[H]C1=C2N(C(=O)N(\C1=N\C1=C(C([H])=C(C([H])=C1C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])C1=C2C([H])=C(OC([H])([H])[H])C(OC([H])([H])[H])=C1[H]
[H]N1C(=O)C(C#N)=C([H])C(C2=C([H])C([H])=NC([H])=C2[H])=C1C([H])([H])[H]
[H]N(C1=NC([H])=NC2=C1C([H])=C([H])C(=C2[H])C1=NN([H])C(=O)C([H])([H])[C@@]1([H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1C(=NC2=C1C(=O)N(C1=N[C@]3([H])C([H])([H])C([H])([H])C([H])([H])[C@]3([H])N21)C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1C(=NC2=C1C(=O)N(C1=N[C@]3([H])C([H])([H])C([H])([H])C([H])([H])[C@]3([H])N21)C([H])([H])[H])C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N1C(=NC2=C1C(=O)N(C1=NC3(C([H])([H])N21)C([H])([H])C([H])([H])C([H])([H])C3([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1C(=NC2=C1C(=O)N(C1=NC3(C([H])([H])N21)C([H])([H])C([H])([H])C([H])([H])C3([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]OC1=C(O[H])C(=C([H])C([H])=C1[H])C([H])([H])N1C(=NC2=C1C(=O)N(C1=N[C@]3([H])C([H])([H])C([H])([H])C([H])([H])[C@]3([H])N21)C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N1C(=NC2=C1C(=O)N(C1=N[C@]3([H])C([H])([H])C([H])([H])C([H])([H])[C@]3([H])N21)C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N1C(=NC2=C1C(=O)N(C1=N[C@]3([H])C([H])([H])C([H])([H])C([H])([H])[C@]3([H])N21)C([H])([H])C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1C(=NC2=C1C(=O)N(C1=N[C@]3([H])C([H])([H])C([H])([H])C([H])([H])[C@]3([H])N21)C([H])([H])[H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N1C2=C(N=C1C([H])([H])C([H])([H])C([H])([H])[H])C(=O)N(C1=N[C@]3([H])C([H])([H])C([H])([H])C([H])([H])[C@]3([H])N21)C([H])([H])[H]
[H]N1N=C(C2=C1N1C(=N[C@]3([H])C([H])([H])C([H])([H])C([H])([H])[C@]13[H])N(C2=O)C([H])([H])[H])C([H])([H])[H]
[H]N1C(=NC2=C1C(=O)N(C1=N[C@]3([H])C([H])([H])C([H])([H])C([H])([H])[C@]3([H])N21)C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C1=NN(C2=C1C(=O)N(C1=N[C@]3([H])C([H])([H])C([H])([H])C([H])([H])[C@]3([H])N21)C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])C([H])=C(C([H])=N1)C([H])([H])N1C(=NC2=C1C(=O)N(C1=N[C@]3([H])C([H])([H])C([H])([H])C([H])([H])[C@]3([H])N21)C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N1C([H])=C([H])N=C1C([H])([H])C1=NC2=C(N1C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C(=O)N(C1=N[C@]3([H])C([H])([H])C([H])([H])C([H])([H])[C@]3([H])N21)C([H])([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1C(=NC2=C1C(=O)N(C1=N[C@]3([H])C([H])([H])C([H])([H])C([H])([H])[C@]3([H])N21)C([H])([H])[H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H]
[H]N1C(=NC2=C1C(=O)N(C1=N[C@]3([H])C([H])([H])C([H])([H])C([H])([H])[C@]3([H])N21)C([H])([H])[H])C([H])([H])C1([H])C([H])([H])C1([H])[H]
