[H]C#CC([H])([H])N([H])[C@@]1([H])C2=C([H])C([H])=C([H])C(OC(=O)N(C([H])([H])[H])C([H])([H])C([H])([H])[H])=C2C([H])([H])C1([H])[H] [H]C#CC([H])([H])N([H])[C@@]1([H])C2=C([H])C([H])=C([H])C([H])=C2C([H])([H])C1([H])[H] [H]OC1=C([H])C([H])=C2C(=C1[H])[C@]([H])(N([H])C([H])([H])C#C[H])C([H])([H])C2([H])[H] [H]C#CC([H])([H])N(C([H])([H])[H])[C@@]1([H])C2=C([H])C([H])=C([H])C([H])=C2C([H])([H])C1([H])[H] [H]C#CC([H])([H])N(C([H])([H])[H])[C@@]1([H])C2=C([H])C([H])=C([H])C(OC(=O)N(C([H])([H])[H])C([H])([H])C([H])([H])[H])=C2C([H])([H])C1([H])[H] [H]OC1=C2C(=C([H])C([H])=C1[H])[C@]([H])(N([H])C([H])([H])C#C[H])C([H])([H])C2([H])[H] [H]OC(=O)C1=C([H])C([H])=C(N([H])C(=O)C2=C([H])C3=C(OC2=O)C([H])=C([H])C([H])=C3[H])C([H])=C1[H] [H]N(C(=O)C1=C([H])C2=C(OC1=O)C([H])=C([H])C([H])=C2[H])C1=C([H])C([H])=C(C([H])=C1[H])C(Cl)=O [H]N(C(=O)C1=C([H])C2=C(OC1=O)C([H])=C([H])C([H])=C2[H])C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)C([H])([H])[H] [H]OC1=C([H])C([H])=C(C(=O)C(\[H])=C(/[H])C2=C([H])C([H])=C(Cl)C([H])=C2[H])C(O[H])=C1[H] [H]N(C(=O)C1=C([H])C2=C(OC1=O)C([H])=C([H])C([H])=C2[H])C1=C(C([H])=C([H])C([H])=C1C([H])([H])[H])C([H])([H])[H] [H]N(C(=O)C1=C([H])C2=C(OC1=O)C([H])=C([H])C([H])=C2[H])C1=C([H])C([H])=C(OC([H])([H])[H])C(OC([H])([H])[H])=C1[H] [H]C#CC([H])([H])N(C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])OC1=C(Cl)C([H])=C(Cl)C([H])=C1[H] [H]N(N([H])C([H])(C([H])([H])[H])C([H])([H])[H])C(=O)C1=C([H])C([H])=NC([H])=C1[H] [H]C1=C([H])C([H])=C2C(OC3=C(C(=C([H])C([H])=C3[H])C([H])([H])C([H])([H])[H])S2(=O)=O)=C1[H] [H]\C(=C(\[H])C1=C([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H] [H]OC1=C([H])C([H])=C2OC3=C(C(=O)C2=C1[H])C(O[H])=C([H])C(O[H])=C3[H] [H]OC1=C([H])C2=C(C([H])=C1[H])C(=O)C1=C(O2)C([H])=C([H])C([H])=C1[H] [H]OC1=C([H])C2=C(OC3=C(C([H])=C([H])C([H])=C3[H])C2=O)C([H])=C1[H] [H]C1=C([H])C2=C(C([H])=C1[H])C(=O)C1=C([H])C([H])=C([H])C([H])=C1O2 [H]OC1=C([H])C2=C(C(=O)C3=C(O2)C([H])=C([H])C([H])=C3[H])C(O[H])=C1C([H])([H])[H] [H]C1=C([H])C2=C(C([H])=C1[H])C(=O)C1=C(O2)C([H])=C([H])C([H])=C1OC([H])([H])[H] [H]OC1=C([H])C([H])=C([H])C2=C1OC1=C(C([H])=C([H])C([H])=C1[H])C2=O [H]OC1=C([H])C([H])=C([H])C2=C1C(=O)C1=C([H])C([H])=C([H])C([H])=C1O2 [H]C1=C([H])C2=C(C([H])=C1[H])C(=O)C1=C(O2)C([H])=C([H])C(OC([H])([H])[H])=C1[H] [H]OC1=C([H])C([H])=C([H])C2=C1OC1=C(C2=O)C(O[H])=C([H])C([H])=C1[H] [H]OC1=C([H])C([H])=C(O[H])C2=C1OC1=C([H])C(OC([H])([H])[H])=C([H])C(O[H])=C1C2=O [H]OC1=C([H])C([H])=C([H])C2=C1OC1=C(C(O[H])=C([H])C(OC([H])([H])[H])=C1[H])C2=O [H]OC1=C([H])C([H])=C([H])C2=C1OC1=C(C2=O)C(O[H])=C(OC([H])([H])[H])C(O[H])=C1[H] [H]OC1=C([H])C2=C(C([H])=C1[H])C(=O)C1=C(O2)C(O[H])=C([H])C([H])=C1[H] [H]OC1=C([H])C2=C(C(=O)C3=C(O2)C(O[H])=C([H])C([H])=C3[H])C(O[H])=C1[H] [H]OC1=C(O[H])C2=C(OC3=C([H])C(OC([H])([H])[H])=C([H])C(O[H])=C3C2=O)C([H])=C1[H] [H]OC1=C([H])C([H])=C([H])C2=C1OC1=C(C2=O)C(O[H])=C(C([H])=C1O[H])C([H])([H])C([H])=C(C([H])([H])[H])C([H])([H])[H] [H]OC1=C([H])C(O[H])=C(C2=C1C(=O)C1=C(O2)C([H])=C([H])C([H])=C1[H])C([H])([H])[H] [H]C1=C([H])C2=C(C([H])=C1[H])C(=O)C1=C(O2)C([H])=C(OC([H])([H])[H])C([H])=C1[H] [H]OC1=C([H])C(OC([H])([H])[H])=C([H])C2=C1C(=O)C1=C([H])C([H])=C([H])C([H])=C1O2 [H]N([H])N([H])C(=O)N([H])[H] [H]N(C(=O)C([H])([H])[H])C([H])([H])[C@]1([H])OC(=O)N(C2=C([H])C(F)=C(C([H])=C2[H])C2=C([H])C([H])([H])S(=O)(=O)C([H])([H])C2([H])[H])C1([H])[H] [H]C1=C(N(N=N1)C([H])([H])[C@]1([H])OC(=O)N(C2=C([H])C([H])=C(C(F)=C2[H])C2=C([H])C([H])([H])S(=O)(=O)C([H])([H])C2([H])[H])C1([H])[H])C([H])([H])[H] [H]C1=C(F)N=NN1C([H])([H])[C@]1([H])OC(=O)N(C2=C([H])C([H])=C(C(F)=C2[H])C2=C([H])C([H])([H])S(=O)(=O)C([H])([H])C2([H])[H])C1([H])[H] [H]C1=C(Cl)N=NN1C([H])([H])[C@]1([H])OC(=O)N(C2=C([H])C([H])=C(C(F)=C2[H])C2=C([H])C([H])([H])S(=O)(=O)C([H])([H])C2([H])[H])C1([H])[H] [H]C1=C([H])N(N=N1)C([H])([H])[C@]1([H])OC(=O)N(C2=C([H])C([H])=C(C(F)=C2[H])C2=C([H])C([H])([H])S(=O)(=O)C([H])([H])C2([H])[H])C1([H])[H] [H]C1=C(F)N(N=N1)C([H])([H])[C@]1([H])OC(=O)N(C2=C([H])C([H])=C(C(F)=C2[H])C2=C([H])C([H])([H])S(=O)(=O)C([H])([H])C2([H])[H])C1([H])[H] [H]C1=C(N=NN1C([H])([H])[C@]1([H])OC(=O)N(C2=C([H])C([H])=C(C(F)=C2[H])C2=C([H])C([H])([H])S(=O)(=O)C([H])([H])C2([H])[H])C1([H])[H])C(=O)OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H] [H]C(=O)C1=C([H])N(N=N1)C([H])([H])[C@]1([H])OC(=O)N(C2=C([H])C([H])=C(C(F)=C2[H])C2=C([H])C([H])([H])S(=O)(=O)C([H])([H])C2([H])[H])C1([H])[H] [H]N([H])N([H])C([H])([H])C(=C(/[H])F)\C1=C([H])C([H])=C([H])C([H])=C1[H] [H]N([H])N([H])C([H])([H])C(=C([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H] [H]N([H])N([H])C([H])([H])C(=C([H])[H])C1=C([H])C([H])=C(Cl)C([H])=C1[H] [H]N([H])N([H])C([H])([H])C(=C([H])[H])C1=C([H])C([H])=C(F)C([H])=C1[H] [H]N([H])N([H])C([H])([H])C(=C([H])[H])C1=C(C([H])=C([H])C([H])=C1[H])C([H])([H])[H] [H]C1=C([H])C2=C(C([H])=C1[H])C1=C(O2)C([H])=C2OC(=O)C([H])=C(C2=C1[H])C([H])([H])[H] [H]N(C(=O)C([H])([H])[H])C1=C([H])C2=C([H])C([H])=C(OC([H])([H])C(=O)C([H])([H])[H])C(OC([H])([H])[H])=C2OC1=O [H]N([H])C([H])([H])C([H])([H])C([H])([H])OC1=C2OC(=O)C([H])=C([H])C2=C([H])C2=C1OC([H])=C2[H] [H]C1=C(O[C@@]2([H])C(=O)C([H])([H])C([H])([H])C2([H])[H])C([H])=C2OC(=O)C([H])=C(C2=C1[H])C([H])([H])[H] [H]C1=C([H])C(=C([H])C(=C1[H])C1=C([H])C2=C(N=N1)C1=C(C([H])=C(OC([H])([H])[H])C([H])=C1[H])C2=O)C(F)(F)F [H]C1=C([H])C(=C([H])C(=C1[H])C1=C([H])C2=C(N=N1)C1=C(C([H])=C([H])C(OC([H])([H])[H])=C1[H])C2=O)C(F)(F)F [H]C1=C([H])N(N=N1)C([H])([H])[C@]1([H])OC(=O)N(C2=C([H])C([H])=C(C(F)=C2[H])C2=C([H])N=C(C([H])=C2[H])C(=O)C([H])([H])N2C([H])=NC(=C2[H])C([H])([H])[H])C1([H])[H] [H]OC([H])([H])C1=NC([H])=C(C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1F)N1C(=O)O[C@@]([H])(C([H])([H])N2N=NC([H])=C2[H])C1([H])[H] [H]N([H])[C@@]([H])(C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(SC([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])=C1[H] [H]N([H])[C@@]([H])(C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(SC([H])([H])[H])C([H])=C1[H] [H]N([H])[C@@]([H])(C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(SC([H])([H])C([H])([H])[H])C([H])=C1[H] [H]N([H])[C@@]([H])(C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(SC([H])([H])C([H])([H])C([H])([H])[H])C([H])=C1[H] [H]O[C@@]([H])(C1=NC([H])=C(C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1F)N1C(=O)O[C@@]([H])(C([H])([H])N2N=NC([H])=C2[H])C1([H])[H])C([H])([H])[H] [H]C1=C([H])N(N=N1)C([H])([H])[C@]1([H])OC(=O)N(C2=C([H])C([H])=C(C(F)=C2[H])C2=C([H])N=C(C([H])=C2[H])[C@]([H])(OC([H])([H])[H])C([H])([H])[H])C1([H])[H] [H]C1=C([H])N(N=N1)C([H])([H])[C@]1([H])OC(=O)N(C2=C([H])C([H])=C(C(F)=C2[H])C2=C([H])N=C(C([H])=C2[H])C([H])([H])OC([H])([H])[H])C1([H])[H] [H]N1C([H])([H])C([H])(C(=O)C2=NC([H])=C(C([H])=C2[H])C2=C([H])C([H])=C(C([H])=C2F)N2C(=O)O[C@@]([H])(C([H])([H])N3N=NC([H])=C3[H])C2([H])[H])C1([H])[H] [H]C1=C([H])N(N=N1)C([H])([H])[C@]1([H])OC(=O)N(C2=C([H])C([H])=C(C(F)=C2[H])C2=C([H])N=C(C([H])=C2[H])C(=O)C([H])([H])[H])C1([H])[H] [H]OC(C1=