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[H]N(C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C(C([H])=C2C([H])=NC(SC([H])([H])[H])=NC2=N1)C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H]
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[H]N([H])C1=C(C([H])=C([H])C([H])=C1[H])C(=O)C([H])([H])C([H])([H])N([H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C(C([H])=C2C([H])=NC(SC([H])([H])[H])=NC2=N1)C1=C([H])C([H])=C([H])C([H])=C1[H]
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[H]N([H])C1=NON=C1C1=NC2=C([H])N=C([H])C(C(=O)N([H])C([H])([H])C([H])([H])N([H])C([H])([H])[H])=C2N1C([H])([H])C([H])([H])[H]
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[H]N([H])C1=NN=C(S1)C1=C([H])C(C2=C([H])C([H])=C([H])C([H])=C2[H])=C(N=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N([H])C([H])([H])C([H])([H])C(=O)C1=C(N([H])[H])C([H])=C([H])C([H])=C1[H]
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[H]OC(C#CC1=C2N=C(N(C2=C(OC([H])([H])C([H])([H])N([H])[H])C([H])=N1)C([H])([H])C([H])([H])[H])C1=NON=C1N([H])[H])(C([H])([H])[H])C([H])([H])[H]
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[H]N([H])C(=O)C1=C(N([H])C(=O)N([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C2=C(S1)N([H])N=C2C([H])([H])[H]
[H]OC1=C2C([H])=C([H])C([H])=C3C2=NN1C([H])([H])C([H])([H])[N@@]1C([H])([H])[C@@]([H])(OC2=C4N=C3C(O[H])=NC4=C([H])C([H])=C2[H])C([H])([H])[C@@]1([H])C([H])([H])[H]
[H]N([H])C([H])([H])[C@@]([H])(N([H])C(=O)C1=C([H])C([H])=C(S1)C1=NC(=NC([H])=C1[H])N([H])C([H])([H])[H])C([H])([H])C1=C(Cl)C([H])=C(Cl)C([H])=C1[H]
[H]N(C1=C([H])C([H])=C(OC([H])([H])C([H])([H])[H])C([H])=C1[H])C1=C(Cl)C(=O)C2=C(C([H])=NN2[H])C1=O
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[H]N(C(=O)N([H])C([H])([H])[H])C1=NC([H])=C(C([H])=C1[H])C([H])([H])N([H])C1=C(C([H])=NN1C([H])([H])[H])C(=O)N([H])C1=C([H])C([H])=C(SC(F)(F)F)C([H])=C1[H]
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[H]N(C1=C(Cl)C([H])=C2N([H])C(=O)N([H])C3=NC(OC([H])([H])C([H])([H])C([H])([H])C([H])([H])OC2=C1[H])=C(N=C3[H])C#N)C([H])([H])C1=C([H])N=C([H])S1
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[H]N1C(=NN=C1C1([H])C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C(C([H])=C2[H])C2=NC3=NC(=NC([H])=C3C([H])=C2C2=C([H])C([H])=C([H])C([H])=C2[H])N2C([H])([H])C([H])([H])S(=O)(=O)C([H])([H])C2([H])[H])C([H])([H])C1([H])[H])C1=NC([H])=C([H])C([H])=C1[H]
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[H]OC1([H])C([H])([H])C([H])([H])N(C2=NC([H])=C3C([H])=C(C4=C([H])C([H])=C([H])C([H])=C4[H])C(=NC3=N2)C2=C([H])C([H])=C(C([H])=C2[H])C([H])([H])N2C([H])([H])C([H])([H])C([H])(C3=NN=C(N3[H])C3=NC([H])=C([H])C([H])=C3[H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
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[H]N1C(=NN=C1C1([H])C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C(C([H])=C2[H])C2=NC3=C(C([H])=C2C2=C([H])C([H])=C([H])C([H])=C2[H])C(=O)N([H])C([H])=C3[H])C([H])([H])C1([H])[H])C1=C([H])N([H])C(=O)C([H])=C1[H]
[H]N1C(=NN=C1C1([H])C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C(C([H])=C2[H])C2=NC3=C(C([H])=C2C2=C([H])C([H])=C([H])C([H])=C2[H])C(=O)N([H])C([H])=C3[H])C([H])([H])C1([H])[H])C1=NC([H])=C([H])C([H])=N1
[H]N1C(=NN=C1C1([H])C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C(C([H])=C2[H])C2=NC3=C(C([H])=NC(=N3)N3C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C3([H])[H])C([H])=C2C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H])C1=C([H])C([H])=[N+]([O-])C([H])=C1[H]
[H]N1C(=NN=C1C1([H])C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C(C([H])=C2[H])C2=NC3=C(C([H])=NC(=N3)N3C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H])C([H])([H])C3([H])[H])C([H])=C2C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H])C1=C([H])N([H])C(=O)C([H])=C1[H]
[H]OC([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=NC3=C(C([H])=N2)C([H])=C(C2=C([H])C([H])=C([H])C([H])=C2[H])C(=N3)C2=C([H])C([H])=C(C([H])=C2[H])C([H])([H])N2C([H])([H])C([H])([H])C([H])(C3=NN=C(N3[H])C3=C([H])N([H])C(=O)C([H])=C3[H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]N([H])C1=NC([H])=C(C([H])=C1[H])C1=NN=C(N1[H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C(C([H])=C2[H])C2=NC3=C(C([H])=NC(=N3)N3C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H])C([H])([H])C3([H])[H])C([H])=C2C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]OC([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=NC3=C(C([H])=N2)C([H])=C(C2=C([H])C([H])=C([H])C([H])=C2[H])C(=N3)C2=C([H])C([H])=C(C([H])=C2[H])C([H])([H])N2C([H])([H])C([H])([H])C([H])(C3=NN=C(N3[H])C3=C([H])N=C(N([H])[H])C([H])=C3[H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]N([H])C1=NC([H])=C(C([H])=C1[H])C1=NN=C(N1[H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C(C([H])=C2[H])C2=NC3=C(C([H])=NC(=N3)N3C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C3([H])[H])C([H])=C2C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N1C(=NN=C1C1([H])C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C(C([H])=C2[H])C2=NC3=C(C([H])=NC(=N3)N3C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H])C([H])([H])C3([H])[H])C([H])=C2C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H])C1=NC([H])=C([H])C([H])=N1
[H]OC([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C2=NC3=C(C([H])=N2)C([H])=C(C2=C([H])C([H])=C([H])C([H])=C2[H])C(=N3)C2=C([H])C([H])=C(C([H])=C2[H])C([H])([H])N2C([H])([H])C([H])([H])C([H])(C3=NN=C(N3[H])C3=NC([H])=C([H])C([H])=N3)C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]N1C(=NN=C1C1([H])C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C(C([H])=C2[H])C2=NC3=C(C([H])=NC(=N3)N3C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C3([H])[H])C([H])=C2C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H])C1=NC([H])=C([H])C([H])=N1
[H]N([H])C1=NC([H])=C([H])C(=N1)C1=C([H])C2=C(N=C(N2[H])[C@@]2([H])C([H])([H])OC3=C(C([H])=C(OC([H])([H])[H])C([H])=C3[H])C2([H])[H])C(F)=C1[H]
[H]OC([H])([H])C([H])([H])N([H])C([H])([H])C1=NN=C2N1C([H])=C([H])C1=C2C([H])=C(C2=C([H])C([H])=C([H])C([H])=C2[H])C(=N1)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1C([H])([H])C([H])([H])C([H])(C2=NN([H])C(=N2)C2=NC([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N1N=C(N=C1C1=NC([H])=C([H])C([H])=C1[H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C(C([H])=C2[H])C2=NC3=C(C([H])=C2C2=C([H])C([H])=C([H])C([H])=C2[H])C2=NN=C(N2C([H])=C3[H])C([H])([H])N2C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]N1N=C(N=C1C1=NC([H])=C([H])C([H])=C1[H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C(C([H])=C2[H])C2=NC3=C(C([H])=C2C2=C([H])C([H])=C([H])C([H])=C2[H])C2=NN=C(N2C([H])=C3[H])C([H])([H])Cl)C([H])([H])C1([H])[H]
[H]N1N=C(N=C1C1=NC([H])=C([H])C([H])=C1[H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C(C([H])=C2[H])C2=NC3=C(C([H])=C2C2=C([H])C([H])=C([H])C([H])=C2[H])C2=NN=C(N2C([H])=C3[H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N([H])C1=NN=C2N1C([H])=C([H])C1=C2C([H])=C(C2=C([H])C([H])=C([H])C([H])=C2[H])C(=N1)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1C([H])([H])C([H])([H])C([H])(N2C([H])=NC(=C2[H])C2=NC([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N1N=C(N=C1C1=NC([H])=C([H])C([H])=C1[H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C(C([H])=C2[H])C2=NC3=C(C([H])=C2C2=C([H])C([H])=C([H])C([H])=C2[H])C2=NN=C([H])N2C([H])=C3[H])C([H])([H])C1([H])[H]