[H]N1C(=NC2=C1C(=O)N(C1=N[C@]3([H])C([H])([H])C([H])([H])C([H])([H])[C@]3([H])N21)C([H])([H])[H])C#CC1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N1C2=C(N=C1C([H])([H])N(C([H])([H])[H])C([H])([H])[H])C(=O)N(C1=N[C@]3([H])C([H])([H])C([H])([H])C([H])([H])[C@]3([H])N21)C([H])([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C1=NC2=C(N1C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C(=O)N(C1=NC3(C([H])([H])N21)C([H])([H])C([H])([H])C([H])([H])C3([H])[H])C([H])([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1C(=NC2=C1C(=O)N(C1=N[C@]3([H])C([H])([H])C([H])([H])C([H])([H])[C@]3([H])N21)C([H])([H])[H])C([H])([H])OC([H])([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1C(=NC2=C1C(=O)N(C1=N[C@]3([H])C([H])([H])C([H])([H])C([H])([H])[C@]3([H])N21)C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1C(=NC2=C1N1C(=NC3(C1([H])[H])C([H])([H])C([H])([H])C([H])([H])C3([H])[H])N(C2=O)C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1C(=NC2=C1C(=O)N(C1=N[C@]3([H])C([H])([H])C([H])([H])C([H])([H])[C@]3([H])N21)C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N1C(=NC2=C1C(=O)N(C1=N[C@]3([H])C([H])([H])C([H])([H])C([H])([H])[C@]3([H])N21)C([H])([H])[H])C(F)(F)F
[H]N1C2=C(N=C1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C(=O)N(C1=N[C@]3([H])C([H])([H])C([H])([H])C([H])([H])[C@]3([H])N21)C([H])([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1C(=NC2=C1C(=O)N(C1=N[C@]3([H])C([H])([H])C([H])([H])C([H])([H])[C@]3([H])N21)C([H])([H])[H])C([H])([H])C1([H])C([H])([H])C1([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C1=C2C(=NN1C([H])([H])[H])N1C(=N[C@@]([H])(C1([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])N(C2=O)C([H])([H])[H]
[H]N1C2=C(N=C1C([H])([H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C(=O)N(C1=N[C@]3([H])C([H])([H])C([H])([H])C([H])([H])[C@]3([H])N21)C([H])([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C1=NC2=C(N1C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C(=O)N(C1=NC3(C([H])([H])N21)C([H])([H])C([H])([H])C([H])([H])C3([H])[H])C([H])([H])[H]
[H]N1C(=NC2=C1C(=O)N(C1=N[C@]3([H])C([H])([H])C([H])([H])C([H])([H])[C@]3([H])N21)C([H])([H])[H])C([H])([H])[H]
[H]N1C(=NC2=C1C(=O)N(C1=N[C@]3([H])C([H])([H])C([H])([H])C([H])([H])[C@]3([H])N21)C([H])([H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1C(=NC2=C1C(=O)N(C1=N[C@]3([H])C([H])([H])C([H])([H])C([H])([H])[C@]3([H])N21)C([H])([H])[H])C(F)(F)F
[H]N1C(=NC2=C1C(=O)N(C1=N[C@]3([H])C([H])([H])C([H])([H])C([H])([H])[C@]3([H])N21)C([H])([H])[H])C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C1=NC2=C(N1C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C(=O)N(C1=N[C@]3([H])C([H])([H])C([H])([H])C([H])([H])[C@]3([H])N21)C([H])([H])[H]
