[H]C1=C(N2C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])C([H])([H])N3C(=O)C(S[C@]3([H])C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C2([H])[H])C2=C(S1)C([H])=C(F)C([H])=C2[H]
[H]OC1=C([H])C([H])=C2C(=C1O[H])C([H])([H])[C@@]([H])(O[C@@]2([H])C([H])([H])N([H])[H])[C@]12C([H])([H])[C@@]3([H])C([H])([H])[C@]([H])(C([H])([H])[C@]([H])(C3([H])[H])C1([H])[H])C2([H])[H]
[H]OC1=C([H])C([H])=C2C(=C1O[H])C([H])([H])[C@@]([H])(O[C@@]2([H])C([H])([H])N([H])[H])C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]OC1=C([H])C([H])=C2C(=C1O[H])C([H])([H])[C@@]([H])(O[C@@]2([H])C([H])([H])N([H])[H])C([H])([H])OC1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC1=C(O[H])C([H])=C2C(=C1[H])C([H])([H])C([H])([H])N(C([H])([H])C([H])=C([H])[H])C([H])([H])[C@]2([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC1=C([H])C2=C(C([H])=C1O[H])[C@@]([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])N([H])C([H])([H])C2([H])[H]
[H]OC1=C(O[H])C(Br)=C2C(=C1[H])[C@]([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])N(C([H])([H])C([H])=C([H])[H])C([H])([H])C2([H])[H]
[H]OC1=C([H])C([H])=C2C(=C1O[H])C([H])([H])[C@@]([H])(O[C@@]2([H])C([H])([H])N([H])[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]OC1=C([H])C([H])=C2C(=C1O[H])C([H])([H])[C@@]([H])(O[C@@]2([H])C([H])([H])N([H])C([H])([H])C#C[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]OC1=C([H])C([H])=C2C(=C1O[H])C([H])([H])[C@@]([H])(O[C@@]2([H])C([H])([H])N([H])C1([H])C([H])([H])C1([H])[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]OC1=C([H])C([H])=C2C(=C1O[H])C([H])([H])[C@]([H])(O[C@@]2([H])C([H])([H])N([H])[H])C1=C([H])C([H])=C([H])C(OC([H])([H])[H])=C1[H]
[H]OC1=C([H])C([H])=C2C(=C1O[H])C([H])([H])[C@@]([H])(O[C@@]2([H])C([H])([H])N([H])[H])C([H])([H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]N(C(=O)[C@]12C([H])([H])[C@@]3([H])C([H])([H])[C@]([H])(C([H])([H])[C@]([H])(C3([H])[H])C1([H])[H])C2([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C(OC([H])([H])[H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]OC1=C([H])C([H])=C2C(=C1O[H])C([H])([H])[C@@]([H])(O[C@@]2([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C([H])=C([H])[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]OC1(C2=C([H])C([H])=C(Cl)C([H])=C2[H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])C(=O)C2=C([H])C([H])=C(F)C([H])=C2[H])C([H])([H])C1([H])[H]
[H]C1=C([H])C2=C(C([H])=C1[H])C([H])([H])[C@]([H])(N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H])C1=C([H])C(Cl)=C([H])C([H])=C1S2
[H]OC1=C([H])C([H])=C2C(=C1O[H])C([H])([H])[C@]1(O[C@@]2([H])C([H])([H])N([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]OC1=C([H])C([H])=C2C(=C1O[H])C([H])([H])[C@]([H])(O[C@@]2([H])C([H])([H])N([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC1=C([H])C([H])=C2C(=C1O[H])C([H])([H])[C@]([H])(O[C@@]2([H])C([H])([H])N([H])C([H])([H])C([H])=C([H])[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]OC1=C([H])C([H])=C2C(=C1O[H])C([H])([H])[C@@]([H])(O[C@@]2([H])C([H])([H])N([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC1=C([H])C([H])=C2C(=C1O[H])C([H])([H])[C@]([H])(O[C@@]2([H])C([H])([H])N([H])[H])C1=C([H])C([H])=C(Br)C([H])=C1[H]
[H]OC1=C([H])C([H])=C2C(=C1O[H])C([H])([H])[C@@]([H])(O[C@@]2([H])C([H])([H])N([H])[H])C([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC1=C([H])C([H])=C2C(=C1O[H])C([H])([H])[C@@]([H])(O[C@@]2([H])C([H])([H])N([H])[H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC1=C([H])C([H])=C2C(=C1O[H])C([H])([H])[C@]([H])(O[C@@]2([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C#C[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]OC1=C([H])C([H])=C2C(=C1O[H])C([H])([H])[C@@]([H])(O[C@@]2([H])C([H])([H])N([H])[H])C([H])([H])C#C[H]
[H]OC1=C([H])C([H])=C2C(=C1O[H])C([H])([H])[C@]([H])(O[C@@]2([H])C([H])([H])N([H])[H])C1=C([H])C([H])=C(I)C([H])=C1[H]
[H]OC1=C([H])C([H])=C2C(=C1O[H])C([H])([H])[C@@]([H])(O[C@@]2([H])C([H])([H])N([H])C([H])([H])C([H])([H])C([H])([H])O[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]OC1=C([H])C([H])=C2C(=C1O[H])C([H])([H])[C@@]([H])(O[C@@]2([H])C([H])([H])N([H])[H])C([H])([H])OC([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])N1C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])N1C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])C2=C([H])C([H])=C3C([H])=C([H])C([H])=C([H])C3=C2[H])C([H])([H])C1([H])[H]
[H]OC1=C([H])C([H])=C2C(=C1O[H])C([H])([H])[C@@]([H])(O[C@@]2([H])C([H])([H])N([H])C([H])([H])[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]OC1=C([H])C([H])=C2C(=C1O[H])C([H])([H])C([H])([H])O[C@@]2([H])C([H])([H])N([H])[H]
[H]OC1=C([H])C2=C3C(=C1[H])C([H])([H])C([H])([H])N(C([H])([H])[H])[C@@]3([H])C([H])([H])C1=C2C(O[H])=C(O[H])C([H])=C1[H]
[H]OC1=C(O[H])C2=C(C([H])=C1[H])C([H])([H])[C@@]1([H])N(C([H])([H])[H])C([H])([H])C([H])([H])C3=C([H])C(Cl)=C([H])C2=C13
[H]OC1=C([H])C([H])=C2C(=C1O[H])C1=C3C(=C([H])C([H])=C1[H])C([H])([H])C([H])([H])N(C([H])([H])[H])[C@]3([H])C2([H])[H]
[H]OC1=C([H])C2=C3C(=C1[H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])[H])[C@]3([H])C([H])([H])C1=C2C(O[H])=C(O[H])C([H])=C1[H]
[H]OC1=C(O[H])C2=C(C([H])=C1[H])C([H])([H])[C@@]1([H])N(C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C3=C([H])C(OC([H])([H])[H])=C([H])C2=C13
[H]N([H])C1=C(Cl)C([H])=C(C(=O)N([H])[C@]2([H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])OC3=C([H])C([H])=C(F)C([H])=C3[H])C([H])([H])[C@]2([H])OC([H])([H])[H])C(OC([H])([H])[H])=C1[H]
[H]OC1=C(O[H])C2=C(C([H])=C1[H])C([H])([H])[C@@]1([H])N(C([H])([H])[H])C([H])([H])C([H])([H])C3=C1C2=C([H])C(Br)=C3[H]
[H]N1C2=C(N=C(N3C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C3([H])[H])C3=C1C([H])=C([H])C([H])=C3[H])C([H])=C([H])C([H])=C2[H]
[H]C1=C([H])C2=C(C([H])=C1[H])C(=C(C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C(Cl)C([H])=C1C([H])=C2N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H]
[H]C([H])=C1C2=C([H])C([H])=C([H])C([H])=C2C([H])=C(N2C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C2([H])[H])C2=C1C([H])=C([H])C([H])=C2[H]
[H]N1C2=C(N=C(N3C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C3([H])[H])C3=C1C([H])=C([H])C(Cl)=C3[H])C([H])=C([H])C([H])=C2[H]
[H]C([H])=C1C2=C([H])C([H])=C(Cl)C([H])=C2C([H])=C(N2C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C2([H])[H])C2=C1C([H])=C([H])C([H])=C2[H]
[H]OC1=C(O[H])C([H])=C2C(=C1[H])C([H])([H])[C@]([H])(N(C([H])([H])[H])C([H])([H])[H])C([H])([H])[C@@]2([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])[C@@]1([H])C2=C([H])C([H])=C([H])C([H])=C2C([H])([H])[C@@](N(C([H])([H])[H])C([H])([H])[H])(C([H])([H])[H])C1([H])[H]
[H]OC1=C(Cl)C([H])=C2C(=C1[H])[C@]([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[C@@]([H])(N(C([H])([H])[H])C([H])([H])[H])C2([H])[H]
[H]OC1=C(Cl)C([H])=C2C(=C1[H])[C@]([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[C@@]([H])(N([H])C([H])([H])[H])C2([H])[H]
[H]OC1=C([H])C([H])=C2C(=C1O[H])C1=C([H])C([H])=C([H])C3=C1[C@]([H])(N(C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C3([H])[H])C2([H])[H]
[H]OC1=C(O[H])C2=C(C([H])=C1[H])C([H])([H])[C@@]1([H])N(C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C3=C([H])C(Br)=C([H])C2=C13
[H]OC1=C(O[H])C2=C(C([H])=C1[H])C([H])([H])[C@@]1([H])N(C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C3=C([H])C(F)=C([H])C2=C13
[H]C1=C([H])C2=C(C3=C1OC([H])([H])O3)C1=C3C(=C([H])C(F)=C1[H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])[H])[C@]3([H])C2([H])[H]
[H]C1=C([H])C2=C(C([H])=C1[H])C(=C(C([H])([H])[H])C([H])([H])[H])C1=C(C([H])=C(Cl)C([H])=C1[H])C(=C2[H])N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H]
[H]C1=C([H])C2=C(C([H])=C1[H])C(=C(C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1C([H])=C2N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N1C2=C([H])C([H])=C([H])C([H])=C2C(=NC2=C1C([H])=C([H])C(Cl)=C2[H])N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H]
[H]C([H])=C1C2=C(C([H])=C([H])C([H])=C2[H])C([H])=C(N2C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C2([H])[H])C2=C1C([H])=C([H])C(Cl)=C2[H]
[H]OC1=C(O[H])C(Cl)=C2C(=C1[H])[C@@]([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])N(C([H])([H])C([H])=C([H])[H])C([H])([H])C2([H])[H]
[H]N1C([H])([H])C([H])([H])N(C2=C([H])C([H])=C([H])C(=C2[H])C(F)(F)F)C([H])([H])C1([H])[H]
[H]N1C([H])([H])C([H])([H])N(C2=C([H])C([H])=C([H])C([H])=C2C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]OC1=C([H])C([H])=C([H])C([H])=C1N1C([H])([H])C([H])([H])N([H])C([H])([H])C1([H])[H]
[H]N1C([H])([H])C([H])([H])N(C2=C([H])C([H])=C([H])C([H])=C2OC([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N(C(=O)N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H])[C@]1([H])C([H])([H])N(C([H])([H])[H])[C@]2([H])C([H])([H])C3=C([H])N([H])C4=C3C(=C([H])C([H])=C4[H])[C@@]2([H])C1([H])[H]
[H]C1=C([H])C([H])=C2N(C3=C(SC2=C1[H])C([H])=C([H])C(SC([H])([H])[H])=C3[H])C([H])([H])C([H])([H])[C@]1([H])N(C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N1C([H])([H])C([H])([H])N(C2=C([H])C([H])=C([H])C([H])=C2F)C([H])([H])C1([H])[H]
[H]OC1=C([H])C([H])=C(Cl)C2=C1C1=C3C(=C([H])C([H])=C1[H])C([H])([H])C([H])([H])N(C([H])([H])[H])[C@]3([H])C2([H])[H]
[H]OC1=C([H])C([H])=C([H])C2=C1C1=C3C(=C([H])C([H])=C1[H])C([H])([H])C([H])([H])N(C([H])([H])[H])[C@@]3([H])C2([H])[H]
[H]C1=C([H])C(OC([H])([H])[H])=C2C3=C4C(=C([H])C([H])=C3[H])C([H])([H])C([H])([H])N(C([H])([H])[H])[C@]4([H])C([H])([H])C2=C1[H]
[H]OC1=C([H])C([H])=C(Br)C2=C1C1=C3C(=C([H])C([H])=C1[H])C([H])([H])C([H])([H])N(C([H])([H])[H])[C@@]3([H])C2([H])[H]
[H]OC1=C(Br)C([H])=C([H])C2=C1C1=C3C(=C([H])C([H])=C1[H])C([H])([H])C([H])([H])N(C([H])([H])[H])[C@@]3([H])C2([H])[H]
[H]OC1=C([H])C(Br)=C([H])C2=C1C1=C3C(=C([H])C([H])=C1[H])C([H])([H])C([H])([H])N(C([H])([H])[H])[C@@]3([H])C2([H])[H]
[H]OC1=C(Cl)C([H])=C([H])C2=C1C1=C3C(=C([H])C([H])=C1[H])C([H])([H])C([H])([H])N(C([H])([H])[H])[C@]3([H])C2([H])[H]
[H]OC1=C(Br)C([H])=C(Br)C2=C1C1=C3C(=C([H])C([H])=C1[H])C([H])([H])C([H])([H])N(C([H])([H])[H])[C@]3([H])C2([H])[H]
[H]OC1=C(Cl)C([H])=C2C(=C1[H])[C@@]([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])N(C([H])([H])[H])C([H])([H])C2([H])[H]
[H]OC1=C(OC([H])([H])[H])C([H])=C([H])C2=C1C1=C3OC([H])([H])OC3=C([H])C3=C1[C@@]([H])(N(C([H])([H])[H])C([H])([H])C3([H])[H])C2([H])[H]
[H]N1C([H])([H])C([H])([H])N(C2=C([H])C([H])=C([H])C(F)=C2[H])C([H])([H])C1([H])[H]
[H]N1C([H])([H])C([H])([H])N(C2=C([H])C([H])=C([H])C([H])=C2Cl)C([H])([H])C1([H])[H]
[H]N1C([H])([H])C([H])([H])N(C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N1C([H])([H])C([H])([H])N(C2=C([H])C([H])=C([H])C(Cl)=C2[H])C([H])([H])C1([H])[H]
[H]N1C([H])([H])C([H])([H])N(C2=C([H])C([H])=C([H])C([H])=C2OC([H])([H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N1C([H])([H])C([H])([H])N(C2=C([H])C([H])=C([H])C([H])=C2C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]OC1=C(O[H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])N([H])[H]
[H]\C(=C1/C2=C(C([H])=C([H])C([H])=C2[H])C([H])=C(N2C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C2([H])[H])C2=C1C([H])=C([H])C(Cl)=C2[H])C([H])([H])[H]
[H]C1=C([H])C2=C(C([H])=C1[H])[C@]([H])(C1=C(C([H])=C(Cl)C([H])=C1[H])C(=C2[H])N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H])C([H])([H])[H]