[H]N([H])C(=O)N([H])C1=NN=C2N1C([H])=C([H])C1=C2C([H])=C(C2=C([H])C([H])=C([H])C([H])=C2[H])C(=N1)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1C([H])([H])C([H])([H])C([H])(C2=NN([H])C(=N2)C2=NC([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]SC1=NN=C2N1C([H])=C([H])C1=C2C([H])=C(C2=C([H])C([H])=C([H])C([H])=C2[H])C(=N1)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1C([H])([H])C([H])([H])C([H])(C2=NN([H])C(=N2)C2=NC([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]OC1=NN=C2N1C([H])=C([H])C1=C2C([H])=C(C2=C([H])C([H])=C([H])C([H])=C2[H])C(=N1)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1C([H])([H])C([H])([H])C([H])(C2=NN([H])C(=N2)C2=NC([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N([H])C1=NN=C2N1C([H])=C([H])C1=C2C([H])=C(C2=C([H])C([H])=C([H])C([H])=C2[H])C(=N1)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1C([H])([H])C([H])([H])C([H])(C2=NN([H])C(=N2)C2=NC([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N([H])C([H])([H])[C@]([H])(N([H])C(=O)C1=C([H])C([H])=C(S1)C1=C2C([H])=C([H])N([H])C2=NC([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N([H])C([H])([H])[C@]([H])(N([H])C(=O)C1=C([H])C([H])=C(S1)C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=N2)C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N([H])C([H])([H])[C@]([H])(N([H])C(=O)C1=C([H])C(=C([H])S1)C1=C2C([H])=C([H])N([H])C2=NC([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N([H])C([H])([H])[C@]([H])(N([H])C(=O)C1=C([H])C(=C([H])S1)C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=N2)C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N([H])C([H])([H])[C@]([H])(N([H])C([H])([H])C1=C([H])C([H])=C(S1)C1=C2C([H])=C([H])N([H])C2=NC([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N([H])C([H])([H])[C@@]([H])(N([H])C(=O)C1=C([H])C(Br)=C(S1)C1=C2C([H])=C([H])N([H])C2=NC([H])=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1C(F)(F)F
[H]N([H])C([H])([H])[C@@]([H])(N([H])C(=O)C1=C([H])C(Br)=C(S1)C1=C2C([H])=C([H])N([H])C2=NC([H])=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C(=C1[H])C(F)(F)F
[H]N([H])C([H])([H])[C@@]([H])(N([H])C(=O)C1=C([H])C(Br)=C(S1)C1=C2C([H])=C([H])N([H])C2=NC([H])=C1[H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C(F)(F)F
[H]N([H])C([H])([H])[C@]([H])(N([H])C(=O)C1=C([H])C(Br)=C(S1)C1=C2C([H])=C([H])N([H])C2=NC([H])=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N([H])C([H])([H])[C@@]([H])(N([H])C(=O)C1=C([H])C(Br)=C(S1)C1=C2C([H])=C([H])N([H])C2=NC([H])=C1[H])C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N([H])C([H])([H])[C@@]([H])(N([H])C(=O)C1=C([H])C(Br)=C(S1)C1=C2C([H])=C([H])N([H])C2=NC([H])=C1[H])C([H])([H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]N([H])C([H])([H])[C@@]([H])(N([H])C(=O)C1=C([H])C(Br)=C(S1)C1=C2C([H])=C([H])N([H])C2=NC([H])=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C(F)=C1[H]
[H]N([H])C([H])([H])[C@@]([H])(N([H])C(=O)C1=C([H])C(Br)=C(S1)C1=C2C([H])=C([H])N([H])C2=NC([H])=C1[H])C([H])([H])C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]N([H])C([H])([H])[C@@]([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])N([H])C1=C([H])C([H])=C(S1)C1=C2C([H])=C([H])N([H])C2=NC([H])=C1[H]
[H]N([H])C([H])([H])[C@]([H])(C(=O)N([H])C1=C([H])C([H])=C(S1)C1=C2C([H])=C([H])N([H])C2=NC([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N([H])C([H])([H])[C@]([H])(C(=O)N([H])C1=C([H])C(Br)=C(S1)C1=C2C([H])=C([H])N([H])C2=NC([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N([H])C([H])([H])[C@]([H])(N([H])C(=O)C1=C([H])C(Br)=C(S1)C1=C2C([H])=C([H])N([H])C2=NC([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N([H])C([H])([H])[C@]([H])(N([H])C(=O)C1=C([H])C(=C(S1)C1=C2C([H])=C([H])N([H])C2=NC([H])=C1[H])C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N([H])C([H])([H])[C@]([H])(N([H])C(=O)C1=C([H])C(=C(S1)C1=C2C([H])=C([H])N([H])C2=NC([H])=C1[H])C1([H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N([H])C([H])([H])[C@]([H])(N([H])C(=O)C1=C([H])C(=C(S1)C1=C2C([H])=C([H])N([H])C2=NC([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N([H])C([H])([H])[C@]([H])(N([H])C(=O)C1=C([H])C(=C(S1)C1=C2C([H])=C([H])N([H])C2=NC([H])=C1[H])C1=C([H])N=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)C1=C([H])C(Br)=C(S1)C1=C2C([H])=C([H])N([H])C2=NC([H])=C1[H])[C@@]([H])(C([H])([H])N([H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)C1=C([H])C(Br)=C(S1)C1=C2C([H])=C([H])N([H])C2=NC([H])=C1[H])[C@@]([H])(C([H])([H])N([H])C([H])([H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C1=NC(N([H])C2=C([H])C([H])=C([H])C3=C2C(=O)N([H])C3([H])[H])=C2C([H])=C([H])N([H])C2=N1)C1=C(OC([H])([H])[H])C([H])=C2C(=C1[H])N(C(=O)C([H])([H])N(C([H])([H])[H])C([H])([H])[H])C([H])([H])C2([H])[H]
[H]N([H])C([H])([H])[C@]([H])(N([H])C(=O)C1=C([H])C(=C(S1)C1=C2C([H])=C([H])N([H])C2=NC([H])=C1[H])C1=C([H])N([H])N=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N([H])C([H])([H])C([H])([H])N([H])C(=O)C1=C([H])C(Br)=C(S1)C1=C2C([H])=C([H])N([H])C2=NC([H])=C1[H]
[H]N([H])C([H])([H])[C@@]([H])(N([H])C(=O)C1=C([H])C(Br)=C(S1)C1=C2C([H])=C([H])N([H])C2=NC([H])=C1[H])C([H])([H])C1=C([H])C([H])=NC([H])=C1[H]
[H]N([H])C([H])([H])[C@@]([H])(N([H])C(=O)C1=C([H])C(Br)=C(S1)C1=C2C([H])=C([H])N([H])C2=NC([H])=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1F
[H]N=C(SC([H])([H])C([H])([H])C([H])([H])N1C(=O)C2=C(N3C(=C([H])C4=C([H])C([H])=C([H])C([H])=C34)C3=C([H])C([H])=C([H])C4=C3N2C([H])=C4[H])C1=O)N([H])[H]
[H]N([H])[C@@]([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])N([H])C(=O)C1=C([H])C(Br)=C(S1)C1=C2C([H])=C([H])N([H])C2=NC([H])=C1[H]
[H]N(C(=O)C1=C([H])C(Br)=C(S1)C1=C2C([H])=C([H])N([H])C2=NC([H])=C1[H])[C@@]([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])N([H])C([H])([H])[H]
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[H]OC1=C([H])C([H])=C(C([H])=C1[H])C1=C(C([H])=C(OC([H])([H])[C@@]([H])(N([H])[H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])=N1)C1=C([H])C2=C(N([H])N=C2C([H])([H])[H])C([H])=C1[H]
[H]OC1=C([H])C([H])=C([H])C(=C1[H])C1=C(C([H])=C(OC([H])([H])[C@@]([H])(N([H])[H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])=N1)C1=C([H])C2=C(N([H])N=C2C([H])([H])[H])C([H])=C1[H]
[H]OC1=C([H])C([H])=C([H])C([H])=C1C1=C(C([H])=C(OC([H])([H])[C@@]([H])(N([H])[H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])=N1)C1=C([H])C2=C(N([H])N=C2C([H])([H])[H])C([H])=C1[H]
[H]N([H])[C@]([H])(C([H])([H])OC1=C([H])C(=C(N=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C2=C(N([H])N=C2C([H])([H])[H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N([H])[C@]([H])(C([H])([H])OC1=C([H])C(=C(N=C1[H])C1=C([H])OC([H])=C1[H])C1=C([H])C2=C(N([H])N=C2C([H])([H])[H])C([H])=C1[H])C([H])([H])C1=C([H])N([H])C2=C1C([H])=NC([H])=C2[H]
[H]N([H])[C@]([H])(C([H])([H])OC1=C([H])C(=C(N=C1[H])C1=C(OC([H])=C1[H])C([H])([H])[H])C1=C([H])C2=C(N([H])N=C2C([H])([H])[H])C([H])=C1[H])C([H])([H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H]
[H]OC1=C([H])C([H])=C(F)C([H])=C1C1=C(C([H])=C(OC([H])([H])[C@@]([H])(N([H])[H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])=N1)C1=C([H])C2=C(N([H])N=C2C([H])([H])[H])C([H])=C1[H]
[H]N([H])[C@]([H])(C([H])([H])OC1=C([H])C(=C(N=C1[H])C1=C([H])C([H])=C([H])O1)C1=C([H])C2=C(N([H])N=C2C([H])([H])[H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC([H])([H])C([H])([H])C#CC1=C(C([H])=C(OC([H])([H])[C@@]([H])(N([H])[H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])=N1)C1=C([H])C2=C(N([H])N=C2C([H])([H])[H])C([H])=C1[H]