[H]N1C([H])=C([H])N=C1C([H])([H])N1C(=NC2=C1C(=O)N(C1=N[C@]3([H])C([H])([H])C([H])([H])C([H])([H])[C@]3([H])N21)C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C1=C2C(=NN1C([H])([H])[H])N1C(=N[C@]3([H])C([H])([H])C([H])([H])C([H])([H])[C@]13[H])N(C2=O)C([H])([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1N=C(C2=C1N1C(=N[C@]3([H])C([H])([H])C([H])([H])C([H])([H])[C@]13[H])N(C2=O)C([H])([H])[H])C([H])([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C1=C2C(=NN1C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])N1C(=N[C@]3([H])C([H])([H])C([H])([H])C([H])([H])[C@]13[H])N(C2=O)C([H])([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C1=C2C(=NN1C([H])([H])[H])N1C(=NC(C([H])([H])[H])(C([H])([H])[H])C1([H])[H])N(C2=O)C([H])([H])[H]
[H]C1=NN(C2=C1C(=O)N(C1=N[C@]3([H])C([H])([H])C([H])([H])C([H])([H])[C@]3([H])N21)C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C1=NC2=C(N1C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C(=O)N(C1=N[C@]3([H])C([H])([H])C([H])([H])C([H])([H])[C@]3([H])N21)C([H])([H])[H]
[H]N1C(=NC2=C1C(=O)N(C1=NC3(C([H])([H])N21)C([H])([H])C([H])([H])C([H])([H])C3([H])[H])C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N1C2=C(N([H])[C@]1([H])C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C(=O)N(C1=NC3(C([H])([H])N21)C([H])([H])C([H])([H])C([H])([H])C3([H])[H])C([H])([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C1=C2C(=NN1C([H])([H])[H])N1C(=NC3(C1([H])[H])C([H])([H])C([H])([H])C([H])([H])C3([H])[H])N(C2=O)C([H])([H])[H]
[H]N1N=C(C2=C1N1C(=N[C@]3([H])C([H])([H])C([H])([H])C([H])([H])[C@]13[H])N(C2=O)C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N1C(=NC2=C1C(=O)N(C1=NC3(C([H])([H])N21)C([H])([H])C([H])([H])C([H])([H])C3([H])[H])C([H])([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C1=NC2=C(N1C([H])([H])[H])C(=O)N(C1=NC3(C([H])([H])N21)C([H])([H])C([H])([H])C([H])([H])C3([H])[H])C([H])([H])[H]
[H]N1N=NC2=C1C(=O)N([H])C(=N2)C1=C(OC([H])([H])C([H])([H])C([H])([H])[H])C([H])=C([H])C([H])=C1[H]
[H]OC(=O)C1([H])C([H])([H])C([H])([H])N(C2=NC3=C([H])C([H])=C(Cl)C([H])=C3C(=N2)N([H])C([H])([H])C2=C([H])C([H])=C3OC([H])([H])OC3=C2[H])C([H])([H])C1([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1C(=NC2=C1C(=O)N(C1=NC3(C([H])([H])N21)C([H])([H])C([H])([H])C([H])([H])C3([H])[H])C([H])([H])[H])C([H])([H])C1([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]C1=C([H])C([H])=C(C#CC2=NC3=C(N2C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C(=O)N(C2=N[C@]4([H])C([H])([H])C([H])([H])C([H])([H])[C@]4([H])N32)C([H])([H])[H])C([H])=C1[H]
[H]N1C2=C(N=C1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C(=O)N(C1=N[C@]3([H])C([H])([H])C([H])([H])C([H])([H])[C@]3([H])N21)C([H])([H])[H]
[H]N1C2=C(N=C1C([H])([H])C([H])([H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C(=O)N(C1=N[C@@]([H])(C([H])([H])N21)C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H]
[H]N1C2=C(N=C1C([H])([H])C([H])([H])[H])C(=O)N(C1=N[C@]3([H])C([H])([H])C([H])([H])C([H])([H])[C@]3([H])N21)C([H])([H])[H]
[H]N1C2=C(N=C1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C(=O)N(C1=N[C@@]([H])(C([H])([H])N21)C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H]