NC([H])=C(C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1F)N1C(=O)O[C@@]([H])(C([H])([H])N2N=NC([H])=C2[H])C1([H])[H])(C([H])([H])[H])C([H])([H])[H] [H]OC1=C2N=C([H])C([H])=C(C2=C([H])C([H])=C1[H])C([H])([H])N(C([H])([H])[H])C([H])([H])C#C[H] [H]C1=C([H])C(Cl)=C([H])C(=C1[H])C([H])([H])OC1=C([H])C2=C(C([H])=C1[H])C(=C(C(=O)O2)C([H])([H])[H])C([H])([H])[H] [H]C1=C2N(C3=C(C2=C(Br)C(OC(=O)N(C([H])([H])[H])C([H])([H])[H])=C1[H])C([H])([H])C([H])([H])\C3=N\C([H])([H])[H])C([H])([H])[H] [H]OC1=C2N=C([H])C([H])=C(C2=C([H])C([H])=C1[H])C([H])([H])N([H])C([H])([H])C#C[H] [H]N(\N=C1\C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C([H])([H])[H])C1=NC(=C([H])S1)C1=C([H])C([H])=C(C#N)C([H])=C1[H] [H]N(\N=C1\C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C([H])([H])[H])C1=NC(=C([H])S1)C1=C(F)C([H])=C(F)C([H])=C1[H] [H]N(\N=C1\C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C([H])([H])[H])C1=NC(=C([H])S1)C1=C([H])C([H])=C(F)C([H])=C1[H] [H]N(\N=C1\C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C([H])([H])[H])C1=NC(=C([H])S1)C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H] [H]N([H])C([H])([H])C(=C(/[H])F)\C([H])([H])C([H])([H])C1=C([H])C([H])=C(F)C([H])=C1[H] [H]C([H])=C(Br)C([H])([H])OC1=C([H])C([H])=C2C3=C(C(=O)OC2=C1C([H])([H])[H])C([H])([H])C([H])([H])C3([H])[H] [H]C1=C(OC([H])([H])C(=O)C([H])([H])[H])C(OC([H])([H])[H])=C2OC(=O)C3=C(C2=C1[H])C([H])([H])C([H])([H])C([H])([H])C3([H])[H] [H]C1=C(OC([H])([H])C(=O)C([H])([H])[H])C(=C2OC(=O)C3=C(C2=C1[H])C([H])([H])C([H])([H])C([H])([H])C3([H])[H])C([H])([H])[H] [H]C1=C(OC([H])([H])C(=O)C([H])([H])[H])C(=C2OC(=O)C3=C(C2=C1[H])C([H])([H])C([H])([H])C3([H])[H])C([H])([H])[H] [H]C1=C(OC([H])([H])C(=O)C([H])([H])[H])C(OC([H])([H])[H])=C2OC(=O)C3=C(C2=C1[H])C([H])([H])C([H])([H])C3([H])[H] [H]C1=C(O[C@@]2([H])C(=O)C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C(=C2OC(=O)C([H])=C(C2=C1[H])C([H])([H])[H])C([H])([H])[H] [H]C1=C(O[C@@]2([H])C(=O)C([H])([H])C([H])([H])C2([H])[H])C(=C2OC(=O)C([H])=C(C2=C1[H])C([H])([H])[H])C([H])([H])[H] [H]C1=C([H])C2=C([H])C([H])=C(O[C@@]3([H])C(=O)C([H])([H])C([H])([H])C3([H])[H])C(OC([H])([H])[H])=C2OC1=O [H]C([H])=C(Br)C([H])([H])OC1=C([H])C([H])=C2C(OC(=O)C3=C2C([H])=C([H])C([H])=C3[H])=C1C([H])([H])[H] [H]C1=C([H])C2=C(C([H])=C1[H])C1=C([H])C([H])=C(OC([H])([H])C(=O)C([H])([H])[H])C(=C1OC2=O)C([H])([H])[H] [H]C([H])=C(Br)C([H])([H])OC1=C([H])C([H])=C2C(OC(=O)C3=C2C([H])([H])C([H])([H])C([H])([H])C3([H])[H])=C1C([H])([H])[H] [H]N1C(=O)C(=O)C2=C1C([H])=C([H])C(\C([H])=C(/[H])C1=C([H])C([H])=C([H])C([H])=C1[H])=C2[H] [H]N1C(=O)C(=O)C2=C1C([H])=C([H])C(\C([H])=C(/[H])C1=C([H])C(Cl)=C([H])C([H])=C1[H])=C2[H] [H]N1C(=O)C(=O)C2=C1C([H])=C([H])C(\C([H])=C(/[H])C1=C([H])C(F)=C([H])C([H])=C1[H])=C2[H] [H]N1C(=O)C(=O)C2=C1C([H])=C(\C([H])=C(/[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])=C2[H] [H]N(C(=O)OC1=C([H])C([H])=C2N(C3=C(C2=C1Br)C([H])([H])C([H])([H])\C3=N\C([H])([H])[H])C([H])([H])[H])C([H])([H])[H] [H]C1=C([H])C([H])=C2C(=C1[H])N(C1=C2C([H])([H])C([H])([H])\C1=N\C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])[H] [H]N(C(=O)OC1=C([H])C([H])=C2N(C3=C(C2=C1Cl)C([H])([H])C([H])([H])\C3=N\C([H])([H])[H])C([H])([H])[H])C([H])([H])[H] [H]N(C(=O)OC1=C([H])C([H])=C2N(C3=C(C2=C1Br)C([H])([H])C([H])([H])\C3=N\C([H])([H])C([H])([H])[H])C([H])([H])[H])C([H])([H])[H] [H]N(C(=O)OC1=C([H])C([H])=C2N(C3=C(C2=C1[H])C([H])([H])C([H])([H])\C3=N\C([H])([H])C([H])([H])[H])C([H])([H])[H])C([H])([H])[H] [H]C1=C([H])C([H])=C2C(=C1[H])N(C1=C2C([H])([H])C([H])([H])\C1=N\C([H])([H])C([H])([H])[H])C([H])([H])[H] [H]N(C(=O)OC1=C([H])C([H])=C2N(C3=C(C2=C1Br)C([H])([H])C([H])([H])\C3=N\C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H] [H]N1C([H])([H])C([H])([H])C([H])(C2=C([H])C3=C(O2)C(Br)=C([H])C(OC([H])([H])[H])=C3[H])C([H])([H])C1([H])[H] [H]OC1=C([H])C([H])=C(C2=NN(C(=O)C([H])([H])[H])C([H])([H])C2([H])[H])C(O[H])=C1O[H] [H]OC1=C([H])C([H])=C([H])C([H])=C1C1=NN(C(=O)C([H])([H])[H])C([H])([H])C1([H])[H] [H]C1=C([H])C([H])=C2C(=C1[H])N(C1=C2C([H])([H])C([H])([H])\C1=N\C([H])([H])[H])C([H])([H])[H] [H]C1=C([H])C([H])=C(C([H])=C1[H])C1=NN(C(=O)C([H])([H])[H])[C@@]([H])(C2=C([H])C([H])=C([H])C([H])=C2[H])C1([H])[H] [H]OC1=C([H])C(O[H])=C(C([H])=C1[H])C1=NN(C(=O)C([H])([H])[H])[C@]([H])(C2=C([H])C([H])=C([H])C([H])=C2[H])C1([H])[H] [H]OC1=C([H])C([H])=C([H])C(O[H])=C1C1=NN(C(=O)C([H])([H])[H])[C@@]([H])(C2=C([H])C([H])=C([H])C([H])=C2[H])C1([H])[H] [H]C1=C([H])C([H])=C(C([H])=C1[H])C1=NN(C(=O)C([H])([H])[H])[C@]([H])(C2=C([H])C([H])=C([H])C([H])=C2C([H])([H])[H])C1([H])[H] [H]OC1=C([H])C([H])=C([H])C(O[H])=C1C1=NN(C(=O)C([H])([H])[H])[C@@]([H])(C2=C(C([H])=C([H])C([H])=C2[H])C([H])([H])[H])C1([H])[H] [H]OC1=C([H])C([H])=C([H])C(O[H])=C1C1=NN(C(=O)C([H])([H])[H])[C@]([H])(C2=C([H])C([H])=C([H])C(=C2[H])C([H])([H])[H])C1([H])[H] [H]OC1=C(C([H])=C([H])C([H])=C1[H])C1=NN(C(=O)C([H])([H])[H])[C@@]([H])(C2=C([H])C([H])=C(Cl)C([H])=C2[H])C1([H])[H] [H]OC1=C([H])C([H])=C([H])C(O[H])=C1C1=NN(C(=O)C([H])([H])[H])[C@@]([H])(C2=C([H])C([H])=C(Cl)C([H])=C2[H])C1([H])[H] [H]OC1=C([H])C([H])=C([H])C(O[H])=C1C1=NN(C(=O)C([H])([H])[H])[C@@]([H])(C2=C([H])C([H])=C(OC([H])([H])[H])C([H])=C2[H])C1([H])[H] [H]C1=C([H])C([H])=C(C([H])=C1[H])C1=NN(C(=O)C([H])([H])[H])[C@@]([H])(C2=C(OC([H])([H])[H])C([H])=C(OC([H])([H])[H])C([H])=C2[H])C1([H])[H] [H]OC1=C(C([H])=C([H])C([H])=C1[H])C1=NN(C(=O)C([H])([H])[H])[C@@]([H])(C2=C(OC([H])([H])[H])C([H])=C(OC([H])([H])[H])C([H])=C2[H])C1([H])[H] [H]OC1=C([H])C(O[H])=C(C([H])=C1[H])C1=NN(C(=O)C([H])([H])[H])[C@@]([H])(C2=C(OC([H])([H])[H])C([H])=C(OC([H])([H])[H])C([H])=C2[H])C1([H])[H] [H]C1=C([H])C([H])=C(C([H])=C1[H])C1=NN(C(=O)C([H])([H])[H])[C@]([H])(C2=C([H])C([H])=C(OC([H])([H])[H])C(OC([H])([H])[H])=C2[H])C1([H])[H] [H]OC1=C(C([H])=C([H])C([H])=C1[H])C1=NN(C(=O)C([H])([H])[H])[C@@]([H])(C2=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C([H])=C2[H])C1([H])[H] [H]C1=C([H])C([H])=C(C([H])=C1[H])N1N=C(C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H] [H]C1=C([H])C([H])=C(C([H])=C1[H])N1N=C(C2=C([H])C([H])=C(Cl)C([H])=C2[H])C([H])([H])C1([H])[H] [H]C1=C([H])C([H])=C(C([H])=C1[H])N1N=C(C2=C([H])C([H])=C(Br)C([H])=C2[H])C([H])([H])C1([H])[H] [H]C1=C([H])C([H])=C(C([H])=C1[H])N1N=C(C2=C([H])C([H])=C(C([H])=C2[H])C([H])([H])[H])C([H])([H])C1([H])[H] [H]OC1=C(C([H])=C([H])C([H])=C1[H])C1=NN(C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H] [H]OC1=C([H])C([H])=C(C([H])=C1[H])C1=NN(C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H] [H]C1=C([H])C([H])=C(C([H])=C1[H])N1N=C(C2=C([H])C(OC([H])([H])[H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H] [H]C1=C([H])C([H])=C(C([H])=C1[H])N1N=C(C2=C([H])C([H])=C(OC([H])([H])[H])C([H])=C2[H])C([H])([H])C1([H])[H] [H]C1=C([H])C([H])=C(C([H])=C1[H])N1N=C(C2=C([H])C([H])=C(C([H])=C2[H])[N+]([O-])=O)C([H])([H])C1([H])[H] [H]C1=C([H])C([H])=C(C([H])=C1[H])N1N=C(C2=C(OC([H])([H])[H])C([H])=C(OC([H])([H])[H])C([H])=C2[H])C([H])([H])C1([H