[H]OC(=O)C([H])([H])OC1=C(Br)C([H])=C(C([H])=C1Br)C1=C2C([H])=C([H])C([H])=C([H])C2=C(Br)C2=C1C1=C([H])C([H])=C([H])C([H])=C1S2 [H]OC1=C(C(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C(=O)OC1=C([H])[H] [H]OC1=C(C(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C(=O)[C@]([H])(O1)C([H])([H])C(=O)OC1=C([H])C([H])=C(C([H])=C1[H])C1(N=N1)C(F)(F)F [H]OC1=C(C(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C(=O)[C@]([H])(O1)C([H])([H])C(=O)OC1=C([H])C([H])=C(C([H])=C1[H])C(=O)C1=C([H])C([H])=C([H])C([H])=C1[H] [H]OC1=C(C(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C(=O)[C@]([H])(O1)C([H])([H])OS(=O)(=O)C([H])([H])[H] [H]OC1=C(C(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C(=O)[C@]([H])(O1)C([H])([H])C(=O)OC1=C([H])C([H])=C([H])C(=C1[H])C(=O)C1=C([H])C([H])=C([H])C([H])=C1[H] [H]OC1=C(OC([H])([H])[H])C(=N[H])C(=O)C2=NC(=C([H])C([H])=C12)C1=NC(C(=O)OC([H])([H])[H])=C(C(=C1N([H])[H])C1=C(O[H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C([H])=C1[H])C([H])([H])[H] [H]OC1=C([H])\C(=N/C([H])([H])C([H])([H])C2=C([H])C(Br)=C(O[H])C(Br)=C2[H])C(=O)C2=NC([H])=C([H])C([H])=C12 [H]N(C1=C(Cl)C(=O)C2=C([H])C([H])=C([H])N=C2C1=O)C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H] [H]N(C1=C(Cl)C(=O)C2=C(C([H])=NN=C2[H])C1=O)C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H] [H]OC(=O)C([H])(C(=O)O[H])[C@@]([H])(C([H])([H])C(=O)C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C1=C(C([H])([H])[H])C([H])([H])C([H])([H])[C@]2([H])[C@]1(C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C2(C([H])([H])[H])C([H])([H])[H] [H]OS(=O)(=O)O[C@]([H])(C([H])([H])[C@@]1([H])C(=C([H])C([H])([H])[C@@]2([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[C@]12C([H])([H])[H])C([H])([H])[H])[C@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C1=C([H])OC([H])=C1[H] [H]OS(=O)(=O)O[C@@]([H])(C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[C@@]1([H])C(=C([H])C([H])([H])[C@@]2([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[C@]12C([H])([H])[H])C([H])([H])[H] [H]C1=C([H])C(=C([H])O1)C([H])([H])C([H])([H])C([H])([H])[C@@]([H])(C([H])([H])[H])[C@@]([H])(OS([O-])(=O)=O)C([H])([H])[C@@]1([H])C(=C([H])C([H])([H])[C@@]2([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[C@]12C([H])([H])[H])C([H])([H])[H] [H]OC(=O)C([H])(C(=O)O[H])[C@@]([H])(C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[C@@]1([H])[C@@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])[C@@]2([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[C@]12C([H])([H])[H] [H]N1C(=O)\C(=C(\[H])C2=C([H])C([H])=C(I)O2)C(=O)N(C1=S)C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H] [H]OS(=O)(=O)C([H])([H])C([H])([H])N1C(=S)S\C(=C(\[H])C2=C([H])N(N=C2C2=C([H])C([H])=C(OC([H])([H])C3=C([H])C([H])=C(Cl)C([H])=C3[H])C([H])=C2[H])C2=C([H])C([H])=C([H])C([H])=C2[H])C1=O [H]OS(=O)(=O)C([H])([H])C([H])([H])N1C(=S)S\C(=C(\[H])C2=C([H])N(N=C2C2=C([H])C([H])=C(OC([H])([H])C3=C(Cl)C([H])=C([H])C([H])=C3[H])C([H])=C2[H])C2=C([H])C([H])=C([H])C([H])=C2[H])C1=O [H]OS(=O)(=O)C([H])([H])C([H])([H])N1C(=S)S\C(=C(\[H])C2=C([H])N(N=C2C2=C([H])C([H])=C(OC([H])([H])C3=C(F)C([H])=C([H])C([H])=C3[H])C([H])=C2[H])C2=C([H])C([H])=C([H])C([H])=C2[H])C1=O [H]OS(=O)(=O)C([H])([H])C([H])([H])N1C(=S)S\C(=C(\[H])C2=C([H])N(N=C2C2=C([H])C([H])=C(OC([H])([H])C3=C([H])C([H])=C([H])C([H])=C3[H])C([H])=C2[H])C2=C([H])C([H])=C([H])C([H])=C2[H])C1=O [H]OC(=O)[C@]([H])(N1C(=S)S\C(=C(\[H])/C(/[H])=C(\[H])C2=C([H])C([H])=C([H])C([H])=C2[H])C1=O)C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H] [H]OC(=O)C([H])([H])SC1=C([H])C([H])=C(C([H])=C1[H])N1C(=C([H])C([H])=C1C([H])([H])[H])C([H])([H])[H] [H]OS(=O)(=O)C([H])([H])C([H])([H])N1C(=S)S\C(=C(\[H])C2=C([H])N(N=C2C2=C([H])C([H])=C(C([H])=C2[H])S(=O)(=O)N2C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])C2=C([H])C([H])=C([H])C([H])=C2[H])C1=O [H]N1N=C2C(=O)N(C(=O)C2=C1C(=O)OC([H])([H])C([H])([H])[H])C1=C([H])C([H])=C(Br)C([H])=C1[H] [H]N(C(=S)N([H])C1=C([H])C([H])=C([H])C2=C([H])C([H])=C([H])C([H])=C12)C1=C([H])C2=C(C([H])=C1[H])C1=C(O2)C([H])=C([H])C([H])=C1[H] [H]C1=C([H])C2=C(C([H])=C1[H])C(=O)C1=C(C(OC([H])([H])[H])=C([H])C([H])=C1OC([H])([H])[H])C2=O [H]OS(=O)(=O)C([H])([H])C([H])([H])N1C(=S)S\C(=C(\[H])C2=C([H])N(N=C2C2=C([H])C([H])=C(C([H])=C2[H])C([H])([H])[H])C2=C([H])C([H])=C([H])C([H])=C2[H])C1=O [H]OS(=O)(=O)C([H])([H])C([H])([H])N1C(=S)S\C(=C(\[H])C2=C([H])C([H])=C(O2)C2=C([H])C(Cl)=C([H])C([H])=C2[H])C1=O [H]N1C(=S)N([H])\C(=C(\[H])C2=C([H])C([H])=C(O2)C2=C([H])C(=C(C([H])=C2Br)C([H])([H])[H])C([H])([H])[H])C1=O [H]N1C([H])=C([H])C([H])=C1\C([H])=C1\C(=O)N([H])C(=S)N(C1=O)C1=C([H])C(Cl)=C([H])C([H])=C1[H] [H]OC(=O)C1=C([H])C([H])=C(C([H])=C1Cl)C1=C([H])C([H])=C(O1)C(\[H])=C1\C2=C(C(C#N)=C(N=C2C(C#N)=C1C([H])([H])[H])N([H])[H])C([H])([H])[H] [H]OS(=O)(=O)C([H])([H])C([H])([H])N1C(=S)S\C(=C(\[H])C2=C([H])N(N=C2C2=C([H])C([H])=C(C([H])=C2[H])S(=O)(=O)N2C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C2=C([H])C([H])=C([H])C([H])=C2[H])C1=O [H]OS(=O)(=O)C([H])([H])C([H])([H])N1N([H])\C(SC1=S)=C(/[H])\C(\[H])=C(/[H])C1=C([H])C([H])=C([H])C([H])=C1[H] [H]N(C(=O)C(\[H])=C(/[H])C1=C([H])C([H])=C(O1)C1=C([H])C([H])=C([H])C([H])=C1[N+]([O-])=O)C1=C([H])C([H])=C(C([H])=C1[H])C1=NC2=C([H])C([H])=C([H])C([H])=C2O1 [H]OS(=O)(=O)C([H])([H])C([H])([H])N1C(=S)S\C(=C(\[H])C2=C([H])N(N=C2C2=C([H])C([H])=C(OC([H])([H])[H])C([H])=C2[H])C2=C([H])C([H])=C([H])C([H])=C2[H])C1=O [H]OS(=O)(=O)C([H])([H])C([H])([H])N1C(=S)S\C(=C(\[H])C2=C([H])N(N=C2C2=C([H])C([H])=C(Cl)C([H])=C2[H])C2=C([H])C([H])=C([H])C([H])=C2[H])C1=O [H]N1C(=O)S\C(=C(\[H])C2=C([H])C([H])=C(O2)C2=C([H])C([H])=C(C([H])=C2[H])[N+]([O-])=O)C1=S [H]N([H])S(=O)(=O)C1=C([H])C([H])=C(N([H])C(=S)N([H])C2([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])=C1[H] [H]C1=C([H])C(=C([H])C([H])=C1OC([H])([H])[H])C1=NOC(=N1)C([H])([H])SC1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H] [H]N(C(=O)C1=C([H])C([H])=C(OC([H])([H])C([H])([H])OC2=C([H])C([H])=C([H])C([H])=C2[H])C([H])=C1[H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H] [H]N([H])C1=C(C([H])=NN1C1=NN=C(C([H])=C1[H])C([H])([H])C1=C(Cl)C([H])=C(Cl)C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H] [H]OC1=C(C([H])=C(\C([H])=C2/SC(=O)N(C2=O)C2=C([H])C([H])=C(Cl)C([H])=C2[H])C([H])=C1OC([H])([H])[H])[N+]([O-])=O [H]N(C(=O)C([H])([H])OC1=C([H])C(=C(Cl)C([H])=C1[H])C([H])([H])[H])C1=NN(N=N1)C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H] [H]OC1=C(C([H])=C(\C([H])=C2/SC(=O)N(C2=O)C2=C([H])C(Cl)=C([H])C([H])=C2[H])C([H])=C1OC([H])([H])[H])[N+]([O-])=O [H]\C(=C(\[H])[C@]1([H])N2C(S[C@]([H])(C2=O)C([H])([H])[H])=NC(=C1C(=O)OC([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H] [H]C1=C([H])C([H])=C(S1)C(=O)C1=NO[N+]([O-])=C1C(=O)C1=C([H])C([H])=C([H])S1 [H]C1=NN(C2=NC(=O)N(C(=O)C2=N1)C([H])([H])[H])C([H])([H])[H] [H]N([H])C1=C(SC(=S)N1C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H])C(=O)N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H] [H]N([H])C1=C(SC(=S)N1C1=C([H])C([H])=C([H])C([H])=C1[H])C(=O)N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H] [H]OC1=C(O[H])C2=C3C(=C1[H])C(=O)OC1=C3C(=C([H])C(O[H])=C1O[H])C(=O)O2 [H]S\C(N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])=C1\C([H])=C([H])C(=O)C(OC([H])([H])[H])=C1[H] [H]N(C(=O)C1=C(OC([H])=C1[H])C([H])([H])[H])C1=C(C([H])=C(C([H])=C1C([H])([H])[H])C([H])([H])[H])C([H])([H])[H] [H]C1=C([H])C(=C([H])C([H])=C1OC([H])([H])[H])N1C(=O)[C@@]2([H])N(C([H])([H])C([H])([H])C2([H])[H])[C@@]1([H])C1=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C(OC([H])([H])[H])=C1[H] [H]C1=C(C(=S)N2C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C2=C([H])C([H])=C([H])C([H])=C2N1C([H])([H])C([H])([H])OC1=C([H])C([H])=C([H])C([H])=C1[H] [H]C1=C([H])C([H])=C(C(=O)N2C([H])([H])C([H])([H])C([H])([H])[C@]([H])(C(=O)OC([H])([H])C([H])([H])[H])C2([H])[H])C(SC([H])([H])C([H])([H])[H])=C1[H] [H]N(C(=O)N([H])C1=C([H])C(Cl)=C(Cl)C([H])=C1[H])C1=NN=C(S1)C1=C([H])C([H])=NC([H])=C1[H] [H]N(C(=O)C1=C(N=C([H])C([H])=C1[H])N1C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H] [H]N(N([H])C(=O)C([H])([H])OC1=C([H])C2=C(C([H])=C1[H])C(=C([H])C(=O)O2)C([H])([H])[H])C(\[H])=C1/C([H])=C(C([H])=C([H])C1=O)[N+]([O-])=O [H]C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C(O[C@@]([H])(C(=O)O[C@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])[H])C([H])([H])[H])C([H])=C1[H] [H]N(C(=O)C1([H])C([H])([H])C([H])([H])N(C(=O)C2=C([H])C([H])=C([H])C([H])=C2Cl)C([H])([H])C1([H])[H])C1=C([H])C(F)=C([H])C([H])=C1[H] [H]N([H])C(=S)N1N=C(\C(=N/N([H])C2=C(C(=C([H])C([H])=C2[H])[N+]([O-])=O)C([H])([H])[H])C1=O)C1=C([H])C([H])=C(C([H])=C1[H])[N+]([O-])=O [H]OC(=O)C([H])([H])SC1=C([H])C(=C([H])N2C(=O)C3=C(SC(C(=O)OC([H])([H])C([H])([H])[H])=C3C([H])([H])[H])N=C12)C(=O)C1=C([H])C([H])=C([H])C([H])=C1O[H] [H]N1C(=S)N(C(=O)\C(=C(\[H])C2=C([H])C([H])=C(C([H])=C2[H])N2C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C1=O)[C@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])[H] [H]OC1=C(C([H])=C(\C([H])=C2/SC(=O)N(C2=O)C([H])([H])C2=C([H])C([H])=C(Cl)C([H])=C2[H])C([H])=C1OC([H])([H])[H])[N+]([O-])=O [H]OC(=O)C([H])([H])OC1=C([H])C([H])=C(\C([H])=C2/S\C(=N/C3=C([H])C([H])=C(OC([H])([H])[H])C([H])=C3[H])N(C2=O)C([H])([H])C([H])([H])C2=C([H])N([H])C3=C([H])C([H])=C([H])C([H])=C23)C([H])=C1[H] [H]N(C1=C([H])C2=C(OC3=C2C(=O)C([H])([H])C(C([H])([H])[H])(C([H])([H])[H])C3([H])[H])C2=C([H])C([H])=C([H])C([H])=C12)S(=O)(=O)C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H] CC1=CC=C(NC(=O)CN2C(=O)\C(=N/NC(=O)C3=C(O)C=CC(=C3)N(O)=O)C3=CC=CC=C23)C=C1 [H]OC(=O)C([H])([H])C([H])([H])SC1=C([H])C(=C([H])N2C(=O)C3=C(SC(C(=O)OC([H])([H])C([H])([H])[H])=C3C([H])([H])[H])N=C12)C(=O)C1=C(O[H])C([H])=C([H])C(OC([H])([H])[H])=C1[H] [H]\C(C1=C([H])C([H])=C([H])O1)=C1\SC2=NC3=C(N=C([H])C(Br)=C3[H])N2C1=O [H]\C(C1=C([H])C([H])=C(O1)C1=C([H])C([H])=C([H])C([H])=C1[N+]([O-])=O)=C1\SC2=NC3=C(N=C([H])C(Br)=C3[H])N2C1=O [H]OC(=O)C1=C([H])C([H])=C([H])C([H])=C1C1=C([H])C([H])=C(O1)C(\[H])=C1/SC2=NC3=C(C([H])=C(C([H])=C3N2C1=O)C([H])([H])[H])C([H])([H])[H] [H]OC(=O)C([H])([H])OC1=C(OC([H])([H])[H])C([H])=C(\C([H])=C2\SC3=NC(=C(C(=O)OC([H])([H])C([H])([H])[H])[C@]([H])(N3C2=O)C2=C([H])C([H])=C([H])C([H])=C2Cl)C([H])([H])[H])C([H])=C1Cl [H]OC(=O)C([H])([H])OC1=C(Cl)C([H])=C(\C([H])=C2/SC3=NC(=C(C(=O)OC([H])([H])C([H])([H])[H])[C@]([H])(N3C2=O)C2=C([H])C(OC([H])([H])[H])=C([H])C([H])=C2[H])C([H])([H])[H])C([H])=C1Cl [H]S\C(N([H])C([H])([H])C1=C([H])C(=C(F)C([H])=C1[H])C(F)(F)F)=C1/C([H])=C([H])C(=O)C(OC([H])([H])[H])=C1[H] [H]N(C(=S)N([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C(Cl)C([H])=C([H])C([H])=C1Cl [H]OC(=O)C1=C([H])C([H])=C(N([H])C(=S)N([H])C(=O)C2=C([H])C([H])=C(O2)C2=C([H])C([H])=C(Br)C([H])=C2[H])C([H])=C1[H] [H]OC(=O)C([H])([H])OC1=C(OC([H])([H])[H])C([H])=C(\C([H])=C2/SC(=O)N(C2=O)C([H])([H])C(=O)N([H])C2=C([H])C([H])=C(C([H])=C2[H])C([H])([H])[H])C([H])=C1Cl [H]OC(=O)C([H])([H])OC1=C([H])C([H])=C(\C([H])=C2/SC3=NC(=C(C(=O)OC([H])([H])C([H])([H])[H])[C@]([H])(N3C2=O)C2=C([H])C([H])=C(SC([H])([H])[H])C([H])=C2[H])C([H])([H])[H])C([H])=C1[H] [H]OC(=O)C([H])([H])OC1=C([H])C([H])=C(\C([H])=C2/SC3=NC(=C(C(=O)OC([H])([H])C([H])([H])[H])[C@]([H])(N3C2=O)C2=C([H])C([H])=C(Cl)C([H])=C2[H])C([H])([H])[H])C([H])=C1[H] [H]OC(=O)C1=C([H])C([H])=C([H])C([H])=C1C1=C([H])C([H])=C(O1)C(\[H])=C1/SC2=NC3=C(C([H])=C([H])C(=C3C([H])([H])[H])C([H])([H])[H])N2C1=O [H]OC(=O)C1=C([H])C([H])=C([H])C([H])=C1C1=C([H])C([H])=C(O1)C(\[H])=C1\SC2=NC3=C(C([H])=C(C(=C3[H])C([H])([H])[H])C([H])([H])[H])N2C1=O [H]\C(C1=C([H])C([H])=C(O1)C1=C([H])C(Cl)=C([H])C(Cl)=C1[H])=C1\SC2=NC3=C(N=C([H])C(Br)=C3[H])N2C1=O [H]C1=C([H])C([H])=C(O1)C1=C(N=C(SC([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])N=N1)C1=C([H])C([H])=C([H])O1 [H]OC(=O)C1=C([H])C([H])=C([H])C([H])=C1C1=C([H])C([H])=C(O1)C(\[H])=C1/SC2=NC3=C(N=C([H])C(Br)=C3[H])N2C1=O [H]N(C(=O)N([H])C([H])([H])C([H])([H])OC([H])([H])[H])C1=C([H])C2=C(N=C(C3=C([H])C([H])=C([H])O3)C(=N2)C2=C([H])C([H])=C([H])O2)C([H])=C1[H] [H]N(C(=S)N(C([H])([H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])C1=C([H])C(Cl)=C(OC([H])([H])[H])C([H])=C1[H] [H]OC(=O)C([H])([H])OC1=C(OC([H])([H])[H])C([H])=C(\C([H])=C2/SC(=NC2=O)N([H])C2=C([H])C([H])=C(C([H])=C2[H])C([H])([H])C([H])([H])[H])C([H])=C1Br [H]N([H])C1=C(SC(=S)N1C1=C([H])C([H])=C([H])C(=C1[H])C([H])([H])[H])C(=O)N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H] [H]OC(=O)C([H])([H])SC1=C([H])C(=C([H])N2C(=O)C3=C(SC([H])=C3C3=C([H])C([H])=C([H])C([H])=C3[H])N=C12)C(=O)C1=C([H])C([H])=C([H])C([H])=C1O[H] [H]N([H])S(=O)(=O)C1=C(Cl)C([H])=C([H])C(=C1[H])C(=O)N([H])[C@]1([H])C2=C([H])C([H])=C([H])C([H])=C2SC([H])([H])C1([H])[H] [H]S\C(N([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])=C1/C([H])=C([H])C(=O)C(OC([H])([H])[H])=C1[H] [H]S\C(N([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])=C1/C([H])=C([H])C(=O)C(OC([H])([H])[H])=C1[H] [H]N(C1=NC([H])=NC2=C1N([H])C1=C2C([H])=C(OC([H])([H])[H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])N1C(=O)C([H])([H])C([H])([H])C1([H])[H] [H]C([H])([H])N1N=C(N=C2C(=O)N(C(=O)N=C12)C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[H] [H]N=C1N2N=C(SC2=NC(=O)\C1=C(/[H])C1=C([H])C([H])=C([H])N1C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])C1=C([H])C([H])=C([H])O1 [H]C1=NC2=C(C([H])=C1[H])C([H])=C([H])C([H])=C2S(=O)(=O)N(C(=O)C([H])(C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H] [H]OC(=O)C([H])([H])OC1=C([H])C([H])=C(\C([H])=N\N([H])C(=O)C2=C([H])C([H])=C(C([H])=C2[H])C2=C([H])SC(=N2)N([H])C2=C([H])C([H])=C(Cl)C([H])=C2[H])C([H])=C1[H] [H]OC(=O)C1=C([H])C([H])=C(N([H])C(=O)C([H])([H])SC2=NC(=NC3=C2C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2O3)C2=C([H])C([H])=C(F)C([H])=C2[H])C([H])=C1[H] [H]OC(=O)C1=C([H])C(=C([H])C([H])=C1[H])N1C([H])=C([H])C([H])=C1\C([H])=C1\N([H])C(=O)N(C1=O)C1=C([H])C([H])=C(Cl)C([H])=C1[H] [H]N=C1N2N=C(SC2=NC(=O)\C1=C(/[H])C1=C([H])C([H])=C([H])N1C1=C([H])C([H])=C(Br)C([H])=C1[H])C([H])([H])C([H])([H])[H] [H]OC(=O)C([H])([H])SC1=NC(SC([H])([H])[H])=NC2=C1SC1=C2C2=C(C(=N1)C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C2([H])[H] [H]N([H])N1C(SC([H])([H])C(=O)N([H])[C@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])[H])=NN=C1C1=C([H])C([H])=C(Cl)C([H])=C1[H] [H]N(C(=O)N([H])C([H])([H])C1=C([H])C([H])=C([H])O1)C(=O)C([H])([H])SC1=NN2C(=N1)N=C(C([H])=C2C([H])([H])[H])C([H])([H])[H] [H]N([H])C1=N[C@]([H])(C2=C([H])C([H])=C(OC([H])([H])C3=C([H])C([H])=C(C([H])=C3[H])C(=O)OC([H])([H])[H])C([H])=C2[H])C(C(=O)OC([H])([H])C([H])([H])[H])=C(N1[H])C1=C([H])C([H])=C([H])C([H])=C1[H] [H]N(N([H])C(=O)C1=C([H])C([H])=C(Cl)C([H])=C1[H])C(=O)C1=NN2C(=N1)N=C(C([H])=C2C([H])([H])[H])C([H])([H])[H] [H]N(C(=O)C([H])([H])SC1=NC2=C([H])C([H])=C([H])C([H])=C2O1)C1=C([H])C([H])=C([H])C([H])=C1C([H])([H])[H] [H]C1=C([H])C([H])=C(C([H])=C1[H])C1=C2N=C(C([H])=C(N2N=C1C([H])([H])[H])N1C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])[H])C([H])([H])C1([H])[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H] [H]O[C@@]1([H])[C@@]2(C([H])([H])C3=C([H])C([H])=C([H])C([H])=C3[H])C([H])([H])[N@]3C([H])([H])[C@]1(C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[N@@](C2([H])[H])C([H])([H])C3([H])[H] [H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1C(=O)C2=C(OC3=C(C([H])=C([H])C(OC([H])([H])[H])=C3[H])C2=O)N=C1C([H])([H])C([H])([H])[H] [H]C1=C([H])C(=C([H])C([H])=C1F)N1C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C(=O)OC3=C2C([H])=C2C(=C3[H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H] [H]N(C(=O)C([H])([H])[H])[C@@]1([H])C(=O)N(C2=C1C([H])=C(Br)C([H])=C2[H])C([H])([H])[H] [H]C1=C([H])C([H])=C(O1)C([H])([H])N1C(=O)N(C2=C(C3=C(S2)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C3([H])[H])C1=O)C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H] [H]N(C(=O)C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])[C@@]1(C(=O)N(C2=C1C(=O)C([H])([H])C(C([H])([H])[H])(C([H])([H])[H])C2([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C(F)(F)F [H]\C(=N/N1C([H])=NN=C1[H])C1=C([H])C([H])=C(S1)C([H])([H])[H] [H]C1=C([H])C2=C(N=C3N(C2=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C3([H])[H])C([H])=C1C(=O)N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H] [H]OC(=O)C1=C(C2=C(S1)N=C(N([H])C2=O)C(\[H])=C(/[H])C1=C([H])C(=C(C([H])=C1[H])C([H])([H])[H])[N+]([O-])=O)C([H])([H])[H] [H]C([H])([H])C([H])([H])C(=O)C1=C(N2C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C1=O [H]N(C(=O)[C@@]12OC([H])([H])[C@]3(C([H])([H])[H])[C@@]([H])(C([H])([H])C([H])([H])[C@]13C([H])([H])[H])C2([H])[H])C1=NC([H])=C([H])S1 [H]N(C1=NN=C(O1)C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])C1=NC2=C(OC([H])([H])[H])C([H])=C([H])C([H])=C2S1 [H]N(C(=O)C1=C(Cl)C([H])=C([H])C(=C1[H])N1C([H])=NN=C1[H])C1=C(C([H])=C([H])C(=C1[H])C1=NC2=C([H])C([H])=C([H])C([H])=C2S1)C([H])([H])[H] [H]N(C(=O)C([H])([H])SC1=NC2=C([H])C([H])=C([H])C([H])=C2C([H])=C1[H])C1=NSC(=N1)C1=C([H])C([H])=C(Cl)C([H])=C1[H] [H]N1N=C(SC([H])([H])C(=O)N2C3=C([H])C([H])=C([H])C([H])=C3C([H])([H])C2([H])[H])N(\C1=C1/C([H])=NC2=C([H])C([H])=C([H])C([H])=C12)C1=C([H])C([H])=C(OC([H])([H])C([H])([H])[H])C([H])=C1[H] [H]N([H])S(=O)(=O)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])N([H])C1=NC2=C(N=NN2C2=C([H])C([H])=C([H])C([H])=C12)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H] [H]N(C(=O)C1=C([H])C(=NC2=C1C([H])=C(Br)C([H])=C2[H])C1=C([H])C([H])=NC([H])=C1[H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1OC([H])([H])[H] [H]N(C(=O)C1=C([H])C(=NC2=C1C([H])=C(C([H])=C2[H])C([H])([H])[H])C1=C([H])C([H])=NC([H])=C1[H])C1=C([H])C([H])=C(OC([H])(F)F)C([H])=C1[H] [H]N(C(=O)C1=C([H])C(=NC2=C1C([H])=C(Br)C([H])=C2[H])C1=C([H])C([H])=C([H])C([H])=N1)C1=C([H])C([H])=NC([H])=C1[H] [H]N(C(=O)C1=C([H])C2=C(OC([H])([H])C([H])([H])O2)C([H])=C1[H])C1=C([H])C2=C(OC(=N2)C2=C([H])N=C([H])C([H])=C2[H])C([H])=C1[H] [H]N(C(=O)C([H])([H])N1C(=O)N([H])[C@](C1=O)(C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])[H])C1=C(C([H])=C(S1)C1=C([H])C([H])=C([H])C([H])=C1[H])C(=O)OC([H])([H])C([H])([H])[H] [H]C1=NC(C#CC2=C([H])C3=C(C([H])=C2[H])C(=O)C2=C([H])C([H])=C([H])C([H])=C2N3C([H])([H])[H])=C([H])C([H])=C1[H] [H]C1=NC(Cl)=C(C([H])=C1[H])C1=NN(N=N1)C1=C([H])N=C(Cl)C([H])=C1[H] [H]C1=C([H])C([H])=C2C([H])=C(C3=NN(N=N3)C3=C([H])N=C(Cl)C([H])=C3[H])C(Cl)=NC2=C1[H] [H]N([H])S(=O)(=O)C1=C([H])C([H])=C(N([H])C(=S)N([H])C2([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C([H])=C1[H] [H]OC1=C(C(=O)OC([H])([H])C([H])([H])O[C@@]([H])(C([H])([H])C([H])([H])[H])[C@@]([H])(C(=O)OC([H])([H])[C@@]2([H])OC(=O)C(C(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])=C2O[H])C([H])([H])[H])C(=O)O[C@]1([H])C([H])([H])O[H] [H]N(C1=NN=C(O1)C1=C([H])C([H])=C(F)C([H])=C1[H])C1=NC2=C(OC([H])([H])[H])C([H])=C([H])C([H])=C2S1 [H]N(C1=NN=C(O1)C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])C1=NC2=C(F)C([H])=C([H])C([H])=C2S1 [H]N(C1=NN=C(O1)C1=C([H])C2=C(OC([H])([H])C([H])([H])O2)C([H])=C1[H])C1=NC2=C(S1)C([H])=C(SC([H])([H])[H])C([H])=C2[H] [H]N1C([H])=C([H])C(Cl)=C1C1=C([H])C([H])=C(O1)C(=C1/N=C([H])C([H])=C1[H])\C([H])([H])[H] [H]N1C([H])=C([H])C([H])=C1C1=C([H])C([H])=C(O1)C(=C1/N=C([H])C([H])=C1[H])\C([H])([H])[H] [H]C([H])=C([H])C([H])([H])C(\[H])=C(/C1=C([H])C([H])=C(N1[H])C1=N\C(=C(\[H])C2=C([H])C([H])=C(N2[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])=C([H])[H])C(OC([H])([H])[H])=C1[H])C([H])([H])[H] [H]C([H])=C([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C(N1[H])C(\[H])=C1/N([H])C(=O)C([H])=C1OC([H])([H])[H] [H]N1C(=O)N(C2=C(N(C(SC([H])([H])C([H])([H])N3C([H])([H])C([H])([H])C([H])([H])C([H])([H])C3([H])[H])=N2)C([H])([H])C([H])([H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C1=O)C([H])([H])[H] [H]N(C(=O)[C@@]([H])(N1C(=O)C2=C([H])C([H])=C([H])C([H])=C2C1=O)C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])N1C([H])=NC([H])=C1[H] [H]C1=C([H])C([H])=C(C2=NO[C@]3([H])C(=O)N(C(=O)[C@]23[H])C2=C(OC([H])([H])[H])C([H])=C([H])C(OC([H])([H])[H])=C2[H])C(Cl)=C1[H] [H]C1=C([H])C([H])=C2C(=O)N(SC2=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C(=O)OC([H])([H])C([H])([H])[H] [H]N([H])S(=O)(=O)C1=C([H])C([H])=C(N([H])C(=O)C([H])([H])OC(=O)C2=C([H])C([H])=C(C([H])=C2[H])N(C([H])([H])[H])C([H])([H])[H])C([H])=C1[H] [H]N(C1=NN2C(S1)=NC1=C([H])C([H])=C([H])C([H])=C1C2=O)C1=C([H])C([H])=C([H])C(=C1[H])C([H])([H])[H] [H]OC([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C(=S)C2=C([H])C(Cl)=C(Cl)C([H])=C2[H])C([H])([H])C1([H])[H] [H]N(C(=O)OC([H])([H])[H])C1=C(C(=O)OC([H])([H])C([H])([H])[H])C(=C(S1)C(=O)N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H])C([H])([H])[H] [H]N(C(=O)C([H])([H])OC1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])[H])C1=C([H])C(=O)\C(C([H])=C1[H])=C1\OC2=C([H])C([H])=C([H])C([H])=C2N1[H] [H]OS(=O)(=O)C1=C(OC2=C([H])C([H])=C([H])C([H])=C2[H])C([H])=C([H])C(=C1[H])N1N([H])C(=C(C1=O)C([H])([H])C([H])([H])[H])C([H])([H])[H] [H]OC(=O)C1=C(C([H])=C([H])[H])C([H])([H])S[C@]2([H])N1C(=O)[C@@]2([H])N([H])C(=O)C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H] [H]C1=C([H])C(=C([H])C(Cl)=C1Cl)C(=S)N1C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])[H])C([H])([H])C1([H])[H] [H]C1=C([H])C(=C([H])C([H])=C1Cl)C(=S)N1C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])[H])C([H])([H])C1([H])[H] [H]OC(=O)C1=C([H])C([H])=C(O1)C([H])([H])S(=O)(=O)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H] [H]N(C(=O)C(Cl)(Cl)Cl)P(=O)(N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H])N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H] [H]N1C(SC([H])([H])C(=O)N2C3=C([H])C([H])=C([H])C([H])=C3C(=C2C([H])([H])[H])C([H])([H])[H])=NC2=C([H])C([H])=C([H])C([H])=C12 [H]OC1=C([H])C2=C(OC(=O)C(=C2[H])C2=NN(C([H])=C2C([H])=O)C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])=C1[H] [H]N(\N=C(/[H])C1=C([H])N(N=C1C([H])([H])[H])C([H])([H])[H])C(=S)N([H])C1=C([H])C([H])=C([H])C([H])=C1[H] [H]N(C(=O)C([H])([H])N([H])C(=O)C1=NN(C(=O)C2=C([H])C([H])=C([H])C([H])=C12)C1=C([H])C(Cl)=C(OC([H])([H])[H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=N1 [H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1C([H])([H])C([H])([H])N(C(=S)C2=C([H])C([H])=C(Br)C([H])=C2[H])C([H])([H])C1([H])[H] [H]C1=C([H])C(=C([H])C([H])=C1Br)C(=S)N1C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])[H])C([H])([H])C1([H])[H] [H]OC([H])([H])C([H])([H])N1C([H])([H])C([H])([H])N(C(=S)C2=C([H])C([H])=C(Br)C([H])=C2[H])C([H])([H])C1([H])[H] [H]N(C(=O)C1=C([H])C(=NC2=C([H])C([H])=C([H])C([H])=C12)C1=C([H])C(OC([H])([H])[H])=C([H])C([H])=C1[H])C1=NC2=C([H])C([H])=C([H])C([H])=C2S1 [H]N(\N=C(/[H])C1=C([H])C([H])=C(OC(=O)C2=C([H])C([H])=C([H])S2)C([H])=C1[H])C(=O)C1=C([H])C(F)=C([H])C([H])=C1[H] [H]N([H])C(=N/OC(=O)C1=C([H])C([H])=C([H])C2=C([H])C([H])=C([H])C([H])=C12)\C1=C([H])C(=C([H])C([H])=C1[H])[N+]([O-])=O [H]OC(=O)C([H])([H])[C@@]1([H])SC(=NC1=O)N([H])\N=C(/[H])C1=C([H])C(OC([H])([H])C2=C(Cl)C([H])=C(Cl)C([H])=C2[H])=C(OC([H])([H])[H])C([H])=C1[H] [H]N(N([H])C(=O)C1=C([H])C(Br)=C(C([H])=C1[H])C([H])([H])[H])C(=O)C1=C([H])C([H])=C(N([H])C(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])=C1[H] [H]N(C(=O)C1=C([H])C(=C(OC([H])([H])C([H])([H])[H])C([H])=C1[H])[N+]([O-])=O)C1=C(Cl)C([H])=C([H])C(=C1[H])C1=NC2=C([H])C([H])=C([H])C([H])=C2N1[H] [H]N(C(=O)C1=C([H])C(=C([H])C(=C1[H])[N+]([O-])=O)C(=O)OC([H])([H])[H])C1=NN=C(S1)C([H])(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H] [H]N1N=C(N(\N=C(/[H])C2=C([H])C([H])=C(Br)S2)C1=S)C1=C([H])N=C([H])C([H])=C1[H] [H]N(N([H])C(=O)C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C(=O)C1=C([H])C([H])=C(N([H])C(=O)C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])=C1[H] [H]N(C(=S)N(C([H])([H])C1=C([H])N(C2=C([H])C([H])=C([H])C([H])=C12)C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C1=C(OC([H])([H])[H])C([H])=C([H])C(Cl)=C1[H] [H]N(C(=S)N(C([H])([H])C1=C([H])N(C2=C([H])C([H])=C([H])C([H])=C12)C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C1=C(OC([H])([H])[H])C([H])=C(Cl)C([H])=C1[H] [H]N(C(=S)N(C([H])([H])C([H])([H])OC([H])([H])[H])[C@]([H])(C1=C([H])N=C([H])C([H])=C1[H])C([H])([H])[H])C1=C(C([H])=C(C([H])=C1C([H])([H])[H])C([H])([H])[H])C([H])([H])[H] [H]N(C(=S)N1C([H])([H])C([H])([H])C([H])(N(C([H])([H])[H])C([H])([H])[C@@]2([H])OC([H])([H])C([H])([H])C2([H])[H])C([H])([H])C1([H])[H])C1=C([H])C(Cl)=C(OC([H])([H])[H])C([H])=C1[H] [H]N([H])C1=C(N([H])C2=C([H])C([H])=C([H])C([H])=C2OC([H])([H])[H])C([H])=C([H])C(=C1[H])[N+]([O-])=O [H]N(\N=C(/[H])C1=C([H])C([H])=C(Br)S1)C(=O)C1=C([H])C(=C([H])C([H])=C1[H])[N+]([O-])=O [H]N1C(=NC2=C([H])C([H])=C([H])C([H])=C12)C(\C#N)=C(/[H])C1=C([H])C([H])=C(OC(=O)C2=C([H])C([H])=C(Cl)S2)C([H])=C1[H] [H]N([H])C1=C(C2=NC3=C([H])C([H])=C([H])C([H])=C3O2)C2=C(N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C(=O)N(N=C2[N+]([O-])=O)C([H])([H])[H] [H]N(C(=S)N([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C1=C([H])C(=C(C([H])=C1[H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])S(=O)(=O)N([H])C1=C([H])C([H])=C([H])C([H])=C1OC([H])([H])[H] [H]N(\N=C(/[H])C1=C([H])C([H])=C(Br)C([H])=C1[H])C(=O)C1=C([H])C([H])=C(Br)O1 [H]N([H])S(=O)(=O)C1=C([H])C([H])=C(N([H])C(=S)N([H])C([H])([H])C([H])([H])C([H])([H])OC([H])(C([H])([H])[H])C([H])([H])[H])C([H])=C1[H] [H]N(\N=C(/[H])C1=C([H])C(=C(Cl)C([H])=C1[H])[N+]([O-])=O)C(=O)C1=C([H])C2=C(OC([H])([H])C([H])([H])O2)C([H])=C1[H] [H]N(\N=C(/[H])C1=C([H])C([H])=NC([H])=C1[H])C(=O)C1=C([H])C(=C([H])C([H])=C1[H])S(=O)(=O)N([H])C1=C([H])C([H])=C(Cl)C([H])=C1[H] [H]OC1=C([H])C([H])=C([H])C([H])=C1C(=O)N([H])\N=C(/[H])C1=C([H])C([H])=C(OC([H])([H])C(=O)N([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])=C1[H] [H]N(C(=S)N(C([H])([H])C([H])([H])C([H])([H])OC([H])([H])[H])[C@]([H])(C1=C([H])C([H])=C([H])C([H])=N1)C([H])([H])[H])C1=C(C([H])=C(C([H])=C1C([H])([H])[H])C([H])([H])[H])C([H])([H])[H] [H]N(C(=S)N(C([H])([H])C1=C([H])C([H])=C([H])S1)C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])C1([H])[H])C1=C([H])C(Cl)=C(OC([H])([H])[H])C([H])=C1[H] [H]N(C(=S)N([H])C([H])([H])[C@]1([H])C([H])([H])N(C([H])([H])C1([H])[H])[C@@]([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H])C1=C(C([H])=C(C([H])=C1C([H])([H])[H])C([H])([H])[H])C([H])([H])[H] [H]OC1=C([H])C([H])=C(C([H])=C1[H])C(=O)N([H])\N=C(/[H])C1=C([H])C([H])=C(OC([H])([H])C(=O)N([H])C2=C([H])C(=C([H])C([H])=C2[H])[N+]([O-])=O)C([H])=C1[H] [H]N1C(=S)N([H])[C@]([H])(C([H])=C1[C@]12C([H])([H])[C@@]3([H])C([H])([H])[C@]([H])(C([H])([H])[C@]([H])(C3([H])[H])C1([H])[H])C2([H])[H])C1=C([H])C2=C(OC([H])([H])O2)C([H])=C1[H] [H]OC(=O)C1=C([H])C2=C(C([H])=C1[H])C(=O)N(C2=O)C1=C([H])C([H])=C([H])C(=C1[H])C1=NC2=C([H])C([H])=C([H])C([H])=C2S1 [H]C1=C([H])C(=C([H])C([H])=C1OC([H])([H])C([H])([H])[H])C(=S)N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H] [H]N(C(=S)N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H])C1=C([H])C(OC([H])([H])[H])=C(Cl)C([H])=C1OC([H])([H])[H] [H]N(C(=O)C1=C([H])C([H])=C([H])C(=C1[H])C1=C([H])C2=C([H])C([H])=C([H])C([H])=C2OC1=O)C1=NC2=C(S1)C([H])=C(OC([H])([H])[H])C([H])=C2[H] [H]N(C(=S)N([H])C([H])([H])C1=C([H])C([H])=C(O1)C([H])([H])N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C1=C(C([H])=C(C([H])=C1C([H])([H])[H])C([H])([H])[H])C([H])([H])[H] [H]C1=C(OC(=C1[H])C1=C([H])C(=C([H])C([H])=C1[H])[N+]([O-])=O)C(=S)N1C([H])([H])C([H])([H])N(C2=C([H])C([H])=C([H])C([H])=C2C([H])([H])[H])C([H])([H])C1([H])[H] [H]N(C(=O)[C@@]([H])(OC(=O)C1=C([H])C(=C(C([H])=C1[H])C([H])([H])[H])S(=O)(=O)N(C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])[H])C([H])([H])[H])C1=C([H])C2=C(OC([H])([H])C([H])([H])O2)C([H])=C1[H] [H]SC(N1C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])[H])C([H])([H])C1([H])[H])=C1C([H])=C([H])C(=O)C([H])=C1[H] [H]N(C(=O)C1=C(C([H])=C([H])S1)C([H])([H])[H])C1=C([H])C(=C(C([H])=C1[H])N1C([H])([H])C([H])([H])C([H])([H])C1([H])[H])S(=O)(=O)N([H])C1=C([H])C([H])=C([H])C([H])=C1OC([H])([H])[H] [H]N(\N=C(/[H])C1=C([H])N(C2=C([H])C([H])=C([H])C([H])=C12)C([H])(C([H])([H])[H])C([H])([H])[H])C(=O)C([H])([H])OC1=C([H])C([H])=C([H])C2=C1N=C([H])C([H])=C2[H] [H]N([H])S(=O)(=O)C1=C([H])C([H])=C(N([H])C(=S)N2C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C2([H])[H])C([H])=C1[H] [H]N(C(=O)C([H])([H])OC1=C([H])C([H])=C(C([H])=C1[H])C(=S)N1C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])[H])C([H])([H])C1([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H] [H]N(C(=S)N([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])C1([H])[H])C1=C([H])C(Cl)=C(OC([H])([H])[H])C([H])=C1[H] [H]N([H])S(=O)(=O)C1=C([H])C([H])=C(N([H])C(=S)N([H])C([H])([H])C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])=C1[H] [H]N(C(=S)C(=O)N([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H] [H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1C([H])([H])C([H])([H])N(C(=S)C2=C([H])C([H])=C(C([H])=C2[H])N(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H] [H]N(C(=S)N([H])C1=C(N2C([H])([H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H])C(Cl)=C([H])C([H])=C1[H])C(=O)C1=C([H])C2=C(OC([H])([H])C([H])([H])O2)C([H])=C1[H] [H]OC(=O)C([H])([H])[C@@]1([H])SC(=NC1=O)N([H])\N=C(/[H])C1=C([H])C(OC([H])([H])C([H])([H])[H])=C(OC([H])([H])C2=C(Cl)C([H])=C(Cl)C([H])=C2[H])C([H])=C1[H] [H]OC1=C(N([H])C2=NC([H])=NC3=C([H])C([H])=C([H])C([H])=C23)C([H])=C(C([H])=C1[H])[N+]([O-])=O [H]N(\N=C(/[H])C1=C([H])C(=C([H])C([H])=C1[H])[N+]([O-])=O)C(=O)C1=C([H])C([H])=C(Br)C([H])=C1[H] [H]N(C(=S)N([H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C1=C([H])C(Cl)=C(OC([H])([H])[H])C([H])=C1[H] [H]N(C(=S)N(C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C1([H])C([H])([H])C([H])([H])N(C(=O)C([H])([H])[H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H] [H]N1C(=S)C(=NC11C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C(F)C([H])=C1[H] [H]N(C(=S)N(C([H])([H])C1=C([H])C([H])=C([H])S1)C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H])C1=C(C([H])=C(C([H])=C1[H])C([H])([H])[H])C([H])([H])[H] [H][N-]S(=O)(=O)C1=C([H])C([H])=C([H])C([H])=C1[H] [H]N([H])C1=NN(C(=O)C2=C([H])C(F)=C([H])C([H])=C2[H])C2=C1C([H])=C1C([H])=C([H])C(OC([H])([H])[H])=C([H])C1=N2 [H]OC(=O)C1=C([H])C(N([H])C(=O)C([H])([H])SC2=NC(=NC3=C2C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2O3)C2=C([H])C([H])=C(F)C([H])=C2[H])=C([H])C([H])=C1[H] [H]N(C(=S)N(C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H])C1([H])C([H])([H])C([H])([H])N(C(=O)OC([H])([H])C([H])([H])[H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C(OC2=C([H])C([H])=C([H])C([H])=C2[H])C([H])=C1[H] [H]N(C(=S)N(C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H])C1([H])C([H])([H])C([H])([H])N(C(=O)OC([H])([H])C([H])([H])[H])C([H])([H])C1([H])[H])C1=C(C([H])=C([H])C(Cl)=C1[H])C([H])([H])[H] [H]N(C(=S)N([H])C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C1=NC2=C([H])C([H])=C([H])C([H])=C2N1[H] [H]N(C(=S)N([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H])C1=C(C([H])=C([H])C(=C1[H])S(=O)(=O)N([H])C1=C([H])C([H])=C(Cl)C([H])=C1[H])N1C([H])([H])C([H])([H])OC([H])([H])C1([H])[H] [H]C1=C(SC(=C1[H])C([H])([H])[H])C(=S)N1C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H] [H]N1C(=S)N([H])[C@@]([H])(C2=C([H])C([H])=C([H])C([H])=C2[H])C2=C1C(=C1SC([H])([H])C([H])([H])S1)C([H])([H])C([H])([H])C2([H])[H] [H]OC1=C([H])C(=O)N([H])C(=N1)N([H])C#N [H]OC1=C([H])C2=C(OC(=O)C([H])=C2C([H])([H])N([H])C2=C([H])C([H])=C([H])C([H])=C2F)C([H])=C1C([H])([H])[H] [H]N(C(=O)C([H])([H])OC1=C([H])C([H])=C(C([H])=C1[H])[N+]([O-])=O)C1=NN=C(S1)C1=C([H])N=C([H])C([H])=C1[H] [H]N(C([H])([H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])C([H])([H])[C@]([H])(N1C(=O)C(=O)N(C([H])([H])C([H])([H])C2=C([H])C(Cl)=C(Cl)C([H])=C2[H])[C@@]([H])(C2=C([H])C([H])=C([H])C([H])=C2[H])C1([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H] [H]N(\N=C(/[H])C1=C([H])C([H])=C(F)C([H])=C1[H])C(=O)C1=C([H])C(=NN1[H])C1=C([H])C2=C(OC([H])([H])O2)C([H])=C1[H] [H]N(C(=O)N1C([H])([H])C([H])([H])N(C(=O)N([H])C2=C([H])C([H])=C([H])C(=C2[H])C(F)(F)F)C([H])([H])C1([H])[H])C1=C([H])C([H])=C([H])C(=C1[H])C(F)(F)F [H]OC(=O)C([H])([H])OC1=C(Br)C([H])=C(\C([H])=C2/SC(=O)N(C2=O)C([H])([H])C(=O)N([H])C2=C([H])C([H])=C(C([H])=C2[H])C([H])([H])[H])C([H])=C1[H] [H]N(C1=C([H])C([H])=C([H])C([H])=C1[H])S(=O)(=O)C1=C([H])C([H])=C([H])C2=NSN=C12 [H]OC1=C(N([H])C(=O)C2=C([H])C(=C([H])C([H])=C2[H])C(=O)N([H])C2=C(O[H])C([H])=C([H])C(=C2[H])[N+]([O-])=O)C([H])=C(C([H])=C1[H])[N+]([O-])=O [H]N(C(=O)C1=C([H])C(=O)C2=C([H])C([H])=C([H])C([H])=C2O1)C1=C([H])C(Cl)=C(OC([H])([H])[H])C([H])=C1[H] [H]OC1=C([H])C([H])=C([H])C([H])=C1C(=O)N([H])\N=C(/[H])C1=C([H])C(OC([H])([H])[H])=C(OC([H])([H])C(=O)N([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])=C1[H] [H]OC(=O)C([H])([H])C([H])([H])C1=C(C2=C(OC1=O)C(=C(OC([H])([H])C1=C([H])C([H])=C([H])C([H])=C1Cl)C([H])=C2[H])C([H])([H])[H])C([H])([H])[H] [H]OC(=O)C(\[H])=C(/[H])C1=C([H])C2=C(C([H])=C1[H])[C@@]([H])(N(C1=C([H])C(OC([H])([H])[H])=C([H])C([H])=C1[H])S2(=O)=O)C([H])([H])C(=O)O[H] [H]N(\N=C(/[H])C1=C([H])C([H])=C(OC([H])([H])C([H])([H])[H])C([H])=C1[H])C(=O)C1=C([H])C2=C(N1[H])C([H])=C([H])C([H])=C2OC([H])([H])[H] [H]OC(=O)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])OC1=C([H])C([H])=C(\C([H])=C2\SC(=O)N(C2=O)C([H])([H])C(=O)OC([H])([H])C([H])([H])[H])C([H])=C1[H] [H]OC(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=O)C([H])([H])C1=C(C2=C([H])C3=C(OC4=C3C([H])([H])C([H])([H])C([H])([H])C4([H])[H])C(=C2OC1=O)C([H])([H])[H])C([H])([H])[H] [H]OC(=O)C([H])([H])C1=C(C2=C(OC1=O)C(=C(OC([H])([H])C1=C([H])C([H])=C([H])C([H])=C1Br)C([H])=C2[H])C([H])([H])[H])C([H])([H])[H] [H]OC(=O)C([H])([H])C1=C(C2=C(OC1=O)C(=C(OC([H])([H])C1=C(Cl)C([H])=C(F)C([H])=C1[H])C([H])=C2[H])C([H])([H])[H])C([H])([H])[H] [H]N([H])S(=O)(=O)C1=C([H])C([H])=C(N([H])C(=S)N2C([H])([H])C([H])([H])C([H])(C([H])([H])C3=C([H])C([H])=C([H])C([H])=C3[H])C([H])([H])C2([H])[H])C([H])=C1[H] [H]N(C(=O)C([H])([H])C([H])([H])N1C(=S)OC2=C([H])C([H])=C([H])C([H])=C12)C1=C([H])C(F)=C(C([H])=C1[H])C([H])([H])[H] [H]\C(=C(\[H])C1=C(C#N)C(SC([H])([H])C2=C([H])C([H])=C([H])C([H])=C2C(=O)OC([H])([H])[H])=NS1)N(C([H])([H])[H])C([H])([H])[H] [H]OC1=C([H])C([H])=C([H])C([H])=C1C(=O)N([H])\N=C1/OC2=C([H])C([H])=C([H])C([H])=C2C([H])=C1C(=O)N([H])[H] [H]N1N(C(=O)\C(=C(\[H])C2=C([H])C([H])=C(C([H])=C2[H])N2C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])C1=O)C1=C([H])C(Br)=C([H])C([H])=C1[H] [H]OC(=O)C1=C([H])C([H])=C(N([H])C(=S)N([H])C(=O)C(\[H])=C(/[H])C2=C([H])C([H])=C(Cl)C([H])=C2[H])C([H])=C1[H] [H]N([H])S(=O)(=O)C1=C([H])C(=C(N([H])\N=C(\C2=C([H])C([H])=C([H])S2)C([H])([H])[H])C([H])=C1[H])[N+]([O-])=O [H]N(\N=C(/[H])C1=C([H])N=C([H])C([H])=C1[H])C(=O)C1=C([H])C([H])=C(N([H])C(=O)C2=C([H])C(Cl)=C([H])C([H])=C2[H])C([H])=C1[H] [H]OC(=O)C1=C([H])N([H])C2=C(C([H])=C(C([H])=C2[H])S(=O)(=O)N([H])[C@@]([H])(C2=C([H])C(OC([H])([H])[H])=C(OC([H])([H])C([H])([H])[H])C([H])=C2[H])C([H])([H])C(=O)OC([H])([H])C([H])([H])[H])C1=O [H]N(C([H])([H])C1=C([H])C([H])=C(F)C([H])=C1[H])S(=O)(=O)C1=C([H])C2=C(OC([H])([H])C([H])([H])N2C(=O)C([H])([H])[H])C([H])=C1[H] [H]N(\N=C(/[H])C1=C([H])C(Br)=C([H])C([H])=C1[H])C(=O)C1=C([H])C([H])=C(C([H])=C1[H])N1C(=O)C([H])([H])C([H])([H])C1([H])[H] [H]N(C(=O)C1=C([H])C2=C(N=C(S2)N2C([H])([H])C([H])([H])OC([H])([H])C2([H])[H])C([H])=C1[H])C1=C(Cl)C([H])=C(C([H])=C1[H])C([H])([H])[H] [H]OC(=O)C([H])([H])N1C(=S)S\C(=C(/[H])C2=C([H])C(OC([H])([H])[H])=C(OC([H])([H])C(=O)N([H])C3=C([H])C(=C(C([H])=C3[H])C([H])([H])[H])C([H])([H])[H])C([H])=C2[H])C1=O [H]OC(=O)C1=C(N([H])C(=O)[C@]([H])(N2C(=S)S\C(=C(/[H])C3=C([H])C([H])=C([H])S3)C2=O)C([H])([H])[H])C([H])=C([H])C(O[H])=C1[H] [H]N(C1=C([H])C(=C([H])C([H])=C1[H])N1N=NN=C1[H])S(=O)(=O)C1=C([H])C([H])=C(C([H])=C1[H])C(=O)C([H])([H])[H] [H]OC1=C([H])C([H])=C([H])C([H])=C1C(=O)N([H])\N=C(\C1=C([H])C([H])=C(N([H])C(=O)C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])=C1[H])C([H])([H])[H] [H]OC1=C([H])C(=C([H])C(O[H])=C1[H])C(=O)N([H])\N=C(/[H])C1=C([H])OC([H])=C1[H] [H]N(\N=C(/[H])C1=C([H])C([H])=C(O1)C1=C(Cl)C([H])=C(C([H])=C1[H])[N+]([O-])=O)C(=O)C1=NN([H])C(=C1[H])C([H])([H])[H] [H]N([H])S(=O)(=O)C1=C([H])C([H])=C(N([H])C(=O)C([H])([H])OC2=C([H])C3=C(C([H])=C2[H])C(=C([H])C(=O)O3)C([H])([H])C([H])([H])C([H])([H])[H])C([H])=C1[H] [H]N(C(=O)C1=C([H])C([H])=C(Br)O1)C1=C([H])C([H])=C(C([H])=C1[H])C1=NN=C(OC([H])([H])[H])C([H])=C1[H] [H]N(C(=O)C([H])([H])N(C(=O)C([H])([H])C1=C([H])C2=C(C([H])=C1