[H]SC([H])([H])[C@]([H])([N+]([H])([H])[H])C([H])([H])C1=C([H])C([H])=C2C([H])=C([H])C([H])=C([H])C2=C1[H] [H]SC([H])([H])[C@@]([H])([N+]([H])([H])[H])C([H])([H])SC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H] [H]SC([H])([H])[C@]([H])([N+]([H])([H])[H])C([H])([H])SC([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H] [H]SC([H])([H])[C@@]([H])(C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])[N+]([H])([H])C([H])([H])[H] [H]SC([H])([H])[C@]([H])(N([H])[H])C([H])([H])[S@@+]([O-])C([H])([H])[H] [H]SC([H])([H])[C@]([H])([N+]([H])([H])[H])C([H])([H])OC([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H] [H]SC([H])([H])[C@]([H])([N+]([H])([H])[H])C([H])([H])SC([H])([H])[H] [H]SC([H])([H])[C@]([H])([N+]([H])([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H] [H]SC([H])([H])[C@]([H])([N+]([H])([H])[H])C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H] [H]SC([H])([H])[C@@]([H])([N+]([H])([H])[H])C([H])([H])C([H])([H])SC([H])([H])[H] [H]SC([H])([H])[C@@]([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])[N+]([H])([H])[H] [H]SC([H])([H])[C@]([H])(N([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H] [H]OC1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[C@@]([H])([N+]([H])([H])[H])C([H])([H])S[H] [H]SC([H])([H])[C@]([H])(N([H])[H])C([H])([H])C([H])([H])[S@@+]([O-])C([H])([H])[H] [H]N([H])[C@]([H])(C(=O)C(=O)N([H])C([H])([H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H] [H]OC(=O)[C@]([H])(C([H])([H])[H])C([H])([H])[C@]([H])(N([H])[H])C([H])([H])S[H] [H]OC(=O)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[C@@]([H])(N([H])[H])C([H])([H])S[H] [H]OC(=O)C([H])([H])C([H])([H])[C@@]([H])(N([H])[H])C([H])([H])S[H] [H]OC(=O)C([H])([H])C([H])([H])[C@]([H])(N([H])C([H])([H])[H])C([H])([H])S[H] [H]OC(=O)C1=C([H])C([H])=C([H])C(=C1[H])[C@@]([H])(N([H])[H])C([H])([H])S[H] [H]OC(=O)C([H])([H])[C@@]1([H])C([H])([H])C([H])([H])[C@]([H])(C([H])([H])[C@@]([H])(N([H])[H])C([H])([H])S[H])C([H])([H])C1([H])[H] [H]OC(=O)C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[C@@]([H])(N([H])[H])C([H])([H])S[H] [H]OC(=O)C1=C([H])C([H])=C([H])C(=C1[H])C([H])([H])[C@@]([H])(N([H])[H])C([H])([H])S[H] [H]OP(=O)(O[H])C([H])([H])C([H])([H])C([H])([H])[C@@]([H])(N([H])[H])C([H])([H])S[H] [H]ON([H])C(=O)C([H])([H])C([H])([H])C([H])([H])[C@]([H])(N([H])[H])C([H])([H])S[H] [H]OC(=O)C([H])(C(=O)O[H])C([H])([H])C([H])([H])[C@@]([H])(N([H])[H])C([H])([H])S[H] [H]SC([H])([H])[C@@]([H])(N([H])[H])C([H])([H])C([H])([H])C([H])([H])S([O-])(=O)=O [H]OC(=O)C([H])([H])C([H])([H])C([H])([H])[C@]([H])(N([H])[H])C([H])([H])S[H] [H]OC(=O)C([H])(C(=O)O[H])C([H])([H])[C@@]([H])(N([H])[H])C([H])([H])S[H] [H]SC([H])([H])C([H])([H])C([H])([H])[C@]([H])(N([H])[H])C([H])([H])S[H] [H]OC(=O)[C@@]([H])(N([H])C(=O)[C@]([H])(C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[P@](=O)(O[H])[C@@]([H])([N+]([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H] [H]OC(=O)[C@@]([H])(N([H])C(=O)[C@]([H])(C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[P@](=O)(O[H])[C@]([H])([N+]([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H] [H]OC(=O)[C@@]([H])(N([H])C(=O)[C@]([H])(C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[P@@](=O)(O[H])[C@]([H])(C1=C([H])C([H])=C(C([H])=C1C([H])([H])[H])C([H])([H])[H])[N+]([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H] [H]OC(=O)[C@@]([H])(N([H])C(=O)[C@]([H])(C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])[P@@](=O)(O[H])[C@]([H])([N+]([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H] [H]OC(=O)[C@@]([H])(N([H])C(=O)[C@]([H])(C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[P@](=O)(O[H])[C@]([H])([N+]([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H] [H]OC(=O)[C@@]([H])(N([H])C(=O)[C@]([H])(C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[P@](=O)(O[H])[C@@]([H])([N+]([H])([H])[H