[H]N(C(=O)C1=NN(C(N2C([H])=C([H])C([H])=C2[H])=C1C([H])([H])[H])C1=C([H])C([H])=C(F)C([H])=C1F)C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C(=O)C1=NN(C(N2C(=C([H])C([H])=C2C([H])([H])[H])C([H])([H])[H])=C1C([H])([H])[H])C1=C([H])C([H])=C(F)C([H])=C1F
[H]C1=C(C(=O)C2([H])C(C([H])([H])[H])(C([H])([H])[H])C2(C([H])([H])[H])C([H])([H])[H])C2=C([H])C(C#N)=C([H])C([H])=C2N1C([H])([H])C1([H])C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]N(N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C(=O)C1=NN(C(N2C([H])=C([H])C([H])=C2[H])=C1C([H])([H])[H])C1=C([H])C([H])=C(F)C([H])=C1F
[H]N(N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C(=O)C1=NN(C(N2C([H])=C([H])C([H])=C2[H])=C1C([H])([H])[H])C1=C([H])C([H])=C(F)C([H])=C1F
[H]N(C(=O)C1=NN(C(N2C([H])=C([H])C([H])=C2[H])=C1C([H])([H])[H])C1=C([H])C([H])=C(F)C([H])=C1F)C([H])([H])C1=C([H])C(Cl)=C(Cl)C([H])=C1[H]
[H]C1=C(C(=O)C2([H])C(C([H])([H])[H])(C([H])([H])[H])C2(C([H])([H])[H])C([H])([H])[H])C2=C(C([H])=C(OC([H])([H])[H])C([H])=C2[H])N1C([H])([H])C1([H])C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]C1=C(C(=O)C2([H])C(C([H])([H])[H])(C([H])([H])[H])C2(C([H])([H])[H])C([H])([H])[H])C2=C(N1C([H])([H])C1([H])C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C(OC([H])([H])[H])=C([H])C([H])=C2[H]
[H]C1=C(C(=O)C2([H])C(C([H])([H])[H])(C([H])([H])[H])C2(C([H])([H])[H])C([H])([H])[H])C2=C(OC([H])([H])C3=C([H])C([H])=C([H])C([H])=C3[H])C([H])=C([H])C([H])=C2N1C([H])([H])C1([H])C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]C1=C(C(=O)C2([H])C(C([H])([H])[H])(C([H])([H])[H])C2(C([H])([H])[H])C([H])([H])[H])C2=C([H])C(OC([H])([H])C3=C([H])C([H])=C([H])C([H])=C3[H])=C([H])C([H])=C2N1C([H])([H])C1([H])C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]C1=C(C(=O)C2([H])C(C([H])([H])[H])(C([H])([H])[H])C2(C([H])([H])[H])C([H])([H])[H])C2=C([H])C([H])=C(OC([H])([H])C3=C([H])C([H])=C([H])C([H])=C3[H])C([H])=C2N1C([H])([H])C1([H])C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]C1=C(C(=O)C2([H])C(C([H])([H])[H])(C([H])([H])[H])C2(C([H])([H])[H])C([H])([H])[H])C2=C([H])C([H])=C([H])C(OC([H])([H])C3=C([H])C([H])=C([H])C([H])=C3[H])=C2N1C([H])([H])C1([H])C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]C1=C([H])C2=C([H])C([H])=C([H])C(C(=O)C3=C(N4C5=C3C([H])=C([H])C([H])=C5OC([H])([H])[C@@]4([H])C([H])([H])N3C([H])([H])C([H])([H])OC([H])([H])C3([H])[H])C([H])([H])[H])=C2C([H])=C1[H]
[H]C1=C([H])C2=C(C([H])=C1[H])C(C(=O)C1=C3C([H])=C([H])C([H])=C([H])C3=C([H])C([H])=C1[H])=C(N2C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])[H]
[H]C1=C(C(=O)C2=C(I)C([H])=C([H])C(=C2[H])[N+]([O-])=O)C2=C(C([H])=C([H])C([H])=C2[H])N1C([H])([H])[C@]1([H])N(C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]C1=C(C(=O)C2([H])C(C([H])([H])[H])(C([H])([H])[H])C2(C([H])([H])[H])C([H])([H])[H])C2=C(C([H])=C([H])C([H])=C2[H])N1C([H])([H])C1([H])C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]N(N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C(=O)C1=NN(C(N2C([H])=C([H])C([H])=C2[H])=C1C#N)C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]N(N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C(=O)C1=C(N2C([H])=C([H])C([H])=C2[H])N(N=C1C([H])([H])[H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]N(C(=O)C1=C(N2C([H])=C([H])C([H])=C2[H])N(N=C1C([H])([H])[H])C1=C([H])C([H])=C(Cl)C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C(Cl)C(Cl)=C1[H]
[H]N(N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C(=O)C1=NN(C(N2C([H])=C([H])C([H])=C2[H])=C1C([H])([H])[H])C1=C([H])C([H])=C(Cl)C([H])=C1Cl
[H]N(C(=O)C1=NN(C(N2C([H])=C([H])C([H])=C2[H])=C1C([H])([H])[H])C1=C([H])C([H])=C(Cl)C([H])=C1Cl)C([H])([H])C1=C([H])C(Cl)=C(Cl)C([H])=C1[H]
[H]N(C(=O)C1=NN(C(N2C(=C([H])C([H])=C2C([H])([H])[H])C([H])([H])[H])=C1C([H])([H])[H])C1=C([H])C([H])=C(Cl)C([H])=C1Cl)C([H])([H])C1=C([H])C(Cl)=C(Cl)C([H])=C1[H]
[H]N(C(=O)C1=NN(C(N2C(=C([H])C([H])=C2C([H])([H])[H])C([H])([H])[H])=C1C([H])([H])[H])C1=C([H])C([H])=C(Cl)C([H])=C1Cl)C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C(=O)C1=NN(C(N2C([H])=C([H])C([H])=C2[H])=C1C([H])([H])[H])C1=C([H])C([H])=C(Cl)C(Cl)=C1[H]
[H]N(C(=O)C1=NN(C(N2C([H])=C([H])C([H])=C2[H])=C1C([H])([H])[H])C1=C([H])C([H])=C(Cl)C(Cl)=C1[H])C([H])([H])C1=C([H])C(Cl)=C(Cl)C([H])=C1[H]
[H]N(C(=O)C1=NN(C(N2C([H])=C([H])C([H])=C2[H])=C1C([H])([H])[H])C1=C([H])C([H])=C(Cl)C(Cl)=C1[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C(=O)C1=NN(C(N2C(=C([H])C([H])=C2C([H])([H])[H])C([H])([H])[H])=C1C([H])([H])[H])C1=C([H])C([H])=C(Cl)C(Cl)=C1[H]
[H]N(C(=O)C1=NN(C(N2C(=C([H])C([H])=C2C([H])([H])[H])C([H])([H])[H])=C1C([H])([H])[H])C1=C([H])C([H])=C(Cl)C(Cl)=C1[H])C([H])([H])C1=C([H])C(Cl)=C(Cl)C([H])=C1[H]
[H]N(C(=O)C1=NN(C(N2C(=C([H])C([H])=C2C([H])([H])[H])C([H])([H])[H])=C1C([H])([H])[H])C1=C([H])C([H])=C(Cl)C(Cl)=C1[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]C1=C(C(=O)C2([H])C(C([H])([H])[H])(C([H])([H])[H])C2(C([H])([H])[H])C([H])([H])[H])C2=C([H])C(=C([H])C([H])=C2N1C([H])([H])C1([H])C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C(=O)OC([H])([H])[H]
[H]C1=C(C(=O)C2([H])C(C([H])([H])[H])(C([H])([H])[H])C2(C([H])([H])[H])C([H])([H])[H])C2=C([H])C(=C([H])C([H])=C2N1C([H])([H])C1([H])C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C1=C(C(=O)C2([H])C(C([H])([H])[H])(C([H])([H])[H])C2(C([H])([H])[H])C([H])([H])[H])C2=C([H])C([H])=C(C#N)C([H])=C2N1C([H])([H])C1([H])C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]N([H])C([H])([H])C1=C([H])C([H])=C2C(=C1[H])N(C([H])=C2C(=O)C1([H])C(C([H])([H])[H])(C([H])([H])[H])C1(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]C1=C(C(=O)C2([H])C(C([H])([H])[H])(C([H])([H])[H])C2(C([H])([H])[H])C([H])([H])[H])C2=C([H])C([H])=C(C([H])=C2N1C([H])([H])C1([H])C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C(=O)OC([H])([H])[H]
[H]C1=C(C(=O)C2([H])C(C([H])([H])[H])(C([H])([H])[H])C2(C([H])([H])[H])C([H])([H])[H])C2=C([H])C([H])=C(C([H])=C2N1C([H])([H])C1([H])C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C(=O)C1=NN(C(=C1C([H])([H])[H])C1=C([H])C([H])=C(Cl)C([H])=C1[H])C1=C([H])C([H])=C(Cl)C([H])=C1Cl
[H]N(N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C(=O)C1=NN(C(=C1C([H])([H])[H])C1=C([H])C([H])=C(I)C([H])=C1[H])C1=C([H])C([H])=C(Cl)C([H])=C1Cl
[H]N(C(=O)C1=NN(C(=C1[H])C1=C([H])C([H])=C(Cl)C(=C1[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H])[C@]1([H])C(C([H])([H])[H])(C([H])([H])[H])[C@]2([H])C([H])([H])C([H])([H])[C@@]1(C([H])([H])[H])C2([H])[H]
[H]OC1=C([H])C([H])=C2N(C([H])=C(C(=O)C3([H])C(C([H])([H])[H])(C([H])([H])[H])C3(C([H])([H])[H])C([H])([H])[H])C2=C1[H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]OC1=C([H])C([H])=C2C(=C1[H])N(C([H])=C2C(=O)C1([H])C(C([H])([H])[H])(C([H])([H])[H])C1(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]C1=C(C(=O)C2([H])C(C([H])([H])[H])(C([H])([H])[H])C2(C([H])([H])[H])C([H])([H])[H])C2=C([H])C(OC([H])([H])[H])=C([H])C([H])=C2N1C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]C1=C(C(=O)C2([H])C(C([H])([H])[H])(C([H])([H])[H])C2(C([H])([H])[H])C([H])([H])[H])C2=C([H])C([H])=C(OC([H])([H])[H])C([H])=C2N1C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]N(N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C(=O)C1=NN(C(=C1[H])N1C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C(=O)C1=NN(C(N2C([H])=C([H])C([H])=C2[H])=C1C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C(=O)C1=NN(C(N2C([H])=C([H])C([H])=C2[H])=C1C#N)C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)C1=NN(C(N2C([H])=C([H])C([H])=C2[H])=C1C#N)C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])C(Cl)=C(Cl)C([H])=C1[H]
[H]N(N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C(=O)C1=NN(C(=C1[H])N1C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]N(C(=O)C1=NN(C(=C1[H])N1C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C(Cl)C([H])=C1[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C(=O)C1=NN(C(N2C([H])=C([H])C([H])=C2[H])=C1C([H])([H])[H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]N(C(=O)C1=NN(C(N2C([H])=C([H])C([H])=C2[H])=C1C([H])([H])[H])C1=C([H])C([H])=C(Cl)C([H])=C1[H])C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]OC1=C([H])C([H])=C([H])C2=C1C(=C([H])N2C([H])([H])C1([H])C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C(=O)C1([H])C(C([H])([H])[H])(C([H])([H])[H])C1(C([H])([H])[H])C([H])([H])[H]
[H]OC1=C([H])C2=C(C([H])=C1[H])N(C([H])=C2C(=O)C1([H])C(C([H])([H])[H])(C([H])([H])[H])C1(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]N(C(=O)C1=NN(C(N2C([H])=C([H])C([H])=C2[H])=C1C([H])([H])[H])C1=C([H])C([H])=C(Cl)C([H])=C1Cl)C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C(=O)C1=NN(C(N2C(=C([H])C([H])=C2C([H])([H])[H])C([H])([H])[H])=C1C([H])([H])[H])C1=C([H])C([H])=C(Cl)C([H])=C1Cl
[H]N(C(=O)C1=NN(C(N2C(=C([H])C([H])=C2C([H])([H])[H])C([H])([H])[H])=C1C([H])([H])[H])C1=C([H])C([H])=C(F)C([H])=C1F)C([H])([H])C1=C([H])C(Cl)=C(Cl)C([H])=C1[H]
[H]N(C(=O)C1=NN(C(N2C(=C([H])C([H])=C2C([H])([H])[H])C([H])([H])[H])=C1C([H])([H])[H])C1=C([H])C([H])=C(F)C([H])=C1F)C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C(=O)C1=NN(C(N2C([H])=C([H])C([H])=C2[H])=C1C([H])([H])[H])C1=C(Cl)C([H])=C(Cl)C([H])=C1Cl
[H]N(C(=O)C1=NN(C(N2C([H])=C([H])C([H])=C2[H])=C1C([H])([H])[H])C1=C(Cl)C([H])=C(Cl)C([H])=C1Cl)C([H])([H])C1=C([H])C(Cl)=C(Cl)C([H])=C1[H]
[H]N(N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C(=O)C1=NN(C(N2C(=C([H])C([H])=C2C([H])([H])[H])C([H])([H])[H])=C1C([H])([H])[H])C1=C(Cl)C([H])=C(Cl)C([H])=C1Cl
[H]N(C(=O)C1=NN(C(N2C(=C([H])C([H])=C2C([H])([H])[H])C([H])([H])[H])=C1C([H])([H])[H])C1=C(Cl)C([H])=C(Cl)C([H])=C1Cl)C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]C1=C(C(=O)C2([H])C(C([H])([H])[H])(C([H])([H])[H])C2(C([H])([H])[H])C([H])([H])[H])C2=C([H])C(OC([H])([H])C3=C([H])C([H])=C([H])C([H])=C3[H])=C(OC([H])([H])[H])C([H])=C2N1C([H])([H])C1([H])C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]OC1=C(OC([H])([H])[H])C([H])=C2N(C([H])=C(C(=O)C3([H])C(C([H])([H])[H])(C([H])([H])[H])C3(C([H])([H])[H])C([H])([H])[H])C2=C1[H])C([H])([H])C1([H])C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]OC1=C(O[H])C([H])=C2C(=C1[H])N(C([H])=C2C(=O)C1([H])C(C([H])([H])[H])(C([H])([H])[H])C1(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]C1=C(C(=O)C2([H])C(C([H])([H])[H])(C([H])([H])[H])C2(C([H])([H])[H])C([H])([H])[H])C2=C([H])C3=C(OC([H])([H])O3)C([H])=C2N1C([H])([H])C1([H])C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]N([H])C1=C([H])C([H])=C2N(C([H])=C(C(=O)C3([H])C(C([H])([H])[H])(C([H])([H])[H])C3(C([H])([H])[H])C([H])([H])[H])C2=C1[H])C([H])([H])C1([H])C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]OC1=C([H])C2=C(C([H])=C1[H])C(=C([H])N2C([H])([H])C1([H])C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C(=O)C1([H])C(C([H])([H])[H])(C([H])([H])[H])C1(C([H])([H])[H])C([H])([H])[H]
[H]OC1=C([H])C([H])=C([H])C2=C1N(C([H])=C2C(=O)C1([H])C(C([H])([H])[H])(C([H])([H])[H])C1(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]C1=C(C(=O)C2([H])C(C([H])([H])[H])(C([H])([H])[H])C2(C([H])([H])[H])C([H])([H])[H])C2=C(C([H])=C([H])C([H])=C2OC([H])([H])[H])N1C([H])([H])C1([H])C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]C1=C(C(=O)C2([H])C(C([H])([H])[H])(C([H])([H])[H])C2(C([H])([H])[H])C([H])([H])[H])C2=C(C([H])=C([H])C(OC([H])([H])[H])=C2[H])N1C([H])([H])C1([H])C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]C1=C(C(=O)C2([H])C(C([H])([H])[H])(C([H])([H])[H])C2(C([H])([H])[H])C([H])([H])[H])C2=C([H])C(OC([H])([H])C3=C([H])C([H])=C([H])C([H])=C3[H])=C([H])C([H])=C2N1C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]C1=C(C(=O)C2([H])C(C([H])([H])[H])(C([H])([H])[H])C2(C([H])([H])[H])C([H])([H])[H])C2=C([H])C([H])=C(OC([H])([H])C3=C([H])C([H])=C([H])C([H])=C3[H])C([H])=C2N1C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]C1=C([H])C([H])=C2C(=C1[H])N(C(=C2C(=O)C1([H])C(C([H])([H])[H])(C([H])([H])[H])C1(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]C1=C(C(=O)C2([H])C(C([H])([H])[H])(C([H])([H])[H])C2(C([H])([H])[H])C([H])([H])[H])C2=C(C([H])=C([H])C([H])=C2N1C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])[N+]([O-])=O
[H]N([H])C1=C2C(=C([H])C([H])=C1[H])N(C([H])=C2C(=O)C1([H])C(C([H])([H])[H])(C([H])([H])[H])C1(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]N(C(=O)C([H])([H])[H])C1=C2C(=C([H])C([H])=C1[H])N(C([H])=C2C(=O)C1([H])C(C([H])([H])[H])(C([H])([H])[H])C1(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]N(C1=C2C(=C([H])C([H])=C1[H])N(C([H])=C2C(=O)C1([H])C(C([H])([H])[H])(C([H])([H])[H])C1(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])S(=O)(=O)C([H])([H])[H]
[H]OC([H])([H])C([H])([H])C([H])([H])C([H])([H])OC1=C([H])C([H])=C2N(C([H])=C(C(=O)C3([H])C(C([H])([H])[H])(C([H])([H])[H])C3(C([H])([H])[H])C([H])([H])[H])C2=C1[H])C([H])([H])C1([H])C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]C1=C(C(=O)C2([H])C(C([H])([H])[H])(C([H])([H])[H])C2(C([H])([H])[H])C([H])([H])[H])C2=C([H])C(OC([H])([H])C([H])([H])C([H])([H])C([H])([H])Br)=C([H])C([H])=C2N1C([H])([H])C1([H])C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]N([H])C([H])([H])C1=C([H])C([H])=C2N(C([H])=C(C(=O)C3([H])C(C([H])([H])[H])(C([H])([H])[H])C3(C([H])([H])[H])C([H])([H])[H])C2=C1[H])C([H])([H])C1([H])C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]OC([H])([H])C1=C([H])C([H])=C2N(C([H])=C(C(=O)C3([H])C(C([H])([H])[H])(C([H])([H])[H])C3(C([H])([H])[H])C([H])([H])[H])C2=C1[H])C([H])([H])C1([H])C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]C1=C(C(=O)C2([H])C(C([H])([H])[H])(C([H])([H])[H])C2(C([H])([H])[H])C([H])([H])[H])C2=C([H])C(=C([H])C([H])=C2N1C([H])([H])C1([H])C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C([H])([H])OC([H])([H])[H]
[H]C1=C(C(=O)C2([H])C(C([H])([H])[H])(C([H])([H])[H])C2(C([H])([H])[H])C([H])([H])[H])C2=C([H])C([H])=C([H])C([H])=C2N1C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]C1=C(C(=O)C2([H])C(C([H])([H])[H])(C([H])([H])[H])C2(C([H])([H])[H])C([H])([H])[H])C2=C(N1C([H])([H])C1([H])C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C(F)=C(F)C(F)=C2F
[H]C1=C(C(=O)C2([H])C(C([H])([H])[H])(C([H])([H])[H])C2(C([H])([H])[H])C([H])([H])[H])C2=C(C([H])=C([H])C(F)=C2[H])N1C([H])([H])C1([H])C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]C1=C(C(=O)C2([H])C(C([H])([H])[H])(C([H])([H])[H])C2(C([H])([H])[H])C([H])([H])[H])C2=C(C([H])=C([H])C(Cl)=C2[H])N1C([H])([H])C1([H])C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]C1=C(C(=O)C2([H])C(C([H])([H])[H])(C([H])([H])[H])C2(C([H])([H])[H])C([H])([H])[H])C2=C(C([H])=C([H])C(Br)=C2[H])N1C([H])([H])C1([H])C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]C1=C(C(=O)C2([H])C(C([H])([H])[H])(C([H])([H])[H])C2(C([H])([H])[H])C([H])([H])[H])C2=C(C([H])=C(Cl)C([H])=C2[H])N1C([H])([H])C1([H])C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]C1=C(C(=O)C2([H])C(C([H])([H])[H])(C([H])([H])[H])C2(C([H])([H])[H])C([H])([H])[H])C2=C(C([H])=C(Br)C([H])=C2[H])N1C([H])([H])C1([H])C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]C1=C(C(=O)C2([H])C(C([H])([H])[H])(C([H])([H])[H])C2(C([H])([H])[H])C([H])([H])[H])C2=C(C([H])=C(C([H])=C2[H])C([H])([H])[H])N1C([H])([H])C1([H])C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]C1=C(C(=O)C2([H])C(C([H])([H])[H])(C([H])([H])[H])C2(C([H])([H])[H])C([H])([H])[H])C2=C(C([H])=C(C([H])=C2[H])C(F)(F)F)N1C([H])([H])C1([H])C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]C1=C(C(=O)C2([H])C(C([H])([H])[H])(C([H])([H])[H])C2(C([H])([H])[H])C([H])([H])[H])C2=C(C([H])=C(C([H])=C2[H])S(=O)(=O)C([H])([H])[H])N1C([H])([H])C1([H])C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C2SC3=C(C([H])=C([H])C([H])=C3[H])C(=NC2=C1[H])C1=C([H])C([H])=C([H])C([H])=C1Cl)C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C2SC3=C(C([H])=C([H])C([H])=C3[H])C(=NC2=C1[H])C1=C([H])C([H])=C(F)C(Cl)=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]OC([H])([H])C([H])([H])N([H])C(=O)C([H])([H])C([H])([H])C([H])([H])C(\[H])=C(\[H])C([H])([H])C(\[H])=C(\[H])C([H])([H])C(\[H])=C(\[H])C([H])([H])C(\[H])=C(\[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]O[C@@]1([H])C([H])([H])[C@@]1([H])N([H])C(=O)C([H])([H])C([H])([H])C([H])([H])C(\[H])=C(\[H])C([H])([H])C(\[H])=C(\[H])C([H])([H])C(\[H])=C(\[H])C([H])([H])C(\[H])=C(\[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]OC([H])([H])C([H])([H])N([H])C(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C2SC3=C(C([H])=C([H])C([H])=C3[H])C(=NC2=C1[H])N1C([H])([H])C([H])([H])C(F)(F)C([H])([H])C1([H])[H])C([H])([H])C1=C([H])C(Cl)=C([H])C([H])=C1[H]
[H]O[C@]1([H])C([H])([H])[C@]1([H])N([H])C(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C(\[H])=C(\[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]C1=C([H])C([H])=C(N2N=C3C(=C2C2=C([H])C([H])=C(Cl)C([H])=C2[H])C([H])([H])C([H])([H])N(C3=O)C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C(Cl)=C1[H]
[H]C1=C([H])C([H])=C(N2N=C3C(=C2C2=C([H])C([H])=C(Cl)C([H])=C2[H])C([H])([H])C([H])([H])N(C3=O)C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C(Cl)=C1[H]
[H]C1=C([H])C([H])=C(N2N=C3C(=C2C2=C([H])C([H])=C(Cl)C([H])=C2[H])C([H])([H])C([H])([H])N(C3=O)C([H])([H])C(OC([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C(Cl)=C1[H]
[H]N(\C(=N/S(=O)(=O)C1=C([H])C([H])=C(Cl)C([H])=C1[H])N1N=C(C2=C([H])C([H])=C(Cl)C([H])=C2[H])[C@@]([H])(C2=C([H])C([H])=C([H])C([H])=C2[H])C1([H])[H])C([H])([H])[H]
[H]OC(=O)C1=C([H])C2=C(C([H])=C1[H])C(OC1=C([H])C(=C([H])C(OC(=O)C([H])([H])[H])=C21)C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]OC1=C([H])C(=C([H])C2=C1[C@]1([H])C([H])([H])C(=C([H])C([H])([H])[C@@]1([H])C(O2)(C([H])([H])[H])C([H])([H])[H])C([H])([H])O[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]OC1=C2C(OC(C3=C2C([H])=C(C([H])=C3[H])C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])=C([H])C(=C1[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]OC1=C2C(OC(=O)C3=C2C([H])=C(C([H])=C3[H])C([H])([H])[H])=C([H])C(=C1[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]OC1=C([H])C(=C([H])C2=C1C1=C(C([H])=C([H])C(=C1[H])C([H])([H])[H])C(O2)(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]OC1=C2C(OC(C3=C2C([H])=C(C([H])=C3[H])C([H])([H])O[H])(C([H])([H])[H])C([H])([H])[H])=C([H])C(=C1[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]OC1=C2C(OC(C([H])([H])[H])(C([H])([H])[H])[C@]3([H])C([H])([H])C([H])([H])C(=C([H])[C@@]23[H])C([H])([H])[H])=C([H])C(=C1[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]OC1=C2C(OC(C([H])([H])[H])(C([H])([H])[H])[C@]3([H])C([H])([H])C([H])=C(C([H])([H])O[H])C([H])([H])[C@@]23[H])=C([H])C(=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]OC(=O)C1=C([H])C2=C(C([H])=C1[H])C(OC1=C([H])C(=C([H])C(O[H])=C21)C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]OC1=C2C(OC(C3=C2C([H])=C(C([H])=C3[H])C([H])([H])O[H])(C([H])([H])[H])C([H])([H])[H])=C([H])C(=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]OC(=O)C1=C([H])C([H])([H])[C@]2([H])[C@@]([H])(C3=C(O[H])C([H])=C(C([H])=C3OC2(C([H])([H])[H])C([H])([H])[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C1([H])[H]
[H]C1=C2OC(C([H])([H])[H])(C([H])([H])[H])[C@@]3([H])C([H])([H])C([H])([H])C(=C([H])[C@@]3([H])C2=C2OC([H])([H])C([H])([H])C([H])([H])C2=C1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])[H]
[H]OC1=C([H])C(=C([H])C2=C1[C@]1([H])C([H])=C(C([H])([H])[H])C([H])([H])C([H])([H])[C@@]1([H])C(O2)(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]\C(=C1/C2=C([H])C([H])=C([H])C([H])=C2C(=C1C([H])([H])[H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C1=C([H])C([H])=C([H])C2=C([H])C([H])=C([H])C([H])=C12
[H]\C(=C1/C([H])=C(C2=C([H])C([H])=C([H])C([H])=C12)C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C1=C2C([H])=C([H])C([H])=C([H])C2=C([H])C([H])=C1[H]
[H]C1=C(C([H])=C2C3=C(OC(C2=C1[H])(C([H])([H])[H])C([H])([H])[H])C([H])=C(C([H])=C3OC([H])([H])[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C(=O)OC([H])([H])[H]
[H]OC([H])([H])C1=C([H])C([H])=C2C(=C1[H])C1=C(OC2(C([H])([H])[H])C([H])([H])[H])C([H])=C(C([H])=C1[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]OC1=C([H])C(=C([H])C([H])=C1C1=C([H])C(=C([H])C([H])=C1C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]OC([H])([H])C1=C([H])C([H])=C2C(=C1[H])C1=C(OC2(C([H])([H])[H])C([H])([H])[H])C([H])=C(C([H])=C1[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]OC1=C([H])C(=C([H])C2=C1C1=C([H])C(=C([H])C([H])=C1C(O2)(C([H])([H])[H])C([H])([H])[H])C(=O)OC([H])([H])[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]C1=C([H])C(=C([H])C2=C1C1=C([H])C(=C([H])C([H])=C1C(O2)(C([H])([H])[H])C([H])([H])[H])C(=O)OC([H])([H])[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]C1=C(C([H])=C2C3=C(OC(C2=C1[H])(C([H])([H])[H])C([H])([H])[H])C([H])=C(C([H])=C3OC([H])([H])[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C(=O)OC([H])([H])C([H])([H])C([H])([H])[H]
[H]C1=C([H])C(=C([H])C2=C1C1=C([H])C(=C([H])C([H])=C1C(O2)(C([H])([H])[H])C([H])([H])[H])C(=O)OC([H])([H])[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]C1=C([H])C(=C([H])C2=C1C1=C([H])C(=C([H])C([H])=C1C(O2)(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]OC1=C([H])C(=C([H])C([H])=C1C1=C([H])C(=C([H])C([H])=C1C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]C1=C(C([H])=C2C3=C(OC(C2=C1[H])(C([H])([H])[H])C([H])([H])[H])C([H])=C(C([H])=C3OC([H])([H])[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])[H]
[H]OC1=C([H])C(=C([H])C2=C1C1=C([H])C(=C([H])C([H])=C1C(O2)(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]\C(=C(/[H])C([H])([H])C(\[H])=C(\[H])C([H])([H])C([H])([H])C([H])([H])C(=O)OC([H])([H])C1=C([H])C([H])=C([H])O1)C([H])([H])C(\[H])=C(\[H])C([H])([H])C(\[H])=C(\[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]N(C(=O)C([H])([H])C([H])([H])C([H])([H])C(\[H])=C(\[H])C([H])([H])C(\[H])=C(\[H])C([H])([H])C(\[H])=C(\[H])C([H])([H])C(\[H])=C(\[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C1=C([H])OC([H])=C1[H]
[H]OC1=C([H])C(=C([H])C([H])=C1[C@]1([H])C([H])([H])[C@]([H])(O[H])C([H])([H])C([H])([H])[C@@]1([H])C([H])([H])C([H])([H])C([H])([H])O[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]\C(=C(/[H])C([H])([H])C(\[H])=C(\[H])C([H])([H])C([H])([H])C([H])([H])C(=O)OC([H])([H])[C@@]1([H])OC([H])([H])C([H])([H])C1([H])[H])C([H])([H])C(\[H])=C(\[H])C([H])([H])C(\[H])=C(\[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]\C(=C(/[H])C([H])([H])C(\[H])=C(\[H])C([H])([H])C([H])([H])C([H])([H])C(=O)OC([H])([H])C1=C([H])SC([H])=C1[H])C([H])([H])C(\[H])=C(\[H])C([H])([H])C(\[H])=C(\[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]\C(=C(/[H])C([H])([H])C(\[H])=C(\[H])C([H])([H])C([H])([H])C([H])([H])C(=O)OC([H])([H])[C@@]1([H])C([H])([H])OC([H])([H])C1([H])[H])C([H])([H])C(\[H])=C(\[H])C([H])([H])C(\[H])=C(\[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]\C(=C(/[H])C([H])([H])C(\[H])=C(\[H])C([H])([H])C([H])([H])C([H])([H])C(=O)OC([H])([H])C1=C([H])C([H])=C([H])S1)C([H])([H])C(\[H])=C(\[H])C([H])([H])C(\[H])=C(\[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]OC1=C([H])C([H])=C(N([H])C(=O)C([H])([H])C([H])([H])C([H])([H])C(\[H])=C(\[H])C([H])([H])C(\[H])=C(\[H])C([H])([H])C(\[H])=C(\[H])C([H])([H])C(\[H])=C(\[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])=C1[H]
[H]N(C(=O)C([H])([H])C([H])([H])C([H])([H])C(\[H])=C(\[H])C([H])([H])C(\[H])=C(\[H])C([H])([H])C(\[H])=C(\[H])C([H])([H])C(\[H])=C(\[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])S1
[H]N(C(=O)C([H])([H])C([H])([H])C([H])([H])C(\[H])=C(\[H])C([H])([H])C(\[H])=C(\[H])C([H])([H])C(\[H])=C(\[H])C([H])([H])C(\[H])=C(\[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])[C@@]1([H])OC([H])([H])C([H])([H])C1([H])[H]
[H]N(C(=O)C([H])([H])C([H])([H])C([H])([H])C(\[H])=C(\[H])C([H])([H])C(\[H])=C(\[H])C([H])([H])C(\[H])=C(\[H])C([H])([H])C(\[H])=C(\[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])O1
[H]\C(=C(/[H])C([H])([H])C(\[H])=C(\[H])C([H])([H])C([H])([H])C([H])([H])C(=O)OC([H])([H])C1=C([H])OC([H])=C1[H])C([H])([H])C(\[H])=C(\[H])C([H])([H])C(\[H])=C(\[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]N(C(=O)C([H])([H])C([H])([H])C([H])([H])C(\[H])=C(\[H])C([H])([H])C(\[H])=C(\[H])C([H])([H])C(\[H])=C(\[H])C([H])([H])C(\[H])=C(\[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])N1C([H])([H])[H]
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[H]N(C(=O)C1=C(N(C2=C(OC([H])([H])[H])C([H])=C([H])C([H])=C12)C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C([H])([H])[H])[C@]([H])(C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)C1=C([H])N(C2=C(OC([H])([H])[H])C([H])=C([H])C([H])=C12)C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])[C@]1([H])C([H])([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C([H])([H])C1(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)C1=C(N(C2=C(OC([H])([H])[H])C([H])=C([H])C([H])=C12)C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C([H])([H])[H])[C@@]1([H])[C@@]2(C([H])([H])[H])C([H])([H])C([H])([H])[C@]([H])(C2([H])[H])C1(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)[C@@]([H])(N([H])C(=O)C1=C(N(C2=C(OC([H])([H])[H])C([H])=C([H])C([H])=C12)C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H]
[H]OC1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[C@]([H])(N([H])C(=O)C(\[H])=C(/[H])C1=C([H])C(OC([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])=C(OC([H])([H])[H])C([H])=C1[H])C(=O)OC([H])([H])[H]
[H]ON([H])C(=O)C1=NN(C(=C1C([H])([H])[H])C1=C([H])C([H])=C(Cl)C([H])=C1[H])C1=C([H])C([H])=C(Cl)C([H])=C1Cl
[H]N(C(=O)C1=NN(C(=C1C([H])([H])[H])C1=C([H])C([H])=C(Cl)C([H])=C1[H])C1=C([H])C([H])=C(Cl)C([H])=C1Cl)C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N(N([H])C([H])([H])C([H])([H])C([H])([H])[H])C(=O)C1=NN(C(=C1C([H])([H])[H])C1=C([H])C([H])=C(Cl)C([H])=C1[H])C1=C([H])C([H])=C(Cl)C([H])=C1Cl
[H]N(C(=O)C1=NN(C(=C1C([H])([H])[H])C1=C([H])C([H])=C(Cl)C([H])=C1[H])C1=C([H])C([H])=C(Cl)C([H])=C1Cl)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]N(C(=O)C1=NN(C(=C1C([H])([H])[H])C1=C([H])C([H])=C(Cl)C([H])=C1[H])C1=C([H])C([H])=C(Cl)C([H])=C1Cl)C([H])(C([H])([H])[H])C([H])([H])[H]
[H]OC([H])([H])C([H])([H])N([H])C(=O)C1=NN(C(=C1C([H])([H])[H])C1=C([H])C([H])=C(Cl)C([H])=C1[H])C1=C([H])C([H])=C(Cl)C([H])=C1Cl
[H]N(C(=O)C1=NN(C(=C1C([H])([H])[H])C1=C([H])C([H])=C(Cl)C([H])=C1[H])C1=C([H])C([H])=C(Cl)C([H])=C1Cl)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]N(N([H])C([H])([H])[H])C(=O)C1=NN(C(=C1C([H])([H])[H])C1=C([H])C([H])=C(Cl)C([H])=C1[H])C1=C([H])C([H])=C(Cl)C([H])=C1Cl
[H]OC([H])([H])C([H])([H])C([H])([H])N([H])C(=O)C1=NN(C(=C1C([H])([H])[H])C1=C([H])C([H])=C(Cl)C([H])=C1[H])C1=C([H])C([H])=C(Cl)C([H])=C1Cl
[H]N(C(=O)C1=C(N(C2=C(OC([H])([H])[H])C([H])=C(Cl)C([H])=C12)C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C([H])([H])[H])[C@]1([H])[C@]2(C([H])([H])[H])C([H])([H])C([H])([H])[C@@]([H])(C2([H])[H])C1(C([H])([H])[H])C([H])([H])[H]
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[H]N(C(=O)C1=C(N(C2=C1C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C([H])([H])[H])[C@]([H])(C(=O)OC([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)C1=C(N(C2=C(OC([H])([H])[H])C([H])=C([H])C([H])=C12)C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C([H])([H])[H])[C@]([H])(C(=O)OC([H])([H])[H])C([H])([H])C1=C([H])SC([H])=N1
[H]N(C(=O)C1=C(N(C2=C(OC([H])([H])[H])C([H])=C([H])C([H])=C12)C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C([H])([H])[H])[C@]([H])(C1=C([H])C([H])=NO1)C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C(=O)C1=NN(C(=C1C([H])([H])[H])C1=C([H])C([H])=C(Cl)C([H])=C1[H])C1=C([H])C([H])=C(Cl)C([H])=C1Cl
[H]N(C(=O)C1=NN(C(=C1C([H])([H])[H])C1=C([H])C([H])=C(Cl)C([H])=C1[H])C1=C([H])C([H])=C(Cl)C([H])=C1Cl)C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]N(N([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C(=O)C1=NN(C(=C1C([H])([H])[H])C1=C([H])C([H])=C(Cl)C([H])=C1[H])C1=C([H])C([H])=C(Cl)C([H])=C1Cl
[H]N(C(=O)C1=C([H])N(C2=C(OC([H])([H])[H])C([H])=C([H])C([H])=C12)C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])[C@@]1([H])[C@@]2(C([H])([H])[H])C([H])([H])C([H])([H])[C@]([H])(C2([H])[H])C1(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)C1=C(N(C2=C(OC([H])([H])[H])C([H])=C([H])C([H])=C12)C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C([H])([H])[H])[C@]([H])(C1=NOC([H])=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)C1=C(N(C2=C(OC([H])([H])[H])C([H])=C([H])C([H])=C12)C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C([H])([H])[H])[C@]1([H])C([H])([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C([H])([H])C1(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)C1=C(N(C2=C1C([H])=C([H])C([H])=C2OC([H])([H])[H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C([H])([H])[H])[C@]([H])(C(=O)OC([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)C1=C(N(C2=C(OC([H])([H])[H])C([H])=C([H])C([H])=C12)C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C([H])([H])[H])[C@]([H])(C(=O)OC([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])S1
[H]N(C(=O)C1=C(N(C2=C(OC([H])([H])[H])C([H])=C([H])C([H])=C12)C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C([H])([H])[H])[C@]([H])(C(=N\OC([H])([H])[H])\C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)C1=C([H])N(C2=C(OC([H])([H])[H])C([H])=C([H])C([H])=C12)C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])[C@@]([H])(C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)C1=C(N(C2=C(OC([H])([H])[H])C([H])=C([H])C([H])=C12)C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C([H])([H])[H])[C@]1([H])C([H])([H])C([H])([H])C([H])([H])C1(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)C(\[H])=C(/[H])C1=C([H])C(OC([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])=C(OC([H])([H])[H])C([H])=C1[H])[C@]([H])(C(=O)OC([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)C1=C(N(C2=C(OC([H])([H])[H])C([H])=C([H])C([H])=C12)C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C([H])([H])[H])[C@]([H])(C(=O)C([H])([H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(\C(=N/C([H])(C([H])([H])[H])C([H])([H])[H])N1N=C(C2=C([H])C([H])=C(Cl)C([H])=C2[H])[C@@]([H])(C2=C([H])C([H])=C([H])C([H])=C2[H])C1([H])[H])S(=O)(=O)N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H]
[H]N(\C(=N/C([H])([H])C([H])([H])[H])N1N=C(C2=C([H])C([H])=C(Cl)C([H])=C2[H])[C@@]([H])(C2=C([H])C([H])=C([H])C([H])=C2[H])C1([H])[H])S(=O)(=O)N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H]
[H]N(\C(=N/C([H])([H])[H])N1N=C(C2=C([H])C([H])=C(Cl)C([H])=C2[H])[C@@]([H])(C2=C([H])C([H])=C([H])C([H])=C2[H])C1([H])[H])S(=O)(=O)N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(\C(=N/C([H])([H])[H])N1N=C(C2=C([H])C([H])=C(Cl)C([H])=C2[H])[C@]([H])(C2=C([H])N=C([H])C([H])=C2[H])C1([H])[H])S(=O)(=O)N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H]
[H]N(\C(=N/S(=O)(=O)N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])N1N=C(C2=C([H])C([H])=C(Cl)C([H])=C2[H])[C@@]([H])(C2=C([H])C([H])=C([H])C([H])=C2[H])C1([H])[H])C([H])([H])[H]
[H]N(\C(=N/C([H])([H])[H])N1N=C(C2=C([H])C([H])=C(Cl)C([H])=C2[H])[C@@]([H])(C2=C([H])C([H])=C([H])C([H])=C2[H])C1([H])[H])S(=O)(=O)N(C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)C1=NN(C2=C(OC([H])([H])[H])C([H])=C([H])C([H])=C12)C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])[C@@]([H])(C1=C([H])C([H])=C([H])C([H])=N1)C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)C1=C(N(C2=C(OC([H])([H])[H])C([H])=C([H])C([H])=C12)C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C([H])([H])C([H])([H])[H])[C@@]1([H])[C@@]2(C([H])([H])[H])C([H])([H])C([H])([H])[C@]([H])(C2([H])[H])C1(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)C1=NN(C2=C(OC([H])([H])[H])C([H])=C([H])C([H])=C12)C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1OC([H])([H])[H]
[H]C1=C([H])C(OC([H])([H])[H])=C2N(C3=C(C2=C1[H])C(=O)N(C([H])=C3[H])[C@]1([H])C(C([H])([H])[H])(C([H])([H])[H])[C@@]2([H])C([H])([H])C([H])([H])[C@@]1(C([H])([H])[H])C2([H])[H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]C1=C([H])C(OC([H])([H])[H])=C2N(N=C(C(=O)N(C([H])([H])C3=C(F)C([H])=C([H])C([H])=C3Cl)C([H])(C([H])([H])[H])C([H])([H])[H])C2=C1[H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]C1=C([H])C([H])=C(C(OC([H])([H])[H])=C1[H])C([H])([H])N1C([H])=C([H])C2=C(C3=C([H])C([H])=C([H])C(OC([H])([H])[H])=C3N2C([H])([H])C([H])([H])N2C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])C1=O
[H]N(C(=O)C1=NN(C2=C(OC([H])([H])[H])C([H])=C([H])C([H])=C12)C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])[C@@]1([H])[C@@]2(C([H])([H])[H])C([H])([H])C([H])([H])[C@]([H])(C2([H])[H])C1(C([H])([H])[H])C([H])([H])[H]
[H]N(\C(=N/C([H])([H])[H])N1N=C(C2=C([H])C([H])=C(Cl)C([H])=C2[H])[C@]([H])(C2=C([H])C([H])=C([H])C([H])=C2[H])C1([H])[H])S(=O)(=O)N1C([H])([H])C([H])([H])SC([H])([H])C1([H])[H]
[H]N(\C(=N/C([H])([H])[H])N1N=C(C2=C([H])C([H])=C(Cl)C([H])=C2[H])[C@]([H])(C2=C([H])C([H])=C([H])C([H])=C2[H])C1([H])[H])S(=O)(=O)N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(\C(=N/C([H])([H])[H])N1N=C(C2=C([H])C([H])=C(Cl)C([H])=C2[H])[C@@]([H])(C2=C([H])C([H])=C([H])C([H])=C2[H])C1([H])[H])S(=O)(=O)N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H]
[H]N(\C(=N/C([H])([H])[H])N1N=C(C2=C([H])C([H])=C(Cl)C([H])=C2[H])[C@]([H])(C2=C([H])C([H])=C([H])C([H])=C2[H])C1([H])[H])S(=O)(=O)N(C([H])([H])[H])C([H])([H])[H]
[H]N(\C(=N/C([H])([H])[H])N1N=C(C2=C([H])C([H])=C(Cl)C([H])=C2[H])[C@]([H])(C2=C([H])C([H])=C([H])C([H])=C2[H])C1([H])[H])S(=O)(=O)N(C([H])([H])[H])C([H])([H])C([H])([H])[H]
[H]N(\C(=N/C([H])([H])[H])N1N=C(C2=C([H])C([H])=C(Cl)C([H])=C2[H])[C@@]([H])(C2=C([H])C([H])=C([H])C([H])=C2[H])C1([H])[H])S(=O)(=O)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]N(\C(=N/C([H])([H])[H])N1N=C(C2=C([H])C([H])=C(Cl)C([H])=C2[H])[C@]([H])(C2=C([H])C([H])=C([H])C([H])=C2[H])C1([H])[H])S(=O)(=O)N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(\C(=N/C([H])([H])[H])N1N=C(C2=C([H])C([H])=C(Cl)C([H])=C2[H])[C@]([H])(C2=C([H])C([H])=C([H])C([H])=C2[H])C1([H])[H])S(=O)(=O)N1C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(C(=O)C1=NN(C(=C1C([H])([H])[H])C1=C([H])C([H])=C(Cl)C([H])=C1[H])C1=C([H])C([H])=C(Cl)C([H])=C1Cl)C([H])([H])C([H])([H])[H]
[H]OC([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=O)C1=NN(C(=C1C([H])([H])[H])C1=C([H])C([H])=C(Cl)C([H])=C1[H])C1=C([H])C([H])=C(Cl)C([H])=C1Cl
[H]N(N([H])C([H])([H])C([H])([H])[H])C(=O)C1=NN(C(=C1C([H])([H])[H])C1=C([H])C([H])=C(Cl)C([H])=C1[H])C1=C([H])C([H])=C(Cl)C([H])=C1Cl
[H]OC1=C([H])C(=C([H])C2=C1[C@]1([H])C([H])([H])C(=C([H])C([H])([H])[C@@]1([H])C(O2)(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C(C([H])([H])[H])(C([H])([H])[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]OC1=C([H])C(=C([H])C2=C1[C@]1([H])C([H])([H])C(=C([H])C([H])([H])[C@@]1([H])C(O2)(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C(=O)C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC1=C([H])C(=C([H])C2=C1[C@]1([H])C([H])([H])C(=C([H])C([H])([H])[C@@]1([H])C(O2)(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C(C1=C([H])C([H])=C([H])C([H])=C1[H])(C([H])([H])[H])C([H])([H])[H]
[H]OC1=C([H])C(=C([H])C2=C1[C@]1([H])C([H])([H])C(=C([H])C([H])([H])[C@@]1([H])C(O2)(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C1(SC([H])([H])C([H])([H])S1)C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]OC1=C([H])C(=C([H])C2=C1[C@]1([H])C([H])([H])C(=C([H])C([H])([H])[C@@]1([H])C(O2)(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC1=C([H])C(=C([H])C2=C1[C@]1([H])C([H])([H])C(=C([H])C([H])([H])[C@@]1([H])C(O2)(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C1(SC([H])([H])C([H])([H])S1)C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])[C@@]1([H])C(=NN(\C(SC([H])([H])[H])=N\S(=O)(=O)C2=C([H])C([H])=C(C([H])=C2[H])C(F)(F)F)C1([H])[H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])[C@@]1([H])C(=NN(\C(=N\S(=O)(=O)C2=C([H])C([H])=C(Cl)C([H])=C2[H])N(C([H])([H])[H])C([H])([H])[H])C1([H])[H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]N=C(N([H])S(=O)(=O)C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])N1N=C(C2=C([H])C([H])=C(Cl)C([H])=C2[H])[C@@]([H])(C2=C([H])C([H])=C([H])C([H])=C2[H])C1([H])[H]
[H]N(\C(=N/C([H])([H])[H])N1N=C(C2=C([H])C([H])=C(Cl)C([H])=C2[H])[C@]([H])(C2=C([H])C([H])=C([H])C([H])=C2[H])C1([H])[H])S(=O)(=O)C1=C([H])C(=C([H])C([H])=C1[H])C(F)(F)F
[H]N(\C(=N/C([H])([H])[H])N1N=C(C2=C([H])C([H])=C(Cl)C([H])=C2[H])[C@]([H])(C2=C([H])C([H])=C([H])C([H])=C2[H])C1([H])[H])S(=O)(=O)C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]N=C(N([H])S(=O)(=O)C1=C(C([H])=C(C([H])=C1C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])N1N=C(C2=C([H])C([H])=C(Cl)C([H])=C2[H])[C@@]([H])(C2=C([H])C([H])=C([H])C([H])=C2[H])C1([H])[H]
[H]N=C(N([H])S(=O)(=O)C1=C([H])C([H])=C(F)C([H])=C1[H])N1N=C(C2=C([H])C([H])=C(Cl)C([H])=C2[H])[C@]([H])(C2=C([H])C([H])=C([H])C([H])=C2[H])C1([H])[H]
[H]N(\C(=N/C([H])([H])[H])N1N=C(C2=C([H])C([H])=C(Cl)C([H])=C2[H])[C@]([H])(C2=C([H])C([H])=C([H])C([H])=C2[H])C1([H])[H])S(=O)(=O)C1=C([H])C([H])=C(C([H])=C1[H])C(F)(F)F
[H]N=C(N([H])S(=O)(=O)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H])N1N=C(C2=C([H])C([H])=C(Cl)C([H])=C2[H])[C@@]([H])(C2=C([H])C([H])=C([H])C([H])=C2[H])C1([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])[C@]1([H])C(=NN(\C(=N\S(=O)(=O)C2=C([H])C([H])=C(F)C([H])=C2[H])N(C([H])([H])[H])C([H])([H])[H])C1([H])[H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]N(\C(=N/C([H])([H])[H])N1N=C(C2=C([H])C([H])=C(Cl)C([H])=C2[H])[C@@]([H])(C2=C([H])C([H])=C([H])C([H])=C2[H])C1([H])[H])S(=O)(=O)C1=C([H])C([H])=C([H])C(Cl)=C1[H]
[H]N=C(N([H])S(=O)(=O)C1=C([H])C([H])=C(Cl)C([H])=C1[H])N1N=C(C2=C([H])C([H])=C(Cl)C([H])=C2[H])[C@]([H])(C2=C([H])C([H])=C([H])C([H])=C2[H])C1([H])[H]
[H]N(\C(=N/C([H])([H])[H])N1N=C(C2=C([H])C([H])=C(Cl)C([H])=C2[H])[C@@]([H])(C2=C([H])C([H])=C([H])C([H])=C2[H])C1([H])[H])S(=O)(=O)C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]N(\C(=N/C([H])([H])[H])N1N=C(C2=C([H])C([H])=C(Cl)C([H])=C2[H])[C@@]([H])(C2=C([H])C([H])=C([H])C([H])=C2[H])C1([H])[H])S(=O)(=O)C1=C([H])C([H])=C([H])C([H])=C1Cl
[H]N(C(=O)C1=C(OC([H])([H])C2=C([H])C(F)=C(F)C([H])=C2[H])N=C(C2=C([H])C([H])=C(Cl)C([H])=C2Cl)C(=C1[H])C1=C([H])C([H])=C(Cl)C([H])=C1[H])C([H])([H])C([H])([H])[H]
[H]C1=C([H])C(=C([H])C([H])=C1Cl)C1=C([H])C(C#N)=C(OC([H])([H])C2=C([H])C(F)=C(F)C([H])=C2[H])N=C1C1=C([H])C([H])=C(Cl)C([H])=C1Cl
[H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])OC1=C(C#N)C([H])=C(C(=N1)C1=C([H])C([H])=C(Cl)C([H])=C1Cl)C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]OC1=C([H])C(OC([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C(=O)N([H])C([H])([H])C([H])([H])O[H])=C(C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]OC1=C([H])C(=C([H])C(OC([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C(=O)N([H])C2([H])C([H])([H])C2([H])[H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]OC1=C([H])C(OC([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C(=O)N([H])C2([H])C([H])([H])C2([H])[H])=C([H])C(=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]OC1=C(C([H])=C([H])C(OC([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C(=O)N([H])C([H])([H])C([H])([H])O[H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]OC1=NC2=C(C([H])=C([H])C(OC([H])([H])[H])=C2OC([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])=C1C(=O)N([H])C([H])([H])C1=C([H])C([H])=C2OC([H])([H])OC2=C1[H]
[H]C1=C2C(=C([H])C(I)=C1[H])N(C(=C2C(=O)C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])C([H])([H])[H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]N(C(=O)C1=C(OC([H])([H])C2=C([H])C(F)=C(F)C([H])=C2[H])N=C(C2=C([H])C([H])=C(Cl)C([H])=C2Cl)C(=C1[H])C1=C([H])C([H])=C(Cl)C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]N(N1C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C(=O)C1=C(N(C(=N1)C1=C(Cl)C([H])=C(Cl)C([H])=C1[H])C1=C([H])C([H])=C(Cl)C([H])=C1[H])C([H])([H])[H]
[H]N(N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C(=O)C1=C(N(C(=N1)C1=C(Cl)C([H])=C(Cl)C([H])=C1[H])C1=C([H])C([H])=C(Cl)C([H])=C1[H])C([H])([H])C([H])([H])[H]
[H]N(N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C(=O)C1=C([H])N(C(=N1)C1=C([H])C([H])=C(Cl)C([H])=C1Cl)C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]N(N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C(=O)C1=NN(C(=N1)C1=C([H])C([H])=C(Cl)C([H])=C1[H])C1=C([H])C([H])=C(Cl)C([H])=C1Cl
[H]N(C(=O)C1=C(N(C(=N1)C1=C(Cl)C([H])=C(Cl)C([H])=C1[H])C1=C([H])C([H])=C(Cl)C([H])=C1[H])C([H])([H])[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]C1=C([H])C2=C(C([H])=C1[H])C([H])([H])C([H])([H])N(C(=O)C1=C(N(C(=N1)C1=C(Cl)C([H])=C(Cl)C([H])=C1[H])C1=C([H])C([H])=C(Cl)C([H])=C1[H])C([H])([H])[H])C2([H])[H]
[H]N(N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C(=O)C1=NC(=C(S1)C1=C([H])C([H])=C(Cl)C([H])=C1[H])C1=C(Cl)C([H])=C(Cl)C([H])=C1[H]
[H]N(N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C(=O)C1=C(N(C(=N1)C1=C(Cl)C([H])=C(Cl)C([H])=C1[H])C1=C([H])C([H])=C(Cl)C([H])=C1[H])C([H])([H])[H]
[H]N(N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C(=O)C1=C(N(C(=N1)C1=C(Cl)C([H])=C(Cl)C([H])=C1[H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])C([H])([H])[H]
[H]N(N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C(=O)C1=NN(C(=N1)C1=C(Cl)C([H])=C(Cl)C([H])=C1[H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]N(OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C(=O)C1=C(N(C(=N1)C1=C(Cl)C([H])=C(Cl)C([H])=C1[H])C1=C([H])C([H])=C(Cl)C([H])=C1[H])C([H])([H])[H]
[H]N(C(=O)C1=C(N(C(=N1)C1=C(Cl)C([H])=C(Cl)C([H])=C1[H])C1=C([H])C([H])=C(Cl)C([H])=C1[H])C([H])([H])[H])[C@]1([H])C([H])([H])[C@@]2([H])C([H])([H])C([H])([H])[C@]1([H])C2([H])[H]
[H]C1=C([H])C(=C([H])C([H])=C1Cl)N1C(=NC(C(=O)N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H])=C1C([H])([H])[H])C1=C(Cl)C([H])=C(Cl)C([H])=C1[H]
[H]N(N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C(=O)C1=C(N(C(=N1)C1=C(Cl)C([H])=C(Cl)C([H])=C1[H])C1=C([H])C([H])=C(Cl)C([H])=C1[H])C([H])([H])[H]
[H]N(N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C(=O)C1=C(N(C(=N1)C1=C(Cl)C([H])=C(Cl)C([H])=C1[H])C1=C([H])C([H])=C(Cl)C([H])=N1)C([H])([H])[H]
[H]N(N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C(=O)C1=C(N(C(=N1)C1=C(Cl)C([H])=C(Cl)C([H])=C1[H])C1=C([H])C([H])=C(Cl)C([H])=C1[H])C([H])([H])[H]
[H]N(N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C(=O)C1=C(N(C(=N1)C1=C(Cl)C([H])=C(Cl)C([H])=C1[H])C1=C([H])C([H])=C(Cl)C([H])=C1[H])C([H])([H])F
[H]N(N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C(=O)C1=C(N(C(=N1)C1=C(Cl)C([H])=C(Cl)C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C(F)(F)F)C([H])([H])[H]
[H]N(C(=O)C1=C(N(C(=N1)C1=C(Cl)C([H])=C(Cl)C([H])=C1[H])C1=C([H])C([H])=C(Cl)C([H])=C1[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C(F)(F)F
[H]N(C(=O)C1=C(N(C(=N1)C1=C(Cl)C([H])=C(Cl)C([H])=C1[H])C1=C([H])C([H])=C(Cl)C([H])=C1[H])C([H])([H])[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C(=O)C1=C(Br)N(C(=N1)C1=C(Cl)C([H])=C(Cl)C([H])=C1[H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]O[C@@]1([H])C([H])([H])C([H])([H])[C@]([H])(N([H])C(=O)C2=C(N(C(=N2)C2=C(Cl)C([H])=C(Cl)C([H])=C2[H])C2=C([H])C([H])=C(Cl)C([H])=C2[H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]OC1([H])C([H])([H])C([H])([H])N(C(=O)C2=C(N(C(=N2)C2=C(Cl)C([H])=C(Cl)C([H])=C2[H])C2=C([H])C([H])=C(Cl)C([H])=C2[H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N(N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C(=O)C1=C(N(C(=N1)C1=C(Cl)C([H])=C(Cl)C([H])=C1[H])C1=C([H])C([H])=C(F)C([H])=C1[H])C([H])([H])[H]
[H]C1=C([H])C(=C([H])C([H])=C1Cl)N1C(=NC(C(=O)OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])=C1C([H])([H])[H])C1=C(Cl)C([H])=C(Cl)C([H])=C1[H]
[H]C1=C(C(=O)C([H])([H])C2=C([H])C(F)=C([H])C([H])=C2[H])C2=C([H])C([H])=C([H])C([H])=C2N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]C1=C([H])C([H])=C2C(=C1[H])N(C(=C2C(=O)C([H])([H])C1=C(OC([H])([H])[H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]C1=C([H])C([H])=C2C(=C1[H])N(C(=C2C(=O)C([H])([H])C1=C([H])C([H])=C(F)C([H])=C1[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]N(N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C(=O)C1=NC(=C(S1)C1=C([H])C([H])=C(Cl)C([H])=C1Cl)C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]N(N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C(=O)C1=C(Cl)N(C(=N1)C1=C(Cl)C([H])=C(Cl)C([H])=C1[H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]N(N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C(=O)C1=C(C#N)N(C(=N1)C1=C(Cl)C([H])=C(Cl)C([H])=C1[H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]N(N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C(=O)C1=C(N(C(=N1)C1=C([H])C([H])=C(Cl)C([H])=C1[H])C1=C(Cl)C([H])=C(Cl)C([H])=C1[H])C([H])([H])[H]
[H]N(N1C([H])([H])[C@@]2([H])C([H])([H])C([H])([H])C([H])([H])[C@@]2([H])C1([H])[H])C(=O)C1=C(N(C(=N1)C1=C([H])C([H])=C(Cl)C([H])=C1Cl)C1=C([H])C([H])=C(Cl)C([H])=C1[H])C([H])([H])[H]
[H]N(N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C(=O)C1=C(N(C(=N1)C1=C(Cl)C([H])=C(Cl)C([H])=C1[H])C1=C([H])C([H])=C(Br)C([H])=C1[H])C([H])([H])[H]
[H]OC1=C(C([H])=C([H])C(OC([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C(=O)N([H])C2([H])C([H])([H])C2([H])[H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]OC1=C([H])C(OC([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C(=O)N([H])C2([H])C([H])([H])C2([H])[H])=C(C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]N(N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C(=O)C1=NN(C(=C1C([H])([H])C([H])([H])[H])C1=C([H])C([H])=C(Br)C([H])=C1[H])C1=C([H])C([H])=C(Cl)C([H])=C1Cl
[H]C1=C([H])C([H])=C2C(=C1[H])N(C(=C2C(=O)C([H])([H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]C1=C(C(=O)C([H])([H])C2=C([H])C([H])=C(OC([H])([H])[H])C([H])=C2[H])C2=C([H])C([H])=C([H])C([H])=C2N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]C1=C([H])C([H])=C2C(=C1[H])N(C(=C2C(=O)C([H])([H])C1=C(F)C([H])=C([H])C([H])=C1[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]C1=C([H])C([H])=C2C(=C1[H])N(C(=C2C(=O)C([H])([H])C1=C(Cl)C([H])=C([H])C([H])=C1[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]C1=C([H])C([H])=C2C(=C1[H])N(C(=C2C(=O)C([H])([H])C1=C([H])C(Cl)=C([H])C([H])=C1[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]C1=C([H])C([H])=C2C(=C1[H])N(C(=C2C(=O)C([H])([H])C1=C(C([H])=C([H])C([H])=C1[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]C1=C(C(=O)C([H])([H])C2=C(Cl)C([H])=C([H])C([H])=C2[H])C2=C([H])C([H])=C([H])C([H])=C2N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]N(C(=O)C([H])([H])[N+]([H])([H])[H])C1=C([H])C2=C(C([H])=C([H])C([H])=C2[H])C(=C1[H])C(=O)C1=C(N(C2=C([H])C([H])=C([H])C([H])=C12)C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])C([H])=C2C(=C1[H])N(C(=C2C(=O)C1=C([H])C(=C([H])C2=C1C([H])=C([H])C([H])=C2[H])[N+]([O-])=O)C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[H]
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[H]N(C(=O)C([H])([H])[H])C1=C(C(=O)C([H])([H])[H])C(=O)N(C2=C1C([H])=C(C1=C([H])C([H])=C(Cl)C([H])=C1[H])C(=N2)C1=C([H])C([H])=C(Cl)C([H])=C1Cl)C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)C([H])([H])[H])C1=C(OC([H])([H])[H])C(=O)N(C2=C1C([H])=C(C1=C([H])C([H])=C(Cl)C([H])=C1[H])C(=N2)C1=C([H])C([H])=C(Cl)C([H])=C1Cl)C([H])([H])[H]
[H]N(C(=O)C([H])([H])[H])C1=C(C(=O)C([H])([H])[H])C(=O)N(C2=NC(C3=C([H])C([H])=C(Cl)C([H])=C3Cl)=C(C([H])=C12)C1=C([H])C([H])=C(Cl)C([H])=C1[H])C([H])([H])[H]
[H]N(C(=O)C([H])([H])[H])C1=C(C(=O)N(C2=C1C([H])=C(C1=C([H])C([H])=C(Cl)C([H])=C1[H])C(=N2)C1=C([H])C([H])=C(Cl)C([H])=C1Cl)C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)C([H])([H])[H])C1=C(C(=O)N(C2=C1C([H])=C(C1=C([H])C([H])=C(Cl)C([H])=C1[H])C(=N2)C1=C([H])C([H])=C(Cl)C([H])=C1Cl)C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)C([H])([H])[H])C1=C(N(C([H])([H])[H])C([H])([H])[H])C(=O)N(C2=C1C([H])=C(C1=C([H])C([H])=C(Cl)C([H])=C1[H])C(=N2)C1=C([H])C([H])=C(Cl)C([H])=C1Cl)C([H])([H])[H]
[H]C1=C([H])C(=C([H])C([H])=C1Cl)C1=C(N=C2N(C(=O)C(C(=O)C([H])([H])[H])=C(C2=C1[H])C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C(Cl)C([H])=C1Cl