[H]N([H])[C@]([H])(C([H])([H])OC1=C([H])C(=C(N=C1[H])C1=C([H])C([H])=C([H])N1[H])C1=C([H])C2=C(N([H])N=C2C([H])([H])[H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N([H])[C@]([H])(C([H])([H])OC1=C([H])C(=C(N=C1[H])C1=C([H])SC([H])=C1[H])C1=C([H])C2=C(N([H])N=C2C([H])([H])[H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N([H])[C@]([H])(C([H])([H])OC1=C([H])C(=C(N=C1[H])C1=C([H])C([H])=C([H])S1)C1=C([H])C2=C(N([H])N=C2C([H])([H])[H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N([H])[C@]([H])(C([H])([H])OC1=C([H])C(=C(N=C1[H])C1=C([H])OC([H])=C1[H])C1=C([H])C2=C(N([H])N=C2C([H])([H])[H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N([H])C1=NC(C2=C(OC([H])=C2[H])C([H])([H])[H])=C(C([H])=C1OC([H])([H])[C@@]([H])(N([H])[H])C([H])([H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H])C1=C([H])C2=C(N=C1[H])N([H])N=C2C([H])([H])[H]
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[H]N([H])C1=NC(C2=C(OC([H])=C2[H])C([H])([H])[H])=C(C([H])=C1OC([H])([H])[C@@]([H])(N([H])[H])C([H])([H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H])C1=C([H])C2=C(N([H])N=C2C([H])([H])[H])C([H])=N1
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[H]N([H])C1(C2=C([H])C([H])=C(C([H])=C2[H])C2=NC3=C(C([H])=C2C2=C([H])C([H])=C([H])C([H])=C2[H])C2=NN([H])C(=O)N2C([H])=C3[H])C([H])([H])C([H])([H])C1([H])[H]
[H]OP(=O)(O[H])OC1=C(OP(=O)(O[H])O[H])C(OP(=O)(O[H])O[H])=C(OP(=O)(O[H])O[H])C([H])=C1[H]
[H]N(C1=NC([H])=C([H])C([H])=N1)S(=O)(=O)C1=C([H])C([H])=C(\N=N\[C@]2([H])C(=O)N(N=C2C([H])([H])[H])C(=O)C2=C([H])C([H])=C(Cl)C([H])=C2[H])C([H])=C1[H]
[H]N(C1=NC([H])=C([H])C([H])=N1)S(=O)(=O)C1=C([H])C([H])=C(\N=N\[C@]2([H])C(=O)N(N=C2C([H])([H])[H])C(=O)C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])=C1[H]
[H]N(C1=NC([H])=C([H])C([H])=N1)S(=O)(=O)C1=C([H])C([H])=C(\N=N\[C@@]2([H])C(=O)N(N=C2C([H])([H])[H])C(=O)C2=C([H])C([H])=C(C([H])=C2[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])=C1[H]
[H]N([H])C1=C([H])C([H])=C(C([H])=C1[H])C(=O)N1N=C(C([H])([H])[H])[C@@]([H])(\N=N\C2=C([H])C([H])=C(C([H])=C2[H])S(=O)(=O)N([H])C2=NC([H])=C([H])C([H])=N2)C1=O
[H]OC1=C([H])C([H])=C(C([H])=C1[H])C(=O)N1N=C(C([H])([H])[H])[C@]([H])(\N=N\C2=C([H])C([H])=C(C([H])=C2[H])S(=O)(=O)N([H])C2=NC([H])=C([H])C([H])=N2)C1=O
[H]C1=NC(=NC([H])=C1[H])N(C([H])([H])[H])S(=O)(=O)C1=C([H])C([H])=C(\N=N\[C@]2([H])C(=O)N(N=C2C([H])([H])[H])C(=O)C2=C([H])C([H])=C(Cl)C([H])=C2[H])C([H])=C1[H]
[H]OC1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NN([H])C2=C1C([H])([H])C1=C([H])C(=C([H])C([H])=C21)C(=O)N([H])[C@@]1([H])C([H])([H])C([H])([H])[C@]([H])(O[H])C([H])([H])C1([H])[H]
[H]N([H])C1=NC(C2=C(OC([H])=C2[H])C([H])([H])[H])=C(C([H])=C1OC([H])([H])[C@@]([H])(N([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C1=NC2=C(N=C1[H])N([H])N=C2C([H])([H])[H]
[H]N([H])[C@]([H])(C([H])([H])OC1=C([H])C(C2=NC3=C(N=C2[H])N([H])N=C3C([H])([H])[H])=C(N=C1N([H])C([H])([H])C([H])([H])[H])C1=C([H])OC([H])=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N([H])C1=NC(C2=C(OC([H])=C2[H])C([H])([H])[H])=C(C([H])=C1OC([H])([H])[C@@]([H])(N([H])[H])C([H])([H])C1=C(Cl)N([H])C2=C1C([H])=C([H])C([H])=C2[H])C1=NC2=C(N=C1[H])N([H])N=C2C([H])([H])[H]
[H]N1C(=O)N(C2=C1C([H])=C([H])C([H])=C2[H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C(C([H])=C2[H])C2=NC([H])=C(C([H])=C2C2=C([H])C([H])=C([H])C([H])=C2[H])C2=NN=NN2C([H])([H])[H])C([H])([H])C1([H])[H]
[H]O[C@@]1([H])[C@@]([H])(OP(=O)(O[H])O[H])[C@]([H])(O[H])[C@@]([H])([C@@]([H])(OP(=O)(O[H])O[H])[C@]1([H])OP(=O)(O[H])O[H])P(=O)(O[H])O[H]
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[H]N([H])C(=O)C1=C(C2=C(N1[H])C([H])=C([H])C([H])=C2[H])C([H])([H])[C@]([H])(N([H])[H])C([H])([H])OC1=C([H])C(C2=NC3=C(N=C2[H])N([H])N=C3C([H])([H])[H])=C(N=C1N([H])[H])C1=C(OC([H])=C1[H])C([H])([H])[H]
[H]N([H])[C@@]1(C([H])([H])N([H])C(=O)C2=C([H])C([H])=C(F)C([H])=C2F)C([H])([H])N(C2=C3C(=NC([H])=N2)N([H])C([H])=C3C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N([H])[C@@]1(C([H])([H])N([H])C(=O)C2=C([H])C([H])=C(F)C([H])=C2F)C([H])([H])N(C2=C3C(=NC([H])=N2)N([H])C([H])=C3C#N)C([H])([H])C1([H])[H]
[H]N([H])[C@@]1(C([H])([H])N([H])C(=O)C2=C([H])C([H])=C(Cl)C([H])=C2[H])C([H])([H])N(C2=C3C(=NC([H])=N2)N([H])C([H])=C3C([H])([H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N([H])[C@@]1(C([H])([H])N([H])C(=O)C2=C([H])C([H])=C(Cl)C([H])=C2[H])C([H])([H])N(C2=C3C(Cl)=C([H])N([H])C3=NC([H])=N2)C([H])([H])C1([H])[H]
[H]N([H])[C@@]1(C([H])([H])N([H])C(=O)C2=C([H])C([H])=C(Cl)C([H])=C2[H])C([H])([H])N(C2=C3C(=NC([H])=N2)N([H])C([H])=C3C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N([H])[C@@]1(C([H])([H])N([H])C(=O)C2=C([H])C([H])=C(Cl)C([H])=C2[H])C([H])([H])N(C2=C3C(=NC([H])=N2)N([H])C([H])=C3C#N)C([H])([H])C1([H])[H]
[H]N([H])[C@@]1(C([H])([H])N([H])C(=O)C2=C([H])C([H])=C(F)C([H])=C2[H])C([H])([H])N(C2=C3C(=NC([H])=N2)N([H])C([H])=C3C([H])([H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N([H])[C@@]1(C([H])([H])N([H])C(=O)C2=C([H])C([H])=C(F)C([H])=C2[H])C([H])([H])N(C2=C3C(Cl)=C([H])N([H])C3=NC([H])=N2)C([H])([H])C1([H])[H]
[H]N([H])[C@@]1(C([H])([H])N([H])C(=O)C2=C([H])C([H])=C(F)C([H])=C2[H])C([H])([H])N(C2=C3C(=NC([H])=N2)N([H])C([H])=C3C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N(C([H])([H])C([H])([H])[H])[C@@]1([H])C([H])([H])N(C2=C3C(=NC([H])=N2)N([H])C([H])=C3C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N(C(=O)N([H])[C@@]1([H])C([H])([H])N(C2=C3C(=NC([H])=N2)N([H])C([H])=C3C([H])([H])[H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N([C@@]1([H])C([H])([H])N(C2=C3C(=NC([H])=N2)N([H])C([H])=C3C([H])([H])[H])C([H])([H])C1([H])[H])S(=O)(=O)C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N([C@@]1([H])C([H])([H])N(C2=C3C(=NC([H])=N2)N([H])C([H])=C3C([H])([H])[H])C([H])([H])C1([H])[H])S(=O)(=O)C([H])([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C([H])C([H])=C1[H])[C@@]1([H])C([H])([H])N(C2=C3C(=NC([H])=N2)N([H])C([H])=C3C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N1C([H])=C(Cl)C2=C(N=C([H])N=C12)N1C([H])([H])C([H])([H])C2(C1([H])[H])C([H])([H])C([H])([H])N([H])C([H])([H])C2([H])[H]
[H]N([H])[C@@]1([H])C([H])([H])N(C2=C3C(Cl)=C([H])N([H])C3=NC([H])=N2)C([H])([H])C([H])([H])C1([H])[H]
[H]N([H])[C@@]1([H])C([H])([H])N(C2=C3C(=NC([H])=N2)N([H])C([H])=C3C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N([H])[C@@]1([H])C([H])([H])N(C2=C3C(Cl)=C([H])N([H])C3=NC([H])=N2)C([H])([H])C1([H])[H]
[H]N1C([H])=C(C#N)C2=C1N=C([H])N=C2N1C2=C([H])C([H])=C([H])C([H])=C2C2(C1([H])[H])C([H])([H])C([H])([H])N([H])C([H])([H])C2([H])[H]
[H]N(C1=NC([H])=NC2=C1C([H])=C([H])N2[H])C1=C([H])C([H])=C([H])C([H])=C1C1=NN=C([H])N1[H]
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[H]N([H])[C@@]1(C([H])([H])N([H])C(=O)C2=C([H])C([H])=C(F)C([H])=C2F)C([H])([H])N(C2=C3C(Cl)=C([H])N([H])C3=NC([H])=N2)C([H])([H])C1([H])[H]
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[H]N([H])C1=NC(=C([H])C2=C1C([H])=NC1=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C([H])=C21)C1=C([H])C(OC([H])([H])[C@@]([H])(N([H])[H])C([H])([H])C2=C([H])N([H])C3=C2C([H])=C([H])C([H])=C3[H])=C([H])N=C1[H]
[H]N([H])C1=NC(=C([H])C2=C1C([H])=NC1=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C([H])=C21)C1=C([H])C(OC([H])([H])[C@@]([H])(N([H])[H])C([H])([H])C2=C(Cl)C([H])=C([H])C([H])=C2[H])=C([H])N=C1[H]
[H]N([H])C1=NC(=C([H])C2=C1C([H])=NC1=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C([H])=C21)C1=C([H])C(OC([H])([H])[C@@]([H])(N([H])[H])C([H])([H])C2=C([H])C(Cl)=C([H])C([H])=C2[H])=C([H])N=C1[H]
[H]N([H])C1=NC(=C([H])C2=C1C([H])=NC1=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C([H])=C21)C1=C([H])C(OC([H])([H])[C@@]([H])(N([H])[H])C([H])([H])C2=C([H])C(Cl)=C(Cl)C([H])=C2[H])=C([H])N=C1[H]
