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[H]C1=NC([H])=C(O1)C1=C([H])C([H])=C(OC([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])=C1[H]
[H]C1=NC([H])=C([H])C(=C1[H])C1=C([H])C([H])=C(OC([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])=C1[H]
[H]C1=C([H])N=C(C([H])=N1)C1=C([H])C([H])=C(OC([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])=C1[H]
[H]C1=NC(=C([H])N1C1=C([H])C([H])=C(OC([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])=C1[H])C([H])([H])[H]
[H]C1=C([H])N(C([H])=N1)C1=C([H])C([H])=C(OC([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])=C1[H]
[H]N1C([H])=NC(=C1[H])C1=C([H])C([H])=C(OC([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])=C1[H]
[H]C1=NN(C([H])=N1)C1=C([H])C([H])=C(OC([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])=C1[H]
[H]OC1=C([H])C([H])=C(N([H])C2=C([H])C([H])=NC3=C([H])C(Cl)=C([H])C([H])=C23)C([H])=C1C([H])([H])N([H])C([H])([H])C([H])([H])[H]
[H]C1=NC([H])=C(N1C1=C([H])C([H])=C(OC([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])=C1[H])C([H])([H])[H]
[H]C1=NC(=C([H])C([H])=N1)C1=C([H])C([H])=C(OC([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])=C1[H]
[H]C1=C([H])N(C([H])=N1)C1=C([H])C([H])=C(OC([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H])C([H])=C1[H]
[H]C1=C([H])N(C([H])=N1)C1=C([H])C([H])=C(OC([H])([H])C([H])([H])C([H])([H])C2=C([H])C([H])=C([H])N=C2[H])C([H])=C1[H]
[H]C1=C([H])N(C([H])=N1)C1=C([H])C([H])=C(OC([H])([H])C([H])([H])N2C([H])([H])C([H])([H])N(C(=O)OC([H])([H])C([H])([H])[H])C([H])([H])C2([H])[H])C([H])=C1[H]
[H]C1=C([H])N(C([H])=N1)C1=C([H])C([H])=C(OC([H])([H])C([H])([H])N2C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])C([H])=C1[H]
[H]C1=C([H])N(C([H])=N1)C1=C([H])C([H])=C(OC([H])([H])C([H])([H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=N2)C([H])=C1[H]
[H]C1=C([H])N(C([H])=N1)C1=C([H])C([H])=C(OC([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])N=C1[H]
[H]C1=C([H])N(C([H])=N1)C1=C([H])C([H])=C(OC([H])([H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H])C([H])=C1[H]
[H]C1=C([H])N(C([H])=N1)C1=C([H])C([H])=C(OC([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H])C([H])=C1[H]
[H]C1=C([H])N(C([H])=N1)C1=C([H])C([H])=C(OC([H])([H])C([H])([H])C([H])([H])C2=C([H])C([H])=NC([H])=C2[H])C([H])=C1[H]
[H]C1=C([H])N(C([H])=N1)C1=C([H])C([H])=C(OC([H])([H])C2=C([H])C([H])=C([H])C([H])=N2)C([H])=C1[H]
[H]O[C@]([H])(C([H])([H])OC1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])N1C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])[C@]([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C(F)(F)F
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[H]O[C@]([H])(C([H])([H])OC1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])C([H])([H])N1C([H])([H])C([H])([H])C([H])(N(C(=O)C2=C([H])C([H])=C(Cl)C([H])=C2[H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
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[H]O[C@]([H])(C([H])([H])OC1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])C([H])([H])N1C([H])([H])C([H])([H])C([H])(N(C(=O)C2=C([H])C([H])=C(OC([H])([H])[H])C([H])=C2[H])C2=C([H])C([H])=C(F)C([H])=C2[H])C([H])([H])C1([H])[H]
[H]O[C@]([H])(C([H])([H])OC1=C(C([H])=C([H])C([H])=C1C([H])([H])[H])C([H])([H])[H])C([H])([H])N1C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])[C@@]([H])(C(=O)N([H])C([H])([H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H]
[H]O[C@]([H])(C([H])([H])OC1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])C([H])([H])N1C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])[C@@]([H])(C(=O)N([H])C([H])([H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C(F)(F)F
[H]O[C@]([H])(C([H])([H])OC1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])C([H])([H])N1C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])[C@@]([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])N([H])C(=O)C1=C([H])C([H])=C([H])C([H])=C1OC([H])([H])[H]
[H]O[C@]([H])(C([H])([H])OC1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])C([H])([H])N1C([H])([H])C([H])([H])C([H])(N(C(=O)C2=C([H])C([H])=C(Cl)C([H])=C2[H])C2=C([H])C([H])=C(F)C([H])=C2[H])C([H])([H])C1([H])[H]
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[H]O[C@]([H])(C([H])([H])OC1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])C([H])([H])N1C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])[C@@]([H])(C(=O)N([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C(F)(F)F
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[H]O[C@]([H])(C([H])([H])OC1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])C([H])([H])N1C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])[C@@]([H])(C(=O)N([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]O[C@]([H])(C([H])([H])OC1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])C([H])([H])N1C([H])([H])C([H])([H])C([H])(N(C(=O)C2=C([H])C([H])=C(OC([H])([H])[H])C([H])=C2[H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
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[H]O[C@]1([H])C([H])([H])N(C([H])([H])[C@@]([H])(N(C(=O)C([H])([H])N([H])C2=C([H])C([H])=C(C([H])=C2[H])C([H])([H])N([H])S(=O)(=O)C([H])([H])[H])C([H])([H])[H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]O[C@]1([H])C([H])([H])N(C([H])([H])[C@@]([H])(N(C(=O)C([H])([H])N(C2=C([H])C([H])=C(C#N)C([H])=C2[H])C([H])([H])[H])C([H])([H])[H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]O[C@]1([H])C([H])([H])N(C([H])([H])[C@@]([H])(N(C(=O)C([H])([H])N([H])C2=C([H])C([H])=C(C([H])=C2[H])C(F)(F)F)C([H])([H])[H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]O[C@]1([H])C([H])([H])N(C([H])([H])[C@@]([H])(N(C(=O)C([H])([H])N([H])C2=C([H])C([H])=C([H])C(=C2[H])C([H])([H])N([H])S(=O)(=O)C([H])([H])[H])C([H])([H])[H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
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[H]N1C([H])=NC(=C1[H])C([H])([H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])OC2=NC([H])=C(C([H])=C2[H])C(=O)N2C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]N(C(=O)C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])(C([H])([H])C2=C([H])N([H])C([H])=N2)C([H])([H])C1([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N1C([H])=NC(=C1[H])C([H])([H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])OC2=C([H])C([H])=C(C([H])=C2[H])C([H])([H])N2C(=O)C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]N1C([H])=NC(=C1[H])C([H])([H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])OC2=C([H])C([H])=C(N=C2[H])C([H])([H])N2C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]N1C([H])=NC(=C1[H])C([H])([H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])OC2=C([H])C([H])=C(C([H])=C2[H])C([H])([H])N2C([H])([H])C([H])([H])C(F)(F)C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]N1C([H])=NC(=C1[H])C([H])([H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])OC2=C([H])C([H])=C([H])C(=C2[H])C([H])([H])N2C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]N1C([H])=NC(=C1[H])C([H])([H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])OC2=C([H])C([H])=C(C([H])=C2[H])C([H])([H])N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N(C1=C([H])C([H])=C(OC([H])([H])C([H])([H])C([H])([H])N2C([H])([H])C([H])([H])C([H])(C([H])([H])C3=C([H])N([H])C([H])=N3)C([H])([H])C2([H])[H])C([H])=C1[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N1C([H])=NC(=C1[H])C([H])([H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])OC2=C([H])C([H])=C3N=C([H])C([H])=C([H])C3=C2[H])C([H])([H])C1([H])[H]
[H]N(C(=O)N1C([H])([H])C([H])([H])C([H])(C([H])([H])C2=C([H])N([H])C([H])=N2)C([H])([H])C1([H])[H])C1=NC([H])=C([H])C([H])=N1
[H]N1C([H])=NC(=C1[H])C([H])([H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])OC2=C([H])C([H])=C(C([H])=C2[H])C(=O)N2C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]N1C([H])=NC(=C1[H])C([H])([H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])OC2=C([H])C([H])=C(C([H])=C2[H])C([H])([H])N2C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]N(C(=O)N1C([H])([H])C([H])([H])C([H])(C([H])([H])C2=C([H])N([H])C([H])=N2)C([H])([H])C1([H])[H])C1=NC([H])=C([H])S1
[H]N1C([H])=NC(=C1[H])C([H])([H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])OC2=C([H])C([H])=C(C([H])=C2[H])C2=C([H])N=C([H])N=C2[H])C([H])([H])C1([H])[H]
[H]N1C([H])=NC(=C1[H])C([H])([H])C1([H])C([H])([H])C([H])([H])N(C(=O)C([H])([H])C([H])([H])C2=C([H])C([H])=C(C([H])=C2[H])C([H])([H])N2C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]N1C([H])=NC(=C1[H])C([H])([H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])OC2=C([H])C([H])=C(C([H])=C2[H])N2C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]N1C([H])=NC(=C1[H])C([H])([H])C1([H])C([H])([H])C([H])([H])N(C(=O)C([H])([H])C([H])([H])OC2=C([H])C([H])=C(C([H])=C2[H])C([H])([H])N2C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]N1C([H])=NC(=C1[H])C([H])([H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])OC2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N1C([H])=NC(=C1[H])C([H])([H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])OC2=C([H])C([H])=C(C([H])=C2[H])C2=NC([H])=C([H])C([H])=N2)C([H])([H])C1([H])[H]
[H]N1C([H])=NC(=C1[H])C([H])([H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])OC2=C([H])C(OC3([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C3([H])[H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N1C([H])=NC(=C1[H])C([H])([H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])OC2=C([H])C([H])=C(C([H])=C2[H])C([H])([H])C([H])([H])N2C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]N1C([H])=NC(=C1[H])C([H])([H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])OC2=C([H])C([H])=C(C([H])=C2[H])C2=C([H])C([H])=C([H])N=C2[H])C([H])([H])C1([H])[H]
[H]N1C([H])=NC(=C1[H])C([H])([H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])OC2=C([H])C([H])=C(OC3([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C3([H])[H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]C1=C(Br)SC(=C1[H])N1C(=O)O[C@]2(C1([H])[H])C([H])([H])[N@]1C([H])([H])C([H])([H])[C@]2([H])C([H])([H])C1([H])[H]
[H]N(C(=O)C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])(C([H])([H])C2=C([H])N([H])C([H])=N2)C([H])([H])C1([H])[H])C1=C([H])C(F)=C([H])C([H])=C1[H]
[H]N1C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])[C@@]([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C(Cl)C([H])=C([H])C([H])=C1[H]
[H]C1=C([H])C(=C([H])C([H])=C1C([H])([H])C(=O)N(C([H])([H])C([H])([H])[H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])[C@]([H])(C2=C([H])C([H])=C(C([H])=C2[H])S(=O)(=O)C([H])([H])[H])C2=C([H])C(F)=C([H])C(F)=C2[H])C([H])([H])C1([H])[H])S(=O)(=O)C([H])([H])[H]