[H]N1C2=C(N=C1C([H])([H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])C(=O)N(C1=N[C@@]([H])(C([H])([H])N21)C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H]
[H]N1C2=C(N=C1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C(=O)N(C1=NC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])N21)C([H])([H])[H]
[H]N1C2=C(N=C1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C(=O)N(C1=NC3(C([H])([H])N21)C([H])([H])C([H])([H])C([H])([H])C3([H])[H])C([H])([H])[H]
[H]N1C2=C([H])C([H])=C([H])C([H])=C2C2=C1[C@]([H])(N1C(=O)N(C(=O)[C@@]1([H])C2([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C1=C([H])C([H])=NC([H])=C1[H]
[H]N1C2=C([H])C([H])=C([H])C([H])=C2C2=C1[C@]([H])(N1C(=O)C([H])([H])N(C(=O)[C@@]1([H])C2([H])[H])C([H])([H])C([H])([H])[H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]N1C2=C(C([H])=C([H])C([H])=C2[H])C2=C1[C@]([H])(N1C(=O)C([H])([H])N(C(=O)[C@]1([H])C2([H])[H])C([H])([H])[H])C1=C([H])C([H])=C2OC([H])([H])OC2=C1[H]
[H]N1C2=C([H])C([H])=C([H])C([H])=C2C2=C1[C@]([H])(N1C(=O)C([H])([H])N(C(=O)[C@@]1([H])C2([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]N1C2=C(C([H])=C([H])C([H])=C2[H])C2=C1[C@]([H])(N1C(=O)C([H])([H])N(C(=O)[C@@]1([H])C2([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C1=C([H])C2=C(OC([H])([H])O2)C([H])=C1[H]
[H]N1C2=C([H])C([H])=C([H])C([H])=C2C2=C1[C@]([H])(N1C(=O)N(C(=O)[C@]1([H])C2([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]N1C2=C(C([H])=C([H])C([H])=C2[H])C2=C1[C@]([H])(N1C(=O)C([H])([H])N([H])C(=O)[C@@]1([H])C2([H])[H])C1=C([H])C2=C(OC([H])([H])O2)C([H])=C1[H]
[H]N1C2=C([H])C([H])=C([H])C([H])=C2C2=C1[C@]([H])(N1C(=O)N(C([H])([H])[H])C([H])([H])[C@@]1([H])C2([H])[H])C1=C([H])C2=C(OC([H])([H])O2)C([H])=C1[H]
[H]N1C2=C(C([H])=C([H])C([H])=C2[H])C2=C1[C@]([H])(N1C(=O)C([H])([H])N(C(=O)[C@@]1([H])C2([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])C1=C([H])C2=C(OC([H])([H])O2)C([H])=C1[H]
[H]N1C2=C([H])C([H])=C([H])C([H])=C2C2=C1[C@@]([H])(N1C(=O)C([H])([H])N(C(=O)[C@@]1([H])C2([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N1C2=C([H])C([H])=C([H])C([H])=C2C2=C1[C@]([H])(N1C(=O)C([H])([H])N(C(=O)[C@@]1([H])C2([H])[H])C([H])([H])C1([H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])[H]
[H]N1C2=C([H])C([H])=C([H])C([H])=C2C2=C1[C@@]([H])(N1C(=O)N(C(=O)[C@@]1([H])C2([H])[H])C([H])([H])[H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]N1C2=C([H])C([H])=C([H])C([H])=C2C2=C1[C@@]([H])(N1C(=O)C([H])([H])N(C(=O)[C@@]1([H])C2([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C1=C([H])C([H])=C(C#N)C([H])=C1[H]
[H]N1C2=C([H])C([H])=C([H])C([H])=C2C2=C1[C@@]([H])(N1C(=O)C([H])([H])N(C(=O)[C@@]1([H])C2([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]N1C2=C([H])C([H])=C([H])C([H])=C2C2=C1[C@@]([H])(N1C(=O)N(C(=O)[C@@]1([H])C2([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]N1C2=C([H])C([H])=C([H])C([H])=C2C2=C1[C@]([H])(N1C(=O)C([H])([H])N(C(=O)[C@@]1([H])C2([H])[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C1=C([H])C2=C(OC([H])([H])O2)C([H])=C1[H]
