H])(C([H])([H])OC1=C(C#N)C([H])=C([H])C([H])=C1[H])C([H])([H])N([H])C([H])([H])C([H])([H])N([H])C(=O)N([H])C1=C([H])C([H])=C(N([H])[C@]([H])(C([H])([H])[H])C([H])([H])F)C([H])=C1[H]
[H]OC(=O)C1=C([H])C([H])=C(N([H])C(=O)N([H])C([H])([H])C([H])([H])N([H])C([H])([H])[C@]([H])(O[H])C([H])([H])OC2=C(C#N)C(F)=C([H])C([H])=C2[H])C([H])=C1[H]
[H]OC(=O)C1=C([H])C([H])=C(N([H])C(=O)N([H])C([H])([H])C([H])([H])N([H])C([H])([H])[C@]([H])(O[H])C([H])([H])OC2=C(C#N)C([H])=C([H])C(F)=C2[H])C([H])=C1[H]
[H]OC(=O)C1=C([H])C([H])=C(N([H])C(=O)N([H])C([H])([H])C([H])([H])N([H])C([H])([H])[C@]([H])(O[H])C([H])([H])OC2=C(C#N)C([H])=C([H])C([H])=C2[H])C([H])=C1F
[H]O[C@]([H])(C([H])([H])OC1=C(C#N)C(F)=C([H])C([H])=C1[H])C([H])([H])N([H])C([H])([H])C([H])([H])N([H])C(=O)N([H])C1=C([H])C([H])=C(OC([H])([H])C([H])([H])[H])C([H])=C1[H]
[H]O[C@]([H])(C([H])([H])OC1=C(C#N)C([H])=C([H])C([H])=C1[H])C([H])([H])N([H])C([H])([H])C([H])([H])N([H])C(=O)N([H])C1=C([H])N=C(OC([H])([H])C([H])([H])F)C([H])=C1[H]
[H]O[C@]([H])(C([H])([H])OC1=C(C#N)C([H])=C([H])C([H])=C1[H])C([H])([H])N([H])C([H])([H])C([H])([H])N([H])C(=O)N([H])C1=C([H])N=C(F)C([H])=C1[H]
[H]O[C@]([H])(C([H])([H])OC1=C(C#N)C([H])=C([H])C([H])=C1[H])C([H])([H])N([H])C([H])([H])C([H])([H])N([H])C(=O)N([H])C1=C([H])N=C(I)C([H])=C1[H]
[H]O[C@]([H])(C([H])([H])OC1=C(C#N)C([H])=C([H])C([H])=C1[H])C([H])([H])N([H])C([H])([H])C([H])([H])N([H])C(=O)N([H])C1=C([H])N=C(Br)C([H])=N1
[H]O[C@]([H])(C([H])([H])OC1=C(C#N)C([H])=C([H])C([H])=C1[H])C([H])([H])N([H])C([H])([H])C([H])([H])N([H])C(=O)N([H])C1=NC([H])=C([H])S1
[H]O[C@]([H])(C([H])([H])OC1=C(C#N)C([H])=C([H])C([H])=C1[H])C([H])([H])N([H])C([H])([H])C([H])([H])N([H])C(=O)N([H])C1=NN(N=N1)C([H])([H])C([H])([H])F
[H]O[C@]([H])(C([H])([H])OC1=C(C#N)C([H])=C([H])C([H])=C1[H])C([H])([H])N([H])C([H])([H])C([H])([H])N([H])C(=O)N([H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])F)C([H])([H])C1([H])[H]
[H]O[C@]([H])(C([H])([H])OC1=C(C#N)C([H])=C([H])C([H])=C1[H])C([H])([H])N([H])C([H])([H])C([H])([H])N([H])C(=O)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]O[C@]([H])(C([H])([H])OC1=C(C#N)C([H])=C([H])C([H])=C1[H])C([H])([H])N([H])C([H])([H])C([H])([H])N([H])C(=O)C1=C([H])N=C(F)C([H])=C1[H]
[H]O[C@]([H])(C([H])([H])OC1=C(C#N)C([H])=C([H])C([H])=C1[H])C([H])([H])N([H])C([H])([H])C([H])([H])C([H])([H])C(=O)N([H])C1=C([H])N=C(F)C([H])=C1[H]
[H]O[C@]([H])(C([H])([H])OC1=C(C#N)C([H])=C([H])C([H])=C1[H])C([H])([H])N([H])C([H])([H])C([H])([H])N([H])C(=O)C([H])([H])C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]O[C@]([H])(C([H])([H])OC1=C(C#N)C([H])=C([H])C([H])=C1[H])C([H])([H])N([H])C([H])([H])C([H])([H])N([H])S(=O)(=O)C1=C(F)C([H])=C([H])C([H])=C1[H]
[H]O[C@]([H])(C([H])([H])OC1=C(C#N)C([H])=C([H])C([H])=C1[H])C([H])([H])N([H])C([H])([H])C([H])([H])N([H])C(=O)N([H])C1=C([H])N=C(Br)C([H])=C1[H]