[H]N1C(=O)N(C(=O)C2=C([H])C([H])=C([H])C([H])=C12)C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])(C(=O)C2=C([H])C([H])=C(F)C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N1C(=O)C2(N(C3=C([H])C([H])=C([H])C([H])=C3[H])C1([H])[H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])C(=O)C1=C([H])C([H])=C(F)C([H])=C1[H])C([H])([H])C2([H])[H]
[H]OC1=C(Cl)C([H])=C2C(=C1[H])[C@@]([H])(C1=C([H])C([H])=C(I)C([H])=C1[H])C([H])([H])N(C([H])([H])[H])C([H])([H])C2([H])[H]
[H]N1C([H])([H])C([H])([H])N(C2=C([H])C([H])=C([H])C([H])=C2C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N1C([H])([H])C([H])([H])N(C2=C([H])C([H])=C([H])C([H])=C2C([H])([H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]OC1=C([H])C([H])=C2C(=C1[H])[C@@]([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])N(C([H])([H])[H])C([H])([H])C2([H])[H]
[H]N1C([H])([H])C([H])([H])N(C2=C([H])C([H])=C([H])C([H])=C2OC([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N1C([H])([H])C([H])([H])N(C2=C([H])C([H])=C([H])C([H])=C2C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N1C([H])([H])C([H])([H])N(C2=C([H])C([H])=C([H])C([H])=C2C#N)C([H])([H])C1([H])[H]
[H]OC1=C(Br)C([H])=C2C(=C1[H])[C@@]([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])N(C([H])([H])[H])C([H])([H])C2([H])[H]
[H]OC1=C(I)C([H])=C2C(=C1[H])[C@@]([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])N(C([H])([H])[H])C([H])([H])C2([H])[H]
[H]N1C([H])([H])C([H])([H])N(C2=C([H])C([H])=C([H])C(=C2[H])[N+]([O-])=O)C([H])([H])C1([H])[H]
[H]N1C([H])([H])C([H])([H])N(C2=NC(Cl)=C([H])N=C2[H])C([H])([H])C1([H])[H]
[H]N1C([H])([H])C([H])([H])N(C2=C([H])C([H])=C([H])C([H])=C2OC([H])([H])[H])C([H])([H])C1([H])[H]
[H]C1=C([H])C2=C(C([H])=C1[H])C(=NS2)N1C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])ON2C(=O)C([H])([H])C3(C([H])([H])C([H])([H])C([H])([H])C3([H])[H])C([H])([H])C2=O)C([H])([H])C1([H])[H]
[H]OC1=C(C([H])=C2C(=C1[H])[C@@]1([H])C3=C(C([H])=C([H])C([H])=C3[H])C([H])([H])C([H])([H])[C@]1([H])N(C([H])([H])[H])C([H])([H])C2([H])[H])C([H])([H])[H]
[H]OC1=C(Cl)C([H])=C2C(=C1[H])[C@@]1([H])C3=C(C([H])=C([H])C([H])=C3[H])C([H])([H])C([H])([H])[C@@]1([H])N(C([H])([H])[H])C([H])([H])C2([H])[H]
[H]OC1=C(O[H])C([H])=C2C(=C1[H])C([H])([H])C([H])([H])N(C([H])([H])[H])[C@@]1([H])C([H])([H])C([H])([H])C3=C(C([H])=C([H])C([H])=C3[H])[C@@]21[H]
[H]OC1=NC2=C(S1)C(=C([H])C([H])=C2O[H])C([H])([H])C([H])([H])N([H])[H]
[H]OC1=C2N([H])C(=O)C([H])([H])C2=C(C([H])=C1[H])C([H])([H])C([H])([H])N([H])[H]
[H]OC1=C([H])C([H])=C(C([H])=C1[H])[C@@]1([H])C2=C(C(Cl)=C(O[H])C(O[H])=C2[H])C([H])([H])C([H])([H])N([H])C1([H])[H]
[H]OC1=C([H])C([H])=C2C(=C1[H])[C@@]1(C([H])([H])[H])C([H])([H])C([H])([H])N(C([H])([H])C([H])=C(C([H])([H])[H])C([H])([H])[H])[C@@]([H])(C2([H])[H])[C@@]1([H])C([H])([H])[H]
[H]C1=C2C(=C([H])C(Cl)=C1[H])[C@@]([H])(N1C([H])([H])C([H])([H])N(C([H])([H])[H])C3(C1([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C3([H])[H])C([H])([H])[C@@]2([H])C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]C1=C2C(=C([H])C(Cl)=C1[H])[C@@]([H])(C1=C([H])C([H])=C(F)C([H])=C1[H])C([H])([H])[C@@]2([H])N1C([H])([H])C([H])([H])N(C([H])([H])[H])C(C([H])([H])[H])(C([H])([H])[H])C1([H])[H]
[H]OC1=C(OC([H])([H])[H])C([H])=C2C(=C1[H])[C@]1([H])C3=C(C([H])=C([H])C([H])=C3[H])C([H])([H])C([H])([H])[C@]1([H])N(C([H])([H])[H])C([H])([H])C2([H])[H]
[H]OC1=C([H])C([H])=C2C(=C1[H])[C@@]1([H])C3=C(C([H])=C([H])C([H])=C3[H])C([H])([H])C([H])([H])[C@]1([H])N(C([H])([H])[H])C([H])([H])C2([H])[H]
[H]OC1=C([H])C2=C3C(=C1O[H])C([H])([H])C([H])([H])[C@]3([H])C([H])([H])N([H])C([H])([H])[C@]2([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC1=C(O[H])C2=C(C([H])=C1[H])C([H])([H])[C@@]1([H])N(C([H])([H])C([H])=C([H])[H])C([H])([H])C([H])([H])C3=C([H])C([H])=C([H])C2=C13
[H]OC1=C([H])C([H])=C([H])C2=C1C1=C3C(=C([H])C([H])=C1[H])C([H])([H])C([H])([H])N(C([H])([H])C([H])=C([H])[H])[C@]3([H])C2([H])[H]
[H]OC1=C([H])C([H])=C([H])C2=C1C1=C3C(=C([H])C([H])=C1[H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])[H])[C@]3([H])C2([H])[H]
[H]OC1=C2C(=C([H])C([H])=C1Br)[C@@]([H])(O[C@]([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C2([H])[H])C([H])([H])N([H])[H]
[H]OC1=C2C(=C([H])C([H])=C1C([H])([H])[H])[C@@]([H])(O[C@@]([H])(C2([H])[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])N([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]OC1=C2C(=C([H])C([H])=C1OC([H])([H])[H])[C@@]([H])(O[C@]([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C2([H])[H])C([H])([H])N([H])[H]
[H]OC1=C2C(=C([H])C([H])=C1C([H])([H])[H])[C@@]([H])(O[C@@]([H])(C2([H])[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])N([H])C([H])([H])[H]
[H]OC1=C2C(=C([H])C([H])=C1C([H])([H])[H])[C@@]([H])(O[C@@]([H])(C2([H])[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H]
[H]OC1=C2C(=C([H])C([H])=C1[H])[C@@]([H])(O[C@]([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C2([H])[H])C([H])([H])N([H])[H]
[H]OC1=C2C(=C([H])C([H])=C1C([H])([H])[H])[C@@]([H])(O[C@@]([H])(C2([H])[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])N([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C1(C(=O)OC([H])([H])C([H])([H])N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]OC1=C(F)C([H])=C([H])C(=C1[H])C([H])([H])C([H])([H])N([H])[H]
[H]OC1=C(F)C([H])=C([H])C(=C1[H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C1=C([H])C2=C(C([H])=C1[H])C([H])([H])[C@]1([H])N(C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C3=C1C2=C([H])C([H])=C3[H]
[H]N1C([H])([H])C([H])([H])N(C([H])([H])C1(C([H])([H])[H])C([H])([H])[H])[C@]1([H])C2=C([H])C(=C([H])C([H])=C2[C@]([H])(C2=C([H])C([H])=C(F)C([H])=C2[H])C1([H])[H])C(F)(F)F
[H]N1C([H])([H])C([H])([H])N(C([H])([H])C1(C([H])([H])[H])C([H])([H])[H])[C@]1([H])C2=C([H])C(=C([H])C([H])=C2[C@]([H])(C2=C([H])C([H])=C(F)C([H])=C2[H])C1([H])[H])C([H])([H])[H]
[H]N1C([H])([H])C([H])([H])N(C([H])([H])C1(C([H])([H])[H])C([H])([H])[H])[C@]1([H])C2=C([H])C(Cl)=C([H])C([H])=C2[C@]([H])(C2=C([H])SC([H])=C2[H])C1([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])[C@@]1([H])C2=C([H])C([H])=C(Cl)C([H])=C2[C@@]([H])(N2C([H])([H])C([H])([H])N(C([H])([H])[H])C(C([H])([H])[H])(C([H])([H])[H])C2([H])[H])C1([H])[H]
[H]C1=C([H])C(F)=C2C(=C1[H])[C@@]([H])(C1=C([H])C([H])=C(F)C([H])=C1[H])C([H])([H])[C@@]2([H])N1C([H])([H])C([H])([H])N(C([H])([H])[H])C(C([H])([H])[H])(C([H])([H])[H])C1([H])[H]
[H]C1=C2C(=C([H])C(F)=C1[H])[C@@]([H])(N1C([H])([H])C([H])([H])N(C([H])([H])[H])C(C([H])([H])[H])(C([H])([H])[H])C1([H])[H])C([H])([H])[C@@]2([H])C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]C1=C([H])C([H])=C2C(=C1[H])[C@]([H])(N1C([H])([H])C([H])([H])N(C([H])([H])[H])C(C([H])([H])[H])(C([H])([H])[H])C1([H])[H])C([H])([H])[C@]2([H])C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]C1=C2C(=C([H])C(F)=C1[H])[C@@]([H])(N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H])C([H])([H])[C@@]2([H])C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])[C@@]1([H])C2=C([H])C([H])=C(Cl)C([H])=C2[C@@]([H])(N2C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C2([H])[H])C1([H])[H]
[H]C1=C2C(=C([H])C(Cl)=C1[H])[C@@]([H])(N1C([H])([H])C([H])([H])N(C([H])(C([H])([H])[H])C([H])([H])[H])C(C([H])([H])[H])(C([H])([H])[H])C1([H])[H])C([H])([H])[C@@]2([H])C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])[C@]1([H])C2=C([H])C([H])=C([H])C([H])=C2[C@]([H])(N2C([H])([H])C([H])([H])N(C([H])([H])[H])C(C([H])([H])[H])(C([H])([H])[H])C2([H])[H])C1([H])[H]
[H]C1=C2C(=C([H])C(Cl)=C1[H])[C@@]([H])(N1C([H])([H])C([H])([H])N(C([H])([H])[H])C3(C([H])([H])C([H])([H])C([H])([H])C3([H])[H])C1([H])[H])C([H])([H])[C@@]2([H])C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]C1=C([H])C(=C([H])S1)[C@@]1([H])C2=C([H])C([H])=C(Cl)C([H])=C2[C@@]([H])(N2C([H])([H])C([H])([H])N(C([H])([H])[H])C(C([H])([H])[H])(C([H])([H])[H])C2([H])[H])C1([H])[H]
[H]C1=C2C(=C([H])C(=C1[H])C(F)(F)F)[C@@]([H])(N1C([H])([H])C([H])([H])N(C([H])([H])[H])C(C([H])([H])[H])(C([H])([H])[H])C1([H])[H])C([H])([H])[C@@]2([H])C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]OC([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])[C@@]1([H])C2=C(C([H])=C(Cl)C([H])=C2[H])[C@@]([H])(C2=C([H])C([H])=C(F)C([H])=C2[H])C1([H])[H]
[H]C1=C([H])C([H])=C(C(F)=C1[H])[C@@]1([H])C2=C([H])C([H])=C(Cl)C([H])=C2[C@@]([H])(N2C([H])([H])C([H])([H])N(C([H])([H])[H])C(C([H])([H])[H])(C([H])([H])[H])C2([H])[H])C1([H])[H]
[H]C1=C2C(=C([H])C(=C1[H])C([H])([H])[H])[C@@]([H])(N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H])C([H])([H])[C@@]2([H])C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]C1=C([H])C(F)=C([H])C(=C1[H])[C@@]1([H])C2=C([H])C([H])=C(Cl)C([H])=C2[C@@]([H])(N2C([H])([H])C([H])([H])N(C([H])([H])[H])C(C([H])([H])[H])(C([H])([H])[H])C2([H])[H])C1([H])[H]
[H]C1=C2C(=C([H])C(=C1[H])C([H])([H])[H])[C@@]([H])(N1C([H])([H])C([H])([H])N(C([H])([H])[H])C(C([H])([H])[H])(C([H])([H])[H])C1([H])[H])C([H])([H])[C@@]2([H])C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]OC([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])[C@]1([H])C2=C([H])C(=C([H])C([H])=C2[C@]([H])(C2=C([H])C([H])=C(F)C([H])=C2[H])C1([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]OC([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])[C@]1([H])C2=C(C([H])=C([H])C(=C2[H])C(F)(F)F)[C@]([H])(C2=C([H])C([H])=C(F)C([H])=C2[H])C1([H])[H]
[H]C1=C([H])C(Cl)=C2C(=C1[H])[C@@]([H])(C1=C([H])C([H])=C(F)C([H])=C1[H])C([H])([H])[C@@]2([H])N1C([H])([H])C([H])([H])N(C([H])([H])[H])C(C([H])([H])[H])(C([H])([H])[H])C1([H])[H]
[H]OC([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])[C@]1([H])C2=C([H])C(SC([H])([H])[H])=C([H])C([H])=C2[C@]([H])(C2=C([H])C([H])=C(F)C([H])=C2[H])C1([H])[H]
[H]OC([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])[C@]1([H])C2=C([H])C(=C([H])C([H])=C2[C@]([H])(C2=C([H])C([H])=C(F)C([H])=C2[H])C1([H])[H])S(=O)(=O)C([H])([H])[H]
[H]N1C([H])([H])C([H])([H])N(C([H])([H])C1(C([H])([H])[H])C([H])([H])[H])[C@]1([H])C2=C([H])C(Cl)=C([H])C([H])=C2[C@]([H])(C2=C([H])C([H])=C(F)C([H])=C2[H])C1([H])[H]
[H]OC([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C([H])([H])C1(C([H])([H])[H])C([H])([H])[H])[C@]1([H])C2=C([H])C(Cl)=C([H])C([H])=C2[C@]([H])(C2=C([H])C([H])=C(F)C([H])=C2[H])C1([H])[H]
[H]OC([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C([H])([H])C11C([H])([H])C([H])([H])C([H])([H])C1([H])[H])[C@]1([H])C2=C([H])C(Cl)=C([H])C([H])=C2[C@]([H])(C2=C([H])C([H])=C(F)C([H])=C2[H])C1([H])[H]
[H]OC1=C([H])C2=C(C([H])=C1Cl)C([H])([H])C([H])([H])N(C([H])([H])[H])[C@]([H])(C([H])([H])[H])[C@@]2(C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H]
[H]OC([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])[C@]1([H])C2=C(C([H])=C([H])C(Cl)=C2[H])[C@]([H])(C2=C([H])C([H])=C(F)C([H])=C2[H])C1([H])[H]
[H]C1=C2C(=C([H])C(=C1[H])C(F)(F)F)[C@@]([H])(N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H])C([H])([H])[C@@]2([H])C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]OC([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])[C@]1([H])C2=C(C(Cl)=C([H])C([H])=C2[H])[C@]([H])(C2=C([H])C([H])=C(F)C([H])=C2[H])C1([H])[H]
