[H]OS(=O)(=O)C([H])([H])C([H])([H])N1C(=S)S\C(=C(\[H])C2=C([H])N(N=C2C2=C([H])C([H])=C(C([H])=C2[H])S(=O)(=O)N2C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C2=C([H])C([H])=C([H])C([H])=C2[H])C1=O [H]OS(=O)(=O)C([H])([H])C([H])([H])N1C(=S)S\C(=C(\[H])C2=C([H])N(N=C2C2=C([H])C([H])=C(OC([H])([H])C3=C([H])C([H])=C(Cl)C([H])=C3[H])C([H])=C2[H])C2=C([H])C([H])=C([H])C([H])=C2[H])C1=O [H]OS(=O)(=O)C([H])([H])C([H])([H])N1C(=S)S\C(=C(\[H])C2=C([H])N(N=C2C2=C([H])C([H])=C(OC([H])([H])C3=C(F)C([H])=C([H])C([H])=C3[H])C([H])=C2[H])C2=C([H])C([H])=C([H])C([H])=C2[H])C1=O [H]OS(=O)(=O)C([H])([H])C([H])([H])N1C(=S)S\C(=C(\[H])C2=C([H])N(N=C2C2=C([H])C([H])=C(OC([H])([H])C3=C(Cl)C([H])=C([H])C([H])=C3[H])C([H])=C2[H])C2=C([H])C([H])=C([H])C([H])=C2[H])C1=O [H]OS(=O)(=O)C([H])([H])C([H])([H])N1C(=S)S\C(=C(\[H])C2=C([H])N(N=C2C2=C([H])C([H])=C(OC([H])([H])C3=C([H])C([H])=C([H])C([H])=C3[H])C([H])=C2[H])C2=C([H])C([H])=C([H])C([H])=C2[H])C1=O [H]N1OC(=N\C1=C1\C([H])=C2C([H])=C(OC([H])([H])[H])C([H])=C([H])C2=NC1=O)C1=C([H])C([H])=C(F)C([H])=C1[H] [H]C([H])(OP(=O)(N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C(F)(F)C([H])(F)F [H]OC(=O)[C@@]1([H])N([H])C2=C(C([H])=C([H])C([H])=C2O[H])[C@@]2([H])C([H])=C([H])C([H])([H])[C@@]12[H] [H]OC(=O)C([H])([H])[C@]1([H])N(C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])S(=O)(=O)C2=C1C([H])=C(C([H])=C2[H])C(F)(F)F [H]N(C(=O)C([H])([H])OC1=C([H])C([H])=C([H])C([H])=C1[H])[C@]1([H])C(=O)N2[C@]1([H])SC(C([H])([H])[H])(C([H])([H])[H])[C@]2([H])C(=O)OC([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H] [H]O\C(N([H])[H])=C1/C(=O)[C@@]([H])(N(C([H])([H])[H])C([H])([H])[H])[C@]2([H])C([H])([H])[C@@]3([H])C(=C(O[H])C4=C(C([H])=C([H])C([H])=C4O[H])[C@]3(O[H])C([H])([H])[H])C(=O)[C@]2(O[H])C1=O [H]N1C(=O)N(C2=C(N(C(S[C@]([H])(C(=O)OC([H])([H])C([H])([H])[H])C([H])([H])[H])=N2)C([H])([H])C(\[H])=C(/Cl)C([H])([H])[H])C1=O)C([H])([H])[H] [H]OC(=O)[C@@]([H])(SC1=NC2=C(C3=C(S2)C([H])([H])C([H])([H])C3([H])[H])C(=O)N1C([H])([H])C([H])([H])[H])C([H])([H])[H] [H]OC(=O)C([H])([H])SC1=NC2=C(C3=C(S2)C([H])([H])C([H])([H])C3([H])[H])C(=O)N1C([H])([H])C([H])([H])[H] [H]N(C(=O)C1=C2C(=NC3=C([H])C([H])=C([H])C([H])=C13)C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C1=C([H])C([H])=C([H])O1 [H]OC(=O)C([H])([H])C([H])([H])C1=C(C2=C([H])C3=C(OC([H])=C3C3=C([H])C([H])=C(Cl)C([H])=C3[H])C([H])=C2OC1=O)C([H])([H])[H] [H]OC(=O)[C@@]1([H])N([H])C2=C(C([H])=C(C([H])=C2[H])C([H])([H])[H])[C@@]2([H])C([H])=C([H])C([H])([H])[C@@]12[H] [H]OC(=O)[C@@]1([H])N([H])C2=C(C([H])=C([H])C(=C2C([H])([H])[H])C([H])([H])[H])[C@@]2([H])C([H])=C([H])C([H])([H])[C@@]12[H] [H]C1=C([H])C([H])=C2C(=O)C3=C(C([H])=C([H])C4=C3SN(C4=O)C3=C([H])C([H])=C(Cl)C([H])=C3[H])C(=O)C2=C1[H] [H]N(C(=O)C([H])([H])N1[C@@]2([H])C([H])([H])C([H])([H])C([H])([H])[C@]1([H])C([H])([H])[C@@]([H])(N([H])C(=O)C1=C([H])C(OC([H])([H])[H])=C([H])C([H])=C1[H])C2([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H] [H]C1=C([H])C([H])=C(O1)C1=NC(C2=C([H])C([H])=C([H])O2)=C(N=C1C1=C([H])C([H])=C([H])O1)C1=C([H])C([H])=C([H])O1 [H]N([H])C1=C(C(=O)C([H])([H])OC(=O)C2=C([H])C(=NC3=C([H])C([H])=C([H])C([H])=C23)C2=C([H])C([H])=C([H])O2)C(=O)N(C(=O)N1C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H] [H]\C(=C1\SC2=NC(=NN2C1=O)C1=C([H])C([H])=C([H])O1)C1=C(OC([H])([H])[H])C([H])=C([H])C(Br)=C1[H] [H]N(C(=O)N([H])C1=C(F)C([H])=C(F)C([H])=C1[H])C1=NC(SC([H])([H])C([H])([H])C([H])([H])[H])=NS1 [H]O\N=C(/[H])C1=C([H])C([H])=C([H])N1C1=C([H])C([H])=C([H])C(=C1[H])C(=O)O[H] [H]N(C1=NN2C(S1)=NC1=C([H])C([H])=C([H])C([H])=C1C2=O)C1=C([H])C([H])=C([H])C(=C1[H])C([H])([H])[H] [H]N(C(=O)C1=NOC2=C1C([H])([H])C([H])([H])C2([H])[H])C1=C([H])C([H])=C([H])C([H])=C1C(=O)OC([H])([H])[H] [H]N(C1=C([H])C2=C(C([H])=C1[H])N(C([H])=N2)C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])[H] [H]OC1=C(C([H])=C(Cl)C([H])=C1[H])C([H])([H])N([H])C1=NC2=C([H])C([H])=C([H])C([H])=C2N1C([H])([H])C([H])=C([H])[H] [H]OC(=O)[C@@]([H])(O[H])C1=C([H])C([H])=C([H])O1 [H]N(N([H])C(=O)N([H])[C@]12C([H])([H])[C@@]3([H])C([H])([H])[C@]([H])(C([H])([H])[C@]([H])(C3([H])[H])C1([H])[H])C2([H])[H])C(\[H])=C1/C([H])=C([H])C([H])=C([H])C1=O [H]C1=C([H])C([H])=C(O1)C([H])([H])N1C2=NC3=C([H])C([H])=C([H])C([H])=C3N=C2C2=C1N=C(N(C2=O)C([H])([H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])C([H])([H])[H] [H]C1=C(C([H])=C(Br)C(=O)O1)C(=O)N1C([H])([H])C([H])([H])C([H])([H])C(C([H])([H])[H])(C([H])([H])[H])C1([H])[H] [H]N1OC(=N\C1=C1\C([H])=C2C([H])=C(OC([H])([H])[H])C([H])=C([H])C2=NC1=O)C1=C([H])C([H])=C([H])C([H])=C1[H] [H]OC([H])([H])C([H])([H])N(C1=NC(SC([H])([H])[H])=NC2=C1SC1=C2C2=C(C(=N1)C1=C([H])C([H])=C([H])O1)C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C([H])([H])O[H] [H]C1=C([H])C([H])=C(C2=NO[C@]3([H])C(=O)N(C(=O)[C@]23[H])C2=C(OC([H])([H])[H])C([H])=C([H])C(OC([H])([H])[H])=C2[H])C(Cl)=C1[H] [H]N([H])C(=O)C1=C(SC2=C1C([H])([H])C([H])([H])C2([H])[H])N([H])C(=O)C([H])([H])SC1=NN=C([H])N1C([H])([H])[H] [H]C1=C(SC2=C1C([H])([H])C([H])([H])C2([H])[H])C(=O)OC([H])([H])C(=O)N(C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])[C@]1([H])C([H])([H])C([H])([H])S(=O)(=O)C1([H])[H] [H]N(C(=O)C([H])([H])OC1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])[H])C1=C([H])C(=O)\C(C([H])=C1[H])=C1/OC2=C([H])C([H])=C([H])C([H])=C2N1[H] [H]N(C(=O)C([H])([H])C([H])([H])SC([H])([H])C([H])([H])C(=O)N([H])C([H])([H])C1=C([H])C([H])=C([H])O1)C([H])([H])C1=C([H])C([H])=C([H])O1 [H]N1C2=C(C3=C([H])C([H])=C([H])C([H])=C3C([H])=C2[H])C2=C(C(=O)C([H])([H])C([H])([H])C2([H])[H])[C@]1([H])C1=C([H])C([H])=C([H])O1 [H]OC(=O)C1=C([H])C([H])=C([H])C([H])=C1C1=C([H])C([H])=C(O1)C(\[H])=C1/SC2=NC3=C(N=C([H])C(Br)=C3[H])N2C1=O [H]O[C@@]1([H])C(=O)N([H])C2=C([H])C([H])=C([H])C([H])=C2S[C@@]1([H])C1=C([H])C([H])=C([H])C([H])=C1[H] [H]OC(=O)[C@@]1([H])N([H])C2=C(C([H])=C(C([H])=C2[H])C(=O)OC2([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])[C@@]2([H])C([H])=C([H])C([H])([H])[C@@]12[H] [H]N([H])C(=S)N([H])N([H])C(\[H])=C1/C(=O)C(OC2=C1C1=C(C([H])=C([H])C(=O)O1)C([H])=C2[H])(C([H])([H])[H])C([H])([H])[H] [H]N(C(=O)C1=C([H])C([H])=C(O1)C1=C(Cl)C([H])=C(Cl)C([H])=C1[H])C1=C(C([H])=C([H])C(=C1[H])C1=NN2C(S1)=NN=C2C([H])([H])[H])C([H])([H])[H] [H]OC(=O)C1=C([H])C(=C([H])C([H])=C1[H])N1C(=C([H])C([H])=C1C([H])([H])[H])C([H])([H])[H] [H]C1=C([H])C([H])=C(O1)C1=C(N=C(SC([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])N=N1)C1=C([H])C([H])=C([H])O1 [H]OC(=O)[C@@]1([H])N([H])C2=C(C([H])=C(C([H])=C2[H])C(=O)OC([H])([H])C([H])([H])[H])[C@@]2([H])C([H])=C([H])C([H])([H])[C@@]12[H] [H]OC1=C([H])C2=C(OC(=O)C([H])=C2C([H])([H])N([H])C2=C([H])C([H])=C([H])C([H])=C2F)C([H])=C1C([H])([H])[H] [H]OC(=O)C1=C([H])C(=C(C([H])=C1[H])N1C(=C([H])C([H])=C1C([H])([H])[H])C([H])([H])[H])C([H])([H])[H] [H]OC(=O)C([H])([H])C([H])([H])C([H])([H])N1C(=S)S\C(=C(\[H])C2=C([H])C([H])=C(O2)C2=NC3=C([H])C([H])=C([H])C([H])=C3S2)C1=O [H]OC(=O)C([H])([H])SC1=C([H])C(=C([H])N2C(=O)C3=C(SC(C(=O)OC([H])([H])C([H])([H])[H])=C3C([H])([H])[H])N=C12)C(=O)C1=C([H])C([H])=C([H])C([H])=C1O[H] [H]N([H])C1=C(C([H])=C(S1)C([H])([H])[H])C(=O)C1=C([H])C([H])=C([H])S1 [H]OC(=O)C([H])([H])OC1=C(OC([H])([H])C([H])([H])[H])C([H])=C(\C([H])=N\N([H])C(=O)C2=C([H])C([H])=C(C([H])=C2[H])C2=C([H])SC(=N2)N([H])C2=C([H])C([H])=C(C([H])=C2[H])C([H])([H])[H])C([H])=C1[H] [H]OC(=O)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])OC1=C(Br)C([H])=C(\C([H])=C(\C#N)C2=C([H])C(F)=C([H])C([H])=C2[H])C([H])=C1[H] [H]OC(=O)C([H])([H])OC1=C([H])C([H])=C(\C([H])=N\N([H])C(=O)C2=C([H])C([H])=C(C([H])=C2[H])C2=C([H])SC(=N2)N([H])C2=C([H])C([H])=C(Cl)C([H])=C2[H])C([H])=C1[H] [H]OC(=O)C1=C([H])C(=C([H])C([H])=C1[H])N1C([H])=C([H])C([H])=C1\C([H])=C1\N([H])C(=O)N(C1=O)C1=C([H])C([H])=C(Cl)C([H])=C1[H] [H]OC(=O)C1=C([H])C([H])=C(N([H])C(=O)C([H])([H])C([H])([H])N2C(=S)S\C(=C(\[H])C3=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C([H])=C3[H])C2=O)C([H])=C1[H] [H]OC(=O)C1=C([H])C(N([H])C(=O)C(\C#N)=C(/[H])C2=C([H])C([H])=C(OC([H])([H])C3=C([H])C([H])=C(Cl)C([H])=C3[H])C([H])=C2[H])=C([H])C([H])=C1[H] [H]OC1=C([H])C([H])=C(N([H])C2=NC3=C([H])C([H])=C([H])C([H])=C3C(=N2)N([H])C([H])([H])[C@@]2([H])OC([H])([H])C([H])([H])C2([H])[H])C([H])=C1[H] [H]N(C(=O)N1C([H])([H])C([H])([H])C([H])(C(=O)OC([H])([H])C([H])([H])[H])C([H])([H])C1([H])[H])C1=C([H])C2=C(N=C(C3=C([H])C([H])=C([H])O3)C(=N2)C2=C([H])C([H])=C([H])O2)C([H])=C1[H] [H]C1=C([H])C([H])=C(C([H])=C1[H])N1N(C(=C(N2C(=O)C3=C([H])C([H])=C4C5=C(C([H])=C([H])C(C2=O)=C35)C([H])([H])C4([H])[H])C1=O)C([H])([H])[H])C([H])([H])[H] [H]\C(C1=C([H])C([H])=C([H])O1)=C1\SC2=NC3=C(N=C([H])C(Br)=C3[H])N2C1=O [H]\C(C1=C([H])C([H])=C(O1)C1=C([H])C([H])=C([H])C([H])=C1[N+]([O-])=O)=C1\SC2=NC3=C(N=C([H])C(Br)=C3[H])N2C1=O [H]OC(=O)C1=C([H])C([H])=C([H])C([H])=C1C1=C([H])C([H])=C(O1)C(\[H])=C1/SC2=NC3=C(C([H])=C(C([H])=C3N2C1=O)C([H])([H])[H])C([H])([H])[H] [H]OC(=O)C1=C([H])C([H])=C([H])C([H])=C1C1=C([H])C([H])=C(O1)C(\[H])=C1/SC2=NC3=C(C([H])=C([H])C(=C3C([H])([H])[H])C([H])([H])[H])N2C1=O [H]OC(=O)C1=C([H])C([H])=C([H])C([H])=C1C1=C([H])C([H])=C(O1)C(\[H])=C1\SC2=NC3=C(C([H])=C(C(=C3[H])C([H])([H])[H])C([H])([H])[H])N2C1=O [H]OC(=O)[C@@]1([H])N([H])C2=C(C([H])=C(C([H])=C2[H])C(=O)OC2=C([H])C3=C([H])C([H])=C([H])C([H])=C3C([H])=C2[H])[C@@]2([H])C([H])=C([H])C([H])([H])[C@@]12[H] [H]OC(=O)[C@@]1([H])N([H])C2=C(C([H])=C(C([H])=C2[H])C(=O)OC([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])[C@@]2([H])C([H])=C([H])C([H])([H])[C@@]12[H] [H]\C(C1=C([H])C([H])=C(O1)C1=C([H])C(Cl)=C([H])C(Cl)=C1[H])=C1\SC2=NC3=C(N=C([H])C(Br)=C3[H])N2C1=O [H]OC(=O)[C@@]1([H])N([H])C2=C(C([H])=C(OC(=O)C3=C(Cl)C([H])=C(Cl)C([H])=C3[H])C([H])=C2[H])[C@@]2([H])C([H])=C([H])C([H])([H])[C@@]12[H] [H]OC(=O)[C@@]1([H])N([H])C2=C(C([H])=C(C([H])=C2[H])C(=O)OC2=C([H])C([H])=C([H])C([H])=C2C(=O)OC([H])([H])[H])[C@@]2([H])C([H])=C([H])C([H])([H])[C@@]12[H] [H]C1=C([H])C([H])=C(O1)C1=C(N=C(S[C@]2([H])C(=O)C3=C([H])C([H])=C([H])C([H])=C3C2([H])[H])N=N1)C1=C([H])C([H])=C([H])O1 [H]OC(=O)[C@@]1([H])N([H])C2=C(C([H])=C(Br)C([H])=C2[H])[C@@]2([H])C([H])=C([H])C([H])([H])[C@@]12[H] [H]OC(=O)C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C(O1)C(\[H])=C1/SC2=NC3=C([H])C([H])=C([H])C([H])=C3N2C1=O [H]OC(=O)C1=C([H])C2=C(N([H])[C@]([H])(C(=O)O[H])[C@]3([H])C([H])([H])C([H])=C([H])[C@]23[H])C([H])=C1[H] [H]OC(=O)[C@@]1([H])N([H])C2=C(C(=C(Cl)C([H])=C2O[H])[N+]([O-])=O)[C@@]2([H])C([H])=C([H])C([H])([H])[C@@]12[H] [H]C1=C([H])C([H])=C(O1)C1=C(N=C(SC([H])([H])[H])N=N1)C1=C([H])C([H])=C([H])O1 [H]N(\N=C1/C([H])=C(C2=C(N=C([H])C([H])=C2[H])C1=O)S([O-])(=O)=O)C1=C([H])C2=C(C([H])=C1[H])C([H])=C(C([H])=C2[H])S([O-])(=O)=O [H]N(C(=O)N([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C1=C([H])C2=C(N=C(C3=C([H])C([H])=C([H])O3)C(=N2)C2=C([H])C([H])=C([H])O2)C([H])=C1[H] [H]N(C(=O)N([H])C([H])([H])C([H])([H])C([H])([H])[H])C1=C([H])C2=C(N=C(C3=C([H])C([H])=C([H])O3)C(=N2)C2=C([H])C([H])=C([H])O2)C([H])=C1[H] [H]N(C(=O)N([H])C([H])([H])C([H])([H])C(=O)OC([H])([H])C([H])([H])[H])C1=C([H])C2=C(N=C(C3=C([H])C([H])=C([H])O3)C(=N2)C2=C([H])C([H])=C([H])O2)C([H])=C1[H] [H]OC([H])([H])C([H])([H])C([H])([H])N([H])C(=O)N([H])C1=C([H])C2=C(N=C(C3=C([H])C([H])=C([H])O3)C(=N2)C2=C([H])C([H])=C([H])O2)C([H])=C1[H] [H]N(C(=O)C1=C([H])C2=C(N=C(C3=C([H])C([H])=C([H])O3)C(=N2)C2=C([H])C([H])=C([H])O2)C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=N1 [H]N(C(=S)N([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C(Cl)C([H])=C([H])C([H])=C1Cl [H]C1=C(C(=S)N2C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C2=C([H])C([H])=C([H])C([H])=C2N1C([H])([H])C([H])([H])OC1=C([H])C([H])=C([H])C([H])=C1[H] [H]OC(=O)C1=C([H])C([H])=C(N([H])C(=S)N([H])C(=O)C2=C([H])C([H])=C(O2)C2=C([H])C([H])=C(Br)C([H])=C2[H])C([H])=C1[H] [H]N([H])C1=C(SC(=S)N1C1=C([H])C([H])=C([H])C([H])=C1[H])C(=O)N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H] [H]N([H])C1=C(SC(=S)N1C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H])C(=O)N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H] [H]N([H])S(=O)(=O)C1=C([H])C([H])=C(N([H])C(=S)N2C([H])([H])C([H])([H])N(C([H])([H])C3=C([H])C4=C(OC([H])([H])O4)C([H])=C3[H])C([H])([H])C2([H])[H])C([H])=C1[H] [H]N([H])S(=O)(=O)C1=C([H])C([H])=C(N([H])C(=S)N([H])C2([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])=C1[H] [H]OC(=O)C([H])([H])OC1=C(OC([H])([H])[H])C([H])=C(\C([H])=C2/SC(=O)N(C2=O)C([H])([H])C(=O)N([H])C2=C([H])C([H])=C(C([H])=C2[H])C([H])([H])[H])C([H])=C1Cl [H]OC(=O)C([H])([H])OC1=C([H])C([H])=C(\C([H])=C2/SC3=NC(=C(C(=O)OC([H])([H])C([H])([H])[H])[C@]([H])(N3C2=O)C2=C([H])C([H])=C(SC([H])([H])[H])C([H])=C2[H])C([H])([H])[H])C([H])=C1[H] [H]OC(=O)C([H])([H])OC1=C([H])C([H])=C(\C([H])=C2/SC3=NC(=C(C(=O)OC([H])([H])C([H])([H])[H])[C@]([H])(N3C2=O)C2=C([H])C([H])=C(Cl)C([H])=C2[H])C([H])([H])[H])C([H])=C1[H] [H]N(C(=O)C1=C([H])C2=C(N=C(C3=C([H])C([H])=C([H])O3)C(=N2)C2=C([H])C([H])=C([H])O2)C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H] [H]N(C(=O)C1=C([H])C2=C(N=C(C3=C([H])C([H])=C([H])O3)C(=N2)C2=C([H])C([H])=C([H])O2)C([H])=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H] [H]N(C(=O)C1=C([H])C2=C(N=C(C3=C([H])C([H])=C([H])O3)C(=N2)C2=C([H])C([H])=C([H])O2)C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C(=O)C([H])([H])[H] [H]C1=C([H])C([H])=C(O1)C1=NC2=C(N=C1C1=C([H])C([H])=C([H])O1)C([H])=C(OC([H])([H])[H])C([H])=C2[H] [H]N(C(=O)C1=C([H])C2=C(N=C(C3=C([H])C([H])=C([H])O3)C(=N2)C2=C([H])C([H])=C([H])O2)C([H])=C1[H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H] [H]N(C(=O)C1=C([H])C2=C(N=C(C3=C([H])C([H])=C([H])O3)C(=N2)C2=C([H])C([H])=C([H])O2)C([H])=C1[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H] [H]N(C(=O)N1C([H])([H])C([H])([H])SC([H])([H])C1([H])[H])C1=C([H])C2=C(N=C(C3=C([H])C([H])=C([H])O3)C(=N