[H]N([H])C1=NC(=C([H])C2=C1C([H])=NC1=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C([H])=C21)C1=C([H])C(OC([H])([H])[C@@]([H])(N([H])[H])C([H])([H])C2=C([H])C([H])=NC([H])=C2[H])=C([H])N=C1[H]
[H]OC(C#CC1=NC(O[C@@]([H])(C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])N([H])[H])=C([H])C2=C1N=C(N2C([H])([H])C([H])([H])[H])C1=NON=C1N([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]OC(C#CC1=NC(O[C@@]([H])(C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])N([H])[H])=C([H])C2=C1N=C(N2C([H])([H])C([H])([H])[H])C1=NON=C1N([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]OC(C#CC1=NC(OC([H])([H])[C@]([H])(N([H])[H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])=C([H])C2=C1N=C(N2C([H])([H])C([H])([H])[H])C1=NON=C1N([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]N([H])C1=NC(=C([H])C2=C1C([H])=NC1=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C([H])=C21)C1=C([H])C(OC([H])([H])C([H])([H])N([H])[H])=C([H])N=C1[H]
[H]N([H])C1=NC(=C([H])C2=C1C([H])=NC1=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C([H])=C21)C1=C([H])C(OC([H])([H])[C@@]([H])(N([H])[H])C([H])([H])[H])=C([H])N=C1[H]
[H]OC(C#CC1=NC(OC([H])([H])C([H])([H])C([H])([H])N([H])[H])=C([H])C2=C1N=C(N2C([H])([H])C([H])([H])[H])C1=NON=C1N([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]OC(C#CC1=NC(OC([H])([H])C([H])([H])N([H])[H])=C([H])C2=C1N=C(N2C([H])([H])C([H])([H])[H])C1=NON=C1N([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]OC(C#CC1=NC(=C([H])C2=C1N=C(N2C([H])([H])C([H])([H])[H])C1=NON=C1N([H])[H])C([H])([H])C([H])([H])C([H])([H])N([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]OC(C#CC1=NC(=C([H])C2=C1N=C(N2C([H])([H])C([H])([H])[H])C1=NON=C1N([H])[H])C([H])([H])N([H])C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]OC(C#CC1=NC(=C([H])C2=C1N=C(N2C([H])([H])C([H])([H])[H])C1=NON=C1N([H])[H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]OC(C#CC1=NC(=C([H])C2=C1N=C(N2C([H])([H])C([H])([H])[H])C1=NON=C1N([H])[H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])C1([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]OC(C#CC1=NC(OC([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])[H])=C([H])C2=C1N=C(N2C([H])([H])C([H])([H])[H])C1=NON=C1N([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]OC(C#CC1=NC(OC([H])([H])C([H])([H])N([H])C([H])([H])[H])=C([H])C2=C1N=C(N2C([H])([H])C([H])([H])[H])C1=NON=C1N([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]OC(C#CC1=NC(OC([H])([H])[C@]([H])(N([H])[H])C([H])([H])[H])=C([H])C2=C1N=C(N2C([H])([H])C([H])([H])[H])C1=NON=C1N([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]OC(C#CC1=NC(OC([H])([H])[C@]([H])(N([H])[H])C2=C([H])C([H])=C([H])C([H])=C2[H])=C([H])C2=C1N=C(N2C([H])([H])C([H])([H])[H])C1=NON=C1N([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]OC(C#CC1=NC(=C([H])C2=C1N=C(N2C([H])([H])C([H])([H])[H])C1=NON=C1N([H])[H])C([H])([H])N([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]OC(C#CC1=NC(=C([H])C2=C1N=C(N2C([H])([H])C([H])([H])[H])C1=NON=C1N([H])[H])C([H])([H])C([H])([H])N([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]N([H])[C@@]1(C([H])([H])N([H])C(=O)C2=C([H])C([H])=C(F)C([H])=C2[H])C([H])([H])N(C2=C3C(=NC([H])=N2)N([H])C([H])=C3C#N)C([H])([H])C1([H])[H]
[H]N([H])[C@@]1(C([H])([H])N([H])C(=O)C2=C([H])C([H])=C([H])C(F)=C2[H])C([H])([H])N(C2=C3C(=NC([H])=N2)N([H])C([H])=C3C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N([H])[C@@]1(C([H])([H])N([H])C(=O)C([H])([H])[H])C([H])([H])N(C2=C3C(=NC([H])=N2)N([H])C([H])=C3C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N([H])[C@@]1(C([H])([H])N([H])C(=O)C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])N(C2=C3C(=NC([H])=N2)N([H])C([H])=C3C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N([H])[C@@]1(C([H])([H])N([H])C(=O)C2=C([H])C([H])=C([H])C([H])=C2F)C([H])([H])N(C2=C3C(=NC([H])=N2)N([H])C([H])=C3C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N([H])[C@@]1(C([H])([H])N([H])C([H])=O)C([H])([H])N(C2=C3C(=NC([H])=N2)N([H])C([H])=C3C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N([H])[C@@]1(C([H])([H])N([H])C(Cl)=O)C([H])([H])N(C2=C3C(=NC([H])=N2)N([H])C([H])=C3C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N([H])[C@@]1(C([H])([H])N([H])C(=O)C(F)(F)F)C([H])([H])N(C2=C3C(=NC([H])=N2)N([H])C([H])=C3C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N([H])[C@@]1(C([H])([H])N([H])C(=O)OC2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])N(C2=C3C(=NC([H])=N2)N([H])C([H])=C3C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N(C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])[C@@]1([H])C([H])([H])N(C2=C3C(=NC([H])=N2)N([H])C([H])=C3C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N([H])[C@]([H])(C([H])([H])N([H])C1=NC([H])=C(S1)C1=C([H])C([H])=C2C([H])=NC([H])=NC2=C1[H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C(F)(F)F
[H]N([H])[C@]([H])(C([H])([H])N([H])C1=NC([H])=C(S1)C1=C([H])C([H])=C2N=NC([H])=C([H])C2=C1[H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C(F)(F)F
[H]N([H])[C@]([H])(C([H])([H])N([H])C1=NC([H])=C(S1)C1=C([H])C2=C(C([H])=C1[H])C(=O)N([H])C2([H])[H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C(F)(F)F
[H]N([H])[C@]([H])(C([H])([H])N([H])C1=NN=C(O1)C1=C([H])C([H])=C2C([H])=NC([H])=C([H])C2=C1[H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C(F)(F)F
[H]N([H])C1=C([H])C2=C([H])C(=C([H])C([H])=C2C([H])=N1)C1=C([H])N=C(S1)N([H])C([H])([H])[C@@]([H])(N([H])[H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C(F)(F)F
[H]N([H])[C@]([H])(C([H])([H])N([H])C1=NN=C(S1)C1=C([H])C2=C(N([H])N=C2C([H])([H])[H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C(Cl)=C1[H]
[H]N([H])[C@]([H])(C([H])([H])N([H])C1=NN=C(S1)C1=C([H])C2=C(N([H])N=C2C([H])([H])[H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C(=C1[H])C(F)(F)F
[H]N([H])[C@]([H])(C([H])([H])N([H])C1=NN=C(S1)C1=C([H])C2=C([H])C([H])=NC([H])=C2C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C(F)(F)F
[H]N([H])[C@]([H])(C([H])([H])N([H])C1=NC([H])=C(S1)C1=C([H])C([H])=C2C([H])=NC([H])=C([H])C2=C1[H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C(F)(F)F
[H]N([H])[C@]([H])(C([H])([H])N([H])C1=C([H])N=C(S1)C1=C([H])C([H])=C2C([H])=NC([H])=C([H])C2=C1[H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C(F)(F)F
[H]N([H])[C@]([H])(C([H])([H])N([H])C1=C([H])C(=NO1)C1=C([H])C([H])=C2C([H])=NC([H])=C([H])C2=C1[H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C(F)(F)F
[H]N([H])[C@@]([H])(C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C(F)(F)F)C([H])([H])C([H])([H])C1=C([H])C(=NO1)C1=C([H])C([H])=C2C([H])=NC([H])=C([H])C2=C1[H]
[H]N([H])[C@@]([H])(C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C(F)(F)F)C([H])([H])C([H])([H])C1=NC(=NO1)C1=C([H])C([H])=C2C([H])=NC([H])=C([H])C2=C1[H]
[H]N([H])[C@]([H])(C([H])([H])N([H])C1=NC([H])=C(S1)C1=C([H])C([H])=C2C([H])=NN([H])C2=C1[H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C(F)(F)F
[H]N([H])[C@]([H])(C([H])([H])N([H])C1=NC([H])=C(S1)C1=C([H])C([H])=C2N([H])C(=O)N(C2=C1[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C(F)(F)F
[H]N([H])[C@]([H])(C([H])([H])N([H])C1=NC([H])=C(S1)C1=C([H])C([H])=C2N([H])C(=O)C([H])([H])C([H])([H])C2=C1[H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C(F)(F)F
[H]N([H])[C@]([H])(C([H])([H])N([H])C1=NC([H])=C(S1)C1=C([H])C2=C(C([H])=NN([H])C2=O)C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C(F)(F)F
[H]N([H])C(=O)C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])N=C(S1)N([H])C([H])([H])[C@@]([H])(N([H])[H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C(F)(F)F
