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[H]N(C(=O)OC([H])([H])C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC2=C(C([H])=NN2C2([H])C([H])([H])C([H])([H])N(C([H])([H])C3=C([H])C([H])=C([H])C([H])=C3[H])C([H])([H])C2([H])[H])C(=N1)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]OC1=C([H])C(=C([H])C([H])=C1[H])C1=NC(N2C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])=C2C([H])=NN(C2=N1)C1([H])C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]OC1=C([H])C(=C([H])C([H])=C1[H])C1=NC2=C(C([H])=NN2C2([H])C([H])([H])C([H])([H])N(C([H])([H])C3=C([H])C([H])=C([H])N=C3[H])C([H])([H])C2([H])[H])C(=N1)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]OC1=C(C([H])=C([H])C([H])=C1[H])C1=NC2=C(C([H])=NN2C2([H])C([H])([H])C([H])([H])N(C([H])([H])C3=C([H])C([H])=C([H])C([H])=C3[H])C([H])([H])C2([H])[H])C(=N1)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]OC1=C([H])C([H])=C(C([H])=C1[H])C1=NC2=C(C([H])=NN2C2([H])C([H])([H])C([H])([H])N(C([H])([H])C3=C([H])C([H])=C([H])C([H])=C3[H])C([H])([H])C2([H])[H])C(=N1)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]N(C(=O)N([H])C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC2=C(C([H])=NN2C2([H])C([H])([H])C([H])([H])N([H])C([H])([H])C2([H])[H])C(=N1)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]N(C(=O)N([H])C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC2=C(C([H])=NN2C2([H])C([H])([H])C([H])([H])N(C([H])([H])C3=C([H])C([H])=C([H])C([H])=C3[H])C([H])([H])C2([H])[H])C(=N1)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]N(C(=O)N([H])C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC2=C(C([H])=NN2C2([H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C2([H])[H])C(=N1)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]N(C(=O)N([H])C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC2=C(C([H])=NN2C2([H])C([H])([H])C([H])([H])N(C(=O)C([H])([H])[H])C([H])([H])C2([H])[H])C(=N1)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]N(C(=O)N([H])C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC2=C(C([H])=NN2C2([H])C([H])([H])C([H])([H])N(C(=O)N([H])C([H])([H])[H])C([H])([H])C2([H])[H])C(=N1)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]N(C(=O)N([H])C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC2=C(C([H])=NN2C2([H])C([H])([H])C([H])([H])N(C(=O)N(C([H])([H])[H])C([H])([H])[H])C([H])([H])C2([H])[H])C(=N1)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]N(C(=O)N([H])C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC2=C(C([H])=NN2C2([H])C([H])([H])C([H])([H])N(C(=O)OC([H])([H])[H])C([H])([H])C2([H])[H])C(=N1)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]N(C(=O)N([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC2=C(C([H])=NN2C2([H])C([H])([H])C([H])([H])N(C(=O)C3=C([H])C([H])=C([H])N=C3[H])C([H])([H])C2([H])[H])C(=N1)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C1=C([H])C([H])=NC([H])=C1[H]
[H]N(C(=O)OC([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC2=C(C([H])=NN2C2([H])C([H])([H])C([H])([H])N(C(=O)OC([H])([H])[H])C([H])([H])C2([H])[H])C(=N1)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]OC([H])([H])C([H])([H])OC(=O)N([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC2=C(C([H])=NN2C2([H])C([H])([H])C([H])([H])N(C(=O)OC([H])([H])[H])C([H])([H])C2([H])[H])C(=N1)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]N(C(=O)N([H])C([H])([H])C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC2=C(C([H])=NN2C2([H])C([H])([H])C([H])([H])N(C(=O)OC([H])([H])[H])C([H])([H])C2([H])[H])C(=N1)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]N(C(=O)N([H])C([H])([H])C([H])([H])F)C1=C([H])C([H])=C(C([H])=C1[H])C1=NC2=C(C([H])=NN2C2([H])C([H])([H])C([H])([H])N(C(=O)OC([H])([H])[H])C([H])([H])C2([H])[H])C(=N1)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]N(C(=O)N([H])C1([H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC2=C(C([H])=NN2C2([H])C([H])([H])C([H])([H])N(C(=O)OC([H])([H])[H])C([H])([H])C2([H])[H])C(=N1)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]N(C(=O)N([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC2=C(C([H])=NN2C2([H])C([H])([H])C([H])([H])N(C(=O)OC([H])([H])[H])C([H])([H])C2([H])[H])C(=N1)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C1=C([H])C([H])=C([H])N=C1[H]
[H]N(C(=O)N([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC2=C(C([H])=NN2C2([H])C([H])([H])C([H])([H])N(C(=O)OC([H])([H])[H])C([H])([H])C2([H])[H])C(=N1)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C1=C([H])C([H])=NC([H])=C1[H]
[H]N(C(=O)N([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC2=C(C([H])=NN2C2([H])C([H])([H])C([H])([H])N(C(=O)OC([H])([H])[H])C([H])([H])C2([H])[H])C(=N1)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H]
[H]OC([H])([H])C1=C([H])C([H])=C(N([H])C(=O)N([H])C2=C([H])C([H])=C(C([H])=C2[H])C2=NC3=C(C([H])=NN3C3([H])C([H])([H])C([H])([H])N(C(=O)OC([H])([H])[H])C([H])([H])C3([H])[H])C(=N2)N2C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])C([H])=C1[H]
[H]C1=NN(C2=C1C(=NC(=N2)C1=C([H])C([H])=C([H])N=C1[H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]C1=NN(C2=C1C(=NC(=N2)C1=C([H])C([H])=NC([H])=C1[H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]C1=NN(C2=C1C(=NC(=N2)C1=C([H])C2=C(N=C1[H])C([H])=C([H])C([H])=C2[H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]C1=NN(C2=C1C(=NC(=N2)C1=C([H])C2=C(N=C([H])C([H])=C2[H])C([H])=C1[H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]OC([H])([H])C([H])([H])OC(=O)N([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC2=C(C([H])=NN2C2([H])C([H])([H])C([H])([H])N(C([H])([H])C3=C([H])C([H])=C([H])N=C3[H])C([H])([H])C2([H])[H])C(=N1)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]N(C(=O)N([H])C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC2=C(C([H])=NN2C2([H])C([H])([H])C([H])([H])N(C([H])([H])C3=C([H])C([H])=C([H])N=C3[H])C([H])([H])C2([H])[H])C(=N1)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]N1C(=O)N([H])C2=C1C([H])=C([H])C(=C2[H])C1=NC2=C(C([H])=NN2C2([H])C([H])([H])C([H])([H])N(C([H])([H])C3=C([H])C([H])=C([H])C([H])=C3[H])C([H])([H])C2([H])[H])C(=N1)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]N1C(=C([H])C2=C1C([H])=C([H])C([H])=C2[H])C1=NC2=C(C([H])=NN2C2([H])C([H])([H])C([H])([H])N(C([H])([H])C3=C([H])C([H])=C([H])C([H])=C3[H])C([H])([H])C2([H])[H])C(=N1)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]N1C([H])=C([H])C2=C1C([H])=C([H])C([H])=C2C1=NC2=C(C([H])=NN2C2([H])C([H])([H])C([H])([H])N(C([H])([H])C3=C([H])C([H])=C([H])C([H])=C3[H])C([H])([H])C2([H])[H])C(=N1)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]N1C([H])=C([H])C2=C([H])C(=C([H])C([H])=C12)C1=NC2=C(C([H])=NN2C2([H])C([H])([H])C([H])([H])N(C([H])([H])C3=C([H])C([H])=C([H])C([H])=C3[H])C([H])([H