[H]OC([H])([H])C([H])([H])N1C(=O)C(C(=O)C([H])([H])[H])=C(N([H])C(=O)C([H])([H])[H])C2=C1N=C(C1=C([H])C([H])=C(Cl)C([H])=C1Cl)C(=C2[H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]OC([H])([H])C(=O)N([H])C1=C(C(=O)C([H])([H])[H])C(=O)N(C2=C1C([H])=C(C1=C([H])C([H])=C(Cl)C([H])=C1[H])C(=N2)C1=C([H])C([H])=C(Cl)C([H])=C1Cl)C([H])([H])[H]
[H]N([C@]([H])(C1=C([H])C([H])=C(C([H])=C1[H])C(=O)C1=C(C([H])=C(Cl)C([H])=C1[H])S(=O)(=O)C1=C([H])C([H])=C(Cl)C([H])=C1[H])C([H])([H])[H])S(=O)(=O)C([H])([H])[H]
[H]N([C@]([H])(C1=C([H])C([H])=C(C([H])=C1[H])C(=N/OC([H])([H])[H])\C1=C(C([H])=C(Cl)C([H])=C1[H])S(=O)(=O)C1=C([H])C([H])=C(Cl)C([H])=C1[H])C([H])([H])[H])S(=O)(=O)C([H])([H])[H]
[H]N([C@]([H])(C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C1=C(C([H])=C(Cl)C([H])=C1[H])S(=O)(=O)C1=C([H])C([H])=C(Cl)C([H])=C1[H])C([H])([H])[H])S(=O)(=O)C([H])([H])[H]
[H]N([C@]([H])(C1=C([H])C([H])=C(C([H])=C1[H])C(=O)C1=C(C([H])=C(OC(F)(F)F)C([H])=C1[H])S(=O)(=O)C1=C([H])C([H])=C([H])C([H])=C1F)C([H])([H])[H])S(=O)(=O)C([H])([H])[H]
[H]N([C@]([H])(C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)C1=C(C([H])=C(OC([H])([H])[H])C([H])=C1[H])S(=O)(=O)C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H])S(=O)(=O)C([H])([H])[H]
[H]N([C@]([H])(C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)C1=C(C([H])=C([H])C([H])=C1[H])S(=O)(=O)C1=C([H])C([H])=C(Cl)C([H])=C1[H])C([H])([H])[H])S(=O)(=O)C([H])([H])[H]
[H]N([C@]([H])(C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C1=C(C([H])=C(OC([H])([H])[H])C([H])=C1[H])S(=O)(=O)C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])C([H])([H])[H])S(=O)(=O)C([H])([H])[H]
[H]O[C@](C1=C([H])C([H])=C([H])C([H])=C1F)(C1=C(C([H])=C([H])C(Cl)=C1[H])S(=O)(=O)C1=C([H])C([H])=C(C([H])=C1[H])[C@@]([H])(N([H])S(=O)(=O)C([H])([H])[H])C([H])([H])[H])C([H])([H])[H]
[H]N([C@]([H])(C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)C1=C(C([H])=C(Cl)C([H])=C1[H])S(=O)(=O)C1=C([H])C([H])=C([H])C([H])=C1OC(F)(F)F)C([H])([H])[H])S(=O)(=O)C([H])([H])[H]
[H]N([C@]([H])(C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)C1=C(C([H])=C(OC2([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])=C1[H])S(=O)(=O)C1=C([H])C([H])=C(Cl)C([H])=C1[H])C([H])([H])[H])S(=O)(=O)C([H])([H])[H]
[H]N([C@]([H])(C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)C1=C(C([H])=C(OC([H])([H])[H])C([H])=C1[H])S(=O)(=O)C1=C([H])C([H])=C(Cl)C([H])=C1[H])C([H])([H])[H])S(=O)(=O)C([H])([H])[H]
[H]N([C@]([H])(C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)C1=C(C([H])=C(Cl)C([H])=C1[H])S(=O)(=O)C1=C([H])C([H])=C([H])C([H])=C1Cl)C([H])([H])[H])S(=O)(=O)C([H])([H])[H]
[H]N([C@]([H])(C1=C([H])C([H])=C(C([H])=C1[H])[C@]([H])(C1=C(C([H])=C(Cl)C([H])=C1[H])S(=O)(=O)C1=C([H])C([H])=C(Cl)C([H])=C1[H])C([H])([H])C([H])([H])[H])C([H])([H])[H])S(=O)(=O)C([H])([H])[H]
[H]N([C@]([H])(C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C1=C(C([H])=C(C([H])=C1[H])C(F)(F)F)S(=O)(=O)C1=C([H])C([H])=C([H])C(F)=C1[H])C([H])([H])[H])S(=O)(=O)C([H])([H])[H]
[H]N([C@]([H])(C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C1=C(C([H])=C(OC(F)(F)F)C([H])=C1[H])S(=O)(=O)C1=C([H])C([H])=C([H])C(=C1[H])C(F)(F)F)C([H])([H])[H])S(=O)(=O)C([H])([H])[H]
[H]N([C@]([H])(C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)C1=C(C([H])=C([H])C([H])=C1[H])S(=O)(=O)C1=C([H])C([H])=C([H])C([H])=C1F)C([H])([H])[H])S(=O)(=O)C([H])([H])[H]
[H]N([C@]([H])(C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)C1=C(C([H])=C(Cl)C([H])=C1[H])C(=O)C1=C([H])C([H])=C(Cl)C([H])=C1[H])C([H])([H])[H])S(=O)(=O)C([H])([H])[H]
[H]OC1=C([H])C(=C(C([H])=C1[H])S(=O)(=O)C1=C([H])C([H])=C(C([H])=C1[H])[C@@]([H])(N([H])S(=O)(=O)C([H])([H])[H])C([H])([H])[H])S(=O)(=O)C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]N([C@]([H])(C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)C1=C(C([H])=C(C([H])=C1[H])C(F)(F)F)S(=O)(=O)C1=C([H])C([H])=C([H])C([H])=C1F)C([H])([H])[H])S(=O)(=O)C([H])([H])[H]
[H]N([C@]([H])(C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C1=C(C([H])=C(OC(F)(F)F)C([H])=C1[H])S(=O)(=O)C1=C([H])C([H])=C([H])C([H])=C1F)C([H])([H])[H])S(=O)(=O)C([H])([H])[H]
[H]O[C@](C1=C([H])C([H])=C(Cl)C([H])=C1[H])(C1=C(C([H])=C([H])C(Cl)=C1[H])S(=O)(=O)C1=C([H])C([H])=C(C([H])=C1[H])[C@@]([H])(N([H])S(=O)(=O)C([H])([H])[H])C([H])([H])[H])C([H])([H])[H]
[H]N([C@]([H])(C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)C1=C(C([H])=C(Cl)C([H])=C1[H])S(=O)(=O)C1=C([H])C([H])=C([H])C(Cl)=C1[H])C([H])([H])[H])S(=O)(=O)C([H])([H])[H]
[H]N([C@]([H])(C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)C1=C(OC2=C([H])C([H])=C(Cl)C([H])=C2[H])C([H])=C(Cl)C([H])=C1[H])C([H])([H])[H])S(=O)(=O)C([H])([H])[H]
[H]N(C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)C1=C(C([H])=C(OC([H])([H])[H])C([H])=C1[H])S(=O)(=O)C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])S(=O)(=O)C([H])([H])[H]
[H]N([C@]([H])(C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)C1=C(C([H])=C(C([H])=C1[H])C(F)(F)F)S(=O)(=O)C1=C([H])C([H])=C(Cl)C([H])=C1[H])C([H])([H])[H])S(=O)(=O)C([H])([H])[H]
[H]N([C@]([H])(C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C1=C(C([H])=C(C([H])=C1[H])C(F)(F)F)S(=O)(=O)C1=C([H])C([H])=C([H])C([H])=C1F)C([H])([H])[H])S(=O)(=O)C([H])([H])[H]
[H]C([H])=C(C1=C([H])C([H])=C([H])C([H])=C1F)C1=C(C([H])=C([H])C(Cl)=C1[H])S(=O)(=O)C1=C([H])C([H])=C(C([H])=C1[H])[C@@]([H])(N([H])S(=O)(=O)C([H])([H])[H])C([H])([H])[H]
[H]N([C@]([H])(C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)C1=C(C([H])=C(C([H])=C1[H])C([H])([H])[H])S(=O)(=O)C1=C([H])C([H])=C([H])C([H])=C1F)C([H])([H])[H])S(=O)(=O)C([H])([H])[H]
[H]N([C@]([H])(C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C1=C(C([H])=C(C([H])=C1[H])C(F)(F)F)S(=O)(=O)C1=C(F)C([H])=C([H])C([H])=C1F)C([H])([H])[H])S(=O)(=O)C([H])([H])[H]
[H]N(C1=C([H])C([H])=C(Cl)C([H])=C1[H])C1=C(C([H])=C([H])C(Cl)=C1[H])S(=O)(=O)C1=C([H])C([H])=C(C([H])=C1[H])[C@@]([H])(N([H])S(=O)(=O)C([H])([H])[H])C([H])([H])[H]
[H]N(C(C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)C1=C(C([H])=C(OC([H])([H])[H])C([H])=C1[H])S(=O)(=O)C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])(C([H])([H])[H])C([H])([H])[H])S(=O)(=O)C([H])([H])[H]
[H]N([C@]([H])(C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C1=C(C([H])=C(OC(F)(F)F)C([H])=C1[H])S(=O)(=O)C1=C([H])C([H])=C([H])C([H])=C1OC(F)(F)F)C([H])([H])[H])S(=O)(=O)C([H])([H])[H]
[H]C1=C([H])C(=C([H])C([H])=C1Cl)C1=C(N=C2N(C(=O)C(C(=O)C([H])([H])[H])=C(N(C([H])([H])[H])C([H])([H])[H])C2=C1[H])C([H])([H])[H])C1=C([H])C([H])=C(Cl)C([H])=C1Cl
[H]N(C(=O)C([H])([H])OC([H])([H])[H])C1=C(C(=O)C([H])([H])[H])C(=O)N(C2=C1C([H])=C(C1=C([H])C([H])=C(Cl)C([H])=C1[H])C(=N2)C1=C([H])C([H])=C(Cl)C([H])=C1Cl)C([H])([H])[H]
[H]N(C(=O)C([H])([H])[H])C1=C(C(=O)C([H])([H])[H])C(=O)N(C2=C1C([H])=C(C1=C([H])C([H])=C(Cl)C([H])=C1[H])C(=N2)C1=C([H])C([H])=C(Cl)C([H])=C1Cl)C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N([H])C1=C(C(=O)C([H])([H])[H])C(=O)N(C2=C1C([H])=C(C1=C([H])C([H])=C(Cl)C([H])=C1[H])C(=N2)C1=C([H])C([H])=C(Cl)C([H])=C1Cl)C([H])([H])[H]
[H]N(C(=O)C([H])([H])[H])C1=C(C(=O)C([H])([H])[H])C(=O)N(C2=C1C([H])=C(C1=C([H])C([H])=C(Cl)C([H])=C1[H])C(=N2)C1=C([H])C([H])=C(Cl)C([H])=C1Cl)C([H])([H])C([H])([H])OC([H])([H])[H]
[H]N(C(=O)C([H])([H])[H])C1=C([H])C(=O)N(C2=NC(C3=C([H])C([H])=C(Cl)C([H])=C3Cl)=C(C([H])=C12)C1=C([H])C([H])=C(Cl)C([H])=C1[H])C([H])([H])[H]
[H]N(C(=O)C([H])([H])[H])C1=C(C(=O)C([H])([H])[H])C(=O)N(C2=C1C([H])=C(C1=C([H])C([H])=C(Cl)C([H])=C1[H])C(=N2)C1=C([H])C([H])=C(Cl)C([H])=C1Cl)C([H])([H])[C@@]1([H])OC([H])([H])C([H])([H])C1([H])[H]
[H]N(C(=O)C([H])([H])[H])C1=C(C#N)C(=O)N(C2=NC(C3=C([H])C([H])=C(Cl)C([H])=C3Cl)=C(C([H])=C12)C1=C([H])C([H])=C(Cl)C([H])=C1[H])C([H])([H])[H]
[H]ON(C(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C(\[H])=C(\[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])O[H]
[H]ON(C(=O)C([H])([H])C([H])([H])C([H])([H])C(\[H])=C(\[H])C([H])([H])C(\[H])=C(\[H])C([H])([H])C(\[H])=C(\[H])C([H])([H])C(\[H])=C(\[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])O[H]
[H]OC([H])([H])[C@]([H])(N([H])C(=O)C([H])([H])C([H])([H])C([H])([H])C(\[H])=C(\[H])C([H])([H])C(\[H])=C(\[H])C([H])([H])C(\[H])=C(\[H])C([H])([H])C(\[H])=C(\[H])C([H])([H])C([H])([H])OC(=O)C1=C([H])C(I)=C([H])C([H])=C1N=[N+]=[N-])C([H])([H])[H]
[H]N(C(=O)C(OC1=C([H])C([H])=C(Cl)C([H])=C1[H])(C([H])([H])[H])C([H])([H])[H])[C@@]([H])(C([H])([H])[H])[C@]([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]N(C(=O)C(OC1=C([H])C([H])=C([H])C(Cl)=C1[H])(C([H])([H])[H])C([H])([H])[H])[C@@]([H])(C([H])([H])[H])[C@]([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
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[H]N(C(=O)C(OC1=C([H])C(F)=C([H])C(F)=C1[H])(C([H])([H])[H])C([H])([H])[H])[C@@]([H])(C([H])([H])[H])[C@]([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]N(C(=O)C(OC1=C([H])C([H])=C(Cl)C([H])=C1[H])(C([H])([H])[H])C([H])([H])[H])[C@@]([H])(C([H])([H])[H])[C@]([H])(C1=C([H])C([H])=C(Cl)C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]N(C(=O)C(OC1=C([H])C([H])=C(C([H])=N1)C(F)(F)F)(C([H])([H])[H])C([H])([H])[H])[C@@]([H])(C([H])([H])[H])[C@]([H])(C1=C([H])C([H])=C([H])C(C#N)=C1[H])C([H])([H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]N(C(=O)C(OC1=C([H])C([H])=C([H])C([H])=N1)(C([H])([H])[H])C([H])([H])[H])[C@@]([H])(C([H])([H])[H])[C@]([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]N(C(=O)C(OC1=C([H])C([H])=C(C([H])=N1)C(F)(F)F)(C([H])([H])[H])C([H])([H])[H])[C@@]([H])(C([H])([H])[H])[C@]([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]N(C(=O)C(OC1=C([H])C([H])=C([H])C(F)=C1[H])(C([H])([H])[H])C([H])([H])[H])[C@@]([H])(C([H])([H])[H])[C@]([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]N(C(=O)C(OC1=C([H])C([H])=C(Cl)C([H])=N1)(C([H])([H])[H])C([H])([H])[H])[C@@]([H])(C([H])([H])[H])[C@]([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]OC([H])([H])C([H])([H])ON([H])C(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C(\[H])=C(\[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]OC([H])([H])C([H])([H])N([H])OC(=O)C([H])([H])C([H])([H])C([H])([H])C(\[H])=C(\[H])C([H])([H])C(\[H])=C(\[H])C([H])([H])C(\[H])=C(\[H])C([H])([H])C(\[H])=C(\[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]OC([H])([H])C([H])([H])N([H])OC(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C(\[H])=C(\[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]OC([H])([H])C([H])([H])ON([H])C(=O)C([H])([H])C([H])([H])C([H])([H])C(\[H])=C(\[H])C([H])([H])C(\[H])=C(\[H])C([H])([H])C(\[H])=C(\[H])C([H])([H])C(\[H])=C(\[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]C1=C(C([H])=C(N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])C(=O)C1=C2C([H])=C([H])C([H])=C([H])C2=C([H])C([H])=C1[H]
[H]C1=C(C([H])=C(N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C1=C([H])C([H])=C(F)C([H])=C1[H])C(=O)C1=C2C([H])=C([H])C([H])=C([H])C2=C([H])C([H])=C1[H]
[H]C1=C(C([H])=C(N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C(=O)C1=C2C([H])=C([H])C([H])=C([H])C2=C([H])C([H])=C1[H]
[H]C1=C(C([H])=C(N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C1=C([H])C([H])=C([H])C(F)=C1[H])C(=O)C1=C2C([H])=C([H])C([H])=C([H])C2=C([H])C([H])=C1[H]
[H]C1=C(C([H])=C(N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1F)C(=O)C1=C2C([H])=C([H])C([H])=C([H])C2=C([H])C([H])=C1[H]
[H]C1=C(C([H])=C(N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1C([H])([H])C([H])([H])[H])C(=O)C1=C2C([H])=C([H])C([H])=C([H])C2=C([H])C([H])=C1[H]
[H]C1=C(C([H])=C(N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1Cl)C(=O)C1=C2C([H])=C([H])C([H])=C([H])C2=C([H])C([H])=C1[H]
[H]C1=C(C([H])=C(N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1C([H])([H])[H])C(=O)C1=C2C([H])=C([H])C([H])=C([H])C2=C([H])C([H])=C1[H]
[H]C1=C(C([H])=C(N1C([H])([H])C([H])([H])C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C(=O)C1=C2C([H])=C([H])C([H])=C([H])C2=C([H])C([H])=C1[H]
[H]C1=C(C([H])=C(N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C1=C([H])C([H])=C([H])C(OC([H])([H])[H])=C1[H])C(=O)C1=C2C([H])=C([H])C([H])=C([H])C2=C([H])C([H])=C1[H]
[H]C1=C(C([H])=C(N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C(F)(F)F)C(=O)C1=C2C([H])=C([H])C([H])=C([H])C2=C([H])C([H])=C1[H]
[H]C1=C(C([H])=C(N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C(=O)C1=C2C([H])=C([H])C([H])=C([H])C2=C([H])C([H])=C1[H]
[H]C1=C(C([H])=C(N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C1=C([H])C([H])=C([H])C(=C1[H])C(F)(F)F)C(=O)C1=C2C([H])=C([H])C([H])=C([H])C2=C([H])C([H])=C1[H]
[H]C1=C(C([H])=C(N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C1=C([H])C([H])=C([H])C(Cl)=C1[H])C(=O)C1=C2C([H])=C([H])C([H])=C([H])C2=C([H])C([H])=C1[H]
[H]C1=C(C([H])=C(N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C1=C([H])C([H])=C([H])C(=C1[H])C([H])([H])[H])C(=O)C1=C2C([H])=C([H])C([H])=C([H])C2=C([H])C([H])=C1[H]
[H]C1=C(C([H])=C(N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1C(F)(F)F)C(=O)C1=C2C([H])=C([H])C([H])=C([H])C2=C([H])C([H])=C1[H]
[H]C1=C(C([H])=C(N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H])C(=O)C1=C2C([H])=C([H])C([H])=C([H])C2=C([H])C([H])=C1[H]
[H]C1=C(C([H])=C(N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C(=O)C1=C2C([H])=C([H])C([H])=C([H])C2=C([H])C([H])=C1[H]
[H]C1=C(C([H])=C(N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C1=C([H])C([H])=C(Cl)C([H])=C1[H])C(=O)C1=C2C([H])=C([H])C([H])=C([H])C2=C([H])C([H])=C1[H]
[H]C1=C(C([H])=C(N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1OC([H])([H])[H])C(=O)C1=C2C([H])=C([H])C([H])=C([H])C2=C([H])C([H])=C1[H]
[H]C1=C(C([H])=C(N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C(=O)C1=C2C([H])=C([H])C([H])=C([H])C2=C([H])C([H])=C1[H]
[H]C1=C(C([H])=C(N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C1=C([H])N=C([H])C([H])=C1[H])C(=O)C1=C2C([H])=C([H])C([H])=C([H])C2=C([H])C([H])=C1[H]
[H]C1=C(C([H])=C(N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C1=C2C([H])=C([H])C([H])=C([H])C2=C([H])C([H])=C1[H])C(=O)C1=C2C([H])=C([H])C([H])=C([H])C2=C([H])C([H])=C1[H]
[H]C1=C(C([H])=C(N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C(=O)C1=C2C([H])=C([H])C([H])=C([H])C2=C([H])C([H])=C1[H]
[H]C1=C(C([H])=C(N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C1=C([H])C([H])=C([H])C(=C1[H])[N+]([O-])=O)C(=O)C1=C2C([H])=C([H])C([H])=C([H])C2=C([H])C([H])=C1[H]
[H]C1=C(C([H])=C(N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])[H])C(=O)C1=C2C([H])=C([H])C([H])=C([H])C2=C([H])C([H])=C1[H]
[H]N([C@@]([H])(C([H])([H])[H])[C@]([H])(C1=C([H])C([H])=C([H])C(C#N)=C1[H])C([H])([H])C1=C([H])C([H])=C(Cl)C([H])=C1[H])S(=O)(=O)C1=C([H])C([H])=C([H])C(Cl)=C1Cl
[H]N([C@@]([H])(C([H])([H])[H])[C@]([H])(C1=C([H])C([H])=C([H])C(C#N)=C1[H])C([H])([H])C1=C([H])C([H])=C(Cl)C([H])=C1[H])S(=O)(=O)C1=C([H])C([H])=C([H])C(=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N([C@@]([H])(C([H])([H])[H])[C@]([H])(C1=C([H])C([H])=C([H])C(C#N)=C1[H])C([H])([H])C1=C([H])C([H])=C(Cl)C([H])=C1[H])S(=O)(=O)C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]N([C@@]([H])(C([H])([H])[H])[C@]([H])(C1=C([H])C([H])=C([H])C(C#N)=C1[H])C([H])([H])C1=C([H])C([H])=C(Cl)C([H])=C1[H])S(=O)(=O)C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N([C@@]([H])(C([H])([H])[H])[C@]([H])(C1=C([H])C([H])=C([H])C(C#N)=C1[H])C([H])([H])C1=C([H])C([H])=C(Cl)C([H])=C1[H])S(=O)(=O)C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C1=C([H])N(C([H])=N1)C1=NC(C2=C([H])C([H])=C(Cl)C([H])=C2Cl)=C(C([H])=C1C#N)C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]C1=C([H])C(=C([H])C([H])=C1Cl)C1=C(N=C(O[C@]2([H])C([H])([H])OC([H])([H])C2([H])[H])C(C#N)=C1[H])C1=C([H])C([H])=C(Cl)C([H])=C1Cl
[H]N([H])C(=O)C1=C([H])C(C2=C([H])C([H])=C(Cl)C([H])=C2[H])=C(N=C1OC1=C([H])C([H])=C(F)C(F)=C1[H])C1=C([H])C([H])=C(Cl)C([H])=C1Cl
[H]C1=C([H])C([H])=C(C(Cl)=C1[H])C1=C(C([H])=C(C#N)C(=N1)N1C(=O)C(=O)N(C([H])([H])C1([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]C1=C([H])C([H])=C(C(Cl)=C1[H])C1=C(C([H])=C(C#N)C(=N1)C#CC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]C1=C([H])C(=C([H])C([H])=C1Cl)C1=C(N=C(OC([H])(C([H])([H])[H])C([H])([H])[H])C(C#N)=C1[H])C1=C([H])C([H])=C(Cl)C([H])=C1Cl
[H]N(C(=O)C1([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C([H])([H])OC1=NC(C2=C([H])C([H])=C(Cl)C([H])=C2Cl)=C(C([H])=C1C#N)C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]C1=C([H])C([H])=C(C(Cl)=C1[H])C1=C(C([H])=C(C#N)C(=N1)N1C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])S(=O)(=O)C1=C([H])C(F)=C([H])C(F)=C1[H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]OC([H])([H])C([H])(OC(=O)C([H])([H])C([H])([H])C([H])([H])C(\[H])=C(\[H])C([H])([H])C(\[H])=C(\[H])C([H])([H])C(\[H])=C(\[H])C([H])([H])C(\[H])=C(\[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])O[H]
[H]OC1=C([H])C([H])=C([H])C(OC([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C(=O)N([H])C([H])([H])C2([H])C([H])([H])C2([H])[H])=C1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]OC1=C([H])C(OC([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C(=O)N([H])C([H])([H])C2([H])C([H])([H])C2([H])[H])=C([H])C([H])=C1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]OC1=C([H])C([H])=C([H])C(OC([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C(=O)N([H])C2([H])C([H])([H])C2([H])[H])=C1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]OC1=C([H])C([H])=C([H])C(OC([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C(=O)N([H])C([H])([H])C([H])([H])O[H])=C1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]OC1=C([H])C(=C([H])C([H])=C1OC([H])([H])[H])C([H])([H])N([H])C(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])OC1=C(C(O[H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]OC1=C([H])C([H])=C(C([H])=C1O[H])C([H])([H])C([H])([H])N([H])C(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])OC1=C(C(O[H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]OC1=C([H])C(OC([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C(=O)N([H])C([H])([H])C2([H])C([H])([H])C2([H])[H])=C([H])C(=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]OC1=C([H])C(OC([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C(=O)N([H])C([H])([H])C2=C([H])C([H])=C(OC([H])([H])[H])C(O[H])=C2[H])=C([H])C(=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]N([C@@]([H])(C([H])([H])[H])[C@]([H])(C1=C([H])C([H])=C([H])C(C#N)=C1[H])C([H])([H])C1=C([H])C([H])=C(Cl)C([H])=C1[H])S(=O)(=O)C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N([C@@]([H])(C([H])([H])[H])[C@]([H])(C1=C([H])C([H])=C([H])C(C#N)=C1[H])C([H])([H])C1=C([H])C([H])=C(Cl)C([H])=C1[H])S(=O)(=O)C1=C([H])C([H])=C(Cl)C([H])=C1Cl
[H]C1=C([H])C(C#N)=C([H])C(=C1[H])[C@]([H])(C([H])([H])C1=C([H])C([H])=C(Cl)C([H])=C1[H])[C@@]([H])(N(C([H])([H])[H])S(=O)(=O)C1=C([H])C(Cl)=C([H])C(Cl)=C1[H])C([H])([H])[H]
[H]N([C@@]([H])(C([H])([H])[H])[C@]([H])(C1=C([H])C([H])=C([H])C(C#N)=C1[H])C([H])([H])C1=C([H])C([H])=C(Cl)C([H])=C1[H])S(=O)(=O)C1=C([H])C(Cl)=C(Cl)C([H])=C1Cl
[H]N(C(=O)C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])[C@@]([H])(C([H])([H])[H])[C@]([H])(C1=C([H])C([H])=C([H])C(C#N)=C1[H])C([H])([H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]N(C(=O)C1=C([H])C(Cl)=C([H])C(Cl)=C1[H])[C@@]([H])(C([H])([H])[H])[C@]([H])(C1=C([H])C([H])=C([H])C(C#N)=C1[H])C([H])([H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]N([C@@]([H])(C([H])([H])[H])[C@]([H])(C1=C([H])C([H])=C([H])C(C#N)=C1[H])C([H])([H])C1=C([H])C([H])=C(Cl)C([H])=C1[H])S(=O)(=O)C([H])([H])C1=C(Cl)C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)C(OC1=C([H])N=C([H])C(=C1[H])C(F)(F)F)(C([H])([H])[H])C([H])([H])[H])[C@@]([H])(C([H])([H])[H])[C@]([H])(C1=C([H])C([H])=C([H])C(C#N)=C1[H])C([H])([H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]N([C@@]([H])(C([H])([H])[H])[C@]([H])(C1=C([H])C([H])=C([H])C(C#N)=C1[H])C([H])([H])C1=C([H])C([H])=C(Cl)C([H])=C1[H])S(=O)(=O)C1=C([H])C([H])=C([H])C([H])=C1Cl
[H]N(C(=O)C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])[C@@]([H])(C([H])([H])[H])[C@]([H])(C1=C([H])C([H])=C([H])C(C#N)=C1[H])C([H])([H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]N([C@@]([H])(C([H])([H])[H])[C@]([H])(C1=C([H])C([H])=C([H])C(C#N)=C1[H])C([H])([H])C1=C([H])C([H])=C(Cl)C([H])=C1[H])S(=O)(=O)C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N([C@@]([H])(C([H])([H])[H])[C@]([H])(C1=C([H])C([H])=C([H])C(C#N)=C1[H])C([H])([H])C1=C([H])C([H])=C(Cl)C([H])=C1[H])S(=O)(=O)C1=C([H])C([H])=C2C([H])=C([H])C([H])=C([H])C2=C1[H]
[H]N([C@@]([H])(C([H])([H])[H])[C@]([H])(C1=C([H])C([H])=C([H])C(C#N)=C1[H])C([H])([H])C1=C([H])C([H])=C(Cl)C([H])=C1[H])S(=O)(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]N(C(=O)C1=C(Cl)C([H])=C([H])C([H])=C1Cl)[C@@]([H])(C([H])([H])[H])[C@]([H])(C1=C([H])C([H])=C([H])C(C#N)=C1[H])C([H])([H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]N([C@@]([H])(C([H])([H])[H])[C@]([H])(C1=C([H])C([H])=C([H])C(C#N)=C1[H])C([H])([H])C1=C([H])C([H])=C(Cl)C([H])=C1[H])S(=O)(=O)C1=C([H])C(Cl)=C([H])C(Cl)=C1[H]
[H]C1=C([H])C(C#N)=C([H])C(=C1[H])[C@]([H])(C([H])([H])C1=C([H])C([H])=C(Cl)C([H])=C1[H])[C@@]([H])(N(C([H])([H])[H])S(=O)(=O)C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C([H])C([H])=C1[H])[C@@]([H])(C([H])([H])[H])[C@]([H])(C1=C([H])C([H])=C([H])C(C#N)=C1[H])C([H])([H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]N([C@@]([H])(C([H])([H])[H])[C@]([H])(C1=C([H])C([H])=C([H])C(C#N)=C1[H])C([H])([H])C1=C([H])C([H])=C(Cl)C([H])=C1[H])S(=O)(=O)C1=C([H])C(F)=C([H])C(F)=C1[H]
[H]N([C@@]([H])(C([H])([H])[H])[C@]([H])(C1=C([H])C([H])=C([H])C(C#N)=C1[H])C([H])([H])C1=C([H])C([H])=C(Cl)C([H])=C1[H])S(=O)(=O)C([H])([H])[H]
[H]N(C1=NC([H])=C(C(=O)N([H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C(=N1)C(F)(F)F)C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C1=NC([H])=C(C(=O)N([H])C([H])([H])C2=C([H])C([H])=NC([H])=C2[H])C(=N1)C(F)(F)F)C1=C([H])C([H])=C([H])C(Cl)=C1[H]
[H]N(C1=NC([H])=C(C(=O)N([H])C([H])([H])C2([H])C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])C(=N1)C(F)(F)F)C1=C([H])C(F)=C([H])C(F)=C1[H]
[H]C1=C([H])C([H])=C(C(Cl)=C1[H])C1=C(C([H])=C(C#N)C(OC2=C([H])C([H])=C(F)C(F)=C2[H])=N1)C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]N(C1=NC(C2=C([H])C([H])=C(Cl)C([H])=C2Cl)=C(C([H])=C1C#N)C1=C([H])C([H])=C(Cl)C([H])=C1[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])C(=C([H])C([H])=C1Cl)C1=C(N=C(OC([H])([H])[C@]2([H])C([H])([H])OC([H])([H])C2([H])[H])C(C#N)=C1[H])C1=C([H])C([H])=C(Cl)C([H])=C1Cl
[H]C1=C([H])C(F)=C([H])C(OC2=NC(C3=C([H])C([H])=C(Cl)C([H])=C3Cl)=C(C([H])=C2C#N)C2=C([H])C([H])=C(Cl)C([H])=C2[H])=C1[H]
[H]C1=C([H])C2=C(C([H])=C1[H])N(N=N2)C1=NC(C2=C([H])C([H])=C(Cl)C([H])=C2Cl)=C(C([H])=C1C#N)C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]N(N(C(=O)C1=C([H])C(C2=C([H])C([H])=C(Cl)C([H])=C2[H])=C(N=C1OC1=C([H])C([H])=C(F)C(F)=C1[H])C1=C([H])C([H])=C(Cl)C([H])=C1Cl)C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])C(=C([H])C([H])=C1Cl)C1=C(N=C(OC2=C([H])C([H])=C(F)C(F)=C2[H])C(C#N)=C1[H])C1=C([H])C([H])=C(Cl)C([H])=C1Cl
[H]C1=NC([H])=C(C([H])=N1)C1=NC(C2=C([H])C([H])=C([H])C([H])=C2Cl)=C(C([H])=C1C#N)C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]C1=C([H])C(=C([H])C([H])=C1Cl)C1=C(N=C(N2C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C(C#N)=C1[H])C1=C([H])C([H])=C(Cl)C([H])=C1Cl
[H]C1=C([H])C(=C([H])C([H])=C1Cl)C1=C(C2=C(N1C1=C([H])C([H])=C(Cl)C([H])=C1Cl)C([H])([H])C([H])([H])N(N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C2=O)C([H])([H])[H]
[H]C1=C([H])C(OC2=NC(C3=C([H])C([H])=C(Cl)C([H])=C3Cl)=C(C([H])=C2C#N)C2=C([H])C([H])=C(Cl)C([H])=C2[H])=C([H])C([H])=C1F
[H]N(C(=O)C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C1=NC(C2=C([H])C([H])=C(Cl)C([H])=C2Cl)=C(C([H])=C1C#N)C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]C1=C([H])C(=C([H])C([H])=C1Cl)C1=C(N=C(OC2=C([H])C(F)=C([H])C(F)=C2[H])C(C#N)=C1[H])C1=C([H])C([H])=C(Cl)C([H])=C1Cl
[H]C1=C([H])C([H])=C(C([H])=N1)C1=NC(C2=C([H])C([H])=C([H])C([H])=C2Cl)=C(C([H])=C1C#N)C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]C1=C([H])C(=C([H])C([H])=C1Cl)C1=C(N=C(OC2=C([H])C(Cl)=C([H])C(Cl)=C2[H])C(C#N)=C1[H])C1=C([H])C([H])=C(Cl)C([H])=C1Cl
[H]C1=C([H])C(Cl)=C([H])C(OC2=NC(C3=C([H])C([H])=C(Cl)C([H])=C3Cl)=C(C([H])=C2C#N)C2=C([H])C([H])=C(Cl)C([H])=C2[H])=C1[H]
[H]C1=C([H])C(=C([H])C([H])=C1Cl)C1=C(N=C(OC2=C([H])C([H])=C(OC([H])([H])[H])C([H])=C2[H])C(C#N)=C1[H])C1=C([H])C([H])=C(Cl)C([H])=C1Cl
[H]N([H])C(C#CC1=NC(C2=C([H])C([H])=C([H])C([H])=C2Cl)=C(C([H])=C1C#N)C1=C([H])C([H])=C(Cl)C([H])=C1[H])(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H]
[H]C1=NN(C([H])=C1C1=NC(C2=C([H])C([H])=C([H])C([H])=C2Cl)=C(C([H])=C1C#N)C1=C([H])C([H])=C(Cl)C([H])=C1[H])C([H])([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C(F)C(F)=C1[H])C1=NC(C2=C([H])C([H])=C(Cl)C([H])=C2Cl)=C(C([H])=C1C#N)C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]N(C(=O)C1=C([H])C(C2=C([H])C([H])=C(Cl)C([H])=C2[H])=C(N=C1OC1=C([H])C([H])=C(F)C(F)=C1[H])C1=C([H])C([H])=C(Cl)C([H])=C1Cl)C([H])(C([H])([H])[H])C([H])([H])[H]
[H]OC1=C(C(OC([H])([H])[H])=C([H])C(=C1[H])C(=O)OC([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C1=C([H])C(=C([H])C(=C1[H])C([H])([H])[H])C([H])([H])[H]
[H]OC1=C(C(OC([H])([H])[H])=C([H])C(=C1[H])C(=O)OC([H])([H])[H])C1=C([H])C(=C([H])C(=C1[H])C([H])([H])[H])C([H])([H])[H]
[H]OC1=C([H])C(=C([H])C(O[H])=C1C1=C([H])C([H])=C([H])C([H])=C1[H])C(=O)OC([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]N([C@@]([H])(C([H])([H])[H])[C@]([H])(C1=C([H])C([H])=C([H])C(C#N)=C1[H])C([H])([H])C1=C([H])C([H])=C(Cl)C([H])=C1[H])S(=O)(=O)C1=C([H])C(=C([H])C(=C1[H])C(F)(F)F)C(F)(F)F
[H]N([C@@]([H])(C([H])([H])[H])[C@]([H])(C1=C([H])C([H])=C([H])C(C#N)=C1[H])C([H])([H])C1=C([H])C([H])=C(Cl)C([H])=C1[H])S(=O)(=O)C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]N([C@@]([H])(C([H])([H])[H])[C@]([H])(C1=C([H])C([H])=C([H])C(C#N)=C1[H])C([H])([H])C1=C([H])C([H])=C(Cl)C([H])=C1[H])S(=O)(=O)C1=C([H])C([H])=C([H])C(Cl)=C1[H]
[H]N([C@@]([H])(C([H])([H])[H])[C@]([H])(C1=C([H])C([H])=C([H])C(C#N)=C1[H])C([H])([H])C1=C([H])C([H])=C(Cl)C([H])=C1[H])S(=O)(=O)C([H])([H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]N([C@@]([H])(C([H])([H])[H])[C@]([H])(C1=C([H])C([H])=C([H])C(C#N)=C1[H])C([H])([H])C1=C([H])C([H])=C(Cl)C([H])=C1[H])S(=O)(=O)C(\[H])=C(/[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C1=C([H])C(=C([H])C([H])=C1Cl)C1=C(C2=C(N1C1=C([H])C([H])=C(Cl)C([H])=C1Cl)C([H])([H])C([H])([H])N(C2=O)C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])[H]
[H]C1=C([H])C([H])=C(N2C(=C(C3=C2C([H])([H])C([H])([H])N(N2C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C3=O)C([H])([H])[H])C2=C([H])C([H])=C(Cl)C([H])=C2[H])C(Cl)=C1[H]
[H]O[C@@]1([H])C([H])([H])C([H])([H])C([H])([H])[C@]1([H])N([H])C(=O)C1=C([H])N(C(=N1)C1=C([H])C([H])=C([H])C([H])=C1Cl)C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]O[C@@]1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])N([H])C(=O)C1=C([H])N(C(=N1)C1=C([H])C([H])=C(Cl)C([H])=C1Cl)C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]O[C@@]1([H])C([H])([H])C2=C(C([H])=C([H])C([H])=C2[H])[C@@]1([H])N([H])C(=O)C1=C([H])N(C(=N1)C1=C([H])C([H])=C([H])C([H])=C1Cl)C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]O[C@@]1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@]1([H])N([H])C(=O)C1=C([H])N(C(=N1)C1=C([H])C([H])=C([H])C([H])=C1Cl)C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]O[C@@]1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@]1([H])N([H])C(=O)C1=C(N(C(=N1)C1=C([H])C([H])=C([H])C([H])=C1Cl)C1=C([H])C([H])=C(Cl)C([H])=C1[H])C([H])([H])C([H])([H])[H]
[H]C1=C([H])C([H])=C(N2C(=C(C3=C2C([H])([H])C([H])([H])N(N2C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C3=O)C([H])([H])[H])C2=C([H])C([H])=C(OC([H])([H])[H])C([H])=C2[H])C(Cl)=C1[H]
[H]N([C@@]([H])(C([H])([H])[H])[C@]([H])(C1=C([H])C([H])=C([H])C(C#N)=C1[H])C([H])([H])C1=C([H])C([H])=C(Cl)C([H])=C1[H])S(=O)(=O)C([H])([H])C1=C([H])C(Cl)=C([H])C([H])=C1[H]
[H]N([C@@]([H])(C([H])([H])[H])[C@]([H])(C1=C([H])C([H])=C([H])C(C#N)=C1[H])C([H])([H])C1=C([H])C([H])=C(Cl)C([H])=C1[H])S(=O)(=O)C1=C(Cl)C([H])=C([H])C([H])=C1Cl
[H]N([C@@]([H])(C([H])([H])[H])[C@]([H])(C1=C([H])C([H])=C([H])C(C#N)=C1[H])C([H])([H])C1=C([H])C([H])=C(Cl)C([H])=C1[H])S(=O)(=O)C1=C([H])C(Cl)=C([H])C([H])=C1Cl
[H]C1=C([H])C([H])=C2C(C([H])=C([H])C([H])=C2C(=O)C2=C([H])C([H])=C(OC([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C3=C([H])C([H])=C([H])C([H])=C23)=C1[H]
[H]N(C1=C([H])C([H])=C(C(=O)C2=C([H])C([H])=C([H])C3=C([H])C([H])=C([H])C([H])=C23)C2=C([H])C([H])=C([H])C([H])=C12)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]C1=C([H])C([H])=C2C(C([H])=C([H])C([H])=C2C(=O)C2=C([H])C([H])=C(OC([H])([H])C([H])([H])C([H])([H])[H])C3=C([H])C([H])=C([H])C([H])=C23)=C1[H]
[H]C1=C([H])C([H])=C2C(C([H])=C([H])C([H])=C2C(=O)C2=C([H])C([H])=C(OC([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C3=C([H])C([H])=C([H])C([H])=C23)=C1[H]
[H]N(C1=NC(C2=C([H])C([H])=C(Cl)C([H])=C2Cl)=C(C([H])=C1C#N)C1=C([H])C([H])=C(Cl)C([H])=C1[H])C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]OC(C#CC1=NC(C2=C([H])C([H])=C([H])C([H])=C2Cl)=C(C([H])=C1C#N)C1=C([H])C([H])=C(Cl)C([H])=C1[H])(C([H])([H])[H])C([H])([H])[H]
[H]N(N(C([H])([H])[H])C([H])([H])[H])C(=O)C1=C([H])C(C2=C([H])C([H])=C(Cl)C([H])=C2[H])=C(N=C1OC1=C([H])C([H])=C(F)C(F)=C1[H])C1=C([H])C([H])=C(Cl)C([H])=C1Cl
[H]C1=C([H])C([H])=C(C(Cl)=C1[H])C1=C(C([H])=C(C#N)C(=N1)N1C([H])([H])C([H])([H])N(C(=O)C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]C1=C([H])C([H])=C2C(C([H])=C([H])C([H])=C2C(=O)C2=C([H])C([H])=C(OC([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C3=C([H])C([H])=C([H])C([H])=C23)=C1[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])OC1=C([H])C([H])=C(C(=O)C2=C([H])C([H])=C([H])C3=C([H])C([H])=C([H])C([H])=C23)C2=C([H])C([H])=C([H])C([H])=C12
[H]N(C(=O)C1=C([H])N(C(=N1)C1=C([H])C([H])=C(Cl)C([H])=C1Cl)C1=C([H])C([H])=C(Cl)C([H])=C1[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(C(=O)C1=C([H])N(C(=N1)C1=C([H])C([H])=C([H])C([H])=C1C([H])([H])[H])C1=C([H])C([H])=C(Cl)C([H])=C1[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]C1=C([H])C(OC2=NC(C3=C([H])C([H])=C(Cl)C([H])=C3Cl)=C(C([H])=C2C#N)C2=C([H])C([H])=C(Cl)C([H])=C2[H])=C([H])C([H])=C1Cl
[H]C1=C([H])C(SC2=NC(C3=C([H])C([H])=C(Cl)C([H])=C3Cl)=C(C([H])=C2C#N)C2=C([H])C([H])=C(Cl)C([H])=C2[H])=C([H])C([H])=C1F
[H]C1=C([H])C([H])=C(C(Cl)=C1[H])C1=C(C([H])=C(C#N)C(=N1)N1C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]OC(=O)C1=C([H])C([H])=C([H])C(=C1[H])C1=C(O[H])C([H])=C(C([H])=C1[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]OC1=C(C([H])=C([H])C(=C1[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C1=C([H])C([H])=C(N([H])[H])C([H])=C1[H]
[H]OC1=C(C([H])=C([H])C(=C1[H])C1(C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C1=C([H])C(=C([H])C(=C1[H])C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])C(=C([H])C(OC([H])([H])[H])=C1C1=C([H])C(=C([H])C(=C1[H])C([H])([H])[H])C([H])([H])[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]C1=C([H])C(=C([H])C(=C1C1=C([H])C(=C([H])C(=C1[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])OC(=O)C([H])([H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]OC1=C(C([H])=C([H])C(=C1[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C1=C(N([H])[H])C([H])=C([H])C([H])=C1[H]
[H]OC1=C(C([H])=C([H])C(=C1[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])O[H])C1=C([H])C(=C([H])C(=C1[H])C([H])([H])[H])C([H])([H])[H]
[H]OC1=C(C([H])=C([H])C(=C1[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])O[H])C1=C([H])C(=C([H])C(=C1[H])C([H])([H])[H])C([H])([H])[H]
[H]N([H])C(=O)C1=C(C([H])=C([H])C(=C1[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C1=C([H])C(=C([H])C(=C1[H])C([H])([H])[H])C([H])([H])[H]
[H]OC([H])([H])C1=C(C([H])=C([H])C(=C1[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C1=C([H])C(=C([H])C(=C1[H])C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])C(C(=O)N2C3=C([H])C([H])=C(OC([H])([H])[H])C([H])=C3C(=C2C([H])([H])[H])C([H])([H])C([H])([H])N2C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])=C(Cl)C(Cl)=C1[H]
[H]C1=C([H])C([H])=C2C(=C1[H])N(C(=O)C1=C([H])C([H])=C([H])C3=C([H])C([H])=C([H])C([H])=C13)C(=C2C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C([H])([H])[H]
[H]C1=C([H])C(\N=C2/SC([H])([H])C3(C([H])([H])N2C(=S)SC([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C3([H])[H])=C([H])C(OC([H])([H])[H])=C1[H]
[H]C1=C([H])C(OC([H])([H])C([H])([H])[H])=C(\N=C2/SC([H])([H])C3(C([H])([H])N2C(=S)SC([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C3([H])[H])C([H])=C1[H]
[H]N(C(=O)C1=C([H])N=C(N=C1C(F)(F)F)N([H])C1=C(Cl)C(Cl)=C([H])C([H])=C1[H])C([H])([H])C1([H])C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]N(C1=NC([H])=C(C(=O)N([H])C([H])([H])C2=C([H])C([H])=C(F)C([H])=C2[H])C(=N1)C(F)(F)F)C1=C([H])C(Cl)=C([H])C([H])=C1[H]
[H]N(C1=NC([H])=C(C(=O)N([H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C(=N1)C(F)(F)F)C1=C(Cl)C([H])=C([H])C([H])=C1[H]
[H]N(C1=NC([H])=C(C(=O)N([H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C(=N1)C(F)(F)F)C1=C(OC([H])([H])[H])C([H])=C([H])C([H])=C1[H]
[H]C1=C([H])C(\N=C2/SC([H])([H])C3(C([H])([H])N2C(=S)SC([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C3([H])[H])=C([H])C([H])=C1OC(F)(F)F
[H]C1=C([H])C(=C([H])C([H])=C1\N=C1/SC([H])([H])C2(C([H])([H])N1C(=S)SC([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C(F)(F)F
[H]C1=C([H])C(\N=C2/SC([H])([H])C3(C([H])([H])N2C(=S)SC([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C3([H])[H])=C([H])C(=C1[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])C(\N=C2/SC([H])([H])C3(C([H])([H])N2C(=S)SC([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C3([H])[H])=C([H])C([H])=C1OC([H])([H])[H]
[H]N(C(=O)C(\[H])=C(/[H])\C(\[H])=C(/[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C1=NC([H])=C(C(=O)N([H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C(=N1)C(F)(F)F)C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]N(C(=O)C1=C([H])N=C(N=C1C(F)(F)F)N([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C([H])O1
[H]C1=C([H])C([H])=C(O1)C([H])([H])OC(=O)C1=C([H])N=C(N=C1C(F)(F)F)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]N(C1=NC([H])=C(C(=O)N([H])C([H])([H])C2([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C(=N1)C(F)(F)F)C1=C([H])C(Cl)=C([H])C([H])=C1[H]
[H]N(C1=NC([H])=C(C(=O)N([H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C(=N1)C(F)(F)F)C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]N(C1=NC([H])=C(C(=O)N([H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C(=N1)C(F)(F)F)C1=C([H])C(Br)=C([H])C([H])=C1[H]
[H]N(C(=O)C1=C([H])N=C(N=C1C(F)(F)F)N([H])C1=C(Cl)C([H])=C([H])C(Cl)=C1[H])C([H])([H])C1([H])C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]N(C(=O)C1=C([H])N=C(N=C1C(F)(F)F)N([H])C1=C([H])C(Cl)=C(Cl)C([H])=C1[H])C([H])([H])C1([H])C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]N(C(=O)C1=C([H])N=C(N=C1C(F)(F)F)N([H])C1=C([H])C(Cl)=C([H])C([H])=C1[H])C([H])([H])C1([H])C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]N(C(=O)C1=C([H])N=C(N=C1C(F)(F)F)N([H])C1=C(F)C(Cl)=C([H])C([H])=C1[H])C([H])([H])C1([H])C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]N(C(=O)C1=C([H])N=C(N=C1C(F)(F)F)N([H])C1=C([H])C([H])=C(C#N)C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC1=C([H])C(=C([H])C(O[H])=C1C1=C([H])C(=C([H])C(=C1[H])C([H])([H])[H])C([H])([H])[H])C(=O)OC([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]OC1=C([H])C(=C([H])C(O[H])=C1C1=C([H])C(=C([H])C(=C1[H])C([H])([H])[H])C([H])([H])[H])C(=O)OC([H])([H])[H]
[H]OC1=C([H])C(=C([H])C(O[H])=C1C1=C([H])C(=C([H])C(=C1[H])C([H])([H])[H])C([H])([H])[H])C(=O)OC([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]O[C@@]1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@]1([H])N([H])C(=O)C1=C(N(C(=N1)C1=C([H])C([H])=C([H])C([H])=C1Cl)C1=C([H])C([H])=C(Cl)C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]O[C@@]1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@]1([H])N([H])C(=O)C1=C(N(C(=N1)C1=C([H])C([H])=C([H])C([H])=C1Cl)C1=C([H])C([H])=C(Br)C([H])=C1[H])C([H])([H])C([H])([H])[H]
[H]N(C(=O)C1=C([H])N(C(=N1)C1=C([H])C([H])=C([H])C([H])=C1Cl)C1=C([H])C([H])=C(Cl)C([H])=C1[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]OC1=C(C([H])=C([H])C(=C1[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C([H])([H])C(=O)OC([H])([H])[H])C1=C([H])C(=C([H])C(=C1[H])C([H])([H])[H])C([H])([H])[H]
[H]OC(=O)C(C1=C([H])C(O[H])=C(C([H])=C1[H])C1=C([H])C(=C([H])C(=C1[H])C([H])([H])[H])C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]OC(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C(C1=C([H])C(O[H])=C(C([H])=C1[H])C1=C([H])C(=C([H])C(=C1[H])C([H])([H])[H])C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)C1=C([H])N=C(N=C1C(F)(F)F)N([H])C1=C(Cl)C([H])=C(F)C([H])=C1[H])C([H])([H])C1([H])C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]N(C(=O)C1=C([H])N=C(N=C1C(F)(F)F)N([H])C1=C([H])C(Cl)=C([H])C([H])=C1[H])C([H])([H])C1([H])C([H])([H])C([H])([H])N([H])C([H])([H])C1([H])[H]
[H]N(C(=O)C1=C([H])N=C(N=C1C(F)(F)F)N([H])C1=C([H])C(Cl)=C([H])C(Cl)=C1[H])C([H])([H])C1([H])C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]C1=C([H])C(=C([H])C(=C1[H])C(=O)\N=C1/SC(=C(N1C([H])([H])[H])C([H])([H])[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C(F)(F)F
[H]C1=C([H])C(=C(Cl)C(=C1[H])C(=O)\N=C1/SC(=C(N1C([H])([H])C1([H])C([H])([H])C1([H])[H])C([H])([H])[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C(F)(F)F
[H]C1=C([H])C(=C([H])C(=C1[H])C(=O)\N=C1/SC(=C(N1C([H])([H])C([H])([H])OC([H])([H])[H])C([H])([H])[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C(F)(F)F
[H]C1=C(C([H])=C(C(=O)\N=C2/SC(=C(N2C([H])([H])C2([H])C([H])([H])C2([H])[H])C([H])([H])[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C(=C1[H])C([H])([H])[H])C(F)(F)F
[H]N(C(=O)C1=C([H])C(=C(C([H])=C1[H])C([H])([H])[H])S(=O)(=O)N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C1=C(C([H])=C([H])C([H])=C1[H])C(F)(F)F
[H]C1=C([H])C(=C(C([H])=C1C(=O)N1C([H])([H])C([H])([H])[C@]2([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@@]2([H])C1([H])[H])S(=O)(=O)N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])[H]
[H]C1=C([H])C(=C(C([H])=C1C(=O)N1C([H])([H])C([H])([H])[C@]2([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@@]2([H])C1([H])[H])S(=O)(=O)N1C([H])([H])C([H])([H])SC([H])([H])C1([H])[H])C([H])([H])[H]
[H]N(C(=O)C1=C([H])C(=C(C([H])=C1[H])C([H])([H])[H])S(=O)(=O)N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C1(C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])S(=O)(=O)C1=C(C([H])=C([H])C(=C1[H])C(=O)N1C([H])([H])C([H])([H])[C@]2([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@@]2([H])C1([H])[H])C([H])([H])[H]
[H]C1=NC2=C(OC(=O)C3=C([H])C(=C(C([H])=C3[H])C([H])([H])[H])S(=O)(=O)N3C([H])([H])C([H])([H])C([H])([H])C([H])([H])C3([H])[H])C([H])=C([H])C([H])=C2C([H])=C1[H]
[H]N(C(=O)C1=C([H])C(=C(C([H])=C1[H])C([H])([H])[H])S(=O)(=O)N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C1=NC2=C([H])C([H])=C([H])C([H])=C2C([H])=C1[H]
[H]C1=C([H])C(=C(C([H])=C1C(=O)N1C([H])([H])C([H])([H])[C@]2([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@@]2([H])C1([H])[H])S(=O)(=O)N1C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])C(=C(C([H])=C1C(=O)N1C([H])([H])C([H])([H])[C@]2([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@@]2([H])C1([H])[H])S(=O)(=O)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C([H])([H])[H]
[H]N(C(=O)C1=C([H])C(=C(C([H])=C1[H])C([H])([H])[H])S(=O)(=O)N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C1=C(OC([H])([H])[H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)C1=C([H])C(=C(C([H])=C1[H])C([H])([H])[H])S(=O)(=O)N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)C1=C([H])C(=C(C([H])=C1[H])C([H])([H])[H])S(=O)(=O)N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C([H])C2=C([H])C([H])=C([H])N=C12
[H]OC1([H])C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])S(=O)(=O)C1=C(C([H])=C([H])C(=C1[H])C(=O)N1C([H])([H])C([H])([H])[C@]2([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@@]2([H])C1([H])[H])C([H])([H])[H]
[H]N(C(=O)C1=C([H])C(=C(C([H])=C1[H])C([H])([H])[H])S(=O)(=O)N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])[C@@]([H])(C([H])([H])[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(C(=O)C1=C([H])C(=C(C([H])=C1[H])C([H])([H])[H])S(=O)(=O)N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C1=C(C([H])=C([H])C([H])=C1[H])S(=O)(=O)C([H])([H])[H]
[H]C1=C([H])C(=C(C([H])=C1C(=O)N1C([H])([H])C([H])([H])[C@]2([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@@]2([H])C1([H])[H])S(=O)(=O)N1C([H])([H])C([H])([H])C1([H])[H])C([H])([H])[H]
[H]C1=C([H])C(=C([H])C(=C1Cl)S(=O)(=O)N1C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C(=O)N1C([H])([H])C([H])([H])[C@]2([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@@]2([H])C1([H])[H]
[H]N(C(=O)C1=C([H])C(=C(Cl)C([H])=C1[H])S(=O)(=O)N1C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]C1=C(Cl)C(=C([H])C(=C1[H])C(F)(F)F)C(=O)\N=C1/SC(=C(N1C([H])([H])C1([H])C([H])([H])C1([H])[H])C([H])([H])[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]C1=C(N(C([H])([H])[H])C([H])([H])[H])C(=C([H])C(=C1[H])C(F)(F)F)C(=O)\N=C1/SC(=C(N1C([H])([H])C1([H])C([H])([H])C1([H])[H])C([H])([H])[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])C(OC(F)(F)F)=C([H])C(=C1[H])C(=O)\N=C1/SC(=C(N1C([H])([H])C1([H])C([H])([H])C1([H])[H])C([H])([H])[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]C1=C(OC([H])([H])[H])C(=C([H])C(=C1[H])C(F)(F)F)C(=O)\N=C1/SC(=C(N1C([H])([H])C1([H])C([H])([H])C1([H])[H])C([H])([H])[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])C(=C([H])C(=C1[H])C(=O)\N=C1/SC(C(=O)N(C([H])([H])[H])C([H])([H])[H])=C(N1C([H])([H])C1([H])C([H])([H])C1([H])[H])C([H])([H])[H])C(F)(F)F
[H]C1=C([H])C(=C([H])C(=C1[H])C(=O)\N=C1/SC(C(=O)OC([H])([H])C([H])([H])[H])=C(N1C([H])([H])C1([H])C([H])([H])C1([H])[H])C([H])([H])[H])C(F)(F)F
[H]C1=C([H])C(=C([H])C(=C1[H])C(=O)\N=C1/SC(=C(N1C([H])([H])C1([H])C([H])([H])C1([H])[H])C([H])([H])[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])N(C([H])([H])[H])C([H])([H])[H]
[H]N(C1=NC([H])=C(C(=O)N([H])C([H])([H])C2([H])C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])C(=N1)C(F)(F)F)C1=C(F)C([H])=C(F)C([H])=C1[H]
[H]N(C(=O)C1=C([H])N=C(N=C1C(F)(F)F)N([H])C1=C(F)C([H])=C(Cl)C([H])=C1[H])C([H])([H])C1([H])C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]C1=C([H])C(OC(F)(F)F)=C(\N=C2/SC([H])([H])C3(C([H])([H])N2C(=S)SC([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C3([H])[H])C([H])=C1[H]
[H]C1=C([H])C(=C([H])C([H])=C1\N=C1/SC([H])([H])C2(C([H])([H])N1C(=S)SC([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]C1=C([H])C(\N=C2/SC([H])([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])N2C(=S)SC([H])([H])[H])=C(C([H])=C1[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])C2=NON=C2C(\N=C2/SC([H])([H])C3(C([H])([H])N2C(=S)SC([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C3([H])[H])=C1[H]
[H]C1=C([H])C(\N=C2/SC([H])([H])C3(C([H])([H])N2C(=S)SC([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C3([H])[H])=C2C(=C1[H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H]
[H]C1=C([H])C2=C(C([H])=C1\N=C1/SC([H])([H])C3(C([H])([H])N1C(=S)SC([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C3([H])[H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H]
[H]N(C1=NC([H])=C(C(=O)N([H])C([H])([H])C2([H])C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])C(=N1)C(F)(F)F)C1=C(F)C(F)=C([H])C([H])=C1[H]
[H]N(C(=O)C1=C([H])N=C(N=C1C(F)(F)F)N([H])C1=C(Cl)C([H])=C(Cl)C([H])=C1[H])C([H])([H])C1([H])C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]N(C(=O)C1=C([H])N=C(N=C1C(F)(F)F)N([H])C1=C([H])C(Cl)=C([H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]OC1=C(C([H])=C([H])C(=C1[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C([H])([H])C(=O)N([H])C([H])([H])[H])C1=C([H])C(=C([H])C(=C1[H])C([H])([H])[H])C([H])([H])[H]
[H]N([H])C1=C(C([H])=C([H])C(=C1[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C1=C([H])C(=C([H])C(=C1[H])C([H])([H])[H])C([H])([H])[H]
[H]OC1=C(C([H])=C([H])C(=C1[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C(=O)OC([H])([H])[H])C1=C([H])C(=C([H])C(=C1[H])C([H])([H])[H])C([H])([H])[H]
[H]OC1=C(C([H])=C([H])C(=C1[H])C(C(=O)N([H])C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C1=C([H])C(=C([H])C(=C1[H])C([H])([H])[H])C([H])([H])[H]
[H]OC1=C(C([H])=C([H])C(=C1[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C1=C([H])C(N([H])[H])=C([H])C([H])=C1[H]
[H]OC1=C(C([H])=C([H])C(=C1[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C1=C(OC([H])([H])[H])C([H])=C([H])C([H])=C1[H]
[H]OC1=C(C([H])=C([H])C(=C1[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C1=C([H])C([H])=C(C#N)C([H])=C1[H]
[H]C1=C([H])C([H])=C2C(\N=C3/SC([H])([H])C4(C([H])([H])N3C(=S)SC([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C4([H])[H])=C([H])C([H])=C([H])C2=C1[H]
[H]C1=C([H])C(\N=C2/SC([H])([H])C3(C([H])([H])N2C(=S)SC([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C3([H])[H])=C2C(=C1[H])C([H])([H])C([H])([H])C2([H])[H]
[H]C1=C([H])C(C#N)=C([H])C([H])=C1\N=C1/SC([H])([H])C2(C([H])([H])N1C(=S)SC([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H]
[H]C1=C([H])C(OC([H])([H])[H])=C(\N=C2/SC([H])([H])C3(C([H])([H])N2C(=S)SC([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C3([H])[H])C([H])=C1[H]
[H]C1=C([H])C(=C([H])C([H])=C1\N=C1/SC([H])([H])C2(C([H])([H])N1C(=S)SC([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C([H])([H])[H]
[H]C1=C([H])C(\N=C2/SC([H])([H])C(C([H])([H])C([H])([H])[H])(C([H])([H])C([H])([H])[H])C([H])([H])N2C(=S)SC([H])([H])[H])=C(C([H])=C1[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])C(=C([H])C(=C1C1=C([H])C(=C([H])C(=C1[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]C1=C([H])C(=C([H])C([H])=C1C1=C([H])C(=C([H])C(=C1[H])C([H])([H])[H])C([H])([H])[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]OC1=C(C([H])=C([H])C(=C1[H])C(C(=O)OC([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C1=C([H])C(=C([H])C(=C1[H])C([H])([H])[H])C([H])([H])[H]
[H]N([H])C([H])([H])C1=C(C([H])=C([H])C(=C1[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C1=C([H])C(=C([H])C(=C1[H])C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)C1=C(C([H])=C([H])C(=C1[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C1=C([H])C(=C([H])C(=C1[H])C([H])([H])[H])C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])C(=C([H])C(C(=O)OC([H])([H])[H])=C1C1=C([H])C(=C([H])C(=C1[H])C([H])([H])[H])C([H])([H])[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]OC1=C(C([H])=C([H])C(=C1[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C1=C(C([H])=C([H])C(=C1[H])C([H])([H])[H])C([H])([H])[H]
[H]OC1=C(C([H])=C([H])C(=C1[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C1=C(C([H])=C([H])C([H])=C1C([H])([H])[H])C([H])([H])[H]
[H]OC1=C(C([H])=C([H])C(=C1[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C1=C([H])C(=C(C([H])=C1[H])C([H])([H])[H])C([H])([H])[H]
[H]OC1=C(C([H])=C([H])C(=C1[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C1=C(C(=C([H])C([H])=C1[H])C([H])([H])[H])C([H])([H])[H]
[H]OC1=C(C([H])=C([H])C(=C1[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C(=O)N([H])C([H])([H])[H])C1=C([H])C(=C([H])C(=C1[H])C([H])([H])[H])C([H])([H])[H]
[H]OC1=C(C([H])=C([H])C(=C1[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C1=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]OC1=C(C([H])=C([H])C(=C1[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C1=C([H])C(OC([H])([H])[H])=C([H])C([H])=C1[H]
[H]OC1=C(C([H])=C([H])C(=C1[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])O[H])C1=C([H])C(=C([H])C(=C1[H])C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C(=O)\N=C1/SC(=C(N1C([H])([H])C1([H])C([H])([H])C1([H])[H])C([H])([H])[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]C1=C(F)C(=C([H])C(=C1[H])C(F)(F)F)C(=O)\N=C1/SC(=C(N1C([H])([H])C1([H])C([H])([H])C1([H])[H])C([H])([H])[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])C(Br)=C([H])C(=C1[H])C(=O)\N=C1/SC(=C(N1C([H])([H])C1([H])C([H])([H])C1([H])[H])C([H])([H])[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])C(Cl)=C([H])C(=C1[H])C(=O)\N=C1/SC(=C(N1C([H])([H])C1([H])C([H])([H])C1([H])[H])C([H])([H])[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])C(=C([H])C(=C1[H])C(=O)\N=C1/SC(=C(N1C([H])([H])C([H])([H])OC([H])([H])C([H])([H])[H])C([H])([H])[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C(F)(F)F