2)C2=C([H])C([H])=C([H])O2)C([H])=C1[H] [H]N(C(=O)N1C([H])([H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])C1([H])[H])C1=C([H])C2=C(N=C(C3=C([H])C([H])=C([H])O3)C(=N2)C2=C([H])C([H])=C([H])O2)C([H])=C1[H] [H]N(C(=O)N([H])C([H])([H])C([H])([H])C1=C([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C1=C([H])C2=C(N=C(C3=C([H])C([H])=C([H])O3)C(=N2)C2=C([H])C([H])=C([H])O2)C([H])=C1[H] [H]N(C(=O)N1C([H])([H])C([H])([H])[C@@]([H])(C2=C([H])C([H])=C([H])C([H])=C2[H])C1([H])[H])C1=C([H])C2=C(N=C(C3=C([H])C([H])=C([H])O3)C(=N2)C2=C([H])C([H])=C([H])O2)C([H])=C1[H] [H]N(C(=O)N([H])C1=C([H])C2=C(N=C(C3=C([H])C([H])=C([H])O3)C(=N2)C2=C([H])C([H])=C([H])O2)C([H])=C1[H])C1=C([H])C(OC([H])([H])[H])=C([H])C([H])=C1[H] [H]S\C(N([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])=C1/C([H])=C([H])C(=O)C(OC([H])([H])[H])=C1[H] [H]N(C(=O)N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C1=C([H])C2=C(N=C(C3=C([H])C([H])=C([H])O3)C(=N2)C2=C([H])C([H])=C([H])O2)C([H])=C1[H] [H]OC(=O)C([H])([H])OC1=C(OC([H])([H])[H])C([H])=C(\C([H])=C2\SC3=NC(=C(C(=O)OC([H])([H])C([H])([H])[H])[C@]([H])(N3C2=O)C2=C([H])C([H])=C([H])C([H])=C2Cl)C([H])([H])[H])C([H])=C1Cl [H]OC(=O)C([H])([H])OC1=C(OC([H])([H])[H])C([H])=C(\C([H])=C2/SC(=O)N(C2=O)C([H])([H])C(=O)N([H])C2=C([H])C([H])=C([H])C(=C2[H])C([H])([H])[H])C([H])=C1Cl [H]OC(=O)C1=C([H])C([H])=C(\C([H])=C2/SC(=O)N(C2=O)C([H])([H])C(=O)N([H])C2=C([H])C([H])=C(C([H])=C2[H])C([H])([H])[H])C([H])=C1[H] [H]OC(=O)C([H])([H])OC1=C(OC([H])([H])[H])C([H])=C(\C([H])=C2\SC(=NC2=O)N([H])C2=C([H])C(Br)=C([H])C([H])=C2[H])C([H])=C1[H] [H]OC(=O)C([H])([H])OC1=C(Cl)C([H])=C(\C([H])=C2/SC(=NC2=O)N([H])C2=C([H])C([H])=C(C([H])=C2[H])C([H])([H])C([H])([H])[H])C([H])=C1[H] [H]N(C1=NC(=O)\C(S1)=C(\[H])C1=C([H])C(OC([H])([H])C([H])([H])[H])=C(OC([H])([H])C(=O)OC([H])([H])C([H])([H])[H])C(Cl)=C1[H])C1=C([H])C([H])=C(F)C([H])=C1[H] [H]OC(=O)C([H])([H])OC1=C(OC([H])([H])C([H])([H])[H])C([H])=C(\C([H])=C2\SC(=NC2=O)N([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])=C1I [H]OC(=O)C([H])([H])OC1=C(OC([H])([H])C([H])([H])[H])C([H])=C(\C([H])=C2\SC(=NC2=O)N([H])C2=C([H])C3=C([H])C([H])=C([H])C([H])=C3C([H])=C2[H])C([H])=C1Cl [H]OC(=O)C([H])([H])OC1=C(Cl)C([H])=C(\C([H])=C2/SC(=O)N(C2=O)C([H])([H])C(=O)N([H])C2=C([H])C([H])=C(C([H])=C2[H])C([H])([H])[H])C([H])=C1Cl [H]N(C(=O)C([H])([H])N1C(=O)S\C(=C(\[H])C2=C([H])C(OC([H])([H])C([H])([H])[H])=C(OC([H])([H])C(=O)OC([H])([H])[H])C(Cl)=C2[H])C1=O)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H] [H]N(C(=O)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C1=C([H])C2=C(N=C(C3=C([H])C([H])=C([H])O3)C(=N2)C2=C([H])C([H])=C([H])O2)C([H])=C1[H] [H]N(C(=O)N1C([H])([H])[C@]2(C([H])([H])[H])C([H])([H])[C@@]1([H])C([H])([H])C(C([H])([H])[H])(C([H])([H])[H])C2([H])[H])C1=C([H])C2=C(N=C(C3=C([H])C([H])=C([H])O3)C(=N2)C2=C([H])C([H])=C([H])O2)C([H])=C1[H] [H]N(C(=O)N1C([H])([H])C([H])([H])C([H])([H])[C@@]([H])(C(=O)N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H])C1([H])[H])C1=C([H])C2=NC(C3=C([H])C([H])=C([H])O3)=C(N=C2C([H])=C1[H])C1=C([H])C([H])=C([H])O1 [H]N(C(=O)N([H])C([H])([H])C1=C([H])C2=C(OC([H])([H])O2)C([H])=C1[H])C1=C([H])C2=C(N=C(C3=C([H])C([H])=C([H])O3)C(=N2)C2=C([H])C([H])=C([H])O2)C([H])=C1[H] [H]N(C(=O)N([H])C1=C([H])C2=C(N=C(C3=C([H])C([H])=C([H])O3)C(=N2)C2=C([H])C([H])=C([H])O2)C([H])=C1[H])C1=C([H])C([H])=C(OC([H])([H])C([H])([H])[H])C([H])=C1[H] [H]N(C(=O)N([H])C([H])([H])[H])C1=C([H])C2=C(N=C(C3=C([H])C([H])=C([H])O3)C(=N2)C2=C([H])C([H])=C([H])O2)C([H])=C1[H] [H]N(C(=O)N([H])C([H])([H])C([H])([H])OC([H])([H])[H])C1=C([H])C2=C(N=C(C3=C([H])C([H])=C([H])O3)C(=N2)C2=C([H])C([H])=C([H])O2)C([H])=C1[H] [H]OC([H])([H])C([H])([H])N([H])C(=O)N([H])C1=C([H])C2=C(N=C(C3=C([H])C([H])=C([H])O3)C(=N2)C2=C([H])C([H])=C([H])O2)C([H])=C1[H] [H]N(C(=O)N([H])C1=C([H])C2=C(N=C(C3=C([H])C([H])=C([H])O3)C(=N2)C2=C([H])C([H])=C([H])O2)C([H])=C1[H])C1=C([H])C([H])=C(Cl)C([H])=C1[H] [H]N(C(=O)N([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C2=C(N=C(C3=C([H])C([H])=C([H])O3)C(=N2)C2=C([H])C([H])=C([H])O2)C([H])=C1[H] [H]N(C(=O)N([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C1=C([H])C2=C(N=C(C3=C([H])C([H])=C([H])O3)C(=N2)C2=C([H])C([H])=C([H])O2)C([H])=C1[H] [H]N(C(=O)N([H])C1=C([H])C([H])=C([H])C2=C([H])C([H])=C([H])C([H])=C12)C1=C([H])C2=C(N=C(C3=C([H])C([H])=C([H])O3)C(=N2)C2=C([H])C([H])=C([H])O2)C([H])=C1[H] [H]N(C(=O)N([H])C1=C([H])C2=C(N=C(C3=C([H])C([H])=C([H])O3)C(=N2)C2=C([H])C([H])=C([H])O2)C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H] [H]N(C(=S)N(C([H])([H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])C1=C([H])C(Cl)=C(OC([H])([H])[H])C([H])=C1[H] [H]S\C(N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])=C1\C([H])=C([H])C(=O)C(OC([H])([H])[H])=C1[H] [H]OC(=O)C([H])([H])OC1=C(OC([H])([H])[H])C([H])=C(\C([H])=C2/SC(=NC2=O)N([H])C2=C([H])C([H])=C(C([H])=C2[H])C([H])([H])C([H])([H])[H])C([H])=C1Br [H]N([H])C1=C(SC(=S)N1C1=C([H])C([H])=C([H])C(=C1[H])C([H])([H])[H])C(=O)N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H] [H]OC(=O)C([H])([H])C([H])([H])SC1=C([H])C(=C([H])N2C(=O)C3=C(SC(C(=O)OC([H])([H])C([H])([H])[H])=C3C([H])([H])[H])N=C12)C(=O)C1=C(O[H])C([H])=C([H])C(OC([H])([H])[H])=C1[H] [H]OC(=O)C([H])([H])SC1=C([H])C(=C([H])N2C(=O)C3=C(SC4=C3C([H])([H])C([H])([H])C([H])([H])C4([H])[H])N=C12)C(=O)C1=C([H])C([H])=C([H])C([H])=C1O[H] [H]OC(=O)C([H])([H])SC1=C([H])C(=C([H])N2C(=O)C3=C(SC([H])=C3C3=C([H])C([H])=C([H])C([H])=C3[H])N=C12)C(=O)C1=C([H])C([H])=C([H])C([H])=C1O[H] [H]N([H])S(=O)(=O)C1=C(Cl)C([H])=C([H])C(=C1[H])C(=O)N([H])[C@]1([H])C2=C([H])C([H])=C([H])C([H])=C2SC([H])([H])C1([H])[H] [H]S\C(N([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])=C1/C([H])=C([H])C(=O)C(OC([H])([H])[H])=C1[H] [H]OC(=O)C([H])([H])OC1=C(Cl)C([H])=C(\C([H])=C2/SC3=NC(=C(C(=O)OC([H])([H])C([H])([H])[H])[C@]([H])(N3C2=O)C2=C([H])C(OC([H])([H])[H])=C([H])C([H])=C2[H])C([H])([H])[H])C([H])=C1Cl [H]OC(=O)C1=C([H])C([H])=C(\C([H])=C2/S\C(N([H])C2=O)=C(/[H])C(=O)C2=C([H])C([H])=C([H])O2)C([H])=C1[H] [H]OC(=O)C([H])([H])OC1=C([H])C([H])=C(\C([H])=C2/SC(=NC2=O)N([H])C2=C([H])C([H])=C(C([H])=C2[H])C([H])([H])C([H])([H])[H])C([H])=C1[H] [H]N(C1=NC(=O)\C(S1)=C(/[H])C1=C([H])C([H])=C(OC([H])([H])C(=O)OC([H])([H])[H])C([H])=C1[H])C1=C([H])C([H])=C(F)C([H])=C1[H] [H]N(C(=O)C([H])([H])[H])[C@@]1([H])C(=O)N(C2=C1C([H])=C(Br)C([H])=C2[H])C([H])([H])[H] [H]C1=C(N(N=C1C([H])([H])[H])S(=O)(=O)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H])C([H])([H])[H] [H]N([H])S(=O)(=O)C1=C([H])C([H])=C(N([H])C(=S)N([H])C2=C([H])C3=C(C([H])=C2[H])C([H])([H])C([H])([H])C3([H])[H])C([H])=C1[H] [H]OC(=O)C1=C(Cl)C([H])=C([H])C(=C1[H])C1=C([H])C([H])=C(O1)C(\[H])=C1/SC(=S)N(C1=O)C([H])([H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H] [H]OC(=O)C([H])([H])OC1=C([H])C([H])=C([H])C([H])=C1\C([H])=N\N([H])C(=O)C