])C2([H])[H])C(=N1)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]N1C([H])=C([H])C2=C([H])C([H])=C(C([H])=C12)C1=NC2=C(C([H])=NN2C2([H])C([H])([H])C([H])([H])N(C([H])([H])C3=C([H])C([H])=C([H])C([H])=C3[H])C([H])([H])C2([H])[H])C(=N1)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]N1C([H])=C([H])C2=C1C(=C([H])C([H])=C2[H])C1=NC2=C(C([H])=NN2C2([H])C([H])([H])C([H])([H])N(C([H])([H])C3=C([H])C([H])=C([H])C([H])=C3[H])C([H])([H])C2([H])[H])C(=N1)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]C1=NN(C2=C1C(=NC(=N2)C1=C([H])C([H])=C2N(C([H])=C([H])C2=C1[H])C([H])([H])[H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N1C([H])=C([H])C2=C([H])C(=C([H])C([H])=C12)C1=NC2=C(C([H])=NN2C2([H])C([H])([H])C([H])([H])N([H])C([H])([H])C2([H])[H])C(=N1)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]N1C([H])=C([H])C2=C([H])C(=C([H])C([H])=C12)C1=NC2=C(C([H])=NN2C2([H])C([H])([H])C([H])([H])N(C([H])([H])C3=C([H])N=C([H])C([H])=C3[H])C([H])([H])C2([H])[H])C(=N1)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]N1C([H])=C([H])C2=C([H])C(=C([H])C([H])=C12)C1=NC2=C(C([H])=NN2C2([H])C([H])([H])C([H])([H])N(C(=O)C3=C([H])N=C([H])C([H])=C3[H])C([H])([H])C2([H])[H])C(=N1)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]O[C@]1([H])C([H])([H])C([H])([H])[C@@]([H])(C([H])([H])[C@@]([H])(C([H])([H])[H])[C@@]2([H])OC(=O)[C@@]3([H])N(C(=O)C(=O)[C@]4(O[H])O[C@@]([H])(C([H])([H])C([H])([H])[C@@]4([H])C([H])([H])[H])C([H])([H])[C@]([H])(OC([H])([H])[H])\C(=C(/[H])\C(\[H])=C(/[H])\C(\[H])=C([H])\[C@@]([H])(C([H])([H])[H])C([H])([H])[C@]([H])(C(=O)[C@]([H])(OC([H])([H])[H])[C@]([H])(O[H])\C(=C([H])\[C@]([H])(C(=O)C2([H])[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C3([H])[H])C([H])([H])[C@@]1([H])OC([H])([H])[H]
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[H]N(C(=O)N([H])C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC2=C(C([H])=NN2C([H])([H])C(F)(F)F)C(=N1)C1=C([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]N(C(=O)N([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC2=C(C([H])=NN2C([H])([H])C(F)(F)F)C(=N1)C1=C([H])C([H])([H])OC([H])([H])C1([H])[H])C1=C([H])C([H])=C([H])N=C1[H]
[H]N(C(=O)N([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC2=C(SC([H])=C2[H])C(=N1)C1=C([H])C([H])([H])OC([H])([H])C1([H])[H])C1=C([H])C([H])=NC([H])=C1[H]
[H]N(C(=O)N([H])C1=C([H])C2=C(O\C(=C(/[H])C3=C(N([H])C4=C([H])C([H])=C(OC([H])([H])[H])C([H])=C34)C3=C(N(N=C3C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C2=O)C([H])=C1[H])C1=C([H])N=C([H])C([H])=C1[H]
[H]N(C(=O)N([H])C([H])([H])[H])C1=C([H])C2=C(O\C(=C(/[H])C3=C(N([H])C4=C(F)C([H])=C(OC([H])([H])[H])C([H])=C34)C3=C(N(N=C3C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C2=O)C([H])=C1[H]
[H]N(C(=O)N([H])C1=C([H])C2=C(O\C(=C(/[H])C3=C(N([H])C4=C(F)C([H])=C(OC([H])([H])[H])C([H])=C34)C3=C(N(N=C3C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C2=O)C([H])=C1[H])C1=C([H])N=C([H])C([H])=C1[H]
[H]N(C(=O)N([H])C1=C([H])C2=C(O\C(=C(/[H])C3=C(N([H])C4=C([H])C([H])=C(OC([H])([H])[H])C([H])=C34)C3=C(N(N=C3C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C2=O)C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C(=O)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]N(C(=O)N([H])C1=C([H])C2=C(O\C(=C(/[H])C3=C(N([H])C4=C([H])C([H])=C(OC([H])([H])[H])C([H])=C34)C3=C(N(N=C3C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C2=O)C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C(=O)N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N(C(=O)N([H])C1=C([H])C2=C(O\C(=C(/[H])C3=C(N([H])C4=C(F)C([H])=C(OC([H])([H])[H])C([H])=C34)C3=C(N(N=C3C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C2=O)C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C(=O)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]N(C(=O)N([H])C1=C([H])C2=C(O\C(=C(/[H])C3=C(N([H])C4=C(F)C([H])=C(OC([H])([H])[H])C([H])=C34)C3=C(N(N=C3C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C2=O)C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C(=O)N(C([H])([H])[H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H]
[H]N(C(=O)N([H])C1=C([H])C2=C(O\C(=C(/[H])C3=C([H])N([H])C4=C([H])C([H])=C(OC([H])([H])[H])C([H])=C34)C2=O)C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C(=O)N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N(C(=O)N([H])C([H])([H])[H])C1=C([H])C2=C(O\C(=C(/[H])C3=C(N([H])C4=C([H])C([H])=C(OC([H])([H])[H])C([H])=C34)C3=C(N(N=C3C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C2=O)C([H])=C1[H]
[H]N(C(=O)N([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC(=NC(=N1)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)N([H])C([H])([H])C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC(=NC(=N1)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]N(C(=O)N([H])C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC(=NC(=N1)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]N(C(=O)N([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC(=NC(=N1)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]N(C(=O)N([H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC(=NC(=N1)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]N(C(=O)N([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC(=NC(=N1)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]N(C(=O)N([H])C1=C([H])C([H])=C(F)C([H])=C1F)C1=C([H])C([H])=C(C([H])=C1[H])C1=NC(=NC(=N1)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]OC([H])([H])C1=C([H])C([H])=C(N([H])C(=O)N([H])C2=C([H])C([H])=C(C([H])=C2[H])C2=NC(=NC(=N2)N2C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])N2C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])C([H])=C1[H]
[H]OC([H])([H])C([H])([H])C1=C([H])C([H])=C(N([H])C(=O)N([H])C2=C([H])C([H])=C(C([H])=C2[H])C2=NC(=NC(=N2)N2C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])N2C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])C([H])=C1[H]
[H]OC1=C(OC([H])([H])[H])C([H])=C(C([H])=C1OC([H])([H])[H])C1=C([H])N(C([H])=N1)C1=NC(=C([H])C([H])=N1)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]OC1=C(OC([H])([H])[H])C([H])=C(\C([H])=N\N([H])C2=NC(=NC(=N2)N2C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])N2C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])C([H])=C1OC([H])([H])[H]
[H]OC1=C(OC([H])([H])[H])C([H])=C(\C([H])=N\N([H])C2=NC(=NC(=N2)N2C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])N2C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])=C1OC([H])([H])[H]
[H]OC1=C(OC([H])([H])[H])C([H])=C(\C([H])=N\N([H])C2=NC(=NC(=C2[H])N2C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])N2C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])C([H])=C1OC([H])([H])[H]
[H]N1C([H])=NC2=C1N=C(N=C2N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C1=C([H])SC([H])=C1[H]