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H] [H]OC(=O)[C@@]([H])(N([H])C(=O)[C@]([H])(C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[P@](=O)(O[H])[C@@]([H])([N+]([H])([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H] [H]OC(=O)[C@@]([H])(N([H])C(=O)[C@]([H])(C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[P@](=O)(O[H])[C@]([H])(C([H])([H])[H])[N+]([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H] [H]OC(=O)[C@@]([H])(N([H])C(=O)[C@]([H])(C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[P@](=O)(O[H])[C@@]([H])([N+]([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])[H] [H]OC(=O)[C@@]([H])(N([H])C(=O)[C@]([H])(C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[P@@](=O)(O[H])[C@]([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])[N+]([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H] [H]OC(=O)[C@@]([H])(N([H])C(=O)[C@]([H])(C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[P@](=O)(O[H])[C@]([H])(C([H])([H])[H])[N+]([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H] [H]OC(=O)[C@@]([H])(N([H])C(=O)[C@]([H])(C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[P@](=O)(O[H])[C@@]([H])(C([H])([H])[H])[N+]([H])([H])[H])C([H])([H])[H] [H]OC(=O)[C@@]([H])(N([H])C(=O)[C@]([H])(C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[P@](=O)(O[H])[C@@]([H])([N+]([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H] [H]OC(=O)[C@@]([H])(N([H])C(=O)[C@]([H])(C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])[P@](=O)(O[H])[C@]([H])(C([H])([H])[H])[N+]([H])([H])[H])C([H])([H])[H] [H]OC(=O)[C@@]([H])(N([H])C(=O)[C@]([H])(C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])[P@@](=O)(O[H])[C@]([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])[N+]([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H] [H]OC(=O)[C@@]([H])(N([H])C(=O)[C@]([H])(C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[P@](=O)(O[H])[C@@]([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])[N+]([H])([H])[H])C([H])([H])[H] [H]OC(=O)[C@@]([H])(N([H])C(=O)[C@]([H])(C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[P@](=O)(O[H])[C@@]([H])([N+]([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H] [H]OC(=O)[C@@]([H])(N([H])C(=O)[C@]([H])(C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[P@](=O)(O[H])[C@@]([H])([N+]([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H] [H]OC(=O)[C@@]([H])(N([H])C(=O)[C@]([H])(C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[P@](=O)(O[H])[C@@]([H])([N+]([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C(O[H])C([H])=C1[H] [H]OC(=O)[C@@]([H])(N([H])C(=O)[C@]([H])(C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[P@](=O)(O[H])[C@@]([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])[N+]([H])([H])[H])[C@@]([H])(O[H])C([H])([H])[H] [H]OC(=O)[C@@]([H])(N([H])C(=O)[C@]([H])(C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[P@@](=O)(O[H])[C@]([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])[N+]([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H] [H]OC(=O)[C@@]([H])(N([H])C(=O)[C@]([H])(C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[P@](=O)(O[H])[C@@]([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])[N+]([H])([H])[H])C([H])([H])O[H] [H]OC(=O)C([H])([H])N([H])C(=O)[C@]([H])(C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[P@](=O)(O[H])[C@@]([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])[N+]([H])([H])[H] [H]OC(=O)[C@@]([H])(N([H])C(=O)[C@]([H])(C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[P@@](=O)(O[H])[C@]([H])(C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H])[N+]([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H] [H]OC(=O)[C@@]([H])(N([H])C(=O)[C@]([H])(C([H])([H])C1=C([H])C([H])=C(Br)C([H])=C1[H])C([H])([H])[P@](=O)(O[H])[C@@]([H])(C([H])([H])[H])[N+]([H])([H])[H])C([H])([H])[H] [H]ON([H])C(=O)C([H])([H])C(