[H]C1=C2C(=C([H])C(Cl)=C1[H])[C@@]([H])(N1C([H])([H])C([H])([H])N(C([H])([H])[H])C(C([H])([H])C([H])([H])[H])(C([H])([H])C([H])([H])[H])C1([H])[H])C([H])([H])[C@@]2([H])C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]C1=C([H])C(Cl)=C2C(=C1[H])[C@]([H])(N1C([H])([H])C([H])([H])N(C([H])([H])[H])C(C([H])([H])[H])(C([H])([H])[H])C1([H])[H])C([H])([H])[C@]2([H])C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]OC([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])[C@]1([H])C2=C([H])C(OC([H])([H])[H])=C([H])C([H])=C2[C@]([H])(C2=C([H])C([H])=C(F)C([H])=C2[H])C1([H])[H]
[H]C1=C2C(=C([H])C(Cl)=C1[H])[C@@]([H])(N1C([H])([H])C([H])([H])N(C([H])([H])[H])C3(C([H])([H])C([H])([H])C3([H])[H])C1([H])[H])C([H])([H])[C@@]2([H])C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]OC([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C([H])([H])C1(C([H])([H])[H])C([H])([H])[H])[C@]1([H])C2=C([H])C(Cl)=C([H])C([H])=C2[C@]([H])(C2=C([H])C([H])=C(F)C([H])=C2[H])C1([H])[H]
[H]OC([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])[C@@]1([H])C2=C(C([H])=C([H])C([H])=C2Cl)[C@@]([H])(C2=C([H])C([H])=C(F)C([H])=C2[H])C1([H])[H]
[H]C1=C2C(=C([H])C(Br)=C1[H])[C@@]([H])(N1C([H])([H])C([H])([H])N(C([H])([H])[H])C(C([H])([H])[H])(C([H])([H])[H])C1([H])[H])C([H])([H])[C@@]2([H])C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]OC([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])[C@]1([H])C2=C([H])C(F)=C([H])C([H])=C2[C@]([H])(C2=C([H])C([H])=C(F)C([H])=C2[H])C1([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])[C@]1([H])C2=C([H])C([H])=C([H])C([H])=C2[C@]([H])(N2C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C2([H])[H])C1([H])[H]
[H]OC([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])[C@@]1([H])C2=C([H])C([H])=C([H])C([H])=C2[C@@]([H])(C2=C([H])C([H])=C([H])C([H])=C2[H])C1([H])[H]
[H]OC([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])[C@]1([H])C2=C([H])C(=C([H])C([H])=C2[C@]([H])(C2=C([H])C([H])=C(F)C([H])=C2[H])C1([H])[H])C([H])([H])[H]
[H]OC1=C(O[H])C([H])=C2C(=C1[H])C([H])([H])C([H])([H])[C@@]1([H])N(C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C3=C(C([H])=C([H])C([H])=C3[H])[C@]21[H]
[H]OC1=C(O[H])C([H])=C2C(=C1[H])C([H])([H])C([H])([H])[C@@]([H])(N([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C2([H])[H]
[H]OC1=C(O[H])C([H])=C2C(=C1[H])C([H])([H])C([H])([H])[C@@]1([H])N([H])C([H])([H])C3=C(C([H])=C([H])C([H])=C3[H])[C@]21[H]
[H]OC1=C(O[H])C([H])=C2C(=C1[H])C([H])([H])C([H])([H])[C@@]1([H])N([H])C([H])([H])C([H])([H])C([H])([H])[C@]21[H]
[H]OC1=C(O[H])C([H])=C(C([H])=C1[H])[C@@]1([H])C2=C(SC([H])=C2[H])C([H])([H])N([H])C1([H])[H]
[H]OC1=C(O[H])C([H])=C2C(=C1[H])C([H])([H])C([H])([H])[C@@]1([H])N(C([H])([H])[H])C([H])([H])C3=C(C([H])=C([H])C([H])=C3[H])[C@]21[H]
[H]N1C([H])=C(C2=C([H])C(=C([H])C([H])=C12)C([H])([H])[C@]1([H])N([H])C(=O)OC1([H])[H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])C2=C(N=C(N3C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C3([H])[H])C3=C(S2)C([H])=C([H])C(Cl)=C3[H])C([H])=C1[H]
[H]C1=C([H])C2=C(C([H])=C1[H])C(=NC1=C(S2)C([H])=C([H])C(Cl)=C1[H])N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H]
[H]C1=C([H])C2=C(C([H])=C1[H])C([H])([H])C1=C(N=C2N2C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C2([H])[H])C([H])=C(F)C([H])=C1[H]
[H]C1=C([H])C2=C(C([H])=C1[H])N(C1=C([H])C(Cl)=C([H])C([H])=C1S2)C([H])([H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H]
[H]OC1=C([H])C2=C(C([H])=C1Br)C([H])([H])C([H])([H])[C@@]1([H])N(C([H])([H])[H])C([H])([H])C3=C(C([H])=C([H])C([H])=C3[H])[C@]21[H]
[H]OC1=C([H])C([H])=C2C(=C1[H])[C@]1([H])C3=C(C([H])=C([H])C([H])=C3[H])C([H])([H])N([H])[C@]1([H])C([H])([H])C2([H])[H]
[H]OC1=C2C(=C([H])C([H])=C1[H])[C@]1([H])C3=C(C([H])=C([H])C([H])=C3[H])C([H])([H])N([H])[C@]1([H])C([H])([H])C2([H])[H]
[H]OC1=C([H])C([H])=C2C(=C1[H])[C@@]1([H])C3=C(C([H])=C([H])C([H])=C3[H])C([H])([H])N(C([H])([H])[H])[C@]1([H])C([H])([H])C2([H])[H]
[H]OC1=C([H])C([H])=C2C(=C1[H])[C@@]1([H])C3=C(C([H])=C([H])C([H])=C3[H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])[H])[C@]1([H])C([H])([H])C2([H])[H]
[H]OC1=C([H])C([H])=C2C(=C1O[H])C([H])([H])C([H])([H])[C@@]1([H])N(C([H])([H])[H])C([H])([H])C3=C(C([H])=C([H])C([H])=C3[H])[C@]21[H]
[H]OC1=C(Cl)C([H])=C2C(=C1[H])[C@@]([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H])C([H])([H])C2([H])[H]
[H]OC1=C(O[H])C([H])=C2C(=C1[H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H])C([H])([H])[C@]2([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC1=C(Cl)C([H])=C2C(=C1[H])[C@@]([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C2([H])[H]
[H]OC1=C(Cl)C([H])=C2C(=C1[H])[C@@]([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H])C([H])([H])C2([H])[H]
[H]OC1=C(Cl)C([H])=C2C(=C1[H])[C@@]([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])N(C(=O)C([H])([H])C([H])([H])C([H])([H])N([H])[H])C([H])([H])C2([H])[H]
[H]OC1=C(Cl)C([H])=C2C(=C1[H])[C@@]([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])[H])C([H])([H])C2([H])[H]
[H]OC1=C(Cl)C([H])=C2C(=C1[H])[C@@]([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])C([H])([H])[H])C([H])([H])C2([H])[H]
[H]OC1=C(Br)C([H])=C2C(=C1[H])[C@@]([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H])C([H])([H])C2([H])[H]
[H]OC1=C(Cl)C([H])=C2C(=C1[H])[C@@]([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])[H])C([H])([H])C2([H])[H]
[H]OC1=C(Cl)C([H])=C2C(=C1[H])[C@@]([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])C([H])=O)C([H])([H])C2([H])[H]
[H]OC1=C(Cl)C([H])=C2C(=C1[H])[C@@]([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])C([H])([H])[H])C([H])([H])C2([H])[H]
[H]OC1=C(O[H])C([H])=C(C([H])=C1[H])[C@]([H])(C([H])([H])N([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C1=C(C2=C([H])C(=C([H])C([H])=C2N1C1=C([H])C([H])=C(F)C([H])=C1[H])C1=NC([H])=C([H])C([H])=N1)C1([H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])N2C(=O)OC([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]OC1=C(O[H])C2=C(C([H])=C1[H])C([H])([H])[C@@]1([H])N(C([H])([H])C3([H])C([H])([H])C3([H])[H])C([H])([H])C([H])([H])C3=C([H])C([H])=C([H])C2=C13
[H]OC1=C(O[H])C2=C(C([H])=C1[H])C([H])([H])[C@@]1([H])N([H])C([H])([H])C([H])([H])C3=C([H])C([H])=C([H])C2=C13
[H]OC1=C2C3=C4C(=C([H])C([H])=C3[H])C([H])([H])C([H])([H])N(C([H])([H])[H])[C@]4([H])C([H])([H])C2=C([H])C([H])=C1C([H])([H])[H]
[H]C1=C([H])C2=C(C([H])=C1[H])[C@]([H])(C1=C([H])C([H])=C([H])C([H])=C1C([H])=C2N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H])C([H])([H])[H]
[H]\C(=C1/C2=C([H])C([H])=C([H])C([H])=C2C([H])=C(N2C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C2([H])[H])C2=C1C([H])=C([H])C([H])=C2[H])C([H])([H])[H]
[H]OC1=C([H])C([H])=C([H])C2=C1C([H])([H])C([H])([H])[C@@]([H])(N(C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])N([H])[H])C2([H])[H]
[H]OC1=C([H])C2=C(C([H])=C1O[H])[C@](C1=C([H])C([H])=C([H])C([H])=C1[H])(C([H])([H])[H])[C@@](N([H])[H])(C([H])([H])[H])C2([H])[H]
[H]OC1=C([H])C2=C(C([H])=C1[H])[C@@]([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])[C@]([H])(N(C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[H])C2([H])[H]
[H]OC1=C([H])C2=C(C([H])=C1[H])C([H])([H])[C@@]([H])(N(C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[H])[C@]2([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC1=C([H])C2=C(C([H])=C1[H])C([H])([H])[C@@]([H])(N([H])[H])[C@]2([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC1=C([H])C2=C(C([H])=C1[H])C([H])([H])[C@@]([H])(N(C([H])([H])[H])C([H])([H])C([H])=C([H])[H])[C@]2([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC1=C([H])C2=C(C([H])=C1[H])[C@@]([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])[C@]([H])(N([H])[H])C2([H])[H]
[H]OC1=C([H])C2=C(C([H])=C1[H])[C@@]([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])[C@]([H])(N(C([H])([H])[H])C([H])([H])C([H])=C([H])[H])C2([H])[H]
[H]N1C2=C(N=C(N3C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C3([H])[H])C3=C1C([H])=C([H])C([H])=C3[H])C([H])=C(C([H])=N2)C([H])([H])[H]
[H]N1C2=C(N=C(N3C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C3([H])[H])C3=C1C([H])=C([H])N=C3[H])C([H])=C([H])C([H])=C2[H]
[H]N1C2=C(N=C(N3C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C3([H])[H])C3=C1C([H])=C([H])C(F)=C3[H])C([H])=C([H])C([H])=N2
[H]N1C2=C(N=C(N3C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C3([H])[H])C3=C1C([H])=C([H])C(=C3[H])C([H])([H])[H])C([H])=C([H])C([H])=N2
[H]N1C2=C(N=C(N3C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C3([H])[H])C3=C1C([H])=C(Cl)C([H])=C3[H])C([H])=C([H])C([H])=N2
[H]C(=O)N1C2=C(N=C(N3C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C3([H])[H])C3=C1C([H])=C([H])N=C3[H])C([H])=C([H])C([H])=C2[H]
[H]N1C2=C(C([H])=C([H])C([H])=N2)C(=NC2=C1C([H])=C([H])C([H])=C2[H])N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H]
[H]C1=NC2=C(N=C(N3C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C3([H])[H])C3=C(C([H])=C([H])C([H])=C3[H])N2C([H])([H])[H])C([H])=C1[H]
[H]N1C2=C(N=C(N3C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C3([H])[H])C3=C1C([H])=C([H])C(Cl)=C3[H])C([H])=C([H])C([H])=N2
[H]N1C2=C(N=C(N3C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C3([H])[H])C3=C1C([H])=C([H])C([H])=C3[H])C([H])=C([H])C([H])=N2
[H]OC1=C(Cl)C([H])=C2C(=C1[H])[C@]([H])(N(C([H])([H])[H])C([H])([H])C2([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC1=C(Cl)C([H])=C2C(=C1[H])[C@@]([H])(N(C([H])([H])[H])C([H])([H])C2([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC1=C(Cl)C([H])=C2C(=C1[H])[C@@]([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])N([H])C2([H])[H]
[H]OC1=C([H])C([H])=C2C(=C1[H])[C@]([H])(N(C([H])([H])[H])C([H])([H])C2([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC1=C(Cl)C([H])=C2C(=C1[H])[C@]([H])(N(C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C2([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC1=C([H])C2=C(C([H])=C1Br)C([H])([H])C([H])([H])N(C([H])([H])[H])[C@@]2([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC1=C(Cl)C([H])=C2C(=C1[H])[C@@]1([H])N(C([H])([H])C([H])([H])C3=C([H])C([H])=C([H])C([H])=C13)C([H])([H])C2([H])[H]
[H]OC1=C([H])C2=C(C([H])=C1O[H])[C@@]([H])(N(C([H])([H])[H])C([H])([H])C2([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC1=C(Cl)C([H])=C2C(=C1[H])[C@@]([H])(N([H])C([H])([H])C2([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC1=C([H])C2=C(C([H])=C1O[H])[C@]1([H])N(C([H])([H])C([H])([H])C3=C([H])C([H])=C([H])C([H])=C13)C([H])([H])C2([H])[H]
[H]OC1=C([H])C2=C(C([H])=C1[H])[C@]([H])(N(C([H])([H])[H])C([H])([H])C2([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC1=C(Cl)C([H])=C2C(=C1[H])[C@@]([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])N(C([H])([H])[H])C2([H])[H]
[H]OC1=C(O[H])C([H])=C2C(=C1[H])C([H])([H])C([H])([H])[C@@]1([H])N([H])C([H])([H])C3=C(SC([H])=C3C([H])([H])C([H])([H])C([H])([H])[H])[C@]21[H]
[H]OC1=C(O[H])C([H])=C2C(=C1[H])C([H])([H])C([H])([H])[C@]1([H])N([H])C([H])([H])C3=C(SC(=C3[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])[C@@]21[H]
[H]OC1=C(O[H])C([H])=C2C(=C1[H])C([H])([H])C([H])([H])[C@]1([H])N([H])C([H])([H])C3=C(C([H])=C(S3)C([H])([H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])[C@@]21[H]
[H]OC1=C(O[H])C([H])=C2C(=C1[H])C([H])([H])C([H])([H])[C@@]1([H])N([H])C([H])([H])C3=C(SC([H])=C3[C@]21[H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]OC1=C(O[H])C([H])=C2C(=C1[H])C([H])([H])C([H])([H])[C@]1([H])N([H])C([H])([H])C3=C(C([H])=C(S3)C([H])(C([H])([H])[H])C([H])([H])[H])[C@@]21[H]