[H]N([C@@]1([H])C([H])([H])N(C(=O)N2C([H])([H])C([H])([H])[C@]([H])(N(C(=O)C3=C([H])C([H])=C(S3)C3=C([H])C([H])=C(C([H])=C3[H])C([H])([H])C([H])([H])[H])C([H])([H])[H])C2([H])[H])C([H])([H])C1([H])[H])C1([H])C([H])([H])C([H])([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N([C@@]1([H])C([H])([H])N(C(=O)N2C([H])([H])C([H])([H])[C@]([H])(N(C(=O)C3=C([H])C([H])=C(S3)C3=C(C([H])=C(OC([H])([H])[H])C([H])=C3[H])C([H])([H])[H])C([H])([H])[H])C2([H])[H])C([H])([H])C1([H])[H])C1([H])C([H])([H])C([H])([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N([C@@]1([H])C([H])([H])N(C(=O)N2C([H])([H])C([H])([H])[C@]([H])(N(C(=O)C3=C([H])C([H])=C(S3)C3=C([H])C([H])=C(C([H])=C3[H])C([H])([H])[H])C([H])([H])[H])C2([H])[H])C([H])([H])C1([H])[H])C1([H])C([H])([H])C([H])([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N([C@@]1([H])C([H])([H])N(C(=O)N2C([H])([H])C([H])([H])[C@]([H])(N(C(=O)C3=C([H])C([H])=C(S3)C3=C([H])C([H])=C(C([H])=C3[H])C(F)(F)F)C([H])([H])[H])C2([H])[H])C([H])([H])C1([H])[H])C1([H])C([H])([H])C([H])([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C1([H])[H]
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[H]N([C@@]1([H])C([H])([H])N(C(=O)N2C([H])([H])C([H])([H])[C@]([H])(N(C(=O)C3=C([H])C([H])=C(S3)C3=C([H])C([H])=C(C([H])=C3[H])C([H])([H])C([H])([H])[H])C([H])([H])[H])C2([H])[H])C([H])([H])C1([H])[H])C1([H])C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
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[H]N([C@@]1([H])C([H])([H])N(C(=O)N2C([H])([H])C([H])([H])[C@]([H])(N(C(=O)C3=C([H])C([H])=C(S3)C3=C([H])C([H])=C(C([H])=C3[H])C([H])([H])C([H])([H])[H])C([H])([H])[H])C2([H])[H])C([H])([H])C1([H])[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
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[H]N(C(=O)N([H])[C@]1([H])C([H])([H])C([H])([H])N(C(=O)C2([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])[C@@]1([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])[C@@]([H])(C([H])([H])C2=C([H])C([H])=C(F)C([H])=C2[H])C1([H])[H])C1=NC(=C(S1)C(=O)C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)N([H])[C@]1([H])C([H])([H])N(C([H])([H])C#N)C([H])([H])C([H])([H])[C@@]1([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])[C@@]([H])(C([H])([H])C2=C([H])C([H])=C(F)C([H])=C2[H])C1([H])[H])C1=NC(=C(S1)C(=O)C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)N([H])[C@]1([H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])F)C([H])([H])[C@@]1([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])[C@@]([H])(C([H])([H])C2=C([H])C([H])=C(F)C([H])=C2[H])C1([H])[H])C1=NC(=C(S1)C(=O)C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)N([H])[C@]1([H])C([H])([H])C([H])([H])N(C([H])([H])C#N)C([H])([H])[C@@]1([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])[C@@]([H])(C([H])([H])C2=C([H])C([H])=C(F)C([H])=C2[H])C1([H])[H])C1=NC(=C(S1)C(=O)C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)N([H])[C@]1([H])C([H])([H])C([H])([H])N(C(=O)OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])[C@@]1([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])[C@@]([H])(C([H])([H])C2=C([H])C([H])=C(F)C([H])=C2[H])C1([H])[H])C1=NC(=C(S1)C(=O)C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)N([H])[C@]1([H])C([H])([H])C([H])([H])N(C(=O)N([H])C([H])([H])C([H])([H])[H])C([H])([H])[C@@]1([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])[C@@]([H])(C([H])([H])C2=C([H])C([H])=C(F)C([H])=C2[H])C1([H])[H])C1=NC(=C(S1)C(=O)C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)N([H])[C@]1([H])C([H])([H])C([H])([H])N(C(=O)C([H])([H])OC([H])([H])[H])C([H])([H])[C@@]1([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])[C@@]([H])(C([H])([H])C2=C([H])C([H])=C(F)C([H])=C2[H])C1([H])[H])C1=NC(=C(S1)C(=O)C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)N([H])[C@]1([H])C([H])([H])S(=O)(=O)C([H])([H])[C@@]1([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])[C@@]([H])(C([H])([H])C2=C([H])C([H])=C(F)C([H])=C2[H])C1([H])[H])C1=NC(=C(S1)C(=O)C([H])([H])[H])C([H])([H])[H]
[H]N1C([H])([H])C([H])([H])[C@]([H])(N(C([H])([H])C2=C(C(=C([H])C([H])=C2[H])C(F)(F)F)C([H])([H])[H])C2([H])C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])C1([H])[H]
[H]N1C([H])([H])C([H])([H])[C@]([H])(N(C([H])([H])C2=C(C(=C([H])C([H])=C2[H])C([H])([H])[H])C([H])([H])[H])C2([H])C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])C1([H])[H]
[H]C1=C(SC2=C1N=C([H])N(C2=O)[C@]1([H])C([H])([H])N(C(=O)N(C([H])([H])[H])[C@]2([H])C([H])([H])N(C([H])([H])C2([H])[H])C2([H])C([H])([H])C([H])([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]N1C([H])([H])C([H])([H])[C@]([H])(N(C([H])([H])C2=C(Cl)C(Cl)=C([H])C([H])=C2[H])C2([H])C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])C1([H])[H]
[H]N1C([H])([H])C([H])([H])[C@]([H])(N(C([H])([H])C2=C(Cl)C(Cl)=C([H])C([H])=C2[H])C([H])([H])C2([H])C([H])([H])C2([H])[H])C1([H])[H]
[H]N(C(=O)N([H])[C@]1([H])C([H])([H])N(C([H])([H])C([H])([H])F)C([H])([H])C([H])([H])[C@@]1([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])[C@@]([H])(C([H])([H])C2=C([H])C([H])=C(F)C([H])=C2[H])C1([H])[H])C1=NC(=C(S1)C(=O)C([H])([H])[H])C([H])([H])[H]
[H]C1=C(SC2=C1N=C([H])N(C2=O)[C@]1([H])C([H])([H])N(C(=O)N(C([H])([H])[H])[C@]2([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])C3=C([H])C([H])=C([H])C([H])=C3[H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]N1C(=O)N(C([H])([H])C1(C1=C([H])C([H])=C(F)C([H])=C1[H])C1=C([H])C([H])=C(F)C([H])=C1[H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C([H])C(Cl)=C2[H])C([H])([H])C1([H])[H]
[H]C1=C([H])C([H])=C(C(=C1[H])C1=NC2=C(C([H])=C(C([H])=C2[H])C2=C([H])C([H])=C(Cl)C([H])=C2[H])C(=O)N1C([H])([H])[C@]1([H])C([H])([H])N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])[H]
[H]N(C(=O)N([H])[C@]1([H])C([H])([H])N(C(=O)OC([H])([H])[H])C([H])([H])C([H])([H])[C@@]1([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])[C@@]([H])(C([H])([H])C2=C([H])C([H])=C(F)C([H])=C2[H])C1([H])[H])C1=NC(=C(S1)C(=O)C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)N([H])[C@]1([H])C([H])([H])N(C(=O)C([H])([H])N(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])[C@@]1([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])[C@@]([H])(C([H])([H])C2=C([H])C([H])=C(F)C([H])=C2[H])C1([H])[H])C1=NC(=C(S1)C(=O)C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])C(=C([H])C([H])=C1Cl)C1=C([H])C2=C(N=C(N(C2=O)C([H])([H])[C@]2([H])C([H])([H])N(C([H])([H])C([H])([H])C2([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])=C1[H]
[H]N1C([H])([H])C([H])([H])[C@]([H])(N(C([H])([H])C2=C(C(OC([H])([H])[H])=C([H])C([H])=C2[H])C([H])([H])[H])C2([H])C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])C1([H])[H]
[H]C1=C([H])C([H])=C(C(=C1[H])C1=NC2=C(C([H])=C(OC3=C([H])C([H])=C(F)C([H])=C3[H])C([H])=C2[H])C(=O)N1C([H])([H])[C@]1([H])C([H])([H])N(C([H])([H])C([H])([H])C1([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])C(=C([H])C([H])=C1F)C1=C([H])C2=C(N=C(N(C2=O)C([H])([H])[C@]2([H])C([H])([H])N(C([H])([H])C([H])([H])C2([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])=C1[H]
[H]C1=C([H])C(OC2=C([H])C3=C(N=C(N(C3=O)C([H])([H])[C@]3([H])C([H])([H])N(C([H])([H])C([H])([H])C3([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])=C2[H])=C([H])C([H])=C1F
[H]C1=C([H])C(=C([H])C([H])=C1Cl)C1=C([H])C2=C(N=C(N(C2=O)C([H])([H])[C@]2([H])C([H])([H])N(C([H])([H])C([H])([H])C2([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C([H])=C1[H]
[H]C1=NC2=C(C([H])=C(C([H])=C2[H])C2=C([H])C([H])=C(Cl)C([H])=C2[H])C(=O)N1C([H])([H])[C@]1([H])C([H])([H])N(C([H])([H])C([H])([H])C1([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]O[C@]1([H])C([H])([H])N(C([H])([H])[C@@]([H])(N(C(=O)C([H])([H])C([H])([H])C(=O)N([H])C2=NC([H])=C([H])S2)C([H])([H])[H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]O[C@]1([H])C([H])([H])N(C([H])([H])[C@@]([H])(N(C(=O)N([H])C([H])([H])C(=O)N([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])[H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]O[C@]1([H])C([H])([H])N(C([H])([H])[C@@]([H])(N(C(=O)C([H])([H])C([H])([H])C(=O)N([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])[H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]O[C@]1([H])C([H])([H])N(C([H])([H])[C@@]([H])(N(C(=O)C([H])([H])C(=O)N([H])C2=NC([H])=C([H])S2)C([H])([H])[H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]OC([H])([H])[C@@]([H])(N([H])C1=C(C2=NC3=C(C([H])=C(C([H])=C3N2[H])N2C([H])=NC([H])=C2[H])C([H])([H])[H])C(=O)N([H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C1=NC([H])=C(C(=O)N([H])C([H])([H])C2=C([H])C([H])=C(F)C([H])=C2[H])C(=N1)C(F)(F)F)C1=C([H])C(Cl)=C([H])C([H])=C1[H]
[H]O[C@]1([H])C([H])([H])N(C([H])([H])[C@@]([H])(N(C(=O)C([H])([H])C(=O)N([H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])[H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]C1=C([H])C(=NN2N=C(N=C12)C(F)(F)F)N1C([H])([H])C([H])([H])[C@]([H])(C2=C(F)C([H])=C(F)C(F)=C2[H])[C@@]([H])([N+]([H])([H])[H])C1([H])[H]
[H]N(C(=O)N([H])[C@]1([H])C([H])([H])C([H])([H])N(C(=O)C([H])([H])N(C([H])([H])[H])C([H])([H])[H])C([H])([H])[C@@]1([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])[C@@]([H])(C([H])([H])C2=C([H])C([H])=C(F)C([H])=C2[H])C1([H])[H])C1=NC(=C(S1)C(=O)C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)N([H])[C@]1([H])C([H])([H])C([H])([H])C([H])([H])O[C@@]1([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])[C@@]([H])(C([H])([H])C2=C([H])C([H])=C(F)C([H])=C2[H])C1([H])[H])C1=NC(=C(S1)C(=O)C([H])([H])[H])C([H])([H])[H]
[H]N(\C([H])=C(/[H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])[C@@]([H])(C([H])([H])C2=C([H])C([H])=C(F)C([H])=C2[H])C1([H])[H])C(=O)N([H])C1=C([H])C([H])=C([H])C(=C1[H])C(=O)C([H])([H])[H]
[H]N(C(=O)N([H])[C@]1([H])C([H])([H])N(C(=O)C2([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C([H])([H])[C@@]1([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])[C@@]([H])(C([H])([H])C2=C([H])C([H])=C(F)C([H])=C2[H])C1([H])[H])C1=NC(=C(S1)C(=O)C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)N([H])[C@]1([H])C([H])([H])N(C([H])([H])C(=O)C([H])([H])[H])C([H])([H])C([H])([H])[C@@]1([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])[C@@]([H])(C([H])([H])C2=C([H])C([H])=C(F)C([H])=C2[H])C1([H])[H])C1=NC(=C(S1)C(=O)C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)N([H])[C@]1([H])C([H])([H])OC([H])([H])C([H])([H])[C@@]1([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])[C@@]([H])(C([H])([H])C2=C([H])C([H])=C(F)C([H])=C2[H])C1([H])[H])C1=NC(=C(S1)C(=O)C([H])([H])[H])C([H])([H])[H]
[H]O[C@]1([H])C([H])([H])N(C([H])([H])[C@@]([H])(N(C(=O)C([H])([H])C(=O)N([H])C2=C([H])C([H])=C(C([H])=C2[H])C([H])([H])N([H])S(=O)(=O)C([H])([H])[H])C([H])([H])[H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]O[C@]1([H])C([H])([H])N(C([H])([H])[C@@]([H])(N(C(=O)C([H])([H])C(=O)N([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])[H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N(C([H])([H])[C@@]1([H])C([H])([H])N(C(=O)C2([H])C([H])([H])C([H])([H])N(C3=C([H])C([H])=NC([H])=C3[H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H])S(=O)(=O)C(\[H])=C(/[H])C1=C([H])C([H])=C(S1)C1=C([H])C([H])=C(Cl)S1
[H]C1=C([H])N(N=N1)C([H])([H])[C@]1([H])OC(=O)N(C2=C([H])C([H])=C(C(F)=C2[H])C2=C([H])N=C([H])C([H])=C2[H])C1([H])[H]