[H]N(C(=O)N([H])C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC(N2C([H])([H])[C@@]3([H])O[C@]([H])(C([H])([H])C3([H])[H])C2([H])[H])=C2C([H])=NN(C2=N1)C([H])([H])C(F)(F)F
[H]N(C(=O)N([H])C1([H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC(N2C([H])([H])[C@@]3([H])O[C@]([H])(C([H])([H])C3([H])[H])C2([H])[H])=C2C([H])=NN(C2=N1)C1([H])C([H])([H])C([H])([H])N(C(=O)OC([H])([H])[H])C([H])([H])C1([H])[H]
[H]OC1=C(OC([H])([H])[H])C([H])=C(C([H])=C1OC([H])([H])[H])C1=C([H])N(C([H])=N1)C1=NC(=NC([H])=C1[H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]OC1=C(OC([H])([H])[H])C([H])=C(C([H])=C1OC([H])([H])[H])C1=NC(=C([H])C([H])=C1[H])C1=NC(=NC([H])=C1[H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]OC1=C(OC([H])([H])[H])C([H])=C(C([H])=C1OC([H])([H])[H])C1=NC(=C([H])S1)C1=NC(=NC([H])=C1[H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]OC1=C(OC([H])([H])[H])C([H])=C(C([H])=C1OC([H])([H])[H])C1=C([H])SC(=N1)C1=NC(=NC([H])=C1[H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]OC1=C(OC([H])([H])[H])C([H])=C(C([H])=C1OC([H])([H])[H])C1=C([H])C([H])=C(O1)C1=NC(=NC([H])=C1[H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]OC1=C(OC([H])([H])[H])C([H])=C(C([H])=C1OC([H])([H])[H])C1=C([H])C([H])=C(O1)C1=NC(=NC(=C1[H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]OC1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C(O1)C1=NC(=NC(=C1[H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]OC1=C([H])C([H])=C([H])C(=C1[H])C1=C([H])C([H])=C(O1)C1=NC(=NC(=C1[H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]OC([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C(O1)C1=NC(=NC(=C1[H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]OC([H])([H])C1=C([H])C([H])=C([H])C(=C1[H])C1=C([H])C([H])=C(O1)C1=NC(=NC(=C1[H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]C1=C(OC(=C1[H])C1=C([H])C([H])=NC([H])=C1[H])C1=NC(=NC(=C1[H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]OC1=C(OC([H])([H])[H])C([H])=C(C([H])=C1OC([H])([H])[H])C1=C([H])N(C([H])=N1)C1=NC(=NC(=N1)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]OC1=C(OC([H])([H])[H])C([H])=C(\C([H])=N\N([H])C2=NC(=NC(=N2)N2C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])N2C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])C([H])=C1OC([H])([H])[H]
[H]OC1=C([H])C([H])=C([H])C([H])=C1C1=NC2=C(N=C([H])N2[H])C(=N1)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]N1C([H])=NC2=C1N=C(N=C2N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C1=C([H])C([H])=C([H])S1
[H]OC1=C([H])C([H])=C([H])C(=C1[H])C1=NC2=C(N=C([H])N2C([H])([H])C2([H])C([H])([H])C([H])([H])N(C([H])([H])C3=C([H])C([H])=C([H])C([H])=C3[H])C([H])([H])C2([H])[H])C(=N1)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]OC([H])([H])C1=C([H])C([H])=C([H])C(=C1[H])C1=NC2=C(C([H])=NN2C2([H])C([H])([H])C([H])([H])N(C([H])([H])C3=C([H])C([H])=C([H])C([H])=C3[H])C([H])([H])C2([H])[H])C(=N1)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]OC1=C([H])C(O[H])=C2C(=O)\C(OC2=C1[H])=C(/[H])C1=C([H])N([H])C2=C1C([H])=C(OC([H])([H])[H])C([H])=C2[H]
[H]OC1=C([H])C(O[H])=C2C(=O)\C(OC2=C1[H])=C(/[H])C1=C([H])N([H])C2=C1C([H])=C(Br)C([H])=C2[H]
[H]OC1=C([H])C(O[H])=C2C(=O)\C(OC2=C1[H])=C(/[H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H]
[H]OC1=C([H])C(O[H])=C2C(O\C(=C(\[H])C3=C(N(C4=C3C([H])=C(OC([H])([H])[H])C([H])=C4[H])C([H])([H])C([H])([H])C([H])([H])N3C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])O[H])C([H])([H])C3([H])[H])C([H])([H])[H])C2=O)=C1[H]
[H]OC1=C([H])C(O[H])=C2C(O\C(=C(\[H])C3=C(N(C4=C3C([H])=C(OC([H])([H])[H])C([H])=C4[H])C([H])([H])C([H])([H])C([H])([H])N3C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C3([H])[H])C([H])([H])[H])C2=O)=C1[H]
[H]OC1=C([H])C(O[H])=C2C(O\C(=C(\[H])C3=C(N(C4=C3C([H])=C(OC([H])([H])[H])C([H])=C4[H])C([H])([H])C([H])([H])C([H])([H])N3C([H])([H])C([H])([H])OC([H])([H])C3([H])[H])C([H])([H])[H])C2=O)=C1[H]
[H]OC1=C([H])C(O[H])=C2C(O\C(=C(\[H])C3=C(N(C4=C3C([H])=C(OC([H])([H])[H])C([H])=C4[H])C([H])([H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C2=O)=C1[H]
[H]OC1=C([H])C(O[H])=C2C(O\C(=C(\[H])C3=C([H])N(C4=C3C([H])=C(OC([H])([H])[H])C([H])=C4[H])C([H])([H])C([H])([H])C([H])([H])N3C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])O[H])C([H])([H])C3([H])[H])C2=O)=C1[H]
[H]OC1=C([H])C(O[H])=C2C(=O)\C(OC2=C1[H])=C(/[H])C1=C([H])N(C2=C1C([H])=C(OC([H])([H])[H])C([H])=C2[H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]OC1=C([H])C(O[H])=C2C(O\C(=C(\[H])C3=C([H])N(C4=C3C([H])=C(OC([H])([H])[H])C([H])=C4[H])C([H])([H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H])C2=O)=C1[H]
[H]OC1=C([H])C(O[H])=C2C(O\C(=C(\[H])C3=C(N(C4=C3C([H])=C(OC([H])([H])[H])C([H])=C4[H])C([H])([H])C([H])([H])N3C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])O[H])C([H])([H])C3([H])[H])C([H])([H])[H])C2=O)=C1[H]
[H]OC1=C([H])C(O[H])=C2C(O\C(=C(\[H])C3=C(N(C4=C3C([H])=C(OC([H])([H])[H])C([H])=C4[H])C([H])([H])C([H])([H])N3C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C3([H])[H])C([H])([H])[H])C2=O)=C1[H]
[H]OC1=C([H])C(O[H])=C2C(O\C(=C(\[H])C3=C(N(C4=C3C([H])=C(OC([H])([H])[H])C([H])=C4[H])C([H])([H])C([H])([H])N3C([H])([H])C([H])([H])OC([H])([H])C3([H])[H])C([H])([H])[H])C2=O)=C1[H]
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[H]N(C(=O)N([H])C1=C([H])C2=C(O\C(=C(\[H])C3=C([H])N(C4=NC([H])=C([H])C(N5C([H])([H])C([H])([H])C([H])(C(=O)N6[C@@]7([H])C([H])([H])C([H])([H])[C@]6([H])C([H])([H])OC7([H])[H])C([H])([H])C5([H])[H])=C34)C([H])([H])[H])C2=O)C([H])=C1[H])C1=C([H])N=C([H])C([H])=C1[H]
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[H]N(C(=O)N([H])C1=C([H])C2=C(O\C(=C(\[H])C3=C([H])N(C4=NC([H])=C([H])C(N5[C@@]6([H])C([H])([H])C([H])([H])[C@]5([H])C([H])([H])OC6([H])[H])=C34)C([H])([H])[H])C2=O)C([H])=C1[H])C1=C([H])N=C([H])C([H])=C1[H]
[H]N(C(=O)N([H])C1=C([H])C2=C(O\C(=C(\[H])C3=C([H])N(C4=NC([H])=C([H])C(N5C([H])([H])[C@@]6([H])OC([H])([H])[C@]5([H])C([H])([H])C6([H])[H])=C34)C([H])([H])[H])C2=O)C([H])=C1[H])C1=C([H])N=C([H])C([H])=C1[H]
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[H]N(C(=O)N([H])C1=C([H])C2=C(O\C(=C(\[H])C3=C([H])N(C4=NC([H])=C([H])C(N5C([H])([H])C([H])([H])C([H])(C(=O)N6C([H])([H])C([H])([H])[C@]([H])(N(C([H])([H])[H])C([H])([H])[H])C6([H])[H])C([H])([H])C5([H])[H])=C34)C([H])([H])[H])C2=O)C([H])=C1[H])C1=C([H])N=C([H])C([H])=C1[H]
[H]N(C(=O)N([H])C1=C([H])C2=C(O\C(=C(\[H])C3=C([H])N(C4=NC([H])=C([H])C(N5C([H])([H])C([H])([H])C([H])(C(=O)N6C([H])([H])C([H])([H])[C@@]([H])(OC([H])([H])[H])C6([H])[H])C([H])([H])C5([H])[H])=C34)C([H])([H])[H])C2=O)C([H])=C1[H])C1=C([H])N=C([H])C([H])=C1[H]
[H]N(C(=O)N([H])C1=C([H])C2=C(O\C(=C(\[H])C3=C([H])N(C4=NC([H])=C([H])C(N5C([H])([H])C([H])([H])C([H])(C(=O)N6C([H])([H])C([H])([H])C([H])([H])C([H])([H])C6([H])[H])C([H])([H])C5([H])[H])=C34)C([H])([H])[H])C2=O)C([H])=C1[H])C1=C([H])N=C([H])C([H])=C1[H]