[H]N([H])[C@]([H])(C([H])([H])N([H])C1=NN=C(S1)C1=C([H])C2=C(N([H])N=C2C2([H])C([H])([H])C2([H])[H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C(F)(F)F
[H]N([H])[C@]([H])(C([H])([H])N([H])C1=NN=C(S1)C1=C([H])C2=C(N([H])N=C2C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C(=C1[H])C(F)(F)F
[H]N([H])[C@]([H])(C([H])([H])N([H])C1=NN=C(S1)C1=C([H])C2=C(N([H])N=C2[H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C(=C1[H])C(F)(F)F
[H]N([H])[C@]([H])(C([H])([H])N([H])C1=NN=C(S1)C1=C([H])C2=C(N([H])N=C2[H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]N([H])[C@]([H])(C([H])([H])N([H])C1=NN=C(S1)C1=C([H])C2=C(N([H])N=C2[H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]N([H])[C@]([H])(C([H])([H])N([H])C1=NN=C(S1)C1=C([H])C2=C(N([H])N=C2C([H])([H])[H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C(F)(F)F
[H]N([H])[C@]([H])(C([H])([H])N([H])C1=NN=C(S1)C1=C([H])C2=C(N([H])N=C2C([H])([H])[H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C(Cl)C([H])=C1Cl
[H]N([H])[C@]([H])(C([H])([H])N([H])C1=NN=C(S1)C1=C([H])C2=C(N([H])N=C2C([H])([H])[H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C(F)C(F)=C1[H]
[H]N([H])[C@]([H])(C([H])([H])N([H])C1=NN=C(S1)C1=C([H])C2=C(N([H])N=C2C([H])([H])C([H])([H])[H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N([H])[C@]([H])(C([H])([H])N([H])C1=NN=C(S1)C1=C([H])C2=C(N([H])N=C2C([H])([H])[H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N([H])[C@]([H])(C([H])([H])N([H])C1=NN=C(S1)C1=C([H])C2=C(N([H])N=C2C([H])([H])[H])C([H])=C1[H])C([H])([H])C1=C(F)C([H])=C([H])C([H])=C1[H]
[H]N([H])[C@]([H])(C([H])([H])N([H])C1=NN=C(S1)C1=C([H])C2=C(N([H])N=C2C([H])([H])[H])C([H])=C1[H])C([H])([H])C1=C(Cl)C([H])=C([H])C([H])=C1[H]
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[H]N([H])[C@]([H])(C([H])([H])N([H])C1=NN=C(S1)C1=C([H])C2=C(N([H])N=C2C([H])([H])[H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C(F)=C1[H]
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[H]N([H])[C@]([H])(C([H])([H])N([H])C1=NN=C(S1)C1=C([H])C2=C([H])C(=NC([H])=C2C([H])=C1[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C(F)(F)F
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CC1=CC2=C(N=CN=C2C=C1)N1CCN(CC1)C(=O)[C@H](N)CC1=CC=C(Cl)C=C1
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CC(=O)NC1=CC2=C(N=CN=C2C=C1)N1CCN(CC1)C(=O)[C@H](N)CC1=CC=C(Cl)C=C1
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CC(C)(C)C1=CC2=C(N=CN=C2C=C1)N1CCN(CC1)C(=O)[C@H](N)CC1=CC=C(Cl)C=C1
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CC1=CNC2=C1C(=NC=N2)N1CCN(CC1)C(=O)[C@H](N)CC1=CC=C(Cl)C=C1
CCC1=CNC2=C1C(=NC=N2)N1CCN(CC1)C(=O)[C@H](N)CC1=CC=C(Cl)C=C1
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CC1=CNC2=C1C(=NC=N2)N1CCN(CC1)C(=O)[C@H](CN)CC1=CC=C(Cl)C=C1
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CC1=CNC2=C1C(=NC=N2)N1CCN(CC1)C(=O)[C@H](N)CC1=CC=C(F)C=C1
CC1=CNC2=C1C(=NC=N2)N1CCN(CC1)C(=O)[C@H](N)C1CC2=CC=CC=C2C1
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CC1=CC=C(C=N1)C1=NC2=C(C)N=C(N)N=C2N([C@H]2CC[C@@H](CC2)OCCO)C1=O
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CC1=CC=C(C=N1)C1=NC2=C(C)N=C(N)N=C2N([C@H]2CC[C@H](O)CC2)C1=O
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[H]N(C([H])([H])[C@@]([H])(C(=O)N1C([H])([H])C([H])([H])N(C2=NC([H])=NC3=C2[C@@]([H])(SC3([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C([H])([H])[C@@]([H])(C(=O)N1C([H])([H])C([H])([H])N(C2=NC([H])=NC3=C2[C@@]([H])(SC3([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C(Cl)C(F)=C1[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C([H])([H])[C@@]([H])(C(=O)N1C([H])([H])C([H])([H])N(C2=NC([H])=NC3=C2[C@@]([H])(SC3([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C(F)C(F)=C1[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N([H])C1(C([H])([H])[C@@]([H])(C(=O)N2C([H])([H])C([H])([H])N(C3=NC([H])=NC4=C3[C@@]([H])(SC4([H])[H])C([H])([H])[H])C([H])([H])C2([H])[H])C([H])([H])C2=C([H])C([H])=C(Cl)C(F)=C2[H])C([H])([H])C1([H])[H]
[H]N([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[C@@]([H])(C(=O)N1C([H])([H])C([H])([H])N(C2=NC([H])=NC3=C2[C@@]([H])(SC3([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]N([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[C@@]([H])(C(=O)N1C([H])([H])C([H])([H])N(C2=NC([H])=NC3=C2[C@@]([H])(SC3([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C(Cl)C(F)=C1[H]
[H]N(C([H])([H])[C@@]([H])(C(=O)N1C([H])([H])C([H])([H])N(C2=NC([H])=NC3=C2[C@@]([H])(OC3([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C([H])([H])[C@@]([H])(C(=O)N1C([H])([H])C([H])([H])N(C2=NC([H])=NC3=C2[C@@]([H])(OC3([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C(Cl)C(F)=C1[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C([H])([H])[C@@]([H])(C(=O)N1C([H])([H])C([H])([H])N(C2=NC([H])=NC3=C2[C@@]([H])(OC3([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C(Cl)C([H])=C1[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[C@@]([H])(C(=O)N1C([H])([H])C([H])([H])N(C2=NC([H])=NC3=C2[C@@]([H])(OC3([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C(Cl)C(F)=C1[H]
[H]N([H])[C@@]([H])(C(=O)N1C([H])([H])C([H])([H])N(C2=NC([H])=NC3=C2C([H])([H])SC3([H])[H])C([H])([H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]N([H])[C@@]([H])(C(=O)N1C([H])([H])C([H])([H])N(C2=NC([H])=NC3=C2[C@]([H])(SC3([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]N([H])[C@@]([H])(C(=O)N1C([H])([H])C([H])([H])N(C2=NC([H])=NC3=C2[C@]([H])(SC3([H])[H])C([H])([H])C([H])([H])[H])C([H])([H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]N([H])[C@@]([H])(C(=O)N1C([H])([H])C([H])([H])N(C2=NC([H])=NC3=C2[C@@]([H])(SC3([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C(Cl)C(F)=C1[H]
[H]N([H])[C@@]([H])(C(=O)N1C([H])([H])C([H])([H])N(C2=NC([H])=NC3=C2[C@@]([H])(SC3([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]N([H])[C@@]([H])(C(=O)N1C([H])([H])C([H])([H])N(C2=NC([H])=NC3=C2[C@@]([H])(SC3([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C(F)C(F)=C1[H]
[H]N([H])[C@@]([H])(C(=O)N1C([H])([H])C([H])([H])N(C2=C3C(=NC([H])=N2)C([H])([H])S[C@@]3([H])C([H])([H])[H])C([H])([H])C1([H])[H])C([H])([H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H]
[H]N([H])[C@@]([H])(C(=O)N1C([H])([H])C([H])([H])N(C2=NC([H])=NC3=C2[C@@]([H])(OC3([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]N([H])C1(C([H])([H])C1([H])[H])[C@@]([H])(C(=O)N1C([H])([H])C([H])([H])N(C2=NC([H])=NC3=C2[C@@]([H])(SC3([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]N(C(=O)C1=C([H])C([H])=C(C([H])=C1[H])N1C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C1=C([H])C(=C([H])N([H])C1=O)C1=NC(N([H])C([H])([H])[H])=C([H])N=C1[H]
[H]N(C(=O)C([H])([H])[H])C1=NC2=C([H])C([H])=C(C([H])=C2S1)C1=C([H])C([H])=NC(=N1)N(C([H])([H])C([H])([H])[H])S(=O)(=O)C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]N(C(=O)C([H])([H])[H])C1=NC2=C([H])C([H])=C(C([H])=C2S1)C1=C([H])C([H])=NC(=N1)N([H])S(=O)(=O)C1=C([H])C([H])=C([H])C([H])=C1F
[H]N(C(=O)C([H])([H])[H])C1=NC2=C([H])C([H])=C(C([H])=C2S1)C1=C([H])C([H])=NC(=N1)N(C([H])([H])[H])S(=O)(=O)C1=C([H])C([H])=C([H])C([H])=C1F
[H]N(C(=O)C([H])([H])[H])C1=NC2=C([H])C([H])=C(C([H])=C2S1)C1=C([H])C([H])=NC(=N1)N([H])S(=O)(=O)C1=C([H])C([H])=C([H])C(F)=C1[H]
[H]N(C(=O)C([H])([H])[H])C1=NC2=C([H])C([H])=C(C([H])=C2S1)C1=C([H])C([H])=NC(=N1)N([H])S(=O)(=O)C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]N(C(=O)C([H])([H])[H])C1=NC2=C([H])C([H])=C(C([H])=C2S1)C1=C([H])C([H])=NC(=N1)N([H])S(=O)(=O)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H]
