[H]C1=NC(=C([H])C([H])=C1[H])C1=C(N2C(SC([H])([H])C2([H])[H])=N1)C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]N1C(=NC(=C1C1=C([H])C([H])=C([H])C([H])=N1)C1=C([H])C2=C(OC([H])([H])O2)C([H])=C1[H])C1=C([H])C([H])=C(C#N)C([H])=C1[H]
[H]C1=NC(=C([H])C([H])=C1[H])C1=C(N2C(=N1)C([H])([H])C([H])([H])C2([H])[H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]OC(=O)C1=C([H])C([H])=C(C([H])=C1[H])C1=NC(=C(N1[H])C1=C([H])C([H])=C([H])C([H])=N1)C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]OC([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC(=C(N1[H])C1=C([H])C([H])=C([H])C([H])=N1)C1=C([H])C2=C(OC([H])([H])O2)C([H])=C1[H]
[H]C1=NC(=C([H])C([H])=C1[H])C1=C(N2C(=N1)C([H])([H])C([H])([H])C2([H])[H])C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]OC(=O)C1=C([H])C([H])=C(C([H])=C1[H])C1=NC(=C(N1[H])C1=C([H])C([H])=NC([H])=C1[H])C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]C1=NC(=C([H])C([H])=C1[H])C1=C(N2C(=N1)C([H])([H])C([H])([H])C2([H])[H])C1=C([H])C2=C(OC([H])([H])O2)C([H])=C1[H]
[H]OC(=O)C1=C([H])C([H])=C(C([H])=C1[H])C1=NC(=C(N1[H])C1=C([H])C([H])=C([H])C([H])=N1)C1=C([H])C2=C(OC([H])([H])O2)C([H])=C1[H]
[H]N([H])C(=O)C1=C([H])C([H])=C(C([H])=C1[H])C1=NC(=C(N1[H])C1=C([H])C([H])=C([H])C([H])=N1)C1=C([H])C([H])=C2OC([H])([H])OC2=C1[H]
[H]N1N=C([H])C(=C1C1=NC(=C([H])C([H])=C1[H])C([H])([H])[H])C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]N1N=C(C(=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=N1
[H]N1N=C([H])C(=C1C1=NC(=C([H])C([H])=C1[H])C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C1=C(C(=NN1C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=N1)C1=C([H])C([H])=NC2=C1C([H])=C([H])C([H])=C2[H]
[H]N1N=C([H])C(=C1C1=NC([H])=C(F)C([H])=C1[H])C1=C([H])C([H])=NC2=C1C([H])=C([H])C([H])=C2[H]
[H]N1N=C(C(=C1[H])C1=C([H])C([H])=C([H])C([H])=N1)C1=C2C([H])=C([H])C([H])=C([H])C2=NC([H])=C1[H]
[H]N1N=C(C(=C1C1=NC(=C([H])C([H])=C1[H])C([H])([H])[H])C1=C([H])C([H])=NC2=C1C([H])=C([H])C([H])=C2[H])C([H])([H])[H]
[H]N1N=C(C(=C1[H])C1=C([H])C([H])=NC2=C1C([H])=C([H])C([H])=C2[H])C1=NC([H])=C([H])C([H])=C1[H]
[H]N1N=C([H])C(=C1C1=NC([H])=C(Cl)C([H])=C1[H])C1=C([H])C([H])=NC2=C1C([H])=C([H])C([H])=C2[H]
[H]N1N=C(C(=C1[H])C1=C([H])C([H])=C(F)C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=N1
[H]N1N=C([H])C(=C1C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=NC2=C1C([H])=C([H])C([H])=C2[H]
[H]N1N=C(C2=C([H])C([H])=C([H])S2)C(=C1[H])C1=C([H])C([H])=NC2=C1C([H])=C([H])C([H])=C2[H]
[H]C1=C(C(=NN1C([H])([H])[H])C1=C([H])C([H])=C([H])C(=N1)C([H])([H])[H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]N1N=C([H])C(=C1C1=NC(=C([H])C([H])=C1[H])C([H])([H])[H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]N1N=C([H])C(=C1C1=NC(=C([H])C([H])=C1[H])C([H])([H])[H])C1=C([H])C(F)=C(F)C([H])=C1[H]