[H]N(C(=O)C1=C([H])C(Cl)=C(Cl)C([H])=C1[H])[C@]1([H])C([H])([H])N(C([H])([H])C2=C([H])C(Br)=C(OC3([H])C([H])([H])C([H])([H])N([H])C([H])([H])C3([H])[H])C([H])=C2[H])C([H])([H])C1([H])[H]
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[H]N(C1=C(C2=NC3=C(C([H])=C(C([H])=C3N2[H])N2C([H])=NC([H])=C2[H])C([H])([H])[H])C(=O)N([H])C([H])=C1[H])C([H])([H])C1=NC([H])=C([H])C([H])=C1[H]
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[H]OC1=C([H])C([H])=C(\C([H])=C(/[H])C(=O)C(\[H])=C(/[H])C2=C([H])C([H])=C(O[H])C([H])=C2[H])C([H])=C1[H]
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[H]N([H])C([H])([H])C1=NOC(=N1)C1=NN(C2=C([H])C([H])=C([H])C([H])=C12)C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N([H])C([H])([H])C1=NOC(=N1)C1=NN([H])C2=C([H])C([H])=C([H])C([H])=C12
[H]N([H])C(=O)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1N=C(C2=NC(=NO2)C([H])([H])N([H])[H])C2=C([H])C([H])=C([H])C([H])=C12
[H]N([H])C([H])([H])C1=NOC(=N1)C1=NN(C2=C([H])C([H])=C([H])C([H])=C12)C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N([H])C([H])([H])C1=NOC(=N1)C1=NN(C2=C([H])C([H])=C([H])C([H])=C12)S(=O)(=O)C1=C([H])C([H])=C(OC([H])([H])[H])C(OC([H])([H])[H])=C1[H]
[H]N(C(=O)OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=NOC(=N1)C1=NN(C2=C([H])C([H])=C([H])C([H])=C12)C([H])([H])C1=C([H])C([H])=C2OC([H])([H])OC2=C1[H]
[H]N([H])C([H])([H])C1=NOC(=N1)C1=NN(C2=C([H])C([H])=C([H])C([H])=C12)C([H])([H])C1=C([H])C(=C([H])C(=C1[H])C([H])([H])[H])C([H])([H])[H]
[H]N([H])C([H])([H])C1=NOC(=N1)C1=NN(C2=C([H])C([H])=C([H])C([H])=C12)C([H])([H])C1=C([H])C([H])=C([H])C(=C1[H])C([H])([H])[H]
[H]N([H])C([H])([H])C1=NOC(=N1)C1=C2C([H])=C([H])C([H])=C([H])C2=NN1C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]O[C@@]([H])(C([H])([H])OC1=C(C#N)C(Cl)=C([H])C([H])=C1[H])C([H])([H])N([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C2C([H])=C([H])C([H])=C([H])C2=C1[H]
[H]O[C@@]([H])(C([H])([H])[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)OC([H])([H])[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC([H])=C([H])C([H])=C1[H])[C@@]([H])(N([H])C(=O)[C@@]([H])(N1C(=O)N(C([H])([H])C2=NC(=C([H])C([H])=C2[H])C(O[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]O[C@@]([H])(C([H])([H])OC1=C(C#N)C([H])=C([H])C([H])=C1[H])C([H])([H])N([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]O[C@@]([H])(C([H])([H])OC1=C(C#N)C(Cl)=C([H])C([H])=C1[H])C([H])([H])N([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]O[C@]([H])(C([H])([H])OC1=C2N([H])C(=O)N([H])C2=C([H])C([H])=C1[H])C([H])([H])N([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]N(C([H])([H])[H])C([H])([H])C([H])([H])[C@@]([H])(OC1=C(C#N)C([H])=C([H])C(Cl)=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N([H])C([H])([H])C([H])([H])[C@@]([H])(OC1=C(C#N)C([H])=C([H])C(Cl)=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N([H])C([H])([H])C([H])([H])[C@@]([H])(SC1=C(C#N)C([H])=C([H])C(Cl)=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C([H])([H])[H])C([H])([H])C([H])([H])[C@@]([H])(OC1=C(C#N)C([H])=C([H])C(=C1[H])C(F)(F)F)C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C([H])([H])[H])C([H])([H])C([H])([H])[C@@]([H])(OC1=C(C#N)C([H])=C([H])C(OC([H])([H])[H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C([H])([H])[H])C([H])([H])C([H])([H])[C@]([H])(OC1=C(C#N)C([H])=C([H])C(Cl)=C1[H])C([H])([H])C([H])([H])[H]
[H]N([H])C([H])([H])C([H])([H])[C@@]([H])(OC1=C(C#N)C([H])=C(F)C(Cl)=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N([H])C([H])([H])C([H])([H])[C@@]([H])(SC1=C(C#N)C([H])=C([H])C(=N1)C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N1N=C(C([H])=C1C(=O)N1C([H])([H])C([H])([H])N(C2=C(OC([H])([H])[H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]OC1=C([H])C(N([H])C2=C([H])C([H])=NC3=C([H])C(Cl)=C([H])C([H])=C23)=C([H])C([H])=C1C([H])([H])N([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]OC1=C([H])C(N([H])C2=C([H])C([H])=NC3=C([H])C(Cl)=C([H])C([H])=C23)=C([H])C([H])=C1C([H])([H])N([H])C([H])([H])C([H])([H])[H]
[H]N([C@@]([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H])[C@@]1([H])C2=C(C3=C([H])C(Br)=C([H])C([H])=C3N2[H])C([H])([H])C([H])([H])C1([H])[H]
[H]OC(=O)[C@]([H])(OC1=C([H])C([H])=C([H])C(=C1[H])C([H])([H])N1C2=C([H])C(OC(F)(F)F)=C([H])C([H])=C2C(C(=O)C2=C([H])C([H])=C(Cl)C([H])=C2[H])=C1C([H])([H])[H])C([H])([H])C([H])([H])[H]
[H]OC1=C(C(=O)O[C@@](C([H])([H])C([H])([H])C2=C([H])C([H])=C(C(F)=C2[H])C(C#N)(C([H])([H])[H])C([H])([H])[H])(C1([H])[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C1=NN2C(=N1)N=C(C([H])=C2C([H])([H])[H])C([H])([H])[H]
[H]OC1=C(C(=O)O[C@@](C([H])([H])C([H])([H])C2=C([H])C([H])=C(C(F)=C2[H])C(C#N)(C([H])([H])[H])C([H])([H])[H])(C1([H])[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C1=C([H])N2C([H])=C([H])C([H])=C([H])C2=N1
[H]OC1=C(C(=O)O[C@@](C([H])([H])C([H])([H])C2=C([H])C([H])=C(C(F)=C2[H])C(C#N)(C([H])([H])[H])C([H])([H])[H])(C1([H])[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C(OC([H])([H])[H])=C1[H]
[H]OC1=C(C(=O)O[C@@](C([H])([H])C([H])([H])C2=C([H])C([H])=C(C(Cl)=C2[H])C(C#N)(C([H])([H])[H])C([H])([H])[H])(C1([H])[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C1=NN2C(=N1)N=C(C([H])=C2C([H])([H])[H])C([H])([H])[H]
[H]OC1=C(C(=O)O[C@@](C([H])([H])C([H])([H])C2=C([H])C([H])=C(C(F)=C2[H])C(C#N)(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H])(C1([H])[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C1=NN2C(=N1)N=C(C([H])=C2C([H])([H])[H])C([H])([H])[H]
[H]OC1=C(C(=O)O[C@@](C([H])([H])C([H])([H])C2=C([H])C([H])=C(C(F)=C2[H])C(O[H])(C([H])([H])[H])C([H])([H])[H])(C1([H])[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C1=NN2C(=N1)N=C(C([H])=C2C([H])([H])[H])C([H])([H])[H]
[H]N(C([H])([H])[H])C([H])([H])C([H])([H])[C@]([H])(OC1=C([H])C([H])=C([H])C2=C([H])C([H])=C([H])C([H])=C12)C1=C([H])C([H])=C([H])S1
[H]N1C([H])([H])C([H])([H])C([H])([H])[C@]([H])(C1([H])[H])[C@]([H])(OC1=C(Cl)C(Cl)=C([H])C([H])=C1[H])C1=C([H])N=C([H])C([H])=C1[H]
[H]N1C([H])([H])C([H])([H])[C@@]([H])(C1([H])[H])[C@]([H])(OC1=C(Cl)C(Cl)=C([H])C([H])=C1[H])C1=NC([H])=C([H])C([H])=C1[H]
[H]OC1=C([H])C2=C(N([H])C([H])=C2C([H])([H])[C@]([H])(N([H])C(=O)C2=C([H])C3=C(C([H])=C2[H])N(C(=N3)C2=C([H])OC([H])=C2[H])C2([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C2=C([H])SC([H])=N2)C([H])=C1[H]
[H]C1=C([H])N(C([H])=N1)C1=NN=C(C([H])=C1[H])N1C([H])([H])C([H])([H])C([H])(OC2=C([H])C([H])=C([H])C([H])=C2C(F)(F)F)C([H])([H])C1([H])[H]
[H]N(C(=O)C1=NN([H])C(=C1[H])C([H])([H])[H])[C@@]1([H])C2=C([H])C(=C(N=C2OC(C([H])([H])[H])(C([H])([H])[H])C1([H])[H])C1=C([H])C([H])=C(Cl)C([H])=C1Cl)C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]N([H])[C@]([H])(C([H])([H])OC1=C([H])C(=C(N=C1[H])C1=C([H])OC([H])=C1[H])C1=C([H])C2=C(N([H])N=C2C([H])([H])[H])C([H])=C1[H])C([H])([H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H]
[H]N(C([H])([H])[H])C([H])([H])C1=C([H])C(=O)OC2=C([H])C(OC([H])([H])C3=C([H])C(Cl)=C([H])C([H])=C3[H])=C([H])C([H])=C12
[H]OC(=O)C([H])([H])C([H])([H])C1=C([H])C(C#N)=C(OC([H])([H])[C@]([H])(O[H])C([H])([H])N([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C2=C([H])C([H])=C3C([H])=C([H])C([H])=C([H])C3=C2[H])C([H])=C1[H]
[H]O[C@@]([H])(C([H])([H])OC1=C(C#N)C([H])=C([H])C([H])=C1[H])C([H])([H])N([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C2C([H])=C([H])C([H])=C([H])C2=C1[H]
[H]O[C@@]([H])(C([H])([H])OC1=C([H])C([H])=C(C([H])=C1C#N)C([H])([H])C([H])([H])C(=O)OC([H])([H])C([H])([H])[H])C([H])([H])N([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C2C([H])=C([H])C([H])=C([H])C2=C1[H]
[H]OC(=O)C([H])([H])C([H])([H])C1=C([H])C([H])=C(OC([H])([H])[C@]([H])(O[H])C([H])([H])N([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C2=C([H])C([H])=C3C([H])=C([H])C([H])=C([H])C3=C2[H])C([H])=C1[H]
[H]N(C1=NC(N([H])C2([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])=C([H])C(=N1)C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OP(=O)(O[H])O[C@@]1([H])C([H])=C(N([H])C2=C([H])C3=C(OC([H])([H])O3)C([H])=C12)C1=C([H])C([H])=C([H])C([H])=C1F
[H]N1C([H])=C(C(=O)C(=O)N2C([H])([H])C([H])([H])N(C(=O)C3=C([H])C([H])=C([H])C([H])=C3[H])C([H])([H])[C@@]2([H])C([H])([H])[H])C2=C(OC([H])([H])[H])C([H])=C([H])N=C12
[H]N1C([H])=C(C(=O)C(=O)N2C([H])([H])C([H])([H])N(C(=O)C3=C([H])C([H])=C([H])C([H])=C3[H])C([H])([H])[C@@]2([H])C([H])([H])[H])C2=C([H])C([H])=C([H])C([H])=C12
[H]C1=C([H])C(F)=C(F)C(=C1[H])C([H])([H])N(C1=C([H])C([H])=C(C#N)C(Cl)=C1[H])[C@]1([H])C([H])([H])N(C(=O)OC([H])([H])[H])C([H])([H])C1([H])[H]
[H]C1=C([H])C([H])=C(C(Br)=C1[H])C([H])([H])N(C1=C([H])C([H])=C(C#N)C(Cl)=C1[H])[C@]1([H])C([H])([H])N(C(=O)C([H])([H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]C1=C([H])C([H])=C(C(=C1[H])C([H])([H])N(C1=C([H])C([H])=C(C#N)C(Cl)=C1[H])[C@]1([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H])C(F)(F)F
[H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N(C1=C([H])C([H])=C(C#N)C(Cl)=C1[H])[C@]1([H])C([H])([H])N(C(=O)OC([H])([H])[H])C([H])([H])C1([H])[H]
[H]C1=C([H])C([H])=C(C(=C1[H])C([H])([H])N(C1=C([H])C([H])=C(C#N)C(Cl)=C1[H])[C@]1([H])C([H])([H])N(C(=O)OC([H])([H])[H])C([H])([H])C1([H])[H])C(F)(F)F
[H]C1=C([H])C([H])=C(C(F)=C1[H])C([H])([H])N(C1=C([H])C([H])=C(C#N)C(Cl)=C1[H])[C@]1([H])C([H])([H])N(C(=O)OC([H])([H])[H])C([H])([H])C1([H])[H]
[H]C1=NC(=C(C([H])=C1[H])C([H])([H])[H])[C@@]([H])(C1=C(SC2=C([H])C([H])=C([H])C([H])=C12)C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H]
[H]C1=NC(=C(OC([H])([H])[H])C([H])=C1[H])[C@@]([H])(C1=C(SC2=C([H])C([H])=C([H])C([H])=C12)C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H]
[H]C1=NC(=C(F)C([H])=C1[H])[C@@]([H])(C1=C(SC2=C([H])C([H])=C([H])C([H])=C12)C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H]
[H]C1=NC(=C(Cl)C([H])=C1[H])[C@@]([H])(C1=C(SC2=C([H])C([H])=C([H])C([H])=C12)C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])C([H])=C(C(OC([H])([H])[H])=N1)[C@]([H])(C1=C(SC2=C([H])C([H])=C([H])C([H])=C12)C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])C([H])=C(C(F)=N1)[C@]([H])(C1=C(SC2=C([H])C([H])=C([H])C([H])=C12)C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])C([H])=C(C(Cl)=N1)[C@]([H])(C1=C(SC2=C([H])C([H])=C([H])C([H])=C12)C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H]
[H]N(C([H])([H])[H])C([H])([H])C([H])([H])C1=C(C2=C([H])C([H])=C([H])C([H])=C2S1)[C@]([H])(C1=C([H])C([H])=C([H])C([H])=N1)C([H])([H])[H]
[H]C1=NC(=C([H])C([H])=C1[H])[C@@]([H])(C1=C(SC2=C([H])C([H])=C([H])C([H])=C12)C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])[H]
[H]C1=C([H])C([H])=C(C([H])=N1)[C@]([H])(C1=C(SC2=C([H])C([H])=C([H])C([H])=C12)C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H]
[H]C1=NC([H])=C([H])C(=C1[H])[C@]([H])(C1=C(SC2=C([H])C([H])=C([H])C([H])=C12)C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H]
[H]N1C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])[C@@]([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C(OC([H])(F)F)C([H])=C([H])C([H])=C1[H]
[H]N1C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])[C@@]([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C(OC(F)(F)F)C([H])=C([H])C([H])=C1[H]