[H]OC1=C([H])C([H])=C2C(=C1O[H])C([H])([H])C([H])([H])[C@]([H])(N([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C2([H])[H]
[H]OC1=C(O[H])C([H])=C2C(=C1[H])C([H])([H])C([H])([H])[C@]1([H])N([H])C([H])([H])C3=C(C([H])=C(S3)C3([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C3([H])[H])[C@@]21[H]
[H]OC1=C(O[H])C([H])=C2C(=C1[H])C([H])([H])C([H])([H])[C@]1([H])N([H])C([H])([H])C3=C(SC(Cl)=C3[H])[C@@]21[H]
[H]OC1=C(O[H])C([H])=C2C(=C1[H])C([H])([H])C([H])([H])[C@]1([H])N([H])C([H])([H])C3=C(SC([H])=C3[H])[C@@]21[H]
[H]OC1=C(O[H])C([H])=C2C(=C1[H])C([H])([H])C([H])([H])[C@@]1([H])N([H])C([H])([H])C3=C([H])SC([H])=C3[C@]21[H]
[H]OC1=C(O[H])C([H])=C2C(=C1[H])C([H])([H])C([H])([H])[C@]1([H])N([H])C([H])([H])C3=C(SC(=C3[H])C([H])([H])C([H])([H])[H])[C@@]21[H]
[H]OC1=C(O[H])C([H])=C2C(=C1[H])C([H])([H])C([H])([H])[C@]1([H])N([H])C([H])([H])C3=C(C([H])=C([H])S3)[C@@]21[H]
[H]OC1=C(O[H])C([H])=C2C(=C1[H])C([H])([H])C([H])([H])[C@]1([H])N([H])C([H])([H])C3=C(SC(=C3[H])C([H])([H])[H])[C@@]21[H]
[H]OC1=C(O[H])C([H])=C2C(=C1[H])C([H])([H])C([H])([H])[C@]1([H])N([H])C([H])([H])C3=C(C([H])=C(Cl)S3)[C@@]21[H]
[H]OC1=C(O[H])C([H])=C2C(=C1[H])C([H])([H])C([H])([H])[C@]1([H])N([H])C([H])([H])C3=C(SC(=C3[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])[C@@]21[H]
[H]OC1=C(O[H])C([H])=C2C(=C1[H])C([H])([H])C([H])([H])[C@]1([H])N([H])C([H])([H])C3=C(SC(=C3[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])[C@@]21[H]
[H]OC1=C(O[H])C([H])=C2C(=C1[H])C([H])([H])C([H])([H])[C@]1([H])N([H])C([H])([H])C3=C(C([H])=C(S3)C3=C([H])C([H])=C([H])C([H])=C3[H])[C@@]21[H]
[H]OC1=C(O[H])C([H])=C2C(=C1[H])C([H])([H])C([H])([H])[C@]1([H])N([H])C([H])([H])C3=C(C([H])=C(S3)C3=C([H])C(=C([H])C([H])=C3[H])C([H])([H])[H])[C@@]21[H]
[H]OC1=C(O[H])C([H])=C2C(=C1[H])C([H])([H])C([H])([H])[C@]1([H])N([H])C([H])([H])C3=C(C([H])=C(S3)C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])[C@@]21[H]
[H]C1=C([H])C([H])=C2C(=C1[H])C([H])([H])C([H])([H])O[C@]2([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C([H])C([H])=C(OC([H])([H])[H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]C1=C([H])C(=C([H])C([H])=C1F)N1C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])[C@@]2([H])OC([H])([H])C([H])([H])C3=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C([H])=C23)C([H])([H])C1([H])[H]
[H]OC1=C([H])C([H])=C([H])C(=C1[H])[C@]1(C([H])([H])[H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])[C@]([H])(O[H])C2([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])[C@]1([H])C([H])([H])[H]
[H]C1=C2C(=C([H])C(Cl)=C1[H])[C@@]([H])(N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H])C([H])([H])[C@@]2([H])C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]C1=C(C2=C([H])C(Cl)=C([H])C([H])=C2[C@]1([H])C1=C([H])C([H])=C(F)C([H])=C1[H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H]
[H]C1=C(C2=C([H])C(Cl)=C([H])C([H])=C2N1C1=C([H])C([H])=C(F)C([H])=C1[H])C1=C([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H]
[H]C1=C(C2=C([H])C(Cl)=C([H])C([H])=C2[C@@]1([H])C1=C([H])C([H])=C(F)C([H])=C1[H])C1=C([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H]
[H]C1=C([H])C([H])=C2C(=C1[H])C([H])([H])C([H])([H])O[C@]2([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C([H])C([H])=C(F)C([H])=C2[H])C([H])([H])C1([H])[H]
[H]OC1=C2C3=C4C(=C([H])C([H])=C3[H])C([H])([H])C([H])([H])N(C([H])([H])[H])[C@]4([H])C([H])([H])C2=C([H])C([H])=C1C([H])([H])C([H])([H])[H]
[H]C1=C([H])C2=C3C(=C1[H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])[H])[C@]3([H])C([H])([H])C1=C([H])C([H])=C(OS(=O)(=O)C(F)(F)F)C(OC([H])([H])[H])=C21
[H]C1=C([H])C2=C3C(=C1[H])C([H])([H])C([H])([H])N(C([H])([H])[H])[C@]3([H])C([H])([H])C1=C([H])C([H])=C(OS(=O)(=O)C(F)(F)F)C(OC([H])([H])[H])=C21
[H]C([H])=C([H])C1=C([H])C([H])=C2C(=C1OC([H])([H])[H])C1=C3C(=C([H])C([H])=C1[H])C([H])([H])C([H])([H])N(C([H])([H])[H])[C@]3([H])C2([H])[H]
[H]C1=C([H])C2=C3C(=C1[H])C([H])([H])C([H])([H])N(C([H])(C([H])([H])[H])C([H])([H])[H])[C@]3([H])C([H])([H])C1=C([H])C([H])=C(C(OC([H])([H])[H])=C21)C([H])([H])[H]
[H]OC1=C2C3=C4C(=C([H])C([H])=C3[H])C([H])([H])C([H])([H])N(C([H])([H])[H])[C@]4([H])C([H])([H])C2=C([H])C([H])=C1C(=O)C([H])([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1C([H])([H])C([H])([H])C2=C([H])C([H])=C([H])C3=C2[C@@]1([H])C([H])([H])C1=C([H])C([H])=C(C(OC([H])([H])[H])=C31)C([H])([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])OC1=C([H])C(=C([H])C([H])=C1OC([H])([H])[H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]C1=C([H])C2=C3C(=C1[H])C([H])([H])C([H])([H])N(C([H])([H])[H])[C@]3([H])C([H])([H])C1=C([H])C([H])=C(C(OC([H])([H])[H])=C21)C([H])([H])[H]
[H]OC1=C2C3=C4C(=C([H])C([H])=C3[H])C([H])([H])C([H])([H])N(C([H])([H])[H])[C@]4([H])C([H])([H])C2=C([H])C([H])=C1C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])OC1=C([H])C(=C([H])C([H])=C1OC([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]C1=C([H])C(C#N)=C2C3=C4C(=C([H])C([H])=C3[H])C([H])([H])C([H])([H])N(C([H])([H])[H])[C@]4([H])C([H])([H])C2=C1[H]
[H]C1=C([H])C(OC([H])([H])[H])=C2C3=C4C(=C([H])C([H])=C3[H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])[H])[C@]4([H])C([H])([H])C2=C1[H]
[H]N1C([H])([H])C([H])([H])C2=C([H])C([H])=C([H])C3=C2[C@@]1([H])C([H])([H])C1=C([H])C([H])=C([H])C(OC([H])([H])[H])=C31
[H]OC1=C2C3=C4C(=C([H])C([H])=C3[H])C([H])([H])C([H])([H])N([H])[C@]4([H])C([H])([H])C2=C([H])C([H])=C1[H]
[H]C([H])=C([H])C1=C2C3=C4C(=C([H])C([H])=C3[H])C([H])([H])C([H])([H])N(C([H])([H])[H])[C@]4([H])C([H])([H])C2=C([H])C([H])=C1[H]
[H]C1=C([H])C([H])=C(C(OC([H])([H])[H])=C1[H])C1=C2C3=C4C(=C([H])C([H])=C3[H])C([H])([H])C([H])([H])N(C([H])([H])[H])[C@]4([H])C([H])([H])C2=C([H])C([H])=C1[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C1=C2C3=C4C(=C([H])C([H])=C3[H])C([H])([H])C([H])([H])N(C([H])([H])[H])[C@]4([H])C([H])([H])C2=C([H])C([H])=C1[H]
[H]C1=C([H])C(OS(=O)(=O)C(F)(F)F)=C2C3=C4C(=C([H])C([H])=C3[H])C([H])([H])C([H])([H])N(C([H])([H])[H])[C@]4([H])C([H])([H])C2=C1[H]
[H]C1=C([H])C(C(=O)C([H])([H])[H])=C2C3=C4C(=C([H])C([H])=C3[H])C([H])([H])C([H])([H])N(C([H])([H])[H])[C@]4([H])C([H])([H])C2=C1[H]
[H]C1=C([H])C2=C3C(=C1[H])C([H])([H])C([H])([H])N(C([H])([H])[H])[C@]3([H])C([H])([H])C1=C([H])C([H])=C([H])C(=C21)C([H])([H])C([H])([H])[H]
[H]C1=C([H])C([H])=C2C(=C1[H])C1=C3C(=C([H])C([H])=C1[H])C([H])([H])C([H])([H])N(C([H])([H])[H])[C@]3([H])C2([H])[H]
[H]OC1=C2C3=C4C(=C([H])C([H])=C3[H])C([H])([H])C([H])([H])N(C([H])([H])C3=C([H])C([H])=C([H])C([H])=C3[H])[C@]4([H])C([H])([H])C2=C([H])C([H])=C1[H]
[H]C1=C([H])C2=C3C(=C1[H])C([H])([H])C([H])([H])N(C([H])([H])[H])[C@]3([H])C([H])([H])C1=C([H])C([H])=C([H])C(=C21)C([H])([H])[H]
[H]N([H])C(=O)C1=C2C3=C4C(=C([H])C([H])=C3[H])C([H])([H])C([H])([H])N(C([H])([H])[H])[C@]4([H])C([H])([H])C2=C([H])C([H])=C1[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])OC1=C([H])C([H])=C(Cl)C([H])=C1C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])OC1=C(OC([H])([H])[H])C([H])=C([H])C([H])=C1C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]N1C([H])([H])C([H])([H])C2=C([H])C([H])=C([H])C3=C2[C@@]1([H])C([H])([H])C1=C([H])C([H])=C(C(OC([H])([H])[H])=C31)C([H])([H])[H]
[H]C1=C([H])C2=C3C(=C1[H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])[H])[C@]3([H])C([H])([H])C1=C([H])C([H])=C(C(OC([H])([H])[H])=C21)C([H])([H])[H]
[H]OC1=C2C3=C4C(=C([H])C([H])=C3[H])C([H])([H])C([H])([H])N(C([H])([H])C3=C([H])C([H])=C([H])C([H])=C3[H])[C@]4([H])C([H])([H])C2=C([H])C([H])=C1C([H])([H])[H]
[H]C1=C([H])C2=C3C(=C1[H])C([H])([H])C([H])([H])N(C([H])([H])[H])[C@]3([H])C([H])([H])C1=C([H])C([H])=C(C(OC([H])([H])[H])=C21)C([H])([H])C([H])([H])[H]
[H]OC([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C(\[H])=C2/C3=C(SC4=C2C([H])=C(C([H])=C4[H])C(F)(F)F)C([H])=C([H])C([H])=C3[H])C([H])([H])C1([H])[H]
[H]C1=C([H])N2C(SC3=C([H])C([H])=C(Cl)C([H])=C3[C@]([H])(N3C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C3([H])[H])C2([H])[H])=C1[H]
[H]N1C2=C(C([H])=C(S2)C([H])([H])[H])C(=NC2=C([H])C([H])=C([H])C([H])=C12)N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H]
[H]C1=C([H])N2C(SC3=C([H])C([H])=C([H])C([H])=C3[C@]([H])(N3C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C3([H])[H])C2([H])[H])=C1[H]
[H]OC1=C(Br)C([H])=C2C(=C1[H])[C@@]([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])N(C([H])([H])C(\[H])=C(/[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C2([H])[H]
[H]OC1=C(Cl)C([H])=C2C(=C1[H])[C@@]([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])N(C([H])([H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])N(C([H])([H])[H])C([H])([H])[H])C([H])([H])C2([H])[H]
[H]OC1=C(Cl)C([H])=C2C(=C1[H])[C@@]([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])N(C([H])([H])C(\[H])=C(/[H])C1=C([H])C([H])=C(C([H])=C1[H])N(C([H])([H])[H])C([H])([H])[H])C([H])([H])C2([H])[H]
[H]C1=C([H])C2=C(C([H])=C1[H])C1=C(S2)[C@]([H])(C2=C([H])C([H])=C([H])C(=C2[H])[N+]([O-])=O)C([H])([H])N(C([H])([H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]C1=C([H])C2=C(C([H])=C1[H])C1=C(S2)[C@]([H])(C2=C([H])C([H])=C([H])C(Br)=C2[H])C([H])([H])N(C([H])([H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])[C@]1([H])C2=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C([H])=C2C([H])([H])C([H])([H])N(C([H])([H])[H])C1([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])[C@@]1([H])C2=C(C3=C(S2)C([H])=C([H])C([H])=C3[H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])[H])C1([H])[H]
[H]OC1=C(Br)C([H])=C2C(=C1[H])[C@@]([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])N(C([H])([H])C(\[H])=C(/[H])C1=C([H])C([H])=C(C([H])=C1[H])N(C([H])([H])[H])C([H])([H])[H])C([H])([H])C2([H])[H]
[H]C1=C([H])C2=C3C(=C1[H])C([H])([H])C([H])([H])N(C([H])([H])[H])[C@]3([H])C([H])([H])C1=C([H])C([H])=C(C(=O)C([H])([H])[H])C(OC([H])([H])[H])=C21
[H]OC1=C2C3=C4C(=C([H])C([H])=C3[H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])[H])[C@]4([H])C([H])([H])C2=C([H])C([H])=C1C([H])([H])[H]
[H]OC1=C([H])C([H])=C([H])C2=C1C([H])([H])C([H])([H])[C@@]1([H])N(C([H])([H])C(\[H])=C(/[H])I)C([H])([H])C([H])([H])C([H])([H])[C@]21[H]
[H]\C(I)=C(\[H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])[C@]2([H])C([H])([H])C3=C(OC([H])([H])[H])C([H])=C([H])C([H])=C3C([H])([H])[C@@]12[H]
[H]\C(I)=C(\[H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])[C@@]2([H])C([H])([H])C3=C([H])C([H])=C([H])C([H])=C3C([H])([H])[C@@]12[H]
[H]C1([H])N(C1([H])[H])P(=O)(N1C([H])([H])C1([H])[H])N1C([H])([H])C1([H])[H]
[H]OC1=C2C(=C([H])C([H])=C1[H])C([H])([H])[C@]1([H])N(C([H])([H])C#C[H])C([H])([H])C([H])([H])C([H])([H])[C@]1([H])C2([H])[H]
[H]N([H])N1C(SC([H])([H])C([H])([H])C([H])([H])N2C([H])([H])C([H])([H])N(C3=C([H])C([H])=C([H])C([H])=C3OC([H])([H])[H])C([H])([H])C2([H])[H])=NC2=C(C(=C(S2)C([H])([H])[H])C([H])([H])[H])C1=O
[H]N([H])N1C(SC([H])([H])C([H])([H])C([H])([H])N2C([H])([H])C([H])([H])N(C3=NC([H])=C([H])C([H])=N3)C([H])([H])C2([H])[H])=NC2=C(C(=C(S2)C([H])([H])[H])C([H])([H])[H])C1=O
[H]N([H])N1C(SC([H])([H])C([H])([H])C([H])([H])N2C([H])([H])C([H])([H])C([H])(C3=C([H])C([H])=C([H])C([H])=C3OC([H])([H])[H])C([H])([H])C2([H])[H])=NC2=C(C(=C(S2)C([H])([H])[H])C([H])([H])[H])C1=O