[H]N1N=C([H])C(=C1C1=C([H])C(=C([H])C([H])=C1[H])C(F)(F)F)C1=C([H])C([H])=NC2=C1C([H])=C([H])C([H])=C2[H]
[H]N1N=C([H])C(=C1C1=NC(Br)=C([H])C([H])=C1[H])C1=C([H])C([H])=NC2=C1C([H])=C([H])C([H])=C2[H]
[H]N1N=C([H])C(=C1C1=NC(=C([H])C([H])=C1[H])C([H])([H])[H])C1=C([H])C([H])=NC2=C1C([H])=C([H])C([H])=C2[H]
[H]N1N=C(C(=C1C1=NC([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=NC2=C1C([H])=C([H])C([H])=C2[H])C1([H])C([H])([H])C1([H])[H]
[H]OC1=C([H])C([H])=C(C([H])=C1[H])C1=C(N([H])N=C1[H])C1=NC(=C([H])C([H])=C1[H])C([H])([H])[H]
[H]N1N=C([H])C(=C1C1=NC(=C([H])C([H])=C1[H])C([H])([H])[H])C1=NC2=C([H])C([H])=C([H])N=C2C([H])=C1[H]
[H]N([H])C1=NC(=C(S1)C1=NC2=C([H])C([H])=C([H])N=C2C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=N1
[H]N([H])C1=NC(=C(S1)C1=C([H])C([H])=NC2=C([H])C([H])=C([H])C([H])=C12)C1=C([H])C([H])=C([H])C([H])=N1
[H]N([H])C1=NC(=C(S1)C1=C([H])C([H])=NC2=C([H])C([H])=C([H])C([H])=C12)C1=C([H])C([H])=C(Cl)C([H])=N1
[H]N([H])C1=NC(C2=NC([H])=C([H])S2)=C(S1)C1=C([H])C([H])=NC2=C([H])C([H])=C([H])C([H])=C12
[H]N([H])C1=NC(=C(S1)C1=C2N=C(C([H])=C([H])C2=NC([H])=C1[H])C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=N1
[H]N([H])C1=NC(=C(S1)C1=C([H])C([H])=NC2=C([H])C([H])=C([H])C([H])=C12)C1=C([H])C(Cl)=C([H])C([H])=N1
[H]N([H])C1=NC(=C(S1)C1=NC2=C([H])C([H])=C([H])N=C2C([H])=C1[H])C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]N([H])C1=NC(=C(S1)C1=C([H])C([H])=NC2=NC([H])=C([H])C([H])=C12)C1=C([H])C([H])=C([H])C([H])=N1
[H]N([H])C1=NC(=C(S1)C1=NC2=C(C([H])=C([H])N=C2C([H])=C1[H])C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=N1
[H]N([H])C1=NC(=C(S1)C1=C([H])C([H])=NC2=C([H])C([H])=C([H])C([H])=C12)C1=C([H])C([H])=C([H])C([H])=C1F
[H]N1N=C([H])C(=C1C1=NC([H])=C([H])C([H])=C1[H])C1=NC2=C([H])C([H])=C([H])N=C2C([H])=C1[H]
[H]N([H])C1=NC(=C(S1)C1=NC2=C([H])C([H])=C([H])C([H])=C2C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=N1
[H]N([H])C1=NC(=C(S1)C1=NC2=C([H])C([H])=C([H])N=C2C([H])=C1[H])C1=C([H])C([H])=C([H])C(=N1)C([H])([H])[H]
[H]N([H])C1=NC(=C(S1)C1=NC2=C([H])C([H])=C([H])N=C2C([H])=C1[H])C1=C([H])C([H])=C([H])C(Cl)=C1[H]
[H]N([H])C1=NC(=C(S1)C1=C([H])C([H])=NC2=C([H])C([H])=C([H])C([H])=C12)C1=C([H])C([H])=C([H])N=C1[H]
[H]N1N=C(C(=C1[H])C1=C([H])C([H])=NC(=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])(C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=N1
[H]N1N=C(C(=C1[H])C1=C([H])C([H])=NC(=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C(=O)N1C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C([H])C([H])=N1
[H]N1N=C(C(=C1[H])C1=C([H])C(=NC([H])=C1[H])C1=C([H])C([H])=C(OC([H])([H])C([H])([H])C2([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=N1
