[H]N1C(=O)[C@]2([H])N(C(=O)[C@@]([H])(N([H])C(=O)[C@]([H])(N([H])C(=O)[C@]1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C(=O)C(F)(F)F)C([H])([H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])[C@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C2([H])[H] [H]N1C(=O)[C@]2([H])N(C(=O)[C@@]([H])(N([H])C(=O)[C@]([H])(N([H])C(=O)[C@]1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])SC([H])([H])C(=O)C(F)(F)F)C([H])([H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])[C@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C2([H])[H] [H]ON([H])C(=O)C(\[H])=C(/[H])\C(=C(/[H])[C@]([H])(C(=O)C1=C([H])C([H])=C(C([H])=C1[H])N(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])\C([H])([H])[H] [H]ON([H])C(=O)C(\[H])=C(/[H])C1=C([H])C([H])=C2C(=O)N(C(=O)C2=C1[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H] [H]ON([H])C(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@]([H])(N([H])C(=O)C([H])([H])C1=C(N([H])C2=C1C([H])=C(OC([H])([H])[H])C([H])=C2[H])C([H])([H])[H])C(=O)N([H])C([H])([H])C([H])([H])C1=C(N([H])C2=C1C([H])=C([H])C([H])=C2[H])C1=C([H])C([H])=C([H])C([H])=C1[H] [H]SC([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@]([H])(N([H])C(=O)OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C(=O)N([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H] [H]ON([H])C(=O)C(\[H])=C(/[H])C1=C([H])C2=C(C([H])=C1[H])C([H])([H])N(C2=O)C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H] [H]C([H])=C([H])C([H])([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])[N+](=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])[N+](=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])=C([H])[H] [H]ON([H])C(=O)C(\[H])=C(/[H])C1=C([H])C2=C(C([H])=C1[H])C([H])([H])N(C2=O)C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H] [H]ON([H])C(=O)C(\[H])=C(/[H])C1=C([H])C2=C(C([H])=C1[H])C([H])([H])N(C2=O)C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C([H])N=C1[H] [H]ON([H])C(=O)C(\[H])=C(/[H])C1=C([H])C2=C(C([H])=C1[H])C([H])([H])N(C2=O)C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H] [H]ON([H])C(=O)C(\[H])=C(/[H])C1=C([H])C2=C(C([H])=C1[H])C([H])([H])N(C2=O)C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=NC([H])=C1[H] [H]OC([H])([H])[C@]1([H])N([H])C(=O)C(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@]2([H])N(C1=O)C([H])([H])C([H])([H])C2([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])SSC1=NC([H])=C([H])C([H])=C1[H])(C([H])([H])[H])C([H])([H])[H] [H]N1C(=O)[C@]2([H])N(C(=O)[C@@]([H])(N([H])C(=O)C(N([H])C(=O)[C@]1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])SSC1=NC([H])=C([H])C([H])=C1[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])OC([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C2([H])[H] [H]N1C(=O)[C@]2([H])N(C(=O)[C@@]([H])(N([H])C(=O)[C@@]3(N([H])C(=O)[C@]1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])SSC1=NC([H])=C([H])C([H])=C1[H])C1=C(C([H])=C([H])C([H])=C1[H])C([H])([H])C3([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C2([H])[H] [H]N1C(=O)[C@]2([H])N(C([H])([H])C3=C(C([H])=C([H])C([H])=C3[H])C2([H])[H])C([H])([H])[C@@]([H])(N([H])C(