[H]C1=C([H])C([H])=C(C#CC([H])([H])C([H])([H])N2C([H])([H])C([H])=C(C3=C([H])C([H])=C([H])C([H])=C3[H])C([H])([H])C2([H])[H])C([H])=N1
[H]OC1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[C@@]1([H])N([H])C([H])([H])C([H])([H])C2=C([H])C(OC([H])([H])[H])=C(O[H])C([H])=C12
[H]N1C2=C([H])C([H])=C(OS(=O)(=O)C(F)(F)F)C([H])=C2N=C(N2C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C2([H])[H])C2=C1C([H])=C([H])C([H])=C2[H]
[H]N1C2=C([H])C([H])=C([H])C([H])=C2N=C(N2C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C2([H])[H])C2=C1C([H])=C([H])C(OS(=O)(=O)C(F)(F)F)=C2[H]
[H]N1C2=C([H])C([H])=C([H])C([H])=C2N=C(N2C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C2([H])[H])C2=C1C([H])=C([H])C(OC([H])([H])[H])=C2[H]
[H]OC1=C([H])C([H])=C2N([H])C3=C(C([H])=C([H])C([H])=C3[H])C(=NC2=C1[H])N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H]
[H]O[C@@]1(C([H])([H])C([H])([H])N2C([H])([H])[C@]3([H])C4=C(C([H])=C([H])C([H])=C4[H])C([H])([H])C([H])([H])C4=C3C(=C([H])C([H])=C4[H])[C@@]2([H])C1([H])[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]N1C2=C([H])C([H])=C([H])C([H])=C2C2=C1C([H])([H])C1=C(C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C2([H])[H]
[H]N1C2=C(C([H])=C([H])C([H])=C2[H])C2=C1C([H])([H])C1=C(C([H])=C(OC([H])([H])[H])C(OC([H])([H])[H])=C1[H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C2([H])[H]
[H]N1C2=C(C([H])=C([H])C([H])=C2[H])C2=C1C([H])([H])C1=C(C3=C(N1[H])C([H])=C([H])C([H])=C3[H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C2([H])[H]
[H]OC1=C([H])C2=C(N([H])C3=C([H])C([H])=C([H])C([H])=C3N=C2N2C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C2([H])[H])C([H])=C1[H]
[H]N1C2=C([H])C([H])=C(OC([H])([H])[H])C([H])=C2N=C(N2C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C2([H])[H])C2=C1C([H])=C([H])C([H])=C2[H]
[H]C1=C([H])C2=C3C(=C1[H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[C@@]3([H])C([H])([H])N2C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]C1=C([H])C(=C([H])C([H])=C1F)N1C2=C3C(=C([H])C(OC([H])([H])[H])=C2OC([H])([H])[H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[C@@]3([H])C1([H])[H]
[H]OC1=C(O[H])C2=C3C(=C1[H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[C@@]3([H])C([H])([H])N2C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]C1=C([H])C2=C(C(=C1[H])C([H])([H])[H])[C@]([H])(C([H])([H])N(C([H])([H])[H])C([H])([H])[H])C([H])([H])N2C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]OC1=C(O[H])C2=C3C(=C([H])N2C2=C([H])C([H])=C(F)C([H])=C2[H])C([H])([H])N(C([H])([H])[H])C([H])([H])C([H])([H])C3=C1[H]
[H]N1C2=C3C(=C([H])C([H])=C2[H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[C@]3([H])C1([H])[H]
[H]C1=C2C3=C(N1C1=C([H])C([H])=C(F)C([H])=C1[H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C([H])=C3C([H])([H])C([H])([H])N(C([H])([H])[H])C2([H])[H]
[H]C1=C2C3=C(C([H])=C([H])C([H])=C3C([H])([H])C([H])([H])N(C([H])([H])[H])C2([H])[H])N1C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]N1C([H])([H])C([H])([H])C2=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C3=C2[C@]([H])(C([H])([H])N3C2=C([H])C([H])=C(F)C([H])=C2[H])C1([H])[H]
[H]N1C([H])([H])C([H])([H])C2=C([H])C([H])=C([H])C3=C2[C@]([H])(C([H])([H])N3C2=C([H])C([H])=C(F)C([H])=C2[H])C1([H])[H]
[H]C1=C([H])C(=C([H])C([H])=C1F)N1C2=C3C(=C(Cl)C(OC([H])([H])[H])=C2OC([H])([H])[H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[C@]3([H])C1([H])[H]
[H]N1C([H])=C2C3=C(C([H])=C([H])C([H])=C13)C([H])([H])C([H])([H])N(C([H])([H])[H])C2([H])[H]
[H]C1=C([H])C(F)=C([H])C2=C1C(=NO2)C1([H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C2=C(N=C3N(C2=O)C([H])([H])C([H])([H])C([H])([H])C3([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N1C([H])=C2C3=C1C([H])=C([H])C([H])=C3[C@@]1([H])C([H])([H])[C@@]([H])(C([H])([H])N3C(=O)N([H])C(=O)C3([H])[H])C([H])([H])N(C([H])([H])[H])[C@]1([H])C2([H])[H]
[H]N(C(=O)OC([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[C@@]1([H])C([H])([H])N(C([H])([H])[H])[C@]2([H])C([H])([H])C3=C([H])N([H])C4=C3C(=C([H])C([H])=C4[H])[C@@]2([H])C1([H])[H]
[H]N(C(=O)N(C(=O)[C@@]1([H])C([H])([H])N(C([H])([H])[H])[C@]2([H])C([H])([H])C3=C([H])N([H])C4=C3C(=C([H])C([H])=C4[H])[C@@]2([H])C1([H])[H])C([H])([H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])[H]
[H]N1C([H])=C2C3=C1C(=C([H])C([H])=C3[C@@]1([H])C([H])([H])[C@@]([H])(C([H])([H])[H])C([H])([H])N(C([H])([H])[H])[C@]1([H])C2([H])[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[C@@]1([H])C([H])([H])N(C([H])([H])[H])[C@]2([H])C([H])([H])C3=C([H])N([H])C4=C3C(=C([H])C([H])=C4[H])[C@@]2([H])C1([H])[H]
[H]N1C([H])=C2C3=C1C(=C([H])C([H])=C3[C@@]1([H])C([H])([H])[C@@]([H])(C([H])([H])N3C(=O)N([H])C(=O)C3([H])[H])C([H])([H])N(C([H])([H])[H])[C@]1([H])C2([H])[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)[C@@]1([H])C([H])([H])N(C([H])([H])[H])[C@]2([H])C([H])([H])C3=C([H])N([H])C4=C3C(=C([H])C([H])=C4[H])[C@@]2([H])C1([H])[H])C1=NC([H])=C([H])S1
[H]N(C(=O)[C@@]1([H])C([H])([H])N(C([H])([H])[H])[C@]2([H])C([H])([H])C3=C([H])N([H])C4=C3C(=C([H])C(=C4[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])[C@@]2([H])C1([H])[H])C1=C([H])C([H])=C(Cl)N=N1
[H]N(C(=S)N([H])C([H])([H])[C@@]1([H])C([H])([H])N(C([H])([H])[H])[C@]2([H])C([H])([H])C3=C([H])N([H])C4=C3C(=C([H])C([H])=C4C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])[C@@]2([H])C1([H])[H])C(=O)C([H])([H])[H]
[H]N(C(=S)N([H])C([H])([H])[C@@]1([H])C([H])([H])N(C([H])([H])[H])[C@]2([H])C([H])([H])C3=C([H])N([H])C4=C3C(=C([H])C([H])=C4[H])[C@@]2([H])C1([H])[H])C(=O)C([H])([H])[H]
[H]N1C([H])=C2C3=C1C([H])=C([H])C([H])=C3[C@@]1([H])C([H])([H])[C@@]([H])(C([H])([H])[H])C([H])([H])N(C([H])([H])[H])[C@]1([H])C2([H])[H]
[H]N(C(=O)[C@@]1([H])C([H])([H])N(C([H])([H])[H])[C@]2([H])C([H])([H])C3=C([H])N([H])C4=C3C(=C([H])C([H])=C4C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])[C@@]2([H])C1([H])[H])C1=C([H])C([H])=C(Cl)N=N1
[H]N(C(=O)C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[C@@]1([H])C([H])([H])N(C([H])([H])[H])[C@]2([H])C([H])([H])C3=C([H])N([H])C4=C3C(=C([H])C(=C4[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])[C@@]2([H])C1([H])[H]
[H]N(C(=O)[C@@]1([H])C([H])([H])N(C([H])([H])[H])[C@]2([H])C([H])([H])C3=C([H])N([H])C4=C3C(=C([H])C([H])=C4[H])[C@@]2([H])C1([H])[H])C1=C([H])C([H])=C(Cl)N=N1
[H]N1C([H])=C2C3=C1C([H])=C(C([H])=C3[C@@]1([H])C([H])([H])[C@@]([H])(C([H])([H])N3C(=O)N([H])C(=O)C3([H])[H])C([H])([H])N(C([H])([H])[H])[C@]1([H])C2([H])[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]N1C2=C([H])C([H])=C(Cl)C([H])=C2N=C(N2C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C2([H])[H])C2=C1C([H])=C([H])C(OS(=O)(=O)C(F)(F)F)=C2[H]
[H]C1=C([H])C2=C(C([H])=C1[H])C([H])([H])N(C2=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])[C@]([H])(C2=C([H])C([H])=C(Cl)C([H])=C2[H])C1([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])[C@]1([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])C([H])([H])N2C(=O)C3=C(C([H])=C([H])C([H])=C3[H])C2([H])[H])C([H])([H])C1([H])[H]
[H]C1=C([H])C2=C(C([H])=C1[H])S(=O)(=O)N(C2=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])[C@]([H])(C2=C([H])C([H])=C(F)C([H])=C2[H])C1([H])[H]
[H]C1=C([H])C2=C(C([H])=C1[H])S(=O)(=O)N(C2=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])[C@]([H])(C2=C([H])C([H])=C(Cl)C([H])=C2[H])C1([H])[H]
[H]OC([H])([H])C1=C([H])OC2=C(C([H])=C([H])C(OC([H])([H])C([H])([H])C([H])([H])N3C([H])([H])C([H])([H])C([H])(C4=NOC5=C([H])C(F)=C([H])C([H])=C45)C([H])([H])C3([H])[H])=C2[H])C1=O
[H]C1=C([H])C([H])=C2N=C(N3C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C3([H])[H])C3=C(OC2=C1[H])C([H])=C([H])C(OS(=O)(=O)C(F)(F)F)=C3[H]
[H]C1=C([H])C([H])=C2N=C(N3C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C3([H])[H])C3=C(SC2=C1[H])C([H])=C([H])C(OS(=O)(=O)C(F)(F)F)=C3[H]
[H]N1C2=C([H])C([H])=C([H])C([H])=C2N=C(N2C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C2([H])[H])C2=C1C([H])=C([H])C(OS(=O)(=O)C([H])([H])[H])=C2[H]
[H]OC1=C([H])C2=C(C([H])=C1OC([H])([H])[H])C1=C(OC([H])([H])[H])C(O[H])=C([H])C3=C1[C@@]([H])(N(C([H])([H])[H])C([H])([H])C3([H])[H])C2([H])[H]
[H]OC1=C([H])C2=C(C([H])=C1OC([H])([H])[H])C1=C3C(=C(I)C(O[H])=C1OC([H])([H])[H])C([H])([H])C([H])([H])N(C([H])([H])[H])[C@@]3([H])C2([H])[H]
[H]OC1=C([H])C2=C(C([H])=C1OC([H])([H])[H])C1=C3C(=C(Cl)C(O[H])=C1OC([H])([H])[H])C([H])([H])C([H])([H])N(C([H])([H])[H])[C@@]3([H])C2([H])[H]
[H]OC1=C(Br)C2=C(C([H])=C1OC([H])([H])[H])C1=C3C(=C(Br)C(O[H])=C1OC([H])([H])[H])C([H])([H])C([H])([H])N(C([H])([H])[H])[C@@]3([H])C2([H])[H]
[H]OC1=C([H])C2=C(C([H])=C1OC([H])([H])[H])C1=C3C(=C(Br)C(O[H])=C1OC([H])([H])[H])C([H])([H])C([H])([H])N(C([H])([H])[H])[C@@]3([H])C2([H])[H]
[H]OC1=C(O[H])C([H])=C2C(=C1[H])C([H])([H])C([H])([H])N([H])[C@@]2([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)C1=C2C(OC([H])([H])[C@@]([H])(N(C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[H])C2([H])[H])=C([H])C([H])=C1[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N([H])C(=O)C1=C2C(OC([H])([H])[C@]([H])(N(C([H])([H])C([H])([H])C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])C2([H])[H])=C([H])C([H])=C1[H]
[H]N([H])C(=O)C1=C2C(OC([H])([H])[C@@]([H])(N([H])C([H])(C([H])([H])[H])C([H])([H])[H])C2([H])[H])=C([H])C([H])=C1[H]
[H]N([H])C(=O)C1=C2C(OC([H])([H])[C@@]([H])(N(C([H])([H])C([H])([H])C([H])([H])[H])C3([H])C([H])([H])C([H])([H])C([H])([H])C3([H])[H])C2([H])[H])=C([H])C([H])=C1[H]
[H]N([H])C(=O)C1=C2C(OC([H])([H])[C@@]([H])(N([H])C([H])([H])C([H])([H])C([H])([H])[H])C2([H])[H])=C([H])C([H])=C1[H]
[H]N1C2=C(C(=C([H])S2)C2=C([H])C([H])=C([H])C([H])=C2[H])C(=O)N(C1=O)C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C(OC([H])([H])[H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])[C@]2([H])C([H])([H])C3=C(OC([H])([H])[H])C([H])=C([H])C([H])=C3C([H])([H])[C@@]12[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])[C@]2([H])C([H])([H])C3=C([H])C([H])=C([H])C([H])=C3C([H])([H])[C@@]12[H]
[H]C1=C([H])N2C(SC3=C([H])C([H])=C(F)C([H])=C3[C@]([H])(N3C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])[H])C([H])([H])C3([H])[H])C2([H])[H])=C1[H]
[H]C1=C([H])N2C(SC3=C([H])C([H])=C(Br)C([H])=C3[C@]([H])(N3C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C3([H])[H])C2([H])[H])=C1[H]
[H]OC([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])[C@@]1([H])C2=C([H])C(Cl)=C([H])C([H])=C2SC2=C([H])C([H])=C([H])N2C1([H])[H]
[H]C1=C([H])N2C(SC3=C([H])C([H])=C(Cl)C([H])=C3[C@]([H])(N3C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C([H])([H])C3([H])[H])C2([H])[H])=C1[H]
[H]OC([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])[C@@]1([H])C2=C([H])C(F)=C([H])C([H])=C2SC2=C([H])C([H])=C([H])N2C1([H])[H]
[H]OC([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])[C@@]1([H])C2=C([H])C(Br)=C([H])C([H])=C2SC2=C([H])C([H])=C([H])N2C1([H])[H]
[H]OC1=C([H])C([H])=C2C(=C1O[H])C([H])([H])C1=C3C(=C([H])C([H])=C1[H])C([H])([H])N([H])C([H])([H])[C@]23[H]
[H]OC1=C([H])C([H])=C2C(=C1O[H])C([H])([H])C([H])([H])[C@]([H])(N(C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[H])C2([H])[H]
[H]OC1=C(Cl)C([H])=C(Cl)C(OC([H])([H])[H])=C1C(=O)N([H])C([H])([H])[C@@]1([H])N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C1([H])[H]
[H]OC1=C(I)C([H])=C([H])C(OC([H])([H])[H])=C1C(=O)N([H])C([H])([H])[C@@]1([H])N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C1([H])[H]