[H]N1N=C(C(=C1[H])C1=C([H])C([H])=NC(=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C(=O)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C1=C([H])C([H])=C([H])C([H])=N1
[H]N1N=C(C(=C1[H])C1=C([H])C([H])=NC(=C1[H])C1=C([H])C(OC([H])([H])[H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=N1
[H]N1N=C(C(=C1[H])C1=C([H])C([H])=NC(=C1[H])C1=C([H])C([H])=C(Cl)C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=N1
[H]N1N=C(C(=C1[H])C1=C([H])C([H])=NC(=C1[H])C1=C([H])C([H])=C(F)C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=N1
[H]N1N=C(C(=C1[H])C1=C([H])C(=NC([H])=C1[H])C1=C([H])C([H])=C(OC([H])([H])C([H])([H])N2C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=N1
[H]N1N=C(C(=C1[H])C1=C([H])C([H])=NC(=C1[H])C1=C([H])C([H])=C(C#N)C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=N1
[H]N1N=C(C(=C1[H])C1=C([H])C([H])=NC(=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=N1
[H]N1N=C(C(=C1[H])C1=C([H])C([H])=NC(=C1[H])C1=C([H])C([H])=C(OC([H])([H])C([H])([H])N2C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=N1
[H]N(C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C(=C([H])C([H])=N1)C1=C([H])N([H])N=C1C1=C([H])C([H])=C([H])C([H])=N1)C1([H])C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]N1N=C(C(=C1[H])C1=C([H])C([H])=NC(=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C1=C([H])C([H])=C([H])C([H])=N1
[H]N(C(=O)C1([H])C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC([H])=C([H])C(=C1[H])C1=C([H])N([H])N=C1C1=C([H])C([H])=C([H])C([H])=N1
[H]N1N=C(C(=C1[H])C1=C([H])C(=NC([H])=C1[H])C1=C([H])C([H])=C(OC([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=N1
[H]N1N=C(C(=C1[H])C1=C([H])C(=NC([H])=C1[H])C1=C([H])C([H])=C(OC([H])([H])C(=O)C([H])([H])[H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=N1
[H]N1N=C(C(=C1[H])C1=C([H])C([H])=NC(=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=N1
[H]N1N=C(C(=C1[H])C1=C([H])C([H])=NC(=C1[H])C1=C(F)C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=N1
[H]N(C(=O)C1=C([H])C([H])=C(C([H])=C1[H])C1=NC([H])=C([H])C(=C1[H])C1=C([H])N([H])N=C1C1=C([H])C([H])=C([H])C([H])=N1)C1([H])C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]N1N=C(C(=C1[H])C1=C([H])C([H])=NC(=C1[H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=N1
[H]N1N=C(C(=C1[H])C1=C([H])C([H])=NC(=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C(F)(F)F)C1=C([H])C([H])=C([H])C([H])=N1
[H]N1N=C(C(=C1[H])C1=C([H])C([H])=NC(=C1[H])C1=C([H])C(=C([H])C([H])=C1[H])C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=N1
[H]N1N=C(C(=C1[H])C1=C([H])C(=NC([H])=C1[H])C1=C([H])C([H])=C(OC([H])([H])C([H])([H])Cl)C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=N1
[H]N1N=C(C(=C1[H])C1=C([H])C(=NC([H])=C1[H])C1=C([H])C(=C([H])C([H])=C1[H])C(F)(F)F)C1=C([H])C([H])=C([H])C([H])=N1