[H]N1C2=C([H])C([H])=C([H])C([H])=C2C2=C1[C@@]([H])(N1C(=O)N(C(=O)[C@@]1([H])C2([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C2=C(OC([H])([H])O2)C([H])=C1[H]
[H]N1C(=O)C2=C(N=C1C1=C(OC([H])([H])C([H])([H])[H])C([H])=C([H])C(=C1[H])S(=O)(=O)N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H])C(=NN2C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]N1C2=C(C([H])=C([H])C([H])=C2[H])C2=C1[C@]([H])(N1C(=O)C([H])([H])N(C(=O)[C@@]1([H])C2([H])[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]N1C2=C([H])C([H])=C([H])C([H])=C2C2=C1[C@@]([H])(N1C([H])([H])N(C(=O)[C@@]1([H])C2([H])[H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]N1C2=C([H])C([H])=C([H])C([H])=C2C2=C1[C@]([H])(N1C(=O)C([H])([H])N(C3=C([H])C([H])=C([H])C([H])=C3[H])C(=O)[C@@]1([H])C2([H])[H])C1=C([H])C2=C(OC([H])([H])O2)C([H])=C1[H]
[H]N1C2=C([H])C([H])=C([H])C([H])=C2C2=C1[C@]([H])(N1C(=O)C([H])([H])N(C3=C([H])C([H])=C(C([H])=C3[H])[N+]([O-])=O)C(=O)[C@@]1([H])C2([H])[H])C1=C([H])C2=C(OC([H])([H])O2)C([H])=C1[H]
[H]N1C2=C([H])C([H])=C([H])C([H])=C2C2=C1[C@]([H])(N1C(=O)C([H])([H])N(C3=C([H])C(=C([H])C([H])=C3[H])C([H])([H])[H])C(=O)[C@@]1([H])C2([H])[H])C1=C([H])C2=C(OC([H])([H])O2)C([H])=C1[H]
[H]N1C2=C([H])C([H])=C([H])C([H])=C2C2=C1[C@]([H])(N1C(=O)C([H])([H])N(C3=C([H])C(Cl)=C([H])C([H])=C3[H])C(=O)[C@@]1([H])C2([H])[H])C1=C([H])C2=C(OC([H])([H])O2)C([H])=C1[H]
[H]N1C2=C([H])C([H])=C([H])C([H])=C2C2=C1[C@]([H])(N1C(=O)C([H])([H])N(C3=C([H])C([H])=C(C([H])=C3[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C(=O)[C@@]1([H])C2([H])[H])C1=C([H])C2=C(OC([H])([H])O2)C([H])=C1[H]
[H]N1C2=C([H])C([H])=C([H])C([H])=C2C2=C1[C@]([H])(N1C(=O)C([H])([H])N(C3=C([H])C([H])=C(OC([H])([H])[H])C([H])=C3[H])C(=O)[C@@]1([H])C2([H])[H])C1=C([H])C2=C(OC([H])([H])O2)C([H])=C1[H]
[H]N1C2=C([H])C([H])=C([H])C([H])=C2C2=C1[C@]([H])(N1C(=O)C([H])([H])N(C3=C([H])SC([H])=C3[H])C(=O)[C@@]1([H])C2([H])[H])C1=C([H])C2=C(OC([H])([H])O2)C([H])=C1[H]
[H]N1C2=C([H])C([H])=C([H])C([H])=C2C2=C1[C@]([H])(N1C(=O)C([H])([H])N(C3=C([H])N=C([H])C([H])=C3[H])C(=O)[C@@]1([H])C2([H])[H])C1=C([H])C2=C(OC([H])([H])O2)C([H])=C1[H]
[H]N1C2=C([H])C([H])=C([H])C([H])=C2C2=C1[C@]([H])(N1C(=O)C([H])([H])N(C3=C([H])N=C([H])N=C3[H])C(=O)[C@@]1([H])C2([H])[H])C1=C([H])C2=C(OC([H])([H])O2)C([H])=C1[H]
[H]N1C2=C([H])C([H])=C([H])C([H])=C2C2=C1[C@]([H])(N1C(=O)C([H])([H])N(C3=C([H])C([H])=C(Cl)C([H])=C3[H])C(=O)[C@@]1([H])C2([H])[H])C1=C([H])C2=C(OC([H])([H])O2)C([H])=C1[H]
[H]N1C2=C([H])C([H])=C([H])C([H])=C2C2=C1[C@]([H])(N1C(=O)C([H])([H])N(C3=C([H])C([H])=C([H])S3)C(=O)[C@@]1([H])C2([H])[H])C1=C([H])C2=C(OC([H])([H])O2)C([H])=C1[H]