[H]C1=C2N(C3=C1C([H])=C([H])C([H])=C3[H])C([H])([H])C([H])([H])N(C2=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C([H])C([H])=C([H])C([H])=C2OC([H])([H])[H])C([H])([H])C1([H])[H]
[H]N(C(=O)C1=C([H])C2=C([H])C([H])=C([H])C([H])=C2C([H])=N1)C([H])([H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C([H])C([H])=C([H])C([H])=C2OC([H])([H])[H])C([H])([H])C1([H])[H]
[H]N(C(=O)C1=C([H])C2=C([H])C([H])=C([H])C([H])=C2C([H])=N1)C([H])([H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C([H])C([H])=C(Cl)C([H])=C2Cl)C([H])([H])C1([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C2C([H])=C([H])C([H])=C([H])C2=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C([H])C([H])=C([H])C([H])=C2OC([H])([H])[H])C([H])([H])C1([H])[H]
[H]N(C(=O)C1=C([H])C2=C(N1[H])C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C(OC([H])([H])[H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N(C(=O)C1=C([H])C2=C(O1)C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C([H])C([H])=C(Cl)C([H])=C2Cl)C([H])([H])C1([H])[H]
[H]N(C(=O)C1=NC2=C([H])C([H])=C([H])C([H])=C2N=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C([H])C([H])=C([H])C([H])=C2OC([H])([H])[H])C([H])([H])C1([H])[H]
[H]N(C(=O)C1=C([H])C2=C(O1)C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C(OC([H])([H])[H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N(C(=O)C1=NC2=C([H])C([H])=C([H])C([H])=C2C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C([H])C([H])=C([H])C([H])=C2OC([H])([H])[H])C([H])([H])C1([H])[H]
[H]N(C(=O)C1=NC2=C([H])C([H])=C([H])C([H])=C2N2C([H])=C([H])C([H])=C12)C([H])([H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C([H])C([H])=C([H])C([H])=C2OC([H])([H])[H])C([H])([H])C1([H])[H]
[H]N(C(=O)C1=C([H])C2=C(O1)C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C([H])C([H])=C(Cl)C(Cl)=C2[H])C([H])([H])C1([H])[H]
[H]N1C([H])([H])C2=C([H])C([H])=C([H])C3=C2N(C2=C3C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]C1=C2N(C(=C1[H])C([H])([H])[H])C([H])([H])C1=C(C([H])=C([H])C([H])=C1[H])C([H])=C2N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H]
[H]C1=C([H])N2C([H])=C(N3C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C3([H])[H])C3=C([H])C([H])=C([H])C([H])=C3SC2=C1[H]
[H]C1=C([H])N2C(=C1[H])C(=C([H])C1=C(C([H])=C([H])C([H])=C1[H])C2([H])[H])N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H]
[H]C1=C([H])C2=C(C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[C@]1([H])N2C([H])([H])C([H])([H])N(C([H])([H])[H])C1([H])[H]
[H]C1=C([H])C2=C(S1)SC1=C([H])C([H])=C([H])N1C([H])=C2N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H]
[H]C1=C([H])N2C(=C1[H])C(=C([H])C1=C(C([H])=C([H])C(Cl)=C1[H])C2([H])[H])N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H]
[H]C1=C([H])C([H])=C2C(=N1)N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[C@]1([H])C1=C(C([H])=C([H])C([H])=C1[H])C2([H])[H]
[H]C1=C([H])[C@]2([H])C([H])([H])[C@@]1([H])[C@@]1([H])C(=O)N(OC([H])([H])C([H])([H])C([H])([H])N3C([H])([H])C([H])([H])N(C4=C([H])C(=C([H])C([H])=C4[H])C(F)(F)F)C([H])([H])C3([H])[H])C(=O)[C@@]21[H]
[H]OC1=C(OC([H])([H])[H])C2=C3C(=C1Br)C([H])([H])C([H])([H])N(C([H])([H])[H])[C@@]3([H])C([H])([H])C1=C2C([H])=C(OC([H])([H])[H])C(OC([H])([H])[H])=C1[H]
[H]OC1=C(O[H])C2=C3C(=C1[H])C([H])([H])C([H])([H])N(C([H])([H])[H])[C@@]3([H])C([H])([H])C1=C(C([H])=C([H])C([H])=C1[H])C2([H])[H]
[H]OC1=C([H])C2=C3C(=C1OC([H])([H])[H])C1=C([H])C(OC([H])([H])[H])=C(O[H])C([H])=C1C([H])([H])[C@]3([H])N([H])C([H])([H])C2([H])[H]
[H]N1C([H])([H])C([H])([H])C2=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C3=C2[C@@]1([H])C([H])([H])C1=C(C([H])=C([H])C([H])=C1[H])C3([H])[H]
[H]OC1=C(OC([H])([H])[H])C2=C3C(=C1I)C([H])([H])C([H])([H])N(C([H])([H])[H])[C@@]3([H])C([H])([H])C1=C2C([H])=C(OC([H])([H])[H])C(OC([H])([H])[H])=C1[H]
[H]OC1=C([H])C([H])=C2C3=C1OC1=C(C([H])=C([H])C(OC([H])([H])[H])=C1O[H])C([H])([H])[C@]3([H])N(C([H])([H])[H])C([H])([H])C2([H])[H]
[H]OC1=C([H])C2=C(OC3=C4C(=C([H])C([H])=C3[H])C([H])([H])C([H])([H])N(C([H])([H])[H])[C@@]4([H])C2([H])[H])C([H])=C1[H]
[H]C1=C([H])C2=C(C([H])=C1[H])C([H])([H])[C@]1([H])N(C([H])([H])[H])C([H])([H])C([H])([H])C3=C([H])C(OC([H])([H])[H])=C([H])C(=C13)C2([H])[H]
[H]C1=C(OC([H])([H])[H])C(OC([H])([H])[H])=C([H])C2=C1C1=C3C(=C(Br)C(OC([H])([H])[H])=C1OC([H])([H])[H])C([H])([H])C([H])([H])N(C([H])([H])[H])[C@@]3([H])C2([H])[H]
[H]OC1=C([H])C([H])=C2C3=C1OC1=C(C([H])=C(OC([H])([H])[H])C(OC([H])([H])[H])=C1[H])C([H])([H])[C@]3([H])N(C([H])([H])[H])C([H])([H])C2([H])[H]
[H]C1=C(OC([H])([H])[H])C(OC([H])([H])[H])=C([H])C2=C1C1=C3C(=C(I)C(OC([H])([H])[H])=C1OC([H])([H])[H])C([H])([H])C([H])([H])N(C([H])([H])[H])[C@@]3([H])C2([H])[H]
[H]N1C([H])([H])C([H])([H])C2=C(OC([H])([H])[H])C3=C(OC([H])([H])O3)C3=C2[C@@]1([H])C([H])([H])C1=C3C([H])=C([H])C([H])=C1[H]
[H]OC1=C([H])C2=C3C(=C1[H])C([H])([H])C([H])([H])N(C([H])([H])[H])[C@]3([H])C([H])([H])C1=C(O2)C([H])=C([H])C([H])=C1[H]
[H]OC1=C([H])C2=C3C(=C1[H])C([H])([H])C([H])([H])N([H])[C@]3([H])C([H])([H])C1=C(C([H])=C([H])C([H])=C1[H])C2([H])[H]
[H]C(=O)OC1=C([H])C([H])=C([H])C2=C1C1=C3C(=C([H])C(F)=C1[H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])[H])[C@]3([H])C2([H])[H]
[H]OC1=C([H])C2=C3C(=C1[H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])[H])[C@]3([H])C([H])([H])C1=C(O2)C([H])=C([H])C([H])=C1[H]
[H]OC1=C(OC([H])([H])[H])C(OC([H])([H])[H])=C2C3=C1C1=C(C([H])=C([H])C([H])=C1[H])C([H])([H])[C@@]3([H])N([H])C([H])([H])C2([H])[H]
[H]OC1=C([H])C([H])=C([H])C2=C1C1=C3C(=C([H])C4=C1OC([H])([H])O4)C([H])([H])C([H])([H])N(C([H])([H])[H])[C@@]3([H])C2([H])[H]
[H]C1=C([H])C2=C(C([H])=C1[H])C([H])([H])[C@]1([H])N(C([H])([H])[H])C([H])([H])C([H])([H])C3=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C(=C13)C2([H])[H]
[H]N1C([H])([H])C([H])([H])C2=C([H])C(OC([H])([H])[H])=C([H])C3=C2[C@@]1([H])C([H])([H])C1=C(C([H])=C([H])C([H])=C1[H])C3([H])[H]
[H]OC1=C([H])C2=C(OC3=C4C(=C([H])C([H])=C3O[H])C([H])([H])C([H])([H])N(C([H])([H])[H])[C@@]4([H])C2([H])[H])C([H])=C1OC([H])([H])[H]
[H]OC1=C(OC([H])([H])[H])C2=C3C(=C1[H])C([H])([H])C([H])([H])N(C([H])([H])[H])[C@@]3([H])C([H])([H])C1=C2C([H])=C(OC([H])([H])[H])C(OC([H])([H])[H])=C1[H]
[H]OC1=C([H])C2=C(C([H])=C1OC([H])([H])[H])C([H])([H])[C@]1([H])N(C([H])([H])[H])C([H])([H])C([H])([H])C3=C([H])C([H])=C(O[H])C(O2)=C13
[H]OC1=C(C([H])=C([H])C2=C1C1=C3C(=C([H])C([H])=C1[H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])[H])[C@]3([H])C2([H])[H])C([H])([H])O[H]
[H]OC1=C(C([H])=C([H])C2=C1C1=C3C(=C([H])C(OC([H])([H])[H])=C1[H])C([H])([H])C([H])([H])N(C([H])([H])[H])[C@]3([H])C2([H])[H])C([H])([H])[H]
[H]OC1=C(C([H])=C([H])C2=C1C1=C3C(=C([H])C([H])=C1[H])C([H])([H])C([H])([H])N(C([H])([H])[H])[C@]3([H])C2([H])[H])C([H])([H])O[H]
[H]OC1=C(C([H])=C([H])C2=C1C1=C3C(=C([H])C(OC([H])([H])[H])=C1[H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])[H])[C@]3([H])C2([H])[H])C([H])([H])[H]
[H]OC1=C([H])C2=C(OC3=C4C(=C([H])C([H])=C3[H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])[H])[C@@]4([H])C2([H])[H])C([H])=C1[H]
[H]OC1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C2=C3C(=C1[H])C([H])([H])C([H])([H])N(C([H])([H])[H])[C@]3([H])C([H])([H])C1=C2C(O[H])=C([H])C([H])=C1[H]
[H]C1=C2C(=C([H])C(OC([H])([H])[H])=C1OC([H])([H])[H])C([H])([H])[C@]1([H])N(C([H])([H])[H])C([H])([H])C([H])([H])C3=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C2=C13
[H]OC1=C([H])C2=C3C(=C1[H])C([H])([H])C([H])([H])N(C([H])([H])[H])[C@]3([H])C([H])([H])C1=C2C(OC([H])([H])C([H])([H])C([H])([H])[H])=C([H])C([H])=C1[H]
[H]OC1=C([H])C2=C3C(=C1[H])C([H])([H])C([H])([H])N(C([H])([H])[H])[C@]3([H])C([H])([H])C1=C2C(OC([H])([H])C([H])([H])[H])=C([H])C([H])=C1[H]
[H]C1=C([H])C2=C(C([H])=C1[H])C([H])([H])[C@@]1([H])N(C([H])([H])[H])C([H])([H])C([H])([H])C3=C([H])C(OC([H])([H])[H])=C([H])C2=C13
[H]C1=C([H])C([H])=C2N=C(SC([H])([H])C([H])([H])C([H])([H])N3C([H])([H])C([H])([H])N(C4=C(OC([H])([H])[H])C([H])=C([H])C([H])=C4[H])C([H])([H])C3([H])[H])SC2=C1[H]
[H]C1=C([H])C([H])=C2N=C(OC2=C1[H])SC([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C(OC([H])([H])[H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]C1=C([H])C([H])=C2N=C(OC2=C1[H])SC([H])([H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C(OC([H])([H])[H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]C1=C([H])C([H])=C2N=C(SC([H])([H])C([H])([H])C([H])([H])C([H])([H])N3C([H])([H])C([H])([H])N(C4=C(OC([H])([H])[H])C([H])=C([H])C([H])=C4[H])C([H])([H])C3([H])[H])SC2=C1[H]
[H]C1=C([H])C([H])=C([H])C(=N1)N1C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])SC2=NC3=C([H])C([H])=C([H])C([H])=C3S2)C([H])([H])C1([H])[H]
[H]C1=C2N(C3=C([H])C([H])=C([H])C([H])=C13)C([H])([H])C([H])([H])N(C2=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C(Cl)C(Cl)=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]C1=C2N(C3=C([H])C([H])=C([H])C([H])=C13)C([H])([H])C([H])([H])N(C2=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C(Cl)C([H])=C(Cl)C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N(C(=O)C1=C([H])C2=C([H])C([H])=C([H])C([H])=C2C([H])=N1)C([H])([H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C([H])C([H])=C([H])C(Cl)=C2Cl)C([H])([H])C1([H])[H]
[H]N(C(=O)C1=C([H])C2=C([H])C([H])=C([H])C([H])=C2C([H])=N1)C([H])([H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C([H])C([H])=C([H])C(Cl)=C2[H])C([H])([H])C1([H])[H]
[H]N([H])C1=NC2=C(S1)C([H])([H])[C@@]([H])(N(C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[C@@]1([H])C([H])([H])C([H])([H])[C@]([H])(N([H])C(=O)C3=C([H])C4=C(O3)C([H])=C([H])C([H])=C4[H])C([H])([H])C1([H])[H])C([H])([H])C2([H])[H]
[H]N([H])C1=NC2=C(S1)C([H])([H])[C@@]([H])(N(C([H])([H])C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C([H])([H])[C@@]1([H])C([H])([H])C([H])([H])[C@]([H])(N([H])C(=O)C3=C([H])C([H])=C4C([H])=C([H])C([H])=C([H])C4=C3[H])C([H])([H])C1([H])[H])C([H])([H])C2([H])[H]
[H]N1C(=O)C([H])([H])C([H])([H])C2=C1C([H])=C(OC([H])([H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C3=C([H])C([H])=C([H])C(Cl)=C3Cl)C([H])([H])C1([H])[H])C([H])=C2[H]
[H]C1=C([H])C([H])=C2C([H])=C(OC([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N3C([H])([H])C([H])([H])N(C4=C(Cl)C(Cl)=C([H])C([H])=C4[H])C([H])([H])C3([H])[H])N=C([H])C2=C1[H]
[H]N(C(=O)C1=C([H])C2=C([H])C([H])=C([H])C([H])=C2O1)C([H])([H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C([H])C(=C([H])C([H])=C2[H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]C1=C([H])C2=C(C(OC(=O)C([H])([H])[H])=C1[H])C1=C3C(=C([H])C(OC([H])([H])[H])=C1[H])C([H])([H])C([H])([H])N(C([H])([H])[H])[C@]3([H])C2([H])[H]
[H]C1=C([H])C2=C(C(OC(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])=C1[H])C1=C3C(=C([H])C(OC([H])([H])[H])=C1[H])C([H])([H])C([H])([H])N(C([H])([H])[H])[C@]3([H])C2([H])[H]
[H]OC1=C(Cl)C([H])=C2C(=C1[H])[C@]([H])(C([H])([H])C([H])=C([H])[H])C([H])([H])N(C([H])([H])[H])C([H])([H])C2([H])[H]
[H]OC1=C(Cl)C([H])=C2C(=C1[H])[C@]([H])(C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])N(C([H])([H])[H])C([H])([H])C2([H])[H]
[H]OC1=C(Cl)C([H])=C2C(=C1[H])[C@]([H])(C([H])([H])C#C[H])C([H])([H])N(C([H])([H])[H])C([H])([H])C2([H])[H]
[H]OC1=C(Cl)C([H])=C2C(=C1[H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C2([H])[H]