[H]N1N=C(C(=C1[H])C1=C([H])C([H])=NC(=C1[H])C1=C(C([H])=C([H])C([H])=C1[H])C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=N1
[H]N1N=C(C(=C1[H])C1=C([H])C(=NC([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C([H])C([H])=N1
[H]N1N=C(C(=C1[H])C1=C([H])C([H])=NC(=C1[H])C1=C(C([H])=C([H])C([H])=C1[H])C(F)(F)F)C1=C([H])C([H])=C([H])C([H])=N1
[H]N1N=C(C(=C1[H])C1=C([H])C([H])=NC(=C1[H])C1=C([H])C([H])=C(OC([H])([H])C([H])([H])N2C([H])=NC([H])=C2[H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=N1
[H]N1N=C(C(=C1[H])C1=C([H])C(=NC([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C(=O)N(C([H])([H])[H])C1([H])C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C1=C([H])C([H])=C([H])C([H])=N1
[H]N1N=C(C(=C1[H])C1=C([H])C([H])=NC(=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C(=O)OC([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=N1
[H]N(C(=O)C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C(=C([H])C([H])=N1)C1=C([H])N([H])N=C1C1=C([H])C([H])=C([H])C([H])=N1)C([H])([H])C([H])([H])OC([H])([H])[H]
[H]C1=NC2=C(C([H])=C(C([H])=C2[H])C2=C3N(N=C2C2=C([H])C([H])=C([H])C(=N2)C([H])([H])[H])C([H])([H])C([H])([H])C3([H])[H])N1C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N1C([H])=NC2=C1C([H])=C([H])C(=C2[H])C1=C2N(N=C1C1=C([H])C([H])=C([H])C(=N1)C([H])([H])[H])C([H])([H])C([H])([H])C2([H])[H]
[H]C1=NC2=C(C([H])=C(C([H])=C2[H])C2=C3N(N=C2C2=C([H])C([H])=C([H])C([H])=N2)C([H])([H])C([H])([H])C3([H])[H])N1C([H])([H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H]
[H]C1=NC2=C(C([H])=C([H])C(=C2[H])C2=C3N(N=C2C2=C([H])C([H])=C([H])C([H])=N2)C([H])([H])C([H])([H])C3([H])[H])N1C([H])([H])C([H])([H])C([H])([H])O[C@@]1([H])OC([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]C1=NC2=C(C([H])=C([H])C(=C2[H])C2=C3N(N=C2C2=C([H])C([H])=C([H])C(=N2)C([H])([H])[H])C([H])([H])C([H])([H])C3([H])[H])N1C([H])([H])C([H])([H])C([H])([H])O[C@@]1([H])OC([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]C1=NC2=C(C([H])=C(C([H])=C2[H])C2=C3N(N=C2C2=C([H])C([H])=C([H])C(=N2)C([H])([H])[H])C([H])([H])C([H])([H])C3([H])[H])N1C([H])([H])[H]
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[H]N([H])C(=O)C1=C([H])C(N([H])C2=NC(=NC3=C([H])C([H])=C([H])C([H])=C23)C2=C([H])C([H])=C([H])C(=N2)C([H])([H])[H])=C([H])C([H])=C1[H]
[H]N(C1=C([H])C([H])=NC([H])=N1)C1=NC(=NC2=C([H])C([H])=C([H])C([H])=C12)C1=C([H])C([H])=C([H])C(=N1)C([H])([H])[H]
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[H]N(C1=NC(=NC(=C1[H])C([H])([H])[H])C1=C([H])C([H])=C([H])C(=N1)C([H])([H])[H])C1=C([H])C([H])=NC([H])=C1[H]
[H]N(C1=NC(=NC2=C1C(=C([H])S2)C([H])([H])[H])C1=C([H])C([H])=C([H])C(=N1)C([H])([H])[H])C1=C([H])C([H])=NC([H])=C1[H]
[H]N(C1=NC(=NC2=C1SC([H])=C2[H])C1=C([H])C([H])=C([H])C(=N1)C([H])([H])[H])C1=C([H])C([H])=NC([H])=C1[H]