[H]N(C(=O)N([H])C1=C([H])C2=C(O\C(=C(\[H])C3=C([H])N(C4=NC([H])=C([H])C(N5C([H])([H])C([H])([H])C([H])(C(=O)N6C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C6([H])[H])C([H])([H])C5([H])[H])=C34)C([H])([H])[H])C2=O)C([H])=C1[H])C1=C([H])N=C([H])C([H])=C1[H]
[H]OC1=C([H])C([H])=C([H])C2=C1C(=O)\C(O2)=C(/[H])C1=C([H])N(C2=C1C(=C([H])C([H])=N2)C1=C([H])C([H])=C([H])C([H])=C1C(=O)N(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H]
[H]OC1=C([H])C([H])=C([H])C2=C1C(=O)\C(O2)=C(/[H])C1=C([H])N(C2=C1C(=C([H])C([H])=N2)N1C([H])([H])C([H])([H])C([H])(C(=O)N([H])[H])C([H])([H])C1([H])[H])C([H])([H])[H]
[H]OC1=C([H])C([H])=C([H])C2=C1C(=O)\C(O2)=C(/[H])C1=C([H])N(C2=C1C(=C([H])C([H])=N2)N1C([H])([H])C([H])([H])C([H])(C([H])([H])N([H])[H])C([H])([H])C1([H])[H])C([H])([H])[H]
[H]OC1=C([H])C([H])=C([H])C2=C1C(=O)\C(O2)=C(/[H])C1=C([H])N(C2=C1C(=C([H])C([H])=N2)N1C([H])([H])C([H])([H])C([H])(N([H])[H])C([H])([H])C1([H])[H])C([H])([H])[H]
[H]OC1=C([H])C([H])=C([H])C2=C1C(=O)\C(O2)=C(/[H])C1=C([H])N(C2=C1C(=C([H])C([H])=N2)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C([H])([H])[H]
[H]OC1=C([H])C([H])=C([H])C2=C1C(=O)\C(O2)=C(/[H])C1=C([H])N(C2=C1C(=C([H])C([H])=N2)N1C([H])([H])[C@@]2([H])O[C@]([H])(C([H])([H])C2([H])[H])C1([H])[H])C([H])([H])[H]
[H]OC1=C([H])C([H])=C([H])C2=C1C(=O)\C(O2)=C(/[H])C1=C([H])N(C2=C1C(=C([H])C([H])=N2)N1[C@@]2([H])C([H])([H])C([H])([H])[C@]1([H])C([H])([H])OC2([H])[H])C([H])([H])[H]
[H]OC1=C([H])C([H])=C([H])C2=C1C(=O)\C(O2)=C(/[H])C1=C([H])N(C2=C1C(=C([H])C([H])=N2)N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H])C([H])([H])[H]
[H]OC1=C([H])C2=C(C(=O)\C(O2)=C(/[H])C2=C([H])N(C3=C2C(=C([H])C([H])=N3)N2C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C2([H])[H])C([H])([H])[H])C(O[H])=C1[H]
[H]N(C(=O)N([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC2=C(C([H])=C([H])N2C([H])([H])C([H])([H])[H])C(=N1)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C(=O)N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H]
[H]N(C(=O)N([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC2=C(C([H])=C([H])N2C([H])([H])C([H])([H])[H])C(=N1)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C(=O)N1C([H])([H])C([H])([H])N([H])C([H])([H])C1([H])[H]
[H]OC1=C([H])C(O[H])=C2C(=O)\C(OC2=C1[H])=C(/[H])C1=C(N([H])C2=C1C([H])=C([H])C([H])=C2[H])C([H])([H])[H]
[H]OC1=C([H])C(O[H])=C2C(=O)\C(OC2=C1[H])=C(/[H])C1=C([H])N([H])C2=C1C([H])=C(OC1=C([H])C([H])=C([H])C([H])=C1[H])C([H])=C2[H]
[H]OC([H])([H])C1=C([H])C(=C([H])C([H])=C1[H])C1=NC2=C(N([H])C([H])=C2[H])C(=N1)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]N1C([H])=C([H])C2=C1C(=NC(=N2)C1=C([H])C([H])=C([H])C(=C1[H])C([H])([H])[H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]OC1=C([H])C(=C([H])C([H])=C1[H])C1=NC2=C(N([H])C([H])=C2[H])C(=N1)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]N([H])C1=C([H])C(=C([H])C([H])=C1[H])C1=NC2=C(N([H])C([H])=C2[H])C(=N1)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]OC([H])([H])C1=C([H])C(=C([H])C([H])=C1[H])C1=NC2=C(N([H])C([H])=C2C([H])([H])N(C([H])([H])[H])C([H])([H])[H])C(=N1)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]OC([H])([H])C1=C([H])C(=C([H])C([H])=C1[H])C1=NC2=C(N([H])C([H])=C2C([H])([H])N2C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C(=N1)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]OC([H])([H])C1=C([H])C(=C([H])C([H])=C1[H])C1=NC2=C(N(C([H])=C2[H])C([H])([H])[H])C(=N1)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]N(C(=O)N([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC2=C(C([H])=C([H])N2C([H])([H])C([H])(OC([H])([H])[H])OC([H])([H])[H])C(=N1)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C1=C([H])C([H])=NC([H])=C1[H]
[H]N(C(=O)N([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC2=C(C([H])=C([H])N2C([H])([H])C([H])=O)C(=N1)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C1=C([H])C([H])=NC([H])=C1[H]
[H]N(C(=O)N([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC2=C(C([H])=C([H])N2C([H])([H])C([H])([H])N2C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C(=N1)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C1=C([H])C([H])=NC([H])=C1[H]
[H]N(C(=O)N([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC2=C(C([H])=C([H])N2C([H])([H])C([H])([H])N2C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C(=N1)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C1=C([H])C([H])=NC([H])=C1[H]
[H]N(C(=O)N([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC2=C(C([H])=C([H])N2C([H])([H])C([H])([H])N([H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H])C(=N1)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C1=C([H])C([H])=NC([H])=C1[H]
[H]N(C(=O)N([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC2=C(C([H])=C([H])N2C([H])([H])C([H])([H])N2C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C2([H])[H])C(=N1)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C1=C([H])C([H])=NC([H])=C1[H]
[H]N(C(=O)N([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC2=C(C([H])=C([H])N2C([H])([H])C([H])([H])N2C([H])([H])C([H])([H])N([H])C([H])([H])C2([H])[H])C(=N1)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C1=C([H])C([H])=NC([H])=C1[H]
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[H]OC([H])([H])C1=C(OC([H])([H])[H])C([H])=C([H])C(=C1[H])C1=C([H])C([H])=C2C(N=C(N=C2N2C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])N2C([H])([H])[C@@]([H])(O[C@]([H])(C([H])([H])[H])C2([H])[H])C([H])([H])[H])=N1
[H]OC(C1=C([H])C2=C(S1)C(=NC(=N2)C1=C(N=C(N=C1[H])N([H])[H])C([H])([H])[H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]OC(C1=C([H])C2=C(S1)C(=NC(=N2)C1=C2C([H])=NN([H])C2=C([H])C([H])=C1[H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]OC(C1=C([H])C2=C(S1)C(=NC(=N2)C1=C([H])N=C(N=C1[H])N([H])[H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]N([H])C1=NC(=C(C([H])=N1)C1=NC2=C(SC(=C2[H])C([H])([H])N2C([H])([H])C([H])([H])N(C([H])([H])C2([H])[H])S(=O)(=O)C([H])([H])[H])C(=N1)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C([H])([H])[H]
[H]N(C(=O)N([H])C([H])([H])C([H])([H])[H])C1=C([H])C2=C(O\C(=C(\[H])C3=C([H])N(C4=NC([H])=C([H])C(N5C([H])([H])[C@@]6([H])O[C@]([H])(C([H])([H])C6([H])[H])C5([H])[H])=C34)C([H])([H])[H])C2=O)C([H])=C1[H]
[H]N(C(=O)N([H])C([H])([H])[H])C1=C([H])C2=C(O\C(=C(\[H])C3=C([H])N(C4=NC([H])=C([H])C(N5C([H])([H])[C@@]6([H])O[C@]([H])(C([H])([H])C6([H])[H])C5([H])[H])=C34)C([H])([H])[H])C2=O)C([H])=C1[H]
[H]N(C(=O)N([H])C([H])([H])[H])C1=C([H])C([H])=C([H])C2=C1C(=O)\C(O2)=C(/[H])C1=C([H])N(C2=NC([H])=C([H])C(=C12)C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H]