=O)N(C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])N([H])C2=C3C([H])=C([H])C(Cl)=C([H])C3=NC([H])=C2[H])C([H])([H])C1([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H] [H]ON([H])C(=O)[C@]([H])(C(=O)N(C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])N([H])C2=C3C([H])=C([H])C(Cl)=C([H])C3=NC([H])=C2[H])C([H])([H])C1([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H] [H]ON([H])C(=O)[C@@]([H])(N([H])[H])C(=O)N(C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])N([H])C2=C3C([H])=C([H])C(Cl)=C([H])C3=NC([H])=C2[H])C([H])([H])C1([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H] [H]ON([H])C(=O)C([H])([H])SC1=C([H])C2=C(C([H])=C([H])C([H])=C2[H])C([H])=C1[H] [H]O[C@@]([H])(C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])[P@@](=O)(O[H])[C@@]([H])(N([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H] [H]O[P@@](=O)(C(=O)N([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])[C@]([H])(N([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H] [H]O[P@@](=O)([C@@]([H])(N([H])[H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])[C@]([H])(N([H])[H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H] [H]O[C@@]([H])(C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])[P@](=O)(O[H])[C@]([H])(N([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H] [H]O[P@@](=O)([C@@]([H])(N([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])[C@@]([H])(N([H])[H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H] [H]O[C@@]([H])(C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])[P@@](=O)(O[H])[C@@]([H])(N([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H] [H]OP(=O)([C@@]([H])(N([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])[C@@]([H])(N([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H] [H]O[C@@]([H])(C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])[P@](=O)(O[H])[C@]([H])(N([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H] [H]O[P@@](=O)(C(=O)N([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])[C@]([H])(N([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H] [H]O[C@@]([H])(C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])[P@@](=O)(O[H])[C@@]([H])(N([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H] [H]OC(=O)[C@@]([H])(N([H])C(=O)[C@@]1([H])N(C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C2=C([H])C([H])=C(O[H])C([H])=C2[H])[C@@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])[H])C([H])([H])C2=C([H])N=C([H])N2[H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H] [H]OC(=O)[C@@]([H])(N([H])C(=O)[C@@]1([H])N(C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)C2=C([H])C(N([H])C(=O)[C@@]([H])(N([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])=C([H])C(=C2[H])C([H])([H])C2=C([H])C([H])=C(O[H])C([H])=C2[H])[C@@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])[H])C([H])([H])C2=C([H])N=C([H])N2[H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H] [H]N([H])[C@@]([H])(C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])[C@]([H])(C#N)N([H])[C@]([H])(C(=O)N1C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C(=O)OC([H])([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H] [H]N([H])[C@@]([H])(C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])[C@]([H])(C#N)N([H])[C@]([H])(C(=O)OC([H])([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H] [H]N([H])[C@@]([H])(C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])[C@]([H])(C#N)N([H])[C@]([H])(C(=O)OC([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H] [H]N([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@]([H])(N([H])[C@@]([H])(C#N)[C@@]([H])(N([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C(=O)OC([H])([H])[H] [H]ON([H])C(=O)C([H])([H])N1C(=O)C([H])([H])C([H])([H])[C@]([H])(N([H])C(=O)C([H])([H])N([H])[H])C1=O [H]ON([H])C(=O)C([H])([H])N1C(=O)C([H])([H])C([H])([H])[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C1=O [H]ON([H])C(=O)C([H])([H])N1C(=O)C([H])([H])C([H])([H])[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])[H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C1=O [H]ON([H])C(=O)C([H])([H])N1C(=O)C([H])([H])C([H])([H])[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])[H])C1=O [H]ON([H])C(=O)C([H])([H])N1C(=O)C([H])([H])C([H])([H])[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])[H])[C@@]2([H])N([H])C([H])([H])C([H])([H])C2([H])[H])C1=O [H]ON([H])C(=O)C([H])([H])N1C(=O)C([H])([H])C([H])([H])[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])[H])C([H])([H])C2=C([H])C([H])=C(O[H])C([H])=C2[H])C1=O [H]ON([H])C(=O)C([H])([H])N1C(=O)C([H])([H])C([H])([H])[C@]([H])(N([H])C(=O)C2=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C(OC([H])([H])[H])=C2[H])C1=O [H]OC(=O)[C@@]([H])(N([H])C(=O)[C@@]1([H])N(C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])[C@@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])[H])C([H])([H])C2=C([H])N=C([H])N2[H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H] [H]OC(=O)[C@@]([H])(N([H])C(=O)[C@@]1([H])N(C(=O)[C@@]([H])(N([H])C(=O)[C@]2([H])N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@]([H])(N([H])[H])C([H])([H])C([H])([H])SSC([H])([H])C2([H])[H])C([H])([H])C2=C([H])C([H])=C(O[H])C([H])=C2[H])C([H])([H])C2=C([H])N=C([H])N2[H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H] [H]OC(=O)C([H])([H])C1=C(C([H])=C([H])C([H])=C1[H])C([H])([H])N([H])C(=O)[C@@]1([H])N([H])C(=O)C([H])([H])[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])[H])C([H])([H])C([H])([H])SSC1([H])[H])C([H])([H])C1=C([H])C([H])=C(O[H])C([H])=C1[H] [H]OC1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[C@]1([H])N([H])C(=O)[C@@]([H])(N([H])[H])C([H])([H])C([H])([H])SSC([H])([H])[C@]([H])(N([H])C(=O)C1([H])[H])C(=O)N([H])C([H])([H])C1=C([H])N=C([H])C([H])=C1[H] [H]OC(=O)C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1C([H])([H])N([H])C(=O)[C@@]1([H])N([H])C(=O)C([H])([H])[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])[H])C([H])([H])C([H])([H])SSC([H])([H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C(O[H])C([H])=C1[H] [H]N([H])[C@]1([H])C(=O)C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2C1([H])[H] [H]N([H])[C@@]1([H])C(=O)C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2C([H])([H])C1([H])[H] [H]OC(=O)C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1C([H])([H])N([H])C(=O)[C@@]1([H])N([H])C(=O)C([H])([H])[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])[H])C([H])([H])C([H])([H])\C([H])=C([H])\C([H])([H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C(O[H])C([H])=C1[H] [H]OC(=O)C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1C([H])([H])N([H])C(=O)[C@@]1([H])N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])[H])C([H])([H])C([H])([H])\C([H])=C([H])\C([H])([H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C(O[H])C([H])=C1[H] [H]OC(=O)C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1C([H])([H])N([H])C(=O)[C@]1([H])N([H])C(=O)C([H])([H])[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])[H])C([H])([H])C([H])([H])\C([H])=C([H])/C([H])([H])N1[H])C([H])([H])C1=C([H])C([H])=C(O[H])C([H])=C1[H] [H]N([H])[C@]1([H])C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])\C([H])=C([H])\C([H])([H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H] [H]OC(=O)C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1C([H])([H])N([H])C(=O)[C@@]1([H])N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C(O[H])C([H])=C1[H] [H]OC(=O)C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1C([H])([H])N([H])C(=O)[C@@]1([H])N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])\C([H])=C([H])\C1([H])[H])C([H])([H])C1=C([H])C([H])=C(O[H])C([H])=C1[H] [H]OC1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[C@]