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[H]N(C(=S)N1N=C(C(=C1[H])C1=C([H])N2N=C([H])N=C2C([H])=C1[H])C1=C([H])C([H])=C([H])C(=N1)C([H])([H])[H])C1=C([H])C([H])=C(OC([H])([H])[H])C(OC([H])([H])[H])=C1[H]
[H]N(C(=S)N1N=C(C(=C1[H])C1=C([H])N2N=C([H])N=C2C([H])=C1[H])C1=C([H])C([H])=C([H])C(=N1)C([H])([H])[H])C1=C([H])C(=C([H])C(=C1[H])C(F)(F)F)C(F)(F)F
[H]N(C(=S)N1N=C(C(=C1[H])C1=C([H])N2N=C([H])N=C2C([H])=C1[H])C1=C([H])C([H])=C([H])C(=N1)C([H])([H])[H])C1=C([H])C(=C([H])C(=C1[H])C([H])([H])[H])C([H])([H])[H]
[H]N(C(=S)N1N=C(C(=C1[H])C1=C([H])N2N=C([H])N=C2C([H])=C1[H])C1=C([H])C([H])=C([H])C(=N1)C([H])([H])[H])C1=C([H])C([H])=C(C(=C1[H])C([H])([H])[H])C([H])([H])[H]
[H]N(C(=S)N1N=C(C(=C1[H])C1=C([H])N2N=C([H])N=C2C([H])=C1[H])C1=C([H])C([H])=C([H])C(=N1)C([H])([H])[H])C1=C([H])C(Cl)=C([H])C(Cl)=C1[H]
[H]N(C(=S)N1N=C(C(=C1[H])C1=C([H])N2N=C([H])N=C2C([H])=C1[H])C1=C([H])C([H])=C([H])C(=N1)C([H])([H])[H])C1=C([H])C([H])=C(Cl)C(Cl)=C1[H]
[H]N(C(=S)N1N=C(C(=C1[H])C1=C([H])N2N=C([H])N=C2C([H])=C1[H])C1=C([H])C([H])=C([H])C(=N1)C([H])([H])[H])C1=C([H])C(F)=C([H])C(F)=C1[H]
[H]N(C(=S)N1N=C(C(=C1[H])C1=C([H])N2N=C([H])N=C2C([H])=C1[H])C1=C([H])C([H])=C([H])C(=N1)C([H])([H])[H])C1=C([H])C([H])=C(F)C(F)=C1[H]
[H]N(C(=S)N1N=C(C(=C1[H])C1=C([H])N2N=C([H])N=C2C([H])=C1[H])C1=C([H])C([H])=C([H])C(=N1)C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1OC(F)(F)F
[H]N(C(=S)N1N=C(C(=C1[H])C1=C([H])N2N=C([H])N=C2C([H])=C1[H])C1=C([H])C([H])=C([H])C(=N1)C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1OC([H])([H])[H]
[H]N(C(=S)N1N=C(C(=C1[H])C1=C([H])N2N=C([H])N=C2C([H])=C1[H])C1=C([H])C([H])=C([H])C(=N1)C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1C([H])([H])[H]
[H]N(C(=S)N1N=C(C(=C1[H])C1=C([H])N2N=C([H])N=C2C([H])=C1[H])C1=C([H])C([H])=C([H])C(=N1)C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1Cl
[H]N(C(=S)N1N=C(C(=C1[H])C1=C([H])N2N=C([H])N=C2C([H])=C1[H])C1=C([H])C([H])=C([H])C(=N1)C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1F
[H]N([H])C(=O)C1=C([H])C([H])=C(N([H])C(=S)N2N=C(C(=C2[H])C2=C([H])N3N=C([H])N=C3C([H])=C2[H])C2=C([H])C([H])=C([H])C(=N2)C([H])([H])[H])C([H])=C1[H]
[H]N(C(=S)N1N=C(C(=C1[H])C1=C([H])N2N=C([H])N=C2C([H])=C1[H])C1=C([H])C([H])=C([H])C(=N1)C([H])([H])[H])C1=C([H])C([H])=C(C#N)C([H])=C1[H]
[H]N(C(=S)N1N=C(C(=C1[H])C1=C([H])N2N=C([H])N=C2C([H])=C1[H])C1=C([H])C([H])=C([H])C(=N1)C([H])([H])[H])C1=C([H])C([H])=C(OC(F)(F)F)C([H])=C1[H]
[H]N(C(=S)N1N=C(C(=C1[H])C1=C([H])N2N=C([H])N=C2C([H])=C1[H])C1=C([H])C([H])=C([H])C(=N1)C([H])([H])[H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]N(C(=S)N1N=C(C(=C1[H])C1=C([H])N2N=C([H])N=C2C([H])=C1[H])C1=C([H])C([H])=C([H])C(=N1)C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C(F)(F)F