[H]N(C(=O)N([H])C([H])([H])[H])C1=C([H])C2=C(O\C(=C(\[H])C3=C([H])N(C4=NC([H])=C([H])C(=C34)C3=C([H])C([H])=C([H])C([H])=C3[H])C([H])([H])[H])C2=O)C([H])=C1[H]
[H]OC1=C([H])C([H])=C([H])C2=C1C(=O)\C(O2)=C(/[H])C1=C([H])N(C2=NC([H])=C([H])C(=C12)C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H]
[H]OC1=C([H])C([H])=C([H])C2=C1C(=O)\C(O2)=C(/[H])C1=C([H])N(C2=C1C(=C([H])C([H])=N2)C1=C([H])C([H])=C(C([H])=C1[H])C(=O)N1C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])O[H])C([H])([H])C1([H])[H])C([H])([H])C([H])([H])[H]
[H]OC1=C([H])C([H])=C([H])C2=C1C(=O)\C(O2)=C(/[H])C1=C([H])N(C2=C1C(=C([H])C([H])=N2)C1=C([H])C([H])=C([H])C(=C1[H])C(=O)N(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H]
[H]OC1=C([H])C(O[H])=C2C(O\C(=C(\[H])C3=C(N(C4=C3C([H])=C(OC([H])([H])[H])C([H])=C4[H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C2=O)=C1[H]
[H]OC1=C([H])C(O[H])=C2C(O\C(=C(\[H])C3=C([H])N(C4=C3C([H])=C(OC([H])([H])[H])C([H])=C4[H])C([H])([H])C([H])([H])N3C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])C([H])([H])O[H])C([H])([H])C3([H])[H])C2=O)=C1[H]
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[H]N(C(=O)N([H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H])C1=C([H])C2=C(O\C(=C(\[H])C3=C([H])N(C4=NC([H])=C([H])C(N5C([H])([H])[C@@]6([H])O[C@]([H])(C([H])([H])C6([H])[H])C5([H])[H])=C34)C([H])([H])[H])C2=O)C([H])=C1[H]
[H]N(C(=O)N([H])C1=C([H])C2=C(O\C(=C(\[H])C3=C([H])N(C4=NC([H])=C([H])C(N5C([H])([H])C([H])([H])C([H])(C(=O)N(C6=C([H])C([H])=C([H])N=C6[H])C([H])([H])[H])C([H])([H])C5([H])[H])=C34)C([H])([H])[H])C2=O)C([H])=C1[H])C1=C([H])N=C([H])C([H])=C1[H]
[H]N(C(=O)N([H])C1=C([H])C2=C(O\C(=C(\[H])C3=C([H])N(C4=NC([H])=C([H])C(N5C([H])([H])C([H])([H])C([H])(C(=O)N(C([H])([H])[H])C([H])([H])C6=C([H])C([H])=C([H])C([H])=C6[H])C([H])([H])C5([H])[H])=C34)C([H])([H])[H])C2=O)C([H])=C1[H])C1=C([H])N=C([H])C([H])=C1[H]
[H]N(C(=O)N([H])C1=C([H])C2=C(O\C(=C(\[H])C3=C([H])N(C4=NC([H])=C([H])C(N5C([H])([H])C([H])([H])C([H])(C(=O)N(C([H])([H])[H])C([H])([H])C6=C([H])C([H])=C([H])C([H])=N6)C([H])([H])C5([H])[H])=C34)C([H])([H])[H])C2=O)C([H])=C1[H])C1=C([H])N=C([H])C([H])=C1[H]
[H]N(C(=O)N([H])C1=C([H])C2=C(O\C(=C(\[H])C3=C([H])N(C4=NC([H])=C([H])C(N5C([H])([H])C([H])([H])C([H])(C(=O)N(C([H])([H])[H])C([H])([H])C6=C([H])C([H])=NC([H])=C6[H])C([H])([H])C5([H])[H])=C34)C([H])([H])[H])C2=O)C([H])=C1[H])C1=C([H])N=C([H])C([H])=C1[H]
[H]N(C(=O)N([H])C1=C([H])C2=C(O\C(=C(\[H])C3=C([H])N(C4=NC([H])=C([H])C(N5C([H])([H])C([H])([H])C([H])(C(=O)N(C([H])([H])[H])C([H])([H])C6=C([H])N=C([H])C([H])=C6[H])C([H])([H])C5([H])[H])=C34)C([H])([H])[H])C2=O)C([H])=C1[H])C1=C([H])N=C([H])C([H])=C1[H]
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[H]N([H])C1=C([H])C([H])=C(C#CC2=NN([H])C3=C([H])C([H])=C([H])C([H])=C23)C([H])=C1[H]
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[H]N([H])C1=NC(=NC2=C(C([H])=C(C([H])=C12)C([H])([H])[H])C(=O)N([H])C1=C([H])N=C(OC([H])([H])[H])C([H])=C1[H])C([H])([H])[H]
[H]N([H])C1=NC(=NC2=C(C(=O)N([H])C3=C([H])C([H])=NN3[H])C(=C([H])C([H])=C12)C([H])([H])[H])C([H])([H])[H]
[H]N([H])C1=NC(=NC2=C(C([H])=C(C([H])=C12)C([H])([H])[H])C(=O)N([H])C1=C([H])C([H])=NN1[H])C([H])([H])[H]
[H]N([H])C1=NC(=NC2=C(C([H])=C(C([H])=C12)C([H])([H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C(=O)N([H])C1=C([H])C([H])=NN1[H])C([H])([H])[H]
[H]N([H])C1=NC(=NC2=C(C([H])=C(C([H])=C12)C([H])([H])N(C([H])([H])[H])C([H])([H])[H])C(=O)N([H])C1=C([H])C([H])=NN1[H])C([H])([H])[H]
[H]N([H])C1=NC(=NC2=C(C([H])=C([H])C([H])=C12)C(=O)N([H])C1=C([H])N=C(C([H])=C1[H])C([H])([H])[H])C([H])([H])[H]
[H]N([H])C1=NC(=NC2=C(C(=O)N([H])C3=C([H])N=C(C([H])=C3[H])C([H])([H])[H])C(=C([H])C([H])=C12)C([H])([H])[H])C([H])([H])[H]
[H]N([H])C1=NC(=NC2=C(C([H])=C(C([H])=C12)C([H])([H])[H])C(=O)N([H])C1=C([H])N=C(C([H])=C1[H])C([H])([H])[H])C([H])([H])[H]
[H]N([H])C1=NC(=NC2=C(C([H])=C([H])C([H])=C12)C(=O)N([H])C1=C([H])N=C(C([H])=C1[H])N(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H]
[H]N([H])C1=NC(=NC2=C(C([H])=C(C([H])=C12)C([H])([H])[H])C(=O)N([H])C1=C([H])N=C(C([H])=C1[H])N(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H]
[H]N([H])C1=NC(=NC2=C(C([H])=C([H])C([H])=C12)C(=O)N([H])C1=C([H])N=C2N([H])C([H])=C([H])C2=C1[H])C([H])([H])[H]
[H]N([H])C1=NC(=NC2=C(C(=O)N([H])C3=C([H])N=C4N([H])C([H])=C([H])C4=C3[H])C(=C([H])C([H])=C12)C([H])([H])[H])C([H])([H])[H]
[H]N([H])C1=NC(=NC2=C(C([H])=C(C([H])=C12)C([H])([H])[H])C(=O)N([H])C1=C([H])N=C2N([H])C([H])=C([H])C2=C1[H])C([H])([H])[H]
[H]N([H])C1=NC(=NC2=C(C([H])=C([H])C([H])=C12)C(=O)N([H])C1=C([H])N([H])N=C1[H])C([H])([H])[H]
[H]N([H])C1=NC(=NC2=C(C([H])=C(C([H])=C12)C([H])([H])[H])C(=O)N([H])C1=C([H])N([H])N=C1[H])C([H])([H])[H]
[H]N([H])C1=NC([H])=C(C([H])=N1)C1=C([H])C(=NC(=N1)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])N([H])C1=C([H])C([H])=C(OC([H])([H])[H])N=C1[H]
[H]N([H])C1=NC(=NC2=C(C(=O)N([H])C3=C([H])N=C(OC([H])([H])[H])C([H])=C3[H])C(=C([H])C([H])=C12)C([H])([H])[H])C([H])([H])[H]
[H]N([H])C1=NC([H])=C(C([H])=N1)C1=C2C(=NC(=N1)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])N(C([H])([H])C2([H])[H])S(=O)(=O)C([H])([H])[H]
[H]OC([H])([H])C(C(=O)O[C@]1([H])C([H])([H])C([H])([H])[C@@]([H])(C([H])([H])[C@@]([H])(C([H])([H])[H])[C@@]2([H])OC(=O)[C@@]3([H])N(C(=O)C(=O)[C@]4(O[H])O[C@@]([H])(C([H])([H])C([H])([H])[C@@]4([H])C([H])([H])[H])C([H])([H])[C@]([H])(OC([H])([H])[H])\C(=C(/[H])\C(\[H])=C(/[H])\C(\[H])=C([H])\[C@@]([H])(C([H])([H])[H])C([H])([H])[C@]([H])(C(=O)[C@]([H])(OC([H])([H])[H])[C@]([H])(O[H])\C(=C([H])\[C@]([H])(C(=O)C2([H])[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C3([H])[H])C([H])([H])[C@@]1([H])OC([H])([H])[H])(C([H])([H])[H])C([H])([H])O[H]
[H]N([H])C1=C(N([H])C(=O)C2=C([H])C(N([H])C(=O)N([H])C3=C([H])C([H])=C(Cl)C(=C3[H])C(F)(F)F)=C([H])C([H])=C2C([H])([H])[H])C([H])=NN1C([H])([H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]N(C1=C([H])N=C([H])C(=C1[H])C1=C([H])N2C(=NC([H])=C2C2=NOC(=N2)C([H])([H])[H])C([H])=C1[H])S(=O)(=O)C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)C([H])([H])[H])C1=NC2=C([H])C([H])=C(C([H])=C2S1)C1=C([H])C([H])=NC(SC2=C([H])C([H])=C([H])C([H])=C2[H])=N1
[H]N(C(=O)C([H])([H])[H])C1=NC2=C([H])C([H])=C(C([H])=C2S1)C1=C([H])C([H])=NC(SC([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])=N1
[H]N(C(=O)C([H])([H])[H])C1=NC2=C([H])C([H])=C(C([H])=C2S1)C1=C([H])C([H])=NC(OC2=C([H])C([H])=C([H])C([H])=C2[H])=N1
[H]N(C(=O)C([H])([H])[H])C1=NC2=C([H])C([H])=C(C([H])=C2S1)C1=C([H])C([H])=NC(OC([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])=N1