[H]OC1=C(Cl)C([H])=C2C(=C1[H])[C@@]([H])(C1=C([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])N(C([H])([H])[H])C([H])([H])C2([H])[H]
[H]OC1=C(Cl)C([H])=C2C(=C1[H])[C@]([H])(SC([H])([H])C([H])([H])[H])C([H])([H])N(C([H])([H])[H])C([H])([H])C2([H])[H]
[H]OC1=C(Cl)C([H])=C2C(=C1[H])[C@@]([H])(C1=C([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])N(C([H])([H])[H])C([H])([H])C2([H])[H]
[H]OC1=C(Cl)C([H])=C2C(=C1[H])[C@]([H])(C([H])([H])N(C([H])([H])[H])C([H])([H])C2([H])[H])C1([H])C([H])=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC1=C(Cl)C([H])=C2C(=C1[H])[C@]([H])(C([H])([H])N(C([H])([H])[H])C([H])([H])C2([H])[H])[C@@]1([H])C([H])=C([H])C([H])([H])C([H])([H])C1([H])[H]
[H]OC1=C(Cl)C([H])=C2C(=C1[H])[C@]([H])(C([H])([H])N(C([H])([H])[H])C([H])([H])C2([H])[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]OC1=C(Cl)C([H])=C2C(=C1[H])[C@]([H])(OC([H])([H])C([H])([H])[H])C([H])([H])N(C([H])([H])[H])C([H])([H])C2([H])[H]
[H]OC1=C(Cl)C([H])=C2C(=C1[H])[C@]([H])(C([H])([H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H])C([H])([H])N(C([H])([H])[H])C([H])([H])C2([H])[H]
[H]OC1=C(Cl)C([H])=C2C(=C1[H])[C@@]([H])(N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])N(C([H])([H])[H])C([H])([H])C2([H])[H]
[H]OC1=C(Cl)C([H])=C2C(=C1[H])C1(C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])N(C([H])([H])[H])C([H])([H])C2([H])[H]
[H]C1=C([H])C2=C([H])C([H])=C(C([H])=C2O1)C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[C@@]1([H])C2=C([H])C([H])=C([H])C(OC([H])([H])[H])=C2C([H])([H])C([H])([H])C1([H])[H]
[H]C1=C([H])C([H])=C([H])C(=N1)N1C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])[C@]2([H])C([H])([H])C([H])=C(C3=C([H])C([H])=C([H])C([H])=C3[H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]OC1=C(Cl)C([H])=C2C(=C1[H])[C@@]([H])(C1=C([H])C([H])=C([H])C(N=C=S)=C1[H])C([H])([H])N(C([H])([H])[H])C([H])([H])C2([H])[H]
[H]N(C(=O)C1=C([H])C(Cl)=C(N([H])C([H])([H])[H])C([H])=C1OC([H])([H])[H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(I)C([H])=C1[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])OC([H])(C2=C([H])C([H])=C(F)C([H])=C2[H])C2=C([H])C([H])=C(F)C([H])=C2[H])C([H])([H])C1([H])[H]
[H]C1=C([H])C2=C(C([H])=C1[H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1N2C([H])([H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H]
[H]\C(=C(\[H])[C@@]1([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]\C(=C(\[H])[C@@]1([H])C([H])([H])N(C([H])([H])C([H])=C(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC1=C([H])C2=C(C([H])=C1Cl)C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[C@]2([H])C1=C([H])C([H])=C([H])C2=C1OC([H])=C2[H]
[H]OC1=C(C([H])=C2C(=C1[H])[C@@]([H])(C1=C([H])C([H])=C([H])C3=C1OC([H])([H])C3([H])[H])C([H])([H])N(C([H])([H])[H])C([H])([H])C2([H])[H])[N+]([O-])=O
[H]OC1=C(Cl)C([H])=C2C(=C1[H])[C@@]([H])(C1=C([H])C([H])=C([H])C3=C1OC([H])([H])C3([H])[H])C([H])([H])N(C([H])([H])[H])C([H])([H])C2([H])[H]
[H]N(OC([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H])C(=C(/[H])C([H])=C1C([H])=C([H])C(=O)C([H])=C1[H])\C1=C([H])C([H])=C([H])C([H])=C1F
[H]\C(=C(\[H])[C@@]1([H])C([H])([H])N(C([H])([H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]\C(=C(/[H])[C@]1([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N([H])C1=NC(=NC2=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C([H])=C12)N1C([H])([H])C([H])([H])N(C(=O)C2=C([H])C([H])=C([H])O2)C([H])([H])C1([H])[H]
[H]N1C(=O)N(C([H])([H])C([H])([H])N2C([H])([H])C([H])([H])C([H])(C3=C([H])N(C4=C([H])C([H])=C(C([H])=C34)C3=NN(C([H])=N3)C([H])([H])[H])C3=C([H])C([H])=C(F)C([H])=C3[H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]C1=C(C2=C([H])C(=C([H])C([H])=C2N1C1=C([H])C([H])=C(F)C([H])=C1[H])C1=NN(N=N1)C([H])([H])[H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])N2C(=O)OC([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]OC1=C([H])C2=C(N([H])C([H])=C2C([H])([H])C([H])([H])N([H])[H])C([H])=C1[H]
[H]OC1=C(O[H])C([H])=C2C(=C1[H])C([H])([H])C([H])([H])[C@@]([H])(N([H])[H])C2([H])[H]
[H]N1C2=C(N=C3C([H])=C([H])C([H])=C([H])C3=C1N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H])C([H])=C([H])C(Cl)=C2[H]
[H]OC([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])N2C3=C(SC4=C2C([H])=C(C([H])=C4[H])C(F)(F)F)C([H])=C([H])C([H])=C3[H])C([H])([H])C1([H])[H]
[H]N1C([H])=C2C3=C(C([H])=C([H])C([H])=C13)[C@@]1([H])C([H])([H])[C@@]([H])(C([H])([H])SC([H])([H])[H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])[H])[C@]1([H])C2([H])[H]
[H]OC([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])N2C3=C([H])C([H])=C([H])C([H])=C3SC3=C2C([H])=C(Cl)C([H])=C3[H])C([H])([H])C1([H])[H]
[H]N1C(=O)N(C2=C([H])C([H])=C([H])C([H])=C12)C1([H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])C([H])(C2=C([H])C([H])=C(F)C([H])=C2[H])C2=C([H])C([H])=C(F)C([H])=C2[H])C([H])([H])C1([H])[H]
[H]C1=C([H])C2=C(C([H])=C1[H])N(C1=C([H])C([H])=C([H])C([H])=C1S2)C([H])([H])[C@@]([H])(N(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H]
[H]\C(=C1/C2=C([H])C([H])=C([H])C([H])=C2SC2=C1C([H])=C(C([H])=C2[H])S(=O)(=O)N(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N(\C(=N/C#N)C1=C([H])C([H])=NC([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C([H])C([H])=C([H])C(Cl)=C2[H])C([H])([H])C1([H])[H]
[H]N1C(=C([H])C2=C([H])C(OC([H])([H])C([H])([H])C([H])([H])N3C([H])([H])C([H])([H])N(C4=C([H])C(Cl)=C([H])C([H])=C4[H])C([H])([H])C3([H])[H])=C([H])C([H])=C12)C(=O)OC([H])([H])C([H])([H])[H]
[H]C1=NC(=C([H])C([H])=C1[H])N1C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N2C([H])([H])C([H])([H])N(C3=C([H])C([H])=C([H])C([H])=C3[H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])N1C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N2C([H])([H])C([H])([H])N(C3=C([H])C([H])=C([H])C(=N3)C([H])([H])[H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]C1=NC(=C([H])C([H])=C1[H])N1C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N2C([H])([H])C([H])([H])N(C3=C([H])C([H])=C([H])C([H])=N3)C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]C1=C([H])C(Cl)=C([H])C(=C1[H])N1C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N2C([H])([H])C([H])([H])N(C3=C([H])C([H])=C([H])C(Cl)=C3[H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]C1=C([H])C(OC([H])([H])[H])=C([H])C(=C1[H])N1C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N2C([H])([H])C([H])([H])N(C3=C([H])C([H])=C([H])C(OC([H])([H])[H])=C3[H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]C1=C([H])C(=C([H])C(=C1[H])N1C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N2C([H])([H])C([H])([H])N(C3=C([H])C([H])=C([H])C(=C3[H])C([H])([H])[H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H])C([H])([H])[H]
[H]C1=NC2=C([H])C([H])=C([H])C([H])=C2C(=C1[H])N1C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N2C([H])([H])C([H])([H])N(C3=C([H])C([H])=C([H])C([H])=C3[H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]C1=NC(=C([H])C([H])=C1[H])N1C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N2C([H])([H])C([H])([H])N(C3=C([H])C([H])=C([H])C(=C3[H])C([H])([H])[H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]C1=C([H])C(=NC(=C1[H])N1C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N2C([H])([H])C([H])([H])N(C3=C([H])C([H])=C([H])C(=C3[H])C([H])([H])[H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H])C([H])([H])[H]
[H]C1=C([H])C(Cl)=C([H])C(=C1[H])N1C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N2C([H])([H])C([H])([H])N(C3=C([H])C([H])=C([H])C(OC([H])([H])[H])=C3[H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])N1C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N2C([H])([H])C([H])([H])N(C3=C([H])C([H])=C([H])C([H])=C3[H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]OC1=C([H])C2=C(C([H])=C1OC([H])([H])[H])C([H])([H])C([H])([H])N(C([H])([H])[H])[C@@]2([H])C([H])([H])C1=C([H])C([H])=C(OC2=C([H])C(=C([H])C([H])=C2OC([H])([H])[H])C([H])([H])[C@@]2([H])N(C([H])([H])[H])C([H])([H])C([H])([H])C3=C2C([H])=C(O[H])C(OC([H])([H])[H])=C3[H])C([H])=C1[H]
[H]OC1=C([H])C([H])=C(C([H])=C1OC1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[C@]1([H])N(C([H])([H])[H])C([H])([H])C([H])([H])C2=C1C([H])=C(O[H])C(OC([H])([H])[H])=C2[H])C([H])([H])[C@@]1([H])N(C([H])([H])[H])C([H])([H])C([H])([H])C2=C1C([H])=C(O[H])C(OC([H])([H])[H])=C2[H]
CCCCN1CCC(COC(=O)C2=C3OCCOC3=C(NC)C(Cl)=C2)CC1
[H]OC1=C(Br)C([H])=C([H])C(OC([H])([H])[H])=C1C(=O)N([H])C([H])([H])[C@@]1([H])N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C1([H])[H]
[H]OC1=C(C(=O)N([H])C([H])([H])[C@@]2([H])N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C2([H])[H])C(OC([H])([H])[H])=C(Br)C([H])=C1Br
[H]OC1=C(C([H])=C([H])C(OC([H])([H])[H])=C1C(=O)N([H])C([H])([H])[C@@]1([H])N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C([H])([H])[H]
[H]OC1=C(C(=O)N([H])C([H])([H])[C@@]2([H])N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C2([H])[H])C(OC([H])([H])[H])=C(Br)C([H])=C1C([H])([H])C([H])([H])[H]
[H]OC1=C(C(=O)N([H])C([H])([H])[C@@]2([H])N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C2([H])[H])C(OC([H])([H])[H])=C(C([H])=C1C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H]
[H]OC1=C(C([H])=C(Cl)C(OC([H])([H])[H])=C1C(=O)N([H])C([H])([H])[C@@]1([H])N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C([H])([H])[H]
[H]N(C(=O)N1C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])C([H])(C2=C([H])C([H])=C(F)C([H])=C2[H])C2=C([H])C([H])=C(F)C([H])=C2[H])C([H])([H])C1([H])[H])C([H])([H])C([H])([H])[H]
[H]N1C2=C([H])C([H])=C([H])C([H])=C2N=C2SC(=C([H])C2=C1N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H])C([H])([H])[H]
[H]OC([H])([H])C([H])([H])OC([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=NC3=C([H])C([H])=C([H])C([H])=C3SC3=C2C([H])=C([H])C([H])=C3[H])C([H])([H])C1([H])[H]
[H]N1C(=O)N(C([H])([H])C([H])([H])N2C([H])([H])C([H])([H])C([H])(C3=C([H])N(C4=C([H])C([H])=C(Cl)C([H])=C34)C3=C([H])C([H])=C(F)C([H])=C3[H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]N1C(=O)C([H])([H])C2=C1C([H])=C(Cl)C(=C2[H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=NSC3=C2C([H])=C([H])C([H])=C3[H])C([H])([H])C1([H])[H]
[H]C1=C2C(ON=C2C2([H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])OC3=C([H])C([H])=C(C([H])=C3OC([H])([H])[H])C(=O)C([H])([H])[H])C([H])([H])C2([H])[H])=C([H])C(F)=C1[H]
[H]N(C(=O)C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])[C@]2([H])C3=C([H])C(C#N)=C([H])C([H])=C3OC([H])([H])[C@@]2([H])C1([H])[H]
[H]N1C([H])=C2C3=C(C(=C([H])C([H])=C13)C(=O)C([H])([H])[H])C([H])([H])[C@]([H])(N(C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[H])C2([H])[H]
[H]O[C@]1([H])C2=NC(=C(C(=O)N2C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])(C2=NOC3=C2C([H])=C([H])C(F)=C3[H])C([H])([H])C1([H])[H])C([H])([H])[H]
[H]N1C(=O)C2(N(C3=C([H])C([H])=C([H])C([H])=C3[H])C1([H])[H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])C([H])(C1=C([H])C([H])=C(F)C([H])=C1[H])C1=C([H])C([H])=C(F)C([H])=C1[H])C([H])([H])C2([H])[H]
[H]C1=C([H])C([H])=C2C(OC3=C(C([H])=C(Cl)C([H])=C3[H])[C@]3([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[C@@]23[H])=C1[H]
[H]OC([H])([H])C([H])([H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C(\[H])=C2\C3=C(SC4=C2C([H])=C(C([H])=C4[H])C(F)(F)F)C([H])=C(F)C([H])=C3[H])C([H])([H])C1([H])[H]