[H]N(C(=S)N1N=C(C(=C1[H])C1=C([H])N2N=C([H])N=C2C([H])=C1[H])C1=C([H])C([H])=C([H])C(=N1)C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H]
[H]N(C(=S)N1N=C(C(=C1[H])C1=C([H])N2N=C([H])N=C2C([H])=C1[H])C1=C([H])C([H])=C([H])C(=N1)C([H])([H])[H])C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]N([H])C(=O)C1=C([H])C([H])=C([H])C(N([H])C(=S)N2N=C(C(=C2[H])C2=C([H])N3N=C([H])N=C3C([H])=C2[H])C2=C([H])C([H])=C([H])C(=N2)C([H])([H])[H])=C1[H]
[H]N(C(=S)N1N=C(C(=C1[H])C1=C([H])N2N=C([H])N=C2C([H])=C1[H])C1=C([H])C([H])=C([H])C(=N1)C([H])([H])[H])C1=C([H])C(C#N)=C([H])C([H])=C1[H]
[H]N(C(=S)N1N=C(C(=C1[H])C1=C([H])N2N=C([H])N=C2C([H])=C1[H])C1=C([H])C([H])=C([H])C(=N1)C([H])([H])[H])C1=C([H])C(OC(F)(F)F)=C([H])C([H])=C1[H]
[H]N(C(=S)N1N=C(C(=C1[H])C1=C([H])N2N=C([H])N=C2C([H])=C1[H])C1=C([H])C([H])=C([H])C(=N1)C([H])([H])[H])C1=C([H])C(OC([H])([H])[H])=C([H])C([H])=C1[H]
[H]N(C(=S)N1N=C(C(=C1[H])C1=C([H])N2N=C([H])N=C2C([H])=C1[H])C1=C([H])C([H])=C([H])C(=N1)C([H])([H])[H])C1=C([H])C(=C([H])C([H])=C1[H])C(F)(F)F
[H]N(C(=S)N1N=C(C(=C1[H])C1=C([H])N2N=C([H])N=C2C([H])=C1[H])C1=C([H])C([H])=C([H])C(=N1)C([H])([H])[H])C1=C([H])C(=C([H])C([H])=C1[H])C([H])([H])[H]
[H]N(C(=S)N1N=C(C(=C1[H])C1=C([H])N2N=C([H])N=C2C([H])=C1[H])C1=C([H])C([H])=C([H])C(=N1)C([H])([H])[H])C1=C([H])C(Cl)=C([H])C([H])=C1[H]
[H]N(C(=S)N1N=C(C(=C1[H])C1=C([H])N2N=C([H])N=C2C([H])=C1[H])C1=C([H])C([H])=C([H])C(=N1)C([H])([H])[H])C1=C([H])C(F)=C([H])C([H])=C1[H]
[H]N(C(=S)N1N=C(C(=C1[H])C1=C([H])N2N=C([H])N=C2C([H])=C1[H])C1=C([H])C([H])=C([H])C(=N1)C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=S)N1N=C(C(=C1[H])C1=C([H])N2N=C([H])N=C2C([H])=C1[H])C1=C([H])C([H])=C([H])C(=N1)C([H])([H])[H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]N(C(=O)C([H])([H])N1N=C(C(=C1[H])C1=C([H])C([H])=C2N=C([H])C([H])=NC2=C1[H])C1=C([H])C([H])=C([H])C(=N1)C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)C([H])([H])N1N=C(C(=C1[H])C1=C([H])C([H])=C2N=C(C(=NC2=C1[H])C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C([H])C(=N1)C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)C([H])([H])N1N=C(C(=C1[H])C1=C([H])C([H])=C2N=C([H])C([H])=NC2=C1[H])C1=C([H])C([H])=C([H])C(=N1)C([H])([H])[H])C1=C([H])C(C#N)=C([H])C([H])=C1[H]
[H]N(C(=O)C([H])([H])N1N=C(C(=C1[H])C1=C([H])C([H])=C2N=C(C(=NC2=C1[H])C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C([H])C(=N1)C([H])([H])[H])C1=C([H])C(C#N)=C([H])C([H])=C1[H]
[H]N(C(=O)C([H])([H])N1N=C([H])C(=C1C1=C([H])C([H])=C([H])C(=N1)C([H])([H])[H])C1=C([H])C([H])=C2N=C([H])C([H])=NC2=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)C([H])([H])N1N=C([H])C(=C1C1=C([H])C([H])=C([H])C(=N1)C([H])([H])[H])C1=C([H])C([H])=C2N=C(C(=NC2=C1[H])C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)C([H])([H])N1N=C([H])C(=C1C1=C([H])C([H])=C([H])C(=N1)C([H])([H])[H])C1=C([H])C([H])=C2N=C([H])C([H])=NC2=C1[H])C1=C([H])C([H])=C([H])C(C#N)=C1[H]