[H]C1=C([H])C(=C([H])C(=C1[H])C(=O)\N=C1/SC(=C(N1C([H])([H])C1([H])C([H])([H])C1([H])[H])C([H])([H])[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C(F)(F)F
[H]C1=C([H])C(=C([H])C(=C1[H])C(=O)\N=C1/SC(=C(N1C([H])([H])C([H])([H])[H])C([H])([H])[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C(F)(F)F
[H]C1=C([H])C(=C([H])C(=C1[H])C(=O)\N=C1/SC(=C(N1C([H])([H])C1([H])C([H])([H])C1([H])[H])C([H])([H])[H])C([H])([H])[H])C(F)(F)F
[H]C1=C([H])C(=C([H])C(=C1[H])C(=O)\N=C1/SC(=C(N1C([H])([H])C1([H])C([H])([H])C1([H])[H])C([H])([H])[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])C(OC([H])([H])[H])=C([H])C(=C1[H])C(=O)\N=C1/SC(=C(N1C([H])([H])C1([H])C([H])([H])C1([H])[H])C([H])([H])[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])C(C(=O)\N=C2/SC(=C(N2C([H])([H])C2([H])C([H])([H])C2([H])[H])C([H])([H])[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])=C(C([H])=C1[H])C(F)(F)F
[H]C1=C([H])C(=C([H])C(=C1[H])C(=O)\N=C1/SC(=C(N1C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C(F)(F)F
[H]C1=C([H])C(=C([H])C(=C1[H])C(=O)\N=C1/SC(=C(N1C([H])([H])C1([H])C([H])([H])C1([H])[H])C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])C(F)(F)F
[H]C1=C([H])C2=C([H])C([H])=C([H])C(=C2C([H])=C1[H])S(=O)(=O)\N=C1/SC(=C(N1C([H])([H])C1([H])C([H])([H])C1([H])[H])C([H])([H])[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)\N=C1/SC(=C(N1C([H])([H])[H])C([H])([H])[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]C([H])=C([H])C([H])([H])N1\C(SC(=C1C([H])([H])[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])=N\S(=O)(=O)C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)\N=C1/SC(=C(N1C([H])([H])C1([H])C([H])([H])C1([H])[H])C([H])([H])[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]C(=C(C([H])([H])[H])C([H])([H])[H])C([H])([H])N1\C(SC(=C1C([H])([H])[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])=N\S(=O)(=O)C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C#CC([H])([H])N1\C(SC(=C1C([H])([H])[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])=N\S(=O)(=O)C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)C1=C([H])N=C(N=C1C(F)(F)F)N([H])C1=C([H])C(C#N)=C([H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC1(C([H])([H])N([H])C(=O)C2=C([H])N=C(N=C2C(F)(F)F)N([H])C2=C([H])C(Cl)=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(C(=O)C1=C([H])N=C(N=C1C(F)(F)F)N([H])C1=C(F)C([H])=C([H])C(Cl)=C1[H])C([H])([H])C1([H])C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]N(C(=O)C1=C([H])N=C(N=C1C(F)(F)F)N([H])C1=C(Cl)C([H])=C([H])C([H])=C1Cl)C([H])([H])C1([H])C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]N(C1=NC([H])=C(C(=O)N([H])C([H])([H])C2([H])C([H])([H])C2([H])[H])C(=N1)C(F)(F)F)C1=C([H])C(Cl)=C([H])C([H])=C1[H]
[H]N(C1=NC([H])=C(C(=O)N([H])C([H])([H])C2=C([H])C([H])=C(Cl)C([H])=C2[H])C(=N1)C(F)(F)F)C1=C([H])C(Cl)=C([H])C([H])=C1[H]
[H]C1=C([H])C(OC([H])([H])[H])=C(\N=C2/SC([H])([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])N2C(=S)SC([H])([H])[H])C([H])=C1[H]
[H]C1=C([H])C(\N=C2/SC([H])([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])N2C(=O)OC([H])([H])C([H])([H])[H])=C(C([H])=C1[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])C(OC([H])([H])C([H])([H])[H])=C(\N=C2/SC([H])([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])N2C(=S)SC([H])([H])[H])C([H])=C1[H]
[H]C1=C([H])C(\N=C2/SC([H])([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])N2C(=S)SC([H])([H])C([H])([H])[H])=C(C([H])=C1[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]OC([H])([H])[C@]([H])(N([H])C(=O)C([H])([H])C([H])([H])C([H])([H])C(\[H])=C(\[H])C([H])([H])C(\[H])=C(\[H])C([H])([H])C([H])([H])OC1=C([H])C([H])=C([H])C(=C1[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])Br)C([H])([H])[H]
[H]OC([H])([H])C([H])([H])C([H])([H])C([H])([H])C(C1=C([H])C(OC([H])([H])C([H])([H])C(\[H])=C(\[H])C([H])([H])C(\[H])=C(\[H])C([H])([H])C([H])([H])C([H])([H])C(=O)N([H])[C@]([H])(C([H])([H])[H])C([H])([H])O[H])=C([H])C([H])=C1[H])(C([H])([H])[H])C([H])([H])[H]
[H]\C(=C(\[H])[C@]1([H])[C@]2([H])[C@]([H])(OC(=O)[C@]2([H])C([H])([H])[C@]2([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@@]12[H])C([H])([H])[H])C1=C([H])C([H])=C(C([H])=N1)N1C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]OC1=C([H])C(=C([H])C2=C1[C@]1([H])C([H])([H])C(=C([H])C([H])([H])[C@@]1([H])C(O2)(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])[C@]1(C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C1(Br)Br
[H]OC1=C([H])C(=C([H])C(O[H])=C1[C@]1([H])C([H])=C(C([H])([H])[H])C([H])([H])C([H])([H])[C@]1([H])C(=C([H])[H])C([H])([H])[H])C1(SC([H])([H])C([H])([H])S1)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]OC1=C2C(OC(C([H])([H])[H])(C([H])([H])[H])[C@]3([H])C([H])([H])C([H])=C(C([H])([H])[H])C([H])([H])[C@@]23[H])=C([H])C(=C1[H])C1=C2C([H])=C([H])C([H])=C([H])C2=C([H])C([H])=C1[H]
[H]OC([H])([H])[C@]([H])(N([H])C(=O)C([H])([H])C([H])([H])C([H])([H])C(\[H])=C(\[H])C([H])([H])C(\[H])=C(\[H])C([H])([H])C([H])([H])OC1=C([H])C([H])=C([H])C(=C1[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N=[N+]=[N-])C([H])([H])[H]
[H]OC([H])([H])[C@]([H])(N([H])C(=O)C([H])([H])C([H])([H])C([H])([H])C(\[H])=C(\[H])C([H])([H])C(\[H])=C(\[H])C([H])([H])C([H])([H])OC1=C([H])C([H])=C([H])C(=C1[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C#N)C([H])([H])[H]
[H]OC([H])([H])[C@]([H])(N([H])C(=O)C([H])([H])C([H])([H])C([H])([H])C(\[H])=C(\[H])C([H])([H])C(\[H])=C(\[H])C([H])([H])C([H])([H])OC1=C([H])C([H])=C(C([H])=C1[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])[H]
[H]OC([H])([H])[C@]([H])(N([H])C(=O)C([H])([H])C([H])([H])C([H])([H])C(\[H])=C(\[H])C([H])([H])C(\[H])=C(\[H])C([H])([H])C(\[H])=C(\[H])C1=C([H])C([H])=C([H])C([H])=C1C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])[H]
[H]OC([H])([H])[C@]([H])(N([H])C(=O)C([H])([H])C([H])([H])C([H])([H])C(\[H])=C(\[H])C([H])([H])C(\[H])=C(\[H])C([H])([H])C(\[H])=C(\[H])C([H])([H])C([H])([H])OC1=C([H])C([H])=C([H])C(=C1[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])[H]
[H]OC1=C([H])C(=C([H])C2=C1[C@]1([H])C([H])([H])C(=C([H])C([H])([H])[C@@]1([H])C(O2)(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C#N
[H]OC1=C2C(OC(C([H])([H])[H])(C([H])([H])[H])[C@]3([H])C([H])([H])C([H])=C(C([H])([H])[H])C([H])([H])[C@@]23[H])=C([H])C(=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])[H]
[H]OC1=C([H])C(=C([H])C2=C1[C@]1([H])C([H])([H])C(=C([H])C([H])([H])[C@@]1([H])C(O2)(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]C1=C([H])C(\N=C2/SC([H])([H])C([H])([H])C([H])([H])N2C(=S)SC([H])([H])[H])=C(C([H])=C1[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=S)N1\C(SC([H])([H])C(C([H])([H])[H])(C([H])([H])[H])C1([H])[H])=N\C1=C(C([H])=C([H])C([H])=C1[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])[H]
[H]C1=C([H])C(\N=C2/SC([H])([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])N2C(=S)SC([H])([H])[H])=C([H])C(=C1[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])C(=C(\N=C2/SC([H])([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])N2C(=S)SC([H])([H])[H])C(=C1[H])C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])C(\N=C2/S[C@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])N2C(=S)SC([H])([H])[H])=C(C([H])=C1[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])C(\N=C2/SC([H])([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])N2C([H])([H])C([H])([H])C([H])([H])[H])=C(C([H])=C1[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])C([H])=C(OC2=C(\N=C3/SC([H])([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])N3C(=S)SC([H])([H])[H])C([H])=C([H])C([H])=C2[H])C([H])=C1[H]
[H]C1=C([H])C(\N=C2/SC([H])([H])C([H])([H])[C@@]([H])(N2C(=S)SC([H])([H])[H])C([H])([H])[H])=C(C([H])=C1[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])C(\N=C2/SC([H])([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])N2C(=S)SC([H])([H])C([H])([H])C([H])([H])[H])=C(C([H])=C1[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]OC1=C([H])C(=C([H])C2=C1[C@]1([H])C([H])([H])C(=C([H])C([H])([H])[C@@]1([H])C(O2)(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C1([H])SC([H])([H])C([H])([H])S1
[H]OC1=C2C(OC(C([H])([H])[H])(C([H])([H])[H])[C@]3([H])C([H])([H])C([H])=C(C([H])([H])[H])C([H])([H])[C@@]23[H])=C([H])C(=C1[H])C1(C#N)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]OC1=C([H])C(=C([H])C(O[H])=C1[C@]1([H])C([H])=C(C([H])([H])[H])C([H])([H])C([H])([H])[C@]1([H])C(=C([H])[H])C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H]
[H]OC1=C([H])C(OC2=C([H])C([H])=C([H])C([H])=C2[H])=C([H])C2=C1[C@]1([H])C([H])([H])C(=C([H])C([H])([H])[C@@]1([H])C(O2)(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H]
[H]OC1=C([H])C(=C([H])C2=C1[C@]1([H])C([H])([H])C(=C([H])C([H])([H])[C@@]1([H])C(O2)(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C(=O)N([H])N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]C1=C([H])C(Cl)=C(\N=C2/SC([H])([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])N2C(=S)SC([H])([H])[H])C([H])=C1[H]
[H]C1=C([H])C(\N=C2/SC([H])([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])N2C(=S)OC([H])([H])C([H])([H])[H])=C(C([H])=C1[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)N1\C(SC([H])([H])C(C([H])([H])[H])(C([H])([H])[H])C1([H])[H])=N\C1=C(C([H])=C([H])C([H])=C1[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])[H]
[H]OC1=C(C([H])=C([H])C(=C1[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C1=C([H])C(C#N)=C([H])C([H])=C1[H]
[H]OC1=C([H])C(=C([H])C(O[H])=C1[C@]1([H])C([H])=C(C([H])([H])[H])C([H])([H])C([H])([H])[C@]1([H])C(=C([H])[H])C([H])([H])[H])[C@]1(C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C1(Cl)Cl
[H]OC1=C(C([H])=C([H])C(=C1[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C1=C(OC([H])([H])[H])C(OC([H])([H])[H])=C([H])C([H])=C1[H]
[H]OC(=O)C1=C(C([H])=C([H])C(=C1[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C1=C([H])C(=C([H])C(=C1[H])C([H])([H])[H])C([H])([H])[H]
[H]OC1=C(C([H])=C([H])C(=C1[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C1=C([H])C([H])=C([H])N=C1[H]
[H]N(C(=O)C1=C([H])N=C(N=C1C(F)(F)F)N([H])C1=C([H])C(Cl)=C([H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C(C#N)C([H])=C1[H]
[H]OC1=C([H])C(=C([H])C2=C1[C@]1([H])C([H])([H])C(=C([H])C([H])([H])[C@@]1([H])C(O2)(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C1(SC([H])([H])C([H])([H])C([H])([H])S1)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]OC1=C([H])C(=C([H])C(O[H])=C1[C@]1([H])C([H])=C(C([H])([H])[H])C([H])([H])C([H])([H])[C@]1([H])C(=C([H])[H])C([H])([H])[H])C1(C#N)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]OC1=C([H])C(=C([H])C2=C1[C@]1([H])C([H])([H])C(=C([H])C([H])([H])[C@@]1([H])C(O2)(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]C1=C([H])C(\N=C2/SC([H])([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])N2C([H])([H])C([H])([H])[H])=C(C([H])=C1[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])C(\N=C2/SC([H])([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])N2C(=S)SC([H])([H])[H])=C(C([H])=C1[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])C(F)=C(\N=C2/SC([H])([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])N2C(=S)SC([H])([H])[H])C([H])=C1[H]
[H]C1=C([H])C(\N=C2/SC([H])([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])N2C(=S)SC([H])([H])[H])=C(C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]C1=C([H])C(\N=C2/SC([H])([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])N2C(=O)SC([H])([H])C([H])([H])[H])=C(C([H])=C1[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C1=NC([H])=C(C(=O)N([H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C(=N1)C(F)(F)F)C1=C([H])C(Cl)=C([H])C([H])=C1[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1\C(SC([H])([H])C(C([H])([H])[H])(C([H])([H])[H])C1([H])[H])=N\C1=C(C([H])=C([H])C([H])=C1[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])C(\N=C2/SC([H])([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])N2C(=S)SC([H])([H])[H])=C(C([H])=C1[H])C(F)(F)F
[H]C1=C([H])C([H])=C(\N=C2/SC([H])([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])N2C(=S)SC([H])([H])[H])C([H])=C1[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C1=C(\N=C2/SC([H])([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])N2C(=S)SC([H])([H])[H])C([H])=C([H])C([H])=C1[H]
[H]OC1=C([H])C(=C([H])C2=C1[C@]1([H])C([H])([H])C(=C([H])C([H])([H])[C@@]1([H])C(O2)(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C(=C([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]OC1=C([H])C(=C([H])C2=C1[C@]1([H])C([H])([H])C(=C([H])C([H])([H])[C@@]1([H])C(O2)(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C1(SC2=C(S1)C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]OC1=C2C(OC(C([H])([H])[H])(C([H])([H])[H])[C@]3([H])C([H])([H])C([H])=C(C([H])([H])[H])C([H])([H])[C@@]23[H])=C([H])C(=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H]
[H]OC1=C([H])C(=C([H])C2=C1[C@]1([H])C([H])([H])C(=C([H])C([H])([H])[C@@]1([H])C(O2)(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])OC1=C([H])C([H])=C(C#N)C([H])=C1[H]
[H]OC1=C([H])C(=C([H])C2=C1[C@]1([H])C([H])([H])C(=C([H])C([H])([H])[C@@]1([H])C(O2)(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])[C@]1(C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C1(Cl)Cl
[H]OC1=C([H])C(=C([H])C2=C1[C@]1([H])C([H])([H])C(=C([H])C([H])([H])[C@@]1([H])C(O2)(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C1(S[C@]([H])(C([H])([H])[H])[C@]([H])(S1)C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]OC1=C([H])C(=C([H])C(O[H])=C1[C@]1([H])C([H])=C(C([H])([H])[H])C([H])([H])C([H])([H])[C@]1([H])C(=C([H])[H])C([H])([H])[H])[C@@]1(C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C1(Br)Br
[H]OC1=C([H])C(=C([H])C(O[H])=C1[C@]1([H])C([H])=C(C([H])([H])[H])C([H])([H])C([H])([H])[C@]1([H])C(=C([H])[H])C([H])([H])[H])C1(C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]OC1=C([H])C(=C([H])C(O[H])=C1[C@]1([H])C([H])=C(C([H])([H])[H])C([H])([H])C([H])([H])[C@]1([H])C(=C([H])[H])C([H])([H])[H])C1=C([H])C([H])=C([H])C2=C([H])C([H])=C([H])C([H])=C12
[H]OC1=C([H])C(=C([H])C(O[H])=C1[C@]1([H])C([H])=C(C([H])([H])[H])C([H])([H])C([H])([H])[C@]1([H])C(=C([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]C1=C([H])C(Br)=C(\N=C2/SC([H])([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])N2C(=S)SC([H])([H])[H])C([H])=C1[H]
[H]N1\C(SC([H])([H])C(C([H])([H])[H])(C([H])([H])[H])C1([H])[H])=N\C1=C(C([H])=C([H])C([H])=C1[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])C(=C([H])C([H])=C1\N=C1/SC([H])([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])N1C(=S)SC([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]C1=C(Cl)C(=C([H])C(=C1[H])C(=O)\N=C1/SC(=C(N1C([H])([H])C1([H])C([H])([H])C1([H])[H])C([H])([H])[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C(F)(F)F
[H]N(C1=NC([H])=C(C(=O)N([H])C([H])([H])C2=C([H])C(Cl)=C([H])C([H])=C2[H])C(=N1)C(F)(F)F)C1=C([H])C(Cl)=C([H])C([H])=C1[H]
[H]N(C1=NC([H])=C(C(=O)N([H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C(=N1)C(F)(F)F)C1=C([H])C(OC([H])([H])[H])=C([H])C([H])=C1[H]
[H]OC1=C([H])C(=C([H])C2=C1[C@]1([H])C([H])([H])C(=C([H])C([H])([H])[C@@]1([H])C(O2)(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C1(OC([H])([H])C([H])([H])O1)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]C1=C([H])C(\N=C2/SC([H])([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])N2C(=S)SC([H])([H])[H])=C(C([H])=C1[H])C([H])([H])[H]
[H]C1=C([H])C(\N=C2/SC([H])([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])N2C(=O)C([H])([H])C([H])([H])[H])=C(C([H])=C1[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C1=NC([H])=C(C(=O)N([H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C(=N1)C(F)(F)F)C1=C([H])C(F)=C([H])C([H])=C1[H]
[H]N(C1=NC([H])=C(C(=O)N([H])C([H])([H])C2([H])C([H])([H])C([H])([H])C2([H])[H])C(=N1)C(F)(F)F)C1=C([H])C(Cl)=C([H])C([H])=C1[H]
[H]N(C1=NC([H])=C(C(=O)N([H])C([H])([H])C2([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C(=N1)C(F)(F)F)C1=C([H])C(Cl)=C([H])C([H])=C1[H]
[H]C1=C([H])C(\N=C2/SC([H])([H])C3(C([H])([H])N2C(=S)SC([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C3([H])[H])=C(C(=C1[H])C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])C(\N=C2/SC([H])([H])C3(C([H])([H])C([H])([H])C([H])([H])C3([H])[H])C([H])([H])N2C(=S)SC([H])([H])[H])=C(C([H])=C1[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])C(\N=C2/SC([H])([H])C3(C([H])([H])N2C(=S)SC([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C3([H])[H])=C(C([H])=C1[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])C2=NSN=C2C(\N=C2/SC([H])([H])C3(C([H])([H])N2C(=S)SC([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C3([H])[H])=C1[H]
[H]C1=C([H])C(\N=C2/SC([H])([H])C3(C([H])([H])C3([H])[H])C([H])([H])N2C(=S)SC([H])([H])[H])=C(C([H])=C1[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])C(\N=C2/SC([H])([H])C3(C([H])([H])N2C(=S)SC([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C3([H])[H])=C2C(=C1[H])N(C([H])([H])[H])C([H])([H])C([H])([H])C2([H])[H]
[H]C1=C([H])C(\N=C2/SC([H])([H])C3(C([H])([H])N2C(=S)SC([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C3([H])[H])=C(C([H])=C1[H])C(F)(F)F
[H]C1=NC2=C([H])C([H])=C([H])C(\N=C3/SC([H])([H])C4(C([H])([H])N3C(=S)SC([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C4([H])[H])=C2C([H])=C1[H]
[H]N(C(=O)C1=C([H])C(=C(C([H])=C1[H])C([H])([H])[H])S(=O)(=O)N1C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(C(=O)C1=C([H])C(=C(C([H])=C1[H])C([H])([H])[H])S(=O)(=O)N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C1=C(C([H])=C([H])C([H])=C1[H])C([H])([H])[H]
[H]N(C(=O)C1=C([H])C(=C(C([H])=C1[H])C([H])([H])[H])S(=O)(=O)N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1C([H])([H])C2=C(C3=C([H])C(=C([H])C([H])=C3N2S(=O)(=O)C([H])([H])C([H])([H])[H])C(=O)N2C([H])([H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])C2([H])[H])C1([H])[H]
[H]C1=C2N(C3=C(C2=C([H])C(=C1[H])C(=O)N(C([H])([H])[H])C([H])([H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])N(C3([H])[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])S(=O)(=O)C([H])([H])C([H])([H])[H]
[H]C1=C([H])C(=C(C([H])=C1C(=O)N1C([H])([H])C([H])([H])[C@]2([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@@]2([H])C1([H])[H])S(=O)(=O)N1C([H])([H])C([H])([H])S(=O)(=O)C([H])([H])C1([H])[H])C([H])([H])[H]
[H]N(C(=O)C1=C([H])C(=C(C([H])=C1[H])C([H])([H])[H])S(=O)(=O)N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C([H])C(Cl)=C1[H]
[H]C1=C([H])C(=C(C([H])=C1C(=O)N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])S(=O)(=O)N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])[H]
[H]N(C([H])(C([H])([H])[H])C([H])([H])[H])S(=O)(=O)C1=C(C([H])=C([H])C(=C1[H])C(=O)N1C([H])([H])C([H])([H])[C@]2([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@@]2([H])C1([H])[H])C([H])([H])[H]
[H]C1=C([H])C(=C(C([H])=C1C(=O)N1C([H])([H])C([H])([H])[C@]2([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@@]2([H])C1([H])[H])S(=O)(=O)N1C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)C1=C([H])N(C2=C([H])C(Cl)=C([H])C([H])=C2C1=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])[C@@]([H])(C([H])([H])[H])[C@]12C([H])([H])[C@@]3([H])C([H])([H])[C@]([H])(C([H])([H])[C@]([H])(C3([H])[H])C1([H])[H])C2([H])[H]
[H]C1=C([H])C2=C([H])C3=C([H])C([H])=C([H])C([H])=C3C(C(=O)C3=C([H])N(C4=C([H])C([H])=C([H])C([H])=C4C3=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])=C2C([H])=C1[H]
[H]N(C(=O)C1=C(N(C2=C([H])C([H])=C([H])C([H])=C2C1=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])[H])[C@]([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H]
[H]N(C(=O)C1=C([H])N(C2=C([H])C([H])=C(Cl)C([H])=C2C1=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])[C@]1([H])C2=C(C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(C(=O)C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])N(C2=C([H])C([H])=C([H])C([H])=C2C1=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]N(C(=O)C1=C([H])N(C2=C([H])C([H])=C([H])C([H])=C2C1=S)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])[C@]12C([H])([H])[C@]3([H])C([H])([H])[C@](C([H])([H])[H])(C1([H])[H])C([H])([H])[C@@](C([H])([H])[H])(C3([H])[H])C2([H])[H]
[H]N(C([H])([H])C1=C([H])N(C2=C([H])C([H])=C([H])C([H])=C2C1=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])[C@]1([H])C2=C(C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(C([H])([H])C1=C([H])N(C2=C([H])C([H])=C([H])C([H])=C2C1=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)C1=C(N(C2=C([H])C([H])=C([H])C([H])=C2C1=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])[H])[C@]12C([H])([H])[C@]3([H])C([H])([H])[C@](C([H])([H])[H])(C1([H])[H])C([H])([H])[C@@](C([H])([H])[H])(C3([H])[H])C2([H])[H]
[H]N(C([H])([H])C1=C([H])N(C2=C([H])C([H])=C([H])C([H])=C2C1=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])[C@]12C([H])([H])[C@@]3([H])C([H])([H])[C@]([H])(C([H])([H])[C@]([H])(C3([H])[H])C1([H])[H])C2([H])[H]
[H]N(C(=O)C1=C2C([H])=C([H])C([H])=C([H])C2=C([H])C([H])=C1[H])C1=C([H])N(C2=C([H])C([H])=C([H])C([H])=C2C1=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]N(C(=O)C1=C([H])N(C2=C([H])C(Cl)=C([H])C([H])=C2C1=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])[C@]12C([H])([H])[C@]3([H])C([H])([H])[C@](C([H])([H])[H])(C1([H])[H])C([H])([H])[C@@](C([H])([H])[H])(C3([H])[H])C2([H])[H]
[H]N(C(=O)C1=C([H])N(C2=C([H])C([H])=C([H])C([H])=C2C1=O)C([H])([H])C1=C([H])C([H])=C(F)C([H])=C1[H])[C@]12C([H])([H])[C@]3([H])C([H])([H])[C@](C([H])([H])[H])(C1([H])[H])C([H])([H])[C@@](C([H])([H])[H])(C3([H])[H])C2([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1C([H])=C(C(=O)C2=C([H])C([H])=C([H])C3=C([H])C([H])=C([H])C([H])=C23)C(=O)C2=C([H])C([H])=C([H])C([H])=C12
[H]C1=C([H])C([H])=C2C(C([H])=C([H])C([H])=C2C(=O)C2=C([H])N(C3=C([H])C([H])=C([H])C([H])=C3C2=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])=C1[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])N1C([H])=C(C(=O)C2=C([H])C([H])=C([H])C3=C([H])C([H])=C([H])C([H])=C23)C(=O)C2=C([H])C([H])=C([H])C([H])=C12
[H]C1=C([H])C([H])=C2C(C([H])=C([H])C([H])=C2C(=O)C2=C([H])N(C3=C([H])C([H])=C([H])C([H])=C3C2=O)C([H])([H])C([H])([H])C2([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])=C1[H]
[H]N(C(=O)C1=C(N(C2=C([H])C([H])=C([H])C([H])=C2C1=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])[H])[C@]([H])(C1=C2C([H])=C([H])C([H])=C([H])C2=C([H])C([H])=C1[H])C([H])([H])[H]
[H]OC1=C([H])C(=C([H])C2=C1[C@]1([H])C([H])=C(C([H])([H])[H])C([H])([H])C([H])([H])[C@@]1([H])C(C([H])([H])[H])(C([H])([H])[H])C2([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]N(C(=O)C([H])([H])C([H])([H])C([H])([H])C(\[H])=C(\[H])C([H])([H])C(\[H])=C(\[H])C([H])([H])C(\[H])=C(\[H])C([H])([H])C(\[H])=C(\[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])Cl
[H]C1=C([H])C([H])=C2C3=NN(C(=O)C3=C([H])N(C2=C1[H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(C(=O)C1=C([H])N(C2=C([H])C([H])=C([H])C([H])=C2C1=O)C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(C(=O)C1=C([H])N(C2=NC(OC([H])([H])[H])=C([H])C([H])=C2C1=O)C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N([H])C1=C([H])C([H])=C2C(=O)C([H])=C(N(C2=N1)C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C(=O)N([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(C(=O)C1=C([H])N(C2=NC(=C([H])C([H])=C2C1=O)N(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1C([H])=C2C(=O)N(N=C2C2=C([H])C([H])=C(Cl)C([H])=C12)C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])N1N=C2C(=C([H])N(C3=C([H])C([H])=C([H])C([H])=C23)C([H])([H])C([H])([H])N2C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])C1=O
[H]N(C(=O)C1=C([H])N(C2=C([H])C([H])=C([H])C([H])=C2C1=O)C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(C(=O)C1=C([H])N(C2=C([H])C(OC([H])([H])[H])=C([H])C([H])=C2C1=O)C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1C([H])=C2C(=O)N(N=C2C2=C([H])C([H])=C([H])C([H])=C12)C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(C(=O)C1=C([H])N(C2=C([H])C(OC([H])([H])[H])=C([H])C([H])=C2C1=O)C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]C1=C2N(C3=C(C2=C([H])C(=C1[H])C(=O)N1C([H])([H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])C1([H])[H])C([H])([H])N(C3([H])[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])S(=O)(=O)C1([H])C([H])([H])C1([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)N1C2=C([H])C([H])=C(C([H])=C2C2=C1C([H])([H])N(C2([H])[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C(=O)N1C([H])([H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])C1([H])[H]
[H]C1=C2N(C3=C(C2=C([H])C(=C1[H])C(=O)N1C([H])([H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])C1([H])[H])C([H])([H])N(C3([H])[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])S(=O)(=O)C([H])(C([H])([H])[H])C([H])([H])[H]
[H]C([H])=C([H])C([H])([H])N1C([H])([H])C2=C(C3=C([H])C(=C([H])C([H])=C3N2S(=O)(=O)C([H])([H])C([H])([H])[H])C(=O)N2C([H])([H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])C2([H])[H])C1([H])[H]
[H]N(C(=O)C1=C([H])C(=C(C([H])=C1[H])C([H])([H])[H])S(=O)(=O)N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C([H])C([H])=C1Cl
[H]C1=C2N(C3=C(C2=C([H])C(=C1[H])C(=O)N1C([H])([H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])C1([H])[H])C([H])([H])N(C3([H])[H])[C@@]1([H])OC([H])([H])C([H])([H])C([H])([H])C1([H])[H])S(=O)(=O)C([H])([H])C([H])([H])[H]
[H]C1=C2N(C(=O)C([H])([H])[H])C3=C(C2=C([H])C(=C1[H])C(=O)N1C([H])([H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])C1([H])[H])C([H])([H])N(C3([H])[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]C1=C2N(C3=C(C2=C([H])C(=C1[H])C(=O)N1C([H])([H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])C1([H])[H])C([H])([H])N(C([H])([H])C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C3([H])[H])S(=O)(=O)C([H])([H])C([H])([H])[H]
[H]C1=C2N(C3=C(C2=C([H])C(=C1[H])C(=O)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C([H])([H])N(C3([H])[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])S(=O)(=O)C([H])([H])C([H])([H])[H]
[H]C1=C2N(C3=C(C2=C([H])C(=C1[H])C(=O)N1C([H])([H])C([H])([H])C([H])(OC([H])([H])[H])C([H])([H])C1([H])[H])C([H])([H])N(C3([H])[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])S(=O)(=O)C([H])([H])C([H])([H])[H]
[H]C1=C2N(C3=C(C2=C([H])C(=C1[H])C(=O)N1C([H])([H])C([H])([H])C([H])(F)C([H])([H])C1([H])[H])C([H])([H])N(C3([H])[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])S(=O)(=O)C([H])([H])C([H])([H])[H]
[H]C([H])=C([H])C([H])([H])N1C2=C([H])C([H])=C(C([H])=C2C2=C1C([H])([H])N(C2([H])[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C(=O)N1C([H])([H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])C1([H])[H]
[H]C1=C2N(C3=C(C2=C([H])C(=C1[H])C(=O)N1C([H])([H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])C1([H])[H])C([H])([H])N(C3([H])[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])S(=O)(=O)C([H])([H])[H]
[H]C1=C2N(C3=C(C2=C([H])C(=C1[H])C(=O)N(C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])N(C3([H])[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])S(=O)(=O)C([H])([H])C([H])([H])[H]
[H]C1=C2N(C3=C(C2=C([H])C(=C1[H])C(=O)N1C([H])([H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])C1([H])[H])C([H])([H])N(C3([H])[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])[H]
[H]C1=C2N(C3=C(C2=C([H])C(=C1[H])C(=O)N1C([H])([H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])C1([H])[H])C([H])([H])N(C3([H])[H])C1([H])C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])S(=O)(=O)C([H])([H])C([H])([H])[H]
[H]N(C(=O)C1=C([H])C(=C(C([H])=C1[H])C([H])(C([H])([H])[H])C([H])([H])[H])S(=O)(=O)N1C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(C(=O)C1=C([H])C(=C(C([H])=C1[H])C([H])([H])[H])S(=O)(=O)N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C1=NC([H])=C([H])C2=C([H])C([H])=C([H])C([H])=C12
[H]C1=C([H])C(=C(C([H])=C1C(=O)N(C([H])([H])[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])S(=O)(=O)N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])[H]
[H]N(C(=O)[C@]12C([H])([H])[C@@]3([H])C([H])([H])[C@]([H])(C([H])([H])[C@]([H])(C3([H])[H])C1([H])[H])C2([H])[H])C1=C([H])N(C2=C([H])C([H])=C([H])C([H])=C2C1=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]C1=C([H])C([H])=C2C(=O)C(=C([H])N(C2=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C(=O)C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]N(C(=O)C1=C(N(C2=C([H])C([H])=C([H])C([H])=C2C1=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H])[C@]12C([H])([H])[C@@]3([H])C([H])([H])[C@]([H])(C([H])([H])[C@]([H])(C3([H])[H])C1([H])[H])C2([H])[H]
[H]N(C(=O)C1=C([H])N(C2=C([H])C([H])=C([H])C([H])=C2C1=O)C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])[C@]12C([H])([H])[C@]3([H])C([H])([H])[C@](C([H])([H])[H])(C1([H])[H])C([H])([H])[C@@](C([H])([H])[H])(C3([H])[H])C2([H])[H]
[H]N(C(=O)C1=C([H])N(C2=C([H])C([H])=C(Cl)C([H])=C2C1=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])[C@@]([H])(C([H])([H])[H])[C@]12C([H])([H])[C@@]3([H])C([H])([H])[C@]([H])(C([H])([H])[C@]([H])(C3([H])[H])C1([H])[H])C2([H])[H]
[H]C1=C([H])C([H])=C2C(=C1[H])N(C([H])=C(C(=O)C1=C([H])C([H])=C3C(=C1[H])C([H])([H])OC3([H])[H])C2=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]N(C(=O)C1=C([H])N(C2=C([H])C([H])=C([H])N=C2C1=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])[C@]12C([H])([H])[C@]3([H])C([H])([H])[C@](C([H])([H])[H])(C1([H])[H])C([H])([H])[C@@](C([H])([H])[H])(C3([H])[H])C2([H])[H]
[H]N(C(=O)C1=C([H])N(C2=NC([H])=C([H])C([H])=C2C1=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])[C@]12C([H])([H])[C@]3([H])C([H])([H])[C@](C([H])([H])[H])(C1([H])[H])C([H])([H])[C@@](C([H])([H])[H])(C3([H])[H])C2([H])[H]
[H]N(C(=O)C1=C([H])N(C2=C([H])C([H])=C([H])C([H])=C2C1=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])[C@]12C([H])([H])[C@@]3([H])C([H])([H])[C@]([H])(C([H])([H])[C@]([H])(C3([H])[H])C1([H])[H])C2([H])[H]
[H]N(C(=O)C1=C([H])N(C2=C([H])C([H])=NC([H])=C2C1=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])[C@]12C([H])([H])[C@]3([H])C([H])([H])[C@](C([H])([H])[H])(C1([H])[H])C([H])([H])[C@@](C([H])([H])[H])(C3([H])[H])C2([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C(=O)C1=C([H])N(C2=C([H])C([H])=C([H])C([H])=C2C1=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]N(C(=O)C1=C([H])N(C2=C(Cl)C([H])=C([H])C([H])=C2C1=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])[C@]12C([H])([H])[C@]3([H])C([H])([H])[C@](C([H])([H])[H])(C1([H])[H])C([H])([H])[C@@](C([H])([H])[H])(C3([H])[H])C2([H])[H]
[H]C1=C([H])C([H])=C2C(C([H])=C([H])C([H])=C2C(=O)C2=C([H])N(C3=C([H])C([H])=C([H])C([H])=C3C2=O)C([H])([H])C2=C([H])C([H])=C(Br)C([H])=C2[H])=C1[H]
[H]N(C(=O)C1=C([H])N(C2=C([H])C([H])=C(Cl)C([H])=C2C1=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])[C@]12C([H])([H])[C@]3([H])C([H])([H])[C@](C([H])([H])[H])(C1([H])[H])C([H])([H])[C@@](C([H])([H])[H])(C3([H])[H])C2([H])[H]
[H]N(C(=O)C1=C([H])N(C2=C([H])C([H])=C([H])C([H])=C2C1=O)C([H])([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])[C@]12C([H])([H])[C@]3([H])C([H])([H])[C@](C([H])([H])[H])(C1([H])[H])C([H])([H])[C@@](C([H])([H])[H])(C3([H])[H])C2([H])[H]
[H]N(C(=O)C1=C([H])N(C2=C([H])C([H])=C([H])C([H])=C2C1=O)C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])[C@]12C([H])([H])[C@]3([H])C([H])([H])[C@](C([H])([H])[H])(C1([H])[H])C([H])([H])[C@@](C([H])([H])[H])(C3([H])[H])C2([H])[H]
[H]N1C2=C([H])C([H])=C(C([H])=C2C2=C1C([H])([H])N(C2([H])[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C(=O)N1C([H])([H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])C1([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1C2=C([H])C([H])=C(C([H])=C2C2=C1C([H])([H])N(C2([H])[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C(=O)N1C([H])([H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])C1([H])[H]
[H]C1=C2N(C3=C(C2=C([H])C(=C1[H])C(=O)N1C([H])([H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])C1([H])[H])C([H])([H])N(C3([H])[H])[C@@]1([H])C([H])([H])OC([H])([H])C1([H])[H])S(=O)(=O)C([H])([H])C([H])([H])[H]
[H]N(C(=O)C(OC1=C([H])C([H])=C(C([H])=N1)C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])[C@@]([H])(C([H])([H])[H])[C@]([H])(C1=C([H])C([H])=C([H])C(C#N)=C1[H])C([H])([H])C1=C([H])C([H])=C(OC([H])([H])C([H])([H])F)C([H])=C1[H]
[H]C1=C([H])C([H])=C2C(C([H])=C([H])C([H])=C2C(=O)C2=C([H])N(C3=C([H])C([H])=C([H])C([H])=C3C2=O)C([H])([H])C2=C([H])C([H])=C(F)C([H])=C2[H])=C1[H]
[H]C1=C([H])C([H])=C2C(C([H])=C([H])C([H])=C2C(=O)C2=C([H])N(C3=C([H])C([H])=C([H])C([H])=C3C2=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])=C1[H]
[H]C1=C([H])C([H])=C2C(C([H])=C([H])C([H])=C2C(=O)C2=C([H])N(C3=C([H])C([H])=C([H])C([H])=C3C2=O)C([H])([H])C2=C([H])C([H])=C(Cl)C([H])=C2[H])=C1[H]
[H]N(C(=O)C1=NN(C2=C([H])C([H])=C([H])C([H])=C2C1=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])[C@]12C([H])([H])[C@]3([H])C([H])([H])[C@](C([H])([H])[H])(C1([H])[H])C([H])([H])[C@@](C([H])([H])[H])(C3([H])[H])C2([H])[H]
[H]C1=C2N(C(=NC2=C([H])C(=C1[H])C(=O)N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(OC([H])([H])C(F)(F)F)C([H])=C1[H])C([H])([H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]C1=C2N(C(=NC2=C([H])C(=C1[H])C(=O)N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(OC(F)(F)F)C([H])=C1[H])C([H])([H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]C1=C2N(C(=NC2=C([H])C(=C1[H])C(=O)N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(OC2([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]C1=C2N(C(=NC2=C([H])C(=C1[H])N(C(=O)N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(OC([H])([H])C([H])([H])[H])C([H])=C1[H])C([H])([H])C1([H])C([H])([H])C1([H])[H]
[H]N(C(=O)N(C1=C([H])C([H])=C2N(C(=NC2=C1[H])C([H])([H])C1=C([H])C([H])=C(OC([H])([H])C([H])([H])[H])C([H])=C1[H])C([H])([H])C1([H])C([H])([H])C1([H])[H])C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]C1=C2N(C(=NC2=C([H])C(=C1[H])N(C(=O)N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(OC([H])([H])C([H])([H])[H])C([H])=C1[H])C([H])([H])C1([H])C([H])([H])C1([H])[H]
[H]C1=C2N(C(=NC2=C([H])C(=C1[H])N(C(=O)N(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(OC([H])([H])C([H])([H])[H])C([H])=C1[H])C([H])([H])C1([H])C([H])([H])C1([H])[H]
[H]C1=C([H])C([H])=C(S1)C(=O)N(C1=C([H])C([H])=C2N(C(=NC2=C1[H])C([H])([H])C1=C([H])C([H])=C(OC([H])([H])C([H])([H])[H])C([H])=C1[H])C([H])([H])C1([H])C([H])([H])C1([H])[H])C([H])([H])[H]
[H]C1=C2N(C(=NC2=C([H])C(=C1[H])N(C(=O)C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(OC([H])([H])C([H])([H])[H])C([H])=C1[H])C([H])([H])C1([H])C([H])([H])C1([H])[H]
[H]C1=C2N(C(=NC2=C([H])C(=C1[H])C(=O)N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(OC([H])([H])C([H])([H])[H])C([H])=C1[H])C([H])([H])C1([H])C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]C1=C([H])C([H])=C(O1)C([H])([H])N1C(=NC2=C([H])C(=C([H])C([H])=C12)C(=O)N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(OC([H])([H])C([H])([H])[H])C([H])=C1[H]
[H]C1=C2N(C(=NC2=C([H])C(=C1[H])C(=O)N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(OC([H])([H])C([H])([H])[H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=[N+]([O-])C([H])=C1[H]
[H]C1=NC([H])=C([H])C(=C1[H])C([H])([H])N1C2=C([H])C([H])=C(C([H])=C2N=C1C([H])([H])C1=C([H])C([H])=C(OC([H])([H])C([H])([H])[H])C([H])=C1[H])C(=O)N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H]
[H]C1=NC(=C([H])C([H])=C1[H])C([H])([H])N1C2=C([H])C([H])=C(C([H])=C2N=C1C([H])([H])C1=C([H])C([H])=C(OC([H])([H])C([H])([H])[H])C([H])=C1[H])C(=O)N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H]
[H]N(N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C(=O)C1=NN(C2=C1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1=C2C([H])=C([H])C(Cl)=C1[H])C1=C([H])C([H])=C(Cl)C([H])=C1Cl
[H]N(N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C(=O)C1=NN(C(=C1C([H])([H])[H])C1=C(C([H])=C(Cl)C([H])=C1C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C(Cl)C([H])=C1Cl
[H]N(N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C(=O)C1=NN(C(=C1C([H])([H])[H])C1=C(C([H])=C(Cl)C([H])=C1[H])C([H])([H])[H])C1=C(Cl)C([H])=C(Cl)C([H])=C1Cl
[H]N(N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C(=O)C1=NN(C(=C1C([H])([H])[H])C1=C(C([H])=C(Cl)C([H])=C1[H])C([H])([H])[H])C1=C([H])C([H])=C(Cl)C([H])=C1Cl
[H]N(N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C(=O)C1=NN(C(=C1C([H])([H])[H])C1=C(Cl)C([H])=C(Cl)C([H])=C1[H])C1=C(Cl)C([H])=C(Cl)C([H])=C1Cl
[H]N(C(=O)N1C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])[C@@]([H])(C1=C([H])C([H])=C(Cl)C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1Cl)C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]N(N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C(=O)C1=NN(C2=C1C([H])([H])C([H])([H])C1=C2C([H])=C([H])C(Cl)=C1[H])C1=C([H])C([H])=C(Cl)C([H])=C1Cl
[H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1C2=C([H])C([H])=C(C([H])=C2N=C1C([H])([H])C1=C([H])C([H])=C(OC([H])([H])C([H])([H])[H])C([H])=C1[H])C(=O)N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H]
[H]C1=C2N(C(=NC2=C([H])C(=C1[H])C(=O)N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(OC([H])([H])C([H])([H])[H])C([H])=C1[H])C([H])([H])[C@]12C([H])([H])[C@@]3([H])C([H])([H])[C@]([H])(C([H])([H])[C@]([H])(C3([H])[H])C1([H])[H])C2([H])[H]
[H]C1=C2N(C(=NC2=C([H])C(=C1[H])C(=O)N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(OC([H])([H])C([H])([H])[H])C([H])=C1[H])C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]C1=C2N(C(=NC2=C([H])C(=C1[H])C(=O)N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(OC([H])([H])C([H])([H])[H])C([H])=C1[H])C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]C1=C2N(C(=NC2=C([H])C(=C1[H])C(=O)N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(OC([H])([H])C([H])([H])[H])C([H])=C1[H])C([H])([H])C1([H])C([H])([H])C([H])([H])C1([H])[H]
[H]C1=C2N(C(=NC2=C([H])C(=C1[H])C(=O)N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(OC([H])([H])C([H])([H])[H])C([H])=C1[H])C([H])([H])C1([H])C([H])([H])C1([H])[H]
[H]C1=C2N(C(=NC2=C([H])C(=C1[H])C(=O)N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(OC2([H])C([H])([H])C([H])([H])C2([H])[H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]C1=C2N(C(=NC2=C([H])C(=C1[H])C(=O)N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]OC1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C1=NC2=C([H])C(=C([H])C([H])=C2N1C([H])([H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C(=O)N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H]
[H]O[C@@]([H])(C1=NC2=C([H])C(=C([H])C([H])=C2N1C([H])([H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C(=O)N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H])C1=C([H])C([H])=C(OC([H])([H])C([H])([H])[H])C([H])=C1[H]
[H]C1=C2N(C(=NC2=C([H])C(=C1[H])C(=O)N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H])C(=O)C1=C([H])C([H])=C(OC([H])([H])C([H])([H])[H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]C1=C2N(C(=NC2=C([H])C(=C1[H])C(=O)N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(OC([H])([H])C([H])([H])[H])C([H])=N1)C([H])([H])C1([H])C([H])([H])C1([H])[H]
[H]C1=C2N(C(=NC2=C([H])C(=C1[H])C(=O)N(C([H])([H])C(F)(F)F)C([H])([H])C(F)(F)F)C([H])([H])C1=C([H])C([H])=C(OC([H])([H])C([H])([H])[H])C([H])=C1[H])C([H])([H])C1([H])C([H])([H])C1([H])[H]
[H]C1=C2N(C(=NC2=C([H])C(=C1[H])C(=O)N(C([H])([H])[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C(OC([H])([H])C([H])([H])[H])C([H])=C1[H])C([H])([H])C1([H])C([H])([H])C1([H])[H]
[H]C1=C2N(C(=NC2=C([H])C(=C1[H])C(=O)N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C(OC([H])([H])C([H])([H])[H])C([H])=C1[H])C([H])([H])C1([H])C([H])([H])C1([H])[H]
[H]C1=C2N(C(=NC2=C([H])C(=C1[H])C(=O)N1C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C(OC([H])([H])C([H])([H])[H])C([H])=C1[H])C([H])([H])C1([H])C([H])([H])C1([H])[H]
[H]C1=C2N(C(=NC2=C([H])C(=C1[H])C(=O)N(C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(OC([H])([H])C([H])([H])[H])C([H])=C1[H])C([H])([H])C1([H])C([H])([H])C1([H])[H]
[H]C1=C2N(C(=NC2=C([H])C(=C1[H])C(=O)N(C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(OC([H])([H])C([H])([H])[H])C([H])=C1[H])C([H])([H])C1([H])C([H])([H])C1([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C2N(C(=NC2=C1[H])C([H])([H])C1=C([H])C([H])=C(OC([H])([H])C([H])([H])[H])C([H])=C1[H])C([H])([H])C1([H])C([H])([H])C1([H])[H])C([H])([H])C([H])([H])[H]
[H]C1=C([H])C([H])=C(OC2=C([H])C([H])=C(C([H])=C2[H])C([H])([H])C2=NC3=C([H])C(=C([H])C([H])=C3N2C([H])([H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C(=O)N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H])C([H])=C1[H]
[H]OC1=C([H])C(=C([H])C2=C1[C@]1([H])C([H])([H])C(=C([H])C([H])([H])[C@@]1([H])C(O2)(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C(C1=C([H])C([H])=C(C([H])=C1[H])C(=O)N([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]OC1=C([H])C(=C([H])C2=C1[C@]1([H])C([H])([H])C(=C([H])C([H])([H])[C@@]1([H])C(O2)(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C(C1=C([H])C(C#N)=C([H])C([H])=C1[H])(C([H])([H])[H])C([H])([H])[H]
[H]OC1=C([H])C(=C([H])C2=C1[C@]1([H])C([H])([H])C(=C([H])C([H])([H])[C@@]1([H])C(O2)(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C(C1=C([H])C([H])=C(C#N)C([H])=C1[H])(C([H])([H])[H])C([H])([H])[H]
[H]OC1=C([H])C(=C([H])C2=C1[C@]1([H])C([H])([H])C(=C([H])C([H])([H])[C@@]1([H])C(O2)(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C(C1=C([H])C([H])=C([H])S1)(C([H])([H])[H])C([H])([H])[H]
[H]OC1=C([H])C(=C([H])C2=C1[C@]1([H])C([H])([H])C(=C([H])C([H])([H])[C@@]1([H])C(O2)(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C(C1=C([H])C(Br)=C([H])C([H])=C1[H])(C([H])([H])[H])C([H])([H])[H]
[H]OC1=C([H])C(=C([H])C2=C1[C@]1([H])C([H])([H])C(=C([H])C([H])([H])[C@@]1([H])C(O2)(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C(C1=C([H])C([H])=C(Br)C([H])=C1[H])(C([H])([H])[H])C([H])([H])[H]
[H]OC1=C([H])C(=C([H])C2=C1[C@]1([H])C([H])([H])C(=C([H])C([H])([H])[C@@]1([H])C(O2)(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C(C1=C([H])C(Cl)=C([H])C([H])=C1[H])(C([H])([H])[H])C([H])([H])[H]
[H]OC1=C([H])C(=C([H])C2=C1[C@]1([H])C([H])([H])C(=C([H])C([H])([H])[C@@]1([H])C(O2)(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C(C1=C([H])C([H])=C(Cl)C([H])=C1[H])(C([H])([H])[H])C([H])([H])[H]
[H]OC1=C([H])C(=C([H])C2=C1[C@]1([H])C([H])([H])C(=C([H])C([H])([H])[C@@]1([H])C(O2)(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C(C1=C([H])C(F)=C([H])C([H])=C1[H])(C([H])([H])[H])C([H])([H])[H]
[H]OC1=C([H])C(=C([H])C2=C1[C@]1([H])C([H])([H])C(=C([H])C([H])([H])[C@@]1([H])C(O2)(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C(C1=C([H])C([H])=C(F)C([H])=C1[H])(C([H])([H])[H])C([H])([H])[H]
[H]OC1=C([H])C(=C([H])C2=C1[C@]1([H])C([H])([H])C(=C([H])C([H])([H])[C@@]1([H])C(O2)(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C(C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]OC1=C([H])C(=C([H])C2=C1[C@]1([H])C([H])([H])C(=C([H])C([H])([H])[C@@]1([H])C(O2)(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C(C1=C([H])C(=C([H])C(=C1[H])C([H])([H])[H])C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]OC1=C([H])C(=C([H])C2=C1[C@]1([H])C([H])([H])C(=C([H])C([H])([H])[C@@]1([H])C(O2)(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C(C1=C(C([H])=C([H])C([H])=C1[H])C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]OC1=C([H])C(=C([H])C2=C1[C@]1([H])C([H])([H])C(=C([H])C([H])([H])[C@@]1([H])C(O2)(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C(C1=C([H])C(=C([H])C([H])=C1[H])C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]C1=C2N(C(=NC2=C([H])C(=C1[H])C(=O)N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(OC([H])([H])C([H])([H])[H])C([H])=C1[H])C([H])([H])[C@@]1([H])N(C([H])([H])[H])C([H])([H])C([H])([H])C1([H])[H]
[H]C1=C2N(C(=NC2=C([H])C(=C1[H])C(=O)N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(OC([H])([H])C([H])([H])[H])C([H])=C1[H])C([H])([H])[C@]1([H])N(C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@]1([H])C([H])([H])N1C2=C([H])C([H])=C(C([H])=C2N=C1C([H])([H])C1=C([H])C([H])=C(OC([H])([H])C([H])([H])[H])C([H])=C1[H])C(=O)N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H]
[H]N1C([H])([H])C([H])([H])C([H])(C([H])([H])N2C3=C([H])C([H])=C(C([H])=C3N=C2C([H])([H])C2=C([H])C([H])=C(OC([H])([H])C([H])([H])[H])C([H])=C2[H])C(=O)N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]C1=C2N(C(=NC2=C([H])C(=C1[H])C(=O)N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(OC([H])([H])C([H])([H])[H])C([H])=C1[H])C([H])([H])[C@]1([H])OC([H])([H])C([H])([H])C1([H])[H]
[H]N(C(=O)N1C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])[C@@]([H])(C1=C([H])C([H])=C(Cl)C([H])=C1[H])C1=C([H])C([H])=C(Cl)C([H])=C1Cl)C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(C(=O)N1C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])[C@@]([H])(C1=C([H])C([H])=C(Br)C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1Cl)C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C1=C([H])C([H])=C2N(C(=NC2=C1[H])C([H])([H])C1=C([H])C([H])=C(OC([H])([H])C([H])([H])[H])C([H])=C1[H])C([H])([H])C1([H])C([H])([H])C1([H])[H])C([H])([H])[H]
[H]C1=C2N(C(=NC2=C([H])C(=C1[H])N(C(=O)C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(OC([H])([H])C([H])([H])[H])C([H])=C1[H])C([H])([H])C1([H])C([H])([H])C1([H])[H]
[H]C1=C2N(C(=NC2=C([H])C(=C1[H])C(=O)N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(OC([H])([H])C([H])([H])[H])C([H])=C1[H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H]
[H]C1=C2N(C(=NC2=C([H])C(=C1[H])C(=O)N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(OC([H])([H])C([H])([H])[H])N=C1[H])C([H])([H])C1([H])C([H])([H])C1([H])[H]
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[H]N(C(=O)C([H])([H])C([H])([H])C1=NC(=NO1)C1=C(Cl)C([H])=C(F)C([H])=C1[H])C1=NOC(=C1[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)C([H])([H])C([H])([H])C1=NC(=NO1)C1=C(Cl)C([H])=C(F)C([H])=C1[H])C1=C([H])N=C(N=C1[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)C([H])([H])C([H])([H])C1=NC(=NO1)C1=C(Cl)C([H])=C(F)C([H])=C1[H])C1=C([H])C(C#N)=C(OC([H])([H])C(F)(F)F)N=C1[H]
[H]N(C(=O)C([H])([H])C([H])([H])C1=NC(=NO1)C1=C(Cl)C([H])=C(F)C([H])=C1[H])C1=C([H])C([H])=C(N=C1[H])C(F)(F)F
[H]N(C(=O)C([H])([H])C([H])([H])C1=NC(=NO1)C1=C(Cl)C([H])=C(F)C([H])=C1[H])C1=C([H])C([H])=C(C(Cl)=C1[H])C(F)(F)F
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[H]N(N1C([H])([H])[C@@]2([H])C([H])([H])C([H])([H])C([H])([H])[C@@]2([H])C1([H])[H])C(=O)C1=NN(C(C2=C([H])C([H])=C(S2)C#CC([H])([H])C([H])([H])[H])=C1C([H])([H])[H])C1=C([H])C([H])=C(Cl)C([H])=C1Cl
[H]N(N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C(=O)C1=NN(C(C2=C([H])C([H])=C(S2)C#CC([H])([H])C([H])([H])[H])=C1C([H])([H])[H])C1=C([H])C([H])=C(Cl)C([H])=C1Cl
[H]N(N1C([H])([H])[C@@]2([H])C([H])([H])C([H])([H])C([H])([H])[C@@]2([H])C1([H])[H])C(=O)C1=NN(C(C2=C([H])C([H])=C(S2)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])=C1C([H])([H])[H])C1=C([H])C([H])=C(Cl)C([H])=C1Cl
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[H]N(N1C([H])([H])[C@@]2([H])C([H])([H])C([H])([H])C([H])([H])[C@@]2([H])C1([H])[H])C(=O)C1=NN(C(C2=C([H])C([H])=C(S2)C(\[H])=C(/[H])C([H])([H])C([H])([H])C([H])([H])[H])=C1C([H])([H])[H])C1=C([H])C([H])=C(Cl)C([H])=C1Cl
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[H]N(C(=O)N1C(=O)N(C2=C([H])C([H])=C([H])C([H])=C12)C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])[C@]([H])(C1=C([H])C([H])=C(F)C([H])=C1[H])C([H])([H])[H]
[H]C1=C([H])C([H])=C2N(C(=O)N(C(=O)N(C([H])([H])[H])C3([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C3([H])[H])C2=C1[H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]N(C(=O)N1C(=O)N(C2=C([H])C([H])=C([H])C([H])=C12)C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(C(=O)N1C(=O)N(C2=C([H])C([H])=C([H])C([H])=C2C1([H])[H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])[C@@]1([H])C2=C(C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C1([H])[H]