[H]N([H])C(=O)C1(N2C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])C(=O)C2=C([H])C([H])=C(F)C([H])=C2[H])C([H])([H])C1([H])[H]
[H]C1=C([H])C([H])=C2C([H])=C(OC([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H])C3=C(SC2=C1[H])C([H])=C([H])C(Cl)=C3[H]
[H]N([H])S(=O)(=O)C1=C([H])C([H])=C(C([H])=C1[H])N1C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])[C@@]2([H])OC([H])([H])C([H])([H])C3=C([H])C([H])=C([H])C([H])=C23)C([H])([H])C1([H])[H]
[H]N(C([H])([H])[H])C([H])([H])C([H])([H])[C@]([H])(OC1=C([H])C([H])=C([H])C2=C([H])C([H])=C([H])C([H])=C12)C1=C([H])C([H])=C([H])S1
[H]OC1(C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])[C@@]([H])(C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H]
[H]N([H])C(=O)C1=C2C(OC([H])([H])[C@@]([H])(N(C3([H])C([H])([H])C([H])([H])C3([H])[H])C3([H])C([H])([H])C([H])([H])C3([H])[H])C2([H])[H])=C(F)C([H])=C1[H]
[H]C1=C([H])C([H])=C([H])C(=N1)N(C(=O)C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C(OC([H])([H])[H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
CN1CCc2c(Cl)c(O)c(O)cc2[C@H](C1)c1cccc(C)c1
CN1CCc2c(Br)c(O)c(O)cc2[C@@H](C1)c1cccc(C)c1
Cc1cccc(c1)C1CN(CC=C)CCc2c(Br)c(O)c(O)cc12
CN1CCc2c(Cl)c(O)c(O)cc2C(C1)c1ccc(C)cc1
CN1CCc2c(Cl)c(O)c(O)cc2C(C1)c1ccccc1C
Cc1cccc(c1)C1CN(CC=C)CCc2c(Cl)c(O)c(O)cc12
CN1CCc2c(cc(O)c(O)c2Br)[C@@H](C1)c1cccc(c1)C(F)(F)F
CN1CCc2c(Br)c(O)c(O)cc2C(C1)c1ccc(C)cc1
Cc1ccc(cc1)C1CN(CC=C)CCc2c(Br)c(O)c(O)cc12
CN1CCc2c(Br)c(O)c(O)cc2C(C1)c1ccccc1C
Cc1ccccc1C1CN(CC=C)CCc2c(Br)c(O)c(O)cc12
[H]OC1=C(O[H])C(Cl)=C2C(=C1[H])[C@@]([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])N([H])C([H])([H])C2([H])[H]
[H]OC1=C([H])C2=C(C(Cl)=C1O[H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[C@@]2([H])C1=C([H])C([H])=C([H])C(=C1[H])C([H])([H])[H]
[H][C@]12CNCc3cccc(Cc4c(O)c(O)cc(Cl)c14)c23
[H][C@]12CN(C)C(C)c3cccc(Cc4c(O)c(O)ccc14)c23
[H][C@]12CN(C)Cc3cccc(Cc4c(O)c(O)ccc14)c23
[H][C@]12CN(CCC)Cc3cccc(Cc4c(O)c(O)ccc14)c23
[H][C@]12CNC(CCCC)c3cccc(Cc4c(O)c(O)ccc14)c23
[H][C@]12CNC(c3cccc(Cc4c(O)c(O)ccc14)c23)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F
[H][C@]12CNCc3cccc(C(CC)c4c(O)c(O)ccc14)c23
[H][C@]12CNCc3cccc(C(CC(=O)OC)c4c(O)c(O)ccc14)c23
Oc1ccc2C3CNCc4ccc(F)c(Cc2c1O)c34
Oc1ccc2C3CNCc4cccc(Sc2c1O)c34
[H][C@]12CNCc3c(F)ccc(Cc4c(O)c(O)ccc14)c23
[H][C@]12CNCc3c(O)ccc(Cc4c(O)c(O)ccc14)c23
[H][C@]12CNCc3ccc(CC)c(Cc4c(O)c(O)ccc14)c23
[H]OC1=C([H])C2=C(C([H])=C1O[H])[C@]1([H])C3=C(C(=C([H])C([H])=C3[H])C([H])([H])[H])C([H])([H])N([H])[C@@]1([H])C([H])([H])C2([H])[H]
[H]OC1=C([H])C2=C(C([H])=C1O[H])[C@]1([H])C3=C(C(=C([H])C([H])=C3[H])C([H])([H])[H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])[H])[C@@]1([H])C([H])([H])C2([H])[H]
[H][C@]12CNCc3c(C)ccc(Cc4c(O)c(O)ccc14)c23
[H][C@]12CN(CC=C)Cc3c(C)ccc(Cc4c(O)c(O)ccc14)c23
[H][C@]12CN(CCC)Cc3c(C)ccc(Cc4c(O)c(O)ccc14)c23
[H][C@]12CNCc3ccc(C)c(Cc4c(O)c(O)ccc14)c23
[H][C@]12CN(CC=C)Cc3cccc(Cc4c(O)c(O)ccc14)c23
[H]C1=C([H])C(=C([H])C([H])=C1F)C1=C([H])C(=NC2=C1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])N1C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]OC([H])([H])[C@@]([H])(N([H])C(=O)[C@]1([H])C([H])=C2C3=C([H])C([H])=C([H])C4=C3C(=C([H])N4C([H])([H])[H])C([H])([H])[C@@]2([H])N(C([H])([H])[H])C1([H])[H])C([H])([H])C([H])([H])[H]
[H]OC1=C([H])C([H])=C([H])C2=C1C1=C([H])C(OC([H])([H])[H])=C([H])C3=C1[C@@]([H])(N(C([H])([H])C([H])([H])[H])C([H])([H])C3([H])[H])C2([H])[H]
[H]OC1=C([H])C([H])=C([H])C2=C1C1=C([H])C(OC([H])([H])[H])=C([H])C3=C1[C@@]([H])(N(C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C3([H])[H])C2([H])[H]
[H]OC(=O)C1=C([H])C([H])=C([H])C([H])=C1C(=O)N([H])C1=C([H])C([H])=C([H])C2=C([H])C([H])=C([H])C([H])=C12
[H]N(C([H])([H])[H])C([H])([H])C([H])([H])[C@]([H])(OC1=C(C([H])=C([H])C([H])=C1[H])C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C(=C1C2=C([H])C([H])=C([H])C([H])=C2C([H])([H])C([H])([H])C2=C1C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])C([H])=C2C(=C1[H])N(C1=C([H])C([H])=C([H])C([H])=C1C([H])([H])C2([H])[H])C([H])([H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C(=O)C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]C1=C([H])C([H])=C(OC([H])([H])C([H])([H])N2C(=O)N(N=C2C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])N2C([H])([H])C([H])([H])N(C3=C([H])C(Cl)=C([H])C([H])=C3[H])C([H])([H])C2([H])[H])C([H])=C1[H]
[H]N(C([H])([H])[H])[C@@]1([H])C2=C([H])C([H])=C([H])C([H])=C2[C@]([H])(C2=C([H])C(Cl)=C(Cl)C([H])=C2[H])C([H])([H])C1([H])[H]
[H]OC1=C(C(=C(C([H])=C1[H])N1C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])C([H])([H])OC2=C([H])C3=C(C([H])=C2[H])C([H])([H])C([H])([H])C(=O)N3[H])C([H])([H])C1([H])[H])C([H])([H])[H])C([H])([H])[H]
[H]OC1=C([H])C2=C(C([H])=C1O[H])C([H])([H])C([H])([H])N([H])C([H])([H])C2([H])[H]
[H]OC1=C([H])C([H])=C2C(C3=C(C([H])=C([H])C([H])=C3[H])[C@]2([H])C([H])([H])N([H])[H])=C1O[H]
[H]OC1=C(Cl)C([H])=C2C(=C1[H])[C@]([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])N([H])C([H])([H])C2([H])[H]
[H]OC1=C([H])C([H])=C(C(=C1O[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])N([H])[H]
[H]OC1=C([H])C([H])=C(C(C2=C([H])C([H])=C([H])C([H])=C2[H])=C1O[H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]OC1=C(O[H])C([H])=C2C(=C1[H])C([H])([H])C([H])([H])[C@]([H])(C2([H])[H])[N+]([H])(C([H])([H])[H])C([H])([H])[H]
[H]OC1=C(Cl)C2=C(C(=C1O[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])N([H])C([H])([H])C2([H])[H]
[H]OC1=C([H])C([H])=C(C([H])=C1[H])C1=C(O[H])C(O[H])=C(Cl)C2=C1C([H])([H])C([H])([H])N([H])C([H])([H])C2([H])[H]
[H]OC1=C([H])C2=C(C(=C1O[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])N([H])C([H])([H])C2([H])[H]
[H]OC1=C([H])C([H])=C(C([H])=C1[H])C1=C(O[H])C(O[H])=C([H])C([H])=C1C([H])([H])C([H])([H])N([H])[H]
[H]OC1=C([H])C([H])=C(C([H])=C1[H])C1=C(O[H])C(O[H])=C([H])C([H])=C1C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]OC1=C([H])C([H])=C(C([H])=C1[H])C1=C(O[H])C(O[H])=C([H])C2=C1C([H])([H])C([H])([H])N([H])C([H])([H])C2([H])[H]
[H]OC1=C([H])C2=C(C([H])=C1[H])C1=C(O[H])C(O[H])=C([H])C([H])=C1[C@@]2([H])C([H])([H])N([H])[H]
[H]OC1=C([H])C([H])=C(C([H])=C1[H])[C@]1([H])C2=C([H])C(O[H])=C(O[H])C([H])=C2C([H])([H])C([H])([H])N(C([H])([H])C([H])=C([H])[H])C1([H])[H]
[H]OC1=C([H])C([H])=C(C([H])=C1[H])[C@]1([H])C2=C([H])C(O[H])=C(O[H])C(F)=C2C([H])([H])C([H])([H])N(C([H])([H])C([H])=C([H])[H])C1([H])[H]
[H]OC1=C([H])C([H])=C(C([H])=C1[H])[C@]1([H])C2=C([H])C(O[H])=C(O[H])C(Cl)=C2C([H])([H])C([H])([H])N(C([H])([H])C([H])=C([H])[H])C1([H])[H]
[H]OC1=C([H])C([H])=C(C([H])=C1[H])[C@]1([H])C2=C([H])C(O[H])=C(O[H])C(=C2C([H])([H])C([H])([H])N(C([H])([H])C([H])=C([H])[H])C1([H])[H])C([H])([H])[H]
[H]OC1=C([H])C([H])=C(C([H])=C1[H])[C@]1([H])C2=C([H])C(O[H])=C(O[H])C(Br)=C2C([H])([H])C([H])([H])N(C([H])([H])C([H])=C([H])[H])C1([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])[C@]1(OC(=O)C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])C(=O)C2=C([H])C([H])=C(F)C([H])=C2[H])C([H])([H])[C@@]1([H])C([H])([H])[H]
[H]OC1(C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])C(=O)C2=C([H])C([H])=C(F)C([H])=C2[H])C([H])([H])C1([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])C(=O)C2=C([H])C([H])=C(F)C([H])=C2[H])C([H])([H])C1([H])[H]
[H]OC1=C([H])C([H])=C(C([H])=C1O[H])[C@@]1([H])C2=C([H])C([H])=C([H])C([H])=C2[C@]2([H])N(C([H])([H])C([H])([H])C2([H])[H])C1([H])[H]
[H]OC1=C(O[H])C([H])=C2C(=C1[H])[C@]1([H])N(C([H])([H])C([H])([H])C1([H])[H])C([H])([H])[C@@]2([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C1=C([H])C(=C([H])C([H])=C1F)[C@@]1([H])C2=C([H])C([H])=C(F)C([H])=C2[C@]2([H])N(C([H])([H])C([H])([H])C2([H])[H])C1([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])[C@@]1([H])C2=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C([H])=C2[C@@]2([H])N(C([H])([H])C([H])([H])C2([H])[H])C1([H])[H]
[H]OC1=C(Cl)C([H])=C2C(=C1[H])[C@]([H])(C1=C([H])C([H])=C([H])C([H])=C1Br)C([H])([H])N(C([H])([H])[H])C([H])([H])C2([H])[H]
CN1CCC2=CC(Cl)=C(O)C=C2C(C1)C1=CC=CC=C1C(=O)C1=CC=C[C@@H]1[Re](C=O)(C=O)C=O
[H]OC1=C(Cl)C([H])=C2C(=C1[H])[C@@]([H])(C1=C([H])C([H])=C([H])C(Br)=C1[H])C([H])([H])N(C([H])([H])[H])C([H])([H])C2([H])[H]
CN1CCC2=CC(Cl)=C(O)C=C2C(C1)C1=CC=CC(=C1)C(=O)C1=CC=C[C@@H]1[Re](C=O)(C=O)C=O
[H]OC([H])([H])C1=C([H])C([H])=C2SC3=C([H])C([H])=C([H])C([H])=C3C(=C([H])N12)N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H]
[H]C1=C([H])N2C([H])=C(N3C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C3([H])[H])C3=C([H])C(Br)=C([H])C([H])=C3SC2=C1[H]
[H]C1=C([H])N2C([H])=C(N3C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C3([H])[H])C3=C([H])C(F)=C([H])C([H])=C3SC2=C1[H]
[H]N1C(=O)N(C([H])([H])C([H])([H])N2C([H])([H])C([H])([H])N(C([H])([H])C2([H])[H])[C@@]2([H])C3=C([H])C(Cl)=C([H])C([H])=C3SC3=C([H])C([H])=C([H])N3C2([H])[H])C([H])([H])C1([H])[H]
[H]C1=C2SC3=C([H])C([H])=C([H])C([H])=C3C(=C([H])N2C(=C1[H])C([H])([H])[H])N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H]
[H]C1=C([H])N2C([H])=C(N3C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C3([H])[H])C3=C([H])C(Cl)=C([H])C([H])=C3SC2=C1[H]
[H]C(=O)C1=C([H])C([H])=C2SC3=C([H])C([H])=C([H])C([H])=C3C(=C([H])N12)N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N(\C(=N/C#N)C1=NC([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C([H])C([H])=C([H])C([H])=C2OC([H])([H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N(\C(=N/C#N)C1=NC([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=C([H])C([H])=C([H])C(Cl)=C2[H])C([H])([H])C1([H])[H]
[H]C1=C([H])N2C([H])=C(N3C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C([H])([H])C3([H])[H])C3=C([H])C(Cl)=C([H])C([H])=C3SC2=C1[H]
[H]C1=C2SC3=C([H])C([H])=C([H])C([H])=C3C(=C([H])N2C(=C1[H])C([H])([H])OC([H])(C([H])([H])[H])C([H])([H])[H])N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N1C(=O)N(C([H])([H])C([H])([H])N2C([H])([H])C([H])([H])C([H])(C3=C([H])N(C4=C([H])C([H])=C(C([H])=C34)C3=NN(N=N3)C([H])([H])[H])C3=C([H])C([H])=C(F)C([H])=C3[H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]C1=NC(=NN1C([H])([H])[H])C1=C([H])C([H])=C2N(C([H])=C(C2=C1[H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])[C@@]2([H])C(=O)N(C([H])([H])[H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]N1C(=O)N(C(=O)C2=C1C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])(C2=C([H])N(C3=C([H])C([H])=C(C([H])=C23)C2=NN(C([H])=N2)C([H])([H])[H])C2=C([H])C([H])=C(F)C([H])=C2[H])C([H])([H])C1([H])[H]
[H]C1=C(C2=C([H])C(=C([H])C([H])=C2N1C1=C([H])C([H])=C(F)C([H])=C1[H])C1=NC([H])=C([H])C([H])=N1)C1([H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C#N)C([H])([H])C1([H])[H]
[H]C1=NC(=NN1C([H])([H])[H])C1=C([H])C([H])=C2N(C([H])=C(C2=C1[H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])N2C(=O)OC([H])([H])C2([H])[H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]O[C@@]([H])(C#CC#C[C@@]([H])(O[H])C(\[H])=C(\[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])=C([H])[H]
[H]O[C@]([H])(C([H])=C(C([H])([H])[H])C([H])([H])[H])C([H])([H])C(=C(/[H])C([H])([H])OC1=C2C([H])=C([H])C(=O)OC2=C([H])C2=C1C([H])=C([H])O2)\C([H])([H])[H]
[H]N(C(=O)N(C([H])([H])[H])C([H])([H])[H])[C@@]1([H])C([H])([H])C([H])([H])[C@]([H])(C([H])([H])C([H])([H])N2C([H])([H])C([H])([H])N(C3=C([H])C([H])=C([H])C(Cl)=C3Cl)C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]