[H]O[C@]([H])(C([H])([H])OC1=C(C#N)C([H])=C([H])C([H])=C1[H])C([H])([H])N([H])C([H])([H])C([H])([H])N([H])C(=O)N([H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]O[C@]([H])(C([H])([H])OC1=C([H])C([H])=C([H])C2=C1C1=C(N2[H])C([H])=C([H])C([H])=C1[H])C([H])([H])N([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(OC2=NC([H])=C(C([H])=C2[H])C(=O)N([H])[H])C([H])=C1[H]
[H]O[C@@]([H])(C([H])([H])OC1=C([H])C([H])=C(C([H])=C1[H])C(=O)OC([H])([H])C([H])([H])[H])C([H])([H])N([H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]O[C@@]([H])(C([H])([H])OC1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])N([H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])C(=C([H])C([H])=C1C(=O)N1C2=C(C([H])=C3OC([H])([H])C4(C3=C2[H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C4([H])[H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C(C([H])=C1C([H])([H])[H])C1=NOC(=N1)C([H])([H])[H]
[H]OC1=C(C([H])=C(C([H])=C1[H])[C@@]([H])(O[H])C([H])([H])N([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])OC([H])([H])C([H])([H])C([H])([H])C([H])([H])C1=C([H])C(N([H])C(=O)N([H])C([H])([H])C([H])([H])[H])=C([H])C([H])=C1[H])C([H])([H])O[H]
[H]OC1=C(C([H])=C(C([H])=C1[H])[C@@]([H])(O[H])C([H])([H])N([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])OC([H])([H])C([H])([H])C([H])([H])C([H])([H])C1=C([H])C(N([H])C(=O)N([H])[H])=C([H])C([H])=C1[H])C([H])([H])O[H]
[H]OC1=C(C([H])=C(C([H])=C1[H])[C@@]([H])(O[H])C([H])([H])N([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])OC([H])([H])C([H])([H])C([H])([H])C([H])([H])C1=C([H])C(N([H])C(=O)N([H])C2([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])=C([H])C([H])=C1[H])C([H])([H])O[H]
[H]OC1=C(C([H])=C(C([H])=C1[H])[C@@]([H])(O[H])C([H])([H])N([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])OC([H])([H])C([H])([H])C([H])([H])C([H])([H])C1=C([H])C(N([H])C(=O)N([H])C([H])([H])C(=O)N([H])C2([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])=C([H])C([H])=C1[H])C([H])([H])O[H]
CCC1=CC2=C(CC(C2)NC[C@H](O)C2=C3CCC(=O)NC3=C(O)C=C2)C=C1CC
CCC1=CC2=C(CC(C2)NCCC2=C3C=CC(=O)NC3=C(O)C=C2)C=C1CC
CCCCC1=CC2=C(CC(C2)NC[C@H](O)C2=C3C=CC(=O)NC3=C(O)C=C2)C=C1
CC1=C(C)C(C)=C(C)C2=C1CC(C2)NC[C@H](O)C1=C2C=CC(=O)NC2=C(O)C=C1
CCC1=CC2=C(CC(C)(C2)NC[C@H](O)C2=C3C=CC(=O)NC3=C(O)C=C2)C=C1CC
CCC1=C(CC)CC2=C(CC(C2)NC[C@H](O)C2=C3C=CC(=O)NC3=C(O)C=C2)C1
CCC1=CC2=C(CC(C2)NCC(O)C2=C3C=C(C)C(=O)NC3=C(O)C=C2)C=C1CC
[H]OC1=C([H])C([H])=C(C([H])=C1C([H])([H])O[H])[C@@]([H])(O[H])C([H])([H])N([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C(N([H])C([H])([H])[C@]([H])(O[H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])=C1[H]
[H]OC1=C([H])C([H])=C(C([H])=C1N([H])C([H])=O)[C@@]([H])(O[H])C([H])([H])N([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C(N([H])C([H])([H])[C@]([H])(O[H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])=C1[H]