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])SC(=N1)N([H])C1=C([H])C([H])=C(Cl)C([H])=C1[H] [H]OC(=O)C([H])([H])OC1=C([H])C([H])=C(N([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])=C1[H] [H]OC(=O)C1=C([H])C(N([H])C(=O)C([H])([H])C([H])([H])C([H])([H])N2C(=S)S\C(=C(/[H])C3=C([H])C([H])=C([H])C([H])=C3[H])C2=O)=C([H])C([H])=C1[H] [H]OC(=O)C1=C([H])C([H])=C(N([H])C(=O)C([H])([H])C([H])([H])C([H])([H])N2C(=S)S\C(=C(/[H])C3=C([H])C([H])=C([H])C([H])=C3[H])C2=O)C([H])=C1[H] [H]OC(=O)C1=C([H])C([H])=C(N([H])C(=O)C([H])([H])C([H])([H])C([H])([H])N2C(=S)S\C(=C(\[H])/C(=C(\[H])C3=C([H])C([H])=C([H])C([H])=C3[H])/C([H])([H])[H])C2=O)C([H])=C1[H] [H]OC(=O)C1=C([H])C(N([H])C(=O)C([H])([H])C([H])([H])C([H])([H])N2C(=S)S\C(=C(\[H])C3=C([H])C4=C(OC([H])([H])O4)C([H])=C3[H])C2=O)=C([H])C([H])=C1[H] [H]OC(=O)C1=C([H])C([H])=C(N([H])C(=O)C([H])([H])C([H])([H])C([H])([H])N2C(=S)S\C(=C(\[H])C3=C([H])C4=C(OC([H])([H])O4)C([H])=C3[H])C2=O)C([H])=C1[H] [H]OC(=O)C1=C([H])C(N([H])C(=O)C([H])([H])C([H])([H])C([H])([H])N2C(=S)S\C(=C(\[H])C3=C([H])C([H])=C(C([H])=C3[H])C([H])([H])[H])C2=O)=C([H])C([H])=C1[H] [H]OC(=O)C1=C([H])C([H])=C(N([H])C(=O)C([H])([H])C([H])([H])C([H])([H])N2C(=S)S\C(=C(\[H])C3=C([H])C([H])=C(C([H])=C3[H])C([H])([H])C([H])([H])[H])C2=O)C([H])=C1[H] [H]OC(=O)C1=C([H])C([H])=C(N([H])C(=O)C([H])([H])C([H])([H])C([H])([H])N2C(=S)S\C(=C(\[H])C3=C([H])C(OC([H])([H])[H])=C([H])C([H])=C3[H])C2=O)C([H])=C1[H] [H]OC(=O)C1=C(O[H])C([H])=C(N([H])C(=O)C([H])([H])C([H])([H])C([H])([H])N2C(=S)S\C(=C(\[H])C3=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C([H])=C3[H])C2=O)C([H])=C1[H] [H]OC(=O)C1=C(O[H])C([H])=C(N([H])C(=O)C([H])([H])C([H])([H])C([H])([H])N2C(=S)S\C(=C(\[H])C3=C([H])C4=C(OC([H])([H])O4)C([H])=C3[H])C2=O)C([H])=C1[H] [H]OC(=O)C1=C([H])C(N([H])C(=O)C(\C#N)=C(/[H])C2=C([H])C([H])=C(OC([H])([H])C3=C([H])C([H])=C(Br)C([H])=C3[H])C([H])=C2[H])=C([H])C([H])=C1[H] [H]OC(=O)C1=C([H])C(N([H])C(=O)C(\C#N)=C(/[H])C2=C([H])C([H])=C(OC([H])([H])C3=C([H])C([H])=C(F)C([H])=C3[H])C([H])=C2[H])=C([H])C([H])=C1[H] [H]OC(=O)C1=C([H])C(N([H])C(=O)C(\C#N)=C(/[H])C2=C([H])C(OC([H])([H])[H])=C(OC([H])([H])C3=C([H])C([H])=C(Cl)C([H])=C3[H])C([H])=C2[H])=C([H])C([H])=C1[H] [H]OC(=O)C1=C([H])C(N([H])C(=O)C(\C#N)=C(/[H])C2=C([H])C(OC([H])([H])[H])=C(OC([H])([H])C3=C([H])C([H])=C(C([H])=C3[H])C([H])([H])[H])C([H])=C2[H])=C([H])C([H])=C1[H] [H]OC(=O)C1=C([H])C(=C([H])C([H])=C1[H])N1C(=S)S\C(=C(/[H])C2=C([H])C(OC([H])([H])[H])=C(OC([H])([H])C3=C([H])C([H])=C(Cl)C([H])=C3[H])C([H])=C2[H])C1=O [H]OC(=O)C1=C([H])C(=C([H])C([H])=C1[H])N1C(=S)S\C(=C(/[H])C2=C([H])C(OC([H])([H])[H])=C(OC([H])([H])C3=C([H])C(=C([H])C([H])=C3[H])C(=O)O[H])C(Cl)=C2[H])C1=O [H]OC(=O)C1=C(O[H])C([H])=C2OC(=C(C3=C([H])N(N=N3)C([H])([H])C([H])([H])C([H])([H])C(=O)N([H])C3=C([H])C([H])=C([H])C4=C([H])C([H])=C([H])C([H])=C34)C2=C1[H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H] [H]OC(=O)C1=C(O[H])C([H])=C2OC(=C(C3=C([H])N(N=N3)C([H])([H])C([H])([H])C([H])([H])C(=O)N([H])C3=C([H])C([H])=C(Cl)C4=C([H])C([H])=C([H])C([H])=C34)C2=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H] [H]OC(=O)C1=C(O[H])C([H])=C2OC(=C(C3=C([H])N(N=N3)C([H])([H])C([H])([H])C([H])([H])C(=O)N([H])C3=C([H])C([H])=C([H])C4=C([H])C([H])=C([H])C([H])=C34)C2=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H] [H]OC(=O)C1=C(O[H])C([H])=C2OC(=C(C3=C([H])N(N=N3)C([H])([H])C([H])([H])C([H])([H])C(=O)N([H])C3=NC4=C(S3)C([H])=C(OC([H])([H])[H])C([