[H]N(C(=O)C([H])([H])[H])C1=NC2=C([H])C([H])=C(C([H])=C2S1)C1=C([H])C([H])=NC(=N1)N([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)C([H])([H])[H])C1=NC2=C([H])C([H])=C(C([H])=C2S1)C1=C([H])C([H])=NC(=N1)N([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)C([H])([H])[H])C1=NC2=C([H])C([H])=C(C([H])=C2S1)C1=C([H])C([H])=NC(=N1)C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)C([H])([H])[H])C1=NC2=C([H])C([H])=C(C([H])=C2S1)C1=C([H])C([H])=NC(=N1)C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N(C(=O)C([H])([H])[H])C1=NC2=C([H])C([H])=C(C([H])=C2S1)C1=C([H])C([H])=NC(SC2=C([H])C([H])=C([H])C([H])=C2F)=N1
[H]N(C(=O)C([H])([H])[H])C1=NC2=C([H])C([H])=C(C([H])=C2S1)C1=C([H])C([H])=NC(SC2=C([H])C([H])=C([H])C(F)=C2[H])=N1
[H]N(C(=O)C([H])([H])[H])C1=NC2=C([H])C([H])=C(C([H])=C2S1)C1=C([H])C([H])=NC(SC2=C([H])C([H])=C(F)C([H])=C2[H])=N1
[H]N(C(=O)C([H])([H])[H])C1=NC2=C([H])C([H])=C(C([H])=C2S1)C1=C([H])C([H])=NC(SC2=C([H])C([H])=C([H])C([H])=C2C([H])([H])[H])=N1
[H]N(C(=O)C([H])([H])[H])C1=NC2=C([H])C([H])=C(C([H])=C2S1)C1=C([H])C([H])=NC(SC2=C([H])C([H])=C([H])C(=C2[H])C([H])([H])[H])=N1
[H]N(C(=O)C([H])([H])[H])C1=NC2=C([H])C([H])=C(C([H])=C2S1)C1=C([H])C([H])=NC(SC2=C([H])C([H])=C(C([H])=C2[H])C([H])([H])[H])=N1
[H]N(C(=O)C([H])([H])[H])C1=NC2=C([H])C([H])=C(C([H])=C2S1)C1=C([H])C([H])=NC(SC2=C([H])C([H])=C([H])C([H])=C2OC([H])([H])[H])=N1
[H]N(C(=O)C([H])([H])[H])C1=NC2=C([H])C([H])=C(C([H])=C2S1)C1=C([H])C([H])=NC(SC2=C([H])C([H])=C([H])C(OC([H])([H])[H])=C2[H])=N1
[H]N(C(=O)C([H])([H])[H])C1=NC2=C([H])C([H])=C(C([H])=C2S1)C1=C([H])C([H])=NC(SC2=C([H])C([H])=C(OC([H])([H])[H])C([H])=C2[H])=N1
[H]N(C(=O)C([H])([H])[H])C1=NC2=C([H])C([H])=C(C([H])=C2S1)C1=C([H])C([H])=NC(OC([H])([H])C2=C([H])C(F)=C([H])C([H])=C2[H])=N1
[H]N(C(=O)C([H])([H])[H])C1=NC2=C([H])C([H])=C(C([H])=C2S1)C1=C([H])C([H])=NC(OC([H])([H])C2=C([H])C(=C([H])C([H])=C2[H])C([H])([H])[H])=N1
[H]N(C(=O)C([H])([H])[H])C1=NC2=C([H])C([H])=C(C([H])=C2S1)C1=C([H])C([H])=NC(OC([H])([H])C2=C([H])C(OC([H])([H])[H])=C([H])C([H])=C2[H])=N1
[H]N(C(=O)C([H])([H])[H])C1=NC2=C([H])C([H])=C(C([H])=C2S1)C1=C([H])C([H])=NC(OC([H])([H])C2=C([H])C([H])=C(F)C([H])=C2[H])=N1
[H]N(C(=O)C([H])([H])[H])C1=NC2=C([H])C([H])=C(C([H])=C2S1)C1=C([H])C([H])=NC(OC([H])([H])C2=C([H])C([H])=C(C([H])=C2[H])C([H])([H])[H])=N1
[H]N(C(=O)C([H])([H])[H])C1=NC2=C([H])C([H])=C(C([H])=C2S1)C1=C([H])C([H])=NC(OC([H])([H])C2=C([H])C([H])=C(OC([H])([H])[H])C([H])=C2[H])=N1
[H]N(C(=O)C([H])([H])[H])C1=NC2=C([H])C([H])=C(C([H])=C2S1)C1=C([H])C([H])=NC(OC([H])([H])C2=C([H])C([H])=NC([H])=C2[H])=N1
[H]N(C(=O)C([H])([H])[H])C1=NC2=C([H])C([H])=C(C([H])=C2S1)C1=C([H])C([H])=NC(OC([H])([H])C([H])([H])C([H])([H])C2=C([H])C([H])=NC([H])=C2[H])=N1
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[H]N(C(=O)C([H])([H])[H])C1=NC2=C([H])C([H])=C(C([H])=C2S1)C1=C([H])C([H])=NC(OC([H])([H])C([H])([H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])=N1
[H]N(C(=O)C([H])([H])[H])C1=NC2=C([H])C([H])=C(C([H])=C2S1)C1=C([H])C([H])=NC(OC([H])([H])C([H])([H])C([H])([H])N2C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])=N1
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[H]N(C(=O)C([H])([H])[H])C1=NC2=C([H])C([H])=C(C([H])=C2S1)C1=C([H])C([H])=NC(=N1)N(C([H])([H])[H])S(=O)(=O)C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
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[H]N(C(=O)C([H])([H])[H])C1=NC2=C([H])C([H])=C(C([H])=C2S1)C1=C([H])C([H])=NC(=N1)N([H])S(=O)(=O)C1=C([H])C([H])=C([H])C([H])=C1F
[H]N(C(=O)C([H])([H])[H])C1=NC2=C([H])C([H])=C(C([H])=C2S1)C1=C([H])C([H])=NC(=N1)N(C([H])([H])[H])S(=O)(=O)C1=C([H])C([H])=C([H])C([H])=C1F
[H]N(C(=O)C([H])([H])[H])C1=NC2=C([H])C([H])=C(C([H])=C2S1)C1=C([H])C([H])=NC(=N1)N([H])S(=O)(=O)C1=C([H])C([H])=C([H])C(F)=C1[H]
[H]N(C(=O)C([H])([H])[H])C1=NC2=C([H])C([H])=C(C([H])=C2S1)C1=C([H])C([H])=NC(=N1)N([H])S(=O)(=O)C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]N(C(=O)C([H])([H])[H])C1=NC2=C([H])C([H])=C(C([H])=C2S1)C1=C([H])C([H])=NC(=N1)N([H])S(=O)(=O)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H]
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[H]N([H])C1=NC2=C(O1)C([H])=C(C([H])=C2[H])C1=C([H])N=C(Cl)C(N([H])S(=O)(=O)C2=C([H])C([H])=C(F)C([H])=C2[H])=C1[H]
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[H]N(C(=O)N([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC(OC([H])(C([H])([H])[H])C([H])([H])[H])=NC(=N1)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C(=O)N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H]
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[H]N(C(=O)N([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC(=O)N=C(N1[H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C(=O)N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H]
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[H]OC1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])N=C2N([H])C(=O)N(C2=N1)C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1OC([H])([H])[H]
[H]OC1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])N=C2N([H])C(=O)N(C2=N1)C([H])([H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
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[H]OC1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])N=C2N([H])C(=O)N(C2=N1)C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])N=C2N([H])C(=O)N(C2=N1)C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]OC1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])N=C2N([H])C(=O)N(C2=N1)C([H])([H])C([H])([H])OC([H])([H])[H]
[H]OC1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])N=C2N([H])C(=O)N(C2=N1)C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]OC1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])N=C2N([H])C(=O)N(C2=N1)C([H])([H])C1([H])C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]OC1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])N=C2N([H])C(=O)N(C2=N1)C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]OC1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])N=C2N([H])C(=O)N(C2=N1)C1([H])C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]OC1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])N=C2N([H])C(=O)N(C2=N1)[C@@]1([H])C([H])([H])C([H])([H])[C@@]([H])(C(=O)N([H])[H])C([H])([H])C1([H])[H]
[H]OC([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])N=C2N([H])C(=O)N(C2=N1)C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]OC(=O)C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])N=C2N([H])C(=O)N(C2=N1)C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N([H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])N=C2N([H])C(=O)N(C2=N1)C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N([H])C(=O)C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])N=C2N([H])C(=O)N(C2=N1)C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])N=C2N([H])C(=O)N(C2=N1)C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])[H]