])[H] [H]C1=C([H])C([H])=C(C([H])=C1[H])N1N=C(C2=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C([H])=C2[H])C([H])([H])C1([H])[H] [H]C1=C([H])C([H])=C(C([H])=C1[H])C1=NN(C(=O)C([H])([H])[H])C([H])([H])C1([H])[H] [H]C1=C([H])C(=C([H])C([H])=C1C1=NN(C(=O)C([H])([H])[H])C([H])([H])C1([H])[H])C([H])([H])[H] [H]C1=C([H])C(=C([H])C([H])=C1Cl)C1=NN(C(=O)C([H])([H])[H])C([H])([H])C1([H])[H] [H]C1=C([H])C(=C([H])C([H])=C1Br)C1=NN(C(=O)C([H])([H])[H])C([H])([H])C1([H])[H] [H]C1=C([H])C(=C([H])C([H])=C1OC([H])([H])[H])C1=NN(C(=O)C([H])([H])[H])C([H])([H])C1([H])[H] [H]C1=C([H])C(=C([H])C(OC([H])([H])[H])=C1[H])C1=NN(C(=O)C([H])([H])[H])C([H])([H])C1([H])[H] [H]C1=C([H])C(OC([H])([H])[H])=C(C([H])=C1[H])C1=NN(C(=O)C([H])([H])[H])C([H])([H])C1([H])[H] [H]C1=C([H])C(C2=NN(C(=O)C([H])([H])[H])C([H])([H])C2([H])[H])=C(OC([H])([H])[H])C([H])=C1OC([H])([H])[H] [H]C1=C(OC([H])([H])[H])C(OC([H])([H])[H])=C([H])C(=C1[H])C1=NN(C(=O)C([H])([H])[H])C([H])([H])C1([H])[H] [H]C1=C(OC([H])([H])[H])C([H])=C(C2=NN(C(=O)C([H])([H])[H])C([H])([H])C2([H])[H])C(OC([H])([H])[H])=C1[H] [H]C1=C([H])C(C2=NN(C(=O)C([H])([H])[H])C([H])([H])C2([H])[H])=C(C([H])=C1[H])[N+]([O-])=O [H]OC1=C([H])C([H])=C(C([H])=C1[H])C1=NN(C(=O)C([H])([H])[H])C([H])([H])C1([H])[H] [H]OC1=C([H])C([H])=C(C2=NN(C(=O)C([H])([H])[H])C([H])([H])C2([H])[H])C(O[H])=C1[H] [H]N(C(=O)OC1=C([H])C([H])=C2N(C3=C(C2=C1Br)C([H])([H])C([H])([H])\C3=N\C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H] [H]N(C(=O)OC1=C([H])C([H])=C2N(C3=C(C2=C1Cl)C([H])([H])C([H])([H])\C3=N\C([H])([H])C([H])([H])[H])C([H])([H])[H])C([H])([H])[H] [H]N(C1=NOC([H])=C1[H])C([H])([H])[C@]1([H])OC(=O)N(C2=C([H])C(F)=C(C([H])=C2[H])C2=C([H])C(=NO2)C([H])([H])[H])C1([H])[H] [H]C1=C([H])N(N=N1)C([H])([H])[C@]1([H])OC(=O)N(C2=C([H])C(F)=C(C([H])=C2[H])C2=C([H])C(=NO2)C([H])([H])[H])C1([H])[H] [H]N(C(=O)C([H])([H])[H])C([H])([H])[C@]1([H])OC(=O)N(C2=C([H])C(F)=C(C([H])=C2[H])C2=C([H])C(=NO2)C([H])([H])[H])C1([H])[H] [H]C1=C([H])C(=C([H])S1)C1=C([H])C2=C([H])C([H])=C(OC([H])([H])[H])C([H])=C2OC1=O [H]N1C([H])=C(C2=C1C([H])=C([H])C([H])=C2[H])C1=C([H])C2=C([H])C([H])=C(OC([H])([H])[H])C([H])=C2OC1=O [H]N1N=C(C2=C3C([H])=C([H])C([H])=C([H])C3=C([H])C3=C([H])C([H])=C([H])C([H])=C23)C([H])([H])[C@@]1([H])C1=C([H])C([H])=C(C([H])=C1[H])[N+]([O-])=O [H]OC1=C([H])C([H])=C(C([H])=C1[H])[C@]1([H])N([H])N=C(C2=C3C([H])=C([H])C([H])=C([H])C3=C([H])C3=C([H])C([H])=C([H])C([H])=C23)C1([H])[H] [H]N1N=C(C2=C3C([H])=C([H])C([H])=C([H])C3=C([H])C3=C([H])C([H])=C([H])C([H])=C23)C([H])([H])[C@@]1([H])C1=C([H])C([H])=C(Cl)C([H])=C1[H] [H]N1N=C(C2=C3C([H])=C([H])C([H])=C([H])C3=C([H])C3=C([H])C([H])=C([H])C([H])=C23)C([H])([H])[C@@]1([H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H] [H]N1N=C(C2=C3C([H])=C([H])C([H])=C([H])C3=C([H])C3=C([H])C([H])=C([H])C([H])=C23)C([H])([H])[C@@]1([H])C1=C([H])C([H])=C([H])C([H])=C1[H] [H]OC1=C([H])C([H])=C([H])C([H])=C1[C@@]1([H])N([H])N=C(C2=C3C([H])=C([H])C([H])=C([H])C3=C([H])C3=C([H])C([H])=C([H])C([H])=C23)C1([H])[H] [H]OC1=C([H])C([H])=C(C(O[H])=C1[H])[C@@]1([H])N([H])N=C(C2=C3C([H])=C([H])C([H])=C([H])C3=C([H])C3=C([H])C([H])=C([H])C([H])=C23)C1([H])[H] [H]N1N=C(C2=C3C([H])=C([H])C([H])=C([H])C3=C([H])C3=C([H])C([H])=C([H])C([H])=C23)C([H])([H])[C@@]1([H])C1=C([H])C([H])=C([H])C([H])=N1 [H]N1N=C(C2=C3C([H])=C([H])C([H])=C([H])C3=C([H])C3=C([H])C([H])=C([H])C([H])=C23)C([H])([H])[C@@]1([H])C1=C([H])C([H])=C([H])C(=C1[H])[N+]([O-])=O [H]N1N=C(C2=C3C([H])=C([H])C([H])=C([H])C3=C([H])C3=C([H])C([H])=C([H])C([H])=C23)C([H])([H])[C@@]1([H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H] [H]N1C2=C(C([H])=C([H])C(OC([H])([H])[H])=C2[H])C2=C1C(=NC([H])=C2[H])C([H])([H])[H] [H]C1=C([H])C2=C(C([H])=C1[H])C(=C([H])C([H])=C2[H])C([H])([H])C1=C([H])C([H])=[N+](C([H])=C1[H])C([H])([H])[H] [H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])OC1=NC2=C(N1C([H])([H])[H])C(=O)N(C(=O)N2C([H])([H])[H])C([H])([H])[H] [H]C1=C([H])C(Cl)=C([H])C(=C1[H])C([H])([H])OC1=NC2=C(N1C([H])([H])[H])C(=O)N(C(=O)N2C([H])([H])[H])C([H])([H])[H] [H]C1=C([H])C(Br)=C([H])C(=C1[H])C([H])([H])OC1=NC2=C(N1C([H])([H])[H])C(=O)N(C(=O)N2C([H])([H])[H])C([H])([H])[H] [H]C1=C([H])C(F)=C([H])C(=C1[H])C([H])([H])OC1=NC2=C(N1C([H])([H])[H])C(=O)N(C(=O)N2C([H])([H])[H])C([H])([H])[H] [H]C1=C([H])C(=C([H])C(=C1[H])C([H])([H])OC1=NC2=C(N1C([H])([H])[H])C(=O)N(C(=O)N2C([H])([H])[H])C([H])([H])[H])C(F)(F)F [H]C1=C([H])C(=C([H])C(=C1[H])C([H])([H])OC1=NC2=C(N1C([H])([H])[H])C(=O)N(C(=O)N2C([H])([H])[H])C([H])([H])[H])C([H])([H])[H] [H]C1=C([H])C(OC([H])([H])[H])=C([H])C(=C1[H])C([H])([H])OC1=NC2=C(N1C([H])([H])[H])C(=O)N(C(=O)N2C([H])([H])[H])C([H])([H])[H] [H]OC1=C([H])C([H])=C([H])C([H])=C1C1=NN(C(=S)N([H])C2=C([H])C([H])=C([H])C([H])=C2[H])[C@]([H])(C2=C([H])C([H])=C([H])S2)C1([H])[H] [H]OC1=C([H])C(O[H])=C2C(=O)C([H])=C(OC2=C1[H])C1=C([H])C(O[H])=C(O[H])C([H])=C1[H] [H]OC1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C(=O)C2=C(O[H])C([H])=C(O[H])C([H])=C2O1 [H]OC1=C([H])C(O[H])=C2C(=O)C(O[H])=C(OC2=C1[H])C1=C([H])C(O[H])=C(O[H])C([H])=C1[H] [H]N1C([H])([H])C([H])([H])S[C@]([H])(C2=C([H])C([H])=C(OC([H])([H])C([H])([H])[H])C([H])=C2[H])C1([H])[H] [H]N1C([H])([H])C([H])([H])S[C@]([H])(C2=C([H])C([H])=C(OC([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])=C2[H])C1([H])[H] [H]N1C([H])([H])C([H])([H])S[C@]([H])(C2=C([H])C([H])=C(OC([H])([H])C([H])([H])C([H])([H])[H])C([H])=C2[H])C1([H])[H] [H]N([H])C(=O)C1=C([H])C(=C(N=C1[H])C1=NC2=NC([H])=C([H])C(N([H])C3=NC([H])=C(C([H])=C3[H])C(F)(F)F)=C2N=C1[H])C(F)(F)F [H]N(N=C(C([H])([H])[H])C([H])([H])[H])C1=NC(=C([H])S1)C1=C([H])C([H])=C([H])C(OC([H])([H])[H])=C1[H] [H]N(N=C(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H])C1=NC(=C([H])S1)C1=C([H])C([H])=C([H])C(OC([H])([H])[H])=C1[H] [H]N(\N=C(/C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[H])C1=NC(=C([H])S1)C1=C([H])C([H])=C([H])C(OC([H])([H])[H])=C1[H] [H]N(\N=C(/C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C1=NC(=C([H])S1)C1=C([H])C([H])=C([H])C(OC([H])([H])[H])=C1[H] [H]N(N=C1C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C1=NC(=C([H])S1)C1=C([H])C([H])=C([H])C(OC([H])([H])[H])=C1[H] [H]N(\N=C1/C([H])([H])C([H])([H])C([H])([H])[C@]1([H])C([H])([H])[H])C1=NC(=C([H])S1)C1=C([H])C([H])=C([H])C(OC([H])([H])[H])=C1[H] [H]N(\N=C(/[H])C1=C([H])C([H])=C([H])O1)C1=NC(=C([H])S1)C1=C([H])C([H])=C([H])C(OC([H])([H])[H])=C1[H] [H]N(\N=C(\C1=C([H])C([H])=C([H])O1)C([H])([H])[H])C1=NC(=C([H])S1)C1=C([H])C([H])=C([H])C(OC([H])([H])[H])=C1[H] [H]N(\N=C(/[H])C1=C([H])C([H])=C([H])S1)C1=NC(=C([H])S1)C1=C([H])C([H])=C([H])C(OC([H])([H])[H])=C1[H] [H]N(\N=C(\C1=C([H])C([H])=C([H])S1)C([H])([H])[H])C1=NC(=C([H])S1)C1=C([H])C([H])=C([H])C(OC([H])([H])[H])=C1[H] [H]N(\N=C(/[H])C1=C([H])C([H])=C([H])N=C1[H])C1=NC(=C([H])S1)C1=C([H])C([H])=C([H])C(OC([H])([H])[H])=C1[H] [H]N(\N=C(\C1=C([H])C([H])=C([H])N=C1[H])C([H])([H])[H])C1=NC(=C([H])S1)C1=C([H])C([H])=C([H])C(OC([H])([H])[H])=C1[H] C[C@@H]1CCCC\C1=N/NC1=NC(=CS1)C1=CC=C(C=C1)C#N