[H])C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C([H])([H])C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1OC([H])([H])[H] [H]N(C(=O)[C@@]([H])(SC([H])([H])C1=NC2=C(C(=C(S2)C([H])([H])[H])C([H])([H])[H])C(=O)N1[H])C([H])([H])[H])C1=NC([H])=C(Cl)C([H])=C1[H] [H]OC(=O)[C@]([H])(S[H])[C@]([H])(S[H])C(=O)O[H] [H]N([H])C1=C(C(=O)C([H])([H])OC(=O)C2=C([H])C(=C(C([H])=C2[H])C([H])([H])[H])S(=O)(=O)N(C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])[H])C(=O)N(C(=O)N1C([H])([H])[H])C([H])([H])[H] [H]N(C1=NN2C(S1)=NC1=C([H])C([H])=C([H])C([H])=C1C2=O)C1=C([H])C(OC([H])([H])[H])=C([H])C([H])=C1[H] [H]OC(=O)C1=C([H])C([H])=C([H])C([H])=C1N([H])S(=O)(=O)C1=C([H])C(=C(N([H])\N=C(/[H])C2=C([H])C([H])=C(SC([H])([H])[H])C([H])=C2[H])C([H])=C1[H])[N+]([O-])=O [H]N1C([H])=NC(=S)C2=C1N(C([H])=N2)C1=C([H])C([H])=C(Cl)C([H])=C1[H] [H]OC1=C2C([H])=C([H])C(N([H])[H])=C([H])C2=C([H])C(=C1[H])S(=O)(=O)O[H] OC1=CC(=CC2=CC=C(NC3=CC=CC=C3)C=C12)S(O)(=O)=O [H]N(N([H])C(=O)N([H])N([H])C(\[H])=C1/C([H])=C([H])C([H])=C([H])C1=O)C(\[H])=C1/C([H])=C([H])C([H])=C([H])C1=O [H]N(N([H])C(=O)C1=C([H])C(=C([H])C([H])=C1[H])[N+]([O-])=O)C(\[H])=C1/C([H])=C([H])C([H])=C([H])C1=O [H]N(\N=C(\C1=C([H])C([H])=C([H])C(=N1)C([H])([H])[H])C([H])([H])[H])C(=S)N1C([H])([H])[C@@]2([H])C([H])([H])C([H])([H])[C@]([H])(C([H])([H])C2([H])[H])C1([H])[H] [H]OC(=O)C1=C(O[H])C(=O)C([H])=C([H])C([H])=C1C([H])([H])C(=O)O[H] [H]OC1=C(O[H])C(=C(O[H])C(=O)\C1=C1\C(=O)C(=O)C(=C(O[H])C1=O)C([H])([H])[H])C([H])([H])[H] [H]N([H])N=C1C(Cl)=C(Cl)C(Cl)=C1Cl [H]N(C(=O)C1=C([H])N([H])C(=O)C([H])=C1[H])C1=C(C([H])=C([H])C(=C1[H])S(=O)(=O)N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])[H] [H]N(N([H])C(=O)C1=C([H])C2=C(OC([H])([H])O2)C([H])=C1[H])C(\[H])=C1/C([H])=C(Cl)C([H])=C(OC([H])([H])[H])C1=O [H]N(C(=O)C1=C([H])C([H])=C(C([H])=C1[H])[N+]([O-])=O)C1=C([H])C([H])=C([H])C2=C1C(=O)N([H])N([H])C2=O [H]OC(=O)C([H])([H])OC1=C(OC([H])([H])[H])C([H])=C(\C([H])=C2/SC3=NC(=C(C(=O)OC([H])([H])C([H])([H])[H])[C@@]([H])(N3C2=O)C2=C(Cl)C([H])=C([H])C([H])=C2[H])C([H])([H])[H])C([H])=C1C([H])([H])[H] [H]OC(=O)C([H])([H])OC1=C([H])C([H])=C(\C([H])=C2/SC3=NC(=C(C(=O)OC([H])([H])C([H])([H])[H])[C@@]([H])(N3C2=O)C2=C([H])C(OC([H])([H])[H])=C([H])C([H])=C2[H])C([H])([H])[H])C([H])=C1[H] [H]OC([H])([H])[C@]1([H])OC(=O)\C(=C(/N([H])C([H])([H])C2=C([H])C(=C([H])C([H])=C2[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C1=O [H]OC([H])([H])[C@]1([H])OC(=O)\C(=C(/N([H])C([H])([H])C2=C([H])C(Cl)=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C1=O [H]OC([H])([H])[C@]1([H])OC(=O)\C(=C(/N([H])C([H])([H])C2=C([H])C(F)=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C1=O [H]OC([H])([H])[C@]1([H])OC(=O)\C(=C(/N([H])C([H])([H])C2=C([H])C(OC([H])([H])[H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C1=O [H]OC([H])([H])[C@]1([H])OC(=O)\C(=C(/N([H])C([H])([H])C2=C([H])C(=C([H])C([H])=C2[H])N(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C1=O [H]OC([H])([H])[C@]1([H])OC(=O)\C(=C(/N([H])C([H])([H])C2=C([H])C([H])=C(Cl)C([H])=C2[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C1=O [H]OC([H])([H])[C@]1([H])OC(=O)\C(=C(/N([H])C([H])([H])C2=C([H])C([H])=C(F)C([H])=C2[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C1=O [H]OC1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N([H])C(=C1/C(=O)O[C@@]([H])(C1=O)C([H])([H])O[H])\C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H] [H]OC([H])([H])[C@@]1([H])OC(=O)\C(=C(/N([H])C([H])([H])C2=C([H])C([H])=C(OC([H])([H])[H])C([H])=C2[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C1=O [H]OC([H])([H])[C@@]1([H])OC(=O)\C(=C(/N([H])C([H])([H])C2=C(C([H])=C([H])C([H])=C2[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C1=O [H]OC([H])([H])[C@@]1([H])OC(=O)\C(=C(/N([H])C([H])([H])C2=C(F)C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C1=O [H]OC([H])([H])[C@@]1([H])OC(=O)\C(=C(/N([H])C([H])([H])C2=C(OC([H])([H])[H])C([H])=C([H])C([H])=C2[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C1=O [H]OC([H])([H])[C@]1([H])OC(=O)\C(=C(/N([H])C([H])([H])C2=C(C([H])=C([H])C([H])=C2[H])N(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C1=O [H]OC([H])([H])[C@@]1([H])OC(=O)\C(=C(/N([H])C([H])([H])C2=C([H])C([H])=C(C([H])=C2[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C1=O O=C(NC1=CC=C(C=C1)S(=O)(=O)NC1=NC=CS1)C1=CC=C(\C=C\C(=O)C2=CC=C(C=C2)C#N)C=C1 CC1=CC=C(C=C1)C(=O)\C=C\C1=CC=C(C=C1)C(=O)NC1=CC=C(C=C1)S(=O)(=O)NC1=NC=CS1 OC(=O)C1=CC2=C(OC(=C2CCC2=CC=C(OC3=CC=CC=C3)C=C2)C2=CC=CC=C2)C=C1O OC(=O)C1=CC2=C(OC(=C2CCC2=CC=C(OC(F)(F)F)C=C2)C2=CC=CC=C2)C=C1O OC(=O)C1=CC2=C(OC(=C2CCC2=CC=CC(=C2)C(F)(F)F)C2=CC=CC=C2)C=C1O OC(=O)C1=CC2=C(OC(=C2\C=C/C2=CC=C(OC(F)(F)F)C=C2)C2=CC=CC=C2)C=C1O OC(=O)C1=CC2=C(OC(=C2\C=C/C2=CC(F)=CC(F)=C2)C2=CC=CC=C2)C=C1O OC(=O)C1=CC2=C(OC(=C2C#CC2=CC=C(OC3=CC=CC=C3)C=C2)C2=CC=CC=C2)C=C1O OC(=O)C1=CC2=C(OC(=C2C#CC2=CC=C(OC(F)(F)F)C=C2)C2=CC=CC=C2)C=C1O OC(=O)C1=CC2=C(OC(=C2C#CC2=CC=CC(=C2)C(F)(F)F)C2=CC=CC=C2)C=C1O OC(=O)C1=CC2=C(OC(=C2C#CC2=CC(F)=CC(F)=C2)C2=CC=CC=C2)C=C1O OC(=O)C1=CC2=C(OC(=C2C#CC2=CC=C(F)C=C2F)C2=CC=CC=C2)C=C1O OC(=O)C1=CC2=C(OC(=C2C#CC2=CC=CC(F)=C2)C2=CC=CC=C2)C=C1O OC(=O)C1=CC2=C(OC(=C2C#CC2=CC=CC=C2)C2=CC=CC=C2)C=C1O