[H]N(C(=O)C([H])([H])[H])C1=NC2=C([H])C([H])=C(C([H])=C2S1)C1=C([H])C([H])=NC(=N1)N(C([H])([H])[H])S(=O)(=O)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H]
[H]N(C(=O)C([H])([H])[H])C1=NC2=C([H])C([H])=C(C([H])=C2S1)C1=C([H])C([H])=NC(N([H])S(=O)(=O)C2=C([H])C([H])=C(OC([H])([H])[H])C([H])=C2[H])=C1[H]
[H]N(C(=O)C([H])([H])[H])C1=NC2=C([H])C([H])=C(C([H])=C2S1)C1=C([H])N=C([H])C(N([H])S(=O)(=O)C2=C([H])C([H])=C(OC([H])([H])[H])C([H])=C2[H])=C1[H]
[H]N(C(=O)C([H])([H])[H])C1=NC2=C([H])C([H])=C(C([H])=C2S1)C1=C([H])N=C([H])C(=N1)N([H])S(=O)(=O)C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]N(C(=O)C([H])([H])[H])C1=NC2=C([H])C([H])=C(C([H])=C2S1)C1=C([H])C([H])=C([H])C(N([H])S(=O)(=O)C2=C([H])C([H])=C(OC([H])([H])[H])C([H])=C2[H])=C1[H]
[H]N(C(=O)C([H])([H])[H])C1=NC2=C([H])C([H])=C(C([H])=C2S1)C1=C([H])N=C(C#N)C(N([H])S(=O)(=O)C2=C([H])C([H])=C(OC([H])([H])[H])C([H])=C2[H])=C1[H]
[H]N(C(=O)C([H])([H])[H])C1=NC2=C([H])C([H])=C(C([H])=C2S1)C1=C([H])N=C(C(N([H])S(=O)(=O)C2=C([H])C([H])=C(OC([H])([H])[H])C([H])=C2[H])=C1[H])C([H])([H])[H]
[H]N(C(=O)C([H])([H])[H])C1=NC2=C([H])C([H])=C(C([H])=C2S1)C1=C([H])N=C(Cl)C(N([H])S(=O)(=O)C2=C([H])C([H])=C(OC([H])([H])[H])C([H])=C2[H])=C1[H]
[H]N(C(=O)C([H])([H])[H])C1=NC2=C([H])C([H])=C(C([H])=C2S1)C1=C([H])N=C(Cl)C(N([H])S(=O)(=O)C2=C([H])C([H])=C([H])C([H])=C2[H])=C1[H]
[H]N(C(=O)C([H])([H])[H])C1=NC2=C([H])C([H])=C(C([H])=C2S1)C1=C([H])N=C(Cl)C(N([H])S(=O)(=O)C2=C([H])C([H])=C([H])C([H])=C2C(F)(F)F)=C1[H]
[H]N(C(=O)C([H])([H])[H])C1=NC2=C([H])C([H])=C(C([H])=C2S1)C1=C([H])N=C(Cl)C(N([H])S(=O)(=O)C2=C([H])C([H])=C([H])C(=C2[H])C(F)(F)F)=C1[H]
[H]N(C(=O)C([H])([H])[H])C1=NC2=C([H])C([H])=C(C([H])=C2S1)C1=C([H])N=C(Cl)C(N([H])S(=O)(=O)C2=C([H])C([H])=C(C([H])=C2[H])C(F)(F)F)=C1[H]
[H]N(C(=O)C([H])([H])[H])C1=NC2=C([H])C([H])=C(C([H])=C2S1)C1=C([H])N=C(Cl)C(N([H])S(=O)(=O)C2=C([H])C([H])=C([H])C([H])=C2Cl)=C1[H]
[H]N(C(=O)C([H])([H])[H])C1=NC2=C([H])C([H])=C(C([H])=C2S1)C1=C([H])N=C(Cl)C(N([H])S(=O)(=O)C2=C([H])C([H])=C([H])C(Cl)=C2[H])=C1[H]
[H]N(C(=O)C([H])([H])[H])C1=NC2=C([H])C([H])=C(C([H])=C2S1)C1=C([H])N=C(Cl)C(N([H])S(=O)(=O)C2=C([H])C([H])=C(Cl)C([H])=C2[H])=C1[H]
[H]N(C(=O)C([H])([H])[H])C1=NC2=C([H])C([H])=C(C([H])=C2S1)C1=C([H])N=C(Cl)C(N([H])S(=O)(=O)C2=C([H])C([H])=C([H])C(=C2[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])=C1[H]
[H]N(C(=O)C([H])([H])[H])C1=NC2=C([H])C([H])=C(C([H])=C2S1)C1=C([H])N=C(Cl)C(N([H])S(=O)(=O)C2=C([H])C([H])=C(C([H])=C2[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])=C1[H]
[H]N(C(=O)C([H])([H])[H])C1=NC2=C([H])C([H])=C(C([H])=C2S1)C1=C([H])N=C(Cl)C(N([H])S(=O)(=O)C2=C([H])C([H])=C([H])C([H])=C2F)=C1[H]
[H]N(C(=O)C([H])([H])[H])C1=NC2=C([H])C([H])=C(C([H])=C2S1)C1=C([H])N=C(Cl)C(N([H])S(=O)(=O)C2=C([H])C([H])=C([H])C(F)=C2[H])=C1[H]
[H]N(C(=O)C([H])([H])[H])C1=NC2=C(S1)C([H])=C(C([H])=C2[H])C1=C([H])N=C(Cl)C(N([H])S(=O)(=O)C2=C([H])C([H])=C(F)C([H])=C2[H])=C1[H]
[H]O[C@]([H])(C([H])([H])N(C([H])([H])C([H])([H])OC([H])([H])C([H])([H])[H])S(=O)(=O)C1=C(C([H])=C([H])C([H])=C1C([H])([H])[H])C([H])([H])[H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])[C@]2(OC3=C([H])C([H])=C4N([H])N=C([H])C4=C3C([H])([H])C2([H])[H])C1([H])[H]
[H]O[C@]([H])(C([H])([H])N(C([H])([H])C([H])([H])OC([H])([H])C([H])([H])[H])S(=O)(=O)C1=C(C([H])=C([H])C([H])=C1C([H])([H])[H])C([H])([H])[H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])[C@]2(OC3=C([H])C4=C(C([H])=C3C([H])([H])C2([H])[H])C(=O)N([H])C4([H])[H])C1([H])[H]
[H]O[C@]([H])(C([H])([H])N(C([H])([H])C([H])([H])OC([H])([H])C([H])([H])[H])S(=O)(=O)C1=C(C([H])=C([H])C([H])=C1C([H])([H])[H])C([H])([H])[H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])[C@]2(OC3=C([H])C([H])=C(C([H])=C3C([H])([H])C2([H])[H])C(=O)N([H])[H])C1([H])[H]
[H]OC1=C([H])C([H])=C2O[C@@]3(C([H])([H])N(C([H])([H])[C@]([H])(O[H])C([H])([H])N(C([H])([H])C([H])([H])OC([H])([H])C([H])([H])[H])S(=O)(=O)C4=C(C([H])=C([H])C([H])=C4C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C3([H])[H])C([H])([H])C([H])([H])C2=C1[H]
[H]OC1=C([H])C([H])=C2O[C@@]3(C([H])([H])N(C([H])([H])[C@]([H])(O[H])C([H])([H])N(C([H])([H])C([H])([H])OC([H])([H])C([H])([H])[H])S(=O)(=O)C4=C(ON=C4C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C3([H])[H])C([H])([H])C([H])([H])C2=C1[H]
[H]O[C@]([H])(C([H])([H])N(C([H])([H])C([H])([H])OC([H])([H])C([H])([H])[H])S(=O)(=O)C1=C(C([H])=C([H])C([H])=C1C([H])([H])[H])C([H])([H])[H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])[C@]2(OC3=C([H])C([H])=C(C#N)C([H])=C3C([H])([H])C2([H])[H])C1([H])[H]
[H]O[C@]([H])(C([H])([H])N(C([H])([H])C([H])([H])OC([H])([H])C([H])([H])[H])S(=O)(=O)C1=C(C([H])=C([H])C([H])=C1C([H])([H])[H])C([H])([H])[H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])[C@]2(OC3=C([H])C([H])=C(F)C([H])=C3C([H])([H])C2([H])[H])C1([H])[H]
[H]OC1=C([H])C([H])=C2O[C@]3(C([H])([H])N(C([H])([H])[C@]([H])(O[H])C([H])([H])N(C([H])([H])C([H])([H])OC([H])(C([H])([H])[H])C([H])([H])[H])S(=O)(=O)C4=C(ON=C4C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C3([H])[H])C([H])([H])C(=O)C2=C1[H]
[H]OC1=C([H])C([H])=C2O[C@@]3(C([H])([H])N(C([H])([H])[C@]([H])(O[H])C([H])([H])N(C([H])([H])C([H])([H])OC([H])([H])C([H])([H])[H])S(=O)(=O)C4=C(C([H])=C([H])C([H])=C4C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C3([H])[H])C([H])([H])C(=O)C2=C1[H]
[H]OC1=C([H])C([H])=C2O[C@@]3(C([H])([H])N(C([H])([H])[C@]([H])(O[H])C([H])([H])N(C([H])([H])C4=C([H])C([H])=C([H])C([H])=C4[H])S(=O)(=O)C4=C(ON=C4C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C3([H])[H])C([H])([H])C(=O)C2=C1[H]
[H]N(C(=O)C([H])([H])[H])C1=NC2=C([H])C([H])=C(C([H])=C2S1)C1=C([H])C([H])=NC(=N1)N([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)C([H])([H])[H])C1=NC2=C([H])C([H])=C(C([H])=C2S1)C1=C([H])C([H])=NC(=N1)N([H])C(C1=C([H])C([H])=C([H])C([H])=C1[H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)C([H])([H])[H])C1=NC2=C([H])C([H])=C(C([H])=C2S1)C1=C([H])C([H])=NC(=N1)N([H])S(=O)(=O)C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]N(C(=O)C([H])([H])[H])C1=NC2=C([H])C([H])=C(C([H])=C2S1)C1=C([H])C([H])=NC(=N1)N(C([H])([H])[H])S(=O)(=O)C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]OC1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])[H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=N[H])N([H])[H])C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=N[H])N([H])[H])C([H])([H])C([H])([H])C([H])([H])[H])C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[H])C([H])([H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])N([H])[H]
[H]OC1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])[H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=N[H])N([H])[H])C([H])([H])N([H])[H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=N[H])N([H])[H])C([H])([H])C([H])([H])C([H])([H])[H])C(=O)N([H])[C@]([H])(C(=O)N([H])[C@]([H])(C(=O)N([H])[H])C([H])([H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])N([H])[H]