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[H]N(C(=O)N1C(=O)N(C2=C([H])C([H])=C([H])C([H])=C12)C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])[C@@]1([H])C2=C(C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C1([H])[H]
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[H]N(C(=O)C([H])([H])C([H])([H])C1=NC(=NO1)C1=C(Cl)C([H])=C(F)C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C(F)(F)F
[H]N(C(=O)C([H])([H])C([H])([H])C1=NC(=NO1)C1=C(Cl)C([H])=C(F)C([H])=C1[H])C1=NN=C(S1)N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(C(=O)C([H])([H])C([H])([H])C1=NC(=NO1)C1=C(Cl)C([H])=C(F)C([H])=C1[H])C1=NC2=C(S1)C([H])=C(OC(F)(F)F)C([H])=C2[H]
[H]N(C(=O)C([H])([H])C([H])([H])C1=NC(=NO1)C1=C(Cl)C([H])=C(F)C([H])=C1[H])C1=C([H])N=C2N=C([H])C(Cl)=C([H])C2=C1[H]
[H]N(C(=O)C([H])([H])C([H])([H])C1=NC(=NO1)C1=C(Cl)C([H])=C(F)C([H])=C1[H])C1=C([H])N=C2C([H])=C([H])C(Cl)=C([H])C2=C1[H]
[H]N(C(=O)C([H])([H])C([H])([H])C1=NC(=NO1)C1([H])C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C1=C([H])C2=C(C([H])=C1[H])N(C1=C2C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])[H]
[H]N(C(=O)C([H])([H])C([H])([H])C1=NC(=NO1)C1=C(C#N)C([H])=NC([H])=C1[H])C1=C([H])C2=C(C([H])=C1[H])N(C1=C2C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])[H]
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[H]N(N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C(=O)C1=NN(C(C2=C([H])C([H])=C(S2)C#CC([H])([H])C([H])([H])C([H])([H])[H])=C1C([H])([H])C([H])([H])[H])C1=C([H])C([H])=C(Cl)C([H])=C1Cl
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[H]N(N1C([H])([H])[C@@]2([H])C([H])([H])C([H])([H])C([H])([H])[C@@]2([H])C1([H])[H])C(=O)C1=NN(C(C2=C([H])C([H])=C(S2)C#CC([H])([H])C([H])([H])C([H])([H])[H])=C1C([H])([H])[H])C1=C([H])C([H])=C(Cl)C([H])=C1Cl
[H]N(N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C(=O)C1=NN(C(C2=C([H])C([H])=C(Cl)S2)=C1C([H])([H])[H])C1=C([H])C([H])=C(Cl)C([H])=C1Cl
[H]N(N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C(=O)C1=NN(C(C2=C([H])C([H])=C(Br)S2)=C1C([H])([H])[H])C1=C([H])C([H])=C(Cl)C([H])=C1Cl
[H]N(N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C(=O)C1=NN(C(C2=C([H])C([H])=C(S2)C#CC2([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])=C1C([H])([H])[H])C1=C([H])C([H])=C(Cl)C([H])=C1Cl
[H]N(N1C([H])([H])[C@@]2([H])C([H])([H])C([H])([H])C([H])([H])[C@@]2([H])C1([H])[H])C(=O)C1=NN(C(C2=C([H])C([H])=C(S2)C#CC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])=C1C([H])([H])[H])C1=C([H])C([H])=C(Cl)C([H])=C1Cl
[H]N(N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C(=O)C1=NN(C(C2=C([H])C([H])=C(S2)C#CC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])=C1C([H])([H])[H])C1=C([H])C([H])=C(Cl)C([H])=C1Cl
[H]N(C(=O)C1=NN(C(C2=C([H])C([H])=C(S2)C#CC([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])=C1C([H])([H])[H])C1=C([H])C([H])=C(Cl)C([H])=C1Cl)C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(C(=O)C1=NN(C(C2=C([H])C([H])=C(S2)C#CC([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])=C1C([H])([H])[H])C1=C([H])C([H])=C(Cl)C([H])=C1Cl)C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]N(N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C(=O)C1=NN(C(C2=C([H])C([H])=C(S2)C#CC([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])=C1C([H])([H])[H])C1=C([H])C([H])=C(Cl)C([H])=C1Cl
[H]N(N1C([H])([H])[C@@]2([H])C([H])([H])C([H])([H])C([H])([H])[C@@]2([H])C1([H])[H])C(=O)C1=NN(C(C2=C([H])C([H])=C(S2)C#CC([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])=C1C([H])([H])[H])C1=C([H])C([H])=C(Cl)C([H])=C1Cl
[H]N(N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C(=O)C1=NN(C(C2=C([H])C([H])=C(S2)C#CC([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])=C1C([H])([H])[H])C1=C([H])C([H])=C(Cl)C([H])=C1Cl
[H]C1=C([H])C2=NC([H])=C(C([H])=C2C([H])=C1[H])N1C([H])([H])C([H])([H])[C@@]([H])(C([H])([H])C2=NC(=NO2)C2=C([H])C([H])=C(F)C([H])=C2Cl)C1([H])[H]
[H]N(C1=C([H])N=C2C([H])=C([H])C([H])=C([H])C2=C1[H])C([H])([H])[C@@]1([H])C([H])([H])[C@]1([H])C1=NC(=NO1)C1=C([H])C([H])=C(F)C([H])=C1Cl
[H]N(C1=C([H])N=C2C([H])=C([H])C([H])=C([H])C2=C1[H])[C@]1([H])C([H])([H])C([H])([H])[C@]([H])(C2=NC(=NO2)C2=C([H])C([H])=C(F)C([H])=C2Cl)C1([H])[H]
[H]N(C1=C([H])N=C2C([H])=C([H])C([H])=C([H])C2=C1[H])[C@]1([H])C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C1=NC(=NO1)C1=C([H])C([H])=C(F)C([H])=C1Cl
[H]N(C1=C([H])N=C2C([H])=C([H])C([H])=C([H])C2=C1[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C([H])([H])C1=NC(=NO1)C1=C([H])C([H])=C(F)C([H])=C1Cl
[H]N(C1=C([H])N=C2C([H])=C([H])C([H])=C([H])C2=C1[H])[C@@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])C1=NC(=NO1)C1=C([H])C([H])=C(F)C([H])=C1Cl
[H]N(C1=C([H])N=C2C([H])=C([H])C([H])=C([H])C2=C1[H])C([H])([H])C([H])([H])C([H])([H])C1=NC(=NO1)C1=C([H])C([H])=C(F)C([H])=C1Cl
[H]N(C(=O)C1=C([H])N=C2C([H])=C([H])C([H])=C([H])C2=C1[H])C([H])([H])C([H])([H])C1=NC(=NO1)C1=C([H])C([H])=C(F)C([H])=C1Cl
[H]N(C(=O)C1=C([H])N(C2=C([H])C(OC([H])([H])C([H])([H])[H])=C([H])C([H])=C2C1=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])[C@@]([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H]
[H]N(C(=O)C1=C([H])N(C2=C([H])C(=C([H])C([H])=C2C1=O)N1C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])[C@@]([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H]
[H]N(C(=O)C1=C([H])N(C2=C([H])C(F)=C([H])C([H])=C2C1=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])[C@@]([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H]
[H]N(C(=O)C1=C([H])N(C2=C([H])C(F)=C([H])C([H])=C2C1=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])[C@]12C([H])([H])[C@@]3([H])C([H])([H])[C@]([H])(C([H])([H])[C@]([H])(C3([H])[H])C1([H])[H])C2([H])[H]
[H]N(C(=O)C1=C([H])N(C2=C([H])C(N3C([H])=C([H])C([H])=C3[H])=C(F)C([H])=C2C1=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])[C@]12C([H])([H])[C@@]3([H])C([H])([H])[C@]([H])(C([H])([H])[C@]([H])(C3([H])[H])C1([H])[H])C2([H])[H]
[H]C([H])=C([H])C([H])([H])N1C([H])=C(C(=O)N([H])[C@]23C([H])([H])[C@@]4([H])C([H])([H])[C@]([H])(C([H])([H])[C@]([H])(C4([H])[H])C2([H])[H])C3([H])[H])C(=O)C2=C(OC([H])([H])[H])C([H])=C([H])C(OC([H])([H])[H])=C12
[H]N(C(=O)C1=C([H])N(C2=C(OC([H])([H])[H])C([H])=C([H])C(OC([H])([H])[H])=C2C1=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])[C@]12C([H])([H])[C@@]3([H])C([H])([H])[C@]([H])(C([H])([H])[C@]([H])(C3([H])[H])C1([H])[H])C2([H])[H]
[H]N(C(=O)C1=C([H])N(C2=C([H])C([H])=C(SC3=C([H])C([H])=C([H])C([H])=C3[H])C([H])=C2C1=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])[C@]12C([H])([H])[C@@]3([H])C([H])([H])[C@]([H])(C([H])([H])[C@]([H])(C3([H])[H])C1([H])[H])C2([H])[H]
[H]N(C(=O)C1=C([H])N(C2=C([H])C([H])=C(Br)C([H])=C2C1=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])[C@]12C([H])([H])[C@@]3([H])C([H])([H])[C@]([H])(C([H])([H])[C@]([H])(C3([H])[H])C1([H])[H])C2([H])[H]
[H]C([H])=C([H])C([H])([H])C([H])([H])C([H])([H])N1C([H])=C(C(=O)N([H])[C@]23C([H])([H])[C@@]4([H])C([H])([H])[C@]([H])(C([H])([H])[C@]([H])(C4([H])[H])C2([H])[H])C3([H])[H])C(=O)C2=C([H])C(Br)=C([H])C([H])=C12
[H]C([H])=C([H])C([H])([H])C([H])([H])N1C([H])=C(C(=O)N([H])[C@]23C([H])([H])[C@@]4([H])C([H])([H])[C@]([H])(C([H])([H])[C@]([H])(C4([H])[H])C2([H])[H])C3([H])[H])C(=O)C2=C([H])C(Br)=C([H])C([H])=C12
[H]N(C(=O)C1=C([H])N(C2=C([H])C([H])=C(C([H])=C2C1=O)C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])[C@]12C([H])([H])[C@@]3([H])C([H])([H])[C@]([H])(C([H])([H])[C@]([H])(C3([H])[H])C1([H])[H])C2([H])[H]
[H]N(C(=O)C1=C([H])N(C2=C([H])C([H])=C(C([H])=C2C1=O)C(F)(F)F)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])[C@]12C([H])([H])[C@@]3([H])C([H])([H])[C@]([H])(C([H])([H])[C@]([H])(C3([H])[H])C1([H])[H])C2([H])[H]
[H]N(C(=O)C1=C([H])N(C2=C([H])C([H])=C(\C([H])=C(/[H])C3=C([H])C([H])=C(OC([H])([H])[H])C([H])=C3[H])C([H])=C2C1=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])[C@]12C([H])([H])[C@@]3([H])C([H])([H])[C@]([H])(C([H])([H])[C@]([H])(C3([H])[H])C1([H])[H])C2([H])[H]
[H]N(C(=O)C1=C([H])N(C2=C([H])C([H])=C(C([H])=C2C1=O)C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])[C@]12C([H])([H])[C@@]3([H])C([H])([H])[C@]([H])(C([H])([H])[C@]([H])(C3([H])[H])C1([H])[H])C2([H])[H]
[H]N(C(=O)C1=C([H])N(C2=C([H])C(=C([H])C([H])=C2C1=O)[S@](=O)C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])[C@]12C([H])([H])[C@@]3([H])C([H])([H])[C@]([H])(C([H])([H])[C@]([H])(C3([H])[H])C1([H])[H])C2([H])[H]
[H]N(C(=O)C1=C([H])N(C2=C([H])C(=C([H])C([H])=C2C1=O)S(=O)(=O)C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])[C@]12C([H])([H])[C@@]3([H])C([H])([H])[C@]([H])(C([H])([H])[C@]([H])(C3([H])[H])C1([H])[H])C2([H])[H]
[H]N(C(=O)C1=C([H])N(C2=C([H])C(SC3=C([H])C([H])=C([H])C([H])=C3[H])=C([H])C([H])=C2C1=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])[C@]12C([H])([H])[C@@]3([H])C([H])([H])[C@]([H])(C([H])([H])[C@]([H])(C3([H])[H])C1([H])[H])C2([H])[H]
[H]N(C(=O)C1=C([H])N(C2=C(C(Cl)=C([H])C([H])=C2C1=O)C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])[C@]12C([H])([H])[C@@]3([H])C([H])([H])[C@]([H])(C([H])([H])[C@]([H])(C3([H])[H])C1([H])[H])C2([H])[H]
[H]N(C(=O)C1=C([H])N(C2=C([H])C([H])=C(OC3=C([H])C([H])=C(F)C(Cl)=C3[H])C([H])=C2C1=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])[C@]12C([H])([H])[C@@]3([H])C([H])([H])[C@]([H])(C([H])([H])[C@]([H])(C3([H])[H])C1([H])[H])C2([H])[H]
[H]C1=C([H])C2=NC([H])=C(C([H])=C2C([H])=C1[H])N1C([H])([H])C([H])([H])C([H])(C2=NC(=NO2)C2=C([H])C([H])=C(Cl)C([H])=C2Cl)C([H])([H])C1([H])[H]
[H]N(C(=O)C([H])([H])C([H])([H])C1=NC(=NO1)C1=C([H])C([H])=C(F)C([H])=C1Cl)C1=C([H])N=C2C([H])=C([H])C([H])=C([H])C2=C1[H]
[H]N(N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C(=O)C1=NN(C(C2=C([H])C([H])=C(S2)C#CC([H])([H])OC2=C([H])C([H])=C([H])C([H])=C2[H])=C1C([H])([H])[H])C1=C([H])C([H])=C(Cl)C([H])=C1Cl
[H]N(N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C(=O)C1=NN(C(C2=C([H])C([H])=C(S2)C#CC([H])([H])N(C([H])([H])[H])C([H])([H])[H])=C1C([H])([H])[H])C1=C([H])C([H])=C(Cl)C([H])=C1Cl
[H]N(N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C(=O)C1=NN(C(C2=C([H])C([H])=C(S2)C#CC([H])([H])N([H])C([H])(C([H])([H])[H])C([H])([H])[H])=C1C([H])([H])[H])C1=C([H])C([H])=C(Cl)C([H])=C1Cl
[H]N(N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C(=O)C1=NN(C(C2=C([H])C([H])=C(S2)C#CC([H])([H])OC([H])(C([H])([H])[H])C([H])([H])[H])=C1C([H])([H])[H])C1=C([H])C([H])=C(Cl)C([H])=C1Cl
[H]N(N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C(=O)C1=NN(C(C2=C([H])C([H])=C(S2)C#CC([H])([H])OC([H])([H])[H])=C1C([H])([H])[H])C1=C([H])C([H])=C(Cl)C([H])=C1Cl
[H]N(N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C(=O)C1=NN(C(C2=C([H])C([H])=C(S2)C#CC([H])([H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])=C1C([H])([H])[H])C1=C([H])C([H])=C(Cl)C([H])=C1Cl
[H]N(N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C(=O)C1=NN(C(C2=C([H])C([H])=C(S2)C#CC2([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])=C1C([H])([H])[H])C1=C([H])C([H])=C(Cl)C([H])=C1Cl
[H]C1=C(C([H])=C2C(=N1)C([H])([H])C([H])([H])C([H])([H])C2([H])[H])N1C([H])([H])C([H])([H])C([H])(C2=NC(=NO2)C2=C([H])C([H])=C(F)C([H])=C2Cl)C([H])([H])C1([H])[H]
[H]C1=C([H])C2=C([H])C(=C([H])N=C2N1C([H])(C([H])([H])[H])C([H])([H])[H])N1C([H])([H])C([H])([H])C([H])(C2=NC(=NO2)C2=C([H])C([H])=C(F)C([H])=C2Cl)C([H])([H])C1([H])[H]
[H]C1=NC2=C([H])C([H])=C([H])C([H])=C2C(=C1[H])N1C([H])([H])C([H])([H])C([H])(C2=NC(=NO2)C2=C([H])C([H])=C(F)C([H])=C2Cl)C([H])([H])C1([H])[H]
[H]C1=C([H])C(=C([H])C(=C1Cl)C(F)(F)F)N1C([H])([H])C([H])([H])C([H])(C2=NC(=NO2)C2=C([H])C([H])=C(F)C([H])=C2Cl)C([H])([H])C1([H])[H]
[H]C1=C([H])C2=NC([H])=C(C([H])=C2C([H])=C1[H])N1C([H])([H])C([H])([H])C([H])(C2=NC(=NO2)C2=C([H])C([H])=C(F)C([H])=C2Cl)C([H])([H])C1([H])[H]
[H]N(N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C(=O)C1=NN(C2=C1C([H])([H])C([H])([H])C([H])([H])C1=C2C([H])=C([H])C(Cl)=C1[H])C1=C([H])C([H])=C(Cl)C([H])=C1Cl
[H]N(N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C(=O)C1=NN(C(=C1C([H])([H])[H])C1=C(Cl)C([H])=C(Cl)C([H])=C1[H])C1=C([H])C([H])=C(Cl)C([H])=C1Cl
[H]C1=C([H])C2=NC([H])=C(C([H])=C2C([H])=C1[H])N1C([H])([H])C([H])([H])C([H])(C2=NC(=NO2)C2=C([H])C([H])=C(Cl)C([H])=C2[H])C([H])([H])C1([H])[H]
[H]C1=NC([H])=C(Cl)C(=C1[H])C1=NOC(=N1)C1([H])C([H])([H])C([H])([H])N(C2=C([H])N=C3C([H])=C([H])C([H])=C([H])C3=C2[H])C([H])([H])C1([H])[H]
[H]C1=NC([H])=C([H])C(=C1[H])C1=NOC(=N1)C1([H])C([H])([H])C([H])([H])N(C2=C([H])N=C3C([H])=C([H])C([H])=C([H])C3=C2[H])C([H])([H])C1([H])[H]
[H]C1=C(C([H])=C2C([H])=C(OC(F)(F)F)C([H])=C([H])C2=N1)N1C([H])([H])C([H])([H])C([H])(C2=NC(=NO2)C2=C([H])C([H])=C(F)C([H])=C2Cl)C([H])([H])C1([H])[H]
[H]C1=C([H])C2=NC([H])=C(C([H])=C2C([H])=C1[H])N1C([H])([H])C([H])([H])C([H])(C2=NC(=NO2)C2=C([H])C([H])=C([H])C([H])=C2F)C([H])([H])C1([H])[H]
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[H]N([H])C(=O)[C@@]([H])(N([H])C(=O)N1C(=O)N(C2=C([H])C([H])=C([H])C([H])=C12)C([H])([H])C([H])([H])C1([H])C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)N1C(=O)N(C2=C([H])C([H])=C([H])C([H])=C12)C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])[C@]([H])(C1=NC(=NO1)C([H])([H])[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)N1C(=O)N(C2=C([H])C([H])=C([H])C([H])=C12)C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])[C@]([H])(C1=NN(N=N1)C([H])([H])[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)N1C(=O)N(C2=C([H])C([H])=C([H])C([H])=C12)C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])[C@]([H])(C#N)C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]N([H])C(=O)[C@@]([H])(N([H])C(=O)N1C(=O)N(C2=C([H])C([H])=C([H])C([H])=C12)C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N([H])C(=O)[C@@]([H])(N([H])C(=O)N1C(=O)N(C2=C([H])C([H])=C([H])C([H])=C12)C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N([H])C(=O)[C@@]([H])(N([H])C(=O)N1C(=O)N(C2=C([H])C([H])=C([H])C([H])=C12)C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])[C@@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])[H]
[H]N([H])C(=O)[C@@]([H])(N([H])C(=O)N1C(=O)N(C2=C([H])C([H])=C([H])C([H])=C12)C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)[C@@]([H])(N([H])C(=O)N1C(=O)N(C2=C([H])C([H])=C([H])C([H])=C12)C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)N1C(=O)N(C2=C([H])C([H])=C([H])C([H])=C12)C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])[C@]([H])(C(=O)N(C([H])([H])[H])C([H])([H])[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]OC([H])([H])[C@@]([H])(N([H])C(=O)N1C(=O)N(C2=C([H])C([H])=C([H])C([H])=C12)C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]O[C@@]1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@]1([H])N([H])C(=O)N1C(=O)N(C2=C([H])C([H])=C([H])C([H])=C12)C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]C1=C(C([H])=C2C([H])=C(Cl)C([H])=C([H])C2=N1)N1C([H])([H])C([H])([H])C([H])(C2=NC(=NO2)C2=C([H])C([H])=C(F)C([H])=C2Cl)C([H])([H])C1([H])[H]
[H]C1=C([H])C2=C([H])C(=C([H])N=C2C(=C1[H])C(F)(F)F)N1C([H])([H])C([H])([H])C([H])(C2=NC(=NO2)C2=C([H])C([H])=C(F)C([H])=C2Cl)C([H])([H])C1([H])[H]
[H]C1=C(C([H])=C2C(=N1)C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C([H])([H])C2([H])[H])N1C([H])([H])C([H])([H])C([H])(C2=NC(=NO2)C2=C([H])C([H])=C(F)C([H])=C2Cl)C([H])([H])C1([H])[H]
[H]N(C(=O)C([H])(C([H])([H])[H])C([H])([H])[H])C1([H])C([H])([H])C([H])([H])N(C2=C([H])N=C(C3=C([H])C([H])=C(C([H])=C3[H])C(F)(F)F)C(=N2)C2=C([H])C([H])=NC([H])=C2Cl)C([H])([H])C1([H])[H]
[H]C1=NC([H])=C(Cl)C(=C1[H])C1=NC(=C([H])N=C1C1=C([H])C([H])=C(C([H])=C1[H])C(F)(F)F)N1C([H])([H])C([H])([H])S(=O)(=O)C([H])([H])C1([H])[H]
[H]N(C(=O)C(Cl)(C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)C1=C([H])N(C2=NC(=C([H])C([H])=C2C1=O)C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(F)C([H])=C1[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(\N=C1/C(=O)N(C2=C([H])C(OC([H])([H])[H])=C([H])C([H])=C12)C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C(=O)C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(\N=C1/C(=O)N(C2=C([H])C(OC([H])([H])[H])=C([H])C([H])=C12)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C(=O)C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]N(\N=C1/C(=O)N(C2=C([H])C(OC([H])([H])[H])=C([H])C([H])=C12)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C(=O)C([H])([H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]N(\N=C1/C(=O)N(C2=C([H])C(OC([H])([H])[H])=C([H])C([H])=C12)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C(=O)C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N(\N=C1/C(=O)N(C2=C([H])C(OC([H])([H])[H])=C([H])C([H])=C12)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C(=O)OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]OC(C(=O)N([H])\N=C1/C(=O)N(C2=C([H])C(OC([H])([H])[H])=C([H])C([H])=C12)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)C([H])([H])SC1=NN=C(N1C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C(OC([H])([H])[H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1C([H])([H])C([H])([H])[H]
[H]C1=C([H])C(C(=O)N2C3=C([H])C([H])=C(OC([H])([H])[H])C([H])=C3C(=C2C([H])([H])[H])C([H])([H])C(=O)N2C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])=C(Cl)C(Cl)=C1[H]
[H]C1=C([H])C(C(=O)N2C3=C([H])C([H])=C(OC([H])([H])[H])C([H])=C3C(=C2C([H])([H])[H])C([H])([H])N2C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])=C(Cl)C(Cl)=C1[H]
[H]N(\N=C1/C(=O)N(C2=C1C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C(=O)C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(\N=C1/C(=O)N(C2=C([H])C([H])=C(F)C([H])=C12)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C(=O)C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(\N=C1/C(=O)N(C2=C(Cl)C([H])=C([H])C([H])=C12)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C(=O)C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(\N=C1/C(=O)N(C2=C(C([H])=C([H])C([H])=C12)C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C(=O)C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(\N=C1/C(=O)N(C2=C([H])C([H])=C([H])C([H])=C12)C([H])([H])C1=C([H])C([H])=C(Cl)C([H])=C1[H])C(=O)C1=C([H])C([H])=C([H])C([H])=C1[H]
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[H]N(C(=O)C([H])([H])N1N=C(C(=N1)C1=C(Cl)C([H])=C(Cl)C([H])=C1[H])C1=C([H])C([H])=C(Cl)C([H])=C1Cl)C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)C([H])([H])N1N=C(C(=N1)C1=C(Cl)C([H])=C(Cl)C([H])=C1[H])C1=C([H])C([H])=C(Cl)C([H])=C1Cl)C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(C(=O)C([H])([H])N1N=C(C(=N1)C1=C(Cl)C([H])=C(Cl)C([H])=C1[H])C1=C([H])C([H])=C(Cl)C([H])=C1Cl)C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1F
[H]N(C(=O)C([H])([H])N1N=C(C(=N1)C1=C(Cl)C([H])=C(Cl)C([H])=C1[H])C1=C([H])C([H])=C(Cl)C([H])=C1Cl)C([H])([H])C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]N(C(=O)C([H])([H])N1N=C(C(=N1)C1=C(Cl)C([H])=C(Cl)C([H])=C1[H])C1=C([H])C([H])=C(Cl)C([H])=C1Cl)C([H])([H])C1=C([H])C([H])=C([H])C(F)=C1[H]
[H]N(C(=O)C([H])([H])C([H])([H])C1=NC(=NO1)C1=C([H])C([H])=C([H])C([H])=C1F)C1=C([H])C([H])=C2N(C3=C(C([H])=C([H])C([H])=C3[H])C2=C1[H])C([H])([H])C([H])([H])[H]
[H]N(C(=O)C1(C([H])([H])C1([H])[H])S(=O)(=O)C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])N=C2C([H])=C([H])C([H])=C([H])C2=C1[H]
[H]N(C(=O)C(C([H])([H])[H])(C([H])([H])[H])S(=O)(=O)C1=C([H])C([H])=C(C([H])=C1[H])C(F)(F)F)C1=C([H])N=C2C([H])=C([H])C([H])=C([H])C2=C1[H]
[H]N(C(=O)C(C([H])([H])[H])(C([H])([H])[H])S(=O)(=O)C1=C([H])C([H])=C(Cl)C([H])=C1[H])C1=NN=C(S1)C1=C([H])C([H])=C([H])C([H])=C1C([H])([H])[H]
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[H]N(C(=O)C(C([H])([H])[H])(C([H])([H])[H])S(=O)(=O)C1=C([H])C([H])=C(Cl)C([H])=C1[H])C1=C(OC(F)(F)F)C([H])=C(Cl)C([H])=C1[H]
[H]N(C(=O)C(C([H])([H])[H])(C([H])([H])[H])S(=O)(=O)C1=C([H])C([H])=C(Cl)C([H])=C1[H])C1=C([H])C(Br)=C(Cl)C([H])=C1[H]
[H]N(C(=O)C(C([H])([H])[H])(C([H])([H])[H])S(=O)(=O)C1=C([H])C([H])=C(Cl)C([H])=C1[H])C1=C([H])C([H])=C(Cl)C(=C1[H])C(F)(F)F
[H]N(C(=O)C(C([H])([H])[H])(C([H])([H])[H])S(=O)(=O)C1=C([H])C([H])=C(Cl)C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C(F)(F)F
[H]N(C(=O)C(C([H])([H])[H])(C([H])([H])[H])S(=O)(=O)C1=C([H])C([H])=C(Cl)C([H])=C1[H])C1=C([H])C([H])=C([H])C(=C1[H])C(F)(F)F
[H]N(C(=O)C(C([H])([H])[H])(C([H])([H])[H])S(=O)(=O)C1=C([H])C([H])=C(Cl)C([H])=C1[H])C1=C([H])N=C2C([H])=C([H])C([H])=C([H])C2=C1[H]
[H]N(C(=O)C(C([H])([H])[H])(C([H])([H])[H])S(=O)(=O)C1=C([H])C([H])=C(F)C([H])=C1[H])C1=C([H])N=C2C([H])=C([H])C([H])=C([H])C2=C1[H]
[H]N(C(=O)C(C([H])([H])[H])(C([H])([H])[H])S(=O)(=O)C1=C(Cl)C([H])=C(OC([H])([H])[H])C([H])=C1[H])C1=C([H])N=C2C([H])=C([H])C([H])=C([H])C2=C1[H]
[H]N(C(=O)C(C([H])([H])[H])(C([H])([H])[H])S(=O)(=O)C1=C(Cl)C([H])=C(F)C([H])=C1[H])C1=C([H])N=C2C([H])=C([H])C([H])=C([H])C2=C1[H]
[H]N(C(=O)C(C([H])([H])[H])(C([H])([H])[H])S(=O)(=O)C1=C(Cl)C([H])=C(C([H])=C1[H])C(F)(F)F)C1=C([H])N=C2C([H])=C([H])C([H])=C([H])C2=C1[H]
[H]N(C(=O)C([H])([H])C([H])([H])C([H])([H])C(\[H])=C(\[H])C([H])([H])C(\[H])=C(\[H])C([H])([H])C(\[H])=C(\[H])C([H])([H])C(\[H])=C(\[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C1=C([H])C2=C(N([H])N=C2[H])C([H])=C1[H]
[H]N(C(=O)C1(C([H])([H])C1([H])[H])S(=O)(=O)C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C2N(C3=C(C([H])=C([H])C([H])=C3[H])C2=C1[H])C([H])([H])C([H])([H])[H]
[H]C1=C([H])C([H])=C(\N=C2/OC([H])([H])C3(C([H])([H])N2C(=S)SC([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C3([H])[H])C([H])=C1[H]
[H]C1=C([H])C([H])=C(\N=C2/OC([H])([H])C3(C([H])([H])N2C(=S)SC([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C3([H])[H])C(OC([H])([H])[H])=C1[H]
[H]C1=C([H])C2=NON=C2C(\N=C2/OC([H])([H])C3(C([H])([H])N2C(=S)SC([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C3([H])[H])=C1[H]
[H]C1=C(N=C(S1)\N=C1/OC([H])([H])C2(C([H])([H])N1C(=S)SC([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]C1=C(ON=C1C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])\N=C1/OC([H])([H])C2(C([H])([H])N1C(=S)SC([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H]
[H]C1=C(ON=C1C(C([H])([H])C([H])([H])[H])(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H])\N=C1/OC([H])([H])C2(C([H])([H])N1C(=S)SC([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H]
[H]C1=C(ON=C1\N=C1/OC([H])([H])C2(C([H])([H])N1C(=S)SC([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])C([H])=C2C(\N=C3/OC([H])([H])C4(C([H])([H])N3C(=S)SC([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C4([H])[H])=C([H])C([H])=C(F)C2=C1[H]
[H]C1=C([H])C([H])=C2C(\N=C3/OC([H])([H])C4(C([H])([H])N3C(=S)SC([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C4([H])[H])=C([H])C([H])=C(Cl)C2=C1[H]
[H]C1=C([H])C([H])=C2C(C#N)=C([H])C([H])=C(\N=C3/OC([H])([H])C4(C([H])([H])N3C(=S)SC([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C4([H])[H])C2=C1[H]
[H]C1=C([H])C([H])=C2C(=C1[H])C(\N=C1/OC([H])([H])C3(C([H])([H])N1C(=S)SC([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C3([H])[H])=C([H])C([H])=C2[N+]([O-])=O
[H]C1=C([H])C([H])=C2C(=C([H])C([H])=C(\N=C3/OC([H])([H])C4(C([H])([H])N3C(=S)SC([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C4([H])[H])C2=C1[H])N(C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])C([H])=C2C(\N=C3/OC([H])([H])C4(C([H])([H])N3C(=S)SC([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C4([H])[H])=C([H])C([H])=C([H])C2=C1[H]
[H]C1=C([H])C([H])=C2C(\N=C3/SC([H])([H])C4(C([H])([H])N3C(=O)SC([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C4([H])[H])=C([H])C([H])=C([H])C2=C1[H]
[H]C1=C([H])C([H])=C2C(\N=C3/OC([H])([H])C4(C([H])([H])N3C(=O)SC([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C4([H])[H])=C([H])C([H])=C([H])C2=C1[H]
[H]N1\C(=N/C2=C([H])C([H])=C([H])C3=C([H])C([H])=C([H])C([H])=C23)N(C(=O)SC([H])([H])[H])C([H])([H])C2(C1([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H]
[H]C1=C([H])C2=C(C(\N=C3/OC([H])([H])C4(C([H])([H])N3C(=S)SC([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C4([H])[H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H]
[H]C1=C(Cl)C2=C(C(\N=C3/OC([H])([H])C4(C([H])([H])N3C(=S)SC([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C4([H])[H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H]
[H]C1=C(\N=C2/OC([H])([H])C3(C([H])([H])N2C(=S)SC([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C3([H])[H])C2=C(C(C#N)=C1[H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H]
[H]C1=NN(C([H])=N1)C([H])([H])C1=C(N(N=C1C1=NN=C(O1)C1(C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C(Cl)C([H])=C1Cl)C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]C1=NN(C([H])=N1)C([H])([H])C1=C(N(N=C1C1=NN=C(O1)C1(C([H])([H])C1([H])[H])C(F)(F)F)C1=C([H])C([H])=C(Cl)C([H])=C1Cl)C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]C1=NN(C([H])=N1)C([H])([H])C1=C(N(N=C1C1=NN=C(O1)C1(C([H])([H])[H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C(Cl)C([H])=C1Cl)C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]C1=NN=NN1C([H])([H])C1=C(N(N=C1C1=NN=C(O1)C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C(Cl)C([H])=C1Cl)C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]C1=NN(N=N1)C([H])([H])C1=C(N(N=C1C1=NN=C(O1)C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C(Cl)C([H])=C1Cl)C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]C1=C([H])N(N=N1)C([H])([H])C1=C(N(N=C1C1=NN=C(O1)C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C(Cl)C([H])=C1Cl)C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]C1=NN(C([H])=N1)C([H])([H])C1=C(N(N=C1C1=NN=C(O1)C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C(Cl)C([H])=C1Cl)C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]C1=C([H])N(C([H])=N1)C([H])([H])C1=C(N(N=C1C1=NN=C(O1)C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C(Cl)C([H])=C1Cl)C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]C1=NN(C([H])=C1[H])C([H])([H])C1=C(N(N=C1C1=NN=C(O1)C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C(Cl)C([H])=C1Cl)C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]C1=C([H])C([H])=C([H])C(OC([H])([H])C2=C(N(N=C2C2=NN=C(O2)C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C2=C([H])C([H])=C(Cl)C([H])=C2Cl)C2=C([H])C([H])=C(Cl)C([H])=C2[H])=N1
[H]C1=C([H])C([H])=C(OC([H])([H])C2=C(N(N=C2C2=NN=C(O2)C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C2=C([H])C([H])=C(Cl)C([H])=C2Cl)C2=C([H])C([H])=C(Cl)C([H])=C2[H])C([H])=C1[H]
[H]C1=C([H])C(=C([H])C([H])=C1Cl)C1=C(C(=NN1C1=C([H])C([H])=C(Cl)C([H])=C1Cl)C1=NN=C(O1)C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C#N
[H]C1=C([H])C(=C([H])C([H])=C1Cl)C1=C(C(=NN1C1=C([H])C([H])=C(Cl)C([H])=C1Cl)C1=NN=C(O1)C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])SC(=O)C([H])([H])[H]
[H]C1=C([H])C(=C([H])C([H])=C1Cl)C1=C(C(=NN1C1=C([H])C([H])=C(Cl)C([H])=C1Cl)C1=NN=C(O1)C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])OC(=O)C([H])([H])[H]
[H]C([H])=C(C1=C(N(N=C1C1=NN=C(O1)C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C(Cl)C([H])=C1Cl)C1=C([H])C([H])=C(Cl)C([H])=C1[H])C([H])([H])[H]
[H]OC(C1=C(N(N=C1C1=NN=C(O1)C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C(Cl)C([H])=C1Cl)C1=C([H])C([H])=C(Cl)C([H])=C1[H])(C([H])([H])[H])C([H])([H])[H]
[H]C([H])=C([H])C1=C(N(N=C1C1=NN=C(O1)C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C(Cl)C([H])=C1Cl)C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]C1=C([H])C(=C([H])C([H])=C1Cl)C1=C(C(=NN1C1=C([H])C([H])=C(Cl)C([H])=C1Cl)C1=NN=C(O1)C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])[C@]([H])(F)C([H])([H])[H]
[H]O[C@]([H])(C1=C(N(N=C1C1=NN=C(O1)C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C(Cl)C([H])=C1Cl)C1=C([H])C([H])=C(Cl)C([H])=C1[H])C([H])([H])[H]
[H]N(C(=O)OC([H])([H])[H])C([H])([H])C1=C(N(N=C1C1=NN=C(O1)C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C(Cl)C([H])=C1Cl)C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]C1=C([H])C(=C([H])C([H])=C1Cl)C1=C(C(=NN1C1=C([H])C([H])=C(Cl)C([H])=C1Cl)C1=NN=C(O1)C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])F
[H]C1=C([H])C(=C([H])C([H])=C1Cl)C1=C(C(=NN1C1=C([H])C([H])=C(Cl)C([H])=C1Cl)C1=NN=C(O1)C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])OC([H])([H])[H]
[H]OC([H])([H])C1=C(N(N=C1C1=NN=C(O1)C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C(Cl)C([H])=C1Cl)C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]N(C(=O)C([H])([H])N1N=C(C(=N1)C1=C(Cl)C([H])=C(Cl)C([H])=C1[H])C1=C([H])C([H])=C(Cl)C([H])=C1Cl)C([H])([H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]N(C(=O)C([H])([H])N1N=C(C(=N1)C1=C(Cl)C([H])=C(Cl)C([H])=C1[H])C1=C([H])C([H])=C(Cl)C([H])=C1Cl)C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1Cl
[H]N(C(=O)C([H])([H])N1N=C(C(=N1)C1=C(Cl)C([H])=C(Cl)C([H])=C1[H])C1=C([H])C([H])=C(Cl)C([H])=C1Cl)C([H])([H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]N(C(=O)C([H])([H])N1N=C(C(=N1)C1=C(Cl)C([H])=C(Cl)C([H])=C1[H])C1=C([H])C([H])=C(Cl)C([H])=C1Cl)C([H])([H])C1=C([H])C(F)=C([H])C([H])=C1F
[H]N(C(=O)C([H])([H])N1N=C(C(=N1)C1=C(Cl)C([H])=C(Cl)C([H])=C1[H])C1=C([H])C([H])=C(Cl)C([H])=C1Cl)C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C1=C([H])C2=C([H])C([H])=C3OC(=O)C(=C([H])C3=C2C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1OC([H])([H])[H]
[H]N(N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C(=O)C1=NN(C(=C1C([H])([H])[H])C1=C([H])C([H])=C(I)C([H])=C1[H])C1=C([H])C([H])=C(Cl)C([H])=C1Cl
[H]C(=O)N1C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C(=O)O[C@@]([H])(C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])[C@]1([H])OC(=O)[C@@]1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]N(C([H])=O)C([H])([H])C([H])([H])C(=O)O[C@@]([H])(C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])[C@]1([H])OC(=O)[C@@]1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]OC1=C([H])C2=C(C([H])=C1[H])C(=O)OC1=C2C(O[H])=C([H])C(=C1[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]C1=C(C(=O)C2=C([H])C([H])=C(C3=C([H])C([H])=C([H])C([H])=C23)C([H])([H])[H])C2=C([H])C([H])=C([H])C([H])=C2N1C([H])([H])C([H])([H])C([H])([H])[H]
[H]C1=C([H])C([H])=C2C(=C1[H])N(C(=C2C(=O)C1=C([H])C([H])=C([H])C2=C([H])C(OC([H])([H])[H])=C([H])C([H])=C12)C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]C1=C(OC([H])([H])[H])C2=C(OC(C([H])([H])[H])(C([H])([H])[H])[C@]3([H])C([H])([H])C([H])([H])C(=C([H])[C@@]23[H])C([H])([H])[H])C([H])=C1C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]C1=C([H])C([H])=C2C(=C1[H])N(C(=C2C(=O)C1=C(OC([H])([H])[H])C([H])=C([H])C2=C([H])C([H])=C([H])C([H])=C12)C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]OC1(C2=C(OC([H])([H])[H])C([H])=C(C([H])=C2OC([H])([H])[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]O[C@]1(C2=C(OC([H])([H])[H])C([H])=C(C([H])=C2OC([H])([H])[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[C@@]([H])(C([H])([H])[H])C1([H])[H]
[H]OC([H])([H])C1=C([H])[C@]([H])(C2=C(OC([H])([H])[H])C([H])=C(C([H])=C2OC([H])([H])[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])[C@@]2([H])C([H])([H])[C@]1([H])C2(C([H])([H])[H])C([H])([H])[H]
[H]C1=C(C(=O)C2=C(OC([H])([H])[H])C([H])=C3C([H])=C([H])C([H])=C([H])C3=C2[H])C2=C([H])C([H])=C([H])C([H])=C2N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]OC1=C2C(OC(C3=C2C([H])([H])C([H])([H])N(C([H])([H])[H])C3([H])[H])(C([H])([H])[H])C([H])([H])[H])=C([H])C(=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]N(C(=O)C([H])([H])N(C1=C(OC([H])([H])[H])C([H])=C([H])C(OC([H])([H])[H])=C1[H])S(=O)(=O)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=NC([H])=C1[H]
[H]C1=C([H])C(=C([H])C([H])=C1Cl)C1=C(C(=NN1C1=C([H])C([H])=C(Cl)C([H])=C1Cl)C1=NN=C(O1)C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C1([H])C([H])([H])C1([H])[H]
[H]C1=C([H])C(=C([H])C([H])=C1Cl)C1=C(C(=NN1C1=C([H])C([H])=C(Cl)C([H])=C1Cl)C1=NN=C(O1)C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])C(=C([H])C([H])=C1Cl)C1=C(C(=NN1C1=C([H])C([H])=C(Cl)C([H])=C1Cl)C1=NN=C(O1)C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H]
[H]C1=NN(C([H])=N1)C([H])([H])C1=C(N(N=C1C1=NN=C(O1)C1(C2=C([H])C([H])=C(Cl)C([H])=C2[H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C(Cl)C([H])=C1Cl)C1=C([H])C([H])=C(Br)C([H])=C1[H]
[H]C1=NN(C([H])=N1)C([H])([H])C1=C(N(N=C1C1=NN=C(O1)C1(C2=C([H])C([H])=C(C([H])=C2[H])C([H])([H])[H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C(Cl)C([H])=C1Cl)C1=C([H])C([H])=C(Br)C([H])=C1[H]
[H]C1=NN(C([H])=N1)C([H])([H])C1=C(N(N=C1C1=NN=C(O1)C1(C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C(Cl)C([H])=C1Cl)C1=C([H])C([H])=C(Br)C([H])=C1[H]
[H]C1=NN(C([H])=N1)C([H])([H])C1=C(N(N=C1C1=NN=C(O1)C1(C([H])([H])C1([H])[H])C(F)(F)F)C1=C([H])C([H])=C(Cl)C([H])=C1Cl)C1=C([H])C([H])=C(Br)C([H])=C1[H]
[H]C1=NN(C([H])=N1)C([H])([H])C1=C(N(N=C1C1=NN=C(O1)C1(C([H])([H])[H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C(Cl)C([H])=C1Cl)C1=C([H])C([H])=C(Br)C([H])=C1[H]
[H]C1=NN(C([H])=N1)C([H])([H])C1=C(N(N=C1C1=NN=C(O1)C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C(Cl)C([H])=C1Cl)C1=C([H])C([H])=C(Br)C([H])=C1[H]
[H]C1=NN(C([H])=N1)C([H])([H])C1=C(N(N=C1C1=NN=C(O1)C1(C2=C([H])C([H])=C(Cl)C([H])=C2[H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C(Cl)C([H])=C1Cl)C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]C1=NN(C([H])=N1)C([H])([H])C1=C(N(N=C1C1=NN=C(O1)C1(C2=C([H])C([H])=C(C([H])=C2[H])C([H])([H])[H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C(Cl)C([H])=C1Cl)C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]N1C(=C([H])N=C1C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C1=C([H])C(=C(C([H])=C1[H])C([H])([H])[H])S(=O)(=O)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]C1=C([H])C(=C(C([H])=C1C1=NOC(=N1)C([H])([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])S(=O)(=O)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C([H])([H])[H]
[H]N(C(=O)[C@]1([H])C([H])([H])[C@@]2(O[C@@]1(C([H])([H])[H])C([H])([H])C2([H])[H])C([H])([H])[H])C1=C([H])C(=C(C([H])=C1[H])C([H])([H])[H])S(=O)(=O)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]N(C(=O)C1=C([H])C(=C(C([H])=C1[H])C([H])([H])[H])S(=O)(=O)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])[C@]1([H])C(C([H])([H])[H])(C([H])([H])[H])[C@]2([H])C([H])([H])C([H])([H])[C@@]1(C([H])([H])[H])C2([H])[H]
[H]N1N=C(N=C1C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C1=C([H])C(=C(C([H])=C1[H])C([H])([H])[H])S(=O)(=O)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]N1C([H])=C(N=C1C1=C([H])C(=C(C([H])=C1[H])C([H])([H])[H])S(=O)(=O)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C([H])([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]OC1=C([H])C(=C([H])C(O[H])=C1C1=C([H])C(Cl)=C([H])C(Cl)=C1[H])C(C1=C([H])C([H])=C([H])C([H])=C1[H])(C([H])([H])[H])C([H])([H])[H]
[H]O[C@@]([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C(OC([H])([H])[H])=C(C(OC([H])([H])[H])=C1[H])C1=C([H])C(Cl)=C([H])C(Cl)=C1[H]
[H]OC1=C([H])C(=C([H])C(OC([H])([H])[H])=C1C1=C([H])C(Cl)=C([H])C(Cl)=C1[H])C(=O)C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)C([H])(C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C1=C([H])C(=C(C([H])=C1[H])C([H])([H])[H])S(=O)(=O)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]C1=C(N=C(S1)C1=C([H])C(=C(C([H])=C1[H])C([H])([H])[H])S(=O)(=O)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C([H])([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]O[C@]([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1C(F)(F)F
[H]C1=C([H])C([H])=C(C([H])=C1[H])[C@]1([H])OC([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C(C([H])=C2[H])C2=C([H])C([H])=C([H])C([H])=C2C(F)(F)F)C1([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])[C@@]1([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C(C([H])=C2[H])C2=C([H])C([H])=C([H])C([H])=C2C(F)(F)F)C([H])([H])C([H])([H])C1([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])[C@]1([H])OC([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C(C([H])=C2[H])C2=C([H])C([H])=C([H])C([H])=C2Cl)C1([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])[C@]1([H])OC([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C(C([H])=C2[H])C2=C([H])C([H])=C([H])C(Cl)=C2Cl)C1([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])[C@]1([H])OC([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C(C([H])=C2[H])C2=C([H])C(=C([H])C([H])=C2Cl)C([H])([H])[H])C1([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])[C@]1([H])OC([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C(C([H])=C2[H])C2=C([H])C([H])=C([H])C([H])=C2C#N)C1([H])[H]
[H]N(C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1C([H])([H])C([H])([H])O[C@@]([H])(C2=C([H])C([H])=C([H])C([H])=C2[H])C1([H])[H]
[H]N(C1=NC([H])=C(C([H])=C1[H])C([H])([H])N1C([H])([H])C([H])([H])O[C@@]([H])(C2=C([H])C([H])=C([H])C([H])=C2[H])C1([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C1=NC([H])=C(C([H])=C1[H])C([H])([H])N1C([H])([H])C([H])([H])O[C@@]([H])(C2=C([H])C([H])=C([H])C([H])=C2[H])C1([H])[H])C1=C([H])C([H])=C([H])C(Cl)=C1Cl
[H]N(C1=NC([H])=C(C([H])=C1[H])C([H])([H])N1C([H])([H])C([H])([H])O[C@@]([H])(C2=C([H])C([H])=C([H])C([H])=C2[H])C1([H])[H])C1=C([H])C([H])=C([H])C([H])=C1Cl
[H]N(C1=NC([H])=C(C([H])=C1[H])C([H])([H])N1C([H])([H])C([H])([H])O[C@@]([H])(C2=C([H])C([H])=C([H])C([H])=C2[H])C1([H])[H])C1=C([H])C([H])=C([H])C(Cl)=C1[H]
[H]N(C1=NC([H])=C(C([H])=C1[H])C([H])([H])N1C([H])([H])C([H])([H])O[C@@]([H])(C2=C([H])C([H])=C([H])C([H])=C2[H])C1([H])[H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]N(C1=NC([H])=C(C([H])=C1[H])C([H])([H])N1C([H])([H])C([H])([H])O[C@@]([H])(C2=C([H])C([H])=C([H])C([H])=C2[H])C1([H])[H])C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]N(C1=NC([H])=C(C([H])=C1[H])C([H])([H])N1C([H])([H])C([H])([H])O[C@@]([H])(C2=C([H])C([H])=C([H])C([H])=C2[H])C1([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H]
[H]N(C1=NC([H])=C(C([H])=C1[H])C([H])([H])N1C([H])([H])C([H])([H])O[C@@]([H])(C2=C([H])C([H])=C([H])C([H])=C2[H])C1([H])[H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]N(C1=NC([H])=C(C([H])=C1[H])C([H])([H])N1C([H])([H])C([H])([H])O[C@@]([H])(C2=C([H])C([H])=C([H])C([H])=C2[H])C1([H])[H])C1=C([H])C([H])=C(Cl)C(Cl)=C1[H]
[H]N(C1=NC([H])=C(C([H])=C1[H])C([H])([H])N1C([H])([H])C([H])([H])O[C@@]([H])(C2=C([H])C([H])=C([H])C([H])=C2[H])C1([H])[H])C1=C([H])C([H])=C(Cl)C([H])=C1Cl
[H]N(C(=O)C1=C([H])C2=C([H])C([H])=C([H])N=C2N(C1=O)C([H])([H])C1=C([H])C([H])=C(F)C([H])=C1[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(C(=O)C1=C([H])C2=C([H])C([H])=C([H])N=C2N(C1=O)C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])[C@@]1([H])C([H])([H])C([H])([H])[C@]([H])(C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N(C(=O)C1=C([H])C2=C([H])C([H])=C([H])N=C2N(C1=O)C([H])([H])C1=C([H])C([H])=C(F)C([H])=C1[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(C(=O)C1=C([H])C2=C([H])C([H])=C([H])N=C2N(C1=O)C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])[C@@]1([H])C([H])([H])C([H])([H])[C@@]([H])(C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N(C(=O)C1=C([H])C2=C([H])C([H])=C([H])N=C2N(C1=O)C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(C(=O)C1=C([H])C2=C([H])C([H])=C([H])N=C2N(C1=O)C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]OC1=C([H])C(=C([H])C(O[H])=C1C1=C([H])C(Cl)=C([H])C(Cl)=C1[H])C(=O)C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C1=C([H])C2=C(C([H])=C([H])C(=C2OC1=O)C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])C(OC([H])([H])[H])=C(C([H])=C1[H])C([H])([H])C1=C([H])C2=C(C([H])=C([H])C(=C2OC1=O)C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])C(OC([H])([H])[H])=C(C([H])=C1[H])C([H])([H])C1=C([H])C2=C(OC([H])([H])[H])C([H])=C([H])C(=C2OC1=O)C([H])([H])[H]
[H]C1=C([H])C(=C(OC([H])([H])[H])C([H])=C1OC([H])([H])[H])C([H])([H])C1=C([H])C2=C(OC([H])([H])[H])C([H])=C(C([H])=C2OC1=O)C([H])([H])[H]
[H]C1=C([H])C(OC([H])([H])[H])=C(C([H])=C1[H])C([H])([H])C1=C([H])C2=C(OC([H])([H])[H])C([H])=C([H])C([H])=C2OC1=O
[H]C1=C([H])C(=C([H])C([H])=C1OC([H])([H])[H])C([H])([H])C1=C([H])C2=C(OC([H])([H])[H])C([H])=C(C([H])=C2OC1=O)C([H])([H])[H]
[H]C1=C([H])C(=C([H])C(OC([H])([H])[H])=C1[H])C([H])([H])C1=C([H])C2=C(OC([H])([H])[H])C([H])=C(C([H])=C2OC1=O)C([H])([H])[H]
[H]C1=C([H])C(OC([H])([H])[H])=C(C([H])=C1[H])C([H])([H])C1=C([H])C2=C(OC([H])([H])[H])C([H])=C(C([H])=C2OC1=O)C([H])([H])[H]
[H]OC1=C(C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])C2=C(OC([H])([H])[H])C([H])=C(C([H])=C2OC1=O)C([H])([H])[H]
[H]C1=C([H])C(=C([H])C([H])=C1Cl)C([H])([H])C1=C([H])C2=C(OC([H])([H])[H])C([H])=C(C([H])=C2OC1=O)C([H])([H])[H]
[H]C1=C([H])C(Cl)=C(C([H])=C1[H])C([H])([H])C1=C([H])C2=C(OC([H])([H])[H])C([H])=C(C([H])=C2OC1=O)C([H])([H])[H]
[H]C1=C([H])C(=C([H])C([H])=C1C([H])([H])[H])C([H])([H])C1=C([H])C2=C(OC([H])([H])[H])C([H])=C(C([H])=C2OC1=O)C([H])([H])[H]
[H]C1=C([H])C(=C(C([H])=C1[H])C([H])([H])C1=C([H])C2=C(OC([H])([H])[H])C([H])=C(C([H])=C2OC1=O)C([H])([H])[H])C([H])([H])[H]
[H]C1=C(N=C(S1)C1=C([H])C(=C(C([H])=C1[H])C([H])([H])[H])S(=O)(=O)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]C1=C(N=C(S1)C1=C([H])C(=C(C([H])=C1[H])C([H])([H])[H])S(=O)(=O)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])C(=C(C([H])=C1C1=NN(N=N1)C([H])([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])S(=O)(=O)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C([H])([H])[H]
[H]C1=C([H])C(=C(C([H])=C1C1=NN(N=N1)C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])S(=O)(=O)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C([H])([H])[H]
[H]N(N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C(=O)C1=C(N(C(=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C(Cl)C([H])=C1[H])C([H])([H])[H]
[H]N1N=NC(=N1)C1=C([H])C(=C(C([H])=C1[H])C([H])([H])[H])S(=O)(=O)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]N1N=C(N=C1C([H])([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C1=C([H])C(=C(C([H])=C1[H])C([H])([H])[H])S(=O)(=O)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]N1N=C(N=C1C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C1=C([H])C(=C(C([H])=C1[H])C([H])([H])[H])S(=O)(=O)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]C1=C([H])C(=C([H])C(OC([H])([H])[H])=C1[H])N1C(=NN(C2=C([H])C([H])=C(Cl)C([H])=C2[H])[C@]1([H])C1=C([H])C([H])=C(C([H])=C1[H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C(=O)C([H])([H])[H]
[H]C1=C(N(N=C1C1=C(Cl)C([H])=C([H])C([H])=C1[H])C1=C(C([H])=C(C([H])=C1[H])C([H])([H])[H])C([H])([H])[H])C(=O)N1C([H])([H])C([H])([H])N(C(=O)OC([H])([H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]OC1=C([H])C([H])=C(N([H])C(=O)C([H])([H])C([H])([H])C([H])([H])C(\[H])=C(\[H])C([H])([H])C(\[H])=C(\[H])C([H])([H])C(\[H])=C(\[H])C([H])([H])C(\[H])=C(\[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])=C1OC([H])([H])[H]
[H]N(C(=O)C1=C([H])C(=C(Br)C([H])=C1[H])S(=O)(=O)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N1N=C(C([H])=C1C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C1=C([H])C(=C(C([H])=C1[H])C([H])([H])[H])S(=O)(=O)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]N(C(=O)[C@]1([H])C(C([H])([H])[H])(C([H])([H])[H])[C@]2([H])C([H])([H])C([H])([H])[C@@]1(C([H])([H])[H])C2([H])[H])C1=C([H])C(=C(C([H])=C1[H])C([H])([H])[H])S(=O)(=O)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]N(C(=O)C1=C([H])C(=C(C([H])=C1[H])C([H])([H])[H])S(=O)(=O)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C([H])(C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])C(=C(C([H])=C1C1=NOC(=N1)C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])S(=O)(=O)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C([H])([H])[H]
[H]C1=C([H])C(=C(C([H])=C1C1=NOC(=N1)C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])S(=O)(=O)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C([H])([H])[H]
[H]N1N=C(C([H])=C1C([H])([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C1=C([H])C(=C(C([H])=C1[H])C([H])([H])[H])S(=O)(=O)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]N1N=C(C([H])=C1C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C1=C([H])C(=C(C([H])=C1[H])C([H])([H])[H])S(=O)(=O)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]N1C([H])=C(N=C1C1=C([H])C(=C(C([H])=C1[H])C([H])([H])[H])S(=O)(=O)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C(Cl)C([H])=C1[H])C1=C([H])C(=C(C([H])=C1[H])C([H])([H])[H])S(=O)(=O)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]OC1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N([H])C(=O)C([H])([H])C([H])([H])C([H])([H])C(\[H])=C(\[H])C([H])([H])C(\[H])=C(\[H])C([H])([H])C(\[H])=C(\[H])C([H])([H])C(\[H])=C(\[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]N([H])C1=C(N([H])C(=C1C(=O)C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)C1=C(N(C(=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C(Cl)C([H])=C1[H])C([H])([H])[H])[C@@]1([H])C([H])([H])[C@]2([H])C([H])([H])C([H])([H])[C@@]1([H])C2([H])[H]
[H]N([H])C1=C(N(C(=C1C(=O)C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(Cl)C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C1=C(N(C(=C1C(=O)C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(Cl)C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)C1=C(N(C(=C1Br)C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C(Cl)C([H])=C1[H])C([H])([H])[H])[C@@]1([H])[C@@]2([H])C([H])([H])[C@]3([H])C([H])([H])[C@]([H])(C2([H])[H])C([H])([H])[C@@]1([H])C3([H])[H]
[H]N(C(=O)[C@@]1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1(C([H])([H])[H])C([H])([H])[H])C1=C([H])C(=C(C([H])=C1[H])C([H])([H])[H])S(=O)(=O)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]N(C(=O)C(C([H])([H])[H])(C(F)(F)F)C(F)(F)F)C1=C([H])C(=C(C([H])=C1[H])C([H])([H])[H])S(=O)(=O)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]N(C(=O)C1([H])C(C([H])([H])[H])(C([H])([H])[H])C1(C([H])([H])[H])C([H])([H])[H])C1=C([H])C(=C(C([H])=C1[H])C([H])([H])[H])S(=O)(=O)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]N(C(=O)C1(C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C1=C([H])C(=C(C([H])=C1[H])C([H])([H])[H])S(=O)(=O)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]N(C(=O)C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C1=C([H])C(=C(C([H])=C1[H])C([H])([H])[H])S(=O)(=O)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C([H])C(Cl)=C1[H])C1=C([H])C(=C(C([H])=C1[H])C([H])([H])[H])S(=O)(=O)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C([H])C([H])=C1Cl)C1=C([H])C(=C(C([H])=C1[H])C([H])([H])[H])S(=O)(=O)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]N(C(=O)C1=C([H])C2=C([H])C([H])=C([H])N=C2N(C1=O)C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]N(C(=O)C1=C([H])C2=C([H])C([H])=C([H])N=C2N(C1=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]OC1=C([H])C(=C([H])C2=C1[C@]1([H])C([H])([H])C(=C([H])C([H])([H])[C@@]1([H])C(O2)(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C(C1=C([H])C([H])=C([H])C(N([H])C(=O)C([H])([H])[H])=C1[H])(C([H])([H])[H])C([H])([H])[H]
[H]OC1=C([H])C(C([H])=C2[C@@]3([H])C([H])([H])[C@@]4([H])C([H])([H])[C@]2([H])C([H])([H])[C@@]([H])(C3([H])[H])C4([H])[H])=C([H])C2=C1[C@]1([H])C([H])([H])C(=C([H])C([H])([H])[C@@]1([H])C(O2)(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H]
[H]OC1=C([H])C(=C([H])C2=C1[C@]1([H])C([H])([H])C(=C([H])C([H])([H])[C@@]1([H])C(O2)(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])[C@]12C([H])([H])[C@@]3([H])C([H])([H])[C@]([H])(C([H])([H])[C@]([H])(C3([H])[H])C1([H])[H])C2([H])[H]
[H]C1=C([H])C(=C([H])C([H])=C1Cl)C1=C(C(=NN1C1=C([H])C([H])=C(Cl)C([H])=C1Cl)C1=NC(=O)C(N1C([H])([H])C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])C(=C([H])C([H])=C1Cl)C1=C(C(=NN1C1=C([H])C([H])=C(Cl)C([H])=C1Cl)C1=NC(=O)C(N1C([H])([H])C([H])([H])C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])C(=C([H])C([H])=C1Cl)C1=C(C(=NN1C1=C([H])C([H])=C(Cl)C([H])=C1Cl)C1=NC(=O)C(N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H]
[H]C([H])=C([H])C([H])([H])N1C(=NC(=O)C1(C([H])([H])[H])C([H])([H])[H])C1=NN(C(=C1C([H])([H])[H])C1=C([H])C([H])=C(Cl)C([H])=C1[H])C1=C([H])C([H])=C(Cl)C([H])=C1Cl
[H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1C(=NC(=O)C1(C([H])([H])[H])C([H])([H])[H])C1=NN(C(=C1C([H])([H])[H])C1=C([H])C([H])=C(Cl)C([H])=C1[H])C1=C([H])C([H])=C(Cl)C([H])=C1Cl
[H]C1=C(N(N=C1C1=NC(=O)C(N1C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C(Cl)C([H])=C1Cl)C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]C1=C([H])C(=C([H])C([H])=C1Cl)C1=C(C(=NN1C1=C([H])C([H])=C(Cl)C([H])=C1Cl)C1=NC(=O)C(N1C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])[H]