[H]N1C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])[C@@]([H])(C1=C(F)C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C(OC(F)(F)F)C([H])=C([H])C([H])=C1[H]
[H]N([H])C1=C(N([H])C(=O)C(\[H])=C(/[H])C2=C([H])C(F)=C(C([H])=C2[H])[C@@]2([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[C@]2([H])C(=O)N([H])C2=C([H])C([H])=C(Cl)C([H])=C2[H])C([H])=C([H])C([H])=C1[H]
[H]OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])N1C([H])([H])[C@]([H])(C(=O)N([H])C2=C([H])C([H])=C(Cl)C([H])=C2[H])[C@@]([H])(C2=C([H])C([H])=C(\C([H])=C(/[H])C(=O)N([H])C3=C(N([H])[H])C([H])=C([H])C([H])=C3[H])C([H])=C2[H])C1([H])[H]
[H]C1=C([H])C2=C(C([H])=C1[H])N(C(=N2)N1C([H])([H])C([H])([H])C([H])(N(C([H])([H])[H])C2([H])C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])C([H])([H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]N(C([H])([H])[H])C1([H])C([H])([H])C([H])([H])N(C2=NC3=C(C([H])=C([H])C([H])=C3[H])N2C([H])([H])C2=C([H])C([H])=C(F)C([H])=C2[H])C([H])([H])C1([H])[H]
[H]C1=C([H])C2=C(C([H])=C1[H])N(C(=N2)N1C([H])([H])C([H])([H])C([H])(N(C([H])([H])[H])C2([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]C1=NN(C([H])=C1C([H])([H])[H])C1([H])C([H])([H])C([H])([H])N(C2=NC3=C([H])C([H])=C([H])C([H])=C3N2C([H])([H])C2=C([H])C([H])=C(OC([H])([H])[H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]C1=C([H])N(C([H])=C1[H])C1([H])C([H])([H])C([H])([H])N(C2=NC3=C([H])C([H])=C([H])C([H])=C3N2C([H])([H])C2=C([H])C([H])=C(F)C([H])=C2[H])C([H])([H])C1([H])[H]
[H]C1=C([H])C2=C(C([H])=C1[H])N(C(=N2)N1C([H])([H])C([H])([H])C([H])(N(C([H])([H])[H])C([H])([H])C2([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])N(C([H])([H])[H])C1([H])C([H])([H])C([H])([H])N(C2=NC3=C(C([H])=C([H])C([H])=C3[H])N2C([H])([H])C2=C([H])C([H])=C(F)C([H])=C2[H])C([H])([H])C1([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N(C([H])([H])[H])C1([H])C([H])([H])C([H])([H])N(C2=NC3=C(C([H])=C([H])C([H])=C3[H])N2C([H])([H])C2=C([H])C([H])=C(F)C([H])=C2[H])C([H])([H])C1([H])[H]
[H]C1=NC(=NC([H])=C1[H])N(C([H])([H])[H])C1([H])C([H])([H])C([H])([H])N(C2=NC3=C(C([H])=C([H])C([H])=C3[H])N2C([H])([H])C2=C([H])C([H])=C(F)C([H])=C2[H])C([H])([H])C1([H])[H]
[H]C1=NN(C([H])=C1C([H])([H])[H])C1([H])C([H])([H])C([H])([H])N(C2=NC3=C([H])C([H])=C([H])C([H])=C3N2C([H])([H])C2=C([H])C([H])=C(F)C([H])=C2[H])C([H])([H])C1([H])[H]
[H]C1=NN(C([H])=C1[H])C1([H])C([H])([H])C([H])([H])N(C2=NC3=C([H])C([H])=C([H])C([H])=C3N2C([H])([H])C2=C([H])C([H])=C(F)C([H])=C2[H])C([H])([H])C1([H])[H]
[H]C1=C([H])N(C([H])=N1)C1([H])C([H])([H])C([H])([H])N(C2=NC3=C([H])C([H])=C([H])C([H])=C3N2C([H])([H])C2=C([H])C([H])=C(F)C([H])=C2[H])C([H])([H])C1([H])[H]
[H]C1=C([H])C([H])=C2N(C(=NC2=C1[H])N1C([H])([H])C([H])([H])C([H])(N2C(=O)C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]C1=C([H])C([H])=C2N(C(=NC2=C1[H])N1C([H])([H])C([H])([H])C([H])(N(C([H])([H])[H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]C1=C([H])C([H])=C2N(C(=NC2=C1[H])N1C([H])([H])C([H])([H])C([H])(N(C([H])([H])[H])C([H])([H])C([H])([H])OC([H])([H])[H])C([H])([H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]C1=C([H])C([H])=C2N(C(=NC2=C1[H])N1C([H])([H])C([H])([H])C([H])(N(C([H])([H])[H])C([H])([H])C2([H])C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])C([H])([H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]C1=C([H])C([H])=C2N(C(=NC2=C1[H])N1C([H])([H])C([H])([H])C([H])(N(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]C1=C([H])C([H])=C2N(C(=NC2=C1[H])N1C([H])([H])C([H])([H])C([H])(N(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H]
[H]OC([H])([H])C1=C(C([H])=C([H])C([H])=C1[H])S(=O)(=O)C1=C([H])C([H])=C(\C([H])=C(/[H])C2=C([H])C([H])=C(F)C([H])=C2[H])C([H])=C1[H]
[H]OC(=O)C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C1=C(SC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C2=C([H])C(OC([H])([H])C3=NC([H])=C([H])C([H])=C3[H])=C([H])C([H])=C2N1C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C([H])N=C1[H]
[H]OC(=O)C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C1=C(SC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C2=C([H])C(OC([H])([H])C3=NC([H])=C([H])C([H])=C3[H])=C([H])C([H])=C2N1C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC([H])=C([H])S1
[H]OC(=O)C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C1=C(SC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C2=C([H])C(OC([H])([H])C3=C([H])C([H])=C4C([H])=C([H])C([H])=C([H])C4=N3)=C([H])C([H])=C2N1C([H])([H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]OC(=O)C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C1=C(SC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C2=C([H])C(OC([H])([H])C3=NC([H])=C([H])C([H])=C3[H])=C([H])C([H])=C2N1C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC([H])=C([H])C([H])=N1
[H]OC(=O)C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C1=C(SC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C2=C([H])C(OC([H])([H])C3=NC([H])=C([H])C([H])=C3[H])=C([H])C([H])=C2N1C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C(N=C1[H])C([H])([H])[H]
[H]OC(=O)C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C1=C(SC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C2=C([H])C(OC([H])([H])C3=NC([H])=C([H])C([H])=C3[H])=C([H])C([H])=C2N1C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC([H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]OC(=O)C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C1=C(SC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C2=C([H])C(OC([H])([H])C3=NC([H])=C([H])C([H])=C3[H])=C([H])C([H])=C2N1C([H])([H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]OC(=O)C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C1=C(SC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C2=C([H])C(OC([H])([H])C3=NC([H])=C([H])C([H])=C3[H])=C([H])C([H])=C2N1C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NN=C(OC([H])([H])[H])C([H])=C1[H]
[H]OC(=O)C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C1=C(SC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C2=C([H])C(OC([H])([H])C3=NC([H])=C([H])C([H])=C3[H])=C([H])C([H])=C2N1C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C(OC([H])([H])[H])N=C1[H]
[H]C1=C([H])C(=C([H])C2=C1N1C(=N2)C([H])([H])[C@]([H])(C2=C(F)C([H])=C(F)C(F)=C2[H])[C@@]([H])([N+]([H])([H])[H])C1([H])[H])S(=O)(=O)C([H])([H])[H]
[H]C([H])=C([H])C([H])([H])[C@]([H])(OC([H])([H])[H])[C@@]12C([H])([H])[C@@]1(C1=C([H])C(Cl)=C(Cl)C([H])=C1[H])C([H])([H])C([H])([H])N([H])C2([H])[H]
[H]N1C([H])([H])C([H])([H])[C@]2(C3=C([H])C([H])=C4C([H])=C([H])C([H])=C([H])C4=C3[H])C([H])([H])[C@]2(C([H])([H])OC([H])([H])[H])C1([H])[H]
[H]N1C([H])([H])C([H])([H])[C@]2(C3=C([H])C([H])=C(Cl)C(Cl)=C3[H])C([H])([H])[C@]2(C([H])([H])OC([H])([H])[H])C1([H])[H]
[H]C1=C([H])C2=C(N=C3N2C([H])([H])[C@]([H])([N+]([H])([H])[H])[C@@]([H])(C2=C(F)C([H])=C(F)C(F)=C2[H])C3([H])[H])[N+]([H])=C1[H]
[H]N(C([H])([H])[H])C([H])([H])C1=C(OC2=C(OC3=C([H])C([H])=C([H])C([H])=C3[H])C([H])=C([H])C([H])=C2[H])C([H])=C(N=C1[H])C([H])([H])[H]
[H]N1C([H])([H])C([H])([H])[C@]([H])(N(C(=O)C2=C(SC([H])([H])C([H])([H])[H])C([H])=C([H])C([H])=C2[H])C([H])([H])C2([H])C([H])([H])C([H])([H])C2([H])[H])C1([H])[H]
[H]N1C([H])([H])C([H])([H])[C@]([H])(N(C(=O)C2=C(C([H])=C([H])C([H])=C2[H])C2([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C2([H])C([H])([H])C([H])([H])C2([H])[H])C1([H])[H]
[H]N1C([H])([H])C([H])([H])[C@]([H])(N(C(=O)C2=C(OC3=C([H])C([H])=C([H])C([H])=C3[H])C([H])=C([H])C([H])=C2[H])C([H])([H])C2([H])C([H])([H])C([H])([H])C2([H])[H])C1([H])[H]
[H]N1C([H])([H])C([H])([H])[C@]([H])(N(C(=O)C2=C(C([H])=C([H])C([H])=C2[H])C(F)(F)F)C2=C([H])C([H])=C([H])C([H])=C2[H])C1([H])[H]
[H]N1C([H])([H])C([H])([H])[C@]([H])(N(C(=O)C2=C(OC3=C([H])C([H])=C([H])C([H])=C3[H])C([H])=C([H])C([H])=C2[H])C2([H])C([H])([H])C([H])([H])C2([H])[H])C1([H])[H]
[H]N1C([H])([H])C([H])([H])[C@]([H])(N(C(=O)C2=C(OC3=C([H])C([H])=C([H])C([H])=C3[H])C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C1([H])[H]
[H]N1C([H])([H])C([H])([H])[C@]([H])(N(C(=O)C2=C(OC3=C([H])C([H])=C([H])C([H])=C3[H])C([H])=C([H])C([H])=C2[H])C2=C([H])C([H])=C([H])C([H])=C2[H])C1([H])[H]
[H]N1N=C([H])C2=C([H])C(=C([H])C([H])=C12)N1C([H])([H])C([H])([H])N([H])C([H])([H])[C@]1([H])C([H])([H])C1([H])C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]N1N=C([H])C2=C([H])C(=C([H])C([H])=C12)N1C([H])([H])C([H])([H])N([H])C([H])([H])[C@]1([H])C([H])([H])C([H])([H])OC([H])([H])[H]
[H]N1N=C([H])C2=C([H])C(=C([H])C([H])=C12)N1C([H])([H])C([H])([H])N([H])C([H])([H])[C@@]1([H])C([H])([H])OC([H])([H])C([H])([H])[H]
[H]N1N=C([H])C2=C([H])C(=C([H])C([H])=C12)N1C([H])([H])C([H])([H])N([H])C([H])([H])[C@@]1([H])C([H])([H])OC([H])([H])[H]
[H]N1N=C([H])C2=C([H])C(=C([H])C([H])=C12)N1C([H])([H])C([H])([H])N([H])C([H])([H])[C@]1([H])C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N1N=C([H])C2=C([H])C(=C([H])C([H])=C12)N1C([H])([H])C([H])([H])N([H])C([H])([H])[C@@]1([H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N1N=C([H])C2=C([H])C(=C([H])C([H])=C12)N1C([H])([H])C([H])([H])N([H])C([H])([H])[C@]1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]N1N=C([H])C2=C([H])C(=C([H])C([H])=C12)N1C([H])([H])C([H])([H])N([H])C([H])([H])[C@]1([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N1N=C([H])C2=C([H])C(=C([H])C([H])=C12)N1C([H])([H])C([H])([H])N([H])C([H])([H])[C@@]1([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N1N=C([H])C2=C([H])C(=C([H])C([H])=C12)N1C([H])([H])C([H])([H])N([H])C([H])([H])[C@@]1([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC1=C([H])C(=C([H])C([H])=C1[H])C1=C([H])C(=C([H])S1)C1=C([H])C([H])=C(O[H])C(=C1[H])C([H])([H])[H]
[H]OC1=C([H])C(=C([H])C([H])=C1[H])C1=C([H])C([H])=C(S1)C1=C([H])C([H])=C(O[H])C(F)=C1[H]
[H]OC1=C([H])C(=C([H])C([H])=C1[H])C1=C([H])C([H])=C(S1)C1=C([H])C([H])=C(O[H])C(=C1[H])C([H])([H])[H]
[H]C1=NC(OC([H])([H])[H])=C(N=C1[H])[C@@]([H])(C1=C(C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H])C([H])([H])C2=C([H])C(OC([H])([H])[H])=C([H])C([H])=C12)C([H])([H])[H]
[H]C1=NC(OC([H])([H])[H])=C(N=C1[H])[C@@]([H])(C1=C(C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H])C([H])([H])C2=C([H])C(F)=C([H])C([H])=C12)C([H])([H])[H]
[H]C1=C([H])N=C(S1)[C@@]([H])(C1=C(C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H])C([H])([H])C2=C([H])C(F)=C([H])C([H])=C12)C([H])([H])[H]
[H]C1=C([H])N=C(S1)[C@@]([H])(C1=C(C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H])C([H])([H])C2=C([H])C(=C([H])C([H])=C12)C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])N=C(S1)[C@@]([H])(C1=C(C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H])C([H])([H])C2=C([H])C(OC([H])([H])[H])=C([H])C([H])=C12)C([H])([H])[H]
[H]C1=NC([H])=C(N=C1[H])C([H])([H])C1=C(C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C12
[H]C1=C([H])C([H])=C2C(=C1[H])C(=C(C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H])C2([H])[H])C([H])([H])C1=C([H])N=C([H])C(=N1)C([H])([H])[H]