=O)C(N([H])C(=O)[C@]1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])SSC1=NC([H])=C([H])C([H])=C1[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H] [H]N1C(=O)[C@]2([H])N(C(=O)[C@@]([H])(N([H])C(=O)C(N([H])C(=O)[C@]1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])SSC1=NC([H])=C([H])C([H])=C1[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C2([H])[H] [H]N1C(=O)[C@]2([H])N(C(=O)[C@@]([H])(N([H])C(=O)C(N([H])C(=O)[C@]1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])SSC1=NC([H])=C([H])C([H])=C1[H])(C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C2([H])[H] [H]N1C(=O)[C@]2([H])N(C(=O)[C@@]([H])(N([H])C(=O)C(N([H])C(=O)[C@]1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])SSC1=NC([H])=C([H])C([H])=C1[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C2([H])[H] [H]N1C(=O)[C@]2([H])N(C(=O)[C@@]([H])(N([H])C(=O)[C@](N([H])C(=O)[C@]1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])SSC1=NC([H])=C([H])C([H])=C1[H])(C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H])C([H])([H])C([H])([H])C2([H])[H] [H]N1C(=O)[C@]2([H])N(C(=O)[C@@]([H])(N([H])C(=O)C(N([H])C(=O)[C@]1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])SSC1=NC([H])=C([H])C([H])=C1[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C2([H])[H] [H]N1C(=O)[C@]2([H])N(C(=O)[C@@]([H])(N([H])C(=O)C(N([H])C(=O)[C@]1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])SSC1=NC([H])=C([H])C([H])=C1[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C2([H])[H] [H]N1C(=O)[C@]2([H])N(C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@]1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C(=O)C([H])([H])C([H])([H])[H])C([H])([H])C1=C([H])N(OC([H])([H])[H])C3=C1C([H])=C([H])C([H])=C3[H])[C@@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C2([H])[H] [H]ON([H])C(=O)C(\[H])=C(/[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N(C([H])([H])C([H])([H])O[H])C([H])([H])C([H])([H])C1=C([H])N([H])C2=C([H])C([H])=C([H])C([H])=C12 [H]OC(=O)[C@@]([H])(N([H])C(=O)[C@]1([H])N(C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])[H])C([H])([H])C2=C([H])N(OC([H])([H])[H])C3=C2C([H])=C([H])C([H])=C3[H])[C@]([H])(C([H])([H])[H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C(=O)C([H])([H])C([H])([H])[H] [H]ON([H])C(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C(=O)N([H])C1=C([H])C([H])=C([H])C([H])=C1[H] [H]N1C(=O)[C@]2([H])N(C(=O)[C@@]([H])(N([H])C(=O)[C@]3(N([H])C(=O)[C@]1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])SSC1=NC([H])=C([H])C([H])=C1[H])C([H])([H])C1=C(C([H])=C([H])C([H])=C1[H])C3([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C2([H])[H] [H]ON([H])C(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=O)C(\[H])=C(\C(\[H])=C(/[H])C1=C([H])C([H])=C([H])C([H])=C1[H])/C([H])([H])[H] [H]ON([H])C(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=O)C(\[H])=C(/[H])C1=C([H])C([H])=C2C([H])=C([H])C([H])=NC2=C1[H] [H]ON([H])C(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=O)C([H])=C1C2=C(C([H])=C([H])C([H])=C2[H])C2=C1C([H])=C([H])C([H])=C2[H] [H]ON([H])C(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=O)C(\[H])=C(/[H])C1=C([H])C([H])=C(Cl)C([H])=C1F [H]ON([H])C(=O)C(\[H])=C(/[H])C1=C([H])C([H])=C(O1)C(\[H])=C(/[H])C(=O)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H] [H]ON([H])C(=O)C1=C([H])C([H])=C([H])C([H])=C1N([H])C(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C(=O)N([H])C1=C([H])C([H])=C([H])C([H])=C1[H] [H]ON([H])C(=O)C(\[H])=C(/[H])C1=C([H])C([H])=C(O1)C(\[H])=C(/[H])C(=O)C1=C([H])C([H])=C(F)C([H])=C1[H] [H]ON([H])C(=O)C(\[H])=C(/[H])C1=C([H])C([H])=C(O1)C(\[H])=C(/[H])C(=O)C1=C(Cl)C([H])=C(Cl)C([H])=C1[H] [H]ON([H])C(=O)C(\[H])=C(/[H])C1=C([H])C([H])=C(O1)C(\[H])=C(/[H])C(=O)C1=C(Cl)C([H])=C([H])C(Cl)=C1[H] [H]ON([H])C(=O)C(\[H])=C(/[H])C1=C([H])C([H])=C(O1)C(\[H])=C(/[H])C(=O)C1=C([H])C([H])=C2C([H])=C([H])C([H])=C([H])C2=C1[H] [H]ON([H])C(=O)C(\[H])=C(/[H])C1=C([H])C([H])=C(O1)C(\[H])=C(/[H])C(=O)C1=C([H])C([H])=C2C([H])=C(OC([H])([H])[H])C([H])=C([H])C2=C1[H] [H]ON([H])C(=O)C(\[H])=C(/[H])C1=C([H])C([H])=C(O1)C(\[H])=C(/[H])C(=O)C1=C([H])C([H])=C(Cl)C([H])=C1[H] [H]ON([H])C(=O)C(\[H])=C(/[H])C1=C([H])C([H])=C(O1)C(\[H])=C(/[H])C(=O)C1=C([H])C([H])=C(C([H])=C1[H])C([H])(C([H])([H])[H])C([H])([H])[H] [H]C1=C(SC(=N1)C1=C([H])C([H])=C(S1)C(=O)C(F)(F)F)C1=C([H])C([H])=C([H])C([H])=C1[H] [H]N(C(=O)C1=C([H])C([H])=C(S1)C(=O)C(F)(F)F)C([H])([H])C([H])([H])[H] [H]C1=NN=C(O1)C1=C([H])C([H])=C(OC([H])([H])C2=NOC(=N2)C2=C([H])C([H])=C(S2)C(=O)C(F)(F)F)C([H])=C1[H] [H]C1=C([H])C([H])=C(S1)C([H])([H])C1=NOC(=N1)C1=C([H])C([H])=C(S1)C(=O)C(F)(F)F [H]C1=C(SC(=C1[H])C1=NN=C(O1)C1=C([H])C([H])=C([H])C([H])=C1[H])C(=O)C(F)(F)F [H]C1=C([H])C([H])=C(S1)C1=NN=C(O1)C1=C([H])C([H])=C(S1)C(=O)C(F)(F)F [H]C1=C(SC(=C1[H])C(=O)C(F)(F)F)C(=O)N(C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H] [H]C1=C(SC(=C1[H])C1=NC(=NO1)C1=C([H])C([H])=NC([H])=C1[H])C(=O)C(F)(F)F [H]C1=C(SC(=C1[H])C1=NC(=NO1)C1=C([H])C([H])=C(C([H])=C1[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C(=O)C(F)(F)F [H]C1=C(SC(=C1[H])C1=NC(=NO1)C1=C([H])C([H])=C([H])C([H])=C1[H])C(=O)C(F)(F)F [H]C1=C(SC(=C1[H])C1=NC(=NO1)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H])C(=O)C(F)(F)F [H]C1=C(SC(=C1[H])C1=NC(=NO1)C1=C(F)C([H])=C(F)C([H])=C1[H])C(=O)C(F)(F)F [H]N(C(=O)C1=C([H])C([H])=C(S1)C(=O)C(F)(F)F)[C@]([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H] [H]C1=C(SC(=C1[H])C1=NC(=NO1)C1=C([H])C([H])=C(C([H])=C1[H])C(F)(F)F)C(=O)C(F)(F)F [H]C1=C(SC(=C1[H])C1=NC(=NO1)C1=C([H])C([H])=C(F)C([H])=C1[H])C(=O)C(F)(F)F [H]C1=C(SC(=C1[H])C1=NC(=NO1)C1=C(Cl)C([H])=C(Cl)C([H])=C1[H])C(=O)C(F)(F)F [H]N(C(=O)C1=C([H])C([H])=C(S1)C(=O)C(F)(F)F)C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H] [H]C1=C(SC(=C1[H])C1=NN=C(O1)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H])C(=O)C(F)(F)F [H]C1=C(SC(=C1[H])C1=NC(=NO1)C1=C([H])C(=C([H])C([H])=C1[H])C([H])([H])[H])C(=O)C(F)(F)F [H]C1=C(SC(=C1[H])C1=NC(=NO1)C1=C([H])C(=C([H])C([H])=C1[H])C(F)(F)F)C(=O)C(F)(F)F [H]C1=C(SC(=C1[H])C1=NC(=NO1)C([H])([H])N1C(=O)C([H])([H])OC2=C1C([H])=C([H])C([H])=C2[H])C(=O)C(F)(F)F [H]C1=C(SC(=C1[H])C1=NC(=NO1)C([H])([H])S(=O)(=O)C([H])([H])[H])C(=O)C(F)(F)F [H]C1=C(SC(=C1[H])C1=NC(=NO1)C([H])([H])S(=O)(=O)C([H])([H])C([H])([H])C([H])([H])[H])C(=O)C(F)(F)F [H]C1=C([H])C([H])=C(S1)S(=O)(=O)C([H])([H])C1=NOC(=N1)C1=C([H])C([H])=C(S1)C(=O)C(F)(F)F [H]C1=C(SC(=C1[H])C1=NC(=NO1)C([H])([H])C(=O)N1C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C(=O)C(F)(F)F [H]C1=C(SC(=C1[H])C1=NC(=NO1)C([H])([H])S(=O)(=O)C([H])([H])C1=C([H])C([H])=C(F)C([H])=C1[H])C(=O)C(F)(F)F [H]C1=C(SC(=C1[H])C1=NC(=NO1)C1=C([H])C([H])=C([H])N=C1[H])C(=O)C(F)(F)F [H]C1=C(SC(=C1[H])C1=NC(=NO1)C([H])([H])[H])C(=O)C(F)(F)F [H]C1=C(SC(=C1[H])C1=NC(=NO1)C1=C([H])C([H])=C([H])C([H])=N1)C(=O)C(F)(F)F [H]C1=C([H])C([H])=C(S1)C1=NOC(=N1)C1=C([H])C([H])=C(S1)C(=O)C(F)(F)F [H]N(C(=O)C([H])([H])C1=C(N([H])C2=C([H])C([H])=C(OC([H])([H])[H])C([H])=C12)C([H])([H])[H])[C@]([H])(C1=NC([H])=C(N1[H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C(=O)C([H])([H])[H] [H]N(C(=O)C1([H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H])[C@]([H])(C1=NC([H])=C(N1[H])C1=C([H])C2=C([H])C([H])=C([H])C([H])=C2C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C(=O)C([H])([H])[H] ONC(=O)\C=C\C1=CC=C(\C=N\OCC2=CC=C(C=C2)N(O)=O)C=C1 [H]ON([H])C(=O)C(\[H])=C(/[H])C1=C([H])C2=C(C([H])=C1[H])N(C(=N2)C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])C1([H])[H] [H]ON([H])C(=O)C(\[H])=C(/[H])C1=C([H])C([H])=C(C(F)=C1[H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])[C@]([H])(C2=C(N([H])C3=C2C([H])=C([H])C([H])=C3[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C1([H])[H] [H]ON([H])C(=O)C1=C([H])N=C(N=C1[H])N1C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])S(=O)(=O)C1=C([H])C2=C(C([H])=C([H])C([H])=C2[H])C([H])=C1[H] [H]ON([H])C(=O)C1=C([H])N=C(N=C1[H])N1C([H])([H])C([H])([H])N(C([H])([H])C1([H])[H])[C@@]([H])(C(\[H])=C(/[H])C1=C([H])C([H])=C(F)C([H])=C1[H])C([H])([H])O[H] [H]ON([H])C(=O)C([H])(C1=C([H])C([H])=C([H])C(F)=C1[H])C1=C([H])C([H])=C([H])C(F)=C1[H] [H]ON([H])C(=O)C([H])(C1=C([H])C([H])=C(F)C([H])=C1[H])C1=C([H])C([H])=C(F)C([H])=C1[H] [H]ON([H])C(=O)C1([H])C2=C(C([H])=C([H])C([H])=C2[H])N(C2=C1C([H])=C([H])C([H])=C2[H])C([H])([H])[H] [H]ON([H])C(=O)C1([H])C2=C(OC3=C1C([H])=C([H])C([H])=C3[H])C([H])=C([H])C([H])=C2[H] [H]ON([H])C(=O)C1([H])C2=C(C([H])=C([H])C([H])=C2[H])C([H])([H])C2=C1C([H])=C([H])C([H])=C2[H] [H]ON([H])C(=O)C(C1=C([H])C([H])=C([H])C([H])=C1[H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])[H] [H]ON([H])C(=O)C([H])(C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H] [H]ON([H])C(=O)C([H])(C1=C([H])C([H])=C(Cl)C([H])=C1[H])C1=C([H])C([H])=C(Cl)C([H])=C1[H] [H]ON([H])C(=O)C([H])(C1=C([H])C([H])=C2OC([H])([H])C([H])([H])C2=C1[H])C1=C([H])C([H])=C2OC([H])([H])C([H])([H])C2=C1[H] [H]ON([H])C(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=O)N([H])C(=O)C1=C([H])C([H])=C([H])C([H])=C1[H] [H]ON([H])C(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=O)N([H])C(=O)C1=C([H])C([H])=C(Br)C([H])=C1[H] [H]ON([H])C(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])(C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H] [H]ON([H])C(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])(C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2OC([H])([H])[H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2OC([H])([H])[H] [H]ON([H])C(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])(C1=C([H])N([H])C2=C1C([H])=C(C([H])=C2[H])[N+]([O-])=O)C1=C([H])N([H])C2=C1C([H])=C(C([H])=C2[H])[N+]([O-])=O [H]ON([H])C(=O)C(\[H])=C(/[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])(C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H])C1=C([H])N([H])C2=C1C([H])=C([H])C([H])=C2[H] [H]N1C(=O)C([H])([H])[C@]([H])(OC(=O)[C@@]([H])(N([H])C(=O)C2=C([H])SC(=N2)C2=C([H])SC(=N2)C1([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])C(\[H])=C(/[H])C([H])([H])C([H])([H])SC(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H] [H]N1C(=O)C([H])([H])[C@]([H])(OC(=O)[C@@]([H])(N([H])C(=O)[C@]2(N=C(SC2([H])[H])C2=C([H])SC(=N2)C1([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])(C([H])([H])[H])C([H])([H])[H])C(\[H])=C(/[H])C([H])([H])C([H])([H])SC(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H] [H]N1C(=O)C([H])([H])[C@]([H])(OC(=O)[C@@]([H])(N([H])C(=O)[C@]2(N=C(SC2([H])[H])C2=C([H])SC(=N2)C1([H])[H])C([H])([H])C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])C(\[H])=C(/[H])C([H])([H])C([H])([H])SC(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H] [H]N1C(=O)C([H])([H])[C@]([H])(OC(=O)[C@@]([H])(N([H])C(=O)[C@@]2([H])N=C(SC2([H])[H])C2=C([H])SC(=N2)C1([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])C(\[H])=C(/[H])C([H])([H])C([H])([H])SC(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H] [H]N1C(=O)C([H])([H])[C@]([H])(OC(=O)[C@@]([H])(N([H])C(=O)[C@]2(N=C(SC2([H])[H])C2=C([H])SC(=N2)C1([H])[H])C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])C(\[H])=C(/[H])C([H])([H])C([H])([H])SC(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H] [H]ON([H])C(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])OC1=C(OC([H])([H])[H])C([H])=C2N=C([H])N=C(N([H])C3=C([H])C(C#C[H])=C([H])C([H])=C3[H])C2=C1[H] [H]ON([H])C(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@]1([H])N([H])C(=O)[C@]2([H])N(C(=O)[C@@]3([H])N([H])C(=O)[C@]([H])(N([H])C1=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C3([H])[H])C([H])([H])C([H])([H])C2([H])[H] [H]ON([H])C(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N1C(=O)C2=C([H])C([H])=C([H])C3=C([H])C([H])=C([H])C(C1=O)=C23 [H]ON([H])C(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@@]([H])(OC([H])([H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])C(=O)N([H])C1=C([H])C([H])=C([H])C([H])=C1[H] [H]ON([H])C(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@]1([H])OC([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])OC2=C(N([H])C1=O)C([H])=C([H])C([H])=C2[H] [H]ON([H])C(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@]1([H])OC([H])([H])\C([H])=C([H])/C2=C([H])C(OC([H])([H])[H])=C([H])C(=C2[H])C([H])([H])OC2=C([H])C([H])=C([H])C([H])=C2N([H])C1=O [H]ON([H])C(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])OC([H])([H])C([H])([H])C([H])([H])C2=C([H])C(OC([H])([H])[H])=C([H])C(=C2[H])C([H])([H])OC2=C([H])C([H])=C([H])C([H])=C2N([H])C1=O [H]C1=C(N2C(=N1)C([H])([H])N(C(=O)C1=C([H])C([H])=C(S1)C(=O)C(F)(F)F)C([H])([H])C2([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H] [H]SC([H])([H])C([H])([H])C(\[H])=C(/[H])[C@@]1([H])OC(=O)[C@@]([H])(N([H])C(=O)\C(N([H])C(=O)[C@]([H])(N([H])C(=O)[C@]([H])(C([H])([H])C(=O)C1([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])S[H])=C(/[H])C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H] [H]SC([H])([H])C([H])([H])C(\[H])=C(/[H])[C@@]1([H])OC(=O)[C@@]([H])(N([H])C(=O)\C(N([H])C(=O)[C@]([H])(N([H])C(=O)[C@]([H])(N([H])C(=O)C1([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])S[H])=C(\[H])C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H] [H]ON([H])C(=O)C(\[H])=C(/[H])C1=C([H])C2=C(C([H])=C1[H])N(C(=N2)C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H] [H]ON([H])C(=O)C(\[H])=C(/[H])C1=C([H])C([H])=C2N(C(=NC2=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H] [H]ON([H])C(=O)C(\[H])=C(/[H])C1=C([H])C([H])=C2N(C(=NC2=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])N([H])C([H])(C([H])([H])[H])C([H])([H])[H] [H]ON([H])C(=O)C(\[H])=C(/[H])C1=C([H])C([H])=C2N(C(=NC2=C1[H])C([H])([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H] [H]ON([H])C(=O)C(\[H])=C(/[H])C1=C([H])C([H])=C2N(C(=NC2=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])N([H])C([H])([H])C([H])([H])[H] [H]ON([H])C(=O)C(\[H])=C(/[H])C1=C([H])C([H])=C2N(C(=NC2=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H] [H]ON([H])C(=O)C(\[H])=C(/[H])C1=C([H])C([H])=C2N(C(=NC2=C1[H])C([H])([H])C([H])([H])C(\[H])=C(\[H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])N([H])C([H])([H])C([H])([H])[H] [H]ON([H])C(=O)C(\[H])=C(/[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N([H])C([H])([H])C([H])([H])C1=C(N([H])C2=C([H])C([H])=C([H])C([H])=C12)C([H])([H])[H] [H]ON([H])C(=O)C(\[H])=C(/[H])C1=C([H])C([H])=C([H])C(=C1[H])S(=O)(=O)N([H])C1=C([H])C([H])=C([H])C([H])=C1[H] [H]ON([H])C(=O)C(\[H])=C(/[H])C1=C([H])C2=C(C([H])=C1[H])N(C(=N2)C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H] [H]ON([H])C(=O)C(\[H])=C(/[H])C1=C([H])C([H])=C2N(C(=NC2=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])N([H])C([H])(C([H])([H])[H])C([H])([H])[H] [H]ON([H])C(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=O)C1=NOC(=C1[H])C1=C([H])C([H])=C(N([H])C(=O)C2=C([H])C(=C([H])C(N=[N+]=[N-])=C2[H])C([H])([H])N=[N+]=[N-])C([H])=C1[H] [H]ON([H])C(=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C(=O)N([H])C1=C([H])N(N=C1[H])C([H])([H])C1=C([H])C(=C([H])C(N=[N+]=[N-])=C1[H])C([H])([H])N=[N+]=[N-] [H]ON([H])C(=O)C(\[H])=C(/[H])C1=C([H])C2=C(OC3(C([H])([H])C2=O)C([H])([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C3([H])[H])C([H])=C1[H] [H]ON([H])C(=O)C(\[H])=C(/[H])C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)N([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H] [H]N1C(=O)[C@]2([H])N(C(=O)[C@@]([H])(N([H])C(=O)[C@@]([H])(N([H])C(=O)[C@]1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C(=O)[C@@]1([H])OC1([H])[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C2([H])[H] [H]ON([H])C(=O)C(\[H])=C(/[H])C1=C([H])C([H])=C(N([H])S(=O)(=O)C2=C([H])C([H])=C(OC([H])([H])