[H]C1=C([H])C(=C([H])C([H])=C1Br)C1=C(C(=NN1C1=C([H])C([H])=C(Cl)C([H])=C1Cl)C1=NC(=O)C(N1C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])C(=C([H])C([H])=C1Cl)C1=C(C(=NN1C1=C([H])C([H])=C(Cl)C([H])=C1Cl)C1=NC(=O)C(N1C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H]
[H]N1C([H])([H])C([H])([H])N(C2=NC(=NC3=NC(C4=C([H])C([H])=C([H])C([H])=C4Cl)=C(C([H])=C23)C2=C([H])C([H])=C(Cl)C([H])=C2[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]C1=C([H])C([H])=C(C(Cl)=C1[H])C1=C(C([H])=C2C(=N1)N=C(N=C2N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]N(C1=NC(=NC2=NC(C3=C([H])C([H])=C([H])C([H])=C3Cl)=C(C([H])=C12)C1=C([H])C([H])=C(Cl)C([H])=C1[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C1=NC(=NC2=NC(C3=C([H])C([H])=C([H])C([H])=C3Cl)=C(C([H])=C12)C1=C([H])C([H])=C(Cl)C([H])=C1[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])C([H])=C(C(Cl)=C1[H])C1=C(C([H])=C2C(OC([H])([H])[H])=NC(=NC2=N1)C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]N([H])C1=NC(=NC2=NC(C3=C([H])C([H])=C([H])C([H])=C3Cl)=C(C([H])=C12)C1=C([H])C([H])=C(Cl)C([H])=C1[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]OC1=NC(=NC2=NC(C3=C([H])C([H])=C([H])C([H])=C3Cl)=C(C([H])=C12)C1=C([H])C([H])=C(Cl)C([H])=C1[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]OC1=NC(=NC2=NC(C3=C([H])C([H])=C(Cl)C([H])=C3Cl)=C(C([H])=C12)C1=C([H])C([H])=C(Cl)C([H])=C1[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]N([H])C1=NC(=NC2=NC(C3=C([H])C([H])=C([H])C([H])=C3Cl)=C(C([H])=C12)C1=C([H])C([H])=C(Cl)C([H])=C1[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]N([H])C1=NC(=NC2=NC(C3=C([H])C([H])=C(Cl)C([H])=C3Cl)=C(C([H])=C12)C1=C([H])C([H])=C(Cl)C([H])=C1[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]OC1=NC(=NC2=NC(C3=C([H])C([H])=C([H])C([H])=C3Cl)=C(C([H])=C12)C1=C([H])C([H])=C(Cl)C([H])=C1[H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]N([H])C1=NC(=NC2=NC(C3=C([H])C([H])=C([H])C([H])=C3Cl)=C(C([H])=C12)C1=C([H])C([H])=C(Cl)C([H])=C1[H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]N(N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C(=O)C1=NN(C(C2=C([H])C([H])=C(Cl)S2)=C1C([H])([H])[H])C1=C([H])C([H])=C(Cl)C([H])=C1Cl
[H]OC1=NC(=NC2=NC(C3=C([H])C([H])=C([H])C([H])=C3Cl)=C(C([H])=C12)C1=C([H])C([H])=C(Cl)C([H])=C1[H])C([H])([H])[H]
[H]C1=C([H])C([H])=C(C(Cl)=C1[H])C1=C(C([H])=C2C(=N1)N=C(N=C2C1=C([H])C([H])=C(F)C([H])=C1[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]N(C(=O)C1=C(N(N=C1C1=NN=C(O1)C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C(Cl)C([H])=C1Cl)C1=C([H])C([H])=C(Cl)C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)C1=C(N(N=C1C1=NN=C(O1)C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C(Cl)C([H])=C1Cl)C1=C([H])C([H])=C(Cl)C([H])=C1[H])C1=NC([H])=C([H])C([H])=C1[H]
[H]N(C(=O)C1=C(N(N=C1C1=NN=C(O1)C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C(Cl)C([H])=C1Cl)C1=C([H])C([H])=C(Br)C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)C1=C(N(N=C1C1=NN=C(O1)C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C(Cl)C([H])=C1Cl)C1=C([H])C([H])=C(Br)C([H])=C1[H])C1=NC([H])=C([H])C([H])=C1[H]
[H]N(C(=O)C1=C(N(N=C1C1=NN=C(O1)C1(C([H])([H])C1([H])[H])C(F)(F)F)C1=C([H])C([H])=C(Cl)C([H])=C1Cl)C1=C([H])C([H])=C(Br)C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C1=C([H])C([H])=C(C(Cl)=C1[H])C1=C(C([H])=C2C(N=C(N=C2N(C([H])([H])[H])C([H])([H])[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])=N1)C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]OC([H])([H])C(F)(F)C([H])([H])N([H])C1=NC(=NC2=NC(C3=C([H])C([H])=C([H])C([H])=C3Cl)=C(C([H])=C12)C1=C([H])C([H])=C(Cl)C([H])=C1[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]C1=NC(=NO1)C([H])([H])OC1=NC(=NC2=NC(C3=C([H])C([H])=C([H])C([H])=C3Cl)=C(C([H])=C12)C1=C([H])C([H])=C(Cl)C([H])=C1[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]C1=NC(=NO1)C([H])([H])N1C(=O)C2=C([H])C(C3=C([H])C([H])=C(Cl)C([H])=C3[H])=C(N=C2N=C1C([H])(C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1Cl
[H]N1N=C2N(C1=O)C(=NC1=NC(C3=C([H])C([H])=C([H])C([H])=C3Cl)=C(C([H])=C21)C1=C([H])C([H])=C(Cl)C([H])=C1[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]N1N=C2N(C1=O)C(=NC1=NC(C3=C([H])C([H])=C([H])C([H])=C3Cl)=C(C([H])=C21)C1=C([H])C(Cl)=C([H])C([H])=C1[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]OC1=C([H])C(OC([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C(=O)N([H])C([H])([H])C([H])([H])O[H])=C([H])C(OC([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])=C1[H]
[H]OC1=C([H])C(OC([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C(=O)N([H])C([H])([H])C([H])([H])O[H])=C([H])C(=C1[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]OC1=C([H])C(OC([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C(=O)N([H])C2([H])C([H])([H])C2([H])[H])=C([H])C(OC([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])=C1[H]
[H]OC1=C([H])C(OC([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C(=O)N([H])C2([H])C([H])([H])C2([H])[H])=C([H])C(=C1[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]OC1=C([H])C(OC([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C(=O)N([H])C([H])([H])C2([H])C([H])([H])C2([H])[H])=C([H])C(OC([H])([H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])=C1[H]
[H]OC1=C([H])C(OC([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C(=O)N([H])C([H])([H])C2([H])C([H])([H])C2([H])[H])=C([H])C(=C1[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]N(N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C(=O)C1=NN(C(C2=C([H])C([H])=C([H])S2)=C1C([H])([H])[H])C1=C([H])C([H])=C(Cl)C([H])=C1Cl
[H]OC1=C([H])C(OC([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C(=O)N([H])C([H])([H])C([H])([H])C2=C([H])C([H])=C(O[H])C(O[H])=C2[H])=C([H])C(=C1[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]OC1=C([H])C(OC([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C(=O)N([H])C([H])([H])C2=C([H])C([H])=C(O[H])C(OC([H])([H])[H])=C2[H])=C([H])C(=C1[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]N([H])C1=NC(=NC2=NC(C3=C([H])C([H])=C([H])C([H])=C3Cl)=C(C([H])=C12)C1=C([H])C([H])=C(Cl)C([H])=C1[H])C([H])([H])[H]
[H]OC1=NC(=NC2=NC(C3=C([H])C([H])=C([H])C([H])=C3Cl)=C(C([H])=C12)C1=C([H])C([H])=C(Cl)C([H])=C1[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N1N=C2N(C1=O)C(=NC1=NC(C3=C([H])C([H])=C([H])C([H])=C3C#N)=C(C([H])=C21)C1=C([H])C([H])=C(Cl)C([H])=C1[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]N1N=C2N(C1=O)C(=NC1=NC(C3=C([H])C([H])=C([H])C([H])=C3Cl)=C(C([H])=C21)C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]N1N=C2N(C1=O)C(=NC1=NC(C3=C([H])C([H])=C([H])C([H])=C3Cl)=C(C([H])=C21)C1=C([H])C([H])=C(C([H])=C1[H])C(F)(F)F)C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]N1N=C2N(C1=O)C(=NC1=NC(C3=C([H])C([H])=C([H])C([H])=C3Cl)=C(C([H])=C21)C1=C([H])C([H])=C(C([H])=C1[H])C(=O)C([H])([H])[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]N1N=C2N(C1=O)C(=NC1=NC(C3=C([H])C([H])=C([H])C([H])=C3Cl)=C(C([H])=C21)C1=C([H])C([H])=C(C([H])=C1[H])N(C([H])([H])[H])C([H])([H])[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]C1=NN=C2N1C(=NC1=NC(C3=C([H])C([H])=C([H])C([H])=C3Cl)=C(C([H])=C21)C1=C([H])C([H])=C(Cl)C([H])=C1[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])C2=C([H])C([H])=C([H])C(C(=O)N3C4=C(C([H])=C(OC([H])([H])[H])C([H])=C4[H])C(=C3C([H])([H])[H])C([H])([H])C(=O)OC([H])([H])[H])=C2C([H])=C1[H]
[H]C1=C([H])C(OC([H])([H])[H])=C([H])C2=C1N(C(=O)C1=C([H])C([H])=C(Cl)C([H])=C1[H])C(=C2C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C([H])([H])[H]
[H]C1=C([H])C(OC([H])([H])[H])=C([H])C2=C1N(C(=O)C1=C([H])C([H])=C(Cl)C([H])=C1[H])C(=C2C([H])([H])C(=O)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C([H])([H])[H]
[H]C1=C([H])C(Cl)=C([H])C(=C1[H])C(=O)N1C2=C(C([H])=C(OC([H])([H])[H])C([H])=C2[H])C(=C1C([H])([H])[H])C([H])([H])C(=O)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]C1=C([H])C2=C(C([H])=C1[H])C(=C(N2C(=O)C1=C([H])C([H])=C([H])C2=C1C([H])=C([H])C([H])=C2[H])C([H])([H])[H])C([H])([H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]C1=C([H])C([H])=C2C(=C1[H])N(C(=C2C(=O)C1=C2C([H])=C([H])C([H])=C([H])C2=C([H])C([H])=C1[H])C([H])([H])[H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]C1=C([H])C2=C(C([H])=C1[H])C(=C(N2C(=O)C1=C([H])C([H])=C([H])C(Cl)=C1Cl)C([H])([H])[H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]C1=C([H])C(OC([H])([H])[H])=C([H])C2=C1N(C(=O)C1=C([H])C([H])=C(Cl)C([H])=C1[H])C(=C2C([H])([H])C(=O)OC([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])C(Cl)=C(C(=O)N2C3=C(C([H])=C(OC([H])([H])[H])C([H])=C3[H])C(=C2C([H])([H])[H])C([H])([H])C(=O)N2C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])C(Cl)=C1[H]
[H]C1=C([H])C([H])=C(C(=O)N2C3=C(C([H])=C(OC([H])([H])[H])C([H])=C3[H])C(=C2C([H])([H])[H])C([H])([H])C(=O)N2C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])C(Cl)=C1[H]
[H]C1=C([H])C2=C(C([H])=C1[H])C(=C(N2C1=C([H])C([H])=C([H])C2=C1C([H])=C([H])C([H])=C2[H])C([H])([H])[H])C([H])([H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]C1=C([H])C(OC([H])([H])[H])=C([H])C2=C1N(C(=O)C1=C([H])C([H])=C(F)C([H])=C1Cl)C(=C2C([H])([H])C(=O)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C([H])([H])[H]
[H]C1=C([H])C(Cl)=C(Cl)C(=C1[H])C([H])([H])N1C2=C(C([H])=C(OC([H])([H])[H])C([H])=C2[H])C(=C1C([H])([H])[H])C([H])([H])C(=O)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]C1=C([H])C([H])=C(C(=O)N2C3=C(C([H])=C(OC([H])([H])[H])C([H])=C3[H])C(=C2C([H])([H])[H])C([H])([H])C(=O)OC([H])([H])[H])C(Cl)=C1[H]
[H]C1=C([H])C(=C([H])C([H])=C1Cl)C1=C(C(=NN1C1=C([H])C([H])=C(Cl)C([H])=C1Cl)C1=NC(=O)C(N1C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C1([H])C([H])([H])C1([H])[H]
[H]N1C(=NC(C1=O)(C([H])([H])[H])C([H])([H])[H])C1=NN(C(=C1C([H])([H])[H])C1=C([H])C([H])=C(Cl)C([H])=C1[H])C1=C([H])C([H])=C(Cl)C([H])=C1Cl
[H]N1C(=NC2(C1=O)C([H])([H])C([H])([H])C2([H])[H])C1=NN(C(=C1C([H])([H])C([H])([H])[H])C1=C([H])C([H])=C(Cl)C([H])=C1[H])C1=C([H])C([H])=C(Cl)C([H])=C1Cl
[H]C1=C([H])C(=C([H])C([H])=C1Br)C1=C(C(=NN1C1=C([H])C([H])=C(Cl)C([H])=C1Cl)C1=NC(=O)C(N1C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])[H]
[H]C1=C([H])C(=C([H])C([H])=C1OC([H])([H])[H])C1=C(C(=NN1C1=C([H])C([H])=C(Cl)C([H])=C1Cl)C1=NC(=O)C(N1C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])C(=C([H])C([H])=C1C1=C(C(=NN1C1=C([H])C([H])=C(Cl)C([H])=C1Cl)C1=NC(=O)C(N1C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C(F)(F)F
[H]C1=C([H])C(=C([H])C([H])=C1Cl)C1=C(C(=NN1C1=C([H])C([H])=C(Cl)C([H])=C1Cl)C1=NC(=S)C(N1C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])C(=C([H])C([H])=C1Cl)C1=C(C(=NN1C1=C([H])C([H])=C(Cl)C([H])=C1Cl)C1=NC(=S)C(N1C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])[H]
[H]C1=C([H])C(=C([H])C([H])=C1Cl)C1=C(Br)C(=NN1C1=C([H])C([H])=C(Cl)C([H])=C1Cl)C1=NC(=O)C(N1C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]N1C(=NC2(C1=O)C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C1=NN(C(=C1C([H])([H])C([H])([H])[H])C1=C([H])C([H])=C(Cl)C([H])=C1[H])C1=C([H])C([H])=C(Cl)C([H])=C1Cl
[H]N1C(=NC2(C1=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C1=NN(C(=C1C([H])([H])C([H])([H])[H])C1=C([H])C([H])=C(Cl)C([H])=C1[H])C1=C([H])C([H])=C(Cl)C([H])=C1Cl
[H]C1=C([H])C(=C([H])C([H])=C1Cl)C1=C(C(=NN1C1=C([H])C([H])=C(Cl)C([H])=C1Cl)C1=NC(C(=O)N1C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])C(=C([H])C([H])=C1Cl)C1=C(C(=NN1C1=C([H])C([H])=C(Cl)C([H])=C1Cl)C1=NC(C(=O)N1C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])[H]
[H]OC1=C([H])C(=C([H])C2=C1[C@]1([H])C([H])([H])C(C([H])=O)=C([H])C([H])([H])[C@@]1([H])C(O2)(C([H])([H])[H])C([H])([H])[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]C1=C(OP(=O)(OC([H])([H])C([H])([H])[H])OC([H])([H])C([H])([H])[H])C2=C(OC(C([H])([H])[H])(C([H])([H])[H])[C@]3([H])C([H])([H])C([H])=C(C([H])([H])[H])C([H])([H])[C@@]23[H])C([H])=C1C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]OC1=C([H])C(=C([H])C2=C1[C@]1([H])C([H])([H])C(=C([H])[H])C([H])([H])C([H])([H])[C@@]1([H])C(O2)(C([H])([H])[H])C([H])([H])[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]OC1=C([H])C(=C([H])C(O[H])=C1C1=C([H])C(=C([H])C(=C1[H])C([H])([H])[H])C([H])([H])[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]OC1=C([H])C(=C([H])C(O[H])=C1[C@]1([H])C([H])=C(C([H])([H])[H])[C@]2([H])C([H])([H])[C@@]1([H])C2(C([H])([H])[H])C([H])([H])[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]C1=C([H])C2=C(OC(C([H])([H])[H])(C([H])([H])[H])[C@]3([H])C([H])([H])C([H])=C(C([H])([H])[H])C([H])([H])[C@@]23[H])C([H])=C1C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]C1=C(OC([H])([H])[H])C2=C(OC(C([H])([H])[H])(C([H])([H])[H])[C@]3([H])C([H])([H])C([H])=C(C([H])([H])[H])C([H])([H])[C@@]23[H])C([H])=C1C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]C([H])=C1C([H])([H])C([H])([H])[C@]2([H])[C@]([H])(C3=C(OC2(C([H])([H])[H])C([H])([H])[H])C([H])=C(C([H])=C3OC([H])([H])[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C1([H])[H]
[H]C1=C(OC([H])([H])[H])C2=C(OC(C([H])([H])[H])(C([H])([H])[H])[C@]3([H])C([H])([H])C([H])([H])C(=O)C([H])([H])[C@@]23[H])C([H])=C1C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]OC1=C([H])C(=C([H])C2=C1[C@]1([H])C([H])([H])C(=O)C([H])([H])C([H])([H])[C@@]1([H])C(O2)(C([H])([H])[H])C([H])([H])[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]C1=C(OC([H])([H])[H])C(=C(OC([H])([H])[H])C([H])=C1C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C1=C([H])C(=C([H])C(=C1[H])C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)C1=NN(C(=C1C([H])([H])[H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])C1=C(Br)C([H])=C([H])C([H])=C1[H])C1(C#N)C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]C1=C([H])N2C(=NC(=C2C([H])=C1[H])C([H])([H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C(=O)C1=C([H])C([H])=C([H])C(Cl)=C1Cl
[H]C1=C([H])N2C(=NC(=C2C([H])=C1[H])C([H])([H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C(=O)C1=C([H])C([H])=C([H])C(F)=C1C(F)(F)F
[H]C1=C([H])N2C(=NC(=C2C([H])=C1[H])C([H])([H])N1C([H])([H])C([H])([H])C(F)(F)C([H])([H])C1([H])[H])C(=O)C1=C([H])C([H])=C([H])C(Cl)=C1Cl
[H]N(C(=O)C1=NC(=C2C([H])=C([H])C([H])=C([H])N12)C([H])([H])N1C([H])([H])C([H])([H])C(F)(F)C([H])([H])C1([H])[H])C1=NC(=C([H])C([H])=C1[H])C(F)(F)F
[H]N(C(=O)C1=NC(=C2C([H])=C([H])C([H])=C([H])N12)C([H])([H])N1C([H])([H])C([H])([H])S(=O)(=O)C([H])([H])C1([H])[H])C1=NC(=C([H])C([H])=C1[H])C(F)(F)F
[H]OC([H])([H])C1(C([H])([H])N([H])C(=O)C2=C3C([H])=C([H])C([H])=C([H])N3C(=N2)C([H])([H])N2C([H])([H])C([H])([H])C(F)(F)C([H])([H])C2([H])[H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(C(=O)C1=C2C([H])=C([H])C([H])=C([H])N2C(=N1)C1([H])C([H])([H])C1([H])[H])C([H])(C1([H])C([H])([H])C1([H])[H])C1([H])C([H])([H])C1([H])[H]
[H]N(C(=O)C1=C2C([H])=C([H])C([H])=C([H])N2C(=N1)C1([H])C([H])([H])C1([H])[H])C([H])([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)C1=C2C([H])=C([H])C([H])=C([H])N2C(=N1)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])[C@]([H])(C1=NC([H])=C([H])C([H])=C1[H])C(F)(F)F
[H]OC([H])([H])C1(C([H])([H])N([H])C(=O)C2=C3C([H])=C([H])C([H])=C([H])N3C(=N2)N2C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(C(=O)C1=NC(N2C([H])([H])C([H])([H])C(F)(F)C2([H])[H])=C2C([H])=NC([H])=C([H])N12)[C@]([H])(C1=C([H])C([H])=NC([H])=C1[H])C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]N(C(=O)C1=NC(N2C([H])([H])C([H])([H])C(F)(F)C([H])([H])C2([H])[H])=C2C([H])=NC([H])=C([H])N12)[C@]([H])(C([H])([H])[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)C1=NC(N2C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])=C2C([H])=NC([H])=C([H])N12)[C@]([H])(C1=NC([H])=C([H])C([H])=C1[H])C(F)(F)F
[H]N(C(=O)C1=NC(N2C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])=C2C([H])=NC([H])=C([H])N12)[C@]([H])(C1=C([H])N=C([H])C([H])=C1[H])C(F)(F)F
[H]N(C(=O)N1C([H])([H])C([H])([H])N(C(=O)C2([H])C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])C([H])([H])C([H])([H])C1([H])[H])C1=NC([H])=C(S1)C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)N1C([H])([H])C([H])([H])N(C(=O)C2([H])C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])C([H])([H])C([H])([H])C1([H])[H])C1=NC([H])=C(S1)C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)N1C([H])([H])C([H])([H])N(C(=O)C2([H])C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])C([H])([H])C([H])([H])C1([H])[H])C1=NC(=C([H])S1)C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)N1C([H])([H])C([H])([H])N(C(=O)C2([H])C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])C([H])([H])C([H])([H])C1([H])[H])C1=NC(=C([H])S1)C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)N1C([H])([H])C([H])([H])N(C(=O)[C@@]2([H])C([H])([H])OC([H])([H])C([H])([H])C2([H])[H])C([H])([H])C([H])([H])C1([H])[H])C1=NOC(=C1[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)N1C([H])([H])C([H])([H])N(C(=O)[C@]2([H])OC([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C([H])([H])C1([H])[H])C1=NOC(=C1[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)N1C([H])([H])C([H])([H])N(C(=O)[C@]2([H])OC([H])([H])C([H])([H])C2([H])[H])C([H])([H])C([H])([H])C1([H])[H])C1=NOC(=C1[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)N1C([H])([H])C([H])([H])N(C(=O)[C@]2([H])C([H])([H])OC([H])([H])C2([H])[H])C([H])([H])C([H])([H])C1([H])[H])C1=NOC(=C1[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]O[C@@]1([H])C([H])([H])C([H])([H])[C@@]([H])(C(=O)N2C([H])([H])C([H])([H])N(C(=O)N([H])C3=NOC(=C3[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]N(C(=O)N1C([H])([H])C([H])([H])N(C(=O)C2([H])C([H])([H])C([H])([H])N(C(=O)C([H])([H])[H])C([H])([H])C2([H])[H])C([H])([H])C([H])([H])C1([H])[H])C1=NOC(=C1[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)N1C([H])([H])C([H])([H])N(C(=O)C2([H])C([H])([H])C([H])([H])N(C([H])([H])C2([H])[H])S(=O)(=O)C([H])([H])[H])C([H])([H])C([H])([H])C1([H])[H])C1=NOC(=C1[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)N1C([H])([H])C([H])([H])N(C(=O)C([H])([H])N2C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])C([H])([H])C([H])([H])C1([H])[H])C1=NOC(=C1[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)N1C([H])([H])C([H])([H])N(C(=O)C([H])([H])N2C([H])([H])C([H])([H])S(=O)(=O)C([H])([H])C2([H])[H])C([H])([H])C([H])([H])C1([H])[H])C1=NOC(=C1[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)N1C([H])([H])C([H])([H])N(C(=O)N2C([H])([H])C([H])([H])S(=O)(=O)C([H])([H])C2([H])[H])C([H])([H])C([H])([H])C1([H])[H])C1=NOC(=C1[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)N1C([H])([H])C([H])([H])N(C(=O)N2C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])C([H])([H])C([H])([H])C1([H])[H])C1=NOC(=C1[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)N1C([H])([H])C([H])([H])N(C(=O)N2C([H])([H])C([H])([H])N(C([H])([H])C2([H])[H])S(=O)(=O)C([H])([H])[H])C([H])([H])C([H])([H])C1([H])[H])C1=NOC(=C1[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)N1C([H])([H])C([H])([H])N(C(=O)N2C([H])([H])C([H])([H])C([H])(C([H])([H])C2([H])[H])S(=O)(=O)C([H])([H])[H])C([H])([H])C([H])([H])C1([H])[H])C1=NOC(=C1[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)N1C([H])([H])C([H])([H])N(C(=O)N([H])C2([H])C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])C([H])([H])C([H])([H])C1([H])[H])C1=NOC(=C1[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)N1C([H])([H])C([H])([H])N(C(=O)C([H])([H])C([H])([H])C2([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]N(C(=O)N1C([H])([H])C([H])([H])N(C(=O)C([H])([H])C([H])([H])C2([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])[H]
[H]N(C(=O)N1C([H])([H])C([H])([H])N(C(=O)C([H])([H])C([H])([H])C2([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)N1C([H])([H])C([H])([H])N(C(=O)C2([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)N1C([H])([H])C([H])([H])N(C(=O)C([H])([H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)N1C([H])([H])C([H])([H])N(C(=O)C2=C([H])C([H])=C(Cl)C([H])=C2[H])C([H])([H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)N1C([H])([H])C([H])([H])N(C(=O)C2=C([H])C(Cl)=C([H])C(Cl)=C2[H])C([H])([H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)N1C([H])([H])C([H])([H])N(C(=O)C2=C([H])C(Cl)=C([H])C([H])=C2Cl)C([H])([H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)N1C([H])([H])C([H])([H])N(C(=O)C2=C([H])C([H])=C(C([H])=C2[H])C(F)(F)F)C([H])([H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)N1C([H])([H])C([H])([H])N(C(=O)C2=C([H])C([H])=C(C([H])=C2[H])N(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)N1C([H])([H])C([H])([H])N(C(=O)C2([H])C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])C([H])([H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)N1C([H])([H])C([H])([H])N(C(=O)C2([H])C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])C([H])([H])C([H])([H])C1([H])[H])C1=NOC(=C1[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)N1C([H])([H])C([H])([H])N(C(=O)C2([H])C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])C([H])([H])C([H])([H])C1([H])[H])C1=C([H])C(=NO1)C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)N1C([H])([H])C([H])([H])N(C(=O)C2([H])C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])C([H])([H])C([H])([H])C1([H])[H])C1=NOC(=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC(=O)C1=C([H])C(=C([H])C2=C([H])C([H])=C([H])C([H])=C12)N1C([H])([H])C([H])([H])N(C(=O)C2=NC(C3=C([H])C([H])=C(C([H])=C3F)C([H])([H])[H])=C(C([H])=N2)C2=C([H])C([H])=C(OC([H])([H])[H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]OC(=O)C1=C([H])C(=C([H])C2=C([H])C([H])=C([H])C([H])=C12)N1C([H])([H])C([H])([H])N(C(=O)C2=NC(C3=C([H])C([H])=C(C([H])=C3F)C([H])([H])[H])=C(C([H])=N2)C2=C([H])C3=C(OC([H])([H])C([H])([H])O3)C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N([H])C(=O)C([H])([H])C([H])([H])N1C([H])=C(C(=O)C2([H])C(C([H])([H])[H])(C([H])([H])[H])C2(C([H])([H])[H])C([H])([H])[H])C2=C1C([H])=C([H])C([H])=C2[H]
[H]OC(=O)C([H])([H])C([H])([H])N1C([H])=C(C(=O)C2([H])C(C([H])([H])[H])(C([H])([H])[H])C2(C([H])([H])[H])C([H])([H])[H])C2=C1C([H])=C([H])C([H])=C2[H]
[H]C1=C(C(=O)C2([H])C(C([H])([H])[H])(C([H])([H])[H])C2(C([H])([H])[H])C([H])([H])[H])C2=C(C([H])=C([H])C([H])=C2[H])N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])SC([H])([H])[H]
[H]C1=C(C(=O)C2([H])C(C([H])([H])[H])(C([H])([H])[H])C2(C([H])([H])[H])C([H])([H])[H])C2=C(C([H])=C([H])C([H])=C2[H])N1C([H])([H])C([H])([H])C([H])([H])OC([H])([H])[H]
[H]C1=C(C(=O)C2([H])C(C([H])([H])[H])(C([H])([H])[H])C2(C([H])([H])[H])C([H])([H])[H])C2=C(C([H])=C([H])C([H])=C2[H])N1C([H])([H])C([H])([H])OC([H])([H])[H]
[H]OC([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N1C([H])=C(C(=O)C2([H])C(C([H])([H])[H])(C([H])([H])[H])C2(C([H])([H])[H])C([H])([H])[H])C2=C1C([H])=C([H])C([H])=C2[H]
[H]OC([H])([H])C([H])([H])C([H])([H])C([H])([H])N1C([H])=C(C(=O)C2([H])C(C([H])([H])[H])(C([H])([H])[H])C2(C([H])([H])[H])C([H])([H])[H])C2=C1C([H])=C([H])C([H])=C2[H]
[H]OC([H])([H])C([H])([H])C([H])([H])N1C([H])=C(C(=O)C2([H])C(C([H])([H])[H])(C([H])([H])[H])C2(C([H])([H])[H])C([H])([H])[H])C2=C1C([H])=C([H])C([H])=C2[H]
[H]OC([H])([H])C([H])([H])N1C([H])=C(C(=O)C2([H])C(C([H])([H])[H])(C([H])([H])[H])C2(C([H])([H])[H])C([H])([H])[H])C2=C1C([H])=C([H])C([H])=C2[H]
[H]C1=C(C(=O)C2([H])C(C([H])([H])[H])(C([H])([H])[H])C2(C([H])([H])[H])C([H])([H])[H])C2=C(C([H])=C([H])C([H])=C2[H])N1C([H])([H])C([H])([H])C([H])([H])C(F)(F)F
[H]C1=C(C(=O)C2([H])C(C([H])([H])[H])(C([H])([H])[H])C2(C([H])([H])[H])C([H])([H])[H])C2=C(C([H])=C([H])C([H])=C2[H])N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]C1=C(C(=O)C2([H])C(C([H])([H])[H])(C([H])([H])[H])C2(C([H])([H])[H])C([H])([H])[H])C2=C(C([H])=C([H])C([H])=C2[H])N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]C1=C(C(=O)C2([H])C(C([H])([H])[H])(C([H])([H])[H])C2(C([H])([H])[H])C([H])([H])[H])C2=C(C([H])=C([H])C([H])=C2[H])N1C([H])([H])C([H])([H])C([H])([H])[H]
[H]C1=C(C(=O)C2([H])C(C([H])([H])[H])(C([H])([H])[H])C2(C([H])([H])[H])C([H])([H])[H])C2=C(C([H])=C([H])C([H])=C2[H])N1C([H])([H])C([H])([H])N1C(=O)C([H])([H])C([H])([H])C1=O
[H]C1=C(C(=O)C2([H])C(C([H])([H])[H])(C([H])([H])[H])C2(C([H])([H])[H])C([H])([H])[H])C2=C(C([H])=C([H])C([H])=C2[H])N1C([H])([H])C([H])([H])N1C(=O)C([H])([H])C([H])([H])C1([H])[H]
[H]C1=C(C(=O)C2([H])C(C([H])([H])[H])(C([H])([H])[H])C2(C([H])([H])[H])C([H])([H])[H])C2=C(C([H])=C([H])C([H])=C2[H])N1C([H])([H])C([H])([H])N1C(=O)OC([H])([H])C1([H])[H]
[H]C1=C(C(=O)C2([H])C(C([H])([H])[H])(C([H])([H])[H])C2(C([H])([H])[H])C([H])([H])[H])C2=C(C([H])=C([H])C([H])=C2[H])N1C([H])([H])C1([H])OC([H])([H])C([H])([H])O1
[H]C1=C(C(=O)C2([H])C(C([H])([H])[H])(C([H])([H])[H])C2(C([H])([H])[H])C([H])([H])[H])C2=C(C([H])=C([H])C([H])=C2[H])N1C(=O)C([H])([H])C1([H])C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]C1=C(C(=O)C2([H])C(C([H])([H])[H])(C([H])([H])[H])C2(C([H])([H])[H])C([H])([H])[H])C2=C(C([H])=C([H])C([H])=C2[H])N1C([H])([H])[C@]1([H])OC([H])([H])C([H])([H])C1([H])[H]
[H]C1=C(C(=O)C2([H])C(C([H])([H])[H])(C([H])([H])[H])C2(C([H])([H])[H])C([H])([H])[H])C2=C(C([H])=C([H])C([H])=C2[H])N1C([H])([H])C([H])([H])C1([H])C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]C1=C(C(=O)[C@]23C([H])([H])[C@]4([H])C([H])([H])[C@@]2([H])C([H])([H])[C@]([H])(C3([H])[H])C4([H])[H])C2=C(C([H])=C([H])C([H])=C2[H])N1C([H])([H])C1([H])C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]C1=C(C(=O)[C@]2([H])C([H])([H])[C@]22C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C2=C(C([H])=C([H])C([H])=C2[H])N1C([H])([H])C1([H])C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]C1=C(C(=O)[C@@]23O[C@]4([H])C([H])([H])[C@@]([H])(C([H])([H])[C@@]([H])(C4([H])[H])C2([H])[H])C3([H])[H])C2=C(C([H])=C([H])C([H])=C2[H])N1C([H])([H])C1([H])C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]C1=C(C(=O)C2([H])C(C([H])([H])[H])(C([H])([H])[H])C2(C([H])([H])[H])C([H])([H])[H])C2=C(C([H])=C([H])C([H])=C2[H])N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H]
[H]N([H])C([H])([H])C([H])([H])N1C([H])=C(C(=O)C2([H])C(C([H])([H])[H])(C([H])([H])[H])C2(C([H])([H])[H])C([H])([H])[H])C2=C1C([H])=C([H])C([H])=C2[H]
[H]C1=C(C(=O)C2([H])C(C([H])([H])[H])(C([H])([H])[H])C2(C([H])([H])[H])C([H])([H])[H])C2=C(C([H])=C([H])C([H])=C2[H])N1C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]C1=C(C(=O)C2([H])C(C([H])([H])[H])(C([H])([H])[H])C2(C([H])([H])[H])C([H])([H])[H])C2=C(C([H])=C([H])C([H])=C2[H])N1C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]C1=C(C(=O)C2([H])C(C([H])([H])[H])(C([H])([H])[H])C2(C([H])([H])[H])C([H])([H])[H])C2=C(C([H])=C([H])C([H])=C2[H])N1C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N1C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])N2C([H])=C(C(=O)C3([H])C(C([H])([H])[H])(C([H])([H])[H])C3(C([H])([H])[H])C([H])([H])[H])C3=C2C([H])=C([H])C([H])=C3[H])C([H])([H])C1([H])[H]
[H]C1=C(C(=O)C2([H])C(C([H])([H])[H])(C([H])([H])[H])C2(C([H])([H])[H])C([H])([H])[H])C2=C(C([H])=C([H])C([H])=C2[H])N1C([H])([H])[C@@]1([H])N(C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]C1=C(C(=O)C2([H])C(C([H])([H])[H])(C([H])([H])[H])C2(C([H])([H])[H])C([H])([H])[H])C2=C(C([H])=C([H])C([H])=C2[H])N1C([H])([H])C([H])([H])C(=O)OC([H])([H])[H]
[H]C1=C(C(=O)C2([H])C(C([H])([H])[H])(C([H])([H])[H])C2(C([H])([H])[H])C([H])([H])[H])C2=C(C([H])=C([H])C([H])=C2[H])N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C(=O)C([H])([H])[H]
[H]C1=C(C(=O)C2([H])C(C([H])([H])[H])(C([H])([H])[H])C2(C([H])([H])[H])C([H])([H])[H])C2=C(C([H])=C([H])C([H])=C2[H])N1C([H])([H])C1=C([H])C([H])=C([H])N=C1[H]
[H]C1=C(C(=O)C2([H])C(C([H])([H])[H])(C([H])([H])[H])C2(C([H])([H])[H])C([H])([H])[H])C2=C(C([H])=C([H])C([H])=C2[H])N1C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C1=C(C(=O)C2([H])C(C([H])([H])[H])(C([H])([H])[H])C2(C([H])([H])[H])C([H])([H])[H])C2=C(C([H])=C([H])C([H])=C2[H])N1C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]C1=C(C(=O)C2([H])C(C([H])([H])[H])(C([H])([H])[H])C2(C([H])([H])[H])C([H])([H])[H])C2=C(C([H])=C([H])C([H])=C2[H])N1C([H])([H])C([H])([H])[C@@]1([H])N(C([H])([H])[H])C([H])([H])C([H])([H])C1([H])[H]
[H]C1=C(C(=O)C2([H])C(C([H])([H])[H])(C([H])([H])[H])C2(C([H])([H])[H])C([H])([H])[H])C2=C(C([H])=C([H])C([H])=C2[H])N1C([H])([H])C([H])([H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H]
[H]C1=C(C(=O)C2([H])C(C([H])([H])[H])(C([H])([H])[H])C2(C([H])([H])[H])C([H])([H])[H])C2=C(C([H])=C([H])C([H])=C2[H])N1C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H]
[H]C1=C(C(=O)[C@@]2(C([H])([H])[H])C([H])([H])C2(Cl)Cl)C2=C(C([H])=C([H])C([H])=C2[H])N1C([H])([H])C1([H])C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]C1=C(C(=O)[C@@]2(C([H])([H])[H])C([H])([H])C(F)(F)C2(F)F)C2=C(C([H])=C([H])C([H])=C2[H])N1C([H])([H])C1([H])C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]C1=C(C(=O)C2([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C2=C(C([H])=C([H])C([H])=C2[H])N1C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]C1=C(C(=O)C2([H])C([H])([H])C([H])([H])C2([H])[H])C2=C(C([H])=C([H])C([H])=C2[H])N1C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]C1=C(C(=O)[C@]2(C([H])([H])[H])C([H])([H])C2(Cl)Cl)C2=C(C([H])=C([H])C([H])=C2[H])N1C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]C1=C(C(=O)[C@@]2([H])C([H])([H])C(F)(F)C2(F)F)C2=C(C([H])=C([H])C([H])=C2[H])N1C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]C1=C(C(=O)[C@]23C([H])([H])[C@]4([H])C([H])([H])[C@@]2([H])C([H])([H])[C@]([H])(C3([H])[H])C4([H])[H])C2=C(C([H])=C([H])C([H])=C2[H])N1C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]C1=C(C(=O)C2([H])C(C([H])([H])[H])(C([H])([H])[H])C2(C([H])([H])[H])C([H])([H])[H])C2=C(C([H])=C([H])C([H])=C2[H])N1C([H])([H])[C@]1([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]N1C([H])([H])C([H])([H])C([H])(C([H])([H])C([H])([H])N2C([H])=C(C(=O)C3([H])C(C([H])([H])[H])(C([H])([H])[H])C3(C([H])([H])[H])C([H])([H])[H])C3=C2C([H])=C([H])C([H])=C3[H])C([H])([H])C1([H])[H]
[H]N(C(=O)C1=NN(C(N2C(=C([H])C([H])=C2C([H])([H])[H])C([H])([H])[H])=C1C([H])([H])[H])C1=C([H])C([H])=C(Cl)C(Cl)=C1[H])[C@]12C([H])([H])[C@@]3([H])C([H])([H])[C@]([H])(C([H])([H])[C@]([H])(C3([H])[H])C1([H])[H])C2([H])[H]
[H]N(C(=O)C1=NN(C(N2C(=C([H])C([H])=C2C([H])([H])[H])C([H])([H])[H])=C1C([H])([H])[H])C1=C([H])C([H])=C(Cl)C(Cl)=C1[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(C(=O)C1=NN(C(N2C(=C([H])C([H])=C2C([H])([H])[H])C([H])([H])[H])=C1C([H])([H])[H])C1=C([H])C([H])=C(Cl)C(Cl)=C1[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(C(=O)C1=NN(C(N2C(=C([H])C([H])=C2C([H])([H])[H])C([H])([H])[H])=C1C([H])([H])[H])C1=C([H])C([H])=C(Cl)C(Cl)=C1[H])C([H])([H])C([H])([H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]N(C(=O)C1=NN(C(N2C(=C([H])C([H])=C2C([H])([H])[H])C([H])([H])[H])=C1C([H])([H])[H])C1=C([H])C([H])=C(Cl)C(Cl)=C1[H])C([H])([H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]N(C(=O)C1=NN(C(N2C(=C([H])C([H])=C2C([H])([H])[H])C([H])([H])[H])=C1C([H])([H])[H])C1=C([H])C([H])=C(Cl)C(Cl)=C1[H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]N(C(=O)C1=NN(C(N2C([H])=C([H])C([H])=C2[H])=C1C([H])([H])[H])C1=C([H])C([H])=C(Cl)C(Cl)=C1[H])[C@@]([H])(C([H])([H])[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(C(=O)C1=NN(C(N2C([H])=C([H])C([H])=C2[H])=C1C([H])([H])[H])C1=C([H])C([H])=C(Cl)C(Cl)=C1[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(C(=O)C1=NN(C(N2C([H])=C([H])C([H])=C2[H])=C1C([H])([H])[H])C1=C([H])C([H])=C(Cl)C(Cl)=C1[H])C([H])([H])C([H])([H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]N(C(=O)C1=NN(C(N2C([H])=C([H])C([H])=C2[H])=C1C([H])([H])[H])C1=C([H])C([H])=C(Cl)C(Cl)=C1[H])C([H])([H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]N(C(=O)C1=NN(C(N2C([H])=C([H])C([H])=C2[H])=C1C([H])([H])[H])C1=C([H])C([H])=C(Cl)C(Cl)=C1[H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]N(C(=O)C1=NN(C(N2C(=C([H])C([H])=C2C([H])([H])[H])C([H])([H])[H])=C1C([H])([H])[H])C1=C([H])C([H])=C(Cl)C([H])=C1Cl)C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(C(=O)C1=NN(C(N2C(=C([H])C([H])=C2C([H])([H])[H])C([H])([H])[H])=C1C([H])([H])[H])C1=C([H])C([H])=C(Cl)C([H])=C1Cl)C1([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(C(=O)C1=NN(C(N2C(=C([H])C([H])=C2C([H])([H])[H])C([H])([H])[H])=C1C([H])([H])[H])C1=C([H])C([H])=C(Cl)C([H])=C1Cl)C([H])([H])C([H])([H])C1=C([H])C([H])=C(Cl)C([H])=C1Cl
[H]N(C(=O)C1=NN(C(N2C(=C([H])C([H])=C2C([H])([H])[H])C([H])([H])[H])=C1C([H])([H])[H])C1=C([H])C([H])=C(Cl)C([H])=C1Cl)C([H])([H])C([H])([H])C1=C([H])C([H])=C(OC([H])([H])[H])C(Cl)=C1[H]
[H]N(C(=O)C1=NN(C(N2C(=C([H])C([H])=C2C([H])([H])[H])C([H])([H])[H])=C1C([H])([H])[H])C1=C([H])C([H])=C(F)C([H])=C1F)C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(C(=O)C1=NN(C(N2C(=C([H])C([H])=C2C([H])([H])[H])C([H])([H])[H])=C1C([H])([H])[H])C1=C([H])C([H])=C(F)C([H])=C1F)C1([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(C(=O)C1=NN(C(N2C(=C([H])C([H])=C2C([H])([H])[H])C([H])([H])[H])=C1C([H])([H])[H])C1=C([H])C([H])=C(F)C([H])=C1F)C([H])([H])C([H])([H])C1=C([H])C([H])=C(Cl)C([H])=C1Cl
[H]N(C(=O)C1=NN(C(N2C(=C([H])C([H])=C2C([H])([H])[H])C([H])([H])[H])=C1C([H])([H])[H])C1=C([H])C([H])=C(F)C([H])=C1F)C([H])([H])C([H])([H])C1=C([H])C([H])=C(OC([H])([H])[H])C(Cl)=C1[H]
[H]N(C(=O)C1=NN(C(N2C(=C([H])C([H])=C2C([H])([H])[H])C([H])([H])[H])=C1C([H])([H])[H])C1=C([H])C([H])=C(F)C([H])=C1F)C([H])([H])C([H])([H])C1=C([H])C([H])=C(Cl)C(Cl)=C1[H]
[H]N(C(=O)C1=NN(C(N2C(=C([H])C([H])=C2C([H])([H])[H])C([H])([H])[H])=C1C([H])([H])[H])C1=C([H])C([H])=C(F)C([H])=C1F)C([H])([H])C([H])([H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]N(C(=O)C1=NN(C(N2C(=C([H])C([H])=C2C([H])([H])[H])C([H])([H])[H])=C1C([H])([H])[H])C1=C([H])C([H])=C(F)C([H])=C1F)C([H])([H])C1=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C(OC([H])([H])[H])=C1Br
[H]N(C(=O)C1=NN(C(N2C(=C([H])C([H])=C2C([H])([H])[H])C([H])([H])[H])=C1C([H])([H])[H])C1=C([H])C([H])=C(F)C([H])=C1F)C([H])([H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]N(C(=O)C1=NN(C(N2C(=C([H])C([H])=C2C([H])([H])[H])C([H])([H])[H])=C1C([H])([H])[H])C1=C([H])C([H])=C(F)C([H])=C1F)C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]N(C(=O)C1=NN(C(N2C([H])=C([H])C([H])=C2[H])=C1C([H])([H])[H])C1=C([H])C([H])=C(F)C([H])=C1F)C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(C(=O)C1=NN(C(N2C([H])=C([H])C([H])=C2[H])=C1C([H])([H])[H])C1=C([H])C([H])=C(F)C([H])=C1F)C1([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(C(=O)C1=NN(C(N2C([H])=C([H])C([H])=C2[H])=C1C([H])([H])[H])C1=C([H])C([H])=C(F)C([H])=C1F)C([H])([H])C([H])([H])C1=C([H])C([H])=C(Cl)C([H])=C1Cl
[H]N(C(=O)C1=NN(C(N2C([H])=C([H])C([H])=C2[H])=C1C([H])([H])[H])C1=C([H])C([H])=C(F)C([H])=C1F)C([H])([H])C([H])([H])C1=C([H])C([H])=C(OC([H])([H])[H])C(Cl)=C1[H]
[H]N(C(=O)C1=NN(C(N2C([H])=C([H])C([H])=C2[H])=C1C([H])([H])[H])C1=C([H])C([H])=C(F)C([H])=C1F)C([H])([H])C([H])([H])C1=C([H])C([H])=C(Cl)C(Cl)=C1[H]
[H]N(C(=O)C1=NN(C(N2C([H])=C([H])C([H])=C2[H])=C1C([H])([H])[H])C1=C([H])C([H])=C(F)C([H])=C1F)C([H])([H])C([H])([H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]N(C(=O)C1=NN(C(N2C([H])=C([H])C([H])=C2[H])=C1C([H])([H])[H])C1=C([H])C([H])=C(F)C([H])=C1F)C([H])([H])C1=C(Br)C(OC([H])([H])[H])=C(OC([H])([H])[H])C(OC([H])([H])[H])=C1[H]
[H]N(C(=O)C1=NN(C(N2C([H])=C([H])C([H])=C2[H])=C1C([H])([H])[H])C1=C([H])C([H])=C(F)C([H])=C1F)C([H])([H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]N(C(=O)C1=NN(C(N2C([H])=C([H])C([H])=C2[H])=C1C([H])([H])[H])C1=C(F)C([H])=C(F)C([H])=C1[H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]N(C(=O)C1=NN(C(N2C(=C([H])C([H])=C2C([H])([H])[H])C([H])([H])[H])=C1C([H])([H])[H])C1=C([H])C([H])=C(Cl)C(Cl)=C1[H])[C@]([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]N(C(=O)C1=NN(C(N2C(=C([H])C([H])=C2C([H])([H])[H])C([H])([H])[H])=C1C([H])([H])[H])C1=C([H])C([H])=C(Cl)C(Cl)=C1[H])[C@@]([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H]
[H]OC([H])([H])C(=O)N([H])C1=C(OC2=NC(C3=C([H])C([H])=C([H])C([H])=C3Cl)=C(C([H])=C12)C1=C([H])C([H])=C(Cl)C([H])=C1[H])C(=O)C(O[H])(C([H])([H])[H])C([H])([H])[H]
[H]O[C@]([H])(C(=O)N([H])[C@@]1([H])C2=C([H])C(C3=C([H])C([H])=C(Cl)C([H])=C3[H])=C(N=C2OC(C([H])([H])[H])(C([H])([H])[H])C1([H])[H])C1=C([H])C([H])=C(Cl)C([H])=C1Cl)C([H])([H])[H]
[H]OC(C(=O)N([H])[C@@]1([H])C2=C([H])C(C3=C([H])C([H])=C(Cl)C([H])=C3[H])=C(N=C2OC(C([H])([H])[H])(C([H])([H])[H])C1([H])[H])C1=C([H])C([H])=C(Cl)C([H])=C1Cl)(C([H])([H])[H])C([H])([H])[H]
[H]OC1(C(=O)N([H])[C@@]2([H])C3=C([H])C(C4=C([H])C([H])=C(Cl)C([H])=C4[H])=C(N=C3OC(C([H])([H])[H])(C([H])([H])[H])C2([H])[H])C2=C([H])C([H])=C(Cl)C([H])=C2Cl)C([H])([H])C1([H])[H]
[H]O[C@]([H])(C(=O)N([H])[C@@]1([H])C([H])([H])C(O[C@]2([H])N([H])[C@@]([H])([C@@]3([H])C([H])([H])C([H])([H])[C@@]([H])(Cl)C([H])([H])[C@@]3([H])C([H])([H])[H])[C@@]([H])(C([H])([H])[C@]12[H])[C@@]1([H])C([H])([H])C([H])([H])[C@]([H])(Cl)C([H])([H])C1([H])[H])(C([H])([H])[H])C([H])([H])[H])C(F)(F)F
[H]O[C@](C(=O)N([H])[C@@]1([H])C2=C([H])C(C3=C([H])C([H])=C(Cl)C([H])=C3[H])=C(N=C2OC(C([H])([H])[H])(C([H])([H])[H])C1([H])[H])C1=C([H])C([H])=C(Cl)C([H])=C1Cl)(C([H])([H])[H])C(F)(F)F
[H]O[C@@]([H])(C([H])([H])C(=O)N([H])[C@@]1([H])C2=C([H])C(C3=C([H])C([H])=C(Cl)C([H])=C3[H])=C(N=C2OC(C([H])([H])[H])(C([H])([H])[H])C1([H])[H])C1=C([H])C([H])=C(Cl)C([H])=C1Cl)C(F)(F)F
[H]OC([H])([H])C(F)(F)C(=O)N([H])[C@@]1([H])C2=C([H])C(C3=C([H])C([H])=C(Cl)C([H])=C3[H])=C(N=C2OC(C([H])([H])[H])(C([H])([H])[H])C1([H])[H])C1=C([H])C([H])=C(Cl)C([H])=C1Cl
[H]OC1=C([H])C([H])=C([H])C([H])=C1C(=O)N([H])[C@@]1([H])C2=C([H])C(C3=C([H])C([H])=C(Cl)C([H])=C3[H])=C(N=C2OC(C([H])([H])[H])(C([H])([H])[H])C1([H])[H])C1=C([H])C([H])=C(Cl)C([H])=C1Cl
[H]N([H])C1=C([H])C([H])=C([H])C([H])=C1C(=O)N([H])[C@@]1([H])C2=C([H])C(=C(N=C2OC(C([H])([H])[H])(C([H])([H])[H])C1([H])[H])C1=C([H])C([H])=C(Cl)C([H])=C1Cl)C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]N(C(=O)C1=NN([H])C(=C1[H])C([H])([H])C([H])([H])[H])[C@@]1([H])C2=C([H])C(=C(N=C2OC(C([H])([H])[H])(C([H])([H])[H])C1([H])[H])C1=C([H])C([H])=C(Cl)C([H])=C1Cl)C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]N(C(=O)C1=NN([H])C([H])=C1C([H])([H])[H])[C@@]1([H])C2=C([H])C(=C(N=C2OC(C([H])([H])[H])(C([H])([H])[H])C1([H])[H])C1=C([H])C([H])=C(Cl)C([H])=C1Cl)C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]N(C(=O)C1=NN([H])C(=C1C([H])([H])[H])C([H])([H])[H])[C@@]1([H])C2=C([H])C(=C(N=C2OC(C([H])([H])[H])(C([H])([H])[H])C1([H])[H])C1=C([H])C([H])=C(Cl)C([H])=C1Cl)C1=C([H])C([H])=C(Cl)C([H])=C1[H]
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[H]OC([H])([H])C1(C([H])([H])N([H])S(=O)(=O)C(F)(F)F)C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])S(=O)(=O)C1=C(C([H])=C(Cl)C([H])=C1[H])S(=O)(=O)C1=C([H])C([H])=C([H])C([H])=C1F
[H]O[C@@]([H])(C([H])([H])[H])C1(C([H])([H])N([H])S(=O)(=O)C(F)(F)F)C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])S(=O)(=O)C1=C(C([H])=C(Cl)C([H])=C1[H])S(=O)(=O)C1=C([H])C([H])=C([H])C([H])=C1F
[H]N(C([H])([H])C1(F)C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])S(=O)(=O)C1=C(C([H])=C(Cl)C([H])=C1[H])S(=O)(=O)C1=C([H])C([H])=C([H])C([H])=C1F)S(=O)(=O)C(F)(F)F
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[H]C([H])=C([H])C([H])([H])OC(=O)N([H])C([H])([H])C1(C([H])([H])N([H])S(=O)(=O)C(F)(F)F)C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])S(=O)(=O)C1=C(C([H])=C(Cl)C([H])=C1[H])S(=O)(=O)C1=C([H])C([H])=C([H])C([H])=C1F
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[H]N(C([H])([H])C1(C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])S(=O)(=O)C1=C(C([H])=C(Cl)C([H])=C1[H])S(=O)(=O)C1=C([H])C([H])=C([H])C([H])=C1F)S(=O)(=O)C(F)(F)F
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[H]N(C(=O)C1=C2C(N([H])C([H])=C2C([H])([H])[H])=C(N=C1[H])N([H])C1=C([H])C([H])=C([H])C(Cl)=C1[H])C([H])([H])C1([H])C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
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[H]N(C(=O)C1=C2C(N([H])C([H])=C2C([H])([H])[H])=C(N=C1[H])N([H])C1=C([H])C([H])=C([H])C(Cl)=C1[H])C([H])([H])C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]N(C1=C2N([H])C([H])=C(C2=C(C([H])=N1)C(=O)N1C([H])([H])C([H])([H])C1([H])[H])C([H])([H])[H])C1=C([H])C([H])=C([H])C(Cl)=C1[H]
[H]N(C1=C2N([H])C([H])=C(C2=C(C([H])=N1)C(=O)N1C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])[H])C1=C([H])C([H])=C([H])C(Cl)=C1[H]
[H]N(C1=C2N([H])C([H])=C(C2=C(C([H])=N1)C(=O)N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])[H])C1=C([H])C([H])=C([H])C(Cl)=C1[H]
[H]N(C1=C2N([H])C([H])=C(C2=C(C([H])=N1)C(=O)N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])[H])C1=C([H])C([H])=C([H])C(Cl)=C1[H]
[H]N(C1=C2N([H])C([H])=C(C2=C(C([H])=N1)C(=O)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C([H])([H])[H])C1=C([H])C([H])=C([H])C(Cl)=C1[H]
[H]N(C1=C2N([H])C([H])=C(C2=C(C([H])=N1)C(=O)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C([H])([H])[H])C1=C([H])C([H])=C([H])C(Br)=C1[H]
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[H]N(C(=O)C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C([H])([H])[H])C1=C([H])C(=C(C([H])=C1[H])C([H])([H])[H])S(=O)(=O)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]N(C(=O)C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C([H])([H])[H])C1=C([H])C(=C(C([H])=C1C([H])([H])[H])C([H])([H])[H])S(=O)(=O)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]N(C(=O)C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C([H])([H])[H])C1=C([H])C(=C(C(=C1C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])S(=O)(=O)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]N(C(=O)C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C([H])([H])[H])C1=C([H])C(=C2C(=C1[H])C([H])([H])C([H])([H])C2([H])[H])S(=O)(=O)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]N(C(=O)C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C([H])([H])[H])C1=C([H])C(=C2C(=C1[H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])S(=O)(=O)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
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[H]N(C(=O)C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C([H])([H])[H])C1=C([H])C(=C(C(=C1[H])C([H])([H])[H])C([H])([H])[H])S(=O)(=O)N([H])C([H])([H])C1([H])C([H])([H])C1([H])[H]
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[H]N(C(=O)C1=C([H])C2=C(N([H])C1=O)C(OC([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])=C(OC([H])([H])[H])C([H])=C2[H])C([H])([H])C([H])([H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]N(C(=O)C1=C([H])C2=C(N([H])C1=O)C(OC([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])=C(OC([H])([H])[H])C([H])=C2[H])C([H])([H])C([H])([H])C1=C([H])C([H])=C(F)C([H])=C1[H]
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[H]N(C(=O)C1=C([H])C2=C([H])C([H])=C(OC([H])([H])[H])C(OC([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])=C2N=C1Cl)C([H])([H])C([H])([H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]N(C(=O)C1=C([H])C2=C([H])C([H])=C(OC([H])([H])[H])C(OC([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])=C2N=C1Cl)C([H])([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)C1=C([H])C2=C([H])C([H])=C(OC([H])([H])[H])C(OC([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])=C2N=C1Cl)C([H])([H])C([H])([H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]N(C(=O)C1=C([H])C2=C([H])C([H])=C(OC([H])([H])[H])C(OC([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])=C2N=C1Cl)C([H])([H])C([H])([H])C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]C1=C(C(=O)C2([H])C(C([H])([H])[H])(C([H])([H])[H])C2(C([H])([H])[H])C([H])([H])[H])C2=C(C([H])=C([H])C([H])=C2[H])N1C([H])([H])C([H])([H])C1=NSC(Cl)=N1
[H]C1=NC(=C(S1)C([H])([H])C([H])([H])N1C([H])=C(C(=O)C2([H])C(C([H])([H])[H])(C([H])([H])[H])C2(C([H])([H])[H])C([H])([H])[H])C2=C1C([H])=C([H])C([H])=C2[H])C([H])([H])[H]
[H]C1=C([H])C(=C([H])S1)C([H])([H])C([H])([H])N1C([H])=C(C(=O)C2([H])C(C([H])([H])[H])(C([H])([H])[H])C2(C([H])([H])[H])C([H])([H])[H])C2=C1C([H])=C([H])C([H])=C2[H]
[H]C1=C([H])C([H])=C(S1)C([H])([H])C([H])([H])N1C([H])=C(C(=O)C2([H])C(C([H])([H])[H])(C([H])([H])[H])C2(C([H])([H])[H])C([H])([H])[H])C2=C1C([H])=C([H])C([H])=C2[H]
[H]C1=C([H])N(C(=N1)C([H])([H])C([H])([H])N1C([H])=C(C(=O)C2([H])C(C([H])([H])[H])(C([H])([H])[H])C2(C([H])([H])[H])C([H])([H])[H])C2=C1C([H])=C([H])C([H])=C2[H])C([H])([H])[H]
[H]C1=C([H])N(C([H])=C1[H])C([H])([H])C([H])([H])N1C([H])=C(C(=O)C2([H])C(C([H])([H])[H])(C([H])([H])[H])C2(C([H])([H])[H])C([H])([H])[H])C2=C1C([H])=C([H])C([H])=C2[H]
[H]C1=C(C(=O)C2([H])C(C([H])([H])[H])(C([H])([H])[H])C2(C([H])([H])[H])C([H])([H])[H])C2=C(C([H])=C([H])C([H])=C2[H])N1C([H])([H])C([H])([H])C1=C([H])C([H])=NC([H])=C1[H]
[H]C1=C(C(=O)C2([H])C(C([H])([H])[H])(C([H])([H])[H])C2(C([H])([H])[H])C([H])([H])[H])C2=C(C([H])=C([H])C([H])=C2[H])N1C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])N=C1[H]
[H]C1=C(C(=O)C2([H])C(C([H])([H])[H])(C([H])([H])[H])C2(C([H])([H])[H])C([H])([H])[H])C2=C(C([H])=C([H])C([H])=C2[H])N1C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=N1
[H]C1=C(C(=O)C2([H])C(C([H])([H])[H])(C([H])([H])[H])C2(C([H])([H])[H])C([H])([H])[H])C2=C(C([H])=C([H])C([H])=C2[H])N1C([H])([H])C1=C([H])C([H])=NC([H])=C1[H]
[H]N([H])[C@]1([H])C2=C([H])C(=C(N=C2OC(C([H])([H])[H])(C([H])([H])[H])C1([H])[H])C1=C([H])C([H])=C(Cl)C([H])=C1Cl)C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]OC([H])([H])C(=O)N([H])[C@]1([H])C2=C([H])C(C3=C([H])C([H])=C(Cl)C([H])=C3[H])=C(N=C2OC(C([H])([H])[H])(C([H])([H])[H])C1([H])[H])C1=C([H])C([H])=C([H])C([H])=C1Cl
[H]OC([H])([H])C(=O)N([H])[C@]1([H])C2=C([H])C(C3=C([H])C([H])=C(Cl)C([H])=C3[H])=C(N=C2OC(C([H])([H])[H])(C([H])([H])[H])C1([H])[H])C1=C([H])C([H])=C(Cl)C([H])=C1Cl
[H]OC([H])([H])C(C(=O)N([H])[C@]1([H])C2=C([H])C(C3=C([H])C([H])=C(Cl)C([H])=C3[H])=C(N=C2OC(C([H])([H])[H])(C([H])([H])[H])C1([H])[H])C1=C([H])C([H])=C(Cl)C([H])=C1Cl)(C([H])([H])[H])C([H])([H])[H]
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[H]N(C([H])([H])C1=C([H])C(=C([H])C2=C1[C@]1([H])C([H])=C(C([H])([H])[H])C([H])([H])C([H])([H])[C@@]1([H])C(O2)(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])S(=O)(=O)C([H])([H])[H]
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[H]N(N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C(=O)C1=C(I)N(C(=N1)C1=C(Cl)C([H])=C(Cl)C([H])=C1[H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
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[H]N(C(=O)N1C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])[C@]([H])(C1=C([H])C([H])=C(F)C([H])=C1[H])C1=C([H])C([H])=C(Cl)C([H])=C1Cl)C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(C(=O)N1C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])[C@]([H])(C1=C([H])C([H])=C([H])C(Cl)=C1[H])C1=C([H])C([H])=C(Cl)C([H])=C1Cl)C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(C(=O)N1C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])[C@]([H])(C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H])C1=C([H])C([H])=C(Cl)C([H])=C1Cl)C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C(=O)N1C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])[C@]([H])(C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H])C1=C([H])C([H])=C(Cl)C([H])=C1Cl
[H]N(C(=O)N1C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])[C@]([H])(C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])C1=C([H])C([H])=C(Cl)C([H])=C1Cl)C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
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[H]N(C(=O)N1C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])C([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