[H]OC1=C([H])C([H])=C(C2=C1N([H])C(=O)S2)[C@@]([H])(O[H])C([H])([H])N([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C(=C1[H])C([H])([H])N([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1OC([H])([H])[H]
[H]OC1=C([H])C([H])=C(C2=C1N([H])C(=O)S2)[C@@]([H])(O[H])C([H])([H])N([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C(=C1[H])C([H])([H])N([H])C([H])([H])C([H])([H])C1=C(Cl)C([H])=C([H])C([H])=C1Cl
[H]OC1=C([H])C([H])=C(C2=C1N([H])C(=O)S2)[C@@]([H])(O[H])C([H])([H])N([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N([H])C([H])([H])C([H])([H])C1=C(Cl)C([H])=C([H])C([H])=C1Cl
[H]OC1=C([H])C([H])=C(C2=C1N([H])C(=O)S2)[C@@]([H])(O[H])C([H])([H])N([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C(=C1[H])C([H])([H])N([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1F
[H]OC1=C([H])C([H])=C(C2=C1N([H])C(=O)S2)[C@@]([H])(O[H])C([H])([H])N([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1F
[H]OC1=C([H])C([H])=C(C2=C1N([H])C(=O)S2)[C@@]([H])(O[H])C([H])([H])N([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C(=C1[H])C([H])([H])N([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1OC([H])([H])[H]
[H]OC1=C([H])C([H])=C(C2=C1N([H])C(=O)S2)[C@@]([H])(O[H])C([H])([H])N([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1OC([H])([H])[H]
[H]OC1=C([H])C([H])=C(C2=C1N([H])C(=O)S2)[C@@]([H])(O[H])C([H])([H])N([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C(=C1[H])C([H])([H])N([H])C([H])([H])C([H])([H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2C([H])([H])[H]
[H]OC1=C([H])C([H])=C(C2=C1N([H])C(=O)S2)[C@@]([H])(O[H])C([H])([H])N([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C(=C1[H])C([H])([H])N([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=N1
[H]OC1=C([H])C([H])=C(C2=C1N([H])C(=O)S2)[C@@]([H])(O[H])C([H])([H])N([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=N1
[H]OC1=C([H])C([H])=C(C2=C1N([H])C(=O)S2)[C@@]([H])(O[H])C([H])([H])N([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1C([H])([H])N([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1F
[H]OC1=C([H])C([H])=C(C2=C1N([H])C(=O)S2)[C@@]([H])(O[H])C([H])([H])N([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C(=C1[H])C([H])([H])N([H])C([H])([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC1=C([H])C([H])=C(C2=C1N([H])C(=O)S2)[C@@]([H])(O[H])C([H])([H])N([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C(=C1[H])C([H])([H])N([H])C([H])([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=N1
[H]OC1=C([H])C([H])=C(C2=C1N([H])C(=O)S2)[C@@]([H])(O[H])C([H])([H])N([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N([H])C([H])([H])C1=C(OC([H])([H])[H])C([H])=C([H])C([H])=C1[H]
[H]OC1=C([H])C([H])=C(C2=C1N([H])C(=O)S2)[C@@]([H])(O[H])C([H])([H])N([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C(=C1[H])C([H])([H])N([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1Cl