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[H]OC1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[C@]1([H])N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)C([H])([H])N(C(=O)[C@@]([H])(N([H])[H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=N[H])N([H])[H])C([H])([H])C([H])([H])N([H])C(=O)N([H])C([H])([H])C([H])([H])C([H])([H])N(C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C1=O)C([H])([H])N([H])[H])C([H])([H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C(=O)N([H])[H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=N[H])N([H])[H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]OC1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[C@]1([H])N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)C([H])([H])N(C(=O)[C@@]([H])(N([H])[H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=N[H])N([H])[H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=O)N([H])C([H])([H])C([H])([H])C([H])([H])N(C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C1=O)C([H])([H])N([H])[H])C([H])([H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C(=O)N([H])[H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=N[H])N([H])[H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]OC1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[C@]1([H])N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)C([H])([H])N(C(=O)[C@@]([H])(N([H])[H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=N[H])N([H])[H])C([H])([H])C([H])([H])N([H])C(=O)N([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N(C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C1=O)C([H])([H])N([H])[H])C([H])([H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C(=O)N([H])[H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=N[H])N([H])[H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]OC1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[C@]1([H])N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)C([H])([H])N(C(=O)[C@@]([H])(N([H])[H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=N[H])N([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=O)N([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N(C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C1=O)C([H])([H])N([H])[H])C([H])([H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C(=O)N([H])[H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=N[H])N([H])[H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]OC1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[C@]1([H])N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)C([H])([H])N([H])C([H])([H])C([H])([H])N([H])C(=O)N([H])C([H])([H])C([H])([H])N(C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C1=O)C([H])([H])N([H])[H])C([H])([H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C(=O)N([H])[H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=N[H])N([H])[H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]N([H])C1=NC2=C([H])C([H])=C(C([H])=C2S1)C1=C([H])N=C(Cl)C(N([H])S(=O)(=O)C2=C([H])C([H])=C(F)C([H])=C2[H])=C1[H]
[H]N(C1=C([H])C(=C([H])N=C1Cl)C1=C([H])C([H])=C2N=C([H])SC2=C1[H])S(=O)(=O)C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]N(C(=O)C([H])([H])[H])C1=C([H])N2N=C(C([H])=C([H])C2=N1)C1=C([H])N=C(Cl)C(N([H])S(=O)(=O)C2=C([H])C([H])=C(F)C([H])=C2[H])=C1[H]
[H]N([H])C1=C([H])N2N=C(C([H])=C([H])C2=N1)C1=C([H])N=C(Cl)C(N([H])S(=O)(=O)C2=C([H])C([H])=C(F)C([H])=C2[H])=C1[H]
[H]N(C1=C([H])C(=C([H])N=C1Cl)C1=NN2C([H])=C([H])N=C2C([H])=C1[H])S(=O)(=O)C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]N(C(=O)C([H])([H])[H])C1=C([H])N2C([H])=C(C([H])=C([H])C2=N1)C1=C([H])N=C(Cl)C(N([H])S(=O)(=O)C2=C([H])C([H])=C(F)C([H])=C2[H])=C1[H]
[H]N(C1=C([H])C(=C([H])N=C1Cl)C1=C([H])N2C([H])=C([H])N=C2C([H])=C1[H])S(=O)(=O)C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]N(C(=O)C([H])([H])[H])C1=NC2=C(N1[H])C([H])=C(C([H])=C2[H])C1=C([H])N=C(Cl)C(N([H])S(=O)(=O)C2=C([H])C([H])=C(F)C([H])=C2[H])=C1[H]
[H]N(C(=O)C([H])([H])[H])C1=NC2=C(O1)C([H])=C(C([H])=C2[H])C1=C([H])N=C(Cl)C(N([H])S(=O)(=O)C2=C([H])C([H])=C(F)C([H])=C2[H])=C1[H]
[H]N([H])C1=NC2=C(O1)C([H])=C(C([H])=C2[H])C1=C([H])N=C(Cl)C(N([H])S(=O)(=O)C2=C([H])C([H])=C(F)C([H])=C2[H])=C1[H]
[H]N(C(=O)C1=C([H])C2=C([H])C([H])=NC([H])=C2C([H])=C1[H])[C@]([H])(C1=C([H])C(Cl)=C(Cl)C([H])=C1[H])[C@@]1([H])C([H])([H])N([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(C(=O)C1=C([H])C2=C([H])C([H])=NC([H])=C2C([H])=C1[H])[C@@]([H])(C1=C([H])C(Cl)=C(Cl)C([H])=C1[H])[C@@]1([H])C([H])([H])N([H])C([H])([H])C1([H])[H]
[H]N(C(=O)C1=C([H])C2=C([H])C([H])=NC([H])=C2C([H])=C1[H])[C@@]([H])(C1=C([H])C(Cl)=C(Cl)C([H])=C1[H])C1([H])C([H])([H])N([H])C1([H])[H]
[H]N(C(=O)C1=C([H])C2=C([H])C([H])=NC([H])=C2C([H])=C1[H])[C@@]([H])(C1=C([H])C(Cl)=C(Cl)C([H])=C1[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(C(=O)C1=C([H])C2=C([H])C([H])=NC([H])=C2C([H])=C1[H])[C@@]([H])(C1=C([H])C(Cl)=C(Cl)C([H])=C1[H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H]
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[H]N(C(=O)C1=C([H])C2=C([H])C([H])=NC([H])=C2C([H])=C1[H])[C@@]([H])(C1=C([H])C(Cl)=C(Cl)C([H])=C1[H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C(C([H])=C2[H])C(F)(F)F)C([H])([H])C1([H])[H]
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[H]N([H])[C@]([H])(C([H])([H])N([H])C1=NN=C(S1)C1=C([H])C([H])=C2N([H])C(=O)C([H])([H])C2=C1[H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C(F)(F)F
[H]N(C(=O)C1=C([H])C2=C([H])C(F)=NC([H])=C2C([H])=C1[H])[C@]([H])(C1=C([H])C(Cl)=C(Cl)C([H])=C1[H])C1([H])C([H])([H])C([H])([H])N([H])C([H])([H])C1([H])[H]
[H]N([H])[C@]([H])(C([H])([H])N([H])C(=O)C1=C([H])C2=C([H])C([H])=NC([H])=C2C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C(F)(F)F
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[H]N(C(=O)C1=C([H])C2=C([H])C([H])=NC([H])=C2C([H])=C1[H])[C@]([H])(C1=C([H])C([H])=C(Cl)C([H])=C1[H])C1([H])C([H])([H])C([H])([H])N([H])C([H])([H])C1([H])[H]
[H]N(C(=O)C1=C([H])C2=C([H])C([H])=NC([H])=C2C([H])=C1[H])[C@]([H])(C1=C([H])C(F)=C(Cl)C([H])=C1[H])C1([H])C([H])([H])C([H])([H])N([H])C([H])([H])C1([H])[H]
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[H]N(C(=O)C1=C([H])C2=C([H])C([H])=NC([H])=C2C([H])=C1[H])[C@]([H])(C1=C([H])C(Cl)=C(Cl)N=C1[H])C1([H])C([H])([H])C([H])([H])N([H])C([H])([H])C1([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C2N([H])C(=O)C([H])([H])C2=C1[H])[C@]([H])(C1=C([H])C(Cl)=C(Cl)C([H])=C1[H])C1([H])C([H])([H])C([H])([H])N([H])C([H])([H])C1([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C2N([H])C(=O)OC2=C1[H])[C@]([H])(C1=C([H])C(Cl)=C(Cl)C([H])=C1[H])C1([H])C([H])([H])C([H])([H])N([H])C([H])([H])C1([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C2N([H])N=C([H])C2=C1[H])[C@]([H])(C1=C([H])C(Cl)=C(Cl)C([H])=C1[H])C1([H])C([H])([H])C([H])([H])N([H])C([H])([H])C1([H])[H]
[H]N(C(=O)C1=C([H])C2=C(C([H])=NN=C2[H])C([H])=C1[H])[C@]([H])(C1=C([H])C(Cl)=C(Cl)C([H])=C1[H])C1([H])C([H])([H])C([H])([H])N([H])C([H])([H])C1([H])[H]
[H]N(C(=O)C1=C([H])C2=C([H])C([H])=NC([H])=C2C([H])=C1OC([H])([H])[H])[C@]([H])(C1=C([H])C(Cl)=C(Cl)C([H])=C1[H])C1([H])C([H])([H])C([H])([H])N([H])C([H])([H])C1([H])[H]
[H]N(C(=O)C1=C([H])C2=C([H])C([H])=NC([H])=C2C([H])=C1C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])[C@]([H])(C1=C([H])C(Cl)=C(Cl)C([H])=C1[H])C1([H])C([H])([H])C([H])([H])N([H])C([H])([H])C1([H])[H]
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[H]OC1=C([H])C2=C3C(OC(=O)C4=C3C(OC2=O)=C(O[H])C(O[H])=C4[H])=C1O[H]
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[H]N([H])C1=C2C([H])=C(C(=NC2=NC([H])=N1)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1C([H])([H])C([H])([H])C([H])(C2=NN([H])C(=C2[H])C2=C([H])C([H])=NC([H])=C2[H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N([H])C1=C2C([H])=C(C3=C([H])C([H])=C([H])C([H])=C3[H])C(=NC2=NC([H])=N1)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1C([H])([H])C([H])([H])C([H])(N2C(=NC3=C2C([H])=C([H])C([H])=C3[H])C([H])([H])[H])C([H])([H])C1([H])[H]