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[H]N(C(=S)N1C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])C([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(C(=O)N1C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])[C@]([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C(Cl)C([H])=C1Cl)C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(C(=O)N1C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])[C@]([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C(Cl)C(Cl)=C1[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(C(=O)N1C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])[C@]([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C(Cl)=C([H])C([H])=C1Cl)C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(C(=O)N1C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])[C@]([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C(Cl)C([H])=C([H])C([H])=C1Cl)C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(C(=O)N1C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])[C@]([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C(Br)C([H])=C1F)C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(C(=O)N1C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])[C@]([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C(F)C([H])=C1Cl)C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(C(=O)N1C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])[C@]([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C(Cl)C([H])=C1F)C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])[C@@]([H])(N1C([H])([H])C([H])([H])N(C(=O)C2([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C(Cl)C([H])=C1Cl
[H]C1=C([H])C([H])=C(C([H])=C1[H])[C@@]([H])(N1C([H])([H])C([H])([H])N(C(=O)C2([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C(Cl)C([H])=C1Cl
[H]C1=C([H])C([H])=C(C([H])=C1[H])[C@@]([H])(N1C([H])([H])C([H])([H])N(C(=O)C2([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C(Cl)C([H])=C1Cl
[H]C1=C([H])C([H])=C(C([H])=C1[H])[C@@]([H])(N1C([H])([H])C([H])([H])N(C(=O)N2C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C(Cl)C([H])=C1Cl
[H]C1=C([H])C([H])=C(C([H])=C1[H])[C@@]([H])(N1C([H])([H])C([H])([H])N(C(=O)N2C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C(Cl)C([H])=C1Cl
[H]N(C(=O)N1C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])[C@]([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C(Cl)C([H])=C1Cl)C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]N(N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C(=O)N1C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])[C@]([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C(Cl)C([H])=C1Cl
[H]N(C(=S)N1C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])[C@]([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C(Cl)C([H])=C1Cl)C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N([H])C1=C(OC2=NC(C3=C([H])C([H])=C(Cl)C([H])=C3Cl)=C(C([H])=C12)C1=C([H])C([H])=C(Cl)C([H])=C1[H])C(=O)C([H])([H])[H]
[H]N([H])C1=C(OC2=NC(C3=C([H])C([H])=C(Cl)C([H])=C3Cl)=C(C([H])=C12)C1=C([H])C([H])=C(Cl)C([H])=C1[H])C(=O)C([H])([H])C([H])([H])[H]
[H]N([H])C1=C(OC2=NC(C3=C([H])C([H])=C([H])C([H])=C3Cl)=C(C([H])=C12)C1=C([H])C([H])=C(Cl)C([H])=C1[H])C(=O)C([H])([H])C([H])([H])[H]
[H]N([H])C1=C(OC2=NC(C3=C([H])C([H])=C(Cl)C([H])=C3Cl)=C(C([H])=C12)C1=C([H])C([H])=C(Cl)C([H])=C1[H])C(=O)C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N([H])C1=C(OC2=NC(C3=C([H])C([H])=C([H])C([H])=C3Cl)=C(C([H])=C12)C1=C([H])C([H])=C(Cl)C([H])=C1[H])C(=O)C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N([H])C1=C(OC2=NC(C3=C([H])C([H])=C(Cl)C([H])=C3Cl)=C(C([H])=C12)C1=C([H])C([H])=C(Cl)C([H])=C1[H])C(=O)C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N([H])C1=C(OC2=NC(C3=C([H])C([H])=C(Cl)C([H])=C3Cl)=C(C([H])=C12)C1=C([H])C([H])=C(Cl)C([H])=C1[H])C(=O)C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]N([H])C1=C(OC2=NC(C3=C([H])C([H])=C([H])C([H])=C3Cl)=C(C([H])=C12)C1=C([H])C([H])=C(Cl)C([H])=C1[H])C(=O)C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]OC(C(=O)C1=C(N([H])[H])C2=C([H])C(C3=C([H])C([H])=C(Cl)C([H])=C3[H])=C(N=C2O1)C1=C([H])C([H])=C([H])C([H])=C1Cl)(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)C([H])([H])[H])C1=C(OC2=NC(C3=C([H])C([H])=C([H])C([H])=C3Cl)=C(C([H])=C12)C1=C([H])C([H])=C(Cl)C([H])=C1[H])C(=O)C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)N(C([H])([H])[H])C([H])([H])[H])C1=C(OC2=NC(C3=C([H])C([H])=C([H])C([H])=C3Cl)=C(C([H])=C12)C1=C([H])C([H])=C(Cl)C([H])=C1[H])C(=O)C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)C([H])([H])N([H])C([H])([H])[H])C1=C(OC2=NC(C3=C([H])C([H])=C([H])C([H])=C3Cl)=C(C([H])=C12)C1=C([H])C([H])=C(Cl)C([H])=C1[H])C(=O)C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]OC([H])([H])C(=O)N([H])C1=C(OC2=NC(C3=C([H])C([H])=C([H])C([H])=C3Cl)=C(C([H])=C12)C1=C([H])C([H])=C(Cl)C([H])=C1[H])C(=O)C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]OC([H])([H])C(=O)N([H])C1=C(OC2=NC(C3=C([H])C([H])=C([H])C([H])=C3Cl)=C(C([H])=C12)C1=C([H])C([H])=C(Cl)C([H])=C1[H])C(=O)C([H])(C([H])([H])[H])C([H])([H])[H]
[H]OC(C(=O)C1=C(N([H])C(=O)C([H])([H])[H])C2=C([H])C(C3=C([H])C([H])=C(Cl)C([H])=C3[H])=C(N=C2O1)C1=C([H])C([H])=C([H])C([H])=C1Cl)(C([H])([H])[H])C([H])([H])[H]
[H]C([H])([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C1=NC2=C(N1C([H])([H])C1([H])C([H])([H])C1([H])[H])C([H])([H])C([H])([H])N(C2([H])[H])S(=O)(=O)C([H])([H])[H]
[H]C([H])([H])C(C1=NC2=C(N1C([H])([H])C1([H])C([H])([H])C1([H])[H])C([H])([H])C([H])([H])N(C2([H])[H])S(=O)(=O)C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]C([H])([H])OC([H])([H])C([H])([H])S(=O)(=O)N1C([H])([H])C2=C(N(C(=N2)C([H])([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C2([H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]C([H])([H])OC([H])([H])C([H])([H])S(=O)(=O)N1C([H])([H])C2=C(N(C(=N2)C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C2([H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])S(=O)(=O)N1C([H])([H])C2=C(N(C(=N2)C([H])([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C2([H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]C([H])([H])C1=C(C(=NO1)C([H])([H])[H])S(=O)(=O)N1C([H])([H])C2=C(N(C(=N2)C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C2([H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]C([H])([H])C([H])([H])C([H])([H])C([H])([H])C(=O)N1C([H])([H])C2=C(N(C(=N2)C([H])([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C2([H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N(C(=O)N1C([H])([H])C2=C(N(C(=N2)C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C2([H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H])C([H])([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N(C(=O)N1C([H])([H])C2=C(N(C(=N2)C([H])([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C2([H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H])C([H])([H])[H]
[H]N(C(=O)C1=NN(C(N2C(=C([H])C([H])=C2C([H])([H])[H])C([H])([H])[H])=C1C([H])([H])[H])C1=C([H])C([H])=C(Cl)C([H])=C1Cl)C([H])([H])C([H])([H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]N(C(=O)C1=NN(C(N2C(=C([H])C([H])=C2C([H])([H])[H])C([H])([H])[H])=C1C([H])([H])[H])C1=C([H])C([H])=C(Cl)C([H])=C1Cl)C([H])([H])C1=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C(OC([H])([H])[H])=C1Br
[H]N(C(=O)C1=NN(C(N2C(=C([H])C([H])=C2C([H])([H])[H])C([H])([H])[H])=C1C([H])([H])[H])C1=C([H])C([H])=C(Cl)C([H])=C1Cl)C([H])([H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]N(C(=O)C1=NN(C(N2C(=C([H])C([H])=C2C([H])([H])[H])C([H])([H])[H])=C1C([H])([H])[H])C1=C([H])C([H])=C(Cl)C([H])=C1Cl)C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]N(C(=O)C1=NN(C(N2C([H])=C([H])C([H])=C2[H])=C1C([H])([H])[H])C1=C([H])C([H])=C(Cl)C([H])=C1Cl)C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(C(=O)C1=NN(C(N2C([H])=C([H])C([H])=C2[H])=C1C([H])([H])[H])C1=C([H])C([H])=C(Cl)C([H])=C1Cl)C1([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(C(=O)C1=NN(C(N2C([H])=C([H])C([H])=C2[H])=C1C([H])([H])[H])C1=C([H])C([H])=C(Cl)C([H])=C1Cl)C([H])([H])C([H])([H])C1=C([H])C([H])=C(Cl)C([H])=C1Cl
[H]N(C(=O)C1=NN(C(N2C([H])=C([H])C([H])=C2[H])=C1C([H])([H])[H])C1=C([H])C([H])=C(Cl)C([H])=C1Cl)C([H])([H])C([H])([H])C1=C([H])C([H])=C(OC([H])([H])[H])C(Cl)=C1[H]
[H]N(C(=O)C1=NN(C(N2C([H])=C([H])C([H])=C2[H])=C1C([H])([H])[H])C1=C([H])C([H])=C(Cl)C([H])=C1Cl)C([H])([H])C([H])([H])C1=C([H])C([H])=C(Cl)C(Cl)=C1[H]
[H]N(C(=O)C1=NN(C(N2C([H])=C([H])C([H])=C2[H])=C1C([H])([H])[H])C1=C([H])C([H])=C(Cl)C([H])=C1Cl)C([H])([H])C([H])([H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]N(C(=O)C1=NN(C(N2C([H])=C([H])C([H])=C2[H])=C1C([H])([H])[H])C1=C([H])C([H])=C(Cl)C([H])=C1Cl)C([H])([H])C1=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C(OC([H])([H])[H])=C1Br
[H]N(C(=O)C1=NN(C(N2C([H])=C([H])C([H])=C2[H])=C1C([H])([H])[H])C1=C([H])C([H])=C(Cl)C([H])=C1Cl)C([H])([H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]N(C(=O)C1=NN(C(N2C([H])=C([H])C([H])=C2[H])=C1C([H])([H])[H])C1=C([H])C([H])=C(Cl)C([H])=C1Cl)C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]N(C(=O)C1=NN(C(N2C([H])=C([H])C([H])=C2[H])=C1C([H])([H])[H])C1=C([H])C([H])=C(Cl)C(Cl)=C1[H])[C@]12C([H])([H])[C@@]3([H])C([H])([H])[C@]([H])(C([H])([H])[C@]([H])(C3([H])[H])C1([H])[H])C2([H])[H]
[H]N(C(=O)N(C([H])([H])C(=O)N1C2=C(C([H])=C([H])C([H])=C2[H])N2C([H])=C([H])C([H])=C2[C@]1([H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])C([H])(C([H])([H])[H])C([H])([H])[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)C([H])([H])OC1=C(C([H])=C(C([H])=C1C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C1=C(C(=O)N([H])[C@@]2([H])C([H])([H])C([H])([H])S(=O)(=O)C2([H])[H])C2=C(S1)C([H])([H])C([H])([H])C([H])([H])C2([H])[H]
[H]C1=NC(OC([H])([H])[H])=C(C([H])=C1Br)C([H])([H])N1C([H])([H])C2=C(N(C(=N2)C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C2([H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]C1=C(C([H])=C(C2=C1OC(C([H])([H])[H])(C([H])([H])[H])[C@]1([H])C([H])([H])C([H])([H])C(=C([H])[C@@]21[H])C([H])([H])[H])[S@](=O)C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]C1=C(C([H])=C(C#N)C2=C1OC(C([H])([H])[H])(C([H])([H])[H])[C@]1([H])C([H])([H])C([H])([H])C(=C([H])[C@@]21[H])C([H])([H])[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]N([H])C1=C([H])C(=C([H])C2=C1[C@]1([H])C([H])=C(C([H])([H])[H])C([H])([H])C([H])([H])[C@@]1([H])C(O2)(C([H])([H])[H])C([H])([H])[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]N(C(=O)C([H])([H])[H])C1=C([H])C(=C([H])C2=C1[C@]1([H])C([H])=C(C([H])([H])[H])C([H])([H])C([H])([H])[C@@]1([H])C(O2)(C([H])([H])[H])C([H])([H])[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]N(C(=O)N([H])C([H])([H])[H])C1=C([H])C(=C([H])C2=C1[C@]1([H])C([H])=C(C([H])([H])[H])C([H])([H])C([H])([H])[C@@]1([H])C(O2)(C([H])([H])[H])C([H])([H])[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]N(C(=O)C1=C([H])C([H])=NC([H])=C1[H])C1=C([H])C(=C([H])C2=C1[C@]1([H])C([H])=C(C([H])([H])[H])C([H])([H])C([H])([H])[C@@]1([H])C(O2)(C([H])([H])[H])C([H])([H])[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]N(C1=C([H])C(=C([H])C2=C1[C@]1([H])C([H])=C(C([H])([H])[H])C([H])([H])C([H])([H])[C@@]1([H])C(O2)(C([H])([H])[H])C([H])([H])[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])S(=O)(=O)C([H])([H])[H]
[H]C1=NN(C([H])=N1)C([H])([H])C1=C(N(N=C1C(=O)N1C([H])([H])C([H])([H])N(C2=C([H])C([H])=C([H])C(Cl)=C2Cl)C([H])([H])C1([H])[H])C1=C([H])C([H])=C([H])C([H])=C1Cl)C1=C([H])C([H])=C(Br)C([H])=C1[H]
[H]C1=NN(C([H])=N1)C([H])([H])C1=C(N(N=C1C(=O)N1C([H])([H])C([H])([H])N(C2=C([H])C([H])=C([H])C(=C2C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C([H])C([H])=C1Cl)C1=C([H])C([H])=C(Br)C([H])=C1[H]
[H]N(C(=O)C1=NN(C(=C1C([H])([H])N1N=C([H])N=C1[H])C1=C([H])C([H])=C(Cl)C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1Cl)C([H])([H])C1=C(C([H])=C(Br)C([H])=C1[H])C([H])([H])[H]
[H]N(C(=O)C1=NN(C(=C1C([H])([H])N1N=C([H])N=C1[H])C1=C([H])C([H])=C(Cl)C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1Cl)C([H])([H])C1=C(C([H])=C(Cl)C([H])=C1Cl)C([H])([H])[H]
[H]N(C(=O)C1=NN(C(=C1C([H])([H])N1N=C([H])N=C1[H])C1=C([H])C([H])=C(Br)C([H])=C1[H])C1=C([H])C([H])=C(Cl)C([H])=C1Cl)C([H])([H])C1=C(C([H])=C(Br)C([H])=C1[H])C([H])([H])[H]
[H]N(C(=O)C1=NN(C(=C1C([H])([H])N1N=C([H])N=C1[H])C1=C([H])C([H])=C(Br)C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1Cl)C([H])([H])C1=C(C([H])=C(Br)C([H])=C1[H])C([H])([H])[H]
[H]N(C(=O)C1=NN(C(=C1C([H])([H])N1N=C([H])N=C1[H])C1=C([H])C([H])=C(Br)C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1Cl)C([H])([H])C1=C(C([H])=C(Cl)C([H])=C1Cl)C([H])([H])[H]
[H]N(C(=O)C1=NN(C(=C1C([H])([H])N1N=C([H])N=C1[H])C1=C([H])C([H])=C(Br)C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1Cl)[C@]1([H])C([H])([H])[C@@]1([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)C1=NN(C(=C1C([H])([H])N1N=C([H])N=C1[H])C1=C([H])C([H])=C(Br)C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1Cl)C1(C2=C([H])C([H])=C(Cl)C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N(C(=O)C1=NN(C(=C1C([H])([H])N1N=C([H])N=C1[H])C1=C([H])C([H])=C(Br)C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1Cl)C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]C1=NN(C([H])=N1)C([H])([H])C1=C(N(N=C1C(=O)N1C([H])([H])C([H])([H])N(C2=C([H])C([H])=C([H])C(Cl)=C2[H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C([H])C([H])=C1Cl)C1=C([H])C([H])=C(Br)C([H])=C1[H]
[H]N(C(=O)C1=C(Cl)N(C(Cl)=N1)C1=C([H])C([H])=C([H])C([H])=C1[H])[C@]12C([H])([H])[C@@]3([H])C([H])([H])[C@]([H])(C([H])([H])[C@]([H])(C3([H])[H])C1([H])[H])C2([H])[H]
[H]N(C(=O)C1=C(N(C(=N1)C([H])([H])[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])[H])[C@]12C([H])([H])[C@@]3([H])C([H])([H])[C@]([H])(C([H])([H])[C@]([H])(C3([H])[H])C1([H])[H])C2([H])[H]
[H]N(C(=O)C1=C(Cl)N(C(=N1)C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H])[C@]12C([H])([H])[C@@]3([H])C([H])([H])[C@]([H])(C([H])([H])[C@]([H])(C3([H])[H])C1([H])[H])C2([H])[H]
[H]N(C(=O)C1=C(Br)N(C(=N1)C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H])[C@]12C([H])([H])[C@@]3([H])C([H])([H])[C@]([H])(C([H])([H])[C@]([H])(C3([H])[H])C1([H])[H])C2([H])[H]
[H]N(C(=O)C1=C(SC([H])([H])[H])N(C(=N1)C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H])[C@]12C([H])([H])[C@@]3([H])C([H])([H])[C@]([H])(C([H])([H])[C@]([H])(C3([H])[H])C1([H])[H])C2([H])[H]
[H]C1=C([H])C(=C([H])C([H])=C1Cl)[C@]1([H])N(C2=C(Cl)C([H])=C(Cl)C([H])=C2[H])C([H])([H])[C@@]([H])(C([H])([H])C2=C([H])C([H])=C(F)C(F)=C2[H])C([H])([H])C1([H])[H]
[H]C1=C([H])C(=C([H])C([H])=C1Cl)N1C([H])([H])[C@@]([H])(C([H])([H])C2=C([H])C([H])=C(F)C(F)=C2[H])C([H])([H])C([H])([H])[C@]1([H])C1=C([H])C([H])=C(Cl)C([H])=C1Cl
[H]C1=C([H])C(=C([H])C([H])=C1Cl)N1C(=O)[C@@]([H])(C([H])([H])C2=C([H])C([H])=C(F)C(F)=C2[H])C([H])([H])C([H])([H])[C@]1([H])C1=C([H])C([H])=C(Cl)C([H])=C1Cl
[H]C1=C([H])C(=C([H])C([H])=C1Cl)N1C([H])([H])[C@]([H])(C([H])([H])C2=C([H])C([H])=C(F)C(F)=C2[H])C([H])([H])C([H])([H])[C@]1([H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]C1=C([H])C(=C([H])C([H])=C1Cl)N1C(=O)[C@]([H])(C([H])([H])C2=C([H])C([H])=C(F)C(F)=C2[H])C([H])([H])C([H])([H])[C@]1([H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]OC(=O)C1=C([H])C(=C([H])C2=C1[C@]1([H])C([H])=C(C([H])([H])[H])C([H])([H])C([H])([H])[C@@]1([H])C(O2)(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]N([H])C(=O)C1=C([H])C(=C([H])C2=C1[C@]1([H])C([H])=C(C([H])([H])[H])C([H])([H])C([H])([H])[C@@]1([H])C(O2)(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]N(C(=O)C1=C([H])C(=C([H])C2=C1[C@]1([H])C([H])=C(C([H])([H])[H])C([H])([H])C([H])([H])[C@@]1([H])C(O2)(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])[H]
[H]C1=C(C([H])=C(C(=O)N(C([H])([H])[H])C([H])([H])[H])C2=C1OC(C([H])([H])[H])(C([H])([H])[H])[C@]1([H])C([H])([H])C([H])([H])C(=C([H])[C@@]21[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]N([H])C(=O)C([H])([H])N([H])C(=O)C1=C([H])C(=C([H])C2=C1[C@]1([H])C([H])=C(C([H])([H])[H])C([H])([H])C([H])([H])[C@@]1([H])C(O2)(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]OC([H])([H])C([H])(N([H])C(=O)C1=C([H])C(=C([H])C2=C1[C@]1([H])C([H])=C(C([H])([H])[H])C([H])([H])C([H])([H])[C@@]1([H])C(O2)(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])O[H]
[H]N([H])C1=C([H])C(=C([H])C2=C1[C@]1([H])C([H])=C(C([H])([H])[H])C([H])([H])C([H])([H])[C@@]1([H])C(O2)(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]C1=C(C([H])=C(C#N)C2=C1OC(C([H])([H])[H])(C([H])([H])[H])[C@]1([H])C([H])([H])C([H])([H])C(=C([H])[C@@]21[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]N(C(=O)OC([H])([H])[H])C1=C([H])C(=C([H])C2=C1[C@]1([H])C([H])=C(C([H])([H])[H])C([H])([H])C([H])([H])[C@@]1([H])C(O2)(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]N(C1=C([H])C(=C([H])C2=C1[C@]1([H])C([H])=C(C([H])([H])[H])C([H])([H])C([H])([H])[C@@]1([H])C(O2)(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])S(=O)(=O)C([H])([H])[H]
[H]N([H])C(=O)N([H])C1=C([H])C(=C([H])C2=C1[C@]1([H])C([H])=C(C([H])([H])[H])C([H])([H])C([H])([H])[C@@]1([H])C(O2)(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]N(C(=O)N([H])C([H])([H])[H])C1=C([H])C(=C([H])C2=C1[C@]1([H])C([H])=C(C([H])([H])[H])C([H])([H])C([H])([H])[C@@]1([H])C(O2)(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]N(C(=O)C([H])([H])[H])C1=C([H])C(=C([H])C2=C1[C@]1([H])C([H])=C(C([H])([H])[H])C([H])([H])C([H])([H])[C@@]1([H])C(O2)(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]C1=C([H])C(=C([H])C([H])=C1Cl)N1C([H])([H])[C@]([H])(C([H])([H])N2C([H])([H])C([H])([H])N(C(=O)OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C2([H])[H])C([H])([H])C([H])([H])[C@@]1([H])C1=C([H])C([H])=C(Cl)C([H])=C1Cl
[H]N(C([H])([H])C([H])([H])[C@]1([H])C([H])([H])N(C2=C([H])C([H])=C(Cl)C([H])=C2[H])[C@@]([H])(C2=C([H])C([H])=C(Cl)C([H])=C2Cl)C([H])([H])C1([H])[H])S(=O)(=O)C1([H])C([H])([H])C1([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C(C#N)C([H])=C1[H])C([H])([H])C([H])([H])[C@@]1([H])C([H])([H])N(C2=C([H])C([H])=C(Cl)C([H])=C2[H])[C@]([H])(C2=C([H])C([H])=C(Cl)C([H])=C2Cl)C([H])([H])C1([H])[H]
[H]N(C(=O)C([H])([H])[H])C([H])([H])C([H])([H])[C@@]1([H])C([H])([H])N(C2=C([H])C([H])=C(Cl)C([H])=C2[H])[C@]([H])(C2=C([H])C([H])=C(Cl)C([H])=C2Cl)C([H])([H])C1([H])[H]
[H]N(C([H])([H])C([H])([H])[C@@]1([H])C([H])([H])N(C2=C([H])C([H])=C(Cl)C([H])=C2[H])[C@]([H])(C2=C([H])C([H])=C(Cl)C([H])=C2Cl)C([H])([H])C1([H])[H])S(=O)(=O)C1=C([H])N=C([H])C([H])=C1[H]
[H]N(C([H])([H])C([H])([H])[C@@]1([H])C([H])([H])N(C2=C([H])C([H])=C(Cl)C([H])=C2[H])[C@]([H])(C2=C([H])C([H])=C(Cl)C([H])=C2Cl)C([H])([H])C1([H])[H])S(=O)(=O)C1=C([H])C([H])=C(C#N)C([H])=C1[H]
[H]N([H])C([H])([H])C([H])([H])[C@@]1([H])C([H])([H])N(C2=C([H])C([H])=C(Cl)C([H])=C2[H])[C@]([H])(C2=C([H])C([H])=C(Cl)C([H])=C2Cl)C([H])([H])C1([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C(C#N)C([H])=C1[H])C([H])([H])[C@@]1([H])C([H])([H])N(C2=C([H])C([H])=C(Cl)C([H])=C2[H])[C@]([H])(C2=C([H])C([H])=C(Cl)C([H])=C2Cl)C([H])([H])C1([H])[H]
[H]N(C([H])([H])[C@@]1([H])C([H])([H])N(C2=C([H])C([H])=C(Cl)C([H])=C2[H])[C@]([H])(C2=C([H])C([H])=C(Cl)C([H])=C2Cl)C([H])([H])C1([H])[H])S(=O)(=O)C1=C([H])N=C([H])C([H])=C1[H]
[H]N(C([H])([H])[C@@]1([H])C([H])([H])N(C2=C([H])C([H])=C(Cl)C([H])=C2[H])[C@]([H])(C2=C([H])C([H])=C(Cl)C([H])=C2Cl)C([H])([H])C1([H])[H])S(=O)(=O)C1([H])C([H])([H])C1([H])[H]
[H]N([H])C([H])([H])[C@@]1([H])C([H])([H])N(C2=C([H])C([H])=C(Cl)C([H])=C2[H])[C@]([H])(C2=C([H])C([H])=C(Cl)C([H])=C2Cl)C([H])([H])C1([H])[H]
[H]OC([H])([H])[C@]([H])(N([H])C(=O)C([H])([H])C([H])([H])C([H])([H])C(\[H])=C(\[H])C([H])([H])C(\[H])=C(\[H])C([H])([H])C(\[H])=C(\[H])C([H])([H])C(\[H])=C(\[H])C([H])([H])C([H])([H])OC(=O)C1=C([H])C([H])=C([H])C2=C1O[C@@](O2)(C([H])([H])[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)C1=C(N(C([H])=N1)C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H])C([H])([H])[C@@]1([H])C([H])([H])[C@]2([H])C([H])([H])[C@]([H])(C1([H])[H])C2(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)C1=C(N(C(=N1)C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H])C([H])([H])[C@@]1([H])C([H])([H])[C@]2([H])C([H])([H])[C@]([H])(C1([H])[H])C2(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)C1=C(N(C(=N1)C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H])[C@]12C([H])([H])[C@@]3([H])C([H])([H])[C@]([H])(C([H])([H])[C@]([H])(C3([H])[H])C1([H])[H])C2([H])[H]
[H]N(C(=O)C1=C(N(C(=N1)C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1C(F)(F)F
[H]N(C(=O)C1=C(N(C(=N1)C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])[H])[C@]12C([H])([H])[C@@]3([H])C([H])([H])[C@]([H])(C([H])([H])[C@]([H])(C3([H])[H])C1([H])[H])C2([H])[H]
[H]N(C(=O)C1=C(N(C(=N1)C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])[C@]12C([H])([H])[C@@]3([H])C([H])([H])[C@]([H])(C([H])([H])[C@]([H])(C3([H])[H])C1([H])[H])C2([H])[H]
[H]N(C(=O)C1=C(N(C(=N1)C([H])([H])C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H])[C@]12C([H])([H])[C@@]3([H])C([H])([H])[C@]([H])(C([H])([H])[C@]([H])(C3([H])[H])C1([H])[H])C2([H])[H]
[H]N(C(=O)C1=C([H])N(C(=N1)C([H])([H])C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H])[C@]12C([H])([H])[C@@]3([H])C([H])([H])[C@]([H])(C([H])([H])[C@]([H])(C3([H])[H])C1([H])[H])C2([H])[H]
[H]N(C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])S(=O)(=O)[C@@]1([H])C([H])([H])N(C2=C([H])C([H])=C(Cl)C([H])=C2[H])[C@]([H])(C2=C([H])C([H])=C(Cl)C([H])=C2Cl)C([H])([H])C1([H])[H]
[H]N(C(=O)[C@@]1([H])C([H])([H])N(C2=C([H])C([H])=C(Cl)C([H])=C2[H])[C@]([H])(C2=C([H])C([H])=C(Cl)C([H])=C2Cl)C([H])([H])C1([H])[H])C1([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(C(=O)[C@@]1([H])C([H])([H])N(C2=C([H])C([H])=C(Cl)C([H])=C2[H])[C@]([H])(C2=C([H])C([H])=C(Cl)C([H])=C2Cl)C([H])([H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]N(C(=O)[C@@]1([H])C([H])([H])N(C2=C([H])C([H])=C(Cl)C([H])=C2[H])[C@]([H])(C2=C([H])C([H])=C(Cl)C([H])=C2Cl)C([H])([H])C1([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])C(=C([H])C([H])=C1Cl)N1C([H])([H])[C@]([H])(C([H])([H])N2C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C2([H])[H])C([H])([H])C([H])([H])[C@@]1([H])C1=C([H])C([H])=C(Cl)C([H])=C1Cl
[H]C1=C([H])C(=C([H])C([H])=C1Cl)N1C([H])([H])[C@]([H])(C([H])([H])N2C([H])([H])C([H])([H])N(C(=O)C([H])([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C2([H])[H])C([H])([H])C([H])([H])[C@@]1([H])C1=C([H])C([H])=C(Cl)C([H])=C1Cl
[H]N(C([H])([H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])S(=O)(=O)[C@@]1([H])C([H])([H])N(C2=C([H])C([H])=C(Cl)C([H])=C2[H])[C@]([H])(C2=C([H])C([H])=C(Cl)C([H])=C2Cl)C([H])([H])C1([H])[H]
[H]C1=C([H])C(=C([H])C([H])=C1Cl)N1C([H])([H])[C@@]([H])(C([H])([H])C([H])([H])[C@@]1([H])C1=C([H])C([H])=C(Cl)C([H])=C1Cl)S(=O)(=O)N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]C1=C([H])C(=C([H])C([H])=C1Cl)N1C([H])([H])[C@]([H])(C([H])([H])N2C([H])([H])C([H])([H])N(C(=O)C([H])([H])[H])C([H])([H])C2([H])[H])C([H])([H])C([H])([H])[C@@]1([H])C1=C([H])C([H])=C(Cl)C([H])=C1Cl
[H]C1=C([H])C(=C([H])C([H])=C1Cl)N1C([H])([H])[C@]([H])(C([H])([H])N2C([H])([H])C([H])([H])N(C([H])([H])C2([H])[H])S(=O)(=O)C2([H])C([H])([H])C2([H])[H])C([H])([H])C([H])([H])[C@@]1([H])C1=C([H])C([H])=C(Cl)C([H])=C1Cl
[H]C1=C([H])C(=C([H])C([H])=C1Cl)N1C([H])([H])[C@]([H])(C([H])([H])N2C([H])([H])C([H])([H])N(C([H])([H])C2([H])[H])S(=O)(=O)C([H])([H])[H])C([H])([H])C([H])([H])[C@@]1([H])C1=C([H])C([H])=C(Cl)C([H])=C1Cl
[H]N1C([H])([H])C([H])([H])N(C([H])([H])[C@@]2([H])C([H])([H])N(C3=C([H])C([H])=C(Cl)C([H])=C3[H])[C@]([H])(C3=C([H])C([H])=C(Cl)C([H])=C3Cl)C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]C([H])([H])C(C(=O)N1C([H])([H])C2=C(N(C(=N2)C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C2([H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])S(=O)(=O)N1C([H])([H])C2=C(N(C(=N2)C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C2([H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]C1=C([H])C([H])=C(C([H])=N1)S(=O)(=O)N1C([H])([H])C2=C(N(C(=N2)C([H])([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C2([H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]C1=C([H])C([H])=C(C([H])=N1)S(=O)(=O)N1C([H])([H])C2=C(N(C(=N2)C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C2([H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)N1C([H])([H])C2=C(N(C(=N2)C([H])([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C2([H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)N1C([H])([H])C2=C(N(C(=N2)C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C2([H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]C1=C(C(=NO1)C([H])([H])[H])S(=O)(=O)N1C([H])([H])C2=C(N(C(=N2)C([H])([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C2([H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]C1=C(C(=NO1)C([H])([H])[H])S(=O)(=O)N1C([H])([H])C2=C(N(C(=N2)C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C2([H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]C([H])([H])C1=C(C(=NO1)C([H])([H])[H])S(=O)(=O)N1C([H])([H])C2=C(N(C(=N2)C([H])([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C2([H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]C([H])([H])N(C(=O)N1C([H])([H])C2=C(N(C(=N2)C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C2([H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C2=C(N(C(=N2)C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C2([H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C2=C(N(C(=N2)C([H])([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C2([H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]C([H])([H])C([H])([H])C([H])([H])OC(=O)N1C([H])([H])C2=C(N(C(=N2)C([H])([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C2([H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]OC1=C([H])C(=C([H])C2=C1C1=C(C([H])([H])C([H])([H])N(C#C[H])C1([H])[H])C(O2)(C([H])([H])[H])C([H])([H])[H])[C@@]([H])(C([H])([H])[H])[C@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]N(C(=O)C1=C([H])C2=C(S1)N(N=C2C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(F)C([H])=C1[H])C([H])([H])C1=C(C([H])=C(N([H])C1=O)C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])P(=O)(C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C2=C(C([H])=C1[H])N(C([H])([H])[H])[C@@]([H])(C([H])([H])[H])C2(C([H])([H])[H])C([H])([H])[H]
[H]N([H])C(=O)C1=C([H])C([H])=C([H])C([H])=C1OC([H])([H])C(=O)C1=C(N(C(=C1[H])C([H])([H])[H])C([H])([H])C([H])([H])C1=C([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])[H]
[H]OC1=C(OC([H])([H])[H])C([H])=C([H])C(=C1[H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])N2C3=C(C([H])=C(C([H])=C3[H])C([H])([H])[H])C3=C2[C@@]1([H])C([H])([H])C([H])([H])C3([H])[H]
[H]N(C(=O)C([H])([H])OC1=C([H])C([H])=C(C([H])=C1C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])[C@]([H])(C([H])([H])[H])C1([H])[H])C1=C([H])C([H])=C2OC([H])([H])OC2=C1[H])C([H])([H])C1=C(F)C([H])=C([H])C([H])=C1[H]
[H]N(C1=C2C(SC3=C2C([H])([H])C([H])([H])C([H])([H])C3([H])[H])=NC(=N1)C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])[C@]1([H])C2=C(C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C1([H])[H]
[H]N1C(=O)N(C2=C([H])C([H])=C([H])C([H])=C12)C1([H])C([H])([H])C([H])([H])N(C(=O)C([H])([H])C([H])([H])C(=O)C2=C([H])C3=C(C([H])=C2[H])C([H])([H])C([H])([H])C([H])([H])C3([H])[H])C([H])([H])C1([H])[H]
[H]C1=C([H])C(=C([H])C(=C1[H])C1=NN=C(SC([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H])N1C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])S(=O)(=O)C([H])(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H]
[H]N(C(=O)[C@@]1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C([H])([H])[H])C1=C([H])C(=C(C(=C1[H])C(F)(F)F)C([H])([H])[H])C([H])([H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]N(C(=O)[C@@]1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C([H])([H])[H])C1=C([H])C(=C(C([H])=C1F)C([H])([H])[H])C([H])([H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]N(C(=O)C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C([H])([H])[H])C1=C([H])C(=C(C([H])=C1F)C([H])([H])[H])C([H])([H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]N(C(=O)[C@@]1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C([H])([H])[H])C1=C([H])C(=C(C([H])=C1C([H])([H])[H])C([H])([H])[H])C([H])([H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]N(C(=O)C(C([H])([H])[H])(C(F)(F)F)C(F)(F)F)C1=C([H])C2=C(C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])[C@@]2([H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]N(C(=O)C(C([H])([H])[H])(C(F)(F)F)C(F)(F)F)C1=C([H])C(=C(C([H])=C1[H])C([H])([H])[H])C([H])([H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]N(C(=O)[C@@]1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C([H])([H])[H])C1=C([H])C(=C(C([H])=C1[H])C([H])([H])[H])C([H])([H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]N(C(=O)C(C([H])([H])[H])(C(F)(F)F)C(F)(F)F)C1=C([H])C(=C(C(=C1[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]N(C(=O)[C@@]1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C([H])([H])[H])C1=C([H])C(=C(C(=C1[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]N(C(=O)C1=C([H])C(=C(C([H])=C1[H])C([H])([H])[H])C([H])([H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])[C@]1([H])C(C([H])([H])[H])(C([H])([H])[H])[C@]2([H])C([H])([H])C([H])([H])[C@@]1(C([H])([H])[H])C2([H])[H]
[H]N(C(=O)C1=C([H])C(=C(C([H])=C1[H])C([H])([H])[H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])[C@]1([H])C(C([H])([H])[H])(C([H])([H])[H])[C@]2([H])C([H])([H])C([H])([H])[C@@]1(C([H])([H])[H])C2([H])[H]
[H]N(C(=O)C1=C([H])C(=C(C([H])=C1[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])[C@]1([H])C(C([H])([H])[H])(C([H])([H])[H])[C@]2([H])C([H])([H])C([H])([H])[C@@]1(C([H])([H])[H])C2([H])[H]
[H]N(C(=O)C1=C([H])C(N2C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])=C(C([H])=C1[H])C([H])([H])[H])[C@]1([H])C(C([H])([H])[H])(C([H])([H])[H])[C@]2([H])C([H])([H])C([H])([H])[C@@]1(C([H])([H])[H])C2([H])[H]
[H]N(C(=O)C1=C([H])C(=C(C([H])=C1[H])C([H])([H])[H])C([H])([H])C([H])([H])C(=O)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])[C@]1([H])C(C([H])([H])[H])(C([H])([H])[H])[C@]2([H])C([H])([H])C([H])([H])[C@@]1(C([H])([H])[H])C2([H])[H]
[H]N(C(=O)C1=C([H])C(=C(C([H])=C1[H])C([H])([H])[H])C([H])([H])C(=O)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])[C@]1([H])C(C([H])([H])[H])(C([H])([H])[H])[C@]2([H])C([H])([H])C([H])([H])[C@@]1(C([H])([H])[H])C2([H])[H]
[H]N(C(=O)C1=C([H])C(C(=O)N2C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])=C(C([H])=C1[H])C([H])([H])[H])[C@]1([H])C(C([H])([H])[H])(C([H])([H])[H])[C@]2([H])C([H])([H])C([H])([H])[C@@]1(C([H])([H])[H])C2([H])[H]
[H]N(C(=O)N1N=C(C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])[C@@]([H])(C2=C([H])C([H])=C([H])C([H])=C2[H])C1([H])[H])C(C1=C([H])C([H])=C([H])C([H])=C1[H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)N1N=C(C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])[C@@]([H])(C2=C([H])C(F)=C([H])C([H])=C2[H])C1([H])[H])C(C1=C([H])C([H])=C(F)C([H])=C1[H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)N1N=C(C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])[C@@]([H])(C2=C(F)C([H])=C([H])C([H])=C2[H])C1([H])[H])C(C1=C([H])C([H])=C(F)C([H])=C1[H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)N1N=C(C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])[C@@]([H])(C2=C([H])SC([H])=C2[H])C1([H])[H])C(C1=C([H])C([H])=C([H])C([H])=C1[H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)N1N=C(C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])[C@]([H])(C2=C([H])C([H])=C([H])C([H])=C2[H])C1([H])[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(C(=O)N1N=C(C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])[C@]([H])(C2=C([H])C([H])=C([H])C([H])=C2[H])C1([H])[H])[C@]1([H])C2=C(C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(C(=O)N1N=C(C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])[C@]([H])(C2=C([H])C([H])=C([H])C([H])=C2[H])C1([H])[H])C1=C([H])C([H])=C([H])C([H])=C1C(F)(F)F
[H]N(C(=O)N1N=C(C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])[C@@]([H])(C2=C([H])C([H])=C([H])C([H])=C2[H])C1([H])[H])C1=C([H])C([H])=C([H])C2=C([H])C([H])=C([H])C([H])=C12
[H]N(C(=O)N1N=C(C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])[C@@]([H])(C2=C([H])C([H])=C([H])C([H])=C2[H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)N1N=C(C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])[C@@]([H])(C2=C([H])C([H])=C([H])C([H])=C2[H])C1([H])[H])C([H])([H])[C@]12C([H])([H])[C@@]3([H])C([H])([H])[C@]([H])(C([H])([H])[C@]([H])(C3([H])[H])C1([H])[H])C2([H])[H]
[H]C1=NN(C([H])=N1)C([H])([H])C1=C(N(N=C1C1=NN=C(S1)C1(C([H])([H])C([H])([H])C1([H])[H])C(F)(F)F)C1=C([H])C([H])=C([H])C([H])=C1C(F)(F)F)C1=C([H])C([H])=C(Br)C([H])=C1[H]
[H]C1=NN(C([H])=N1)C([H])([H])C1=C(N(N=C1C1=NN=C(S1)C1(C([H])([H])C([H])([H])C1([H])[H])C(F)(F)F)C1=C([H])C([H])=C([H])C([H])=C1Cl)C1=C([H])C([H])=C(Br)C([H])=C1[H]
[H]C1=NN(C([H])=N1)C([H])([H])C1=C(N(N=C1C1=NN=C(S1)C1(C([H])([H])C([H])([H])C1([H])[H])C(F)(F)F)C1=C([H])C([H])=C([H])C([H])=C1C(F)(F)F)C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])[C@@]1([H])C(=NN(C(=O)C2=C([H])C([H])=C([H])C3=C([H])C([H])=C([H])C([H])=C23)C1([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]N(C(=O)N1N=C(C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])[C@]([H])(C2=C([H])C([H])=C([H])C([H])=C2[H])C1(C([H])([H])[H])C([H])([H])[H])C(C1=C([H])C([H])=C([H])C([H])=C1[H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)N1N=C(C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])[C@@]([H])(C2=C([H])C([H])=C([H])C([H])=C2[H])C1(C([H])([H])[H])C([H])([H])[H])[C@@]1([H])C([H])([H])[C@@]2([H])C([H])([H])C([H])([H])[C@]1(C([H])([H])[H])C2(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)C1=NN(C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])[C@]([H])(C2=C([H])C([H])=C([H])C([H])=C2[H])C1([H])[H])[C@@]1([H])[C@@]2([H])C([H])([H])[C@]3([H])C([H])([H])[C@]([H])(C2([H])[H])C([H])([H])[C@@]1([H])C3([H])[H]
[H]N(C(=O)C1=NN(C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])[C@]([H])(C2=C([H])C([H])=C([H])C([H])=C2[H])C1([H])[H])C(C1=C([H])C([H])=C(F)C([H])=C1[H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)C1=NN(C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])[C@]([H])(C2=C(F)C([H])=C([H])C([H])=C2[H])C1([H])[H])[C@@]1([H])C([H])([H])[C@@]2([H])C([H])([H])C([H])([H])[C@]1(C([H])([H])[H])C2(C([H])([H])[H])C([H])([H])[H]
[H]OC1=C([H])C(=C([H])C2=C1[C@]1([H])C([H])([H])[C@@]([H])(O[H])C([H])([H])C([H])([H])[C@@]1([H])C(O2)(C([H])([H])[H])C([H])([H])[H])C(=O)N([H])[C@@]1([H])[C@@]2([H])C([H])([H])[C@]3([H])C([H])([H])[C@]([H])(C2([H])[H])C([H])([H])[C@@]1([H])C3([H])[H]
[H]OC1=C([H])C(=C([H])C2=C1[C@]1([H])C([H])([H])[C@]([H])(O[H])C([H])([H])C([H])([H])[C@@]1([H])C(O2)(C([H])([H])[H])C([H])([H])[H])[C@@]12O[C@]3([H])C([H])([H])[C@@]([H])(C([H])([H])[C@@]([H])(C3([H])[H])C1([H])[H])C2([H])[H]
[H]OC([H])([H])C([H])([H])C(=O)N([H])[C@@]1([H])C2=C([H])C(C3=C([H])C([H])=C(Cl)C([H])=C3[H])=C(N=C2OC(C([H])([H])[H])(C([H])([H])[H])C1([H])[H])C1=C([H])C([H])=C(Cl)C([H])=C1Cl
[H]OC1=C([H])C(=C([H])C2=C1[C@]1([H])C([H])([H])[C@@]([H])(O[H])C([H])([H])C([H])([H])[C@@]1([H])C(O2)(C([H])([H])[H])C([H])([H])[H])N1[C@@]2([H])C([H])([H])[C@]3([H])O[C@@]([H])(C([H])([H])[C@@]1([H])C3([H])[H])C2([H])[H]
[H]OC([H])([H])C(N([H])C(=O)[C@@]1([H])C2=C([H])C(C3=C([H])C([H])=C(Cl)C([H])=C3[H])=C(N=C2OC(C([H])([H])[H])(C([H])([H])[H])C1([H])[H])C1=C([H])C([H])=C(Cl)C([H])=C1Cl)(C([H])([H])[H])C([H])([H])[H]
CC1=C(C)N(CCO[11CH3])\C(S1)=N\C(=O)C1C(C)(C)C1(C)C
[H]N(C(=O)N1N=C(C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])[C@@]([H])(C2=C([H])C([H])=C([H])C([H])=C2[H])C1([H])[H])[C@]12C([H])([H])[C@@]3([H])C([H])([H])[C@]([H])(C([H])([H])[C@]([H])(C3([H])[H])C1([H])[H])C2([H])[H]
[H]C1=NN(C([H])=N1)C([H])([H])C1=C(N(N=C1C1=NN=C(S1)C1(C([H])([H])C1([H])[H])C(F)(F)F)C1=C([H])C([H])=C([H])C([H])=C1Cl)C1=C([H])C([H])=C(Br)C([H])=C1[H]
[H]C1=NN(C([H])=N1)C([H])([H])C1=C(N(N=C1C1=NN=C(S1)C1(C2=C([H])C([H])=C(Cl)C([H])=C2[H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C([H])C([H])=C1Cl)C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]C1=NN(C([H])=N1)C([H])([H])C1=C(N(N=C1C1=NN=C(S1)C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C(Cl)C([H])=C1Cl)C1=C([H])C([H])=C(Br)C([H])=C1[H]
[H]C1=NN(C([H])=N1)C([H])([H])C1=C(N(N=C1C1=NN=C(S1)C1(C([H])([H])C([H])([H])C1([H])[H])C(F)(F)F)C1=C([H])C([H])=C(Cl)C([H])=C1Cl)C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]C1=NN(C([H])=N1)C([H])([H])C1=C(N(N=C1C1=NN=C(S1)C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1Cl)C1=C([H])C([H])=C(Br)C([H])=C1[H]
[H]C1=NN(C([H])=N1)C([H])([H])C1=C(N(N=C1C1=NN=C(S1)C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C(Cl)C([H])=C1Cl)C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]C1=NN(C([H])=N1)C([H])([H])C1=C(N(N=C1C1=NN=C(S1)C1(C([H])([H])C1([H])[H])C(F)(F)F)C1=C([H])C([H])=C(Cl)C([H])=C1Cl)C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]O[C@]1([H])C([H])([H])C([H])([H])C([H])([H])[C@]([H])(C2=C([H])C([H])=C(C([H])=C2OC([H])([H])[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C1([H])[H]
[H]OC(C(=O)N([H])[C@@]1([H])C2=C([H])C(C3=C([H])C([H])=C(Cl)C([H])=C3[H])=C(N=C2O[C@]2(C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C1([H])[H])C1=C([H])C([H])=C([H])C([H])=C1Cl)(C([H])([H])[H])C([H])([H])[H]
[H]O[C@]1([H])C([H])([H])C([H])([H])C([H])([H])[C@]([H])(C2=C([H])C([H])=C(C([H])=C2[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C1([H])[H]
[H][C@@]12CC(=O)CC[C@@]1([H])C(C)(C)OC1=C2C(O)=CC(=C1)C1(CCCC1)\C=C/CCCC
[H][C@@]12CC(=O)CC[C@@]1([H])C(C)(C)OC1=C2C(O)=CC(=C1)C1(CCCCCC)CCCC1
[H][C@@]12CC(=O)CC[C@@]1([H])C(C)(C)OC1=C2C(O)=CC(=C1)C1(CCCCCC)SCCS1
[H][C@@]12CC(=O)CC[C@@]1([H])C(C)(C)OC1=C2C(O)=CC(=C1)C1(CCC1)\C=C/CCCC
[H][C@@]12CC(=O)CC[C@@]1([H])C(C)(C)OC1=C2C(O)=CC(=C1)C1(CCCCCBr)CCCC1
[H][C@@]12C[C@H](O)CC[C@@]1([H])C(C)(C)OC1=C2C(O)=CC(=C1)C1(CCCCCC)CCC1
[H][C@@]12C[C@H](O)CC[C@@]1([H])C(C)(C)OC1=C2C(O)=CC(=C1)C1(CCCCCBr)CCC1
[H]C1=C(Br)C2=C(OC(C([H])([H])[H])(C([H])([H])[H])[C@]3([H])C([H])([H])C([H])=C(C([H])([H])[H])C([H])([H])[C@@]23[H])C([H])=C1C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]C1=C(Br)C2=C(OC(C([H])([H])[H])(C([H])([H])[H])[C@]3([H])C([H])([H])C([H])=C(C([H])([H])[H])C([H])([H])[C@@]23[H])C([H])=C1C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]C1=C(Br)C2=C(OC(C([H])([H])[H])(C([H])([H])[H])[C@]3([H])C([H])([H])C([H])=C(C([H])([H])[H])C([H])([H])[C@@]23[H])C([H])=C1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
COC1(CNS(=O)(=O)C(F)(F)F)CCN(CC1)S(=O)(=O)C1=CC2=CC=CN=C2N1S(=O)(=O)C1=C(F)C=CC=C1
CCCC1(CNS(=O)(=O)C(F)(F)F)CCN(CC1)S(=O)(=O)C1=CC2=CC=CC=C2N1S(=O)(=O)C1=NC=CC=C1
CCC1(CNS(=O)(=O)C(F)(F)F)CCN(CC1)S(=O)(=O)C1=CC2=CC(F)=CC=C2N1S(=O)(=O)C1=C(F)C=CC=C1
FC(F)(F)S(=O)(=O)N[C@H]1CC11CCN(CC1)S(=O)(=O)C1=CC2=CC=CC=C2N1S(=O)(=O)C1=NC=CC=C1
CN(C)C1=C(C=CC=N1)S(=O)(=O)N1C2=CC=CC=C2C=C1S(=O)(=O)N1CCC(CNS(=O)(=O)C(F)(F)F)CC1
FC(F)(F)S(=O)(=O)NCC1CCN(CC1)S(=O)(=O)C1=CC2=CC=CC=C2N1S(=O)(=O)C1=CN=CC=C1
FC(F)(F)S(=O)(=O)NCC1CCN(CC1)S(=O)(=O)C1=CC2=CC=CC=C2N1S(=O)(=O)C1=NC=CC=C1
FC1=C(C=CC=C1)S(=O)(=O)C1=C(C=CC=N1)S(=O)(=O)N1CCC(CNS(=O)(=O)C(F)(F)F)CC1
FC1=C(C=CC=C1)S(=O)(=O)C1=C(C=CO1)S(=O)(=O)N1CCC(CNS(=O)(=O)C(F)(F)F)CC1
CN1C2=C(C=CC=C2)C(=C1S(=O)(=O)C1=C(F)C=CC=C1)S(=O)(=O)N1CCC(CNS(=O)(=O)C(F)(F)F)CC1
COC1=CC=C2N(C(=CC2=C1)S(=O)(=O)N1CCC(CNS(=O)(=O)C(F)(F)F)CC1)S(=O)(=O)C1=C(F)C=CC=C1
[H][C@@]12CN(C[C@]1([H])[C@H]2CNS(=O)(=O)C(F)(F)F)S(=O)(=O)C1=CC2=CC=CC=C2N1S(=O)(=O)C1=C(F)C=CC=C1
FC1=C(C=CC=C1)S(=O)(=O)N1C2=CC=CC=C2C=C1S(=O)(=O)N1CCC2(C[C@@H]2NS(=O)(=O)C(F)(F)F)CC1
CC[C@]1(CNS(=O)(=O)C(F)(F)F)CCN(C[C@H]1C)S(=O)(=O)C1=CC2=CC=CC=C2N1S(=O)(=O)C1=C(F)C=CC=C1
C[C@H]1C[C@H](CNS(=O)(=O)C(F)(F)F)CCN1S(=O)(=O)C1=CC2=CC=CC=C2N1S(=O)(=O)C1=C(F)C=CC=C1
CC(C)C1(CNS(=O)(=O)C(F)(F)F)CCCN(C1)S(=O)(=O)C1=CC2=CC=CC=C2N1S(=O)(=O)C1=C(F)C=CC=C1
CCCC1(CNS(=O)(=O)C(F)(F)F)CCN(CC1)S(=O)(=O)C1=CC2=CC=CC=C2N1S(=O)(=O)C1=C(F)C=CC=C1
CC1(CNS(=O)(=O)C(F)(F)F)CCN(CC1)S(=O)(=O)C1=CC2=CC=CC=C2N1S(=O)(=O)C1=C(F)C=CC=C1
OC1(CNS(=O)(=O)C(F)(F)F)CCN(CC1)S(=O)(=O)C1=CC2=CC=CC=C2N1S(=O)(=O)C1=C(F)C=CC=C1
CC(C)(NS(=O)(=O)C(F)(F)F)C1CCN(CC1)S(=O)(=O)C1=CC2=CC=CC=C2N1S(=O)(=O)C1=C(F)C=CC=C1
FC1=C(C=CC=C1)S(=O)(=O)N1C(=CC2=CC=CC=C12)S(=O)(=O)N1CC(CCNS(=O)(=O)C(F)(F)F)C1
FC1=C(C=CC=C1)S(=O)(=O)N1C2=CC=CC=C2C=C1S(=O)(=O)N1CCC2(CC(C2)NS(=O)(=O)C(F)(F)F)C1
FC1=C(C=CC=C1)S(=O)(=O)N1C(=CC2=CC=CC=C12)S(=O)(=O)N1CCCC(CCNS(=O)(=O)C(F)(F)F)C1
C[C@@H](NS(=O)(=O)C(F)(F)F)C1=CC=C(C=C1)S(=O)(=O)C1=C(OC=C1)S(=O)(=O)C1=C(F)C=CC=C1
C[C@@H](NS(=O)(=O)C(F)(F)F)C1=CC=C(C=C1)S(=O)(=O)N1C=CC=C1S(=O)(=O)C1=C(F)C=CC=C1
C[C@@H](NS(=O)(=O)C(F)(F)F)C1=CC=C(C=C1)S(=O)(=O)C1=CC2=CC=CC=C2N1S(=O)(=O)C1=C(F)C=CC=C1
C[C@@H](NS(=O)(=O)C(F)(F)F)C1=CC=C(C=C1)S(=O)(=O)C1=C(C=C(Cl)C=C1)S(=O)(=O)C1=C(F)C=CC=C1
[H]OC([H])([H])C1=C([H])C([H])([H])[C@]2([H])[C@]([H])(C3=C(OC2(C([H])([H])[H])C([H])([H])[H])C([H])=C(C([H])=C3[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C1([H])[H]
CN(CCCCCCCCCCCN)CCCCCCCCCCCNC(=O)C1=NN(C(=C1C)C1=CC=C(Cl)C=C1)C1=C(Cl)C=C(Cl)C=C1
CN(CCCCCN)CCCCCNC(=O)C1=NN(C(=C1C)C1=CC=C(Cl)C=C1)C1=C(Cl)C=C(Cl)C=C1
CC1=C(N(N=C1C(=O)NCCCNCCCN)C1=C(Cl)C=C(Cl)C=C1)C1=CC=C(Cl)C=C1
CC1=C(N(N=C1C(=O)NCCNCCN)C1=C(Cl)C=C(Cl)C=C1)C1=CC=C(Cl)C=C1
[H]N(C(=O)C1=NN(C(N2C([H])=C([H])C([H])=C2[H])=C1C([H])([H])[H])C1=C(Cl)C([H])=C(Cl)C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]N(C(=O)C1=NN(C(N2C([H])=C([H])C([H])=C2[H])=C1C([H])([H])[H])C1=C(Cl)C([H])=C(Cl)C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]OC([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=O)C1=NN(C(N2C([H])=C([H])C([H])=C2[H])=C1C([H])([H])[H])C1=C(Cl)C([H])=C(Cl)C([H])=C1[H]
[H]N(C(=O)C1=NN(C(N2C(=C([H])C([H])=C2C([H])([H])[H])C([H])([H])[H])=C1C([H])([H])[H])C1=C(Cl)C([H])=C(Cl)C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]N(C(=O)C1=NN(C(N2C(=C([H])C([H])=C2C([H])([H])[H])C([H])([H])[H])=C1C([H])([H])[H])C1=C(Cl)C([H])=C(Cl)C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]OC([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=O)C1=NN(C(N2C(=C([H])C([H])=C2C([H])([H])[H])C([H])([H])[H])=C1C([H])([H])[H])C1=C(Cl)C([H])=C(Cl)C([H])=C1[H]
[H]N(C(=O)C1=NN(C(N2C([H])=C([H])C([H])=C2[H])=C1C([H])([H])[H])C1=C(Cl)C([H])=C(Cl)C([H])=C1[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)C1=NN(C(N2C([H])=C([H])C([H])=C2[H])=C1C([H])([H])[H])C1=C(Cl)C([H])=C(Cl)C([H])=C1[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)C1=NN(C(N2C([H])=C([H])C([H])=C2[H])=C1C([H])([H])[H])C1=C(Cl)C([H])=C(Cl)C([H])=C1[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C([H])([H])[H]
[H]N(C(=O)C1=NN(C(N2C([H])=C([H])C([H])=C2[H])=C1C([H])([H])[H])C1=C(Cl)C([H])=C(Cl)C([H])=C1[H])C([H])([H])C([H])([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)C1=NN(C(N2C(=C([H])C([H])=C2C([H])([H])[H])C([H])([H])[H])=C1C([H])([H])[H])C1=C(Cl)C([H])=C(Cl)C([H])=C1[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)C1=NN(C(N2C(=C([H])C([H])=C2C([H])([H])[H])C([H])([H])[H])=C1C([H])([H])[H])C1=C(Cl)C([H])=C(Cl)C([H])=C1[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)C1=NN(C(N2C(=C([H])C([H])=C2C([H])([H])[H])C([H])([H])[H])=C1C([H])([H])[H])C1=C(Cl)C([H])=C(Cl)C([H])=C1[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C([H])([H])[H]
[H]N(C(=O)C1=NN(C(N2C(=C([H])C([H])=C2C([H])([H])[H])C([H])([H])[H])=C1C([H])([H])[H])C1=C(Cl)C([H])=C(Cl)C([H])=C1[H])C([H])([H])C([H])([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)C1=NN(C(N2C(=C([H])C([H])=C2C([H])([H])[H])C([H])([H])[H])=C1C([H])([H])[H])C1=C(F)C([H])=C(F)C([H])=C1[H])C([H])([H])C([H])([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]N1N([H])C(=C(\C1=C1/C([H])=C([H])C(OC([H])([H])[H])=C([H])C1=O)C1=C([H])C([H])=C(Cl)C([H])=C1[H])C([H])([H])[H]
[H]N1C([H])=C(N=C1C1=C([H])C(=C([H])C([H])=C1[H])C([H])([H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C1=C([H])C([H])=C([H])C(=C1[H])C(F)(F)F
[H]C1=C(N=C(N1C([H])(C([H])([H])[H])C([H])([H])[H])C1=C([H])C(=C([H])C([H])=C1[H])C([H])([H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C1=C([H])C([H])=C([H])C(=C1[H])C(F)(F)F
[H]C1=C(N=C(N1C([H])([H])C1([H])C([H])([H])C1([H])[H])C1=C([H])C(=C([H])C([H])=C1[H])C([H])([H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C1=C([H])C([H])=C([H])C(=C1[H])C(F)(F)F
[H]C1=C(N=C(N1C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C(=C([H])C([H])=C1[H])C([H])([H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C1=C([H])C([H])=C([H])C(=C1[H])C(F)(F)F
[H]C1=C(N=C(N1C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C(=C([H])C([H])=C1[H])C([H])([H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C1=C([H])C([H])=C([H])C(=C1[H])C(F)(F)F
[H]C1=C(N=C(N1C(=O)C([H])([H])[H])C1=C([H])C(=C([H])C([H])=C1[H])C([H])([H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C1=C([H])C([H])=C([H])C(=C1[H])C(F)(F)F
[H]C1=C(N=C(N1C(=O)C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C(=C([H])C([H])=C1[H])C([H])([H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C1=C([H])C([H])=C([H])C(=C1[H])C(F)(F)F
[H]C1=C(N=C(N1S(=O)(=O)C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C(=C([H])C([H])=C1[H])C([H])([H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C1=C([H])C([H])=C([H])C(=C1[H])C(F)(F)F
[H]N1C([H])=C(N=C1C1=C([H])C(=C([H])C([H])=C1[H])C([H])([H])N1C([H])([H])C([H])([H])SC([H])([H])C1([H])[H])C1=C([H])C([H])=C([H])C(=C1[H])C(F)(F)F
[H]N1C([H])=C(N=C1C1=C([H])C(=C([H])C([H])=C1[H])C([H])([H])N1C([H])([H])C([H])([H])O[C@]([H])(C([H])([H])[H])C1([H])[H])C1=C([H])C([H])=C([H])C(=C1[H])C(F)(F)F
[H]N1C([H])=C(N=C1C1=C([H])C(=C([H])C([H])=C1[H])C([H])([H])N1C([H])([H])C([H])([H])OC([H])([H])[C@]1([H])C([H])([H])[H])C1=C([H])C([H])=C([H])C(=C1[H])C(F)(F)F
[H]N1C([H])=C(N=C1C1=C([H])C(=C([H])C([H])=C1[H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C([H])C(=C1[H])C(F)(F)F
[H]N1C([H])=C(N=C1C1=C([H])C(=C([H])C([H])=C1[H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])[C@]([H])(C([H])([H])[H])C1([H])[H])C1=C([H])C([H])=C([H])C(=C1[H])C(F)(F)F
[H]N1C([H])=C(N=C1C1=C([H])C(=C([H])C([H])=C1[H])C([H])([H])N1C([H])([H])C([H])([H])C([H])(F)C([H])([H])C1([H])[H])C1=C([H])C([H])=C([H])C(=C1[H])C(F)(F)F
[H]N1C([H])=C(N=C1C1=C([H])C(=C([H])C([H])=C1[H])C([H])([H])N1C([H])([H])C([H])([H])C(F)(F)C([H])([H])C1([H])[H])C1=C([H])C([H])=C([H])C(=C1[H])C(F)(F)F
[H]N1C([H])=C(N=C1C1=C([H])C(=C([H])C([H])=C1[H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])[C@]([H])(F)C1([H])[H])C1=C([H])C([H])=C([H])C(=C1[H])C(F)(F)F
[H]O[C@]1([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C([H])C(=C2[H])C2=NC(=C([H])N2[H])C2=C([H])C([H])=C([H])C(=C2[H])C(F)(F)F)C([H])([H])C([H])([H])C1([H])[H]
[H]OC([H])([H])[C@@]1([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C([H])C(=C2[H])C2=NC(=C([H])N2[H])C2=C([H])C([H])=C([H])C(=C2[H])C(F)(F)F)C([H])([H])C([H])([H])C1([H])[H]
[H]N1C([H])=C(N=C1C1=C([H])C(=C([H])C([H])=C1[H])C([H])([H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C1=C([H])C([H])=C([H])C(Br)=C1[H]
[H]N1C([H])=C(N=C1C1=C([H])C(=C([H])C([H])=C1[H])C([H])([H])N1C([H])([H])C([H])([H])O[C@]([H])(C([H])([H])[H])C1([H])[H])C1=C([H])C([H])=C([H])C(Cl)=C1[H]
[H]N1C([H])=C(N=C1C1=C([H])C(=C([H])C([H])=C1[H])C([H])([H])N1C([H])([H])C([H])([H])C([H])(F)C([H])([H])C1([H])[H])C1=C([H])C([H])=C([H])C(Cl)=C1[H]
[H]N1C([H])=C(N=C1C1=C([H])C(=C([H])C([H])=C1[H])C([H])([H])N1C([H])([H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C([H])C(Cl)=C1Cl
[H]N(C(=O)C1=C([H])N(C(=C([H])C1=O)C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])[C@]12C([H])([H])[C@@]3([H])C([H])([H])[C@]([H])(C([H])([H])[C@]([H])(C3([H])[H])C1([H])[H])C2([H])[H]
[H]N(C(=O)C1=C([H])N(C(=C([H])C1=O)C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])[C@]12C([H])([H])[C@@]3([H])C([H])([H])[C@]([H])(C([H])([H])[C@]([H])(C3([H])[H])C1([H])[H])C2([H])[H]
[H]N(C(=O)C1=C([H])N(C(=C([H])C1=O)C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(C(=O)C1=C([H])N(C(=C([H])C1=O)C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])[H])[C@@]([H])(C([H])([H])[H])[C@]12C([H])([H])[C@@]3([H])C([H])([H])[C@]([H])(C([H])([H])[C@]([H])(C3([H])[H])C1([H])[H])C2([H])[H]
[H]N(C(=O)C1=C([H])N(C(=C([H])C1=O)C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])[C@@]([H])(C([H])([H])[H])[C@]12C([H])([H])[C@@]3([H])C([H])([H])[C@]([H])(C([H])([H])[C@]([H])(C3([H])[H])C1([H])[H])C2([H])[H]
[H]N(C(=O)C1=C([H])N(C2=C([H])C([H])=C([H])C([H])=C2[H])C(=C([H])C1=O)C1=C([H])C([H])=C([H])C([H])=C1[H])[C@@]([H])(C([H])([H])[H])[C@]12C([H])([H])[C@@]3([H])C([H])([H])[C@]([H])(C([H])([H])[C@]([H])(C3([H])[H])C1([H])[H])C2([H])[H]
[H]N(C(=O)C1=C([H])N(C(=C([H])C1=O)C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])[C@]12C([H])([H])[C@@]3([H])C([H])([H])[C@]([H])(C([H])([H])[C@]([H])(C3([H])[H])C1([H])[H])C2([H])[H]