[H]C1=NC([H])=C(N=C1[H])C([H])([H])C1=C(C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H])C([H])([H])C2=C([H])C(=C([H])C([H])=C12)C([H])([H])[H]
[H]C1=NC([H])=C(N=C1[H])C([H])([H])C1=C(C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H])C([H])([H])C2=C([H])C(OC([H])([H])[H])=C([H])C([H])=C12
[H]C1=NC(OC([H])([H])[H])=C(N=C1[H])C([H])([H])C1=C(C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H])C([H])([H])C2=C([H])C(Cl)=C([H])C([H])=C12
[H]C1=C([H])C([H])=C2C(=C1[H])C(=C(C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H])C2([H])[H])C([H])([H])C1=C([H])N=C(C([H])=N1)C([H])([H])[H]
[H]C1=NC(OC([H])([H])[H])=C(N=C1[H])C([H])([H])C1=C(C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C12
[H]C1=NC(OC([H])([H])[H])=C(N=C1[H])C([H])([H])C1=C(C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H])C([H])([H])C2=C([H])C(F)=C([H])C([H])=C12
[H]C1=C([H])N=C(S1)[C@@]([H])(C1=C(C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C12)C([H])([H])[H]
[H]OC(=O)C([H])([H])C([H])([H])C1=C(OC([H])([H])C([H])([H])C([H])([H])C(=O)O[H])C([H])=C([H])C([H])=C1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])OC1=C([H])C(=C([H])C(=C1[H])C1=C([H])C2=C(OC([H])([H])O2)C([H])=C1[H])C1=C(F)C([H])=C([H])C([H])=C1[H]
[H]OC(=O)C([H])([H])C([H])([H])C1=C(OC([H])([H])C([H])([H])C([H])([H])C(=O)O[H])C([H])=C([H])C([H])=C1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])OC1=C([H])C(=C([H])C(=C1[H])C1=C([H])C2=C(OC([H])([H])O2)C([H])=C1[H])C1=C([H])C(F)=C([H])C([H])=C1[H]
[H]OC(=O)C([H])([H])C([H])([H])C1=C(OC([H])([H])C([H])([H])C([H])([H])C(=O)O[H])C([H])=C([H])C([H])=C1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])OC1=C([H])C(=C([H])C(=C1[H])C1=C([H])C2=C(OC([H])([H])O2)C([H])=C1[H])C1=C([H])SC([H])=C1[H]
[H]OC(=O)C([H])([H])C([H])([H])C1=C(OC([H])([H])C([H])([H])C([H])([H])C(=O)O[H])C([H])=C([H])C([H])=C1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])OC1=C([H])C(=C([H])C(=C1[H])C1=C([H])C([H])=NC([H])=C1[H])C1=C([H])C([H])=NC([H])=C1[H]
[H]OC(=O)C([H])([H])C([H])([H])C1=C(OC([H])([H])C([H])([H])C([H])([H])C(=O)O[H])C([H])=C([H])C([H])=C1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])OC1=C([H])C(=C([H])C(=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N1C([H])=NC(=C1[H])C([H])([H])C([H])([H])SC1=C([H])C([H])=C(C([H])=C1[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]OC(=O)C([H])([H])C([H])([H])C1=C(OC([H])([H])C([H])([H])C([H])([H])C(=O)O[H])C([H])=C([H])C([H])=C1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])OC1=C([H])C(=C([H])C(=N1)C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C1=C2C(N(C(=C2C([H])([H])[H])C([H])([H])[H])C([H])([H])[C@@]2([H])C([H])([H])[C@]2([H])C([H])([H])[H])=C(OC([H])([H])C2=C([H])C([H])=C(F)C([H])=C2[H])N=N1
[H]N(C1=NC(=C([H])C2=C1N([H])C(=C2C([H])([H])[H])C([H])([H])[H])N1C(=O)N([H])C([H])([H])C1([H])[H])C([H])([H])C1=C(C([H])=C([H])C([H])=C1C([H])([H])[H])C([H])([H])[H]
[H]N(C1=NC(=C([H])C2=C1N([H])C(=C2C([H])([H])[H])C([H])([H])[H])N1C(=O)C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C1=C(C([H])=C([H])C([H])=C1C([H])([H])[H])C([H])([H])[H]
[H]N(C1=NC(=C([H])C2=C1N([H])C(=C2C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C(C([H])=C([H])C([H])=C1C([H])([H])[H])C([H])([H])[H]
[H]N(C1=NC([H])=NC2=C1N([H])C(=C2C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C(C([H])=C([H])C([H])=C1C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])N2C(=NC(=C2C([H])([H])[H])C([H])([H])[H])C(OC([H])([H])C2=C(C([H])=C([H])C([H])=C2C([H])([H])[H])C([H])([H])[H])=C1[H]
[H]C1=C(C([H])=C([H])C(OC([H])([H])[H])=N1)C([H])([H])[C@]([H])(C([H])([H])[H])C([H])([H])N1C([H])([H])[C@@]([H])(C(=O)N2C([H])([H])C([H])([H])N(C3=C([H])C([H])=C(F)C(F)=C3[H])C([H])([H])C2([H])[H])[C@@]2([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@@]2([H])C1([H])[H]
[H]OC1=C([H])C2=C(O[C@](C([H])([H])[H])(C([H])([H])C([H])([H])C([H])([H])C(O[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C2=O)C([H])=C1Br
[H]OC1=C([H])C(C(=O)C(\[H])=C(/C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C(O[H])(C([H])([H])[H])C([H])([H])[H])=C(O[H])C([H])=C1Br
[H]N(C1=C([H])C([H])=C2C(=C1[H])C([H])([H])C([H])([H])N(C([H])([H])C1=NN([H])C([H])=C1[H])C([H])([H])C2([H])[H])S(=O)(=O)C1=C([H])C([H])=C(S1)C1=C([H])C([H])=C([H])C([H])=N1
[H]N(C1=C([H])C([H])=C2C(=C1[H])C([H])([H])C([H])([H])N(C([H])([H])C1=NN([H])C([H])=C1[H])C([H])([H])C2([H])[H])S(=O)(=O)C1=C([H])C2=C(OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C2([H])[H])C([H])=C1[H]
[H]N(C1=C([H])C([H])=C2C(=C1[H])C([H])([H])C([H])([H])N(C([H])([H])C1=NN([H])C([H])=C1[H])C([H])([H])C2([H])[H])S(=O)(=O)C1=C([H])C([H])=C(OC([H])(C([H])([H])[H])C([H])([H])[H])C([H])=C1[H]
[H]N(C1=C([H])C([H])=C2C(=C1[H])C([H])([H])C([H])([H])N(C([H])([H])C1=NN([H])C([H])=C1[H])C([H])([H])C2([H])[H])S(=O)(=O)C1=C([H])C([H])=C(C#N)C([H])=C1[H]
[H]N(C1=C([H])C([H])=C(C([H])=N1)S(=O)(=O)C([H])([H])C1=C([H])C([H])=C2C(=C1[H])C([H])([H])C([H])([H])N([H])C([H])([H])C2([H])[H])C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]N1C([H])([H])C([H])([H])C2=C([H])C([H])=C(C([H])=C2C([H])([H])C1([H])[H])C([H])([H])S(=O)(=O)C1=C([H])C([H])=C(N=C1[H])N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N1C([H])([H])C([H])([H])C2=C([H])C([H])=C(C([H])=C2C([H])([H])C1([H])[H])C([H])([H])S(=O)(=O)C1=C([H])C([H])=C(OC([H])(C([H])([H])[H])C([H])([H])[H])N=C1[H]
[H]N1C([H])([H])C([H])([H])C2=C([H])C([H])=C(C([H])=C2C([H])([H])C1([H])[H])C([H])([H])S(=O)(=O)C1=C([H])C([H])=C(OC2=C([H])C([H])=C(F)C([H])=C2[H])N=C1[H]
[H]N1C([H])([H])C([H])([H])C2=C([H])C([H])=C(C([H])=C2C([H])([H])C1([H])[H])C([H])([H])S(=O)(=O)C1=C([H])C([H])=C(N=C1[H])C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]N1C([H])([H])C([H])([H])C2=C([H])C([H])=C(C([H])=C2C([H])([H])C1([H])[H])C([H])([H])S(=O)(=O)C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C(F)=C(F)C([H])=C1[H]
[H]N1C([H])([H])C([H])([H])C2=C([H])C([H])=C(C([H])=C2C([H])([H])C1([H])[H])C([H])([H])S(=O)(=O)C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]O[C@@]([H])(C([H])([H])O[C@@]([H])(C1=C(C([H])=C([H])C([H])=C1[H])C([H])([H])[H])C1([H])C([H])([H])C1([H])[H])C([H])([H])N([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C2C([H])=C([H])C([H])=C([H])C2=C1[H]
[H]N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@]1([H])C([H])([H])N1C(=O)N(C2=C([H])C(Cl)=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]C1=NC(=C([H])N1C([H])([H])[H])C(=O)N(C([H])([H])C1=C([H])C([H])=C([H])C(OC(F)(F)F)=C1[H])[C@]1([H])C([H])([H])[C@]2([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[C@]2([H])C1([H])[H]
[H]N([H])[C@@]([H])(C([H])([H])C(=O)N1C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C([H])([H])N(C(=O)C1([H])C([H])([H])C1([H])[H])C([H])([H])[H])C([H])([H])C1=C(F)C([H])=C(F)C(F)=C1[H]
[H]N([H])[C@@]([H])(C([H])([H])C(=O)N1C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C([H])([H])N([H])C(=O)C(F)(F)C([H])([H])[H])C([H])([H])C1=C(F)C([H])=C(F)C(F)=C1[H]
[H]N([H])[C@@]([H])(C([H])([H])C(=O)N1C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C([H])([H])N([H])C(=O)C1(C([H])([H])C1([H])[H])C(F)(F)F)C([H])([H])C1=C(F)C([H])=C(F)C(F)=C1[H]
[H]N([H])[C@@]([H])(C([H])([H])C(=O)N1C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C([H])([H])OC([H])([H])C1([H])C([H])([H])C1([H])[H])C([H])([H])C1=C(F)C([H])=C(F)C(F)=C1[H]
[H]N([H])[C@@]([H])(C([H])([H])C(=O)N1C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C([H])([H])OC1=C([H])C([H])=NC(=N1)C(F)(F)F)C([H])([H])C1=C(F)C([H])=C(F)C(F)=C1[H]
[H]N([H])[C@@]([H])(C([H])([H])C(=O)N1C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C([H])([H])OC1=C([H])C(C#N)=C([H])C([H])=N1)C([H])([H])C1=C(F)C([H])=C(F)C(F)=C1[H]
[H]N([H])[C@@]([H])(C([H])([H])C(=O)N1C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C([H])([H])OC1=C([H])C([H])=C(C#N)C([H])=N1)C([H])([H])C1=C(F)C([H])=C(F)C(F)=C1[H]
[H]N([H])[C@@]([H])(C([H])([H])C(=O)N1C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C([H])([H])N([H])C1=NC([H])=C([H])C(=N1)C(F)(F)F)C([H])([H])C1=C(F)C([H])=C(F)C(F)=C1[H]
[H]N([H])[C@@]([H])(C([H])([H])C(=O)N1C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C([H])([H])N([H])C1=NC([H])=C(F)C([H])=N1)C([H])([H])C1=C(F)C([H])=C(F)C(F)=C1[H]
[H]N([H])[C@@]([H])(C([H])([H])C(=O)N1C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C([H])([H])N([H])C1=NC([H])=C([H])C([H])=N1)C([H])([H])C1=C(F)C([H])=C(F)C(F)=C1[H]
[H]N([H])[C@@]([H])(C([H])([H])C(=O)N1C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C([H])([H])N([H])C1=C([H])C([H])=C(N=C1[H])C(F)(F)F)C([H])([H])C1=C(F)C([H])=C(F)C(F)=C1[H]
[H]N([H])[C@@]([H])(C([H])([H])C(=O)N1C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C([H])([H])N([H])C1=C([H])C([H])=C(F)C([H])=N1)C([H])([H])C1=C(F)C([H])=C(F)C(F)=C1[H]
[H]N([H])[C@@]([H])(C([H])([H])C(=O)N1C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C([H])([H])N([H])C1=C(C#N)C([H])=C([H])C([H])=N1)C([H])([H])C1=C(F)C([H])=C(F)C(F)=C1[H]
[H]N1C([H])([H])[C@@]2([H])[C@@]([H])(C1([H])[H])[C@@]2(C1=C([H])C(Cl)=C(Cl)C([H])=C1[H])C([H])([H])OC([H])([H])C(F)(F)F
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[H]O[C@@]([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])N1C([H])([H])[C@@]2([H])C([H])([H])[C@@]([H])(N(C(=O)C3=C([H])N(C([H])=N3)C([H])([H])[H])C([H])([H])C3=C([H])C([H])=C([H])C(OC(F)(F)F)=C3[H])C([H])([H])[C@@]2([H])C1([H])[H]
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[H]N([H])[C@@]([H])(C([H])([H])C(=O)N1C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C([H])([H])N(C(=O)C(F)(F)C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C(F)C([H])=C(F)C(F)=C1[H]
[H]N([H])[C@@]([H])(C([H])([H])C(=O)N1C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C([H])([H])N([H])C1=C([H])C([H])=C(C#N)C([H])=N1)C([H])([H])C1=C(F)C([H])=C(F)C(F)=C1[H]
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[H]C1=NC(=C([H])N1C([H])([H])[H])C(=O)N(C([H])([H])C1=C([H])C([H])=C([H])C(OC(F)(F)F)=C1[H])[C@]1([H])C([H])([H])[C@]2([H])C([H])([H])N(C([H])([H])[C@]([H])(F)C([H])([H])[H])C([H])([H])[C@]2([H])C1([H])[H]
[H]OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])N1C([H])([H])[C@@]2([H])C([H])([H])[C@@]([H])(N(C(=O)C3=C([H])N(C([H])=N3)C([H])([H])[H])C([H])([H])C3=C([H])C([H])=C([H])C(OC(F)(F)F)=C3[H])C([H])([H])[C@@]2([H])C1([H])[H]
[H]N([H])[C@@]([H])(C([H])([H])C(=O)N1C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C([H])([H])N(C1=C([H])C([H])=C(C#N)C([H])=N1)C([H])([H])[H])C([H])([H])C1=C(F)C([H])=C(F)C(F)=C1[H]
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[H]C1=C([H])C([H])=C2C(=C1[H])C(=C(C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H])C2([H])[H])C([H])([H])C1=C([H])C([H])=C(F)C([H])=C1[H]
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[H]C1=NC(=C([H])C([H])=C1[H])[C@@]([H])(C1=C(OC2=C([H])C([H])=C([H])C([H])=C12)C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H]