COC1=CC=C(C=C1)C1=CSC(NN=C2CCCCCC2)=N1 CC1=CC=C(C=C1)C1=CSC(NN=C2CCCCCC2)=N1 N#CC1=CC=C(C=C1)C1=CSC(NN=C2CCCCC2)=N1 [H]N(N=C1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C1=NC(=C([H])S1)C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H] FC1=CC=C(C=C1)C1=CSC(NN=C2CCCCC2)=N1 ClC1=CC=C(C=C1)C1=CSC(NN=C2CCCCC2)=N1 [H]N(N=C1C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C1=NC(=C([H])S1)C1=C([H])C([H])=C(C#N)C([H])=C1[H] [H]N(N=C1C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C1=NC(=C([H])S1)C1=C([H])C([H])=C(C([H])=C1[H])[N+]([O-])=O [H]N(N=C1C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C1=NC(=C([H])S1)C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H] [H]N(N=C1C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C1=NC(=C([H])S1)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H] FC1=CC(F)=C(C=C1)C1=CSC(NN=C2CCCC2)=N1 FC1=CC=C(C=C1)C1=CSC(NN=C2CCCC2)=N1 [H]N(N=C1C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C1=NC(=C([H])S1)C1=C([H])C([H])=C(Cl)C([H])=C1[H] [H]N(N=C1C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C1=NC(=C([H])S1)C1=C([H])C([H])=C([H])C([H])=C1[H] [H]N(\N=C(/[H])C1=C2OC([H])([H])OC2=C([H])C([H])=C1[H])C1=NC(=C([H])S1)C1=C([H])C([H])=C([H])C(OC([H])([H])[H])=C1[H] [H]N(\N=C(/[H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H])C1=NC(=C([H])S1)C1=C([H])C([H])=C([H])C(OC([H])([H])[H])=C1[H] [H]N(\N=C(\C1=C([H])C2=C(OC1=O)C([H])=C([H])C([H])=C2[H])C([H])([H])[H])C1=NC(=C([H])S1)C1=C([H])C([H])=C([H])C(OC([H])([H])[H])=C1[H] [H]N(\N=C(/[H])C1=C([H])C([H])=NC([H])=C1[H])C1=NC(=C([H])S1)C1=C([H])C([H])=C([H])C(OC([H])([H])[H])=C1[H] [H]N(\N=C(\C1=C([H])C([H])=NC([H])=C1[H])C([H])([H])[H])C1=NC(=C([H])S1)C1=C([H])C([H])=C([H])C(OC([H])([H])[H])=C1[H] [H]N(\N=C(/[H])C1=C2C([H])=C([H])C([H])=C([H])C2=C([H])C([H])=C1[H])C1=NC(=C([H])S1)C1=C([H])C([H])=C([H])C(OC([H])([H])[H])=C1[H] ClC1=CC(=CC=C1)C(=O)OC1=CC2=C(OC(=O)C2)C=C1 O=C(OC1=CC2=C(OC(=O)C2)C=C1)\C=C\C1=CC=CC=C1 ClC1=CC(\C=C\C(=O)OC2=CC3=C(OC(=O)C3)C=C2)=CC=C1 CC1=CC2=C(N1)C=CC(NC(=O)\C=C\C1=CC=CC(Cl)=C1)=C2 CC1=CC2=C(N1)C=CC(NC(=O)C1=CC=C(Cl)C(Cl)=C1)=C2 O=C(OC1=CC2=C(OC(=O)C2)C=C1)C1=CC=CC=C1 NCC1=CN(N=N1)C1=CC=CC=C1 NCC1=CN(N=N1)C1=CC=NC=C1 [H]N1C2=C([H])C(OC([H])([H])C3=C([H])C([H])=NC([H])=C3[H])=C([H])C([H])=C2C2=C1C(=NC([H])=C2[H])C([H])([H])[H] [H]N1C2=C([H])C(OC([H])([H])C3=C([H])C4=C([H])C([H])=C([H])C([H])=C4C([H])=C3[H])=C([H])C([H])=C2C2=C1C(=NC([H])=C2[H])C([H])([H])[H] [H]N1C2=C([H])C(OC([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H])=C([H])C([H])=C2C2=C1C(=NC([H])=C2[H])C([H])([H])[H] [H]N1C2=C([H])C(OC([H])([H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H])=C([H])C([H])=C2C2=C1C(=NC([H])=C2[H])C([H])([H])[H] [H]N1C2=C([H])C(OC([H])([H])C([H])([H])N3C([H])([H])C([H])([H])OC([H])([H])C3([H])[H])=C([H])C([H])=C2C2=C1C(=NC([H])=C2[H])C([H])([H])[H] [H]C([H])=C([H])C([H])([H])OC1=C([H])C([H])=C2C(N([H])C3=C2C([H])=C([H])N=C3C([H])([H])[H])=C1[H] [H]N1C2=C([H])C(OC([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])=C([H])C([H])=C2C2=C1C(=NC([H])=C2[H])C([H])([H])[H] [H]N1C2=C([H])C(OC([H])([H])C([H])([H])OC([H])([H])[H])=C([H])C([H])=C2C2=C1C(=NC([H])=C2[H])C([H])([H])[H] [H]OC([H])([H])C([H])([H])OC1=C([H])C2=C(C([H])=C1[H])C1=C([H])C([H])=NC(=C1N2[H])C([H])([H])[H] [H]N1C2=C([H])C(OC([H])([H])C([H])([H])C([H])([H])C(F)(F)F)=C([H])C([H])=C2C2=C1C(=NC([H])=C2[H])C([H])([H])[H] [H]N1C2=C([H])C(OC([H])([H])C3([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C3([H])[H])=C([H])C([H])=C2C2=C1C(=NC([H])=C2[H])C([H])([H])[H] [H]N1C2=C([H])C(OC([H])([H])C([H])([H])C3=C([H])C([H])=C([H])C([H])=C3[H])=C([H])C([H])=C2C2=C1C(=NC([H])=C2[H])C([H])([H])[H] [H]N1C2=C([H])C(OC([H])([H])C3=NC([H])=C([H])C([H])=C3[H])=C([H])C([H])=C2C2=C1C(=NC([H])=C2[H])C([H])([H])[H] [H]N1C2=C([H])C(OC([H])([H])C3=C([H])N=C([H])C([H])=C3[H])=C([H])C([H])=C2C2=C1C(=NC([H])=C2[H])C([H])([H])[H] [H]N1C(=O)C(=O)C2=C([H])C(OC([H])([H])C3=C([H])C([H])=C([H])C([H])=C3[H])=C([H])C([H])=C12 [H]N1C(=O)C(=O)C2=C([H])C(=C([H])C([H])=C12)C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H] [H]N1C(=O)C(=O)C2=C([H])C([H])=C(C([H])=C12)C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H] [H]N1C(=O)C(=O)C2=C([H])C(OC3=C([H])C([H])=C([H])C([H])=C3[H])=C([H])C([H])=C12 [H]N1C(=O)C(=O)C2=C([H])C(=C([H])C([H])=C12)C1=C([H])C([H])=C([H])C([H])=C1[H] [H]N1C(=O)C(=O)C2=C([H])C([H])=C(C([H])=C12)C1=C([H])C([H])=C([H])C([H])=C1[H] [H]N1C(=O)C(=O)C2=C([H])C(=C([H])C([H])=C12)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H] [H]N1C(=O)C(=O)C2=C([H])C(OC3=C([H])C([H])=C(Cl)C([H])=C3[H])=C([H])C([H])=C12 [H]OC1=C(N([H])[H])C([H])=C(\C([H])=C2\C(=O)C3=C(OC2([H])[H])C([H])=C([H])C([H])=C3[H])C([H])=C1[H] [H]OC1=C(O[H])C([H])=C(\C([H])=C2\C(=O)C3=C([H])C([H])=C([H])C([H])=C3OC2([H])[H])C([H])=C1[H] [H]N(C(=O)C([H])([H])[H])C1=C([H])C([H])=C(\C([H])=C2\C(=O)C3=C([H])C([H])=C([H])C([H])=C3OC2([H])[H])C([H])=C1[H] [H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])OC1=C([H])C(C#N)=C(C#N)C([H])=C1[H] [H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])OC1=C([H])C(C#N)=C(C#N)C([H])=C1[H] [H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])OC1=C([H])C(C#N)=C(C#N)C([H])=C1[H] [H]\C(=C(\[H])C([H])([H])OC1=C([H])C(C#N)=C(C#N)C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H] [H]C1=C([H])C2=C([H])C([H])=C(OC3=C([H])C(C#N)=C(C#N)C([H])=C3[H])C([H])=C2C([H])=C1[H] [H]C1=C([H])C(=C([H])C([H])=C1Br)C([H])([H])OC1=C([H])C(C#N)=C(C#N)C([H])=C1[H] [H]C1=C([H])C(=C([H])C([H])=C1Br)C([H])([H])C([H])([H])OC1=C([H])C(C#N)=C(C#N)C([H])=C1[H] [H]\C(=C(\[H])C([H])([H])OC1=C([H])C(C#N)=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H] [H]C1=C([H])C(OC2=C([H])C([H])=C(C#N)C([H])=C2[H])=C([H])C([H])=C1Br [H]C1=C([H])C(OC([H])([H])C2=C([H])C([H])=C(Br)C([H])=C2[H])=C([H])C(C#N)=C1[H] [H]OC1=C([H])C([H])=C([H])C([H])=C1[C@@]1([H])N(N=C(C2=C([H])C([H])=C([H])C([H])=C2[H])C1([H])[H])C(=S)N([H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H] [H]OC1=C([H])C([H])=C([H])C([H])=C1[C@@]1([H])N(N=C(C2=C([H])C([H])=C([H])C([H])=C2[H])C1([H])[H])C(=S)N([H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H] [H]OC1=C([H])C([H])=C([H])C([H])=C1[C@@]1([H])N(N=C(C2=C([H])C([H])=C([H])C([H])=C2[H])C1([H])[H])C(=S)N([H])C1=C([H])C(OC([H])([H])[H])=C([H])C([H])=C1[H] [H]OC1=C([H])C([H])=C([H])C([H])=C1[C@@]1([H])N(N=C(C2=C([H])C([H])=C([H])C([H])=C2[H])C1([H])[H])C(=S)N([H])C1=C([H])C(=C([H])C([H])=C1[H])C([H])([H])[H] [H]OC1=C([H])C([H])=C([H])C([H])=C1[C@@]1([H])N(N=C(C2=C([H])C([H])=C([H])C([H])=C2[H])C1([H])[H])C(=S)N([H])C1=C(OC([H])([H])[H])C([H])=C([H])C([H])=C1[H] [H]OC1=C([H])C([H])=C([H])C([H])=C1[C@@]1([H])N(N=C(C2=C([H])C([H])=C([H])C([H])=C2[H])C1([H])[H])C(=S)N([H])C1=C(C([H])=C([H])C([H])=C1[H])C([H])([H])[H] [H]OC1=C([H])C([H])=C(C([H])=C1[H])[C@@]1([H])N(N=C(C2=C([H])C([H])=C([H])C([H])=C2[H])C1([H])[H])C(=S)N([H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H] [H]OC1=C([H])C([