[H]N(C(=O)C1=C([H])N(C(=C([H])C1=O)C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])[C@]12C([H])([H])[C@@]3([H])C([H])([H])[C@]([H])(C([H])([H])[C@]([H])(C3([H])[H])C1([H])[H])C2([H])[H]
[H]N(C(=O)C1=C([H])N(C(=C([H])C1=O)C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(C(=O)C1=C([H])N(C(=C([H])C1=O)C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])[C@@]1([H])C2=C(C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C1([H])[H]
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[H]N(C(=O)C1=C([H])N(C(=C([H])C1=O)C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C1=C([H])C(=C([H])C([H])=C1[H])C(F)(F)F
[H]N(C(=O)C1=C([H])N(C(=C([H])C1=O)C1=C([H])C([H])=C(Cl)C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])[C@]12C([H])([H])[C@@]3([H])C([H])([H])[C@]([H])(C([H])([H])[C@]([H])(C3([H])[H])C1([H])[H])C2([H])[H]
[H]N(C(=O)C1=C([H])N(C(=C([H])C1=O)C1=C([H])C([H])=C(Cl)C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(C(=O)C1=C([H])N(C(=C([H])C1=O)C1=C([H])C([H])=C(Cl)C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C1=C([H])C(=C([H])C([H])=C1[H])C(F)(F)F
[H]N(C(=O)C1=C([H])N(C(=C([H])C1=O)C1=C([H])C(Cl)=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])[C@]12C([H])([H])[C@@]3([H])C([H])([H])[C@]([H])(C([H])([H])[C@]([H])(C3([H])[H])C1([H])[H])C2([H])[H]
[H]N(C(=O)C1=C([H])N(C(=C([H])C1=O)C1=C(Cl)C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])[C@]12C([H])([H])[C@@]3([H])C([H])([H])[C@]([H])(C([H])([H])[C@]([H])(C3([H])[H])C1([H])[H])C2([H])[H]
[H]N(C(=O)C1=C([H])N(C(=C([H])C1=O)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])[C@]12C([H])([H])[C@@]3([H])C([H])([H])[C@]([H])(C([H])([H])[C@]([H])(C3([H])[H])C1([H])[H])C2([H])[H]
[H]N(C(=O)C1=C([H])N(C(=C([H])C1=O)C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])[C@]12C([H])([H])[C@@]3([H])C([H])([H])[C@]([H])(C([H])([H])[C@]([H])(C3([H])[H])C1([H])[H])C2([H])[H]
[H]N(C(=O)C1=C([H])N(C(=C([H])C1=S)C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])[C@]12C([H])([H])[C@@]3([H])C([H])([H])[C@]([H])(C([H])([H])[C@]([H])(C3([H])[H])C1([H])[H])C2([H])[H]
[H]N(C(=O)C1=C([H])N(C(=C([H])C1=S)C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(C(=O)OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C1=C([H])N(C(=C([H])C1=O)C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]N(C(=O)C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C1=C([H])N(C(=C([H])C1=O)C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]OC1=C([H])C([H])([H])[C@]2([H])[C@]([H])(C3=C([H])C([H])=C(C([H])=C3OC2(C([H])([H])[H])C([H])([H])[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[H])C1([H])[H]
[H]N1C([H])=C(N=C1C1=C([H])C(=C([H])C([H])=C1[H])C([H])([H])N1C([H])([H])C([H])([H])C([H])(F)C([H])([H])C1([H])[H])C1=C([H])C([H])=C([H])C(Cl)=C1Cl
[H]N1C([H])=C(N=C1C1=C([H])C(=C([H])C([H])=C1[H])C([H])([H])N1C([H])([H])C([H])([H])C([H])(F)C([H])([H])C1([H])[H])C1=C([H])C([H])=C(Cl)C([H])=C1Cl
[H]N1C([H])=C(N=C1C1=C([H])C(=C([H])C([H])=C1[H])C([H])([H])N1C([H])([H])C([H])([H])C(F)(F)C([H])([H])C1([H])[H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1F
[H]N1C([H])=C(N=C1C1=C([H])C(=C([H])C([H])=C1[H])C([H])([H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C1=C([H])C(OC([H])([H])[H])=C([H])C([H])=C1F
[H]N1C([H])=C(N=C1C1=C([H])C(=C([H])C([H])=C1[H])C([H])([H])N1C([H])([H])C([H])([H])C(F)(F)C([H])([H])C1([H])[H])C1=C([H])C(OC([H])([H])[H])=C([H])C([H])=C1F
[H]N1C([H])=C(N=C1C1=C([H])C(=C([H])C([H])=C1[H])C([H])([H])N1C([H])([H])C([H])([H])C([H])(F)C([H])([H])C1([H])[H])C1=C([H])C(OC([H])([H])[H])=C([H])C([H])=C1F
[H]N1C([H])=C(N=C1C1=C(C([H])=C([H])C([H])=C1[H])C([H])([H])N1C([H])([H])C([H])([H])C([H])(F)C([H])([H])C1([H])[H])C1=C([H])C([H])=C([H])C(=C1[H])C(F)(F)F
[H]N1C([H])=C(N=C1C1=C(C([H])=C([H])C([H])=C1[H])C([H])([H])N1C([H])([H])C([H])([H])O[C@]([H])(C([H])([H])[H])C1([H])[H])C1=C([H])C([H])=C([H])C(=C1[H])C(F)(F)F
[H]N1C([H])=C(N=C1C1=C([H])C(=C([H])C([H])=C1[H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C([H])C(Cl)=C1[H]
[H]C1=C([H])C(=NC(=C1[H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1C(=O)N(C(=O)C1([H])[H])C1([H])C([H])([H])C([H])([H])C1([H])[H]
[H]C1=C([H])C(=NC(=C1[H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1C(=O)N(C(=O)C1([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])C(=NC(=C1[H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1C(=O)N(C(=O)C1([H])[H])C([H])([H])[H]
[H]C1=C([H])C(=NC(=C1[H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1C(=O)N(C(=O)C1([H])[H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]C1=C([H])C(=NC(=C1F)C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])C(F)(F)C1([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1C(=O)N(C(=O)C1([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])C(=NC(=C1[H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1C(=O)N(C(=O)C1([H])[H])C([H])([H])C([H])(F)F
[H]C1=C([H])C(=C([H])C([H])=C1Br)C(=O)\N=C1/SC(=C(N1C([H])([H])C1([H])C([H])([H])C1([H])[H])C([H])([H])[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])C(=C([H])C([H])=C1OC(F)(F)F)C(=O)\N=C1/SC(=C(N1C([H])([H])C1([H])C([H])([H])C1([H])[H])C([H])([H])[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])C(=C([H])C([H])=C1C(=O)\N=C1/SC(=C(N1C([H])([H])C([H])([H])OC([H])([H])[H])C([H])([H])[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C(F)(F)F
[H]N(C(=O)C1=C([H])N(C2=C([H])C([H])=C(I)C([H])=C2C1=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])[C@]12C([H])([H])[C@@]3([H])C([H])([H])[C@]([H])(C([H])([H])[C@]([H])(C3([H])[H])C1([H])[H])C2([H])[H]
[H]N(C(=O)C1=C([H])N(C2=C([H])C([H])=C(C([H])=C2C1=O)C1=C([H])C([H])=C([H])O1)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])[C@]12C([H])([H])[C@@]3([H])C([H])([H])[C@]([H])(C([H])([H])[C@]([H])(C3([H])[H])C1([H])[H])C2([H])[H]
[H]N(C(=O)C1=C([H])N(C2=C([H])C([H])=C(C([H])=C2C1=O)C1=C([H])C([H])=C([H])S1)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])[C@]12C([H])([H])[C@@]3([H])C([H])([H])[C@]([H])(C([H])([H])[C@]([H])(C3([H])[H])C1([H])[H])C2([H])[H]
[H]OC1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C2N(C([H])=C(C(=O)N([H])[C@]34C([H])([H])[C@@]5([H])C([H])([H])[C@]([H])(C([H])([H])[C@]([H])(C5([H])[H])C3([H])[H])C4([H])[H])C(=O)C2=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]N(C(=O)C1=C([H])N(C2=C([H])C([H])=C(C([H])=C2C1=O)C1=C([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])[C@]12C([H])([H])[C@@]3([H])C([H])([H])[C@]([H])(C([H])([H])[C@]([H])(C3([H])[H])C1([H])[H])C2([H])[H]
[H]N(C(=O)C1=C([H])N(C2=C([H])C([H])=C(C([H])=C2C1=O)C1=C([H])C([H])=C(Cl)C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])[C@]12C([H])([H])[C@@]3([H])C([H])([H])[C@]([H])(C([H])([H])[C@]([H])(C3([H])[H])C1([H])[H])C2([H])[H]
[H]N(C(=O)C1=C([H])N(C2=C([H])C([H])=C(C([H])=C2C1=O)C1=C(F)C([H])=C(F)C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])[C@]12C([H])([H])[C@@]3([H])C([H])([H])[C@]([H])(C([H])([H])[C@]([H])(C3([H])[H])C1([H])[H])C2([H])[H]
[H]N(C(=O)C1=C([H])N(C2=C([H])C([H])=C(C([H])=C2C1=O)C1=C([H])C([H])=C(Cl)S1)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])[C@]12C([H])([H])[C@@]3([H])C([H])([H])[C@]([H])(C([H])([H])[C@]([H])(C3([H])[H])C1([H])[H])C2([H])[H]
[H]N(C(=O)C1=C([H])N(C2=C([H])C([H])=C(C([H])=C2C1=O)C1=C([H])C([H])=C(C#N)C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])[C@]12C([H])([H])[C@@]3([H])C([H])([H])[C@]([H])(C([H])([H])[C@]([H])(C3([H])[H])C1([H])[H])C2([H])[H]
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[H]C#CC1=C([H])C([H])=C2N(C([H])=C(C(=O)N([H])[C@]34C([H])([H])[C@@]5([H])C([H])([H])[C@]([H])(C([H])([H])[C@]([H])(C5([H])[H])C3([H])[H])C4([H])[H])C(=O)C2=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]N(C(=O)C1=C([H])N(C2=C([H])C([H])=C(C([H])=C2C1=O)N1C([H])=NC([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])[C@]12C([H])([H])[C@@]3([H])C([H])([H])[C@]([H])(C([H])([H])[C@]([H])(C3([H])[H])C1([H])[H])C2([H])[H]
[H]N(C(=O)C1=C([H])N(C2=C([H])C([H])=C(C([H])=C2C1=O)C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])[C@]12C([H])([H])[C@@]3([H])C([H])([H])[C@]([H])(C([H])([H])[C@]([H])(C3([H])[H])C1([H])[H])C2([H])[H]
[H]N(C(=O)C1=C([H])N(C2=C([H])C([H])=C(C([H])=C2C1=O)C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])[C@]12C([H])([H])[C@@]3([H])C([H])([H])[C@]([H])(C([H])([H])[C@]([H])(C3([H])[H])C1([H])[H])C2([H])[H]
[H]C#CC([H])([H])N1C([H])=C(C(=O)N([H])[C@]23C([H])([H])[C@@]4([H])C([H])([H])[C@]([H])(C([H])([H])[C@]([H])(C4([H])[H])C2([H])[H])C3([H])[H])C(=O)C2=C([H])C(Br)=C([H])C([H])=C12
[H]C([H])=C([H])C([H])([H])C([H])([H])N1C([H])=C(C(=O)N([H])[C@]23C([H])([H])[C@@]4([H])C([H])([H])[C@]([H])(C([H])([H])[C@]([H])(C4([H])[H])C2([H])[H])C3([H])[H])C(=O)C2=C([H])C(=C([H])C([H])=C12)C1=C([H])C([H])=C([H])O1
[H]C1=C(OC(=O)C([H])([H])C([H])([H])C([H])([H])N2C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])C2=C(OC(C([H])([H])[H])(C([H])([H])[H])[C@]3([H])C([H])([H])C([H])=C(C([H])([H])[H])C([H])([H])[C@@]23[H])C([H])=C1C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C#N
[H]OC1=C2C(=C([H])C3=C1[C@]1([H])C([H])([H])C(=C([H])C([H])([H])[C@@]1([H])C(O3)(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])[C@]([H])(C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C2([H])[H]
[H]C1=C([H])C(O[S+]([O-])(=O)C([H])([H])C([H])([H])C([H])([H])C(F)(F)F)=C([H])C(OC2=C([H])C([H])=C([H])C(=C2C#N)C(F)(F)F)=C1[H]
[H]N(N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C(=O)C1=NN(C2=C1C([H])([H])C1=C2C([H])=C([H])C(=C1[H])C([H])([H])[H])C1=C([H])C([H])=C(Cl)C([H])=C1Cl
[H]N(C(=O)C1=C([H])N(C2=C([H])C([H])=C(C([H])=C2C1=O)C1=C([H])C([H])=C([H])O1)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])[C@]1([H])C(C([H])([H])[H])(C([H])([H])[H])[C@]2([H])C([H])([H])C([H])([H])[C@@]1(C([H])([H])[H])C2([H])[H]
[H]N(C(=O)C1=C([H])N(C2=C(C([H])=C([H])C([H])=C2C1=O)C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])[C@]12C([H])([H])[C@@]3([H])C([H])([H])[C@]([H])(C([H])([H])[C@]([H])(C3([H])[H])C1([H])[H])C2([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[C@@]1(C2=C([H])C([H])=C(C([H])=C2OC1([H])[H])C(=O)N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])[H]
[H]C1=C([H])C([H])=C2C(C([H])=C([H])C([H])=C2S(=O)(=O)\N=C2/SC(=C(N2C2([H])C([H])([H])C2([H])[H])C([H])([H])[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])=C1[H]
[H]N(C(=O)C1=C([H])N(C2=C(C([H])=C([H])C(=N2)C([H])([H])[H])C1=O)C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(C(=O)C1=C([H])N(C2=C(C([H])=C([H])C(=N2)C([H])([H])[H])C1=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]C1=C([H])C2=C(C([H])=C1[H])C(C(=O)C1=C3C([H])=C(C([H])=C([H])C3=C(C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])[H])=C(N2C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)C1=C([H])N([H])C2=C(OC([H])([H])[H])C([H])=C([H])C(OC([H])([H])[H])=C2C1=O)[C@]12C([H])([H])[C@@]3([H])C([H])([H])[C@]([H])(C([H])([H])[C@]([H])(C3([H])[H])C1([H])[H])C2([H])[H]
[H]N(C(=O)C1=C([H])N([H])C2=C(C(Cl)=C([H])C([H])=C2C1=O)C([H])([H])[H])[C@]12C([H])([H])[C@@]3([H])C([H])([H])[C@]([H])(C([H])([H])[C@]([H])(C3([H])[H])C1([H])[H])C2([H])[H]
[H]C1=C(C(=O)C2([H])C(C([H])([H])[H])(C([H])([H])[H])C2(C([H])([H])[H])C([H])([H])[H])C2=C(N1C([H])([H])C1([H])C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C(=C([H])C([H])=C2[H])C([H])([H])OC1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C1=C([H])C2=C(C([H])=C1[H])C(C(=O)C1=C3C([H])=C([H])C([H])=C([H])C3=C(C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])[H])=C(N2C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])C2=C(C([H])=C1[H])C(C(=O)C1=C([H])C([H])=C([H])C3=C1C([H])=C([H])C([H])=C3[H])=C(N2C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])[H]
[H]C1=C(C(=C(C([H])=C1C([H])([H])C(=O)C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C([H])([H])[H])S(=O)(=O)N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])[H])C([H])([H])[H]
[H]C1=C(C(=C(C([H])=C1C([H])([H])C(=O)C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C([H])([H])[H])S(=O)(=O)N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)C1=C(N(C(=N1)C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H])C1=C(C([H])=C([H])C([H])=C1[H])C(F)(F)F
[H]N1C([H])=C(N=C1C1=C([H])C(=C([H])C([H])=C1[H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C(Cl)C([H])=C1Cl
[H]N1C([H])=C(N=C1C1=C([H])C(=C([H])C([H])=C1[H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C1=C([H])C(OC([H])([H])[H])=C([H])C([H])=C1F
[H]N1C([H])=C(N=C1C1=C([H])C(=C([H])C([H])=C1[H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C1=C([H])C(OC([H])([H])C([H])([H])[H])=C([H])C([H])=C1F
[H]OC([H])([H])C([H])([H])N([H])C(=O)C([H])([H])C([H])([H])C(=O)C(\[H])=C(/[H])C1=C([H])C2=C([H])C([H])=C([H])C([H])=C2C([H])=C1[H]
[H]N(C(=O)C([H])([H])C([H])([H])C(=O)C(\[H])=C(/[H])C1=C([H])C2=C([H])C([H])=C([H])C([H])=C2C([H])=C1[H])C([H])([H])C(=O)OC([H])([H])C([H])([H])[H]
[H]OC([H])([H])C([H])([H])N([H])C(=O)C([H])([H])C([H])([H])C([H])([H])C(=O)C(\[H])=C(/[H])C1=C([H])C2=C([H])C([H])=C([H])C([H])=C2C([H])=C1[H]
[H]N(C(=O)C([H])([H])C([H])([H])C([H])([H])C(=O)C(\[H])=C(/[H])C1=C([H])C2=C([H])C([H])=C([H])C([H])=C2C([H])=C1[H])C1([H])C([H])([H])C1([H])[H]
[H]OC([H])([H])C([H])([H])N([H])C(=O)C([H])([H])C([H])([H])C(=O)C([H])([H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)C1=NN(C(=C1C([H])([H])[H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])C1=C(F)C([H])=C([H])C([H])=C1[H])C1(C#N)C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]N(C(=O)C1=NN(C(=C1C([H])([H])[H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])C1=C(Br)C([H])=C([H])C([H])=C1[H])C1(C#N)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(C(=O)C1=NN(C(=C1Br)C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])C1=C([H])C(Br)=C([H])C([H])=C1[H])C1(C#N)C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]N(C(=O)C1=NN(C(=C1C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C(Br)=C([H])C([H])=C1[H])C1(C#N)C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]N(C(=O)C1=NN(C(=C1C([H])([H])[H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])C1=C([H])C(Br)=C([H])C([H])=C1[H])C1(C#N)C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]N(C(=O)C1=NN(C(=C1C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C(F)C([H])=C([H])C([H])=C1[H])C1(C#N)C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]N(C(=O)C1=NN(C(=C1C#N)C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])C1=C(I)C([H])=C([H])C([H])=C1[H])C1(C#N)C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]N(C(=O)C1=NN(C(=C1C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C(Br)C([H])=C1[H])C1(C#N)C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]OC1=C([H])C([H])=C(C([H])=C1C1=C([H])C([H])=C(OC([H])([H])[H])C(=C1[H])C([H])([H])C([H])=C([H])[H])C([H])([H])C([H])=C([H])[H]
[H]OC1=C([H])C([H])=C(C([H])=C1C1=C([H])C(=C(OC([H])([H])[H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]OC1=C([H])C([H])=C(C([H])=C1C1=C([H])C([H])=C(O[H])C(=C1[H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]OC1=C([H])C([H])=C(C([H])=C1C1=C([H])C(\C([H])=C(/[H])C([H])([H])[H])=C(OC([H])([H])[H])C([H])=C1[H])C([H])([H])C([H])=C([H])[H]
[H]OC1=C([H])C([H])=C(C([H])=C1C1=C([H])C(\C([H])=C(/[H])C([H])([H])[H])=C(O[H])C([H])=C1[H])C([H])([H])C([H])=C([H])[H]
[H]OC1=C(C([H])=C(C([H])=C1[H])C([H])([H])[C@]([H])(Br)C([H])([H])[H])C1=C([H])C([H])=C(OC([H])([H])[H])C(=C1[H])C([H])([H])C([H])=C([H])[H]
[H]OC1=C(C([H])=C(C([H])=C1[H])C([H])([H])C([H])=C([H])[H])C1=C([H])C([H])=C(OC([H])([H])[H])C(=C1[H])C([H])([H])[C@]([H])(Br)C([H])([H])[H]
[H]OC1=C(C([H])=C(C([H])=C1[H])C([H])([H])[C@]([H])(Br)C([H])([H])[H])C1=C([H])C([H])=C(OC([H])([H])[H])C(=C1[H])C([H])([H])[C@]([H])(Br)C([H])([H])[H]
[H]OC1=C([H])C([H])=C(C([H])=C1C([H])([H])C([H])=C([H])[H])C1=C(O[H])C([H])=C([H])C(=C1[H])C([H])([H])[C@]([H])(Br)C([H])([H])[H]
[H]OC1=C([H])C([H])=C(C([H])=C1C([H])([H])[C@]([H])(Br)C([H])([H])[H])C1=C(O[H])C([H])=C([H])C(=C1[H])C([H])([H])[C@]([H])(Br)C([H])([H])[H]
[H]OC1=C([H])C([H])=C(C([H])=C1C([H])([H])C([H])=C([H])[H])C1=C(OC([H])([H])C([H])([H])[H])C([H])=C([H])C(=C1[H])C([H])([H])C([H])=C([H])[H]
[H]OC1=C(C([H])=C(C([H])=C1[H])C([H])([H])C([H])=C([H])[H])C1=C([H])C([H])=C(OC([H])([H])C([H])([H])[H])C(=C1[H])C([H])([H])C([H])=C([H])[H]
[H]OC1=C([H])C([H])=C(C([H])=C1C([H])([H])C([H])=C([H])[H])C1=C(OC([H])([H])C([H])([H])C([H])([H])[H])C([H])=C([H])C(=C1[H])C([H])([H])C([H])=C([H])[H]
[H]OC1=C(C([H])=C(C([H])=C1[H])C([H])([H])C([H])=C([H])[H])C1=C([H])C([H])=C(OC([H])([H])C([H])([H])C([H])([H])[H])C(=C1[H])C([H])([H])C([H])=C([H])[H]
[H]OC1=C([H])C([H])=C(C([H])=C1C([H])([H])C([H])=C([H])[H])C1=C(OC([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])=C([H])C(=C1[H])C([H])([H])C([H])=C([H])[H]
[H]OC1=C(C([H])=C(C([H])=C1[H])C([H])([H])C([H])=C([H])[H])C1=C([H])C([H])=C(OC([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C(=C1[H])C([H])([H])C([H])=C([H])[H]
[H]C([H])=C([H])C([H])([H])C1=C([H])C(=C(OC([H])([H])C([H])([H])[H])C([H])=C1[H])C1=C([H])C([H])=C(OC([H])([H])C([H])([H])[H])C(=C1[H])C([H])([H])C([H])=C([H])[H]
[H]OC1=C(C([H])=C(C([H])=C1[H])C([H])([H])C([H])=C([H])[H])C1=C(O[H])C([H])=C([H])C(=C1[H])C([H])([H])C([H])=C([H])[H]
[H]OC1=C(C([H])=C(C([H])=C1[H])C([H])([H])C([H])=C([H])[H])C1=C([H])C(=C(O[H])C([H])=C1[H])C([H])([H])C([H])=C([H])[H]
[H]O[C@@]1(C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])N(C(=O)C2=C([H])C([H])=C([H])C3=C2C([H])=NN3[H])[C@@]2([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@@]12[H]
[H]O[C@]1(C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])N(C(=O)C2=C([H])C([H])=C([H])C([H])=C2[H])[C@@]2([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@]12[H]
[H]O[C@]1(C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])N(C(=O)C2=C([H])C([H])=C(Cl)C([H])=C2[H])[C@@]2([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@]12[H]
[H]O[C@]1(C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])N(C(=O)C2=C([H])C([H])=C3C([H])=C([H])C([H])=C([H])C3=N2)[C@@]2([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@]12[H]
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[H]N(C(=O)C1=NN(C(=C1C([H])([H])[H])C1=C([H])C([H])=C(Cl)C([H])=C1[H])C1=C(Cl)C([H])=C(Cl)C([H])=C1[H])C1=C([H])C([H])=[N+]([O-])C([H])=C1[H]
[H]N(C(=O)C1=NN(C(=C1C([H])([H])[H])C1=C([H])C([H])=C(Cl)C([H])=C1[H])C1=C(Cl)C([H])=C(Cl)C([H])=C1[H])C1=C([H])N=C(C([H])=C1[H])C([H])([H])[H]
[H]N([H])S(=O)(=O)N([H])C([H])([H])[C@@]1([H])C([H])([H])C([H])([H])[C@]([H])(C([H])([H])N([H])C(=O)C2=NN(C(=C2C([H])([H])[H])C2=C([H])C([H])=C(Cl)C([H])=C2[H])C2=C(Cl)C([H])=C(Cl)C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N(C(=O)C1=NN(C(=C1C([H])([H])[H])C1=C([H])C([H])=C(Cl)C([H])=C1[H])C1=C(Cl)C([H])=C(Cl)C([H])=C1[H])C1=C([H])[N+](=C(C([H])=C1[H])C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)C1=NN(C(=C1C([H])([H])[H])C1=C([H])C([H])=C(Cl)C([H])=C1[H])C1=C([H])C([H])=C(Cl)C([H])=C1Cl)C1=C([H])C([H])=NC([H])=C1[H]
[H]N(C(=O)C1=NN(C(=C1C([H])([H])[H])C1=C([H])C([H])=C(Cl)C([H])=C1[H])C1=C(Cl)C([H])=C(Cl)C([H])=C1[H])C([H])([H])[C@@]1([H])C([H])([H])C([H])([H])[C@@]([H])(C([H])([H])N([H])S(=O)(=O)C([H])([H])[H])C([H])([H])C1([H])[H]
[H]C1=C([H])C2=C(C3=C(O2)C(C#N)=C(C([H])=C3[H])C(F)(F)F)C(OS(=O)(=O)C([H])([H])C([H])([H])C([H])([H])C(F)(F)F)=C1[H]
[H]C1=C([H])C(OS(=O)(=O)C([H])([H])C([H])([H])C([H])([H])C(F)(F)F)=C([H])C2=C1OC1=C2C([H])=C([H])C(=C1C#N)C(F)(F)F
[H]C1=C([H])C(OS(=O)(=O)C([H])([H])C([H])([H])C([H])([H])C(F)(F)F)=C([H])C2=C1C1=C([H])C([H])=C(C(C#N)=C1O2)C(F)(F)F
[H]C1=C([H])C2=C(OC3=C(C#N)C(=C([H])C([H])=C23)C(F)(F)F)C(OS(=O)(=O)C([H])([H])C([H])([H])C([H])([H])C(F)(F)F)=C1[H]
[H]C1=C([H])C2=C(OC3=C(C#N)C(=C([H])C([H])=C3C2([H])[H])C(F)(F)F)C(OS(=O)(=O)C([H])([H])C([H])([H])C([H])([H])C(F)(F)F)=C1[H]
[H]OC([H])([H])C1=C([H])C2=C(C(OC3=C([H])C(OS(=O)(=O)C([H])([H])C([H])([H])C([H])([H])C(F)(F)F)=C([H])C([H])=C3[H])=C([H])C([H])([H])C2=O)C1([H])[H]
[H]N(\N=C1/C(=O)N(C2=C([H])C(OC([H])([H])[H])=C([H])C([H])=C12)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C(=O)C([H])([H])N(C1=C([H])C([H])=C(C2=NON=C12)[N+]([O-])=O)C([H])([H])[H]
[H]N([H])C(=O)[C@@]([H])(N([H])C(=N/S(=O)(=O)C1=C([H])C([H])=C(Cl)C([H])=C1[H])\N1N=C(C2=C([H])C([H])=C(Cl)C([H])=C2[H])[C@@]([H])(C2=C([H])C([H])=C([H])C([H])=C2[H])C1([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N([H])C(=O)[C@@]([H])(N([H])C(=N/S(=O)(=O)C1=C([H])C([H])=C(Cl)C([H])=C1[H])\N1N=C(C2=C([H])C([H])=C(Cl)C([H])=C2[H])[C@@]([H])(C2=C([H])C([H])=C([H])C([H])=C2[H])C1([H])[H])C1([H])C([H])([H])C([H])([H])C1([H])[H]
[H]O[C@]([H])(C([H])([H])[H])[C@]([H])(N([H])C(=N\S(=O)(=O)C1=C([H])C([H])=C(Cl)C([H])=C1[H])\N1N=C(C2=C([H])C([H])=C(Cl)C([H])=C2[H])[C@@]([H])(C2=C([H])C([H])=C([H])C([H])=C2[H])C1([H])[H])C(=O)N([H])[H]
[H]OC([H])([H])[C@]([H])(N([H])C(=N/S(=O)(=O)C1=C([H])C([H])=C(Cl)C([H])=C1[H])\N1N=C(C2=C([H])C([H])=C(Cl)C([H])=C2[H])[C@@]([H])(C2=C([H])C([H])=C([H])C([H])=C2[H])C1([H])[H])C(=O)N([H])[H]
[H]O[C@]([H])(C(=O)N([H])[H])C([H])([H])C([H])([H])N([H])C(=N/S(=O)(=O)C1=C([H])C([H])=C(Cl)C([H])=C1[H])\N1N=C(C2=C([H])C([H])=C(Cl)C([H])=C2[H])[C@@]([H])(C2=C([H])C([H])=C([H])C([H])=C2[H])C1([H])[H]
[H]N([H])C(=O)C([H])([H])N([H])C(=N/S(=O)(=O)C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])\N1N=C(C2=C([H])C([H])=C(Cl)C([H])=C2[H])[C@@]([H])(C2=C([H])C([H])=C([H])C([H])=C2[H])C1([H])[H]
[H]OC1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)\N=C(/N([H])C([H])([H])C(=O)N([H])[H])N1N=C(C2=C([H])C([H])=C(Cl)C([H])=C2[H])[C@@]([H])(C2=C([H])C([H])=C([H])C([H])=C2[H])C1([H])[H]
[H]N([H])C(=O)[C@@]([H])(N([H])C(=N/S(=O)(=O)C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])\N1N=C(C2=C([H])C([H])=C(Cl)C([H])=C2[H])[C@@]([H])(C2=C([H])C([H])=C([H])C([H])=C2[H])C1([H])[H])C([H])([H])[H]
[H]\C(=C(/C(=O)OC([H])([H])C([H])([H])[H])C(=O)C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])N(C2=C1C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]\C(=C(\C#N)S(=O)(=O)C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])N(C2=C1C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]\C(=C(/C(=O)OC([H])([H])C([H])([H])[H])C(=O)C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])N(C2=C1C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]\C(=C(\C#N)S(=O)(=O)C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])N(C2=C1C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]C1=C([H])C(Cl)=C(Cl)C(=C1[H])C(=O)N1C2=C(C([H])=C(OC([H])([H])C([H])([H])[18F])C([H])=C2[H])C(=C1C([H])([H])[H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]OC1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)\N=C(/N([H])[C@]([H])(C(=O)N([H])[H])C([H])([H])[H])N1N=C(C2=C([H])C([H])=C(Cl)C([H])=C2[H])[C@@]([H])(C2=C([H])C([H])=C([H])C([H])=C2[H])C1([H])[H]
[H]N([H])C(=O)[C@@]([H])(N([H])C(=N/S(=O)(=O)C1=C([H])C(OC([H])([H])[H])=C([H])C([H])=C1[H])\N1N=C(C2=C([H])C([H])=C(Cl)C([H])=C2[H])[C@@]([H])(C2=C([H])C([H])=C([H])C([H])=C2[H])C1([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N([H])C(=O)C([H])([H])N([H])C(=O)C([H])([H])N([H])C(=N/S(=O)(=O)C1=C([H])C([H])=C(Cl)C([H])=C1[H])\N1N=C(C2=C([H])C([H])=C(Cl)C([H])=C2[H])[C@@]([H])(C2=C([H])C([H])=C([H])C([H])=C2[H])C1([H])[H]
[H]N([H])C(=O)C([H])([H])N([H])C(=O)[C@@]([H])(N([H])C(=N/S(=O)(=O)C1=C([H])C([H])=C(Cl)C([H])=C1[H])\N1N=C(C2=C([H])C([H])=C(Cl)C([H])=C2[H])[C@@]([H])(C2=C([H])C([H])=C([H])C([H])=C2[H])C1([H])[H])C([H])([H])[H]
[H]N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=N/S(=O)(=O)C1=C([H])C([H])=C(Cl)C([H])=C1[H])\N1N=C(C2=C([H])C([H])=C(Cl)C([H])=C2[H])[C@@]([H])(C2=C([H])C([H])=C([H])C([H])=C2[H])C1([H])[H])C([H])([H])[H])C([H])([H])[H]
[H]OC([H])([H])[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=N/S(=O)(=O)C1=C([H])C([H])=C(Cl)C([H])=C1[H])\N1N=C(C2=C([H])C([H])=C(Cl)C([H])=C2[H])[C@@]([H])(C2=C([H])C([H])=C([H])C([H])=C2[H])C1([H])[H])C([H])([H])[H])C(=O)N([H])[H]
[H]OC([H])([H])[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=N/S(=O)(=O)C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])\N1N=C(C2=C([H])C([H])=C(Cl)C([H])=C2[H])[C@@]([H])(C2=C([H])C([H])=C([H])C([H])=C2[H])C1([H])[H])C([H])([H])[H])C(=O)N([H])[H]
[H]N([H])C(=O)C([H])([H])N([H])C(=N/S(=O)(=O)C1=C([H])C([H])=C(Cl)C([H])=C1[H])\N1N=C(C2=C([H])C([H])=C(Cl)C([H])=C2[H])[C@@]([H])(C2=C([H])C([H])=C([H])C([H])=C2[H])C1([H])[H]
[H]N([H])C(=O)C([H])([H])C([H])([H])N([H])C(=N/S(=O)(=O)C1=C([H])C([H])=C(Cl)C([H])=C1[H])\N1N=C(C2=C([H])C([H])=C(Cl)C([H])=C2[H])[C@@]([H])(C2=C([H])C([H])=C([H])C([H])=C2[H])C1([H])[H]
[H]N([H])C(=O)[C@@]([H])(C([H])([H])[H])C([H])([H])N([H])C(=N/S(=O)(=O)C1=C([H])C([H])=C(Cl)C([H])=C1[H])\N1N=C(C2=C([H])C([H])=C(Cl)C([H])=C2[H])[C@@]([H])(C2=C([H])C([H])=C([H])C([H])=C2[H])C1([H])[H]
[H]N([H])C(=O)[C@@]([H])(N([H])C(=N/S(=O)(=O)C1=C([H])C([H])=C(Cl)C([H])=C1[H])\N1N=C(C2=C([H])C([H])=C(Cl)C([H])=C2[H])[C@@]([H])(C2=C([H])C([H])=C([H])C([H])=C2[H])C1([H])[H])C([H])([H])[H]
[H]N([H])C(=O)C(N([H])C(=N/S(=O)(=O)C1=C([H])C([H])=C(Cl)C([H])=C1[H])\N1N=C(C2=C([H])C([H])=C(Cl)C([H])=C2[H])[C@@]([H])(C2=C([H])C([H])=C([H])C([H])=C2[H])C1([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]N([H])C(=O)C([H])([H])[C@]([H])(N([H])C(=N/S(=O)(=O)C1=C([H])C([H])=C(Cl)C([H])=C1[H])\N1N=C(C2=C([H])C([H])=C(Cl)C([H])=C2[H])[C@@]([H])(C2=C([H])C([H])=C([H])C([H])=C2[H])C1([H])[H])C(=O)N([H])[H]
[H]N([H])C(=O)[C@@]([H])(N([H])C(=N/S(=O)(=O)C1=C([H])C([H])=C(Cl)C([H])=C1[H])\N1N=C(C2=C([H])C([H])=C(Cl)C([H])=C2[H])[C@@]([H])(C2=C([H])C([H])=C([H])C([H])=C2[H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N([H])C(=O)C([H])([H])N([H])C(=O)[C@@]([H])(N([H])C(=N/S(=O)(=O)C1=C([H])C([H])=C(Cl)C([H])=C1[H])\N1N=C(C2=C([H])C([H])=C(Cl)C([H])=C2[H])[C@@]([H])(C2=C([H])C([H])=C([H])C([H])=C2[H])C1([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N([H])C(=O)C([H])([H])N([H])C(=O)[C@@]([H])(N([H])C(=N/S(=O)(=O)C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])\N1N=C(C2=C([H])C([H])=C(Cl)C([H])=C2[H])[C@@]([H])(C2=C([H])C([H])=C([H])C([H])=C2[H])C1([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=N/S(=O)(=O)C1=C([H])C([H])=C(Cl)C([H])=C1[H])\N1N=C(C2=C([H])C([H])=C(Cl)C([H])=C2[H])[C@@]([H])(C2=C([H])C([H])=C([H])C([H])=C2[H])C1([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H]
[H]OC([H])([H])[C@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=N/S(=O)(=O)C1=C([H])C([H])=C(Cl)C([H])=C1[H])\N1N=C(C2=C([H])C([H])=C(Cl)C([H])=C2[H])[C@@]([H])(C2=C([H])C([H])=C([H])C([H])=C2[H])C1([H])[H])[C@]([H])(O[H])C([H])([H])[H])C(=O)N([H])[H]
[H]N(C(=O)C1=C([H])C2=C([H])C([H])=C(OC([H])([H])[H])C(OC([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])=C2N([H])C1=O)C([H])([H])C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]N(C(=O)C1=C([H])C2=C([H])C([H])=C(OC([H])([H])[H])C(OC([H])([H])[H])=C2N([H])C1=O)C([H])([H])C([H])([H])C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]N(C(=O)C1=C([H])C2=C([H])C([H])=C(OC([H])([H])[H])C(OC([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])=C2N([H])C1=O)C([H])([H])C([H])([H])C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]N(C(=O)C1=C([H])C2=C([H])C([H])=C(OC([H])([H])[H])C(OC([H])([H])[H])=C2N([H])C1=O)C([H])([H])[C@]([H])(F)C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)C1=C([H])C2=C([H])C([H])=C(OC([H])([H])[H])C(OC([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])=C2N([H])C1=O)C([H])([H])[C@]([H])(F)C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)C1=C([H])C2=C([H])C(=C(OC([H])([H])[H])C(OC([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])=C2N([H])C1=O)[N+]([O-])=O)C([H])([H])C([H])([H])C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]N(C(=O)C1=C([H])C2=C([H])C([H])=C(OC([H])([H])[H])C(OC([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])=C2N([H])C1=O)C([H])([H])C([H])([H])F
[H]N(C(=O)C1=C([H])C2=C([H])C([H])=C(OC([H])([H])[H])C(OC([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])=C2N([H])C1=O)C([H])([H])C([H])([H])C([H])([H])F
[H]N(C(=O)C1=C([H])C2=C([H])C([H])=C(OC([H])([H])[H])C(OC([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])=C2N([H])C1=O)C([H])([H])C1=C([H])N(N=N1)C([H])([H])C([H])([H])F
[H]N(C(=O)C1=C([H])C2=C([H])C([H])=C(OC([H])([H])[H])C(OC([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])=C2N([H])C1=O)C([H])([H])C([H])([H])C1=C([H])N(N=N1)C([H])([H])C([H])([H])F
[H]O[C@@]1(C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[C@]([H])(C2=C(OC([H])([H])[H])C([H])=C(C([H])=C2OC([H])([H])[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C1([H])[H]
[H]OC1=C2N([H])C(=O)C(=C([H])C2=C([H])C(=C1OC([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C(=O)OC([H])([H])[H]
[H]N(C(=O)C1=C([H])C2=C([H])C([H])=C(OC([H])([H])[H])C(OC([H])([H])C([H])([H])C([H])([H])[H])=C2N([H])C1=O)C([H])([H])C([H])([H])C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]N(C(=O)C1=C([H])C2=C([H])C([H])=C(OC([H])([H])[H])C(OC([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])=C2N(C1=O)C([H])([H])[H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]N(C(=O)C1=C([H])C2=C([H])C([H])=C(OC([H])([H])[H])C(OC([H])([H])C([H])([H])[H])=C2N([H])C1=O)C([H])([H])C([H])([H])C1=C([H])C([H])=NC([H])=C1[H]
[H]N(C(=O)C1=C([H])C2=C([H])C([H])=C(OC([H])([H])[H])C(OC([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])=C2N([H])C1=O)C([H])([H])C([H])([H])C1=C([H])C([H])=NC([H])=C1[H]
[H]OC1=C2N(C(=O)C(=C([H])C2=C([H])C(=C1OC([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C(=O)N([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C(F)C([H])=C1[H])C([H])([H])[H]
[H]OC1=C2N([H])C(=O)C(=C([H])C2=C([H])C(=C1OC([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C(=O)N([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]OC(=O)C1=C([H])C2=C([H])C([H])=C(OC([H])([H])[H])C(OC([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])=C2N([H])C1=O
[H]OC1=C([H])C(=C([H])C(O[H])=C1C([H])([H])C(\[H])=C(/C([H])([H])[H])C([H])([H])C([H])([H])C([H])=C(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])S(=O)(=O)C1=C([H])C([H])=C2N(C(=NC2=C1[H])C([H])([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H]
[H]C1=C2N(C(=NC2=C([H])C(=C1[H])S(=O)(=O)C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])C([H])([H])C1([H])[H]
[H]C1=C2N(C(=NC2=C([H])C(=C1[H])S(=O)(=O)C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])C([H])([H])C1([H])[H]
[H]C1=C2N(C(=NC2=C([H])C(=C1[H])S(=O)(=O)C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H])C([H])([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])C([H])([H])C1([H])[H]
[H]OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])S(=O)(=O)C1=C([H])C([H])=C2N(C(=NC2=C1[H])C([H])([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])C([H])([H])C1([H])[H]
[H]OC([H])([H])C(C([H])([H])[H])(C([H])([H])[H])S(=O)(=O)C1=C([H])C([H])=C2N(C(=NC2=C1[H])C([H])([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])C([H])([H])C1([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])S(=O)(=O)C1=C([H])C([H])=C2N(C(=NC2=C1[H])C([H])([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])C([H])([H])C1([H])[H]
[H]C1=C2N(C(=NC2=C([H])C(=C1[H])S(=O)(=O)C([H])([H])C([H])([H])[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])C([H])([H])C1([H])[H]
[H]C1=C2N(C(=NC2=C([H])C(=C1[H])S(=O)(=O)C([H])([H])C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])C([H])([H])C1([H])[H]
[H]C1=C2N(C(=NC2=C([H])C(=C1[H])S(=O)(=O)C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C1([H])C([H])([H])C1([H])[H]
[H]C1=C2N(C(=NC2=C([H])C(=C1[H])S(=O)(=O)C([H])([H])C([H])([H])[H])C([H])([H])C1([H])C([H])([H])C1([H])[H])C([H])([H])C1([H])C([H])([H])C1([H])[H]
[H]C1=C2N(C(=NC2=C([H])C(=C1[H])S(=O)(=O)C([H])([H])C([H])([H])[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C1([H])C([H])([H])C1([H])[H]
[H]C1=C2N(C(=NC2=C([H])C(=C1[H])S(=O)(=O)C([H])([H])C([H])([H])[H])C1(C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C1([H])C([H])([H])C1([H])[H]
[H]C1=C2N(C(=NC2=C([H])C(=C1[H])S(=O)(=O)C([H])([H])C([H])([H])[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])[C@@]1([H])OC([H])([H])C([H])([H])C1([H])[H]
[H]C1=C2N(C(=NC2=C([H])C(=C1[H])S(=O)(=O)C([H])([H])C([H])([H])[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C1([H])C([H])([H])C1([H])[H]
[H]C1=C2N(C(=NC2=C([H])C(=C1[H])S(=O)(=O)C([H])([H])C([H])([H])[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])OC(F)(F)F
[H]C1=C2N(C(=NC2=C([H])C(=C1[H])S(=O)(=O)C([H])([H])C([H])([H])[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H]
[H]C1=C2N(C(=NC2=C([H])C(=C1[H])S(=O)(=O)C([H])([H])C([H])([H])[H])C1(C([H])([H])[H])C([H])([H])C1([H])[H])C([H])([H])C1([H])C([H])([H])C1([H])[H]
[H]OC([H])([H])C([H])(OC([H])([H])C([H])([H])C([H])([H])C([H])([H])C(\[H])=C(\[H])C([H])([H])C(\[H])=C(\[H])C([H])([H])C(\[H])=C(\[H])C([H])([H])C(\[H])=C(\[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])O[H]
[H]N(C(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@]1([H])SC([H])([H])[C@]2([H])N([H])C(=O)N([H])[C@]12[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C(=O)OC([H])([H])C([H])([H])C([H])([H])C([H])([H])C(\[H])=C(\[H])C([H])([H])C(\[H])=C(\[H])C([H])([H])C(\[H])=C(\[H])C([H])([H])C(\[H])=C(\[H])C([H])([H])C([H])([H])C([H])([H])C(=O)N([H])C1([H])C([H])([H])C1([H])[H]
[H]OC([H])([H])[C@]([H])(N([H])C(=O)C([H])([H])C([H])([H])C([H])([H])C(\[H])=C(\[H])C([H])([H])C(\[H])=C(\[H])C([H])([H])C(\[H])=C(\[H])C([H])([H])C(\[H])=C(\[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])OC(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@]1([H])SC([H])([H])[C@]2([H])N([H])C(=O)N([H])[C@]12[H])C([H])([H])[H]
[H]N(C(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@]1([H])SC([H])([H])[C@]2([H])N([H])C(=O)N([H])[C@]12[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C(=O)OC([H])([H])[C@]([H])(N([H])C(=O)C([H])([H])C([H])([H])C([H])([H])C(\[H])=C(\[H])C([H])([H])C(\[H])=C(\[H])C([H])([H])C(\[H])=C(\[H])C([H])([H])C(\[H])=C(\[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])[H]
[H]C#CC([H])([H])C([H])([H])C([H])([H])C(=O)OC([H])([H])[C@]([H])(N([H])C(=O)C([H])([H])C([H])([H])C([H])([H])C(\[H])=C(\[H])C([H])([H])C(\[H])=C(\[H])C([H])([H])C(\[H])=C(\[H])C([H])([H])C(\[H])=C(\[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])[H]
[H]C#CC([H])([H])C([H])([H])C([H])([H])C(=O)N([H])[C@]([H])(C(=O)OC([H])([H])[C@]([H])(N([H])C(=O)C([H])([H])C([H])([H])C([H])([H])C(\[H])=C(\[H])C([H])([H])C(\[H])=C(\[H])C([H])([H])C(\[H])=C(\[H])C([H])([H])C(\[H])=C(\[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C(=O)C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC([H])([H])[C@]([H])(OC(=O)C([H])([H])C([H])([H])C([H])([H])C(\[H])=C(\[H])C([H])([H])C(\[H])=C(\[H])C([H])([H])C(\[H])=C(\[H])C([H])([H])C(\[H])=C(\[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])OC(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@]1([H])SC([H])([H])[C@]2([H])N([H])C(=O)N([H])[C@]12[H]
[H]OC([H])([H])[C@@]([H])(OC([H])([H])C([H])([H])C([H])([H])C([H])([H])C(\[H])=C(\[H])C([H])([H])C(\[H])=C(\[H])C([H])([H])C(\[H])=C(\[H])C([H])([H])C(\[H])=C(\[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])OC(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@]1([H])SC([H])([H])[C@]2([H])N([H])C(=O)N([H])[C@]12[H]
[H]OC([H])([H])[C@@]([H])(OC([H])([H])C([H])([H])C([H])([H])C([H])([H])C(\[H])=C(\[H])C([H])([H])C(\[H])=C(\[H])C([H])([H])C(\[H])=C(\[H])C([H])([H])C(\[H])=C(\[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])OC(=O)C([H])([H])C([H])([H])C([H])([H])C#C[H]
[H]N([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1N=C(C([H])=C1C1=C([H])C(=C(Cl)C([H])=C1[H])C([H])([H])[H])C(=O)N([H])[C@@]1([H])[C@@]2(C([H])([H])[H])C([H])([H])C([H])([H])[C@]([H])(C2([H])[H])C1(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)C1=C([H])N(C2=C(C([H])=C([H])C([H])=C2OC([H])([H])[H])C1=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])[C@]12C([H])([H])[C@@]3([H])C([H])([H])[C@]([H])(C([H])([H])[C@]([H])(C3([H])[H])C1([H])[H])C2([H])[H]
[H]N(C(=O)C1=C([H])N(C2=C(C([H])=C([H])C([H])=C2[N+]([O-])=O)C1=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])[C@]12C([H])([H])[C@@]3([H])C([H])([H])[C@]([H])(C([H])([H])[C@]([H])(C3([H])[H])C1([H])[H])C2([H])[H]
[H]N(C(=O)C1=C([H])N(C2=C(C([H])=C(Br)C([H])=C2OC([H])([H])[H])C1=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])[C@]12C([H])([H])[C@@]3([H])C([H])([H])[C@]([H])(C([H])([H])[C@]([H])(C3([H])[H])C1([H])[H])C2([H])[H]
[H]N(C(=O)C1=C([H])N(C2=C(C([H])=C(C([H])=C2OC([H])([H])[H])C2=C([H])C([H])=C([H])C([H])=C2[H])C1=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])[C@]12C([H])([H])[C@@]3([H])C([H])([H])[C@]([H])(C([H])([H])[C@]([H])(C3([H])[H])C1([H])[H])C2([H])[H]
[H]N(C(=O)C1=C([H])N(C2=C(C([H])=C(C([H])=C2OC([H])([H])[H])C2=C([H])C([H])=C([H])O2)C1=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])[C@]12C([H])([H])[C@@]3([H])C([H])([H])[C@]([H])(C([H])([H])[C@]([H])(C3([H])[H])C1([H])[H])C2([H])[H]
[H]N(C(=O)C1=C([H])N2C3=C(C([H])=C([H])C([H])=C3OC([H])([H])[C@@]2([H])C([H])([H])C([H])([H])[H])C1=O)[C@]12C([H])([H])[C@@]3([H])C([H])([H])[C@]([H])(C([H])([H])[C@]([H])(C3([H])[H])C1([H])[H])C2([H])[H]
[H]N(C(=O)C1=C(N([H])C2=C(C([H])=C(Br)C([H])=C2[H])C1=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])[C@]12C([H])([H])[C@@]3([H])C([H])([H])[C@]([H])(C([H])([H])[C@]([H])(C3([H])[H])C1([H])[H])C2([H])[H]
[H]N(C(=O)C1=C(N([H])C2=C(C([H])=C(C([H])=C2[H])C2=C([H])C([H])=C([H])O2)C1=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])[C@]12C([H])([H])[C@@]3([H])C([H])([H])[C@]([H])(C([H])([H])[C@]([H])(C3([H])[H])C1([H])[H])C2([H])[H]
[H]OC1=C(C(=O)N([H])[C@]23C([H])([H])[C@@]4([H])C([H])([H])[C@]([H])(C([H])([H])[C@]([H])(C4([H])[H])C2([H])[H])C3([H])[H])C(=O)N(C2=C1C([H])=C(Br)C([H])=C2[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]OC1=C(C(=O)N([H])[C@]23C([H])([H])[C@@]4([H])C([H])([H])[C@]([H])(C([H])([H])[C@]([H])(C4([H])[H])C2([H])[H])C3([H])[H])C(=O)N(C2=C1C([H])=C(C([H])=C2[H])C1=C([H])C([H])=C([H])O1)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]N(C(=O)C1=C([H])C2=C(C([H])=C([H])C([H])=C2[H])N(C1=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])[C@]12C([H])([H])[C@@]3([H])C([H])([H])[C@]([H])(C([H])([H])[C@]([H])(C3([H])[H])C1([H])[H])C2([H])[H]
[H]N(C(=O)C1=C([H])N([H])C2=C(C([H])=C([H])C([H])=C2OC([H])([H])[H])C1=O)[C@]12C([H])([H])[C@@]3([H])C([H])([H])[C@]([H])(C([H])([H])[C@]([H])(C3([H])[H])C1([H])[H])C2([H])[H]
[H]N(C(=O)C1=C([H])N([H])C2=C(C([H])=C([H])C([H])=C2OC([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C1=O)[C@]12C([H])([H])[C@@]3([H])C([H])([H])[C@]([H])(C([H])([H])[C@]([H])(C3([H])[H])C1([H])[H])C2([H])[H]
[H]N(C(=O)C1=C([H])N([H])C2=C(C([H])=C([H])C([H])=C2C2=C([H])C([H])=C([H])C([H])=C2[H])C1=O)[C@]12C([H])([H])[C@@]3([H])C([H])([H])[C@]([H])(C([H])([H])[C@]([H])(C3([H])[H])C1([H])[H])C2([H])[H]
[H]N(C(=O)N1C([H])([H])C([H])([H])N(C2=C(Cl)C([H])=C(C([H])=N2)C(F)(F)F)C([H])([H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C(Cl)C(Cl)=C1[H]
[H]N(C(=O)N1C([H])([H])C([H])([H])N(C2=C(Cl)C([H])=C(C([H])=N2)C(F)(F)F)C([H])([H])C([H])([H])C1([H])[H])C1=NOC(=C1[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)N1C([H])([H])C([H])([H])N(C2=C(Cl)C([H])=C(C([H])=N2)C(F)(F)F)C([H])([H])C([H])([H])C1([H])[H])C1=C([H])C(=NN1C([H])([H])[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)N1C([H])([H])C([H])([H])N(C2=C(Cl)C([H])=C(C([H])=N2)C(F)(F)F)C([H])([H])C([H])([H])C1([H])[H])C1=NC(=C([H])S1)C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C1=NSC(=N1)N1C([H])([H])C([H])([H])N(C2=C(Cl)C([H])=C(C([H])=N2)C(F)(F)F)C([H])([H])C([H])([H])C1([H])[H]
[H]C1=C([H])C(Cl)=C([H])C2=C1N=C(S2)N1C([H])([H])C([H])([H])N(C2=C(Cl)C([H])=C(C([H])=N2)C(F)(F)F)C([H])([H])C([H])([H])C1([H])[H]
[H]C1=C([H])C(=C([H])C2=C1OC(=N2)N1C([H])([H])C([H])([H])N(C2=C(Cl)C([H])=C(C([H])=N2)C(F)(F)F)C([H])([H])C([H])([H])C1([H])[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)N1C([H])([H])C([H])([H])N(C2=C(Cl)C([H])=C([H])C([H])=N2)C([H])([H])C([H])([H])C1([H])[H])C1=NOC(=C1[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)N1C([H])([H])C([H])([H])N(C2=C([H])C([H])=C(C([H])=N2)C(F)(F)F)C([H])([H])C([H])([H])C1([H])[H])C1=NOC(=C1[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)N1C([H])([H])C([H])([H])N(C2=C([H])C([H])=C(C#N)C([H])=N2)C([H])([H])C([H])([H])C1([H])[H])C1=NOC(=C1[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)N1C([H])([H])C([H])([H])N(C2=C([H])C(C#N)=C([H])C([H])=N2)C([H])([H])C([H])([H])C1([H])[H])C1=NOC(=C1[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])C(=C([H])C2=C1OC(=N2)N1C([H])([H])C([H])([H])N(C(=O)C([H])([H])C2([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C([H])([H])C1([H])[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])C(=C([H])C2=C1OC(=N2)N1C([H])([H])C([H])([H])N(C(=O)C2([H])C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])C([H])([H])C([H])([H])C1([H])[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])C(=C([H])C2=C1OC(=N2)N1C([H])([H])C([H])([H])N(C(=O)N2C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])C([H])([H])C([H])([H])C1([H])[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])C(=C([H])C2=C1OC(=N2)N1C([H])([H])C([H])([H])N(C(=O)N2C([H])([H])C([H])([H])S(=O)(=O)C([H])([H])C2([H])[H])C([H])([H])C([H])([H])C1([H])[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])C(Cl)=C([H])C2=C1N=C(S2)N1C([H])([H])C([H])([H])N(C(=O)C2([H])C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])C([H])([H])C([H])([H])C1([H])[H]
[H]C1=C([H])C(Cl)=C([H])C2=C1SC(=N2)N1C([H])([H])C([H])([H])N(C(=O)C2([H])C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])C([H])([H])C([H])([H])C1([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C1=NSC(=N1)N1C([H])([H])C([H])([H])N(C(=O)C2([H])C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])C([H])([H])C([H])([H])C1([H])[H]
[H]C1([H])OC([H])([H])C([H])([H])C([H])(C(=O)N2C([H])([H])C([H])([H])N(C3=NC(=C(Cl)S3)C(F)(F)F)C([H])([H])C([H])([H])C2([H])[H])C1([H])[H]
[H]C1=C([H])C(=C([H])C([H])=C1F)[C@@]1([H])C([H])([H])[C@@]2([H])N(C([H])([H])[H])[C@]([H])(C([H])([H])C2([H])[H])[C@@]1([H])C(=O)OC([H])([H])[H]
[H]C1=C([H])C(=C([H])C([H])=C1F)[C@]1(OC2=C(O1)C([H])=C(C(=O)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C(F)=C2[H])C1=C(Cl)C([H])=C(Cl)C([H])=C1[H]
[H]C1=C([H])C(OS(=O)(=O)C([H])([H])C([H])([H])C([H])([H])C(F)(F)F)=C([H])C(OC2=C([H])C([H])=C([H])C(=C2C#N)C(F)(F)F)=C1[H]
[H]OC1=C(OC([H])([H])[H])C([H])=C(C([H])=C1[H])C([H])([H])N([H])C(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C(\[H])=C(/[H])C([H])([H])[C@]([H])(OC(=O)C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]OC1=C(OC([H])([H])[H])C([H])=C(C([H])=C1I)C([H])([H])N([H])C(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C(\[H])=C(/[H])C([H])([H])[C@]([H])(OC(=O)C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]OC1=C(OC([H])([H])[H])C([H])=C(C(I)=C1[H])C([H])([H])N([H])C(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C(\[H])=C(/[H])C([H])([H])[C@]([H])(OC(=O)C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]OC1=C(OC([H])([H])[H])C([H])=C(C([H])=C1[H])C([H])([H])N([H])C(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@]1([H])O[C@@]1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]OC1=C(OC([H])([H])[H])C([H])=C(C([H])=C1[H])C([H])([H])N([H])C(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@]([H])(OC(=O)C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]OC1=C(OC([H])([H])[H])C([H])=C(C([H])=C1[H])C([H])([H])N([H])C(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])O[C@]1([H])C([H])([H])C([H])([H])[C@]([H])(OC(=O)C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]OC1=C(OC([H])([H])[H])C([H])=C(C([H])=C1[H])C([H])([H])N([H])C(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C(\[H])=C(/[H])C([H])([H])[C@]([H])(OC(=O)C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]N(C(=O)C1=C([H])C2=C(N([H])C1=O)C(OC([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])=C(OC([H])([H])[H])C([H])=C2[H])C([H])([H])C1=C([H])C2=C(OC([H])([H])O2)C([H])=C1[H]
[H]C1=C([H])C([H])=C(C(Cl)=N1)[C@]([H])(OC1([H])C([H])([H])N(C(=O)N(C([H])([H])[H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C1([H])[H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]C1=C([H])C([H])=C(S1)S(=O)(=O)N(C1=C([H])C([H])=C2N(C(=NC2=C1[H])C([H])([H])C1=NC([H])=C(OC([H])([H])C([H])([H])[H])C([H])=C1[H])C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])[H]
[H]C([H])=C([H])C([H])([H])N1C2=C([H])C([H])=C(C([H])=C2C2=C1C([H])([H])C([H])([H])N(C([H])([H])C1([H])C([H])([H])C1([H])[H])C2([H])[H])C(=O)N1C([H])([H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])C1([H])[H]
[H]C1=C2N(C3=C(C2=C([H])C(=C1[H])C(=O)N1C([H])([H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])C1([H])[H])C([H])([H])N(C([H])([H])C3([H])[H])C1([H])C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])S(=O)(=O)C([H])([H])C([H])([H])[H]
[H]C1=NC([H])=C([H])C(=C1[H])S(=O)(=O)C1=C([H])C2=C(C([H])=C1[H])N(C(=N2)C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])C([H])([H])C([H])([H])N(C(=O)C([H])([H])[H])C([H])([H])C1([H])[H]
[H]C(=O)N1C([H])([H])C([H])([H])C([H])(C([H])([H])N2C3=C(N=C2C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])=C(C([H])=C3[H])S(=O)(=O)C2=NC([H])=C([H])S2)C([H])([H])C1([H])[H]
[H]C1=C([H])N=C(S1)S(=O)(=O)C1=C([H])C2=C(C([H])=C1[H])N(C(=N2)C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])C([H])([H])C([H])([H])N(C(=O)C([H])([H])[H])C([H])([H])C1([H])[H]
[H]C1=C2N(C(=NC2=C([H])C(=C1[H])S(=O)(=O)C([H])([H])C([H])([H])C([H])([H])C(F)(F)F)C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]C1=C([H])C(=C([H])C(OC([H])([H])C([H])([H])[H])=N1)S(=O)(=O)C1=C([H])C([H])=C2N(C(=NC2=C1[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]N(C1=C([H])C(=C([H])C([H])=N1)S(=O)(=O)C1=C([H])C2=C(C([H])=C1[H])N(C(=N2)C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C([H])([H])C([H])([H])C([H])([H])OC([H])([H])[H]
[H]C1=NC(OC([H])([H])C([H])([H])C([H])([H])OC([H])([H])[H])=C([H])C(=C1[H])S(=O)(=O)C1=C([H])C2=C(C([H])=C1[H])N(C(=N2)C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]C1=NC(OC([H])([H])C([H])([H])OC([H])([H])[H])=C([H])C(=C1[H])S(=O)(=O)C1=C([H])C2=C(C([H])=C1[H])N(C(=N2)C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]OC([H])([H])C([H])([H])C([H])([H])OC1=C([H])C(=C([H])C([H])=N1)S(=O)(=O)C1=C([H])C2=C(C([H])=C1[H])N(C(=N2)C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]C1=NC(=C([H])C(=C1[H])S(=O)(=O)C1=C([H])C2=C(C([H])=C1[H])N(C(=N2)C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C([H])([H])C([H])([H])C([H])([H])OC([H])([H])[H]
[H]N(C(=O)C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1=C([H])C(=C([H])C([H])=N1)S(=O)(=O)C1=C([H])C2=C(C([H])=C1[H])N(C(=N2)C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]N1C([H])([H])C([H])([H])C([H])(C([H])([H])N2C3=C(N=C2C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])=C(C([H])=C3[H])S(=O)(=O)C([H])([H])C([H])([H])C([H])([H])C(F)(F)F)C([H])([H])C1([H])[H]
[H]C(=O)N1C([H])([H])C([H])([H])C([H])(C([H])([H])N2C3=C(N=C2C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])=C(C([H])=C3[H])S(=O)(=O)C([H])([H])C([H])([H])C([H])([H])C(F)(F)F)C([H])([H])C1([H])[H]
[H]C1=C([H])C(=C([H])C2=C1N(C(=N2)C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])C([H])([H])C([H])([H])N(C(=O)C([H])([H])[H])C([H])([H])C1([H])[H])S(=O)(=O)C([H])([H])C([H])([H])C([H])([H])C(F)(F)F
[H]C1=C([H])C(=C([H])C2=C1N(C(=N2)C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])C([H])([H])C([H])([H])N(C(=O)C([H])([H])C([H])([H])[H])C([H])([H])C1([H])[H])S(=O)(=O)C([H])([H])C([H])([H])C([H])([H])C(F)(F)F
[H]C1=C([H])C(=C([H])C2=C1N(C(=N2)C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])C([H])([H])C([H])([H])N(C(=O)C(F)(F)F)C([H])([H])C1([H])[H])S(=O)(=O)C([H])([H])C([H])([H])C([H])([H])C(F)(F)F
[H]C1=C([H])C(=C([H])C2=C1N(C(=N2)C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])C([H])([H])C([H])([H])N(C(=O)OC([H])([H])[H])C([H])([H])C1([H])[H])S(=O)(=O)C([H])([H])C([H])([H])C([H])([H])C(F)(F)F
[H]C1=C([H])C(=C([H])C2=C1N(C(=N2)C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])C([H])([H])C([H])([H])N(C(=O)C([H])([H])OC([H])([H])[H])C([H])([H])C1([H])[H])S(=O)(=O)C([H])([H])C([H])([H])C([H])([H])C(F)(F)F