1([H])N([H])C(=O)[C@@]([H])(N([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@]([H])(N([H])C1=O)C(=O)N([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H] [H]O[C@@]([H])(C(=O)N([H])[C@@]([H])(C(=O)N([H])[C@@]([H])(C(=O)N([H])C([H])([H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])[C@]([H])(N([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H] [H]OC(=O)C([H])([H])[C@]([H])(N([H])C(=O)[C@]([H])(N([H])C(=O)[C@]([H])(O[H])[C@]([H])(N([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])C(=O)O[H] [H]SC([H])([H])[C@]([H])(N([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])[H] [H]S[C@@]([H])(C([H])([H])[H])[C@@]([H])(N([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H] [H]OC(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(S[H])[C@]([H])(N([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H] [H]OC(=O)[C@@]([H])(N([H])C(=O)[C@]([H])(C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[P@](=O)(O[H])[C@@]([H])([N+]([H])([H])[H])C([H])([H])C([H])([H])SC([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H] [H]OC(=O)C([H])([H])C([H])([H])[P@@](=O)(O[H])[C@]([H])(N([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H] [H]OC(=O)[C@@]([H])(C([H])([H])C1=C([H])C([H])=C(O[H])C([H])=C1[H])C([H])([H])[P@](=O)(O[H])[C@]([H])(N([H])[H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H] [H]OC(=O)[C@@]([H])(C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])[P@](=O)(O[H])[C@]([H])(N([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H] [H]OC(=O)[C@@]([H])(C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[P@](=O)(O[H])[C@]([H])(N([H])[H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H] [H]OC(=O)[C@@]([H])(C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])[P@@](=O)(O[H])[C@@]([H])(N([H])[H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H] [H]N(C(=O)[C@@]([H])(C([H])([H])SSC([H])([H])[C@@]([H])([N+]([H])([H])[H])C([H])([H])C([H])([H])SC([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])[C@@]([H])(C(=O)OC([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H] [H]O[P@@](=O)(C([H])([H])[C@@]([H])(C(=O)N([H])[C@]([H])(C([O-])=O)C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H])[C@@]([H])(C([H])([H])[H])[N+]([H])([H])[H] [H]O[P@@](=O)(C([H])([H])[C@@]([H])(C(=O)N([H])[C@]([H])(C([O-])=O)C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H])[C@@]([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])[N+]([H])([H])[H] [H]ON([H])C(=O)C([H])([H])[C@]([H])(C(=O)N([H])[C@]([H])(C([O-])=O)C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H] [H]ON([H])C(=O)[C@@]([H])(N([H])C(=O)N([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H] [H]OC(=O)[C@@]([H])(N([H])C(=O)[C@@]1([H])N(C(=O)[C@@]2([H])N(C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C3=C([H])C([H])=C(O[H])C([H])=C3[H])[C@@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])[H])C([H])([H])C3=C(N=C([H])N3[H])C2([H])[H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H] [H]OC(=O)[C@@]([H])(N([H])C(=O)[C@@]1([H])N(C(=O)[C@@]2([H])N(C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C3=C([H])C([H])=C(O[H])C([H])=C3[H])[C@@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])[H])C([H])([H])C3=C(C([H])=C([H])C([H])=C3[H])C2([H])[H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H] [H]OC(=O)[C@@]([H])(N([H])C(=O)C([H])([H])N1C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C2=C([H])C([H])=C(O[H])C([H])=C2[H])[C@@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])[H])C([H])([H])C2=C(N([H])C3=C2C([H])=C([H])C([H])=C3[H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H] [H]OC(=O)[C@@]([H])(N([H])C(=O)C([H])([H])N1C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C2=C([H])C([H])=C(O[H])C([H])=C2[H])[C@@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])[H])C([H])([H])C2=C(C([H])=C([H])C([H])=C2[H