[H]N1C([H])([H])C([H])([H])C2(OC3=C(C([H])=C([H])C([H])=C3[H])C(=C2[H])C2=C([H])C([H])=C(C([H])=C2[H])C(=O)N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C2(OC3=C1C([H])=C([H])C([H])=C3[H])C([H])([H])C([H])([H])N([H])C([H])([H])C2([H])[H])C([H])([H])C([H])([H])[H]
[H]N([H])C(=O)C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C2(OC3=C1C([H])=C([H])C([H])=C3[H])C([H])([H])C([H])([H])N([H])C([H])([H])C2([H])[H]
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[H]N1C([H])([H])C([H])([H])C2(OC3=C(C([H])=C([H])C([H])=C3[H])C(=C2[H])C2=C([H])C([H])=C(C([H])=C2[H])C(=O)N2C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]N1C([H])([H])C([H])([H])C2(OC3=C(C([H])=C([H])C([H])=C3[H])C(=C2[H])C2=C([H])C([H])=C(C([H])=C2[H])C(=O)N2C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]N1C([H])([H])C([H])([H])C2(OC3=C(C([H])=C([H])C([H])=C3[H])C(=C2[H])C2=C([H])C([H])=C(C([H])=C2[H])C(=O)N2C([H])([H])C3=C(C([H])=C([H])C([H])=C3[H])C2([H])[H])C([H])([H])C1([H])[H]
[H]N1C([H])([H])C([H])([H])C2(OC3=C(C([H])=C([H])C([H])=C3[H])C(=C2[H])C2=C([H])C([H])=C(C([H])=C2[H])C(=O)N(C([H])([H])[H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
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[H]N1C([H])([H])C([H])([H])C2(OC3=C(C([H])=C([H])C([H])=C3[H])C(=C2[H])C2=C([H])C([H])=C(O2)C(=O)N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N1C([H])([H])C([H])([H])C2(OC3=C(C([H])=C([H])C([H])=C3[H])C(=C2[H])C2=C([H])SC(=C2[H])C(=O)N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N1C([H])([H])C([H])([H])C2(OC3=C(C([H])=C([H])C([H])=C3[H])C(=C2[H])C2=C([H])C(=C(C([H])=C2[H])C(=O)N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H]
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[H]N([H])C1=C(C([H])=C([H])C([H])=C1[H])C([H])([H])N([H])C(=O)C([H])([H])[C@]1(OO[C@@]2(C1([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])[H]
[H]N(C(=O)C([H])([H])[C@]1(OO[C@@]2(C1([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])N(C([H])([H])[H])C([H])([H])[H]
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[H]N(C(=O)C([H])([H])[C@@]1(OO[C@@]2(C1([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C(=O)OC([H])([H])[H]
[H]O[C@]([H])(C([H])([H])N([H])C([H])([H])C1=C([H])C([H])=C([H])C(=C1[H])C(F)(F)F)[C@@]([H])(N([H])C(=O)C1=C([H])C(=C([H])C(=C1[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])N(C1=C([H])C([H])=C([H])C([H])=C1[H])S(=O)(=O)C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C1=NC([H])=C([H])C(=C1[H])C([H])([H])N1C([H])([H])C([H])([H])C([H])(C(=O)N2C([H])([H])C([H])([H])C([H])(N3C(=O)N(C4=C3C([H])=C([H])C([H])=C4[H])C([H])([H])C3=C([H])C([H])=C([H])C([H])=C3Cl)C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]C1=NC([H])=C([H])C(=C1[H])C([H])([H])N1C([H])([H])C([H])([H])C([H])(C(=O)N2C([H])([H])C([H])([H])C([H])(N3C(=O)N(C4=C3C([H])=C([H])C([H])=C4[H])C([H])([H])C3=C([H])C([H])=C([H])C([H])=C3[H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]C1=NC([H])=C([H])C(=C1[H])C([H])([H])N1C([H])([H])C([H])([H])C([H])(C(=O)N2C([H])([H])C([H])([H])C([H])(N3C(=O)N(C4=C3C([H])=C([H])C([H])=C4[H])C([H])([H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]C1=NC([H])=C([H])C(=C1[H])C([H])([H])N1C([H])([H])C([H])([H])C([H])(C(=O)N2C([H])([H])C([H])([H])C([H])(N3C(=O)N(C4=C3C([H])=C([H])C([H])=C4[H])C([H])([H])C([H])([H])N3C([H])([H])C([H])([H])C([H])([H])C([H])([H])C3([H])[H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
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[H]N(C(=O)C(OC1=C([H])C([H])=C(C([H])=N1)C(F)(F)F)(C([H])([H])[H])C([H])([H])[H])[C@@]([H])(C([H])([H])[H])[C@]([H])(C1=C([H])C([H])=C([H])C(C#N)=C1[H])C([H])([H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]C1=NN(C([H])=N1)C([H])([H])C1=C(N(N=C1C1=NN=C(S1)C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1Cl)C1=C([H])C([H])=C(Br)C([H])=C1[H]
[H]C1=NN(C([H])=N1)C([H])([H])C1=C(N(N=C1C1=NN=C(S1)C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C(Cl)C([H])=C1Cl)C1=C([H])C([H])=C(Br)C([H])=C1[H]
[H]C1=NN(C([H])=N1)C([H])([H])C1=C(N(N=C1C1=NN=C(S1)C1(C([H])([H])C([H])([H])C1([H])[H])C(F)(F)F)C1=C([H])C([H])=C(Cl)C([H])=C1Cl)C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]N1C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])[C@@]([H])(C1=C([H])C([H])=C(F)C([H])=C1[H])C([H])([H])C1=C(OC(F)(F)F)C([H])=C([H])C([H])=C1[H]
[H]O[C@@]1([H])C([H])([H])C([H])([H])N([H])[C@]1([H])C(=O)N([H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NOC(=N1)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]O[C@@]1([H])C([H])([H])C([H])([H])N([H])[C@]1([H])C(=O)N([H])[C@]([H])(C1=C([H])C([H])=C(C([H])=C1[H])C1=NOC(=N1)C([H])([H])C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])[H]
[H]O[C@@]1([H])C([H])([H])C([H])([H])N([H])[C@]1([H])C(=O)N([H])[C@]([H])(C1=C([H])C([H])=C(C([H])=C1[H])C1=NOC(=N1)C([H])([H])C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C([H])([H])[H]
[H]OC([H])([H])C1=C(SC2=C(C([H])=C([H])C([H])=C2[H])C([H])([H])N([H])C(=O)C([H])([H])[C@@]2(OO[C@@]3(C2([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C3([H])[H])C([H])([H])[H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)C([H])([H])[C@]1(OO[C@@]2(C1([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C2C(OC([H])([H])C2([H])[H])=C1[H]
[H]N(C(=O)C([H])([H])[C@@]1(OO[C@@]2(C1([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C2OC([H])([H])C([H])([H])OC2=C1[H]
[H]N(C(=O)C([H])([H])[C@@]1(OO[C@@]2(C1([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C2=C(OC([H])=C([H])C([H])([H])O2)C([H])=C1[H]
[H]N(C(=O)C([H])([H])[C@@]1(OO[C@@]2(C1([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])[H])C([H])([H])C1=NC([H])=C([H])C([H])=C1[H]
[H]N(C(=O)C([H])([H])[C@@]1(OO[C@@]2(C1([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=NC([H])=C1[H]
[H]N(C(=O)C([H])([H])[C@]1(OO[C@@]2(C1([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)C([H])([H])[C@]1(OO[C@@]2(C1([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C(OC([H])([H])[H])=C([H])C([H])=C1[H]
[H]N(C(=O)C([H])([H])[C@@]1(OO[C@@]2(C1([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])[H])C([H])([H])C1=C(OC([H])([H])C([H])([H])[H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)C([H])([H])[C@]1(OO[C@@]2(C1([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C(OC([H])([H])[H])=C([H])C(OC([H])([H])[H])=C1[H]
[H]N(C(=O)C([H])([H])[C@]1(OO[C@@]2(C1([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C(OC([H])([H])[H])=C1[H]
[H]N(C(=O)C([H])([H])[C@@]1(OO[C@@]2(C1([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C(=C([H])C([H])=C1[H])C(F)(F)F
[H]N(C(=O)C([H])([H])[C@@]1(OO[C@@]2(C1([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(OC([H])(F)F)C([H])=C1[H]
[H]C1=NC(=C(O1)C1=NN=C(SC([H])([H])C([H])([H])C([H])([H])N2C([H])([H])C3([H])C([H])([H])C3(C3=C([H])C([H])=C(C([H])=C3[H])S(F)(F)(F)(F)F)C2([H])[H])N1C([H])([H])[H])C([H])([H])[H]
[H]C1=NC(=C(O1)C1=NN=C(SC([H])([H])C([H])([H])C([H])([H])N2C([H])([H])C3([H])C([H])([H])C3(C3=C([H])C([H])=C([H])C(=C3[H])S(F)(F)(F)(F)F)C2([H])[H])N1C([H])([H])[H])C([H])([H])[H]
[H]C1=NC([H])=C([H])C(=C1[H])C([H])([H])N1C([H])([H])C([H])([H])C([H])(C(=O)N2C([H])([H])C([H])([H])C([H])(N3C(=O)N(C4=C3C([H])=C([H])C([H])=C4[H])C([H])([H])C3=C([H])C(OC([H])([H])[H])=C([H])C([H])=C3[H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]C1=NC([H])=C([H])C(=C1[H])C([H])([H])N1C([H])([H])C([H])([H])C([H])(C(=O)N2C([H])([H])C([H])([H])C([H])(N3C(=O)N(C4=C3C([H])=C([H])C([H])=C4[H])C([H])([H])C3=C([H])C([H])=C(Cl)C([H])=C3[H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]C1=NC([H])=C([H])C(=C1[H])C([H])([H])N1C([H])([H])C([H])([H])C([H])(C(=O)N2C([H])([H])C([H])([H])C([H])(N3C(=O)N(C4=C3C([H])=C([H])C([H])=C4[H])C([H])([H])C3=C([H])C(Cl)=C([H])C([H])=C3[H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]N1C([H])=C([H])C2=C([H])C(=C([H])C(F)=C12)C(=O)[C@]1(C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])N([H])C([H])([H])C1([H])[H]
[H]N1C([H])=C([H])C2=C([H])C(=C([H])C(F)=C12)C(=O)[C@]1(C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])N([H])C([H])([H])C1([H])[H]
[H]N1C([H])=C([H])C2=C([H])C(=C([H])C(F)=C12)C(=O)[C@]1(C([H])([H])OC([H])([H])C([H])([H])[H])C([H])([H])N([H])C([H])([H])C1([H])[H]
[H]N1C([H])=C([H])C2=C([H])C(=C([H])C(F)=C12)C(=O)[C@]1(C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])N([H])C([H])([H])C1([H])[H]
[H]N1C([H])=C([H])C2=C([H])C(=C([H])C(F)=C12)C(=O)[C@]1(C([H])([H])C([H])([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])N([H])C([H])([H])C1([H])[H]
[H]N1C([H])([H])C([H])([H])[C@](C(=O)C2=C([H])C([H])=C(Cl)C(Cl)=C2[H])(C([H])([H])C([H])([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C1([H])[H]
[H]N1C([H])([H])C([H])([H])[C@](C(=O)C2=C([H])C([H])=C(Cl)C(Cl)=N2)(C([H])([H])C([H])([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C1([H])[H]
[H]N([H])C1=C([H])C([H])=C(C([H])=C1Cl)C(=O)[C@@]1(C([H])([H])C([H])([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])N([H])C([H])([H])C1([H])[H]
[H]N1C([H])([H])C([H])([H])[C@](C(=O)C2=C([H])C([H])=C3C([H])=C([H])C([H])=C([H])C3=N2)(C([H])([H])C([H])([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C1([H])[H]
[H]N1C([H])([H])C([H])([H])[C@](C(=O)C2=C([H])C([H])=C3C(=N2)C([H])=C([H])C([H])=C3C([H])([H])[H])(C([H])([H])C([H])([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C1([H])[H]
[H]N1C([H])=C([H])C2=C([H])C(=C([H])C([H])=C12)C(=O)[C@@]1(N([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]N1C([H])=C([H])C2=C([H])C(=C([H])C(F)=C12)C(=O)[C@@]1(N([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]N1C([H])([H])C([H])([H])C([H])([H])[C@@]1(C(=O)C1=C([H])C([H])=C(Cl)C(Cl)=C1[H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]N([H])C1=C([H])C([H])=C(C([H])=C1Cl)C(=O)[C@@]1(N([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]N1N=C([H])C2=C([H])C(=C([H])C([H])=C12)C(=O)[C@@]1(N([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C([H])([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C(C([H])=C1[H])[C@]([H])(N1C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C1([H])[H])C1([H])C([H])([H])C([H])([H])C1([H])[H])C1=NN=NN1C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1N=NN=C1[C@@]([H])(N1C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C1([H])[H])C1([H])C([H])([H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H]
[H]C1=NN(C([H])=N1)C1=C([H])C([H])=C(C([H])=C1[H])[C@]([H])(N1C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C1([H])[H])C1([H])C([H])([H])C([H])([H])C1([H])[H])C1=NN=NN1C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C1=C([H])C2=C([H])C(=C([H])C([H])=C2O1)[C@]([H])(N1C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C1([H])[H])C1([H])C([H])([H])C([H])([H])C1([H])[H])C1=NN=NN1C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C1=NN(C([H])=N1)C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])[C@]([H])(N1C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C1([H])[H])C1([H])C([H])([H])C([H])([H])C1([H])[H])C1=NN=NN1C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)C([H])([H])[C@@]1(OO[C@@]2(C1([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])N([H])C1=C2C([H])=C([H])C(Cl)=C([H])C2=NC([H])=C1[H]