[H])C([H])=C2[H])C([H])=C1[H] [H]ON([H])C(=O)C([H])([H])C([H])([H])C1=C([H])C([H])=C(N([H])S(=O)(=O)C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])=C1[H] [H]ON([H])C(=O)C(\[H])=C(/[H])C1=C([H])C([H])=C(N([H])S(=O)(=O)C2=C([H])C([H])=C(OC([H])([H])[H])C(OC([H])([H])[H])=C2[H])C([H])=C1[H] [H]ON([H])C(=O)C(\[H])=C(/[H])C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)N([H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H] [H]ON([H])C(=O)C(\[H])=C(/[H])C1=C([H])C([H])=C(N([H])S(=O)(=O)C2=C([H])C([H])=C(C([H])=C2[H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])=C1[H] [H]ON([H])C(=O)C(\[H])=C(/[H])C1=C([H])C([H])=C(N([H])S(=O)(=O)C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])=C1[H] [H]ON([H])C(=O)C1=C([H])C([H])=C(N([H])S(=O)(=O)C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])=C1[H] [H]ON([H])C(=O)C(\[H])=C(/[H])C1=C([H])C([H])=C(C([H])=C1[H])S(=O)(=O)N([H])C1=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C([H])=C1[H] [H]OC(=O)C([H])([H])C([H])([H])C(\[H])=C(\[H])C([H])([H])[C@@]1([H])N([H])C(=O)[C@]([H])(N([H])C(=O)[C@]([H])(N([H])C(=O)[C@]([H])(N([H])C(=O)[C@@]1([H])C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H] [H]OC(=O)C([H])([H])C([H])([H])C(\[H])=C(\[H])C([H])([H])[C@@]1([H])N([H])C(=O)[C@]([H])(N([H])C(=O)[C@]([H])(N([H])C(=O)[C@]([H])(N([H])C(=O)[C@@]1([H])C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(O[H])C([H])=C1[H] [H]OC1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[C@@]1([H])N([H])C(=O)[C@]([H])(N([H])C(=O)[C@]([H])(N([H])C(=O)[C@@]([H])(C([H])([H])[H])[C@]([H])(N([H])C1=O)C([H])([H])C(\[H])=C(\[H])C([H])([H])C([H])([H])C(=O)N([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H] [H]N1C(=O)[C@]2([H])N(C(=O)[C@@]([H])(N([H])C(=O)C(N([H])C(=O)[C@]1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])SC(=O)C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])OC([H])([H])C([H])([H])SC(=O)C([H])([H])[H])C([H])([H])C([H])([H])C2([H])[H] [H]N1C(=O)[C@]2([H])N(C(=O)[C@@]([H])(N([H])C(=O)C(N([H])C(=O)[C@]1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])SC(=O)C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])SC(=O)C([H])([H])[H])C([H])([H])C([H])([H])C2([H])[H] [H]N1C(=O)[C@]2([H])N(C(=O)[C@@]([H])(N([H])C(=O)[C@]([H])(N([H])C(=O)[C@]1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])SC(=O)C([H])([H])[H])C([H])([H])C([H])([H])OC([H])([H])C([H])([H])SC(=O)C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C2([H])[H] [H]N1\C(=C(\[H])C([H])([H])[H])C(=O)N([H])[C@]([H])(C(=O)O[C@]2([H])\C([H])=C([H])\C([H])([H])C([H])([H])SSC([H])([H])[C@@]([H])(N([H])C(=O)[C@]([H])(N([H])C(=O)C2([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])C1=O)C([H])(C([H])([H])[H])C([H])([H])[H] [H]ON([H])C(=O)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N(C(=O)N([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H] [H]ON([H])C(=O)C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1C2=C([H])C([H])=C([H])C([H])=C2C2=C1C([H])([H])C([H])([H])N(C([H])([H])[H])C2([H])[H] ONC(=O)C1=CCCCC1 CC1=CC(=CC(C)=C1)C(=O)NOCCCCCC(=O)NO CC1=C(C)C=C(C=C1)C(=O)NOCCCCCC(=O)NO