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[H]N([H])C1=C2C([H])=C(C3=C([H])C([H])=C([H])C([H])=C3[H])C(=NC2=NC([H])=N1)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1C([H])([H])C([H])([H])C([H])(N2C(=O)N([H])C3=C2C([H])=C([H])C([H])=C3[H])C([H])([H])C1([H])[H]
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[H]N([H])C1=NN(C2=C1C([H])=C(C1=C([H])C([H])=C([H])C([H])=C1[H])C(=N2)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1C([H])([H])C([H])([H])C([H])(N2C(=O)N([H])C3=C2C([H])=C([H])C([H])=C3[H])C([H])([H])C1([H])[H])C([H])([H])[H]
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[H]N(C1=C(C#N)C([H])=C(C2=C([H])C([H])=C([H])C([H])=C2[H])C(=N1)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1C([H])([H])C([H])([H])C([H])(N2C(=O)N([H])C3=C2C([H])=C([H])C([H])=C3[H])C([H])([H])C1([H])[H])C([H])([H])[H]
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[H]N([H])C1(C2=C([H])C([H])=C(C([H])=C2[H])C2=NN3C([H])=C([H])C([H])=C3C([H])=C2C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C1([H])[H]
[H]N([H])C1(C2=C([H])C([H])=C(C([H])=C2[H])C2=NC3=C([H])C([H])=C([H])C([H])=C3C([H])=C2C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C1([H])[H]
[H]N([H])C1=NC([H])=C(N=C1C(=O)N([H])C([H])([H])[H])C1=C([H])C(=C(Cl)C([H])=C1[H])S(=O)(=O)N([H])C1=C([H])C([H])=C([H])C(F)=C1F
[H]N([H])C1=NC([H])=C(N=C1C(=O)N([H])C([H])([H])[H])C1=C([H])C(=C(Cl)C([H])=C1[H])S(=O)(=O)N([H])C1=C([H])C([H])=C([H])C(F)=C1C([H])([H])[H]
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[H]O[C@@]1([H])C2=C(C(=NC([H])=N2)N2C([H])([H])C([H])([H])N(C(=O)[C@@]([H])(C3=C([H])C(F)=C(C([H])=C3[H])C(F)(F)F)C([H])([H])N([H])C([H])([H])C3([H])C([H])([H])C3([H])[H])C([H])([H])C2([H])[H])[C@]([H])(C([H])([H])[H])C1([H])[H]
[H]OC([H])([H])C(N([H])C([H])([H])[C@@]([H])(C(=O)N1C([H])([H])C([H])([H])N(C2=NC([H])=NC3=C2[C@]([H])(C([H])([H])[H])C([H])([H])[C@@]3([H])O[H])C([H])([H])C1([H])[H])C1=C([H])C(F)=C(C([H])=C1[H])C(F)(F)F)(C([H])([H])[H])C([H])([H])[H]
[H]O[C@@]1([H])C2=C(C(=NC([H])=N2)N2C([H])([H])C([H])([H])N(C(=O)[C@@]([H])(C3=C([H])C(F)=C(C([H])=C3[H])C(F)(F)F)C([H])([H])N([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C2([H])[H])[C@]([H])(C([H])([H])[H])C1([H])[H]
[H]O[C@@]1([H])C2=C(C(=NC([H])=N2)N2C([H])([H])C([H])([H])N(C(=O)[C@@]([H])(C3=C([H])C(F)=C(Cl)C([H])=C3[H])C([H])([H])N([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C2([H])[H])[C@]([H])(C([H])([H])[H])C1([H])[H]
[H]O[C@@]1([H])C2=C(C(=NC([H])=N2)N2C([H])([H])C([H])([H])N(C(=O)[C@@]([H])(C3=C([H])C([H])=C(C([H])=C3[H])C(F)(F)F)C([H])([H])N([H])[H])C([H])([H])C2([H])[H])[C@]([H])(C([H])([H])[H])C1([H])[H]
[H]O[C@@]1([H])C2=C(C(=NC([H])=N2)N2C([H])([H])C([H])([H])N(C(=O)[C@@]([H])(C3=C([H])C([H])=C(Cl)C([H])=C3[H])[C@@]3([H])N([H])C([H])([H])C([H])([H])OC3([H])[H])C([H])([H])C2([H])[H])[C@]([H])(C([H])([H])[H])C1([H])[H]
[H]O[C@@]1([H])C2=C(C(=NC([H])=N2)N2C([H])([H])C([H])([H])N(C(=O)[C@@]([H])(C3=C([H])C([H])=C(Cl)C([H])=C3[H])[C@@]3([H])N([H])C([H])([H])C([H])([H])C([H])([H])C3([H])[H])C([H])([H])C2([H])[H])[C@]([H])(C([H])([H])[H])C1([H])[H]
[H]O[C@@]1([H])C2=C(C(=NC([H])=N2)N2C([H])([H])C([H])([H])N(C(=O)[C@@]([H])(C3=C([H])C([H])=C(Cl)C([H])=C3[H])C([H])([H])N([H])C([H])([H])C3([H])C([H])([H])C([H])([H])OC([H])([H])C3([H])[H])C([H])([H])C2([H])[H])[C@]([H])(C([H])([H])[H])C1([H])[H]
[H]O[C@@]1([H])C2=C(C(=NC([H])=N2)N2C([H])([H])C([H])([H])N(C(=O)[C@@]([H])(C3=C([H])C([H])=C(Cl)C([H])=C3[H])C([H])([H])N([H])[C@]3([H])C([H])([H])C([H])([H])[C@]([H])(OC([H])([H])[H])C([H])([H])C3([H])[H])C([H])([H])C2([H])[H])[C@]([H])(C([H])([H])[H])C1([H])[H]
[H]O[C@@]1([H])C2=C(C(=NC([H])=N2)N2C([H])([H])C([H])([H])N(C(=O)[C@@]([H])(C3=C([H])C([H])=C(Cl)C([H])=C3[H])C([H])([H])N([H])C3([H])C([H])([H])C([H])([H])OC([H])([H])C3([H])[H])C([H])([H])C2([H])[H])[C@]([H])(C([H])([H])[H])C1([H])[H]
[H]O[C@@]1([H])C2=C(C(=NC([H])=N2)N2C([H])([H])C([H])([H])N(C(=O)[C@@]([H])(C3=C([H])C([H])=C(Cl)C([H])=C3[H])[C@@]3([H])N([H])C([H])([H])C([H])([H])C3([H])[H])C([H])([H])C2([H])[H])[C@]([H])(C([H])([H])[H])C1([H])[H]
[H]O[C@@]1([H])C2=C(C(=NC([H])=N2)N2C([H])([H])C([H])([H])N(C(=O)[C@@]([H])(C3=C([H])C([H])=C(Cl)C([H])=C3[H])C([H])([H])N(C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C2([H])[H])[C@]([H])(C([H])([H])[H])C1([H])[H]
[H]O[C@@]1([H])C2=C(C(=NC([H])=N2)N2C([H])([H])C([H])([H])N(C(=O)[C@@]([H])(C3=C([H])C([H])=C(Cl)C([H])=C3[H])C([H])([H])N([H])C3([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C3([H])[H])C([H])([H])C2([H])[H])[C@]([H])(C([H])([H])[H])C1([H])[H]
[H]O[C@@]1([H])C2=C(C(=NC([H])=N2)N2C([H])([H])C([H])([H])N(C(=O)[C@@]([H])(C3=C([H])C([H])=C(Cl)C([H])=C3[H])C([H])([H])N3C([H])([H])C([H])([H])C([H])(F)C([H])([H])C3([H])[H])C([H])([H])C2([H])[H])[C@]([H])(C([H])([H])[H])C1([H])[H]
[H]OC([H])([H])C(N([H])C([H])([H])[C@@]([H])(C(=O)N1C([H])([H])C([H])([H])N(C2=NC([H])=NC3=C2[C@]([H])(C([H])([H])[H])C([H])([H])[C@@]3([H])O[H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C(Cl)C([H])=C1[H])(C([H])([H])[H])C([H])([H])[H]
[H]O[C@@]1([H])C2=C(C(=NC([H])=N2)N2C([H])([H])C([H])([H])N(C(=O)[C@@]([H])(C3=C([H])C([H])=C(Cl)C([H])=C3[H])C([H])([H])N([H])C([H])([H])C([H])([H])OC([H])([H])[H])C([H])([H])C2([H])[H])[C@]([H])(C([H])([H])[H])C1([H])[H]
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[H]N(C([H])([H])[C@@]([H])(C(=O)N1C([H])([H])C([H])([H])N(C2=NC([H])=NC3=C2[C@]([H])(C([H])([H])[H])C([H])([H])C3(F)F)C([H])([H])C1([H])[H])C1=C([H])C([H])=C(Cl)C([H])=C1[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C([H])([H])[C@@]([H])(C(=O)N1C([H])([H])C([H])([H])N(C2=NC([H])=NC3=C2[C@]([H])(C([H])([H])[H])C([H])([H])[C@]3([H])F)C([H])([H])C1([H])[H])C1=C([H])C([H])=C(Cl)C([H])=C1[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]O[C@]1([H])C2=C(C(=NC([H])=N2)N2C([H])([H])C([H])([H])N(C(=O)[C@@]([H])(C3=C([H])C([H])=C(Cl)C([H])=C3[H])C([H])([H])N([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C2([H])[H])[C@]([H])(C([H])([H])[H])C1([H])[H]
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[H]N(C([H])([H])[C@@]([H])(C(=O)N1C([H])([H])C([H])([H])N(C2=NC([H])=NC3=C2[C@]([H])(C([H])([H])F)C([H])([H])C3([H])[H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C(Cl)C([H])=C1[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]C([H])=C([H])[C@@]1([H])C2=C(N=C([H])N=C2N2C([H])([H])C([H])([H])N(C(=O)[C@@]([H])(C3=C([H])C([H])=C(Cl)C([H])=C3[H])C([H])([H])N([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]N(C([H])([H])[C@@]([H])(C(=O)N1C([H])([H])C([H])([H])N(C2=NC([H])=NC3=C2C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C3([H])[H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C(Cl)C([H])=C1[H])C([H])(C([H])([H])[H])C([H])([H])[H]
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CC(NC(=O)C1(N)CCN(CC1)C1=NC=NC2=C1C=CN2)C1=CC=CN=C1
CC(NC(=O)C1(N)CCN(CC1)C1=NC=NC2=C1C=CN2)C1=CC=C(F)C=C1
CC(NC(=O)C1(N)CCN(CC1)C1=NC=NC2=C1C=CN2)C1=CC=CC=C1
NC1(CCN(CC1)C1=NC=NC2=C1C=CN2)C(=O)NC(CC1=CC=CC=C1)C1=CC=C(Cl)C=C1
NC1(CCN(CC1)C1=NC=NC2=C1C=CN2)C(=O)NC(C1=CC=CC=C1)C1=CC=C(Cl)C=C1
CCC(NC(=O)C1(N)CCN(CC1)C1=NC=NC2=C1C=CN2)C1=CC=C(Cl)C=C1
C[C@H](NC(=O)C1(N)CCN(CC1)C1=NC=NC2=C1C=CN2)C1=CC=C(Cl)C=C1
[H]N([H])C1(C(=O)N([H])C([H])([H])C2=C([H])C([H])=C(Cl)C([H])=C2[H])C([H])([H])C([H])([H])N(C2=NC([H])=NC3=C2C([H])=C([H])N3[H])C([H])([H])C1([H])[H]
[H]O\N=C(/C(=O)N([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C(O[H])C(Br)=C1[H])C([H])([H])C1=C([H])C(=C(O[H])C(Br)=C1[H])C1=C([H])C(=C([H])C(Br)=C1O[H])C([H])([H])C(=N\O[H])\C(=O)N([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C(O[H])C(Br)=C1[H]
CN(C)C1CCC(CC1)NC1=C(C=NC(NC2=CC(Cl)=CC(Cl)=C2)=N1)C1=CC(C)=NO1