[H]C1=C2N(C(=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])N(C2=O)C1=C(C([H])=C([H])C([H])=C1[H])C(=O)N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
CC1=C2COC3=C(CCN4CCN(CC4)C4=C5C=CC(C)=NC5=CC=C4)C=CC=C3N2N=N1
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[H]N1C([H])([H])C([H])([H])[C@]2(C3=C([H])C(Cl)=C(Cl)C([H])=C3[H])C([H])([H])[C@]2(C2=NC(=C([H])S2)C([H])([H])[H])C1([H])[H]
[H]N1C([H])([H])C([H])([H])[C@]2(C3=C([H])C(Cl)=C(Cl)C([H])=C3[H])C([H])([H])[C@]2(C([H])([H])N2N=C(C([H])=C2C([H])([H])[H])C([H])([H])[H])C1([H])[H]
[H]N([H])[C@@]1([H])C([H])([H])N(C2=C([H])C3=C(N2C([H])([H])C2=C(C#N)C([H])=C([H])C(F)=C2[H])C(=O)N(C(=O)N3C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(C1=C([H])C([H])=C(C([H])=C1[H])[C@]([H])(N1N=C([H])N=C1[H])C(C(=O)OC([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C1=C([H])C2=C([H])C([H])=C([H])C([H])=C2C([H])=C1[H]
[H]N([H])C(C(=O)N1C([H])([H])C2=NC(=C(N([H])C3=C([H])C([H])=C(F)C(F)=C3[H])N2C([H])([H])C1([H])[H])C1=C([H])C([H])=C(F)C([H])=C1[H])(C([H])([H])[H])C([H])([H])[H]
[H]N([H])C(C(=O)N1C([H])([H])C2=NC(=C(N([H])C3=C([H])C([H])=C(F)C([H])=C3[H])N2C([H])([H])C1([H])[H])C1=C([H])C([H])=C(F)C([H])=C1[H])(C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])C(=C([H])C(Cl)=C1Cl)[C@]12C([H])([H])N(C([H])([H])[H])C([H])([H])[C@@]1([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H]
[H]N1C([H])([H])[C@]2([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@]2(C2=C([H])C(Cl)=C(Cl)C([H])=C2[H])C1([H])[H]
[H]C1=C([H])C(=C([H])C(Cl)=C1Cl)[C@]12C([H])([H])N(C([H])([H])C([H])([H])[H])C([H])([H])[C@@]1([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H]
[H]C1=C([H])C([H])=C2C([H])=C(C([H])=C([H])C2=C1[H])[C@@]12C([H])([H])N(C([H])([H])[H])C([H])([H])[C@]1([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H]
[H]N(C(=O)C1=C(N(C(=N1)C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])N1N=C([H])N=C1[H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C([H])C([H])=C([H])C(Cl)=C2C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N(C(=O)C1=C(N(C(=N1)C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C([H])C([H])=C([H])C(Cl)=C2C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N([H])C([H])([H])C1=C([H])C([H])=C([H])C(=C1[H])C1([H])C([H])([H])C([H])([H])N(C(=O)C2=C(C(Br)=C(OC([H])([H])C([H])([H])C([H])([H])[H])S2)C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N([H])C([H])([H])C1=C([H])C([H])=C(F)C(=C1[H])[C@]1([H])C([H])([H])C2([H])N(C(=O)C3=C(C(Br)=C(OC([H])([H])C([H])([H])C([H])([H])[H])S3)C([H])([H])[H])[C@@]([H])(C([H])([H])C2([H])[H])C1([H])[H]
[H]N(C1=C([H])C(OC([H])([H])[H])=C2N=NN(C2=N1)C1=C([H])C([H])=C([H])C(OC(F)(F)F)=C1[H])C([H])([H])C1([H])C([H])([H])C([H])([H])N([H])C([H])([H])C1([H])[H]
[H]N1C2=NC(=C([H])C([H])=N2)C2=C([H])C(OC([H])([H])C([H])([H])\C([H])=C([H])\C([H])([H])N(C([H])([H])[H])C([H])([H])C3=C([H])C1=C([H])C([H])=C3[H])=C([H])C([H])=C2[H]
[H]N1C(=C([H])C2=C1C([H])=C([H])C(Cl)=C2[H])C(=O)N1C2=C([H])C([H])=C([H])C([H])=C2[C@@]2(C1([H])[H])C([H])([H])N(C([H])([H])C2([H])[H])[C@@]1([H])C([H])([H])N([H])C([H])([H])C1([H])[H]
[H]N1C(=C([H])C2=C1C([H])=C(F)C([H])=C2[H])C(=O)N1C2=C([H])C([H])=C([H])C([H])=C2[C@@]2(C1([H])[H])C([H])([H])N(C([H])([H])C2([H])[H])[C@@]1([H])C([H])([H])N([H])C([H])([H])C1([H])[H]
[H]N1C2=C([H])C([H])=C([H])C([H])=C2C(=O)C(=C1C([H])([H])OC1=C([H])C([H])=C([H])C(OC([H])([H])C([H])([H])C([H])([H])C(F)(F)F)=C1[H])C([H])([H])[H]
[H]N1C2=C([H])C([H])=C([H])C([H])=C2C(=O)C(=C1C([H])([H])OC1=C([H])C([H])=C([H])C(OC([H])([H])C([H])([H])C(OC([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])=C1[H])C([H])([H])[H]
[H]N1C2=C([H])C([H])=C([H])C([H])=C2C(=O)C(=C1C([H])([H])OC1=C([H])C([H])=C([H])C(OC([H])([H])C2([H])C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])=N1)C([H])([H])[H]
[H]N1C2=C([H])C([H])=C([H])C([H])=C2C(=O)C(=C1C([H])([H])OC1=C([H])C([H])=C([H])C(OC([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])=C1[H])C([H])([H])[H]
[H]N1C2=C([H])C([H])=C([H])C([H])=C2C(=O)C(=C1C([H])([H])C(\[H])=C(/[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])[H]
[H]N1C2=C([H])C([H])=C([H])C([H])=C2C(=O)C(=C1C([H])([H])OC1=C([H])C([H])=C([H])C(OC([H])([H])C2([H])C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])=C1[H])C([H])([H])[H]
[H]N1C2=C([H])C([H])=C(C([H])=C2C(=O)C(=C1C([H])([H])OC1=C([H])C([H])=C([H])C(OC([H])([H])C2([H])C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])=C1[H])C([H])([H])[H])C1=C([H])N=C([H])C([H])=C1[H]
[H]N([H])C([H])([H])C1=C([H])SC(=N1)N([H])C(=O)C1=C([H])C(=NN1C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]C1=C(OC2([H])C([H])([H])C([H])([H])S(=O)(=O)C([H])([H])C2([H])[H])C([H])=C2C(OC3(C([H])([H])C([H])([H])N(C([H])([H])C3([H])[H])C3([H])C([H])([H])C([H])([H])C3([H])[H])C([H])([H])C2([H])[H])=C1[H]
[H]C1=C([H])C([H])=C2N(C(=NC2=C1[H])[C@]1([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]C1=C([H])C([H])=C2N(C(=NC2=C1[H])[C@]1([H])C([H])([H])N(C([H])([H])C(=O)N(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]C1=C([H])C([H])=C2N(C(=NC2=C1[H])[C@]1([H])C([H])([H])N(C([H])([H])C(=O)N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]C1=C([H])C([H])=C2N(C(=NC2=C1[H])[C@]1([H])C([H])([H])N(C([H])([H])C(=O)N2C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]OC([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])[C@]([H])(C2=NC3=C([H])C([H])=C([H])C([H])=C3N2C([H])([H])C2=C([H])C([H])=C(F)C([H])=C2[H])C1([H])[H]
[H]OC(=O)C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C1=C(SC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C2=C([H])C(OC([H])([H])C3=C([H])C([H])=C(C([H])=N3)C([H])([H])[H])=C([H])C([H])=C2N1C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C(C([H])=N1)C([H])([H])[H]
[H]OC(=O)C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C1=C(SC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C2=C([H])C(OC([H])([H])C3=C([H])C([H])=C(C([H])=N3)C([H])([H])[H])=C([H])C([H])=C2N1C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C(F)C([H])=N1
[H]C1=C([H])C([H])=C(OC([H])([H])C([H])([H])N2C3=C([H])C([H])=C([H])C([H])=C3N=C2[C@]2([H])C([H])([H])N(C([H])([H])C(=O)N(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C2([H])[H])C([H])=C1[H]
[H]N1C([H])([H])C([H])([H])O[C@]([H])(C2=NC3=C([H])C([H])=C([H])C([H])=C3N2C([H])([H])C2=C([H])C(=C(C([H])=C2[H])C([H])([H])[H])C([H])([H])[H])C1([H])[H]
[H]N1C([H])([H])C([H])([H])S[C@]([H])(C2=NC3=C([H])C([H])=C([H])C([H])=C3N2C([H])([H])C2=C([H])C([H])=C(C([H])=C2[H])C([H])([H])[H])C1([H])[H]
[H]N1C([H])([H])C([H])([H])S[C@@]([H])(C2=NC3=C([H])C([H])=C([H])C([H])=C3N2C([H])([H])C2=C([H])C([H])=C(OC([H])([H])[H])C([H])=C2[H])C1([H])[H]
[H]N(C1=NC(=C([H])S1)C1=C([H])C([H])=C([H])C([H])=N1)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])S(=O)(=O)N(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)N([H])[C@]([H])(C([H])([H])[H])C([H])([H])[C@@]([H])(N([H])C(=O)C([H])([H])[H])N1C([H])([H])C([H])([H])C([H])([H])[C@@]([H])(C([H])([H])C2=C([H])C([H])=C(F)C([H])=C2[H])C1([H])[H])C1=C([H])C(=C([H])C([H])=C1[H])C1=NN=NN1C([H])([H])[H]
[H]N([H])[C@@]([H])(N1C([H])([H])C([H])([H])C([H])([H])[C@@]([H])(C([H])([H])C2=C([H])C([H])=C(F)C([H])=C2[H])C1([H])[H])C([H])([H])[C@]([H])(N([H])C(=O)N([H])C1=C([H])C(=C([H])C([H])=C1[H])C1=NN=NN1C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)N([H])[C@]([H])(C([H])([H])[H])C([H])([H])[C@@]([H])(OC(=O)N([H])C([H])([H])[H])N1C([H])([H])C([H])([H])C([H])([H])[C@@]([H])(C([H])([H])C2=C([H])C([H])=C(F)C([H])=C2[H])C1([H])[H])C1=C([H])C(=C([H])C([H])=C1[H])C1=NN=NN1C([H])([H])[H]
[H]O[C@@]([H])(N1C([H])([H])C([H])([H])C([H])([H])[C@@]([H])(C([H])([H])C2=C([H])C([H])=C(F)C([H])=C2[H])C1([H])[H])C([H])([H])[C@]([H])(N([H])C(=O)N([H])C1=C([H])C(=C([H])C([H])=C1[H])C1=NN=NN1C([H])([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]O[C@@]([H])(N1C([H])([H])C([H])([H])C([H])([H])[C@@]([H])(C([H])([H])C2=C([H])C([H])=C(F)C([H])=C2[H])C1([H])[H])C([H])([H])[C@]([H])(N([H])C(=O)N([H])C1=C([H])C(=C([H])C([H])=C1[H])C1=NN=NN1C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]O[C@@]([H])(N1C([H])([H])C([H])([H])C([H])([H])[C@@]([H])(C([H])([H])C2=C([H])C([H])=C(F)C([H])=C2[H])C1([H])[H])C([H])([H])[C@]([H])(N([H])C(=O)N([H])C1=C([H])C(=C([H])C(=C1[H])C1=NOC([H])=C1[H])C1=NOC([H])=C1[H])C([H])([H])[H]
[H]O[C@@]([H])(N1C([H])([H])C([H])([H])C([H])([H])[C@@]([H])(C([H])([H])C2=C([H])C([H])=C(F)C([H])=C2[H])C1([H])[H])C([H])([H])[C@]([H])(N([H])C(=O)N([H])C1=C([H])C(=C([H])C(=C1[H])C1=NC([H])=C([H])O1)C1=NC([H])=C([H])O1)C([H])([H])[H]
[H]O[C@@]([H])(N1C([H])([H])C([H])([H])C([H])([H])[C@@]([H])(C([H])([H])C2=C([H])C([H])=C(F)C([H])=C2[H])C1([H])[H])C([H])([H])[C@]([H])(N([H])C(=O)N([H])C1=C([H])C(=C([H])C(=C1[H])N1N=NC([H])=C1[H])N1N=NC([H])=C1[H])C([H])([H])[H]
[H]N(C(=O)N([H])[C@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])[C@@]([H])(C([H])([H])C2=C([H])C([H])=C(F)C([H])=C2[H])C1([H])[H])C1=C([H])C(=C([H])C(=C1[H])N1N=NC([H])=C1[H])N1N=NC([H])=C1[H]
[H]O[C@@]([H])(N1C([H])([H])C([H])([H])C([H])([H])[C@@]([H])(C([H])([H])C2=C([H])C([H])=C(F)C([H])=C2[H])C1([H])[H])C([H])([H])[C@]([H])(N([H])C(=O)N([H])C1=C([H])C(=C([H])C(=C1[H])C1=NC([H])=C([H])S1)C1=NC([H])=C([H])S1)C([H])([H])[H]
[H]O[C@@]([H])(N1C([H])([H])C([H])([H])C([H])([H])[C@@]([H])(C([H])([H])C2=C([H])C([H])=C(F)C([H])=C2[H])C1([H])[H])C([H])([H])[C@]([H])(N([H])C(=O)N([H])C1=C([H])C(=C([H])C([H])=C1[H])C1=NC([H])=C([H])N1C([H])([H])[H])C([H])([H])[H]
[H]O[C@@]([H])(N1C([H])([H])C([H])([H])C([H])([H])[C@@]([H])(C([H])([H])C2=C([H])C([H])=C(F)C([H])=C2[H])C1([H])[H])C([H])([H])[C@]([H])(N([H])C(=O)N([H])C1=C([H])C(=C([H])C(=C1[H])N1N=C([H])C([H])=C1[H])N1N=C([H])C([H])=C1[H])C([H])([H])[H]
[H]O[C@@]([H])(N1C([H])([H])C([H])([H])C([H])([H])[C@@]([H])(C([H])([H])C2=C([H])C([H])=C(F)C([H])=C2[H])C1([H])[H])C([H])([H])[C@]([H])(N([H])C(=O)N([H])C1=C([H])C(=C([H])C(=C1[H])C([H])(C([H])([H])[H])C([H])([H])[H])C1=NN=NN1C([H])([H])[H])C([H])([H])[H]
[H]O[C@@]([H])(N1C([H])([H])C([H])([H])C([H])([H])[C@@]([H])(C([H])([H])C2=C([H])C([H])=C(F)C([H])=C2[H])C1([H])[H])C([H])([H])[C@]([H])(N([H])C(=O)N([H])C1=C([H])C(=C([H])C(=C1[H])C([H])([H])[H])C1=NN=NN1C([H])([H])[H])C([H])([H])[H]
[H]O[C@@]([H])(N1C([H])([H])C([H])([H])C([H])([H])[C@@]([H])(C([H])([H])C2=C([H])C([H])=C(F)C([H])=C2[H])C1([H])[H])C([H])([H])[C@]([H])(N([H])C(=O)N([H])C1=C([H])C(=C([H])C(Br)=C1[H])C1=NN=NN1C([H])([H])[H])C([H])([H])[H]
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[H]OC1=C(OC([H])([H])[C@]([H])(N2N=NN=C2[C@]([H])(N([H])C(=O)C(N([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])OC([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C#N)C([H])=C([H])C([H])=C1[H]