[H]OC1=C([H])C([H])=C(C2=C1N([H])C(=O)S2)[C@@]([H])(O[H])C([H])([H])N([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C(=C1[H])C([H])([H])N([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=N1
[H]OC1=C([H])C([H])=C(C2=C1N([H])C(=O)S2)[C@@]([H])(O[H])C([H])([H])N([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C(=C1[H])C([H])([H])N([H])C([H])([H])C1=C([H])C([H])=C([H])C(OC([H])([H])[H])=C1[H]
[H]OC1=C([H])C([H])=C(C2=C1N([H])C(=O)S2)[C@@]([H])(O[H])C([H])([H])N([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C(=C1[H])C([H])([H])N([H])C([H])([H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]OC1=C([H])C([H])=C(C2=C1N([H])C(=O)S2)[C@@]([H])(O[H])C([H])([H])N([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C(=C1[H])C([H])([H])N([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1OC([H])([H])C([H])([H])[H]
[H]OC1=C([H])C([H])=C(C2=C1N([H])C(=O)S2)[C@@]([H])(O[H])C([H])([H])N([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C(=C1[H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1OC([H])([H])[H]
[H]OC1=C([H])C([H])=C(C2=C1N([H])C(=O)S2)[C@@]([H])(O[H])C([H])([H])N([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N([H])C([H])([H])C([H])([H])OC([H])([H])[H]
[H]OC1=C([H])C([H])=C(C2=C1N([H])C(=O)S2)[C@@]([H])(O[H])C([H])([H])N([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C(=C1[H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]OC1=C([H])C([H])=C(C2=C1N([H])C(=O)S2)[C@@]([H])(O[H])C([H])([H])N([H])C([H])([H])C([H])([H])C([H])([H])C1=C([H])C(=C([H])C([H])=C1[H])C([H])([H])N([H])C([H])([H])C([H])([H])C1=C(Cl)C([H])=C([H])C([H])=C1Cl
[H]OC1=C([H])C([H])=C(C2=C1N([H])C(=O)S2)[C@@]([H])(O[H])C([H])([H])N([H])C([H])([H])C([H])([H])OC1=C([H])C(=C([H])C([H])=C1[H])C([H])([H])N([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1F
[H]OC1=C([H])C([H])=C(C2=C1N([H])C(=O)S2)[C@@]([H])(O[H])C([H])([H])N([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C(=C1[H])C([H])([H])C([H])([H])N([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1OC([H])([H])[H]
[H]OC1=C([H])C([H])=C(C([H])=C1C([H])([H])O[H])[C@@]([H])(O[H])C([H])([H])N([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC1=C([H])C([H])=C(C2=C1N([H])C(=O)C([H])=C2[H])[C@@]([H])(O[H])C([H])([H])N([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C(=C1[H])C([H])([H])N([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=N1
[H]OC1=C([H])C([H])=C(C2=C1N([H])C(=O)S2)[C@@]([H])(O[H])C([H])([H])N([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N([H])C([H])([H])C([H])([H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2C([H])([H])[H]
[H]OC1=C([H])C([H])=C(C2=C1N([H])C(=O)S2)[C@@]([H])(O[H])C([H])([H])N([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C(=C1[H])C([H])([H])N([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1Cl
[H]OC1=C([H])C([H])=C(C2=C1N([H])C(=O)S2)[C@@]([H])(O[H])C([H])([H])N([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC1=C([H])C([H])=C(C2=C1N([H])C(=O)S2)[C@@]([H])(O[H])C([H])([H])N([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N([H])C([H])([H])[C@@]([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H]