[H]C(=O)N1C([H])([H])C([H])([H])C([H])(C([H])([H])N2C3=C(N=C2C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])=C(C([H])=C3[H])S(=O)(=O)C([H])([H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]C1=C([H])C(=C([H])C2=C1N(C(=N2)C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])C([H])([H])C([H])([H])N(C(=O)C([H])([H])[H])C([H])([H])C1([H])[H])S(=O)(=O)C([H])([H])C([H])([H])[H]
[H]C1=C([H])C(=C([H])C2=C1N(C(=N2)C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])C([H])([H])C([H])([H])S(=O)(=O)C([H])([H])C1([H])[H])S(=O)(=O)C([H])([H])C([H])([H])[H]
[H]C(=O)N1C([H])([H])C([H])([H])C([H])(C([H])([H])N2C3=C(N=C2C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])=C(C([H])=C3[H])S(=O)(=O)C([H])([H])C2([H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H]
[H]C1=C([H])C(=C([H])C2=C1N(C(=N2)C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])C([H])([H])C([H])([H])N(C(=O)C([H])([H])[H])C([H])([H])C1([H])[H])S(=O)(=O)C([H])([H])C1([H])C([H])([H])C1([H])[H]
[H]C1=C([H])C(=C([H])C2=C1N(C(=N2)C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])C([H])([H])C([H])([H])S(=O)(=O)C([H])([H])C1([H])[H])S(=O)(=O)C([H])([H])C1([H])C([H])([H])C1([H])[H]
[H]C1=C([H])C(=C([H])C2=C1N(C(=N2)C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])C([H])([H])C([H])([H])N(C(=O)C([H])([H])[H])C([H])([H])C1([H])[H])S(=O)(=O)C1([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]C1=C([H])C(=C([H])C2=C1N(C(=N2)C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])C([H])([H])C([H])([H])N(C(=O)C([H])([H])[H])C([H])([H])C1([H])[H])S(=O)(=O)C([H])([H])C([H])([H])OC([H])([H])[H]
[H]OC([H])([H])C([H])([H])C([H])([H])S(=O)(=O)C1=C([H])C2=C(C([H])=C1[H])N(C(=N2)C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])C([H])([H])C([H])([H])N(C(=O)C([H])([H])[H])C([H])([H])C1([H])[H]
[H]C1=C([H])C(=C([H])C2=C1N(C(=N2)C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])C([H])([H])C([H])([H])N(C(=O)C([H])([H])[H])C([H])([H])C1([H])[H])S(=O)(=O)C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]N(C(=O)C([H])([H])[H])C([H])([H])C([H])([H])C1=C([H])C(=C([H])C([H])=N1)S(=O)(=O)C1=C([H])C2=C(C([H])=C1[H])N(C(=N2)C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]N(C(=O)C1=NN(C(N2C([H])=C([H])C([H])=C2Cl)=C1C([H])([H])[H])C1=C([H])C([H])=C(Cl)C([H])=C1Cl)C([H])([H])C1=C([H])C(Cl)=C(Cl)C([H])=C1[H]
[H]N(C(=O)C1=NN(C(N2C([H])=C([H])C([H])=C2Cl)=C1C([H])([H])[H])C1=C([H])C([H])=C(Cl)C([H])=C1Cl)C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(C(=O)C1=NN(C(N2C(Cl)=C([H])C([H])=C2Cl)=C1C([H])([H])[H])C1=C([H])C([H])=C(Cl)C([H])=C1Cl)C([H])([H])C1=C([H])C(Cl)=C(Cl)C([H])=C1[H]
[H]N(C(=O)C1=NN(C(N2C(Cl)=C([H])C([H])=C2Cl)=C1C([H])([H])[H])C1=C([H])C([H])=C(Cl)C([H])=C1Cl)C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(C(=O)C1=NN(C(N2C([H])=C3C(=C2[H])C([H])([H])C([H])([H])C([H])([H])C3([H])[H])=C1C([H])([H])[H])C1=C([H])C([H])=C(Cl)C([H])=C1Cl)C([H])([H])C1=C([H])C(Cl)=C(Cl)C([H])=C1[H]
[H]N(C(=O)C1=NN(C(N2C([H])=C3C(=C2[H])C([H])([H])C([H])([H])C([H])([H])C3([H])[H])=C1C([H])([H])[H])C1=C([H])C([H])=C(Cl)C([H])=C1Cl)C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(C(=O)C1=NN(C(N2C([H])=C([H])C([H])=C2[H])=C1C([H])([H])C([H])([H])[H])C1=C([H])C([H])=C(Cl)C([H])=C1Cl)C([H])([H])C1=C([H])C(Cl)=C(Cl)C([H])=C1[H]
[H]N(C(=O)C1=NN(C(N2C([H])=C([H])C([H])=C2[H])=C1C([H])([H])C([H])([H])[H])C1=C([H])C([H])=C(Cl)C([H])=C1Cl)C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(C(=O)C1=NN(C(N2C(=C([H])C([H])=C2C([H])([H])[H])C([H])([H])[H])=C1C([H])([H])C([H])([H])[H])C1=C([H])C([H])=C(Cl)C([H])=C1Cl)C([H])([H])C1=C([H])C(Cl)=C(Cl)C([H])=C1[H]
[H]N(C(=O)C1=NN(C(N2C(=C([H])C([H])=C2C([H])([H])[H])C([H])([H])[H])=C1C([H])([H])C([H])([H])[H])C1=C([H])C([H])=C(Cl)C([H])=C1Cl)C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(C(=O)C1=NN(C(N2C(=C([H])C([H])=C2C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H])=C1C([H])([H])[H])C1=C([H])C([H])=C(Cl)C(Cl)=C1[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(C(=O)C1=NN(C(N2C([H])=C([H])C([H])=C2Cl)=C1C([H])([H])[H])C1=C([H])C([H])=C(Cl)C(Cl)=C1[H])C([H])([H])C1=C([H])C([H])=C(Cl)C(Cl)=C1[H]
[H]N(C(=O)C1=NN(C(N2C([H])=C([H])C([H])=C2Cl)=C1C([H])([H])[H])C1=C([H])C([H])=C(Cl)C(Cl)=C1[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(C(=O)C1=NN(C(N2C(Cl)=C([H])C([H])=C2Cl)=C1C([H])([H])[H])C1=C([H])C([H])=C(Cl)C(Cl)=C1[H])C([H])([H])C1=C([H])C([H])=C(Cl)C(Cl)=C1[H]
[H]N(C(=O)C1=NN(C(N2C(Cl)=C([H])C([H])=C2Cl)=C1C([H])([H])[H])C1=C([H])C([H])=C(Cl)C(Cl)=C1[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(C(=O)C1=NN(C(N2C([H])=C([H])C([H])=C2[H])=C1C([H])([H])C([H])([H])[H])C1=C([H])C([H])=C(Cl)C(Cl)=C1[H])C([H])([H])C1=C([H])C([H])=C(Cl)C(Cl)=C1[H]
[H]N(C(=O)C1=NN(C(N2C([H])=C([H])C([H])=C2[H])=C1C([H])([H])C([H])([H])[H])C1=C([H])C([H])=C(Cl)C(Cl)=C1[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(C(=O)C1=NN(C(N2C(=C([H])C([H])=C2C([H])([H])[H])C([H])([H])[H])=C1C([H])([H])C([H])([H])[H])C1=C([H])C([H])=C(Cl)C(Cl)=C1[H])C([H])([H])C1=C([H])C([H])=C(Cl)C(Cl)=C1[H]
[H]N(C(=O)C1=NN(C(N2C(=C([H])C([H])=C2C([H])([H])[H])C([H])([H])[H])=C1C([H])([H])C([H])([H])[H])C1=C([H])C([H])=C(Cl)C(Cl)=C1[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]OC1=C([H])C(OC([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C(=O)OC([H])(C([H])([H])O[H])C([H])([H])O[H])=C([H])C(=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]OC1=C([H])C(OC([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C(=O)OC([H])(C([H])([H])O[H])C([H])([H])O[H])=C([H])C([H])=C1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]OC1=C([H])C([H])=C(C(OC([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C(=O)OC([H])(C([H])([H])O[H])C([H])([H])O[H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]OC1=C([H])C(OC([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C(=O)OC([H])(C([H])([H])O[H])C([H])([H])O[H])=C([H])C(=C1[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]OC1=C([H])C(OC([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])OC([H])(C([H])([H])O[H])C([H])([H])O[H])=C([H])C(=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]OC1=C([H])C(OC([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])OC([H])(C([H])([H])O[H])C([H])([H])O[H])=C([H])C([H])=C1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]OC1=C([H])C(OC([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])OC([H])(C([H])([H])O[H])C([H])([H])O[H])=C([H])C(=C1[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]OC1=C([H])C(OC([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C(=O)OC([H])([H])[C@]([H])(O[H])C([H])([H])O[H])=C([H])C(=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]OC1=C([H])C([H])=C(C(OC([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C(=O)OC([H])([H])[C@]([H])(O[H])C([H])([H])O[H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]OC1=C([H])C(OC([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C(=O)OC([H])([H])[C@]([H])(O[H])C([H])([H])O[H])=C([H])C(=C1[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]\C(=C(/[H])C([H])([H])C(\[H])=C(\[H])C([H])([H])C([H])([H])C([H])([H])C(=O)N(C1=C(N(N(C1=O)C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])C(\[H])=C(\[H])C([H])([H])C(\[H])=C(\[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]N(C(=O)C([H])([H])C([H])([H])C([H])([H])C(\[H])=C(\[H])C([H])([H])C(\[H])=C(\[H])C([H])([H])C(\[H])=C(\[H])C([H])([H])C(\[H])=C(\[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C1=C(N(N(C1=O)C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H])C([H])([H])[H]
[H]\C(=C(/[H])C([H])([H])C(\[H])=C(\[H])C([H])([H])C([H])([H])C([H])([H])C(=O)OC([H])([H])C([H])([H])C1=C([H])SC([H])=C1[H])C([H])([H])C(\[H])=C(\[H])C([H])([H])C(\[H])=C(\[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
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[H]N(C(=O)C([H])([H])C([H])([H])C([H])([H])C(\[H])=C(\[H])C([H])([H])C(\[H])=C(\[H])C([H])([H])C(\[H])=C(\[H])C([H])([H])C(\[H])=C(\[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C1=C([H])SC([H])=C1[H]
[H]N(C(=O)C([H])([H])C([H])([H])C([H])([H])C(\[H])=C(\[H])C([H])([H])C(\[H])=C(\[H])C([H])([H])C(\[H])=C(\[H])C([H])([H])C(\[H])=C(\[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C1=C([H])SC([H])=C1[H]
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[H]C1=C(N(N(\C1=N\C(=O)C1=C(F)C(=C([H])C([H])=C1[H])C(F)(F)F)C([H])([H])C1([H])C([H])([H])C1([H])[H])C([H])([H])[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]C1=C(N(N(\C1=N\C(=O)C1=C(F)C(=C([H])C([H])=C1[H])C(F)(F)F)C([H])([H])C([H])([H])OC([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]C1=C(N(N(\C1=N\C(=O)C1=C(F)C(=C([H])C([H])=C1[H])C(F)(F)F)C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]C1=C(N(N(\C1=N\C(=O)C1=C(F)C(=C([H])C([H])=C1[H])C(F)(F)F)C([H])([H])C1([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]C1=C(N(N(\C1=N\C(=O)C1=C(C([H])=C([H])C(=C1[H])C(F)(F)F)C([H])([H])[H])C([H])([H])C1([H])C([H])([H])C1([H])[H])C([H])([H])[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]C1=C(N(N(\C1=N\C(=O)C1=C(Cl)C(=C([H])C([H])=C1[H])C(F)(F)F)C([H])([H])C1([H])C([H])([H])C1([H])[H])C([H])([H])[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]C1=C(N(N(\C1=N\C(=O)C1=C([H])C(=C([H])C([H])=C1[H])C(F)(F)F)C([H])([H])C1([H])C([H])([H])C1([H])[H])C([H])([H])[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]C1=C(ON(\C1=N\C(=O)C1=C([H])C(=C([H])C([H])=C1[H])C(F)(F)F)C([H])([H])C1([H])C([H])([H])C1([H])[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
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[H]C1=C([H])C(=C([H])C(=C1[H])C(F)(F)F)C(=O)\N=C1/SC(=NN1C([H])([H])C1([H])C([H])([H])C1([H])[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
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[H]C1=C([H])C(=C([H])C(=C1[H])C(F)(F)F)C(=O)\N=C1/OC(=C(N1C([H])([H])C1([H])C([H])([H])C1([H])[H])C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H]
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[H]N(C(=O)C([H])([H])C([H])([H])C1=NC(=NO1)C1=C(Cl)C([H])=C(F)C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1Cl)C(F)(F)F
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[H]C1=C([H])C(=C([H])C([H])=C1Cl)C1=C(C(=NN1C1=C([H])C([H])=C(Cl)C([H])=C1Cl)C1=NN=NN1C1([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C([H])([H])[H]
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[H]C1=C2N(C(=NC2=C([H])C(=C1[H])S(=O)(=O)C([H])([H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(OC([H])([H])C([H])([H])[H])C([H])=C1[H])C([H])([H])C1([H])C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]C1=C2N(C(=NC2=C([H])C(=C1[H])S(=O)(=O)C([H])([H])C([H])([H])[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]C1=C2N(C(=NC2=C([H])C(=C1[H])S(=O)(=O)C([H])([H])C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]C1=C2N(C(=NC2=C([H])C(=C1[H])S(=O)(=O)C([H])([H])C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]C1=C([H])C(=C([H])C(F)=N1)S(=O)(=O)C1=C([H])C([H])=C2N(C(=NC2=C1[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]C1=C([H])C([H])=C(O1)S(=O)(=O)C1=C([H])C([H])=C2N(C(=NC2=C1[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]C1=NC([H])=C([H])C(=C1[H])S(=O)(=O)C1=C([H])C([H])=C2N(C(=NC2=C1[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]C1=C2N(C(=NC2=C([H])C(=C1[H])S(=O)(=O)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N(C(=O)C([H])([H])[H])C([H])([H])[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]C1=C2N(C(=NC2=C([H])C(=C1[H])S(=O)(=O)C1=C([H])C([H])=C(C#N)C([H])=C1[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]C1=C([H])C(=C([H])C(C#N)=C1[H])S(=O)(=O)C1=C([H])C([H])=C2N(C(=NC2=C1[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]C1=C([H])C(Cl)=C(C(Cl)=C1[H])S(=O)(=O)C1=C([H])C([H])=C2N(C(=NC2=C1[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]C1=C2N(C(=NC2=C([H])C(=C1[H])S(=O)(=O)C(F)(F)C1=C([H])C([H])=C(C#N)C([H])=C1[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]C1=C2N(C(=NC2=C([H])C(=C1[H])S(=O)(=O)C([H])([H])C1=C([H])C([H])=C(C#N)C([H])=C1[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(C(=O)C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])S(=O)(=O)C1=C([H])C([H])=C2N(C(=NC2=C1[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]N([H])C([H])([H])C([H])([H])S(=O)(=O)C1=C([H])C([H])=C2N(C(=NC2=C1[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]OC([H])([H])C([H])([H])S(=O)(=O)C1=C([H])C([H])=C2N(C(=NC2=C1[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]C1=C2N(C(=NC2=C([H])C(=C1[H])S(=O)(=O)C([H])([H])C1([H])C([H])([H])C1([H])[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]O[C@@]1([H])C([H])([H])C([H])([H])C2=C(C([H])=C([H])C([H])=C2[H])[C@@]1([H])N([H])C(=O)N1C(=O)N(C2=C([H])C([H])=C([H])C([H])=C12)C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]N(C(=O)N1C(=O)N(C2=C([H])C([H])=C([H])C([H])=C12)C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C1=C2C([H])=C([H])C([H])=C([H])C2=C([H])C([H])=C1[H]
[H]OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])N1C(=O)N(C(=O)N([H])[C@]([H])(C(=O)N([H])[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C2=C([H])C([H])=C([H])C([H])=C12
[H]OC1(C([H])([H])C([H])([H])N2C(=O)N(C(=O)N([H])[C@]([H])(C(=O)N([H])[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C3=C([H])C([H])=C([H])C([H])=C23)C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]OC1(C([H])([H])N2C(=O)N(C(=O)N([H])[C@]([H])(C(=O)N([H])[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C3=C([H])C([H])=C([H])C([H])=C23)C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]N([H])C(=O)[C@@]([H])(N([H])C(=O)N1C(=O)N(C2=C([H])C([H])=C([H])C([H])=C12)C([H])([H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]N([H])C(=O)[C@@]([H])(N([H])C(=O)N1C(=O)N(C2=C([H])C([H])=C([H])C([H])=C12)C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]C1=C2N(C(=NC2=C([H])C(=C1[H])S(=O)(=O)C([H])([H])C([H])([H])C(F)(F)F)C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]C1=C([H])C(=C([H])C(=N1)C([H])([H])[H])S(=O)(=O)C1=C([H])C([H])=C2N(C(=NC2=C1[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]C1=C([H])N=C(S1)S(=O)(=O)C1=C([H])C([H])=C2N(C(=NC2=C1[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]N([H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)C1=C([H])C([H])=C2N(C(=NC2=C1[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)C1=C([H])C([H])=C2N(C(=NC2=C1[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])S(=O)(=O)C1=C([H])C([H])=C2N(C(=NC2=C1[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]C1=C2N(C(=NC2=C([H])C(=C1[H])S(=O)(=O)C([H])([H])C([H])([H])C#N)C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C1=NN(N=N1)C([H])([H])C(=O)C([H])([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C1=NN(N=N1)C([H])([H])C(=O)OC([H])([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C1=NN(N=N1)C([H])([H])C#N
[H]C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C1=NN(N=N1)C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C1=NN=NN1C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N(\N=C1/C(=O)N(C2=C([H])C(OC([H])([H])[H])=C([H])C([H])=C12)C([H])([H])C([H])([H])OC([H])([H])[H])C(=O)C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(\N=C1/C(=O)N(C2=C([H])C(OC([H])([H])[H])=C([H])C([H])=C12)C([H])([H])C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C(=O)C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(\N=C1/C(=O)N(C2=C([H])C(OC([H])([H])[H])=C([H])C([H])=C12)C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C(=O)C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)C([H])([H])C1=C([H])C([H])=C(Br)C([H])=C1[H])C([H])([H])C([H])([H])C([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)C([H])([H])C1=C([H])C([H])=C(Cl)C([H])=C1[H])C([H])([H])C([H])([H])C([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N([H])C1=C([H])C([H])=C(C([H])=C1[H])[C@@]([H])(C(=O)N([H])C([H])([H])C([H])([H])C([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC1=C([H])C([H])=C(C([H])=C1[H])[C@@]([H])(C(=O)N([H])C([H])([H])C([H])([H])C([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)[C@@]([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])[N+]([O-])=O)C([H])([H])C([H])([H])C([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)[C@@]([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)[C@@]([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC(C(=O)N([H])C([H])([H])C([H])([H])C([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)C(C1=C([H])C([H])=C([H])C([H])=C1[H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(\N=C1/C(=O)N(C2=C([H])C(OC([H])([H])[H])=C([H])C([H])=C12)C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C(=O)C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(\N=C1/C(=O)N(C2=C([H])C(OC([H])([H])[H])=C([H])C([H])=C12)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C(=O)C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(\N=C1/C(=O)N(C2=C([H])C(OC([H])([H])[H])=C([H])C([H])=C12)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C(=O)C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)N(C1=C([H])C2=C(C([H])=C1[H])N(C(=N2)C([H])([H])C1=C([H])C2=C(OC([H])([H])C2([H])[H])C([H])=C1[H])C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])[H]
[H]N(C(=O)C1=C([H])C(=C(Br)C([H])=C1[H])S(=O)(=O)N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)C1=C([H])C(=C(Br)C([H])=C1[H])S(=O)(=O)N(C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)C1=C([H])C(=C(Br)C([H])=C1[H])S(=O)(=O)N(C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)C1=C([H])C(=C(Br)C([H])=C1[H])S(=O)(=O)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C([H])([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
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[H]N(C(=O)OC([H])([H])[H])C([H])([H])C([H])([H])N1C2=C(N=C1C1=C([H])C([H])=C([H])C([H])=C1Cl)C(=NC(=N2)C([H])([H])[H])N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H]
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[H]N(C(=O)C1=C([H])N2C3=C(OC([H])([H])[C@@]2([H])C2=C([H])C([H])=C(C([H])=C2[H])C([H])([H])[H])C([H])=C([H])C([H])=C3C1=O)[C@]12C([H])([H])[C@@]3([H])C([H])([H])[C@]([H])(C([H])([H])[C@]([H])(C3([H])[H])C1([H])[H])C2([H])[H]
[H]N(C(=O)C1=C([H])N2C3=C(OC([H])([H])[C@@]2([H])C2=C([H])C([H])=C(C([H])=C2[H])C([H])([H])[H])C([H])=C([H])C([H])=C3C1=O)C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(C(=O)C1=C([H])N2C3=C(O[C@]([H])(C([H])([H])[H])[C@@]2([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])=C([H])C([H])=C3C1=O)[C@]12C([H])([H])[C@@]3([H])C([H])([H])[C@]([H])(C([H])([H])[C@]([H])(C3([H])[H])C1([H])[H])C2([H])[H]
[H]N(C(=O)C1=C([H])N2C3=C(O[C@@]([H])(C([H])([H])[H])[C@]2([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])=C([H])C([H])=C3C1=O)C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(C(=O)C1=C([H])N2C3=C(OC([H])([H])[C@@]2([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])=C([H])C([H])=C3C1=O)[C@]12C([H])([H])[C@]3([H])C([H])([H])[C@](C([H])([H])[H])(C1([H])[H])C([H])([H])[C@@](C([H])([H])[H])(C3([H])[H])C2([H])[H]
[H]N(C(=O)C1=C([H])N2C3=C(OC([H])([H])[C@@]2([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])=C([H])C([H])=C3C1=O)C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(C(=O)C1=C([H])N2C3=C(OC([H])([H])[C@]2([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])=C([H])C([H])=C3C1=O)C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(C(=O)C1=C([H])N2C3=C(OC([H])([H])[C@]2([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])=C([H])C([H])=C3C1=O)C1([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(C(=O)C1=C([H])N2C3=C(OC([H])([H])[C@@]2([H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])=C([H])C([H])=C3C1=O)[C@]12C([H])([H])[C@@]3([H])C([H])([H])[C@]([H])(C([H])([H])[C@]([H])(C3([H])[H])C1([H])[H])C2([H])[H]
[H]N(C(=O)C1=C([H])N2C3=C(OC([H])([H])[C@]2([H])C([H])([H])C([H])([H])[H])C(=C([H])C([H])=C3C1=O)N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H])[C@]12C([H])([H])[C@@]3([H])C([H])([H])[C@]([H])(C([H])([H])[C@]([H])(C3([H])[H])C1([H])[H])C2([H])[H]
[H]N(C(=O)C1=C([H])N2C3=C(OC([H])([H])[C@]2([H])C([H])([H])C([H])([H])[H])C(=C([H])C([H])=C3C1=O)N1C([H])([H])C([H])([H])C([H])([H])C1([H])[H])[C@]12C([H])([H])[C@@]3([H])C([H])([H])[C@]([H])(C([H])([H])[C@]([H])(C3([H])[H])C1([H])[H])C2([H])[H]
[H]N(C(=O)C1=C([H])N2C3=C(OC([H])([H])[C@]2([H])C([H])([H])C([H])([H])[H])C(OC([H])([H])[H])=C([H])C([H])=C3C1=O)[C@]12C([H])([H])[C@@]3([H])C([H])([H])[C@]([H])(C([H])([H])[C@]([H])(C3([H])[H])C1([H])[H])C2([H])[H]
[H]N(C(=O)C1=C([H])N2C3=C(OC([H])([H])[C@]2([H])C([H])([H])C([H])([H])[H])C(F)=C(F)C([H])=C3C1=O)[C@]12C([H])([H])[C@@]3([H])C([H])([H])[C@]([H])(C([H])([H])[C@]([H])(C3([H])[H])C1([H])[H])C2([H])[H]
[H]N(C(=O)C1=C([H])N2C3=C(OC([H])([H])[C@@]2([H])C([H])([H])C([H])([H])[H])C(F)=C([H])C([H])=C3C1=O)[C@]12C([H])([H])[C@@]3([H])C([H])([H])[C@]([H])(C([H])([H])[C@]([H])(C3([H])[H])C1([H])[H])C2([H])[H]
[H]N(C(=O)C1=C([H])N2C3=C(OC([H])([H])C2(C([H])([H])[H])C([H])([H])[H])C([H])=C([H])C([H])=C3C1=O)[C@]12C([H])([H])[C@@]3([H])C([H])([H])[C@]([H])(C([H])([H])[C@]([H])(C3([H])[H])C1([H])[H])C2([H])[H]
[H]N(C(=O)C1=C([H])N2C3=C(OC([H])([H])[C@]2([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])=C(C([H])=C3C1=O)C([H])([H])[H])[C@]12C([H])([H])[C@@]3([H])C([H])([H])[C@]([H])(C([H])([H])[C@]([H])(C3([H])[H])C1([H])[H])C2([H])[H]
[H]N(C(=O)C([H])([H])C([H])([H])C([H])([H])N(C(=O)C1=C([H])C([H])=C2N(C3=C(C2=C1[H])C([H])([H])[C@@]([H])(C([H])([H])C3([H])[H])C1([H])C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)C([H])([H])N(C(=O)C1=C([H])C([H])=C2N(C3=C(C2=C1[H])C([H])([H])[C@]([H])(C([H])([H])C3([H])[H])C1([H])C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C([H])([H])[H])C([H])([H])[H])C1([H])C([H])([H])C1([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N(C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])OC1=C([H])C([H])=C(C([H])=C1[H])C1=C(C(=O)C2=C([H])C([H])=C(OC([H])([H])C([H])([H])N3C([H])([H])C([H])([H])OC([H])([H])C3([H])[H])C([H])=C2[H])C2=C([H])C([H])=C([H])C([H])=C2O1
[H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N(C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])OC1=C([H])C([H])=C(C([H])=C1[H])C1=C(C(=O)C2=C([H])C([H])=C([H])C(OC([H])([H])C([H])([H])N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H])=C2[H])C2=C([H])C([H])=C([H])C([H])=C2O1
[H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N(C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])OC1=C([H])C([H])=C(C([H])=C1[H])C1=C(C(=O)C2=C([H])C([H])=C(C([H])=C2[H])C([H])([H])N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H])C2=C([H])C([H])=C([H])C([H])=C2O1
[H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N(C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])OC1=C([H])C([H])=C(C([H])=C1[H])C1=C(C(=O)C2=C([H])C([H])=C(OC([H])([H])C([H])([H])N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H])C([H])=C2[H])C2=C([H])C([H])=C([H])C([H])=C2O1
[H]C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C(=O)C1=C(OC2=C([H])C([H])=C([H])C([H])=C12)C1=C([H])C([H])=C(OC([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])=C1[H]
[H]C1=C([H])C(=NC(=C1[H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])[C@]([H])(C([H])([H])[H])C1([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1C(=O)N(C(=O)C1([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])C(=NC(=C1F)C([H])([H])N1C([H])([H])C([H])([H])S(=O)(=O)C([H])([H])C1([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1C(=O)N(C(=O)C1([H])[H])C1([H])C([H])([H])C1([H])[H]
[H]C1=C([H])C(=NC(=C1[H])C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1C(=O)N(C(=O)C1([H])[H])C([H])([H])C([H])([H])[H]
[H]C1=C([H])C(=NC(=C1[H])C([H])([H])N1C([H])([H])C([H])([H])S(=O)(=O)C([H])([H])C1([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1C(=O)N(C(=O)C1([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])C(=NC(=C1[H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])C(F)(F)C1([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1C(=O)N(C(=O)C1([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])C(=NC(=C1F)C([H])([H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1C(=O)N(C(=O)C1([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])C(=NC(=C1F)C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])[C@]([H])(F)C1([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1C(=O)N(C(=O)C1([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])C(=NC(=C1[H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])[C@]([H])(F)C1([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1C(=O)N(C(=O)C1([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])C(=NC(=C1F)C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])[C@]([H])(C([H])([H])[H])C1([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1C(=O)N(C(=O)C1([H])[H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])C(=NC(=C1F)C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1C(=O)N(C(=O)C1([H])[H])C([H])([H])C([H])(F)F
[H]C1=C([H])C(=NC(=C1F)C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1C(=O)N(C(=O)C1([H])[H])C([H])([H])C1([H])C([H])([H])C([H])([H])C1([H])[H]
[H]C1=C([H])C(=NC(=C1F)C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1C(=O)N(C(=O)C1([H])[H])C1([H])C([H])([H])C1([H])[H]
[H]C1=C([H])C(=NC(=C1F)C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1C(=O)N(C(=O)C1([H])[H])C([H])([H])C([H])([H])[H]
[H]C1=C(C(=O)C2=C3C([H])=C([H])C([H])=C([H])C3=C(OC([H])([H])C([H])([H])[H])C([H])=C2[H])C2=C(C([H])=C([H])C([H])=C2[H])N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]C1=C([H])C2=C(C([H])=C1[H])C(C(=O)C1=C3C([H])=C(C([H])=C([H])C3=C([H])C([H])=C1[H])C([H])([H])C([H])([H])[H])=C(N2C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])[H]
[H]C1=C(C(=O)N2C([H])([H])[C@@]([H])(N(C([H])([H])[H])[C@]([H])(C([H])([H])[H])C2([H])[H])C([H])([H])[H])C2=C([H])C([H])=C([H])C(OC([H])([H])[H])=C2N1C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N([H])C(=O)C([H])([H])N(C([H])([H])[H])C([H])([H])C1=NC(=NO1)C1=C([H])N(C2=C(Cl)C([H])=C([H])C([H])=C12)C([H])([H])C1([H])C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]C1=C([H])C(Cl)=C(Cl)C(=C1[H])C1=C([H])C([H])=C(N=C1[H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]C1=C([H])C(Cl)=C(Cl)C(=C1[H])C1=C([H])N=C(N=C1[H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]C1=C([H])C(Cl)=C(Cl)C(=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]C1=C([H])C(Cl)=C(Cl)C(=C1[H])C1=C([H])C([H])=C(N=N1)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]C1=C([H])C(Cl)=C(Cl)C(=C1[H])C1=NC([H])=C(N=C1[H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]C1=C([H])C(Cl)=C(Cl)C(=C1[H])C1=NC([H])=C(C([H])=N1)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]C1=C([H])C(Cl)=C(Cl)C(=C1[H])C1=NN=C(N=C1[H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]C1=C([H])C(Cl)=C(Cl)C(=C1[H])C1=C([H])C([H])=C(N=N1)N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]C1=C([H])C(Cl)=C(Cl)C(=C1[H])C1=C([H])C([H])=C(N=N1)N1C([H])([H])C([H])([H])C(F)(F)C([H])([H])C1([H])[H]
[H]C1=C([H])C(Cl)=C(Cl)C(=C1[H])C1=C([H])C([H])=C(N=N1)N1C([H])([H])C([H])([H])S(=O)(=O)C([H])([H])C1([H])[H]
[H]C1=C([H])C(Cl)=C(Cl)C(=C1[H])C1=C([H])C([H])=C(N=N1)N1C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]C1=C([H])C(Cl)=C(Cl)C(=C1[H])C1=C([H])C([H])=C(N=N1)N1[C@@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])[C@@]1([H])C([H])([H])[H]
[H]C1=C([H])[C@]([H])(N(C2=C([H])C([H])=C(N=N2)C2=C([H])C([H])=C([H])C(Cl)=C2Cl)[C@@]1([H])C([H])([H])[H])C([H])([H])[H]
[H]N(C1=C([H])C([H])=C(N=N1)C1=C([H])C([H])=C([H])C(Cl)=C1Cl)C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]C1=C([H])C([H])=C(C(Cl)=C1[H])C1=C([H])C([H])=C(N=N1)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]C1=C([H])C([H])=C(C(=C1[H])C1=C([H])C([H])=C(N=N1)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C([H])([H])[H]
[H]C1=C([H])C([H])=C(C(=C1[H])C1=C([H])C([H])=C(N=N1)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C(F)(F)F
[H]C1=C([H])C([H])=C(C(OC(F)(F)F)=C1[H])C1=C([H])C([H])=C(N=N1)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]C1=C([H])C(=C([H])C(=C1[H])C1=C([H])C([H])=C(N=N1)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C(F)(F)F
[H]C1=C([H])C(=C(C(=C1[H])C1=C([H])C([H])=C(N=N1)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])C(=C(C(=C1[H])C1=C([H])C([H])=C(N=N1)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C(F)(F)F)C(F)(F)F
[H]C1=C(Cl)C([H])=C(C(Cl)=C1[H])C1=C([H])C([H])=C(N=N1)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]C1=C(N=NC(=C1[H])C1=C([H])C(Cl)=C([H])C(Cl)=C1Cl)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])OC1=C([H])C([H])=C([H])C([H])=C1C1=C([H])C([H])=C(N=N1)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]N1C([H])=C(C2=C1C([H])=C([H])C([H])=C2[H])C1=C([H])C([H])=C(N=N1)N1[C@@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])[C@@]1([H])C([H])([H])[H]
[H]C1=C(OC2=C1C([H])=C([H])C([H])=C2[H])C1=C([H])C([H])=C(N=N1)N1[C@@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])[C@@]1([H])C([H])([H])[H]
[H]C1=C([H])C([H])=C2C(=N1)C([H])=C([H])C([H])=C2C1=C([H])C([H])=C(N=N1)N1[C@@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])[C@@]1([H])C([H])([H])[H]
[H]C1=C([H])C([H])=C2C([H])=C([H])C([H])=C(C3=C([H])C([H])=C(N=N3)N3[C@@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])[C@@]3([H])C([H])([H])[H])C2=N1
[H]C1=C([H])C([H])=C2C(C([H])=NC([H])=C2C2=C([H])C([H])=C(N=N2)N2[C@@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])[C@@]2([H])C([H])([H])[H])=C1[H]
[H]C1=NC([H])=C2C([H])=C([H])C([H])=C(C3=C([H])C([H])=C(N=N3)N3[C@@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])[C@@]3([H])C([H])([H])[H])C2=C1[H]
[H]C1=C(C(=O)N2C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])[H])C([H])([H])C2([H])[H])C2=C([H])C([H])=C([H])C3=C2N1[C@@]([H])(C([H])([H])O3)C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]C1=C(C(=O)N2C([H])([H])C([H])([H])N(C([H])([H])[H])[C@@]([H])(C([H])([H])[H])C2([H])[H])C2=C([H])C([H])=C([H])C3=C2N1[C@@]([H])(C([H])([H])O3)C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]C1=C([H])C(OC([H])([H])[H])=C(C([H])=C1[H])C(=O)C1=NC2=C([H])C([H])=C([H])C([H])=C2C([H])=C1[H]
[H]C1=C([H])C([H])=C2C([H])=C([H])C(=NC2=C1[H])C(=O)C1=C([H])C(OC([H])([H])[H])=C([H])C([H])=C1[H]
[H]C1=C([H])C(C(=O)C2=NC3=C([H])C([H])=C([H])C([H])=C3C([H])=C2[H])=C(C([H])=C1[H])C(F)(F)F
[H]C1=C([H])C([H])=C2C([H])=C([H])C(=NC2=C1[H])C(=O)C1=C([H])C(=C([H])C([H])=C1[H])C(F)(F)F
[H]C1=C([H])C([H])=C(C([H])=C1[H])C(=O)C1=NC2=C([H])C([H])=C([H])C([H])=C2C([H])=C1[H]
[H]C1=C([H])C2=C([H])C([H])=C([H])C([H])=C2C(=N1)C(=O)C1=C([H])C([H])=C(C([H])=C1[H])N(C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])C2=C([H])C([H])=C([H])C([H])=C2C(=N1)C(=O)C1=C(C([H])=C([H])C([H])=C1[H])N(C([H])([H])[H])C([H])([H])[H]
[H]C1=NC(C(=O)C2=C([H])C([H])=C([H])C(=C2[H])C(F)(F)F)=C2C([H])=C([H])C([H])=C([H])C2=C1[H]
[H]C1=C([H])C2=C([H])C([H])=C([H])C([H])=C2C(=N1)C(=O)C1=C(C([H])=C([H])C([H])=C1[H])C(F)(F)F
[H]C1=C([H])C2=C([H])C([H])=C([H])C([H])=C2C(=N1)C(=O)C1=C([H])C([H])=C(C([H])=C1[H])C(F)(F)F
[H]C1=C([H])C([H])=C2C([H])=C([H])C(=NC2=C1[H])C(=O)C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]C1=C([H])C(N(C([H])([H])[H])C([H])([H])[H])=C(C([H])=C1[H])C(=O)C1=NC2=C([H])C([H])=C([H])C([H])=C2C([H])=C1[H]
[H]C1=C([H])C([H])=C2C([H])=C([H])C(=NC2=C1[H])C(=O)C1=C([H])C([H])=C(C([H])=C1[H])N(C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])C2=C(C([H])=C1[H])C(C(=O)C1=C3C([H])=C([H])C([H])=C([H])C3=C(C([H])=C1[H])C([H])([H])C([H])([H])[H])=C(N2C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])[H]
[H]C1=C(C(=O)C2=C3C([H])=C([H])C([H])=C([H])C3=C(C([H])=C2[H])C([H])([H])C([H])([H])[H])C2=C(C([H])=C([H])C([H])=C2[H])N1C([H])([H])C([H])([H])C([H])([H])[H]
[H]C1=C(C(=O)C2=C3C([H])=C(C([H])=C([H])C3=C([H])C([H])=C2[H])C([H])([H])C([H])([H])[H])C2=C(C([H])=C([H])C([H])=C2[H])N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]C1=C(C(=O)C2=C3C([H])=C([H])C([H])=C([H])C3=C(C([H])=C2[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C2=C(C([H])=C([H])C([H])=C2[H])N1C([H])([H])C([H])([H])C([H])([H])[H]
[H]C1=C(C(=O)C2=C3C([H])=C([H])C([H])=C([H])C3=C(C([H])=C2[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C2=C(C([H])=C([H])C([H])=C2[H])N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]C1=C([H])C2=C(C([H])=C1[H])C(C(=O)C1=C3C([H])=C([H])C([H])=C([H])C3=C(C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])=C(N2C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])C2=C(C([H])=C1[H])C(C(=O)C1=C3C([H])=C([H])C([H])=C([H])C3=C(C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])=C(N2C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])[H]
[H]C1=C(C(=O)C2=C3C([H])=C([H])C([H])=C([H])C3=C(OC([H])([H])C([H])([H])[H])C([H])=C2[H])C2=C(C([H])=C([H])C([H])=C2[H])N1C([H])([H])C([H])([H])C([H])([H])[H]
[H]C1=C([H])C2=C(C([H])=C1[H])C(C(=O)C1=C3C([H])=C([H])C([H])=C([H])C3=C(OC([H])([H])C([H])([H])[H])C([H])=C1[H])=C(N2C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])C2=C(C([H])=C1[H])C(C(=O)C1=C3C([H])=C([H])C([H])=C([H])C3=C(OC([H])([H])C([H])([H])[H])C([H])=C1[H])=C(N2C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])C2=C(C([H])=C1[H])C(C(=O)C1=C3C([H])=C([H])C(OC([H])([H])[H])=C([H])C3=C([H])C([H])=C1[H])=C(N2C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])C2=C(C([H])=C1[H])C(C(=O)C1=C3C([H])=C(OC([H])([H])[H])C([H])=C([H])C3=C([H])C([H])=C1[H])=C(N2C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])C2=C(C([H])=C1[H])C(C(=O)C1=C3C([H])=C(OC([H])([H])[H])C([H])=C([H])C3=C([H])C([H])=C1[H])=C(N2C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])[H]
[H]C1=C(C(=O)C2=C3C([H])=C([H])C(OC([H])([H])[H])=C([H])C3=C([H])C([H])=C2[H])C2=C(C([H])=C([H])C([H])=C2[H])N1C([H])([H])C([H])([H])C([H])([H])[H]
[H]C1=C(C(=O)C2=C3C([H])=C(OC([H])([H])[H])C([H])=C([H])C3=C([H])C([H])=C2[H])C2=C(C([H])=C([H])C([H])=C2[H])N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]C1=C(C(=O)C2=C3C([H])=C(OC([H])([H])[H])C([H])=C([H])C3=C([H])C([H])=C2[H])C2=C(C([H])=C([H])C([H])=C2[H])N1C([H])([H])C([H])([H])C([H])([H])[H]
[H]C1=C(C(=O)C2=C3C([H])=C([H])C(OC([H])([H])[H])=C([H])C3=C([H])C([H])=C2[H])C2=C(C([H])=C([H])C([H])=C2[H])N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]C1=C(C(=O)C2=C3C([H])=C([H])C([H])=C([H])C3=C(C([H])=C2[H])C([H])([H])C([H])([H])C([H])([H])[H])C2=C(C([H])=C([H])C([H])=C2[H])N1C([H])([H])C([H])([H])C([H])([H])[H]
[H]C1=C([H])C2=C(N=C([H])C([H])=C2O1)C1=C([H])C([H])=C(N=C1[H])N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N([H])C1=C(N=C(C([H])=C1[H])C([H])([H])[H])C1=C([H])C([H])=C(N=C1[H])N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N([H])C1=C(N=C([H])C([H])=C1[H])C1=C([H])C([H])=C(N=C1[H])N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]C1=NC(=C([H])C([H])=C1C1=C(C([H])=C(C([H])=N1)C([H])([H])[H])C([H])([H])[H])N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]C1=NC(C2=C([H])C([H])=C(N=C2[H])N2C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])=C(C([H])=C1[H])C([H])([H])[H]
[H]C1=NC(=C(C#N)C([H])=C1[H])C1=C([H])C([H])=C(N=C1[H])N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]C1=NC(=C(Cl)C([H])=C1[H])C1=C([H])C([H])=C(N=C1[H])N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]C1=NC(=C(Cl)C([H])=C1Cl)C1=C([H])C([H])=C(N=C1[H])N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]C1=NC(=C([H])C([H])=C1Cl)C1=C([H])C([H])=C(N=C1[H])N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]C1=C([H])C(Cl)=C(Cl)C(=C1[H])C1=C([H])C(C(=O)N2C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])=C(N=C1[H])N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]C1=C([H])C(Cl)=C(Cl)C(=C1[H])C1=C([H])C(C(=O)N(C([H])([H])[H])C([H])([H])[H])=C(N=C1[H])N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]OC(=O)C1=C(N=C([H])C(=C1[H])C1=C([H])C([H])=C([H])C(Cl)=C1Cl)N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]C1=C([H])C(Cl)=C(Cl)C(=C1[H])C1=C(C([H])=C(N=C1[H])N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C(F)(F)F
[H]C1=C([H])C(Cl)=C(Cl)C(=C1[H])C1=C([H])C(=C(N=C1[H])N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C(F)(F)F
[H]C1=C([H])C(Cl)=C(Cl)C(=C1[H])C1=C(C#N)C([H])=C(N=C1[H])N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]C1=C([H])C(Cl)=C(Cl)C(=C1[H])C1=C([H])C(C#N)=C(N=C1[H])N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]C1=C([H])C(F)=C(F)C(=C1[H])C1=C([H])C([H])=C(N=C1[H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]C1=NC(=C([H])C([H])=C1C1=C([H])C(Cl)=C([H])C([H])=C1Cl)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]C1=C([H])C(Cl)=C(C(=C1[H])C1=C([H])C([H])=C(N=C1[H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C([H])([H])[H]
[H]C1=C([H])C([H])=C(C(Cl)=C1[H])C1=C([H])C([H])=C(N=C1[H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]C1=C([H])C(Cl)=C([H])C(=C1[H])C1=C([H])C([H])=C(N=C1[H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]C1=NC(=C([H])C([H])=C1C1=C([H])C([H])=C(Cl)C(Cl)=C1[H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]N(C1=C([H])C([H])=C(C([H])=N1)C1=C([H])C([H])=C([H])C(Cl)=C1Cl)C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]C1=NC(=C([H])C([H])=C1C1=C([H])C([H])=C([H])C(Cl)=C1Cl)N1[C@@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])[C@@]1([H])C([H])([H])[H]
[H]C1=C([H])C(Cl)=C(Cl)C(=C1[H])C1=C([H])C([H])=C(N=C1[H])N1C(=O)C([H])([H])C([H])([H])C1=O
[H]C1=C([H])C(Cl)=C(Cl)C(=C1[H])C1=C([H])C([H])=C(N=C1[H])N1C(=O)C([H])([H])C([H])([H])C1([H])[H]
[H]C1=C([H])C(Cl)=C(Cl)C(=C1[H])C1=C([H])C([H])=C(N=C1[H])N1C([H])([H])C([H])([H])SC([H])([H])C1([H])[H]
[H]C1=C([H])C(Cl)=C(Cl)C(=C1[H])C1=C([H])C([H])=C(N=C1[H])N1C([H])([H])C([H])([H])OC([H])([H])C([H])([H])C1([H])[H]
[H]C1=NC(=C([H])C([H])=C1C1=C([H])C([H])=C([H])C(Cl)=C1Cl)N1C([H])([H])[C@]([H])(C([H])([H])[H])C([H])([H])[C@]([H])(C([H])([H])[H])C1([H])[H]
[H]C1=NC(=C([H])C([H])=C1C1=C([H])C([H])=C([H])C(Cl)=C1Cl)N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]C1=C(C(=O)C2=C3C([H])=C([H])C([H])=C([H])C3=C(C([H])=C2[H])C([H])([H])C([H])([H])C([H])([H])[H])C2=C(C([H])=C([H])C([H])=C2[H])N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]C1=C([H])C2=C(C([H])=C1[H])C(C(=O)C1=C3C([H])=C([H])C([H])=C([H])C3=C(C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])[H])=C(N2C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])[H]
[H]C1=C(C(=O)C2=C3C([H])=C([H])C([H])=C([H])C3=C([H])C([H])=C2OC([H])([H])[H])C2=C(C([H])=C([H])C([H])=C2[H])N1C([H])([H])C([H])([H])C([H])([H])[H]
[H]C1=C(C(=O)C2=C3C([H])=C([H])C([H])=C([H])C3=C([H])C([H])=C2OC([H])([H])[H])C2=C(C([H])=C([H])C([H])=C2[H])N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]C1=C(C(=O)C2=C3C([H])=C([H])C([H])=C([H])C3=C([H])C([H])=C2[H])C2=C(C([H])=C([H])C([H])=C2[H])N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]C1=C([H])C2=C(C([H])=C1[H])C(C(=O)C1=C3C([H])=C(C([H])=C([H])C3=C([H])C([H])=C1[H])C([H])([H])[H])=C(N2C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])C2=C(C([H])=C1[H])C(C(=O)C1=C3C([H])=C(C([H])=C([H])C3=C([H])C([H])=C1[H])C([H])([H])[H])=C(N2C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])[H]
[H]C1=C(C(=O)C2=C3C([H])=C([H])C([H])=C([H])C3=C([H])C([H])=C2[H])C2=C(C([H])=C([H])C([H])=C2[H])N1C([H])([H])C([H])([H])C([H])([H])[H]
[H]C1=C(C(=O)C2=C3C([H])=C([H])C([H])=C([H])C3=C(OC([H])([H])[H])C([H])=C2[H])C2=C(C([H])=C([H])C([H])=C2[H])N1C([H])([H])C([H])([H])C([H])([H])[H]
[H]C1=C(C(=O)C2=C3C([H])=C([H])C([H])=C([H])C3=C(OC([H])([H])[H])C([H])=C2[H])C2=C(C([H])=C([H])C([H])=C2[H])N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]C1=C([H])C2=C(C([H])=C1[H])C(C(=O)C1=C3C([H])=C([H])C([H])=C([H])C3=C(OC([H])([H])[H])C([H])=C1[H])=C(N2C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])C2=C(C([H])=C1[H])C(C(=O)C1=C3C([H])=C([H])C([H])=C([H])C3=C(OC([H])([H])[H])C([H])=C1[H])=C(N2C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])[H]
[H]C1=C(C(=O)C2=C3C([H])=C([H])C([H])=C([H])C3=C(C([H])=C2[H])C([H])([H])[H])C2=C(C([H])=C([H])C([H])=C2[H])N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]N(C1(C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])N(C(=O)C2=NN(C(=C2C([H])([H])[H])C2=C([H])C([H])=C(Cl)C([H])=C2[H])C2=C([H])C([H])=C(Cl)C([H])=C2Cl)C([H])([H])C1([H])[H])S(=O)(=O)C([H])([H])[H]
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[H]N([H])C(=O)C1(N([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])N(C(=O)C2=NN(C(=C2C([H])([H])[H])C2=C([H])C([H])=C(Cl)C([H])=C2[H])C2=C([H])C([H])=C(Cl)C([H])=C2Cl)C([H])([H])C1([H])[H]
[H]N(C(=O)OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C1(C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])N(C(=O)C2=NN(C(=C2C([H])([H])[H])C2=C([H])C([H])=C(Cl)C([H])=C2[H])C2=C([H])C([H])=C(Cl)C([H])=C2Cl)C([H])([H])C1([H])[H]
[H]N([H])C1(C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])N(C(=O)C2=NN(C(=C2C([H])([H])[H])C2=C([H])C([H])=C(Cl)C([H])=C2[H])C2=C([H])C([H])=C(Cl)C([H])=C2Cl)C([H])([H])C1([H])[H]
[H]N(C(=O)C([H])([H])[H])C1(C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])N(C(=O)C2=NN(C(=C2C([H])([H])[H])C2=C([H])C([H])=C(Cl)C([H])=C2[H])C2=C([H])C([H])=C(Cl)C([H])=C2Cl)C([H])([H])C1([H])[H]
[H]N(C(=O)N([H])C1(C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])N(C(=O)C2=NN(C(=C2C([H])([H])[H])C2=C([H])C([H])=C(Cl)C([H])=C2[H])C2=C([H])C([H])=C(Cl)C([H])=C2Cl)C([H])([H])C1([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)N([H])C1(C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])N(C(=O)C2=NN(C(=C2C([H])([H])[H])C2=C([H])C([H])=C(Cl)C([H])=C2[H])C2=C([H])C([H])=C(Cl)C([H])=C2Cl)C([H])([H])C1([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]N(C(=O)C1=NN(C(=C1C([H])([H])[H])C1=C([H])C([H])=C(Cl)C([H])=C1[H])C1=C([H])C([H])=C(Cl)C([H])=C1Cl)C1([H])C([H])([H])C([H])([H])N(C(=O)OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N(C(=O)C1=NN(C(=C1C([H])([H])[H])C1=C([H])C([H])=C(Cl)C([H])=C1[H])C1=C([H])C([H])=C(Cl)C([H])=C1Cl)C1([H])C([H])([H])C([H])([H])N(C(=O)C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N(C(=O)C1=NN(C(=C1C([H])([H])[H])C1=C([H])C([H])=C(Cl)C([H])=C1[H])C1=C([H])C([H])=C(Cl)C([H])=C1Cl)C1([H])C([H])([H])C([H])([H])N(C(=O)N([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N(C(=O)N1C([H])([H])C([H])([H])C([H])(N([H])C(=O)C2=NN(C(=C2C([H])([H])[H])C2=C([H])C([H])=C(Cl)C([H])=C2[H])C2=C([H])C([H])=C(Cl)C([H])=C2Cl)C([H])([H])C1([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]N(C(=O)C1=NN(C(=C1C([H])([H])[H])C1=C([H])C([H])=C(Cl)C([H])=C1[H])C1=C([H])C([H])=C(Cl)C([H])=C1Cl)[C@]1([H])C([H])([H])N(C(=O)C([H])([H])[H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(C(=O)C1=NN(C(=C1C([H])([H])[H])C1=C([H])C([H])=C(Cl)C([H])=C1[H])C1=C([H])C([H])=C(Cl)C([H])=C1Cl)[C@]1([H])C([H])([H])N(C([H])([H])C([H])([H])C1([H])[H])S(=O)(=O)C([H])([H])[H]
[H]N(C(=O)C1=C([H])C2=C(N(C1=O)C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C(C(=O)N1C([H])([H])C([H])([H])C([H])(C(=O)N([H])S(=O)(=O)C([H])([H])[H])C([H])([H])C1([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)C1=C([H])C2=C(N(C1=O)C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C(C(=O)OC([H])([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]OC(=O)C(N([H])C(=O)C1=C([H])C2=C(N(C1=O)C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]OC([H])([H])C([H])([H])N(C(=O)C(N([H])C(=O)C1=C([H])C2=C(N(C1=O)C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H]
[H]OC([H])([H])C([H])([H])C([H])([H])N([H])C(=O)C(N([H])C(=O)C1=C([H])C2=C(N(C1=O)C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]OC([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=O)C(N([H])C(=O)C1=C([H])C2=C(N(C1=O)C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]OC([H])([H])C([H])([H])OC([H])([H])C([H])([H])N([H])C(=O)C(N([H])C(=O)C1=C([H])C2=C(N(C1=O)C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)C(N([H])C(=O)C1=C([H])C2=C(N(C1=O)C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)C([H])([H])[H])C([H])([H])C([H])([H])N([H])C(=O)C(N([H])C(=O)C1=C([H])C2=C(N(C1=O)C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]OC(=O)C([H])([H])N([H])C(=O)C(N([H])C(=O)C1=C([H])C2=C(N(C1=O)C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]N([H])C(=O)C([H])([H])N([H])C(=O)C(N([H])C(=O)C1=C([H])C2=C(N(C1=O)C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]OC1([H])C([H])([H])C([H])([H])N(C(=O)C(N([H])C(=O)C2=C([H])C3=C(N(C2=O)C([H])([H])C2([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C3([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]OC(=O)C1([H])C([H])([H])C([H])([H])N(C(=O)C(N([H])C(=O)C2=C([H])C3=C(N(C2=O)C([H])([H])C2([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C3([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N([H])C(=O)C1([H])C([H])([H])C([H])([H])N(C(=O)C(N([H])C(=O)C2=C([H])C3=C(N(C2=O)C([H])([H])C2([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C3([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N(C(=O)C1=C([H])C2=C(N(C1=O)C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C(C(=O)N1C([H])([H])C([H])([H])C([H])(N([H])S(=O)(=O)C([H])([H])[H])C([H])([H])C1([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]N([H])N([H])C(=O)C(N([H])C(=O)C1=C([H])C2=C(N(C1=O)C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]N(N([H])S(=O)(=O)C([H])([H])[H])C(=O)C(N([H])C(=O)C1=C([H])C2=C(N(C1=O)C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)N1C([H])([H])C([H])([H])C([H])([H])[C@]([H])(N([H])C(=O)C2=NN(C(=C2C([H])([H])[H])C2=C([H])C([H])=C(Cl)C([H])=C2[H])C2=C([H])C([H])=C(Cl)C([H])=C2Cl)C1([H])[H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]N(C(=O)C1=NN(C(=C1C([H])([H])[H])C1=C([H])C([H])=C(Cl)C([H])=C1[H])C1=C([H])C([H])=C(Cl)C([H])=C1Cl)[C@]1([H])C([H])([H])N(C(=O)OC([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C1([H])[H]
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[H]N(C(=O)OC([H])([H])[C@]([H])(OC(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C(\[H])=C(\[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])OC([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]O[C@@]([H])(C([H])([H])OC([H])([H])[H])C([H])([H])N([H])C(=O)ON=C1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
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[H]N(C(=O)C([H])([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[C@]([H])(OC(=O)C([H])([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])OC([H])([H])[H]
CCCCCCCCNC(=O)OCC(OC)O[Si](C1=CC=CC=C1)(C1=CC=CC=C1)C(C)(C)C
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[H]OC(=O)C1=C([H])SC(=N1)N([H])C(=O)C1=C([H])C2=C(N(C1=O)C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H]
[H]OC1=C2C([H])=C(C(=O)OC2=C([H])C(=C1[H])C1(C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C1=C(O[H])C([H])=C([H])C([H])=C1[H]
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[H]N(C(=O)C1=C([H])N(C(=C([H])C1=O)C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])[C@@]1([H])[C@@]2([H])C([H])([H])[C@]3([H])C([H])([H])[C@]([H])(C2([H])[H])C([H])([H])[C@@]1([H])C3([H])[H]
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[H]OC1=NC2=C(OC([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C(OC([H])([H])[H])=C([H])C([H])=C2C([H])=C1N([H])C(=O)C([H])([H])C1=C([H])C([H])=C2OC([H])([H])OC2=C1[H]
[H]OC1=NC2=C(OC([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C(OC([H])([H])[H])=C([H])C([H])=C2C([H])=C1C(=O)N([H])C([H])([H])C([H])([H])C1=C([H])C(O[H])=C(O[H])C([H])=C1[H]
[H]OC1=NC2=C(OC([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C(OC([H])([H])[H])=C([H])C([H])=C2C([H])=C1C(=O)N([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])N([H])C(=O)C1=C([H])C2=C([H])C([H])=C(OC([H])([H])[H])C(OC([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])=C2N=C1O[H]
[H]OC1=NC2=C(OC([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C(OC([H])([H])[H])=C([H])C([H])=C2C([H])=C1C(=O)N([H])C([H])([H])C1=C([H])C([H])=C(O[H])C(O[H])=C1[H]
[H]OC1=NC2=C(OC([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C(OC([H])([H])[H])=C([H])C([H])=C2C([H])=C1C(=O)N([H])C1=C(N([H])[H])C([H])=C([H])C([H])=C1[H]
[H]OC1=NC2=C(OC([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C(OC([H])([H])[H])=C([H])C([H])=C2C([H])=C1C(=O)N([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C(N([H])[H])C([H])=C1[H]