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[H]N(C(=O)N([H])[C@]([H])(C([H])([H])[H])C([H])([H])[C@@]([H])(N(C([H])([H])[H])C([H])([H])[H])N1C([H])([H])C([H])([H])C([H])([H])[C@@]([H])(C([H])([H])C2=C([H])C([H])=C(F)C([H])=C2[H])C1([H])[H])C1=C([H])C(=C([H])C(=C1[H])C([H])([H])C([H])([H])[H])C1=NN=NN1C([H])([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C([H])C2=C([H])C(OC3=C4C([H])=C(OC([H])([H])[H])C(OC([H])([H])[H])=C([H])C4=NC([H])=C3[H])=C([H])C([H])=C12)C1=C([H])C([H])=NC([H])=C1[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])[C@]1([H])C([H])([H])C([H])([H])C([H])([H])N(C(=O)C([H])([H])N2C(=O)SC3=C2C([H])=C(Cl)C([H])=C3[H])[C@@]1([H])C([H])([H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])[C@]1([H])C([H])([H])C([H])([H])C([H])([H])N(C(=O)C([H])([H])N2C(=O)SC3=C2C([H])=C(Cl)C([H])=C3[H])[C@@]1([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
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[H]C1=C([H])C([H])=C(C([H])=C1[H])[C@]1([H])C([H])([H])C([H])([H])C([H])([H])N(C(=O)C([H])([H])N2C(=O)C([H])=NC3=C2C([H])=C(C(=C3[H])C([H])([H])[H])C([H])([H])[H])[C@@]1([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])[C@]1([H])C([H])([H])C([H])([H])C([H])([H])N(C(=O)C([H])([H])N2C(=O)C([H])=NC3=C2C([H])=C(Cl)C(Cl)=C3[H])[C@@]1([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])[C@]1([H])C([H])([H])C([H])([H])C([H])([H])N(C(=O)C([H])([H])N2C3=C(OC([H])([H])C2=O)C([H])=C(C(=C3[H])C([H])([H])[H])C([H])([H])[H])[C@@]1([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])[C@]1([H])C([H])([H])C([H])([H])C([H])([H])N(C(=O)C([H])([H])N2C3=C(OC([H])([H])C2=O)C([H])=C(Cl)C(Cl)=C3[H])[C@@]1([H])C([H])([H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
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[H]N([H])C1=C(Cl)C([H])=C(C(=O)N([H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H])C(OC([H])([H])[H])=C1[H]
[H]N1C2=C(C([H])=C([H])C([H])=C2[H])C2=C1[C@@]1([H])N(C([H])([H])C2([H])[H])C([H])([H])[C@]2([H])[C@@]([H])(OC([H])=C(C(=O)OC([H])([H])[H])[C@@]2([H])C1([H])[H])C([H])([H])[H]
[H]C1=C([H])C(=C([H])C2=C1OC([H])([H])C2([H])[H])C([H])([H])[C@@]([H])(N(C([H])([H])C([H])([H])[H])C([H])([H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])S(=O)(=O)C([H])([H])[H])C([H])([H])[H]
[H]N1C(=NC(=C1C([H])([H])N1C([H])([H])C([H])([H])N(C2=C([H])C(=C([H])C([H])=N2)C(F)(F)F)C([H])([H])C1([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C1=NC([H])([H])C(=N1)C([H])([H])N1C([H])([H])C([H])([H])N(C2=NC([H])=C(F)C([H])=N2)C([H])([H])C1([H])[H]
[H]OC(=O)[C@]([H])(OC1=C([H])C([H])=C(C(=C1C([H])([H])[H])C([H])([H])[H])S(=O)(=O)N(C1=C([H])C([H])=C([H])C(=C1Cl)C1=C([H])C([H])=C(OC(F)(F)F)C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])[H]
[H]OC(=O)[C@]([H])(OC1=C([H])C([H])=C(C(=C1C([H])([H])[H])C([H])([H])[H])S(=O)(=O)N(C1=C([H])C([H])=C([H])C(=C1Cl)C1=C([H])C([H])=C(C([H])=C1[H])C(F)(F)F)C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])[H]
[H]C1=C(Cl)C(Cl)=C([H])C(=C1[H])[C@]1(C([H])([H])OC([H])([H])C([H])([H])[H])[C@@]2([H])C([H])([H])C([H])([H])C([H])([H])[C@@]12[H]
[H]N1C([H])([H])[C@@]2([H])[C@]([H])(C([H])([H])OC([H])([H])C([H])([H])[H])[C@@]2(C([H])([H])[H])C1([H])[H]
[H]N(C(=O)C([H])([H])C1=NC([H])=C(OC2=C([H])C([H])=NC3=C([H])C(OC([H])([H])C([H])([H])[H])=C(OC([H])([H])[H])C([H])=C23)C([H])=C1OC([H])([H])[H])C1=NN([H])C(=C1C([H])([H])[H])C([H])([H])C([H])([H])[H]
[H]N(C(=O)[C@@]1([H])N(C(=O)C([H])([H])C2=C([H])N=C([H])N2[H])C([H])([H])[C@]([H])(C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C1([H])[H])C1=C([H])C([H])=C(OC2=C([H])C([H])=C(F)C([H])=C2[H])C([H])=C1[H]
[H]N(C(=O)[C@@]1([H])N(C(=O)C([H])([H])C2=C([H])N=C([H])N2[H])C([H])([H])[C@]([H])(C2=C([H])C([H])=C([H])C([H])=C2[H])C1([H])[H])C1=C([H])C([H])=C(OC2=C([H])C([H])=C(F)C([H])=C2[H])C([H])=C1[H]
[H]N(C(=O)[C@@]1([H])N(C(=O)C([H])([H])N2N=C([H])N=C2[H])C([H])([H])[C@]([H])(C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C1([H])[H])C1=C([H])C([H])=C(OC2=C([H])C([H])=C(F)C([H])=C2[H])C([H])=C1[H]
[H]N(C(=O)[C@@]1([H])N(C(=O)C([H])([H])N2N=C([H])N=C2[H])C([H])([H])[C@]([H])(C([H])([H])C2=C([H])C([H])=C(F)C([H])=C2[H])C1([H])[H])C1=C([H])C([H])=C(OC2=C([H])C([H])=C(F)C([H])=C2[H])C([H])=C1[H]
[H]N([H])[C@]([H])(C1=C(N=C(O1)C1=C2C([H])=C([H])C(=NC2=C(OC([H])([H])[H])C([H])=C1[H])C(F)(F)F)C(=O)N([H])C([H])([H])C1=C([H])C([H])=C(F)C([H])=C1F)C([H])([H])[H]
[H]N([H])C([H])([H])C([H])([H])C([H])([H])C(C1=C([H])C([H])=C([H])C([H])=C1[H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C(=C1[H])C([H])([H])[H]
[H]N1C(SC([H])([H])C([H])([H])[H])=NC2=C1C([H])=C([H])C(OC([H])([H])[H])=C2[H]
[H]N1C(SC([H])([H])C([H])([H])C([H])([H])[H])=NC2=C1C([H])=C([H])C(OC([H])([H])[H])=C2[H]
[H]N1C(SC([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])=NC2=C1C([H])=C([H])C(OC([H])([H])[H])=C2[H]
[H]OC([H])([H])C([H])([H])C([H])([H])SC1=NC2=C(N1[H])C([H])=C([H])C(OC([H])([H])[H])=C2[H]
[H]N1C(SC([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])=NC2=C1C([H])=C([H])C(OC([H])([H])[H])=C2[H]
[H]N1C(SC([H])([H])C2=C([H])C([H])=C(C([H])=C2[H])C([H])([H])[H])=NC2=C1C([H])=C([H])C(OC([H])([H])[H])=C2[H]
[H]N1C(SC([H])([H])C2=C([H])C([H])=C(C([H])=C2[H])C([H])(C([H])([H])[H])C([H])([H])[H])=NC2=C1C([H])=C([H])C(OC([H])([H])[H])=C2[H]
[H]N1C(SC([H])([H])C2=C([H])C([H])=C(C([H])=C2[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])=NC2=C1C([H])=C([H])C(OC([H])([H])[H])=C2[H]
[H]N1C(SC([H])([H])C2=C([H])C([H])=C(Cl)C([H])=C2[H])=NC2=C1C([H])=C([H])C(OC([H])([H])[H])=C2[H]
[H]N1C(SC([H])([H])C2=C([H])C([H])=C(Br)C([H])=C2[H])=NC2=C1C([H])=C([H])C(OC([H])([H])[H])=C2[H]
[H]N1C(SC([H])([H])C2=C([H])C(OC([H])([H])[H])=C([H])C(OC([H])([H])[H])=C2[H])=NC2=C([H])C([H])=C(OC([H])([H])[H])C([H])=C12
[H]N1C(SC([H])([H])C2=C([H])C([H])=C([H])C(=C2[H])C2=C([H])C([H])=C([H])C([H])=C2[H])=NC2=C1C([H])=C([H])C(OC([H])([H])[H])=C2[H]
[H]N1C(SC([H])([H])C2=C([H])C([H])=C3C([H])=C([H])C([H])=C([H])C3=C2[H])=NC2=C([H])C([H])=C(OC([H])([H])[H])C([H])=C12
[H]N1C(SC([H])([H])C2=C([H])C([H])=C([H])C(OC3=C([H])C([H])=C([H])C([H])=C3[H])=C2[H])=NC2=C1C([H])=C([H])C(OC([H])([H])[H])=C2[H]
[H]N1C(SC([H])([H])C2=C([H])C([H])=C(OC([H])([H])C3=C([H])C([H])=C([H])C([H])=C3[H])C([H])=C2[H])=NC2=C1C([H])=C([H])C(OC([H])([H])[H])=C2[H]
[H]N1C(SC([H])([H])C2=C([H])C([H])=C([H])C([H])=N2)=NC2=C1C([H])=C([H])C([H])=C2[H]
[H]N([H])C1=C([H])C2=C(N([H])C(SC([H])([H])C3=NC([H])=C([H])C([H])=C3[H])=N2)C([H])=C1[H]
[H]N1C(SC([H])([H])C2=C([H])C([H])=C(I)C([H])=C2[H])=NC2=C1C([H])=C([H])C(OC([H])([H])[H])=C2[H]
CC1=CC(N[C@H](CCCCNCC2=CC=C(F)C=C2)C(=O)NO)=CC(C)=C1F
[H]ON([H])C(=O)[C@@]([H])(C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])C([H])([H])C1=C([H])C([H])=C(F)C([H])=C1[H])C([H])([H])[C@@]([H])(OC([H])([H])[H])C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]ON([H])C(=O)[C@]([H])(OC1=C([H])C(=C(F)C(=C1[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])[C@]([H])(C1=C([H])C([H])=C(F)C([H])=C1[H])C([H])([H])C([H])([H])[H]
[H]ON([H])C(=O)[C@]([H])(N([H])C1=C([H])C(=C(F)C(=C1[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])[C@]([H])(C1=C([H])C([H])=C(F)C([H])=C1[H])C([H])([H])C([H])([H])[H]
[H]ON([H])C(=O)[C@]([H])(OC1=C([H])C(=C(F)C(=C1[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])C([H])([H])C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]ON([H])C(=O)[C@@]([H])(C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])[C@@]([H])(C1=C([H])C([H])=C(F)C([H])=C1[H])C([H])([H])C([H])([H])[H])C([H])([H])[C@@]([H])(OC([H])([H])[H])C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]ON([H])C(=O)[C@]([H])(C([H])([H])C1=C([H])C(=C(F)C(=C1[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])[C@]([H])(C1=C([H])C([H])=C(F)C([H])=C1[H])C([H])([H])C([H])([H])[H]
[H]ON([H])C(=O)[C@]([H])(C([H])([H])C1=C([H])C(=C(F)C(=C1[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])C([H])([H])C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]N=C1N([H])[C@@]2(C3=C([H])C(=C([H])S3)C3=C([H])C(C#N)=C([H])C([H])=C3[H])C([H])([H])N(C3=NC([H])=C(F)C([H])=C3[H])C([H])([H])[C@@]2([H])C(=O)N1C([H])([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C(S1)N1C(=NC2=C1C([H])=C([H])C(OC(F)(F)F)=C2[H])C([H])([H])[H])C1([H])C([H])([H])C1([H])[H]
[H]OC1=C([H])C([H])=C2N([H])C(=NC2=C1C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N1C(=NC2=C(C([H])=C([H])C([H])=C12)C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N1C(=NC2=C(C(F)=C([H])C([H])=C12)C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C1=NC([H])=C([H])C(=C1[H])C1=NN=C(SC([H])([H])C2=NC(=NO2)C2=C([H])C([H])=C(C([H])=C2[H])C([H])([H])[H])N1C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]N(C1=NC(OC([H])([H])[H])=C(C([H])=C1[H])N1C([H])=NC(=C1[H])C([H])([H])[H])C1=C([H])C([H])=C([H])C2=C1N=C(N2C([H])([H])[H])C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]N(C(=O)N([H])C1=C([H])C([H])=C([H])C(=C1[H])C1=NN(C([H])=C1C1=C([H])C([H])=NC2=C1C([H])=C([H])N2[H])C([H])([H])C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C(F)(F)F
[H]N(C(=O)N([H])C1=C([H])C([H])=C([H])C(=C1[H])C1=NN(C([H])=C1C1=C([H])C([H])=NC2=C1C([H])=C([H])N2[H])C([H])([H])C([H])([H])[H])C1=C([H])C([H])=C([H])C(OC([H])([H])[H])=C1[H]
[H]OC1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[C@]([H])(N([H])C(=O)N([H])C1=C([H])C([H])=C(C([H])=C1[H])C(=O)OC([H])(C([H])([H])[H])C([H])([H])[H])C(=O)N([H])[C@@]1([H])C([H])([H])C([H])([H])C([H])([H])[N@@+](C([H])([H])[H])(C([H])([H])C2=C([H])C(O[H])=C([H])C([H])=C2[H])C1([H])[H]
[H]N(C1=NC([H])=C([H])C2=C1C1=C([H])C([H])=C([H])C([H])=C1N2[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
CC(C)N1C=NC2=C(NCC3=CC=C(C=C3)C3=NC=CC=C3)N=C(NC[C@@H](O)CO)N=C12
CN1[C@@H](C[C@H](O)C2=CC=CC=C2)CCC[C@H]1CC(=O)C1=CC=CC=C1
CN1N=C(C2=C1C=C(C)C=C2)C1=NC2=C(NC=C2C(=O)NC2(C)CCNC2)N=C1
CC(C)(C)NC(=O)C1=CNC2=C1N=C(C=N2)C1=NNC2=C1C=CC=C2C(C)(C)O
CN1N=C(C2=C1C=CC(CO)=C2)C1=NC2=C(NC=C2C(=O)NC(C)(C)C)N=C1
[H][C@@]12CCCO[C@]1([H])C1=CC(OCCC(C)C)=CC=C1N[C@@H]2C1CCOCC1
COC1=CC(CN(CCN(C)C)C(=O)NC2=CC=C(C=C2)C2=CNN=C2)=CC=C1
COCCN1CC=CC[C@@H](C1)C1=CC(Cl)=C(Cl)C=C1
ClC1=C(Cl)C=C(C=C1)C1CCCCNC1
C1NCC(CC=C1)C1=CC2=C(O1)C=CC=C2
FC1=C(Cl)C=C(C=C1)C1CNCC=CC1
CC1=C(Cl)C=C(C=C1)C1CNCC=CC1
C1NCC(CC=C1)C1=CC2=CC=CC=C2C=C1
ClC1=C(Cl)C=C(C=C1)[C@H]1CNCC=CC1
[H]N1C(=NC2=C([H])C([H])=C([H])C([H])=C12)C([H])([H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C([H])([H])[C@@]1(OC(=O)C([H])([H])OC([H])([H])[H])C([H])([H])C([H])([H])C2=C([H])C(F)=C([H])C([H])=C2[C@]1([H])C([H])(C([H])([H])[H])C([H])([H])[H]
CC(C)(C)NC(=O)NCCN1CCCC(C1)NC(=O)C1=CC(Cl)=CC(Cl)=C1
CC(C)(C)NC(=O)NCCN1CCC(C1)NC(=O)C1=CC(Cl)=CC(Cl)=C1
CC(C)(C)NC(=O)NCCN1CC(C1)NC(=O)C1=CC(Cl)=CC(Cl)=C1
CC(C)(C)NC(=O)NCCN1CCC(CNC(=O)C2=CC(Cl)=CC(Cl)=C2)C1
CC(C)(C)NC(=O)NCCN1CCCC(CNC(=O)C2=CC(Cl)=CC(Cl)=C2)C1
CC(C)(C)NC(=O)NCCN1CCC(CNC(=O)C2=CC(Cl)=CC(Cl)=C2)CC1
CC(C)(C)NC(=O)NCCN1CCN(CC(=O)NC2=CC(Cl)=CC(Cl)=C2)CC1
FC1=CC(=CC=C1)N1CNC(=O)C11CCN(CCNC(=O)C2=CC=C(F)C(F)=C2)CC1
C[C@@H](CN1CCC2(CC1)N(CNC2=O)C1=CC=CC(C)=C1)NC(=O)C1=CC=C(Br)C=C1
[H][C@]12C[C@](O)(CCN1CCC1=CC(OC)=C(O)C=C21)C1=CC=C(OC(F)(F)F)C=C1
[H]O[C@@]([H])(C([H])([H])OC1=C([H])C([H])=C([H])C2=C([H])C([H])=C([H])C([H])=C12)C([H])([H])[N+]([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H]