[H]OC1=C([H])C([H])=C(C2=C1N([H])C(=O)S2)[C@@]([H])(O[H])C([H])([H])N([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C(=C1[H])C([H])([H])N([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1F
[H]OC1=C([H])C([H])=C(C2=C1N([H])C(=O)S2)[C@@]([H])(O[H])C([H])([H])N([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C(=C1[H])C([H])([H])N([H])C([H])([H])C([H])([H])OC([H])([H])[H]
[H]OC1=C([H])C([H])=C(C2=C1N([H])C(=O)S2)[C@@]([H])(O[H])C([H])([H])N([H])[C@]([H])(C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C(=C1[H])C([H])([H])N([H])C([H])([H])C([H])([H])C1=C(Cl)C([H])=C([H])C([H])=C1Cl
[H]OC1=C(C([H])=C(C([H])=C1[H])[C@@]([H])(O[H])C([H])([H])N([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])OC([H])([H])C([H])([H])C([H])([H])C([H])([H])C1=C([H])C(=C([H])C([H])=C1[H])C([H])([H])N([H])C(=O)N([H])[H])C([H])([H])O[H]
[H]O[C@]([H])(C1=C([H])C([H])=C([H])C(Cl)=C1[H])C([H])([H])N([H])[C@]([H])(C([H])([H])[H])C([H])([H])N([H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C(=O)N([H])S(=O)(=O)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H]
[H]OC(=O)C([H])([H])C1=C([H])C([H])=C(N([H])C([H])([H])[C@]([H])(N([H])C([H])([H])[C@]([H])(O[H])C2=C([H])C([H])=C([H])C(Cl)=C2[H])C([H])([H])[H])C([H])=C1[H]
[H]O[C@]([H])(C1=C([H])C([H])=C([H])C(Cl)=C1[H])C([H])([H])N([H])[C@]([H])(C([H])([H])[H])C([H])([H])N([H])C1=C([H])C(=C([H])C([H])=C1[H])C([H])([H])C(=O)N([H])S(=O)(=O)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H]
CC1=C2C=CC=CC2=NC(=C1)N1CCNCC1
[H]N1C([H])=C([H])C2=C(C([H])=C([H])C([H])=C12)N1C([H])([H])C([H])([H])N([H])C([H])([H])C1([H])[H]
[H]N1C([H])([H])C([H])([H])N(C2=NC3=C(C([H])=C([H])C([H])=C3[H])C([H])=C2[H])C([H])([H])C1([H])[H]
OC(CNCCOCCOCCNC(=O)CCCCCNC(=O)COC1=CC=C(\C=C\C2=CC=C3C=C4C=CC(C5=CC=CS5)=[N+]4[B-](F)(F)N23)C=C1)COC1=CC=CC=C1CC=C
OC(CNCCNC(=O)CCCCCNC(=O)COC1=CC=C(\C=C\C2=CC=C3C=C4C=CC(C5=CC=CS5)=[N+]4[B-](F)(F)N23)C=C1)COC1=CC=CC=C1CC=C
OC(CNCCOCCOCCNC(=O)CCCCCNC(=O)COC1=CC=C(\C=C\C2=CC=C3C=C4C=CC(C5=CC=CS5)=[N+]4[B-](F)(F)N23)C=C1)COC1=CC=CC2=C1C=CC=C2
O[C@@H](CNCCCCNC(=O)CCCCCNC(=O)COC1=CC=C(\C=C\C2=CC=C3C=C4C=CC(C5=CC=CS5)=[N+]4[B-](F)(F)N23)C=C1)COC1=CC=CC2=C1C=CC=C2
O[C@@H](CNCCCCCCCCNC(=O)CCCCCNC(=O)COC1=CC=C(\C=C\C2=CC=C3C=C4C=CC(C5=CC=CS5)=[N+]4[B-](F)(F)N23)C=C1)COC1=CC=CC2=C1C=CC=C2
OC(CNCCNC(=O)CCCCCNC(=O)COC1=CC=C(\C=C\C2=CC=C3C=C4C=CC(C5=CC=CS5)=[N+]4[B-](F)(F)N23)C=C1)COC1=CC=CC2=C1C=CC=C2
OC(CNCCOCCOCCNC(=O)CCCCCNC(=O)COC1=CC=C(\C=C\C2=CC=C3C=C4C=CC(C5=CC=CS5)=[N+]4[B-](F)(F)N23)C=C1)COC1=CC=CC2=C1C=CN2
OC(CNCCNC(=O)CCCCCNC(=O)COC1=CC=C(\C=C\C2=CC=C3C=C4C=CC(C5=CC=CS5)=[N+]4[B-](F)(F)N23)C=C1)COC1=CC=CC2=C1C=CN2
[H][C@]12C[C@H](CN(C)[C@]1([H])CC1=CC=CC(OC)=C1C2)C(=O)N1CCN(CC1)C1=CC=C(C=C1)[N+]([O-])=O