[H]N(C(=O)C([H])([H])N1N=C([H])C(=C1C1=C([H])C([H])=C([H])C(=N1)C([H])([H])[H])C1=C([H])C([H])=C2N=C(C(=NC2=C1[H])C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C([H])C(C#N)=C1[H]
[H]N(C(=O)C([H])([H])C([H])([H])N1N=C(C(=C1[H])C1=C([H])C([H])=C2N=C([H])C([H])=NC2=C1[H])C1=C([H])C([H])=C([H])C(=N1)C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)C([H])([H])C([H])([H])N1N=C(C(=C1[H])C1=C([H])C([H])=C2N=C(C(=NC2=C1[H])C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C([H])C(=N1)C([H])([H])[H])C1=C([H])C(C#N)=C([H])C([H])=C1[H]
[H]N(C(=S)C([H])([H])N1N=C(C(=C1[H])C1=C([H])C([H])=C2N=C([H])C([H])=NC2=C1[H])C1=C([H])C([H])=C([H])C(=N1)C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=S)C([H])([H])N1N=C(C(=C1[H])C1=C([H])C([H])=C2N=C(C(=NC2=C1[H])C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C([H])C(=N1)C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=S)C([H])([H])N1N=C(C(=C1[H])C1=C([H])C([H])=C2N=C([H])C([H])=NC2=C1[H])C1=C([H])C([H])=C([H])C(=N1)C([H])([H])[H])C1=C([H])C(C#N)=C([H])C([H])=C1[H]
[H]N(C(=S)C([H])([H])N1N=C(C(=C1[H])C1=C([H])C([H])=C2N=C(C(=NC2=C1[H])C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C([H])C(=N1)C([H])([H])[H])C1=C([H])C(C#N)=C([H])C([H])=C1[H]
[H]N([H])C(=O)C1=C([H])C([H])=C([H])C(N([H])C(=O)C([H])([H])N2N=C(C(=C2[H])C2=C([H])C([H])=C3N=C([H])C([H])=NC3=C2[H])C2=C([H])C([H])=C([H])C(=N2)C([H])([H])[H])=C1[H]
[H]N([H])C(=O)C1=C([H])C([H])=C([H])C(N([H])C(=O)C([H])([H])N2N=C(C(=C2[H])C2=C([H])C([H])=C3N=C(C(=NC3=C2[H])C([H])([H])[H])C([H])([H])[H])C2=C([H])C([H])=C([H])C(=N2)C([H])([H])[H])=C1[H]
[H]N(C1=NC([H])=C([H])C(=N1)C1=C(N=C(S1)C([H])(C([H])([H])[H])C([H])([H])[H])C1=C([H])C(N([H])S(=O)(=O)C2=C(F)C([H])=C([H])C([H])=C2F)=C(F)C([H])=C1[H])C1=C([H])C([H])=C(N=C1[H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]N(C1=C([H])C([H])=C2OC(C(=O)N([H])C2=N1)(C([H])([H])[H])C([H])([H])[H])C1=C(F)C([H])=NC(=N1)N([H])C1=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C(OC([H])([H])[H])=C1[H]
[H]N([H])C(=O)C1=C([H])C([H])=C(C([H])=C1[H])C1=NC(C2=NC(=C([H])S2)C([H])([H])C([H])([H])[H])=C(N1[H])C1=C([H])C2=C(OC([H])([H])O2)C([H])=C1[H]
[H]N([H])C(=O)C1=C([H])C([H])=C(C([H])=C1[H])C1=NC(C2=NC(Br)=C([H])S2)=C(N1[H])C1=C([H])C2=C(OC([H])([H])O2)C([H])=C1[H]
[H]N([H])C(=O)C1=C([H])C([H])=C(C([H])=C1[H])C1=NC(C2=C([H])SC(=N2)C([H])([H])[H])=C(N1[H])C1=C([H])C2=C(OC([H])([H])O2)C([H])=C1[H]
[H]N([H])C([H])([H])C1=NC(C2=NC(=C([H])S2)C([H])([H])[H])=C(N1[H])C1=C([H])C2=C(OC([H])([H])O2)C([H])=C1[H]
[H]N([H])C([H])([H])C([H])([H])C1=NC(C2=NC(=C([H])S2)C([H])([H])[H])=C(N1[H])C1=C([H])C2=C(OC([H])([H])O2)C([H])=C1[H]
[H]N([H])C([H])([H])C([H])([H])C([H])([H])C1=NC(C2=NC(=C([H])S2)C([H])([H])[H])=C(N1[H])C1=C([H])C2=C(OC([H])([H])O2)C([H])=C1[H]