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H] [H]OC(=O)[C@@]([H])(N([H])C(=O)C([H])([H])N1C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(C([H])([H])N([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C2=C([H])C([H])=C(O[H])C([H])=C2[H])[C@@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])[H])C([H])([H])C2=C(C([H])=C([H])C([H])=C2[H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H] [H]OC(=O)[C@@]([H])(N([H])C(=O)C([H])([H])N1C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(C([H])([H])N([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C2=C([H])C([H])=C(O[H])C([H])=C2[H])[C@@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])[H])C([H])([H])C2=C(N([H])C3=C2C([H])=C([H])C([H])=C3[H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H] [H]OC(=O)[C@@]([H])(N([H])C(=O)C([H])([H])N1C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)C([H])([H])[C@]([H])(N([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C2=C([H])C([H])=C(O[H])C([H])=C2[H])[C@@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])[H])C([H])([H])C2=C(C([H])=C([H])C([H])=C2[H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H] [H]OC(=O)[C@@]([H])(N([H])C(=O)C([H])([H])N1C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)C([H])([H])[C@]([H])(N([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C2=C([H])C([H])=C(O[H])C([H])=C2[H])[C@@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])[H])C([H])([H])C2=C(N([H])C3=C2C([H])=C([H])C([H])=C3[H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H] [H]OC(=O)[C@@]([H])(N([H])C(=O)[C@@]1([H])N(C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C2=C([H])C([H])=C(O[H])C([H])=C2[H])[C@@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])[H])C([H])([H])C2=C([H])N=C([H])N2[H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H] [H]OC(=O)C([H])([H])[C@@]([H])(N([H])C(=O)[C@@]1([H])N(C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(C([H])([H])N([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C2=C([H])C([H])=C(O[H])C([H])=C2[H])[C@@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])[H])C([H])([H])C2=C([H])N=C([H])N2[H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H] [H]OC(=O)[C@@]([H])(N([H])C(=O)[C@@]1([H])N(C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(C([H])([H])N([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C2=C([H])C([H])=C(O[H])C([H])=C2[H])[C@@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])[H])C([H])([H])C2=C([H])N=C([H])N2[H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H] [H]OC(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])[H])C([H])([H])C([H])([H])C(=O)N([H])[H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=N[H])N([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])O[H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=N[H])N([H])[H] [H]OC(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])[H])C([H])([H])S[H])C([H])([H])C([H])([H])C(=O)N([H])[H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=N[H])N([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])O[H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=N[H])N([H])[H] [H]OC(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])[H])C([H])([H])C([H])([H])C(=O)N([H])[H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=N[H])N([H])[H])C([H])([H])C1=C([H])C([H])=C(F)C([H])=C1[H])C([H])([H])O[H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=N[H])N([H])[H] CC(C)C[C@H](NC(=O)NCC1=CC=CC=C1Br)C(=O)NO CC(C)C[C@H](NC(=O)NCC1=CC=CC=C1Cl)C(=O)NO COC1=C(NC(=O)N[C@@H](CC(C)C)C(=O)NO)C=CC=C1 CC(C)C[C@H](NC(=O)NC1=C(C)C=CC=C1)C(=O)NO CC(C)C[C@H](NC(=O)NC1=C(Br)C=CC=C1)C(=O)NO CC(C)C[C@H](NC(=O)NC1=C(Cl)C=CC=C1)C(=O)NO NC1CCC2=C(Br)C=CC(C3=CC=CC=C3)=C2CC1=O [H]N([H])[C@]1([H])C(=O)C([H])([H])C2=C(C([H])=C([H])C([H])=C2C([H])([H])C1([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]