[H]N(C(=O)C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])N=C2N([H])C(=O)N(C2=N1)C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]OC(C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])N=C2N([H])C(=O)N(C2=N1)C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])(C([H])([H])[H])C([H])([H])[H]
[H]N1N=C(N=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])N=C2N([H])C(=O)N(C2=N1)C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N1C([H])=C([H])N=C1C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])N=C2N([H])C(=O)N(C2=N1)C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N1C([H])=C([H])N=C1C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])N=C2N([H])C(=O)N(C2=N1)C([H])([H])C1([H])C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]N1C([H])=NC([H])=C1C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])N=C2N([H])C(=O)N(C2=N1)C([H])([H])C1([H])C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]N1C(=O)N(C2=NC(=C([H])N=C12)C1=C([H])C([H])=C(C([H])=C1[H])N1C([H])=NC([H])=C1[H])C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N1C(=O)N(C2=NC(=C([H])N=C12)C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])N=C([H])O1)C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N1N=C([H])C([H])=C1C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])N=C2N([H])C(=O)N(C2=N1)C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N1N=C([H])C(=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])N=C2N([H])C(=O)N(C2=N1)C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N1C(=O)N(C2=NC(=C([H])N=C12)C1=C([H])C([H])=C(C([H])=C1[H])N1N=C([H])C([H])=C1[H])C([H])([H])C1([H])C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]N1N=C([H])C2=C1C([H])=C([H])C(=C2[H])C1=C([H])N=C2N([H])C(=O)N(C2=N1)C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N1C([H])=NC2=C1N=C([H])C(=C2[H])C1=C([H])N=C2N([H])C(=O)N(C2=N1)C([H])([H])C1([H])C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]N1C([H])=NC2=C1C([H])=C([H])C(=C2[H])C1=C([H])N=C2N([H])C(=O)N(C2=N1)C([H])([H])C1([H])C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]N1C([H])=NC2=C1C([H])=C([H])C(=C2[H])C1=C([H])N=C2N([H])C(=O)N(C2=N1)C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N([H])C1=NC2=C(N1[H])C([H])=C([H])C(=C2[H])C1=C([H])N=C2N([H])C(=O)N(C2=N1)C([H])([H])C1([H])C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]N([H])C1=NC2=C(N1[H])C([H])=C([H])C(=C2[H])C1=C([H])N=C2N([H])C(=O)N(C2=N1)C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(C1=NC2=C(N1[H])C([H])=C([H])C(=C2[H])C1=C([H])N=C2N([H])C(=O)N(C2=N1)C([H])([H])C1([H])C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C([H])([H])[H]
[H]N1C([H])=C([H])C2=C1C([H])=C([H])C(=C2[H])C1=C([H])N=C2N([H])C(=O)N(C2=N1)C([H])([H])C1([H])C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]N1C([H])=C([H])C2=C1C([H])=C([H])C(=C2[H])C1=C([H])N=C2N([H])C(=O)N(C2=N1)C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N1C([H])=C([H])C2=C1C([H])=C(C([H])=C2[H])C1=C([H])N=C2N([H])C(=O)N(C2=N1)C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]C1=C([H])C2=C(C([H])=C1[H])N(C(=N2)C([H])(F)F)C1=NC(=NC(=N1)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]N(C1=NC(=NC(=N1)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])N1N=C([H])C([H])=C1[H])C1=C([H])C(Cl)=C([H])C([H])=C1[H]
[H]OC1=C([H])C(=C([H])C([H])=C1[H])C1=NC(=NC(=N1)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])N1C([H])=C([H])N=C1C([H])([H])[H]
[H]N([H])C1=NC([H])=C(C([H])=N1)C1=NC(=NC(=N1)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])N1C([H])=C([H])N=C1C([H])([H])[H]
[H]N1C([H])=C([H])C2=C1C([H])=C([H])C([H])=C2C1=NC(=NC(=N1)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])N1C([H])=C([H])N=C1C([H])([H])C([H])([H])[H]
[H]N1C([H])=C([H])C2=C1C([H])=C([H])C([H])=C2C1=NC(=NC(=N1)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])N1N=C(C([H])=C1C([H])([H])C([H])([H])[H])C(F)(F)F
[H]N1C([H])=C([H])C2=C1C(=C([H])C([H])=C2C1=NC(=NC(=N1)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])N1C([H])=C([H])N=C1C([H])([H])[H])C([H])([H])[H]
[H]OC1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])N=C2N([H])C(=O)N(C2=N1)C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N1N=NC(=N1)C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])N=C2N([H])C(=O)N(C2=N1)C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N1C(=O)C2=C(C3=C([H])C([H])=C(Cl)C(Cl)=C3N2C([H])([H])[H])[C@@]([H])(C#N)[C@@]11C([H])([H])C([H])([H])N([H])C([H])([H])C1([H])[H]
[H]OC1=C([H])C(=C([H])C([H])=C1[H])C1=NC2=C(N=C1C1=C([H])C([H])=C([H])C(O[H])=C1[H])C(=NC(=N2)N([H])[H])N([H])[H]
[H]OC([H])([H])C([H])([H])N(\N=C(/[H])C1=C2C([H])=C(C#N)C([H])=C([H])N2N=C1[H])S(=O)(=O)C1=C(C([H])=C([H])C(=C1[H])[N+]([O-])=O)C([H])([H])[H]
[H]N(C1=C([H])C(=C([H])N=C1Cl)C1=C([H])C([H])=C2N=C([H])C([H])=C(C3=C([H])C([H])=NC([H])=C3[H])C2=C1[H])S(=O)(=O)C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]N(C1=NC2=C([H])C(=C([H])C([H])=C2N=C1[H])C1=C([H])N=C(Cl)C(N([H])S(=O)(=O)C2=C([H])C([H])=C(F)C([H])=C2[H])=C1[H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]N(C1=C([H])C(=C([H])N=C1Cl)C1=C([H])C2=C(C([H])=C([H])N=C2C([H])=C1[H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])S(=O)(=O)C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]N(C1=C([H])C(=C([H])N=C1Cl)C1=C([H])C([H])=C2N=C([H])C(=NC2=C1[H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])S(=O)(=O)C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]N(C1=C([H])C(=C([H])N=C1Cl)C1=C([H])C([H])=C2N=C([H])C([H])=C(N3C([H])([H])C([H])([H])N(C([H])([H])C4=C([H])C([H])=NC([H])=C4[H])C([H])([H])C3([H])[H])C2=C1[H])S(=O)(=O)C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]N(C1=C([H])C(=C([H])N=C1Cl)C1=C([H])C([H])=C2N=C([H])C(=NC2=C1[H])N1C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])S(=O)(=O)C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]N(C1=C([H])C(=C([H])N=C1Cl)C1=C([H])C([H])=C2N=C([H])C([H])=C(C3=C([H])N=C([H])C([H])=C3[H])C2=C1[H])S(=O)(=O)C1=C([H])C([H])=C(F)C([H])=C1[H]