H])=C4[H])C2=C1[H])C1=C([H])C(=C([H])C([H])=C1[H])C([H])([H])[H] [H]C1=NN(C2=NC(=O)N(C(=O)C2=N1)C([H])([H])[H])C([H])([H])[H] [H]C([H])([H])N1N=C(N=C2C(=O)N(C(=O)N=C12)C([H])([H])[H])C([H])([H])[H] [H]C([H])=C([H])C([H])([H])C1=C([H])C([H])=C([H])C2=C1OC(=O)C(=C2[H])C(=O)N([H])C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)N([H])C1=NN=C(S1)C([H])([H])C([H])([H])[H] [H]C1=C([H])C([H])=C(C([H])=C1[H])C1=NN(C2=NC(=O)N(C(=O)C2=N1)C([H])([H])[H])C([H])([H])C([H])([H])[H] [H]OC(=O)C([H])([H])C([H])([H])N1C(=S)S\C(C1=O)=C1/C(=O)N(C2=C([H])C([H])=C([H])C([H])=C12)C([H])([H])C(=O)N([H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H] [H]C([H])([H])N1N=C(N=C2C(=O)N(C(=O)N=C12)C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[H] [H]OC(=O)C1=C([H])C([H])=C(C([H])=C1[H])N1C(=O)C([H])([H])[C@@]([H])(S\C(=N\N=C(/[H])C2=C([H])C3=C(OC([H])([H])O3)C([H])=C2[H])N([H])[H])C1=O [H]N(C(=O)C1=C(Cl)C([H])=C([H])C(=C1[H])N1C([H])=NN=C1[H])C1=C(C([H])=C([H])C(=C1[H])C1=NC2=C([H])C([H])=C([H])C([H])=C2S1)C([H])([H])[H] [H]N(C1=NN=C(O1)C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])C1=NC2=C(OC([H])([H])[H])C([H])=C([H])C([H])=C2S1 [H]N(C(=O)C([H])([H])SC1=NC2=C([H])C([H])=C([H])C([H])=C2C([H])=C1[H])C1=NSC(=N1)C1=C([H])C([H])=C(Cl)C([H])=C1[H] [H]N1N=C(SC([H])([H])C(=O)N2C3=C([H])C([H])=C([H])C([H])=C3C([H])([H])C2([H])[H])N(\C1=C1/C([H])=NC2=C([H])C([H])=C([H])C([H])=C12)C1=C([H])C([H])=C(OC([H])([H])C([H])([H])[H])C([H])=C1[H] [H]N([H])S(=O)(=O)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])N([H])C1=NC2=C(N=NN2C2=C([H])C([H])=C([H])C([H])=C12)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H] [H]N(C(=O)C1=C([H])C(=NC2=C1C([H])=C(Br)C([H])=C2[H])C1=C([H])C([H])=NC([H])=C1[H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1OC([H])([H])[H] [H]N(C(=O)C1=C([H])C(=NC2=C1C([H])=C(C([H])=C2[H])C([H])([H])[H])C1=C([H])C([H])=NC([H])=C1[H])C1=C([H])C([H])=C(OC([H])(F)F)C([H])=C1[H] [H]N(C(=O)C1=C([H])C(=NC2=C1C([H])=C(Br)C([H])=C2[H])C1=C([H])C([H])=C([H])C([H])=N1)C1=C([H])C([H])=NC([H])=C1[H] [H]N(C(=O)C1=C([H])C2=C(OC([H])([H])C([H])([H])O2)C([H])=C1[H])C1=C([H])C2=C(OC(=N2)C2=C([H])N=C([H])C([H])=C2[H])C([H])=C1[H] [H]N(C(=O)C([H])([H])N1C(=O)N([H])[C@](C1=O)(C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])[H])C1=C(C([H])=C(S1)C1=C([H])C([H])=C([H])C([H])=C1[H])C(=O)OC([H])([H])C([H])([H])[H] [H]C1=NC(C#CC2=C([H])C3=C(C([H])=C2[H])C(=O)C2=C([H])C([H])=C([H])C([H])=C2N3C([H])([H])[H])=C([H])C([H])=C1[H] [H]OC(=O)C([H])([H])OC1=C(OC([H])([H])[H])C([H])=C(\C([H])=C2/SC3=NC(=C(C(=O)OC([H])([H])C([H])([H])[H])[C@@]([H])(N3C2=O)C2=C(Cl)C([H])=C([H])C([H])=C2[H])C([H])([H])[H])C([H])=C1C([H])([H])[H] [H]OC(=O)C([H])([H])OC1=C([H])C([H])=C(\C([H])=C2/SC3=NC(=C(C(=O)OC([H])([H])C([H])([H])[H])[C@@]([H])(N3C2=O)C2=C([H])C(OC([H])([H])[H])=C([H])C([H])=C2[H])C([H])([H])[H])C([H])=C1[H] [H]N(C(=O)C([H])([H])SC1=NC2=C(C(=C(S2)C([H])([H])[H])C([H])([H])[H])C(=O)N1[H])C1=NC2=C(S1)C([H])=C(OC([H])([H])C([H])([H])[H])C([H])=C2[H] [H]N(C(=O)C([H])([H])SC1=NC2=C(C(=C([H])C([H])=C2C([H])=C1C#N)C([H])([H])[H])C([H])([H])[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H] [H]N(C(=O)C1=C(Cl)C2=C([H])C([H])=C([H])C([H])=C2S1)C1=NC2=C(S1)C([H])=C([H])C(=C2[H])C([H])([H])[H] OC(=O)C1=CC2=C(OC(=C2C#CC2=CC=C(OC(F)(F)F)C=C2)C2=CC=CC=C2)C=C1O OC(=O)C1=CC2=C(OC(=C2C#CC2=CC=CC(=C2)C(F)(F)F)C2=CC=CC=C2)C=C1O OC(=O)C1=CC2=C(OC(=C2C#CC2=CC(F)=CC(F)=C2)C2=CC=CC=C2)C=C1O