H])=C(C([H])=C1[H])[C@@]1([H])N(N=C(C2=C([H])C([H])=C([H])C([H])=C2[H])C1([H])[H])C(=S)N([H])C1=C([H])C([H])=C([H])C(OC([H])([H])[H])=C1[H] [H]OC1=C([H])C([H])=C(C([H])=C1[H])[C@@]1([H])N(N=C(C2=C([H])C([H])=C([H])C([H])=C2[H])C1([H])[H])C(=S)N([H])C1=C([H])C([H])=C([H])C(=C1[H])C([H])([H])[H] [H]OC1=C([H])C([H])=C(C([H])=C1[H])[C@]1([H])N(N=C(C2=C([H])C([H])=C([H])C([H])=C2[H])C1([H])[H])C(=S)N([H])C1=C([H])C([H])=C([H])C([H])=C1OC([H])([H])[H] [H]OC1=C([H])C([H])=C(C([H])=C1[H])[C@@]1([H])N(N=C(C2=C([H])C([H])=C([H])C([H])=C2[H])C1([H])[H])C(=S)N([H])C1=C([H])C([H])=C([H])C([H])=C1C([H])([H])[H] [H]N([H])C(=O)N1N=C(C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])[C@@]1([H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H] [H]N([H])C(=O)N1N=C(C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])[C@@]1([H])C1=C([H])C([H])=NC([H])=C1[H] [H]N([H])C(=O)N1N=C(C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])[C@@]1([H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H] [H]N([H])C(=O)N1N=C(C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])[C@@]1([H])C1=C([H])C([H])=C(Cl)C([H])=C1[H] [H]N([H])C(=S)N1N=C(C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])[C@@]1([H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H] [H]N([H])C(=S)N1N=C(C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])[C@@]1([H])C1=C([H])C([H])=NC([H])=C1[H] [H]N([H])C(=S)N1N=C(C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])[C@@]1([H])C1=C([H])C([H])=C(Cl)C([H])=C1[H] [H]N=C(N([H])[H])N1N=C(C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])[C@@]1([H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H] [H]N=C(N([H])[H])N1N=C(C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])[C@@]1([H])C1=C([H])C([H])=C(Cl)C([H])=C1[H] [H]N=C(N([H])[H])N1N=C(C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])[C@@]1([H])C1=C([H])C([H])=NC([H])=C1[H] [H]OC1=C([H])C([H])=C(C([H])=C1[H])[C@@]1([H])N(N=C(C2=C([H])C([H])=C([H])C([H])=C2[H])C1([H])[H])C(=S)N([H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H] [H]N1C(=O)C2=C([H])C([H])=C(OC3=C([H])C([H])=C([H])C([H])=C3[H])C([H])=C2C1=O [H]N1C(=O)C2=C([H])C([H])=C(OC([H])([H])C3=C([H])C([H])=C([H])C([H])=C3[H])C([H])=C2C1=O [H]N1C(=O)C2=C([H])C([H])=C(OC([H])([H])C([H])([H])C3=C([H])C([H])=C([H])C([H])=C3[H])C([H])=C2C1=O [H]N1C(=O)C2=C([H])C([H])=C(OC([H])([H])C([H])([H])C([H])([H])C3=C([H])C([H])=C([H])C([H])=C3[H])C([H])=C2C1=O [H]N1C(=O)C2=C([H])C([H])=C(OC([H])([H])C(\[H])=C(/[H])C3=C([H])C([H])=C([H])C([H])=C3[H])C([H])=C2C1=O [H]N1C(=O)C2=C([H])C([H])=C(OC3=C([H])C([H])=C4C([H])=C([H])C([H])=C([H])C4=C3[H])C([H])=C2C1=O [H]N1C(=O)C2=C([H])C([H])=C(OC([H])([H])C3=C([H])C([H])=C(Br)C([H])=C3[H])C([H])=C2C1=O [H]N1C(=O)C2=C([H])C([H])=C(OC([H])([H])C([H])([H])C3=C([H])C([H])=C(Br)C([H])=C3[H])C([H])=C2C1=O [H]N1C(=O)C2=C([H])C([H])=C(OC3=C([H])C([H])=C(Br)C([H])=C3[H])C([H])=C2C1=O [H]C1=C([H])C(=C([H])C([H])=C1Cl)C([H])([H])OC1=NC2=C(N1C([H])([H])[H])C(=O)N(C(=O)N2C([H])([H])[H])C([H])([H])[H] [H]C1=C([H])C(=C([H])C([H])=C1Br)C([H])([H])OC1=NC2=C(N1C([H])([H])[H])C(=O)N(C(=O)N2C([H])([H])[H])C([H])([H])[H] [H]C1=C([H])C([H])([H])[C@]([H])(C([H])([H])OC2=NC3=C(N2C([H])([H])[H])C(=O)N(C(=O)N3C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H] [H]C1=C([H])C(OC([H])([H])C([H])([H])OC2=NC3=C(N2C([H])([H])[H])C(=O)N(C(=O)N3C([H])([H])[H])C([H])([H])[H])=C([H])C([H])=C1Cl [H]C1=C([H])C(OC([H])([H])C([H])([H])OC2=NC3=C(N2C([H])([H])[H])C(=O)N(C(=O)N3C([H])([H])[H])C([H])([H])[H])=C([H])C([H])=C1Br [H]OC1=C([H])C([H])=C(N([H])C(=O)C2=C([H])C(=O)C3=C([H])C([H])=C([H])C([H])=C3O2)C([H])=C1O[H] [H]OC1=C([H])C([H])=C(N([H])C(=O)C2=C([H])OC3=C([H])C([H])=C([H])C([H])=C3C2=O)C([H])=C1O[H] [H]OC1=C([H])C([H])=C(N([H])C(=O)C2=C([H])OC3=C([H])C([H])=C([H])C([H])=C3C2=O)C([H])=C1[H] [H]OC1=C([H])C(N([H])C(=O)C2=C([H])OC3=C([H])C([H])=C([H])C([H])=C3C2=O)=C([H])C([H])=C1OC([H])([H])[H] [H]C1=C([H])C(=O)C2=C(O1)C([H])=C([H])C(OC([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])=C2[H] [H]C1=C([H])C(=O)C2=C([H])C(OC([H])([H])C([H])([H])C3=C([H])C([H])=C([H])C([H])=C3[H])=C([H])C([H])=C2O1 [H]C1=C([H])C(=O)C2=C([H])C(OC([H])([H])C([H])([H])C([H])([H])C3=C([H])C([H])=C([H])C([H])=C3[H])=C([H])C([H])=C2O1 [H]C1=C([H])C(=O)C2=C([H])C(OC([H])([H])C3=C([H])C(Cl)=C([H])C([H])=C3[H])=C([H])C([H])=C2O1 [H]C1=C([H])C(=O)C2=C([H])C(OC([H])([H])C3=C([H])C([H])=C(Cl)C([H])=C3[H])=C([H])C([H])=C2O1 [H]C1=C([H])C(=O)C2=C([H])C(OC([H])([H])C3=C([H])C(Br)=C([H])C([H])=C3[H])=C([H])C([H])=C2O1 [H]C1=C([H])C(=O)C2=C([H])C(OC([H])([H])C3=C([H])C([H])=C(Br)C([H])=C3[H])=C([H])C([H])=C2O1 [H]C1=C([H])C(=O)C2=C([H])C(OC([H])([H])C3=C([H])C(F)=C([H])C([H])=C3[H])=C([H])C([H])=C2O1 [H]C1=C([H])C(=O)C2=C([H])C(OC([H])([H])C3=C([H])C([H])=C(F)C([H])=C3[H])=C([H])C([H])=C2O1 [H]C1=C([H])C(=O)C2=C([H])C(OC([H])([H])C3=C([H])C(=C([H])C([H])=C3[H])C([H])([H])[H])=C([H])C([H])=C2O1 [H]C1=C([H])C(=O)C2=C([H])C(OC([H])([H])C3=C([H])C([H])=C(C([H])=C3[H])C([H])([H])[H])=C([H])C([H])=C2O1 [H]C1=C([H])C(=O)C2=C([H])C(OC([H])([H])C3=C([H])C(C#N)=C([H])C([H])=C3[H])=C([H])C([H])=C2O1 [H]C1=C([H])C(=O)C2=C([H])C(OC([H])([H])C3=C([H])C([H])=C(C#N)C([H])=C3[H])=C([H])C([H])=C2O1 [H]C1=C([H])C(=O)C2=C([H])C(OC([H])([H])C3=C([H])C([H])=C(C([H])=C3[H])C(F)(F)F)=C([H])C([H])=C2O1 [H]C1=C([H])C(=O)C2=C([H])C(OC([H])([H])C([H])([H])C3=C([H])C([H])=C(Br)C([H])=C3[H])=C([H])C([H])=C2O1 [H]C1=C([H])C([H])=C(C([H])=C1[H])C1=NN(C2=C([H])C([H])=C(C([H])=C2[H])[N+]([O-])=O)[C@@]([H])(OC([H])([H])C([H])([H])[H])C1([H])[H] [H]\C(=C1\OC2=C([H])C([H])=C([H])C([H])=C2C1=O)C1=C([H])C([H])=C(C([H])=C1[H])N(C([H])([H])[H])C([H])([H])[H] [H]\C(=C1\OC2=C([H])C([H])=C([H])C([H])=C2C1=O)C1=C([H])C([H])=C(Cl)C([H])=C1[H] [H]OC1=C([H])C([H])=C2C(O\C(=C(\[H])C3=C([H])C([H])=C(C([H])=C3[H])N(C([H])([H])[H])C([H])([H])[H])C2=O)=C1[H] [H]N([H])C([H])([H])C([H])([H])C([H])([H])[C@@]([H])(N([H])C1=C2N=C([H])C([H])=C(C2=C(OC2=C([H])C(F)=C([H])C([H])=C2[H])C(OC([H])([H])[H])=C1[H])C([H])([H])[H])C([H])([H])[H] [H]N([H])C([H])([H])C([H])([H])C([H])([H])[C@]([H])(N([H])C1=C2N=C([H])C([H])=C(C2=C(OC2=C([H])C([H])=C(F)C([H])=C2[H])C(OC([H])([H])[H])=C1[H])C([H])([H])[H])C([H])([H])[H] [H]N([H])C([H])([H])C([H])([H])C([H])([H])[C@@]([H])(N([H])C1=C2N=C([H])C([H])=C(C2=C(OC2=C([H])C([H])=C(C([H])=C2[H])C(F)(F)F)C(OC([H])([H])[H])=C1[H])C([H])([H])[H])C([H])([H])[H] [H]N([H])C([H])([H])C([H])([H])C([H])([H])[C@@]([H])(N([H])C1=C2N=C([H])C([H])=C(C2=C(OC2=C([H])C(Cl)=C([H])C([H])=C2[H])C(OC([H])([H])[H])=C1[H])C([H])([H])[H])C([H])([H])[H] [H]N([H])C([H])([H])C([H])([H])C([H])([H])[C@]([H])(N([H])C1=C2N=C([H])C([H])=C(C2=C(OC2=C(Cl)C([H])=C(Cl)C([H])=C2[H])C(OC([H])([H])[H])=C1[H])C([H])([H])[H])C([H])([H])[H] [H]N([H])C([H])([H])C([H])([H])C([H])([H])[C@@]([H])(N([H])C1=C2N=C([H])C([H])=C(C2=C(OC2=C(Cl)C([H])=C(Cl)C(Cl)=C2[H])C(OC([H])([H])[H])=C1[H])C([H])([H])[H])C([H])([H])[H] [H]N([H])C([H])([H])C([H])([H])C([H])([H])[C@]([H])(N([H])C1=C2N=C([H])C([H])=C(C2=C(OC2=C([H])C(Cl)=C(Cl)C([H])=C2[H])C(OC([H])([H])[H])=C1[H])C([H])([H])[H])C([H])([H])[H] [H]C1=C(OC([H])([H])[H])C([H])=C2C(=C1[H])C([H])=[N+](C([H])([H])[H])C([H])([H])C2([H])[H] [H]C1=C2C([H])=[N+](C([H])([H])[H])C([H])([H])C([H])([H])C2=C([H])C(OC([H])([H])[H])=C1OC([H])([H])[H] [H]C1=C2C(=NC([H])([H])C([H])([H])C2=C([H])C(OC([H])([H])[H])=C1OC([H])([H])[H])C([H])([H])[H] [H]C1=C2C(=C(OC([H])([H])[H])C(OC([H])([H])[H])=C1OC([H])([H])[H])C(=NC([H])([H])C2([H])[H])C([H])([H])[H] [H]C1=C([H])C2=C(C([H])=C1[H])C1=NC([H])([H])C([H])([H])C3=C([H])C(OC([H])([H])[H])=C([H])C(C2=O)=C13 [H]OC1=C(OC([H])([H])[H])C([H])=C2C3=C1C(=O)C1=C(C([H])=C([H])C([H])=C1[H])C3=NC([H])([H])C2([H])[H] [H]C1=NC2=C3C(C([H])=C([H])C([H])=C3C(=O)C3=C2C([H])=C([H])C([H])=C3[H])=C1[H] [H]C1=C([H])C2=C([H])C(OC([H])([H])[H])=C([H])C3=C2C(=N1)C1=C(C([H])=C([H])C([H])=C1[H])C3=O [H]OC1=C(OC([H])([H])[H])C([H])=C2C([H])=C([H])N=C3C4=C(C([H])=C([H])C([H])=C4[H])C(=O)C1=C23 [H]OC1=C([H])C2=C3C(=NC([H])=C([H])C3=C1[H])C1=C(C([H])=C([H])C([H])=C1[H])C2=O [H]C1=C([H])C2=C3C(=N1)C1=C(C([H])=C([H])C([H])=C1[H])C([H])=C3C(=O)C(OC([H])([H])[H])=C2[H] [H]C1=C(OC([H])([H])[H])C([H])=C2C3=C1C(=O)C1=C(C3=NC([H])([H])C2([H])[H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H] [H]O[C@]1([H])C2=C(C([H])=C([H])C([H])=C2[H])[C@@]2([H])N([H])C([H])([H])C([H])([H])C3=C([H])C(OC([H])([H])[H])=C([H])C1=C23 [H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])SC1=NC2=C(N1C([H])([H])[H])C(=O)N(C(=O)N2C([H])([H])[H])C([H])([H])[H] [H]C1=C([H])C(=C([H])C([H])=C1Cl)C([H])([H])SC1=NC2=C(N1C([H])([H])[H])C(=O)N(C(=O)N2C([H])([H])[H])C([H])([H])[H] [H]C1=C([H])C(=C([H])C([H])=C1Br)C([H])([H])SC1=NC2=C(N1C([H])([H])[H])C(=O)N(C(=O)N2C([H])([H])[H])C([H])([H])[H] [H]C1=C([H])C(=C([H])C([H])=C1F)C([H])([H])SC1=NC2=C(N1C([H])([H])[H])C(=O)N(C(=O)N2C([H])([H])[H])C([H])([H])[H] [H]C([H])([H])N1C(SC2([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])=NC2=C1C(=O)N(C(=O)N2C([H])([H])[H])C([H])([H])[H] [H]N(C1=NC2=C(N1C([H])([H])[H])C(=O)N(C(=O)N2C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C1=C([H])C(Cl)=C([H])C([H])=C1[H] [H]C1=C([H])C2=C(C([H])=C1[H])C(=O)C([H])=C([H])C2=O [H]C1=C(C([H])=C2C(=O)C(=C(C(=O)C2=C1[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])[H] [H]C1=C(Cl)C([H])=C(Cl)C(=C1[H])C([H])([H])C([H])([H])N1C([H])([H])C([H])=C([H])C([H])([H])C1([H])[H] [H]C1=C(Cl)C([H])=C(Cl)C(OC([H])([H])C([H])([H])C([H])([H])N2C([H])([H])C([H])=C([H])C([H])([H])C2([H])[H])=C1[H] [H]C#CC([H])([H])N(C([H])([H])[H])[C@]([H])(C([H])([H])F)C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H] [H]N([H])[C@]1([H])C([H])([H])[C@@]1([H])C1=C([H])C([H])=C(N([H])C(=O)[C@@]([H])(N([H])C(=O)OC([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])=C1[H] [H]OC1=C([H])C([H])=C(C2=NN(C(=O)C([H])([H])[H])[C@@]([H])(C3=C([H])C([H])=C([H])C([H])=C3OC([H])([H])[H])C2([H])[H])C(O[H])=C1[H] [H]OC1=C([H])C([H])=C(C([H])=C1[H])C1=NN(C(=O)C([H])([H])[H])[C@@]([H])(C2=C([H])C([H])=C([H])C([H])=C2Cl)C1([H])[H] [H]OC1=C([H])C([H])=C(C([H])=C1[H])C1=NN(C(=O)C([H])([H])[H])[C@@]([H])(C2=C([H])C([H])=C(C([H])=C2[H])C([H])([H])[H])C1([H])[H] [H]OC1=C([H])C([H])=C(C([H])=C1[H])C1=NN(C(=O)C([H])([H])[H])[C@]([H])(C2=C([H])C([H])=C([H])C([H])=C2OC([H])([H])[H])C1([H])[H] [H]OC1=C([H])C([H])=C(C([H])=C1[H])C1=NN(C(=O)C([H])([H])[H])[C@]([H])(C2=C([H])C([H])=C([H])C(=C2[H])C([H])([H])[H])C1([H])[H] [H]OC1=C([H])C([H])=C(C([H])=C1[H])C1=NN(C(=O)C([H])([H])[H])[C@]([H])(C2=C([H])C([H])=C(Cl)C([H])=C2[H])C1([H])[H] [H]OC1=C([H])C([H])=C(C([H])=C1[H])C1=NN(C(=O)C([H])([H])[H])[C@]([H])(C2=C([H])C([H])=C([H])C(Cl)=C2[H])C1([H])[H] [H]OC1=C([H])C([H])=C(C2=NN(C(=O)C([H])([H])[H])[C@@]([H])(C3=C([H])C([H])=C(OC([H])([H])[H])C([H])=C3[H])C2([H])[H])C(O[H])=C1[H] [H]OC1=C([H])C([H])=C(C2=NN(C(=O)C([H])([H])[H])[C@@]([H])(C3=C([H])C([H])=C(C([H])=C3[H])C([H])([H])[H])C2([H])[H])C(O[H])=C1[H] [H]OC1=C([H])C([H])=C(C([H])=C1[H])C1=NN(C(=O)C([H])([H])[H])[C@@]([H])(C2=C([H])C([H])=C(OC([H])([H])[H])C([H])=C2[H])C1([H])[H] [H]OC1=C([H])C([H])=C(C([H])=C1[H])C1=NN(C(=O)C([H])([H])[H])[C@@]([H])(C2=C([H])C([H])=C(OC([H])([H])[H])C([H])=C2OC([H])([H])[H])C1([H])[H] [H]OC1=C([H])C([H])=C(C2=NN(C(=O)C([H])([H])[H])[C@@]([H])(C3=C([H])C([H])=C(Cl)C([H])=C3[H])C2([H])[H])C(O[H])=C1[H] [H]C1=C([H])C(=O)C2=C(O1)C([H])=C(OC([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])=C2[H] [H]C1=C([H])C(=O)C2=C(O1)C([H])=C(OC([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])=C2[H] [H]C1=C([H])C(=O)C2=C(O1)C([H])=C(OC([H])([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])=C2[H] [H]C1=C([H])C(=O)C2=C(O1)C([H])=C(OC([H])([H])C1=C([H])C([H])=C([H])C(Cl)=C1[H])C([H])=C2[H] [H]C1=C([H])C(=O)C2=C(O1)C([H])=C(OC([H])([H])C1=C([H])C([H])=C(Cl)C([H])=C1[H])C([H])=C2[H] [H]C1=C([H])C(=O)C2=C(O1)C([H])=C(OC([H])([H])C1=C([H])C([H])=C([H])C(Br)=C1[H])C([H])=C2[H] [H]C1=C([H])C(=O)C2=C(O1)C([H])=C(OC([H])([H])C1=C([H])C([H])=C(Br)C([H])=C1[H])C([H])=C2[H] [H]C1=C([H])C(=O)C2=C(O1)C([H])=C(OC([H])([H])C1=C([H])C([H])=C([H])C(F)=C1[H])C([H])=C2[H] [H]C1=C([H])C(=O)C2=C(O1)C([H])=C(OC([H])([H])C1=C([H])C([H])=C(F)C([H])=C1[H])C([H])=C2[H] [H]C1=C([H])C(=O)C2=C(O1)C([H])=C(OC([H])([H])C1=C([H])C([H])=C([H])C(=C1[H])C([H])([H])[H])C([H])=C2[H] [H]C1=C([H])C(=O)C2=C(O1)C([H])=C(OC([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H])C([H])=C2[H] [H]C1=C([H])C(=O)C2=C(O1)C([H])=C(OC([H])([H])C1=C([H])C([H])=C([H])C(C#N)=C1[H])C([H])=C2[H] [H]C1=C([H])C(=O)C2=C(O1)C([H])=C(OC([H])([H])C1=C([H])C([H])=C(C#N)C([H])=C1[H])C([H])=C2[H] [H]C1=C([H])C(=O)C2=C(O1)C([H])=C(OC([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C(F)(F)F)C([H])=C2[H] [H]C1=C([H])C(=O)C2=C(O1)C([H])=C(OC([H])([H])C([H])([H])C1=C([H])C([H])=C(Br)C([H])=C1[H])C([H])=C2[H] [H]N1C([H])=C(\C([H])=C2\N(\C(=N\C([H])([H])[H])N([H])C2=O)C([H])([H])[H])C2=C1C([H])=C([H])C([H])=C2Br [H]N1C([H])=C(\C([H])=C2/N([H])C(=S)N([H])C2=O)C2=C1C([H])=C(Br)C([H])=C2[H] [H]N1C([H])=C(\C([H])=C2\N(\C(=N\C([H])([H])[H])N(C2=O)C([H])([H])[H])C([H])([H])[H])C2=C1C(Br)=C([H])C([H])=C2[H] [H]N=C1N([H])\C(=C(\[H])C2=C([H])N([H])C3=C2C([H])=C([H])C([H])=C3[H])C(=O)N1C([H])([H])[H] [H]N=C1N([H])C(=O)\C(=C(\[H])C2=C([H])N([H])C3=C2C([H])=C([H])C([H])=C3Br)N1C([H])([H])[H] [H]N=C1N([H])C(=O)\C(=C(\[H])C2=C([H])N([H])C3=C2C([H])=C([H])C(Br)=C3[H])N1C([H])([H])[H] [H]N=C1N([H])C(=O)\C(=C(\[H])C2=C([H])N([H])C3=C2C([H])=C(Br)C([H])=C3[H])N1C([H])([H])[H] [H]N=C1N([H])C(=O)\C(N1[H])=C(/[H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2Br [H]N=C1N([H])C(=O)\C(N1[H])=C(/[H])C1=C([H])N([H])C2=C1C([H])=C(Br)C([H])=C2[H] [H]N=C1N([H])C(=O)\C(N1[H])=C(/[H])C1=C([H])N([H])C2=C1C(Br)=C([H])C([H])=C2[H] [H]N1C([H])=C(\C([H])=C2/N([H])C(SC([H])([H])[H])=NC2=O)C2=C1C(Br)=C([H])C([H])=C2[H] [H]N1C([H])=C(\C([H])=C2/N([H])\C(=N\C([H])([H])[H])N([H])C2=O)C2=C1C([H])=C([H])C([H])=C2Br [H]N1C([H])=C(\C([H])=C2/N([H])\C(=N\C([H])([H])[H])N([H])C2=O)C2=C1C([H])=C([H])C(Br)=C2[H] [H]N1C([H])=C(\C([H])=C2/N([H])C(=S)N([H])C2=O)C2=C1C([H])=C([H])C([H])=C2Br [H]N1C([H])=C(\C([H])=C2/N([H])C(=S)N([H])C2=O)C2=C1C([H])=C([H])C(Br)=C2[H] [H]N1C([H])=C(\C([H])=C2/N([H])C(=S)N([H])C2=O)C2=C1C(Br)=C([H])C([H])=C2[H] [H]N1C([H])=C(\C([H])=C2/N([H])\C(=N\C([H])([H])[H])N([H])C2=O)C2=C1C(Br)=C([H])C([H])=C2[H] [H]N1C([H])=C(\C([H])=C2/N([H])\C(=N\C([H])([H])[H])N([H])C2=O)C2=C1C([H])=C(Br)C([H])=C2[H] [H]N1C([H])=C(\C([H])=C2/N([H])C(SC([H])([H])[H])=NC2=O)C2=C1C([H])=C(Br)C([H])=C2[H] [H]N1C([H])=C(\C([H])=C2/N([H])C(SC([H])([H])[H])=NC2=O)C2=C1C([H])=C([H])C(Br)=C2[H] [H]N1C([H])=C(\C([H])=C2/N([H])C(SC([H])([H])[H])=NC2=O)C2=C1C([H])=C([H])C([H])=C2Br [H]N1C([H])=C(\C([H])=C2/N=C(SC([H])([H])[H])N([H])C2=O)C2=C1C([H])=C([H])C([H])=C2[H] [H]N1C([H])=C(\C([H])=C2\N(\C(=N\C([H])([H])[H])N(C2=O)C([H])([H])[H])C([H])([H])[H])C2=C1C([H])=C([H])C(Br)=C2[H] [H]N1C([H])=C(\C([H])=C2\N(\C(=N\C([H])([H])[H])N(C2=O)C([H])([H])[H])C([H])([H])[H])C2=C1C([H])=C(Br)C([H])=C2[H] [H]N1C([H])=C(\C([H])=C2\N(\C(=N\C([H])([H])[H])N(C2=O)C([H])([H])[H])C([H])([H])[H])C2=C1C([H])=C([H])C([H])=C2Br [H]N1C([H])=C(\C([H])=C2\N(\C(=N\C([H])([H])[H])N(C2=O)C([H])([H])[H])C([H])([H])[H])C2=C([H])C([H])=C([H])C([H])=C12 [H]N1C([H])=C(\C([H])=C2/N([H])\C(=N\C([H])([H])[H])N(C2=O)C([H])([H])[H])C2=C1C(Br)=C([H])C([H])=C2[H] [H]N1C([H])=C(\C([H])=C2/N([H])\C(=N\C([H])([H])[H])N(C2=O)C([H])([H])[H])C2=C1C([H])=C(Br)C([H])=C2[H] [H]N1C([H])=C(\C([H])=C2/N([H])\C(=N\C([H])([H])[H])N(C2=O)C([H])([H])[H])C2=C1C([H])=C([H])C([H])=C2[H] [H]N1C([H])=C(\C([H])=C2/N([H])\C(=N\C([H])([H])[H])N(C2=O)C([H])([H])[H])C2=C1C([H])=C([H])C([H])=C2Br [H]N=C1N([H])C(=O)\C(N1[H])=C(/[H])C1=C([H])N([H])C2=C1C([H])=C([H])C(Br)=C2[H] [H]N1C([H])=C(\C([H])=C2/N([H])\C(=N\C([H])([H])[H])N(C2=O)C([H])([H])[H])C2=C1C([H])=C([H])C(Br)=C2[H] [H]N=C1N(C(=O)\C(=C(\[H])C2=C([H])N([H])C3=C2C([H])=C([H])C([H])=C3Br)N1C([H])([H])[H])C([H])([H])[H] [H]N=C1N(C(=O)\C(=C(\[H])C2=C([H])N([H])C3=C([H])C(Br)=C([H])C([H])=C23)N1C([H])([H])[H])C([H])([H])[H] [H]N=C1N(C(=O)\C(=C(\[H])C2=C([H])N([H])C3=C2C([H])=C(Br)C([H])=C3[H])N1C([H])([H])[H])C([H])([H])[H] [H]N=C1N(C(=O)\C(=C(\[H])C2=C([H])N([H])C3=C2C(Br)=C([H])C([H])=C3[H])N1C([H])([H])[H])C([H])([H])[H] [H]N1C([H])=C(\C([H])=C2\N(\C(=N\C([H])([H])[H])N([H])C2=O)C([H])([H])[H])C2=C1C(Br)=C([H])C([H])=C2[H] [H]N=C1N(C(=O)\C(=C(\[H])C2=C([H])N([H])C3=C([H])C([H])=C([H])C([H])=C23)N1C([H])([H])[H])C([H])([H])[H] [H]N1C([H])=C(\C([H])=C2\N(\C(=N\C([H])([H])[H])N([H])C2=O)C([H])([H])[H])C2=C1C([H])=C(Br)C([H])=C2[H] [H]N1C([H])=C(\C([H])=C2\N(\C(=N\C([H])([H])[H])N([H])C2=O)C([H])([H])[H])C2=C1C([H])=C([H])C(Br)=C2[H] [H]N1C([H])=C(\C([H])=C2\N(\C(=N\C([H])([H])[H])N([H])C2=O)C([H])([H])[H])C2=C([H])C([H])=C([H])C([H])=C12 [H]N=C1N([H])\C(=C(\[H])C2=C([H])N([H])C3=C2C([H])=C([H])C([H])=C3Br)C(=O)N1C([H])([H])[H] [H]N=C1N([H])\C(=C(\[H])C2=C([H])N([H])C3=C2C([H])=C([H])C(Br)=C3[H])C(=O)N1C([H])([H])[H] [H]N=C1N([H])\C(=C(\[H])C2=C([H])N([H])C3=C2C([H])=C(Br)C([H])=C3[H])C(=O)N1C([H])([H])[H] [H]N=C1N([H])\C(=C(\[H])C2=C([H])N([H])C3=C2C(Br)=C([H])C([H])=C3[H])C(=O)N1C([H])([H])[H] [H]\C(=C1\SC(=O)N(C1=O)C([H])([H])C([H])([H])C#N)C1=C([H])C([H])=C([H])C([H])=C1[H] [H]N([H])C([H])([H])C([H])([H])N1C(=O)S\C(=C(\[H])C2=C([H])C([H])=C(OC([H])([H])C([H])([H])[H])C([H])=C2[H])C1=O [H]N([H])C([H])([H])C([H])([H])N1C(=O)S\C(=C(\[H])C2=C([H])C([H])=C(C([H])=C2[H])N(C([H])([H])[H])C([H])([H])[H])C1=O [H]\C(=C1/SC(=S)N(C1=O)C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H] [H]OC(=O)C1=C([H])OC2=C([H])C([H])=C(OC([H])([H])C3=C([H])C(Br)=C([H])C([H])=C3[H])C([H])=C2C1=O [H]C(=O)C1=C([H])OC2=C([H])C([H])=C(OC([H])([H])C3=C([H])C(Br)=C([H])C([H])=C3[H])C([H])=C2C1=O [H]C1=C([H])C(=C([H])C(Br)=C1[H])C([H])([H])OC1=C([H])C([H])=C2OC([H])=C(C(=O)OC([H])([H])[H])C(=O)C2=C1[H] [H]OC1=C([H])C([H])=C(OC([H])([H])C2=C([H])C([H])=C(Br)C([H])=C2[H])C([H])=C1C(=O)C([H])([H])[H] [H]O[C@@]1([H])OC2=C([H])C([H])=C(OC([H])([H])C3=C([H])C(Br)=C([H])C([H])=C3[H])C([H])=C2C(=O)C1([H])[H] [H]OC1=C([H])C(OC([H])([H])C2=C([H])C([H])=C(Br)C([H])=C2[H])=C([H])C([H])=C1C(=O)C([H])([H])[H] [H]N(\N=C(/[H])C1=C([H])C([H])=C([H])C([H])=C1OC([H])([H])[H])C1=NC2=C([H])C([H])=C([H])C([H])=C2N=C1C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H] [H]N(\N=C(/[H])C1=C([H])C([H])=C(OC([H])([H])[H])C(OC([H])([H])[H])=C1[H])C1=NC2=C([H])C([H])=C([H])C([H])=C2N=C1C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H] C(C1=CC=CC=C1)C1=NC2=CC=CC=C2N=C1N\N=C\C1=CC=C2OCOC2=C1 [H]N(\N=C(\C1=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C(OC([H])([H])[H])=C1[H])C([H])([H])[H])C1=NC2=C([H])C([H])=C([H])C([H])=C2N=C1C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H] [H]N(\N=C(\C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])C([H])([H])[H])C1=NC2=C([H])C([H])=C([H])C([H])=C2N=C1C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H] [H]N(\N=C(/[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C1=NC2=C([H])C([H])=C([H])C([H])=C2N=C1C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H] ClC1=CC=C(\C=N\NC2=NC3=CC=CC=C3N=C2CC2=CC=CC=C2)C=C1 ClC1=CC=CC=C1\C=N\NC1=NC2=CC=CC=C2N=C1CC1=CC=CC=C1 COC1=CC=C(\C=N\NC2=NC3=CC=CC=C3N=C2CC2=CC=CC=C2)C=C1 [H]N(\N=C(\C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H])C1=NC2=C([H])C([H])=C([H])C([H])=C2N=C1C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H] [H]OC1=C([H])C([H])=C(C([H])=C1[H])C(=N\N([H])C1=NC2=C([H])C([H])=C([H])C([H])=C2N=C1C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])\C([H])([H])[H] C\C(=N/NC1=NC2=CC=CC=C2N=C1CC1=CC=CC=C1)C1=CC=C(C=C1)[N+]([O-])=O [H]OC1=C([H])C([H])=C(\C([H])=N\N([H])C2=NC3=C([H])C([H])=C([H])C([H])=C3N=C2C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])=C1[H] [H]N(\N=C(/[H])C1=C([H])C([H])=C(C([H])=C1[H])N(C([H])([H])[H])C([H])([H])[H])C1=NC2=C([H])C([H])=C([H])C([H])=C2N=C1C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H] [H]N(\N=C(\C1=C([H])C([H])=C([H])C([H])=N1)C([H])([H])[H])C1=NC2=C([H])C([H])=C([H])C([H])=C2N=C1C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H] [H]N(\N=C(\C1=C([H])C([H])=C([H])S1)C([H])([H])[H])C1=NC2=C([H])C([H])=C([H])C([H])=C2N=C1C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H] [H]N(\N=C(\C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H])C([H])([H])[H])C1=NC2=C([H])C([H])=C([H])C([H])=C2N=C1C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H] [H]N([H])C1=C([H])C([H])=C(C([H])=C1[H])C(=N\N([H])C1=NC2=C([H])C([H])=C([H])C([H])=C2N=C1C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])\C([H])([H])[H] [H]N(\N=C(/[H])C1=C([H])C([H])=C(C([H])=C1[H])[N+]([O-])=O)C1=NC2=C([H])C([H])=C([H])C([H])=C2N=C1C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H] BrC1=CC(\C=N\NC2=NC3=CC=CC=C3N=C2CC2=CC=CC=C2)=CC=C1 [H]N(\N=C(/[H])C1=C(C([H])=C([H])S1)C([H])([H])[H])C1=NC2=C([H])C([H])=C([H])C([H])=C2N=C1C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H] [H]C([H])=NN([H])C1=NC2=C([H])C([H])=C([H])C([H])=C2N=C1C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H] [H]C1=C([H])C([H])=C(C([H])=C1[H])C1=NN=C2N1C1=C([H])C([H])=C([H])C([H])=C1N=C2C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H] ClC1=CC=CC=C1C1=NN=C2N1C1=CC=CC=C1N=C2CC1=CC=CC=C1 COC1=CC=C(C=C1OC)C1=NN=C2N1C1=CC=CC=C1N=C2C(=O)C1=CC=CC=C1 [H]C1=C([H])C([H])=C(C([H])=C1[H])C(=O)C1=NC2=C([H])C([H])=C([H])C([H])=C2N2C(=NN=C12)C1=C([H])C([H])=C([H])C([H])=C1[H] [H]C1=C([H])C([H])=C(C([H])=C1[H])C(=O)C1=NC2=C([H])C([H])=C([H])C([H])=C2N2C1=NN=C2C1=C([H])C([H])=C([H])C([H])=C1Cl COC1=CC=C(C=C1)C1=NN=C2N1C1=CC=CC=C1N=C2C(=O)C1=CC=CC=C1 [H]C1=C([H])C([H])=C(C([H])=C1[H])C(=O)C1=NC2=C([H])C([H])=C([H])C([H])=C2N2C(=NN=C12)C1=C([H])C([H])=C(C([H])=C1[H])N(C([H])([H])[H])C([H])([H])[H] CN(C)C1=C(Br)C=C(C=C1)C1=NN=C2N1C1=CC=CC=C1N=C2C(=O)C1=CC=CC=C1 [H]C1=C([H])C([H])=C(C([H])=C1[H])C(=O)C1=NC2=C([H])C([H])=C([H])C([H])=C2N2C(=NN=C12)C1=C([H])C([H])=C(C([H])=C1[H])[N+]([O-])=O [H]C1=NN=C2N1C1=C([H])C([H])=C([H])C([H])=C1N=C2C(=O)C1=C([H])C([H])=C([H])C([H])=C1[H] C(C1=CC=CC=C1)C1=NC2=CC=CC=C2N2C=NN=C12 [H]N(\N=C(/C1=NC([H])=C([H])S1)C([H])([H])[H])C1=NC(=C([H])S1)C1=C([H])C([H])=C(C#N)C([H])=C1[H] [H]N(\N=C(/C1=C([H])C([H])=C([H])C([H])=N1)C([H])([H])[H])C1=NC(=C([H])S1)C1=C([H])C([H])=C(C#N)C([H])=C1[H] [H]N(\N=C(/C1=NC([H])=C([H])S1)C([H])([H])[H])C1=NC(=C([H])S1)C1=C([H])C([H])=C(C([H])=C1[H])[N+]([O-])=O [H]N(\N=C(/C1=C([H])C([H])=C([H])O1)C([H])([H])[H])C1=NC(=C([H])S1)C1=C([H])C([H])=C(F)C([H])=C1[H] [H]N(\N=C(/C1=NC([H])=C([H])S1)C([H])([H])[H])C1=NC(=C([H])S1)C1=C([H])C([H])=C(F)C([H])=C1[H] [H]N(\N=C(/C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H])C1=NC(=C([H])S1)C1=C([H])C([H])=C(F)C([H])=C1[H] [H]N(\N=C(\[H])C1=C([H])C([H])=C([H])O1)C1=NC(=C([H])S1)C1=C(F)C([H])=C(F)C([H])=C1[H] [H]N(\N=C(/C1=NC([H])=C([H])S1)C([H])([H])[H])C1=NC(=C([H])S1)C1=C(F)C([H])=C(F)C([H])=C1[H] [H]N(\N=C(/C1=C([H])C([H])=C([H])C([H])=N1)C([H])([H])[H])C1=NC(=C([H])S1)C1=C(F)C([H])=C(F)C([H])=C1[H] [H]N1C(=O)C2=C([H])C([H])=C(SC([H])([H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])=C2C1=O [H]N1C(=O)C2=C([H])C([H])=C(SC3([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C3([H])[H])C([H])=C2C1=O [H]N1C(=O)C2=C([H])C([H])=C(SC([H])([H])C([H])([H])C3=C([H])C([H])=C([H])C([H])=C3[H])C([H])=C2C1=O [H]N1C(=O)C2=C([H])C([H])=C(SC3=C([H])C([H])=C(Br)C([H])=C3[H])C([H])=C2C1=O [H]N1C(=O)C2=C([H])C([H])=C(SC3=C([H])C([H])=C(Cl)C([H])=C3[H])C([H])=C2C1=O [H]N1C(=O)C2=C([H])C([H])=C(SC3=C([H])C([H])=C([H])C([H])=C3[H])C([H])=C2C1=O [H]N1C(=O)C2=C([H])C([H])=C(SC([H])([H])C3=C([H])C([H])=C(OC([H])([H])[H])C([H])=C3[H])C([H])=C2C1=O [H]N1C(=O)C2=C([H])C([H])=C(SC([H])([H])C3=C([H])C([H])=C(F)C([H])=C3[H])C([H])=C2C1=O [H]N1C(=O)C2=C([H])C([H])=C(SC([H])([H])C3=C([H])C([H])=C(Br)C([H])=C3[H])C([H])=C2C1=O [H]N1C(=O)C2=C([H])C([H])=C(SC([H])([H])C3=C([H])C([H])=C(Cl)C([H])=C3[H])C([H])=C2C1=O [H]N1C(=O)C2=C([H])C([H])=C(SC([H])([H])C3=C([H])C([H])=C([H])C([H])=C3[H])C([H])=C2C1=O [H]OC1=C([H])C(OC([H])([H])C([H])=C(C([H])([H])[H])C([H])([H])[H])=C([H])C([H])=C1C1=NN(C(=O)C([H])([H])[H])[C@]([H])(C2=C([H])C([H])=C(OC([H])([H])C3=C([H])C([H])=C([H])C([H])=C3[H])C([H])=C2[H])C1([H])[H] [H]C#CC([H])([H])N([H])[C@@]1([H])C2=C([H])C([H])=C([H])C([H])=C2C([H])([H])[C@]1([H])[18F] CN1C(COC2=CC=CC(=C2)C(F)(F)F)=NC2=C1C(=O)N(C)C(=O)N2C CN1C(COC2=CC=C(F)C=C2)=NC2=C1C(=O)N(C)C(=O)N2C [H]OC(=O)C1=C([H])C2=C([H])C(Br)=C([H])C([H])=C2C([H])([H])C1=O [H]C1=C(C([H])=C2C([H])=C(C(=O)OC([H])([H])C([H])([H])[H])C(=O)C([H])([H])C2=C1[H])C([H])([H])[H] [H]OC(=O)C1=C([H])C2=C([H])C(=C([H])C([H])=C2C([H])([H])C1=O)[N+]([O-])=O [H]C1=C(C([H])=C2C([H])=C(C(Cl)=O)C(=O)C([H])([H])C2=C1[H])C([H])([H])[H] [H]C1=C(C([H])=C2C([H])=C(C(Cl)=O)C(=O)C([H])([H])C2=C1[H])[N+]([O-])=O [H]C1=C(Br)C([H])=C2C([H])=C(C(Cl)=O)C(=O)C([H])([H])C2=C1[H] [H]OC(=O)C1=C([H])C2=C([H])C(Cl)=C([H])C([H])=C2C([H])([H])C1=O [H]C1=C([H])C([H])=C2C(=C1[H])C([H])=C(C(=O)OC([H])([H])C([H])([H])[H])C(=O)C2([H])[H] [H]C1=C(Cl)C([H])=C2C([H])=C(C(Cl)=O)C(=O)C([H])([H])C2=C1[H] [H]C1=C(C([H])=C2C([H])=C(C(=O)OC([H])([H])C([H])([H])[H])C(=O)C([H])([H])C2=C1[H])[N+]([O-])=O [H]C1=C(Br)C([H])=C2C([H])=C(C(=O)OC([H])([H])C([H])([H])[H])C(=O)C([H])([H])C2=C1[H] [H]C1=C(Cl)C([H])=C2C([H])=C(C(=O)OC([H])([H])C([H])([H])[H])C(=O)C([H])([H])C2=C1[H] [H]C1=C([H])C([H])=C2C(=C1[H])C([H])=C(C(Cl)=O)C(=O)C2([H])[H] [H]N(C([H])([H])C(=O)N1C([H])([H])C([H])([H])N(C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H])[C@@]1([H])C([H])([H])[C@]1([H])C1=C([H])C([H])=C([H])C([H])=C1[H] [H]N(C(=O)C([H])([H])N([H])[C@@]1([H])C([H])([H])[C@]1([H])C1=C([H])C([H])=C(OC([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])=C1[H])C1([H])C([H])([H])C1([H])[H] [H]N(C([H])([H])C(=O)N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H])[C@@]1([H])C([H])([H])[C@]1([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C(=C([H])C([H])=C1[H])C(F)(F)F [H]N(C([H])([H])C(=O)N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H])[C@@]1([H])C([H])([H])[C@]1([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C(Cl)=C([H])C(Cl)=C1[H] [H]N(C([H])([H])C(=O)N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H])[C@@]1([H])C([H])([H])[C@]1([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])N=C(OC([H])([H])[H])C([H])=C1[H] [H]N(C([H])([H])C(=O)N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H])[C@@]1([H])C([H])([H])[C@]1([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C([H])N=C1OC([H])([H])[H] C[C@H](CC1=CC=C(OCCCCCCCCNC2=C3C=CC(Cl)=CC3=NC3=C2CCCC3)C=C1)N(C)CC#C C[C@H](CC1=CC=C(OCCCCCCNC2=C3C=CC(Cl)=CC3=NC3=C2CCCC3)C=C1)N(C)CC#C C[C@H](CC1=CC=C(OCCCCCNC2=C3C=CC(Cl)=CC3=NC3=C2CCCC3)C=C1)N(C)CC#C C[C@H](CC1=CC=C(OCCCNC2=C3C=CC(Cl)=CC3=NC3=C2CCCC3)C=C1)N(C)CC#C C[C@H](CC1=CC=C(OCCCCCCCCCCNC2=C3C=CC=CC3=NC3=C2CCCC3)C=C1)N(C)CC#C C[C@H](CC1=CC=C(OCCCCCCNC2=C3C=CC=CC3=NC3=C2CCCC3)C=C1)N(C)CC#C C[C@H](CC1=CC=C(OCCCCCNC2=C3C=CC=CC3=NC3=C2CCCC3)C=C1)N(C)CC#C C[C@H](CC1=CC=C(OCCCCNC2=C3C=CC=CC3=NC3=C2CCCC3)C=C1)N(C)CC#C C[C@H](CC1=CC=C(OCCNC2=C3C=CC=CC3=NC3=C2CCCC3)C=C1)N(C)CC#C CN1C(=CC2=C1C(=O)N(C)C(=O)N2C)N1C=C(N=N1)C1=CC=C(Cl)C=C1 CN1C(OCC2=CC=C(Cl)C=C2)=CC2=C1C(=O)N(C)C(=O)N2C CN1C(=CC2=C1C(=O)N(C)C(=O)N2C)C#CC1=CC=C(Cl)C=C1 CN1C(\C=C\C2=CC=C(Br)C=C2)=CC2=C1C(=O)N(C)C(=O)N2C CCCOC1=CC=C(\C=C\C2=CC3=C(N2C)C(=O)N(C)C(=O)N3C)C=C1 COC1=CC=C(\C=C\C2=CC3=C(N2C)C(=O)N(C)C(=O)N3C)C=C1 CN1C(\C=C\C2=CC=C(F)C=C2)=CC2=C1C(=O)N(C)C(=O)N2C CN1C(\C=C\C2=CC=CC(=C2)C(F)(F)F)=CC2=C1C(=O)N(C)C(=O)N2C COC1=CC(\C=C\C2=CC3=C(N2C)C(=O)N(C)C(=O)N3C)=CC=C1 CN1C2=C(C=CC(=C2)C2=CC=CC(Cl)=C2)C2=C1C(=O)N(C)C(=O)N2C O\C(\C=C\C1=CC(O)=C(O)C=C1)=C/C(=O)C1=CC=CC=C1O O\C(\C=C\C1=CC=C(O)C=C1)=C/C(=O)C1=CC=CC=C1O COC1=C(O)C=CC(\C=C\C(\O)=C\C(=O)C2=C(OC)C=CC=C2O)=C1 COC1=C(O)C=CC(\C=C\C=C\C(=O)C2=C(O)C=CC=C2O)=C1 COC1=C(O)C=CC(\C=C\C=C\C(=O)C2=C(OC)C=CC=C2O)=C1 COC1=C(O)C=CC(\C=C\C=C\C(=O)C2=CC=CC=C2O)=C1 CC(C)C[C@@H](CF)N(C)CC#C CN(CC#C)[C@H](CF)CC1=CC=CO1 CN(CC#C)[C@H](CF)CC(C)=C