[H]N([H])C1=C2C(=NC([H])=N1)N(C([H])=C2C(=O)C1=NC(N([H])[C@]2([H])C([H])([H])C([H])([H])C([H])([H])[C@]2([H])C2=C([H])C([H])=C(F)C([H])=C2[H])=C([H])N=C1[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N([H])C1=C2C(=NC([H])=N1)N(C([H])=C2C(=O)C1=NC(N([H])[C@]2([H])C([H])([H])OC([H])([H])[C@]2([H])C2=C([H])C([H])=C(F)C([H])=C2[H])=C([H])N=C1[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N([H])C1=C2C(=NC([H])=N1)N(C([H])=C2C(=O)C1=NC(N([H])[C@]2([H])C([H])([H])C([H])([H])O[C@]2([H])C2=C([H])C([H])=C(F)C([H])=C2[H])=C([H])N=C1[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N([H])C1=C2C(=NC([H])=N1)N(C([H])=C2C(=O)C1=NC(N([H])[C@]2([H])C([H])([H])N([H])C([H])([H])[C@]2([H])C2=C([H])C([H])=C(F)C([H])=C2[H])=C([H])N=C1[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N([H])C1=C2C(=NC([H])=N1)N(C([H])=C2C(=O)C1=NC(N([H])[C@]2([H])C([H])([H])C([H])([H])N([H])[C@]2([H])C2=C([H])C([H])=C(F)C([H])=C2[H])=C([H])N=C1[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N([H])C1=C2C(=NC([H])=N1)N(C([H])=C2C(=O)C1=NC(N([H])[C@]2([H])C([H])([H])C([H])([H])N(C([H])=O)[C@]2([H])C2=C([H])C([H])=C(F)C([H])=C2[H])=C([H])N=C1[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N([H])C1=C2C(=NC([H])=N1)N(C([H])=C2C(=O)C1=NC(N([H])[C@]2([H])C([H])([H])C([H])([H])N(C(=O)C([H])([H])[H])[C@]2([H])C2=C([H])C([H])=C(F)C([H])=C2[H])=C([H])N=C1[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]N([H])C1=C2C(=NC([H])=N1)N(C([H])=C2C(=O)C1=NC(N([H])[C@]2([H])C([H])([H])C([H])([H])N(C(=O)C([H])([H])[H])[C@]2([H])C2=C([H])C([H])=C([H])C([H])=C2[H])=C([H])N=C1[H])C([H])(C([H])([H])[H])C([H])([H])[H]
[H]\C(=N/N(C([H])([H])[H])S(=O)(=O)C1=C(C([H])=C([H])C(=C1[H])[N+]([O-])=O)C([H])([H])[H])C1=C2C([H])=C(C#N)C([H])=C([H])N2N=C1[H]
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[H]N(C(=O)C([H])([H])[H])C1=C([H])C(=NC(=N1)C([H])([H])[H])C1=C(N=C2C([H])=C([H])C([H])=NN12)N([H])C1=NN([H])C([H])=C1[H]
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[H]N(C1=NN([H])C([H])=C1[H])C1=C(N2N=C([H])C([H])=C([H])C2=N1)C1=NC(=NC(N([H])C([H])([H])[H])=C1[H])C([H])([H])[H]
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[H]N1N=C(N=C1[H])C1=C(C(C#N)=C(S1)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]N1N=C([H])N=C1C1=C(C(C#N)=C(S1)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C1=C(Cl)C([H])=C(Cl)C([H])=C1[H]
[H]N1N=C([H])N=C1C1=C(C(C#N)=C(S1)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C1=C(F)C([H])=C(C#N)C([H])=C1[H]
[H]N([H])C1=NC([H])=C(C2=NC(=NC(=C2[H])N2C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])N2C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])C(=C1[H])C(F)(F)F
[H]N([H])C1=NC([H])=C(C([H])=N1)C1=NC2=C(SC(=C2C([H])([H])[H])C([H])([H])N2C([H])([H])C([H])([H])N(C(=O)C([H])([H])N([H])[H])C([H])([H])C2([H])[H])C(=N1)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]N([H])C1=NC([H])=C(C([H])=N1)C1=NC2=C(SC(=C2C([H])([H])[H])C([H])([H])N2C([H])([H])C([H])([H])N(C(=O)[C@@]([H])(N([H])[H])C([H])([H])[H])C([H])([H])C2([H])[H])C(=N1)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]N([H])C1=NC([H])=C(C([H])=N1)C1=NC2=C(SC(=C2C([H])([H])[H])C([H])([H])N2C([H])([H])C([H])([H])N(C(=O)C(N([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C2([H])[H])C(=N1)N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H]
[H]O[C@]([H])(C(=O)N1C([H])([H])C([H])([H])N(C([H])([H])C2=C(C3=C(S2)C(=NC(=N3)C2=C([H])N=C(N=C2[H])N([H])[H])N2C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H])C([H])([H])[H]
[H]OC(C(=O)N1C([H])([H])C([H])([H])N(C([H])([H])C2=C(C3=C(S2)C(=NC(=N3)C2=C([H])N=C(N=C2[H])N([H])[H])N2C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H])(C([H])([H])[H])C([H])([H])[H]
CS(=O)(=O)N1CCN(CC2=CN3C=C(N=C(N4CCOCC4)C3=N2)C2=CN=C(N)N=C2)CC1
CS(=O)(=O)N1CCN(CC2=C(Br)N3C=C(N=C(N4CCOCC4)C3=N2)C2=CN=C(N)N=C2)CC1
CC1=C(CN2CCN(CC2)S(C)(=O)=O)N=C2N1C=C(N=C2N1CCOCC1)C1=CN=C(N)N=C1
CS(=O)(=O)N1CCN(CC2=CN3C(=N2)C(=NC(=C3Cl)C2=CN=C(N)N=C2)N2CCOCC2)CC1
[H][C@@]12CC[C@@]([H])(N1C(C)(C)C(=O)NC)C1=NC(=NC(N3CCOC[C@@H]3C)=C1C2)C1=CC=C(NC(=O)NCC)C=C1
[H][C@@]12CC[C@@]([H])(N1C(=O)COC)C1=NC(=NC(N3CCOC[C@@H]3C)=C1C2)C1=CC=C(NC(=O)NCC)C=C1
[H][C@@]12CC[C@@]([H])(N1C(C)=O)C1=NC(=NC(N3CCOC[C@@H]3C)=C1C2)C1=CC=C(NC(=O)NCC)C=C1
[H][C@@]12CC[C@@]([H])(N1S(C)(=O)=O)C1=NC(=NC(N3CCOC[C@@H]3C)=C1C2)C1=CC=C(NC(=O)NCC)C=C1
[H][C@@]12CC[C@@]([H])(N1C1COC1)C1=NC(=NC(N3CCOC[C@@H]3C)=C1C2)C1=CC=C(NC(=O)NCC)C=C1
[H][C@]12CC[C@]([H])(N1C)C1=NC(=NC(N3CCOC[C@@H]3C)=C1C2)C1=CC=C(NC(=O)NCC)C=C1
[H][C@@]12CC[C@@]([H])(N1C(C)=O)C1=C(N=C(N=C1C2)C1=CC=C(NC(=O)NCC)C=C1)N1CCOC[C@@H]1C
[H][C@@]12CC[C@@]([H])(N1S(C)(=O)=O)C1=C(N=C(N=C1C2)C1=CC=C(NC(=O)NCC)C=C1)N1CCOC[C@@H]1C
[H][C@]12CC[C@]([H])(N1C1COC1)C1=C(N=C(N=C1C2)C1=CC=C(NC(=O)NCC)C=C1)N1CCOC[C@@H]1C
[H][C@@]12CC[C@@]([H])(N1CC)C1=C(N=C(N=C1C2)C1=CC=C(NC(=O)NCC)C=C1)N1CCOC[C@@H]1C
[H][C@]12CC[C@]([H])(N1C)C1=C(N=C(N=C1C2)C1=CC=C(NC(=O)NCC)C=C1)N1CCOC[C@@H]1C
CCNC(=O)NC1=CC=C(C=C1)C1=NC(N2CCOC[C@@H]2C)=C2CN(CCC2=N1)C1COC1
CC(C)(O)C1=NC=C(C=C1)C1=CN=C2NC(=O)CN(CC3CCOCC3)C2=N1
CC(C)(O)C1=NC=C(C=C1)C1=CN=C2NC(=O)N(CC3CCOCC3)C2=N1
O=C1CN(CCC2CCOCC2)C2=NC(=CN=C2N1)C1=CC=C(C=C1)C1=NNC=N1
O=C1NC2=NC=C(N=C2N1CCC1CCOCC1)C1=CC=C(C=C1)C1=NNC=N1
CNC(=O)C1=CC=CC(=C1)C1=CC=C2C(N=C(N=C2N2CCOC[C@@H]2C)N2CCOC[C@@H]2C)=N1
OP(O)(=O)O[C@H]1[C@@H](OCC2=CC=CC=C2)[C@H](OP(O)(O)=O)[C@@H](OP(O)(O)=O)[C@H](OP(O)(O)=O)[C@H]1OP(O)(O)=O
C[C@@H]1COCCN1C1=NC(=NC(=C1)C1(CC1)S(C)(=O)=O)C1=CC=CC2=C1C=CN2
CS(=O)(=O)C1(CCNCC1)C1=CC(=NC(=N1)C1=CC=CC2=C1C=CN2)N1CCOCC1
CS(=O)(=O)C1(CCOCC1)C1=CC(=NC(=N1)C1=CC=CC2=C1C=CN2)N1CCOCC1
CS(=O)(=O)C1(CC1)C1=CC(=NC(=N1)C1=CC=CC2=C1C=CN2)N1CCOCC1
CC(C)(C1=CC(=NC(=N1)C1=CC=CC2=C1C=CN2)N1CCOCC1)S(C)(=O)=O
O=C1C=C(OC2=C1SC=C2C1=CC=C2OCCOC2=C1)N1CCOCC1
O=C1C=C(OC2=C1SC=C2C1=CC=CC=C1)N1CCOCC1
C[C@H](O)C(=O)N1CCC(CC1)N1C(=O)N(C)C2=C1C1=NC(=CC=C1N=C2)C1=C2C=NNC2=CC=C1
CN1C(=O)N(C2CCN(CC2)C(C)=O)C2=C1C=NC1=CC=C(N=C21)C1=CN=C2NN=CC2=C1
CN1C(=O)N(C2CCN(CC2)C(C)=O)C2=C1C=NC1=CC=C(N=C21)C1=C2C=NNC2=CC=C1
COCC(=O)N1CCC(CC1)N1C(=O)N(C)C2=C1C1=NC(=CC=C1N=C2)C1=CC=C(C)N=C1
CN1C(=O)N(C2CCN(CC2)C(=O)C(C)(C)O)C2=C1C=NC1=CC=C(N=C21)C1=CC=C(C)N=C1
CN1C(=O)N(C2CCN(CC2)C(=O)CO)C2=C1C=NC1=CC=C(N=C21)C1=CC=C(C)N=C1
CN1C(=O)N(C2CCN(CC2)C(C)=O)C2=C1C=NC1=CC=C(N=C21)C1=CC=C(C)N=C1
COC1=CC=C(C=N1)C1=CC=C2N=CC3=C(N(C4CCN(CC4)C(C)=O)C(=O)N3C)C2=N1
COC1=CC=C(C=N1)C1=CC=C2N=CC3=C(N(C4CCN(C)CC4)C(=O)N3C)C2=N1
COC1=CC=C(C=N1)C1=CC=C2N=CC3=C(N([C@H]4CC[C@H](O)CC4)C(=O)N3C)C2=N1
COC1=CC=C(C=N1)C1=CC=C2N=CC3=C(N([C@H]4CC[C@@H](CC4)OCCO)C(=O)N3C)C2=N1
COC1=CC=C(C=N1)C1=CC=C2N=CC3=C(N(C(=O)N3C)C3=CC=C(C=C3)C(C)(C)C#N)C2=N1
CCNC(=O)NC1=CC=C(C=C1)C1=NC2=C(CCN(C2)C2COC2)C(=N1)N1CCOC[C@@H]1C
CCNC(=O)NC1=CC=C(C=C1)C1=NC2=C(CCN(C2)S(C)(=O)=O)C(=N1)N1CCOC[C@@H]1C
CCNC(=O)NC1=CC=C(C=C1)C1=NC2=C(CCN(C2)C2CCCC2)C(=N1)N1CCOC[C@@H]1C
CCNC(=O)NC1=CC=C(C=C1)C1=NC2=C(CCN(C2)C(C)C)C(=N1)N1CCOC[C@@H]1C
CCNC(=O)NC1=CC=C(C=C1)C1=NC2=C(CCN(C2)C2=NC=CN2C)C(=N1)N1CCOC[C@@H]1C
CCNC(=O)NC1=CC=C(C=C1)C1=NC2=C(CCN(C2)C2=NC=NC(C)=C2)C(=N1)N1CCOC[C@@H]1C
CCNC(=O)NC1=CC=C(C=C1)C1=NC2=C(CCN(C2)C2=NC=C(F)C=N2)C(=N1)N1CCOC[C@@H]1C
C[C@H]1COCCN1C1=NC(=NC2=C1CCN(C2)C1=NC=CC=N1)C1=CC=C(NC2=NC=CC(=O)N2)C=C1
O=C1NC(NC2=CC=C(C=C2)C2=NC3=C(CCN(C3)C3=NC=CC=N3)C(=N2)N2CCOCC2)=CC=C1
CCNC1=C(NC2=CC=C(C=C2)C2=NC3=C(CCN(C3)C3=NC=CC=N3)C(=N2)N2CCOC[C@@H]2C)C(=O)C1=O
C[C@H]1COCCN1C1=NC(=NC2=C1CCN(C2)C1=NC=CC=N1)C1=CC=C(NC2=NN(C)C(=O)N2)C=C1
C1CN(CCO1)C1=NC(=NC2=C1CCN(C2)C1=NC=CC=N1)C1=CC=C(NC2=NC=CC=N2)C=C1
FCCNC(=O)NC1=CC=C(C=C1)C1=NC2=C(CCN(C2)C2=NC=CC=N2)C(=N1)N1CCOCC1