[H]N(C(=O)C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=NC(C2=NC(=C([H])S2)C([H])([H])[H])=C(N1[H])C1=C([H])C2=C(OC([H])([H])O2)C([H])=C1[H]
[H]N(C(=O)C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C1=NC(C2=NC(=C([H])S2)C([H])([H])[H])=C(N1[H])C1=C([H])C2=C(OC([H])([H])O2)C([H])=C1[H]
[H]N(C(=O)C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C1=NC(C2=NC(=C([H])S2)C([H])([H])[H])=C(N1[H])C1=C([H])C2=C(OC([H])([H])O2)C([H])=C1[H]
[H]N(C(=O)C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C1=NC(C2=NC(=C([H])S2)C([H])([H])[H])=C(N1[H])C1=C([H])C2=C(OC([H])([H])O2)C([H])=C1[H]
[H]N(C(=O)C1=NC(C2=NC(=C([H])S2)C([H])([H])[H])=C(N1[H])C1=C([H])C2=C(OC([H])([H])O2)C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)C1=NC(C2=NC(=C([H])S2)C([H])([H])[H])=C(N1[H])C1=C([H])C2=C(OC([H])([H])O2)C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]N(C(=O)C([H])([H])C([H])([H])C1=NC(C2=NC(=C([H])S2)C([H])([H])[H])=C(N1[H])C1=C([H])C2=C(OC([H])([H])O2)C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])[H]
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[H]N([H])C1=NN([H])C2=C1C([H])=C([H])C(=C2[H])C1=C([H])C(=NC(=N1)N([H])[H])N(C([H])([H])[H])C([H])([H])[H]
[H]C1=NN(C(=C1[H])C1=C([H])C2=C(N=C([H])N(C2=O)C([H])([H])[H])C([H])=C1[H])C1=NC(=C([H])C([H])=C1[H])C([H])([H])[H]
[H]C([H])=C([H])N1C([H])=NC2=C(C([H])=C(C([H])=C2[H])C2=C([H])C([H])=NN2C2=NC(=C([H])C([H])=C2[H])C([H])([H])[H])C1=O
[H]C1=NN(C(=C1C([H])([H])[H])C1=C([H])C2=C(N=C([H])N(C2=O)C([H])([H])[H])C([H])=C1[H])C1=NC(=C([H])C([H])=C1[H])C([H])([H])[H]
[H]C1=C(N(N=C1C([H])([H])[H])C1=NC(=C([H])C([H])=C1[H])C([H])([H])[H])C1=C([H])C2=C(N=C([H])N(C2=O)C([H])([H])[H])C([H])=C1[H]
[H]N1C([H])=NC2=C(C([H])=C(C([H])=C2[H])C2=C(C([H])=NN2C2=NC(=C([H])C([H])=C2[H])C([H])([H])[H])C([H])([H])[H])C1=O
[H]C1=C(N(N=C1C([H])([H])C([H])([H])[H])C1=NC(=C([H])C([H])=C1[H])C([H])([H])[H])C1=C([H])C2=C(N=C([H])N(C2=O)C([H])([H])[H])C([H])=C1[H]
[H]N1C([H])=NC2=C(C([H])=C(C([H])=C2[H])C2=C([H])C([H])=NN2C2=NC(=C([H])C([H])=C2[H])C([H])([H])[H])C1=O
[H]N1C([H])=NC2=C(C([H])=C(C([H])=C2[H])C2=C(C([H])=NN2C2=NC(=C([H])C([H])=C2[H])C([H])([H])[H])C([H])([H])C([H])([H])[H])C1=O
[H]N1C([H])=NC2=C(C([H])=C(C([H])=C2[H])C2=C3C(=NN2C2=NC(=C([H])C([H])=C2[H])C([H])([H])[H])C([H])([H])C([H])([H])C3([H])[H])C1=O
[H]C1=NN(C(=C1[H])C1=C([H])C2=C(N=C([H])N(C2=O)C([H])([H])C([H])([H])[H])C([H])=C1[H])C1=NC(=C([H])C([H])=C1[H])C([H])([H])[H]
CC(C)(C)C1=NC(=C(S1)C1=NC(N)=NC=C1)C1=CC=CC(NS(=O)(=O)C2=C(F)C=CC=C2F)=C1F
[H][C@@]12C[C@@](O)(CO)[C@](C)(O1)N1C3=C(C=CC=C3)C3=C1C1=C(C4=C(C=CC=C4)N21)C1=C3CNC1=O
CC1=CC=CC(=N1)N1N=NC(CC2=CC=CC=C2)=C1C1=CC=C2N=CC=NC2=C1
CC(C)CCC1=C(N(N=N1)C1=NC(C)=CC=C1)C1=CC=C2N=CC=NC2=C1