[H]N1C2=C([H])C([H])=C([H])C([H])=C2C2=C1[C@]([H])(N1C(=O)C([H])([H])N(C3=C([H])C([H])=C(C([H])=C3[H])C(F)(F)F)C(=O)[C@@]1([H])C2([H])[H])C1=C([H])C2=C(OC([H])([H])O2)C([H])=C1[H]
[H]N(C(=O)C([H])([H])C([H])([H])[H])C1=C(OC([H])([H])[H])C(=C2N=C([H])N=C(N([H])C([H])([H])C3=C([H])C([H])=C(OC([H])([H])[H])C(Cl)=C3[H])C2=C1[H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]N(C(=O)C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C1=C(OC([H])([H])[H])C(=C2N=C([H])N=C(N([H])C([H])([H])C3=C([H])C([H])=C(OC([H])([H])[H])C(Cl)=C3[H])C2=C1[H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]N(C(=O)C(F)(F)F)C1=C(OC([H])([H])[H])C(=C2N=C([H])N=C(N([H])C([H])([H])C3=C([H])C([H])=C(OC([H])([H])[H])C(Cl)=C3[H])C2=C1[H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]N(C(=O)C(F)(F)F)C1=C(OC([H])([H])[H])C(=C2N=C([H])N=C(N([H])C([H])([H])C3=C([H])C([H])=C(OC([H])([H])[H])C(Cl)=C3[H])C2=C1[H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H]
[H]C([H])=C([H])C([H])([H])C1=C2N=C([H])N=C(N([H])C([H])([H])C3=C([H])C([H])=C(OC([H])([H])[H])C(Cl)=C3[H])C2=C([H])C(N([H])C(=O)C([H])([H])C([H])([H])[H])=C1OC([H])([H])[H]
[H]C([H])=C([H])C([H])([H])C1=C2N=C([H])N=C(N([H])C([H])([H])C3=C([H])C([H])=C(OC([H])([H])[H])C(Cl)=C3[H])C2=C([H])C(N([H])C(=O)C([H])([H])C([H])([H])C([H])([H])[H])=C1OC([H])([H])[H]
[H]OC([H])([H])C([H])([H])C1=C2N=C([H])N=C(N([H])C([H])([H])C3=C([H])C([H])=C(OC([H])([H])[H])C(Cl)=C3[H])C2=C([H])C(N([H])C(=O)C([H])([H])[H])=C1OC([H])([H])[H]
[H]OC([H])([H])C([H])([H])C1=C2N=C([H])N=C(N([H])C([H])([H])C3=C([H])C([H])=C(OC([H])([H])[H])C(Cl)=C3[H])C2=C([H])C(N([H])C(=O)C2=C([H])C([H])=C([H])C([H])=N2)=C1OC([H])([H])[H]
[H]OC([H])([H])C([H])([H])C1=C2N=C([H])N=C(N([H])C([H])([H])C3=C([H])C([H])=C(OC([H])([H])[H])C(Cl)=C3[H])C2=C([H])C(N([H])C(=O)C([H])(C([H])([H])[H])C([H])([H])[H])=C1OC([H])([H])[H]
[H]OC([H])([H])C([H])([H])C1=C2N=C([H])N=C(N([H])C([H])([H])C3=C([H])C([H])=C(OC([H])([H])[H])C(Cl)=C3[H])C2=C([H])C(N([H])C(=O)C([H])([H])C([H])([H])[H])=C1OC([H])([H])[H]
[H]N(C1=NC([H])=NC2=C([H])C(Cl)=C(C([H])=C12)[N+]([O-])=O)C([H])([H])C1=C([H])C([H])=C(OC([H])([H])[H])C(Cl)=C1[H]
[H]N([H])C([H])([H])C([H])([H])N([H])C1=C(C([H])=C2C(=NC([H])=NC2=C1[H])N([H])C([H])([H])C1=C([H])C([H])=C(OC([H])([H])[H])C(Cl)=C1[H])[N+]([O-])=O
[H]N(C1=NC([H])=NC2=C([H])C(N(C([H])([H])[H])C([H])([H])[H])=C(C([H])=C12)[N+]([O-])=O)C([H])([H])C1=C([H])C([H])=C(OC([H])([H])[H])C(Cl)=C1[H]
[H]N(C1=NC([H])=NC2=C([H])C(OC([H])([H])[H])=C(C([H])=C12)[N+]([O-])=O)C([H])([H])C1=C([H])C([H])=C(OC([H])([H])[H])C(Cl)=C1[H]
[H]OC1=C(C([H])=C2C(=NC([H])=NC2=C1C([H])([H])C([H])=C([H])[H])N([H])C([H])([H])C1=C([H])C([H])=C(OC([H])([H])[H])C(Cl)=C1[H])[N+]([O-])=O
[H]C([H])=C([H])C([H])([H])C1=C2N=C([H])N=C(N([H])C([H])([H])C3=C([H])C([H])=C(OC([H])([H])[H])C(Cl)=C3[H])C2=C([H])C(=C1OC([H])([H])[H])[N+]([O-])=O
[H]N([H])C1=C(OC([H])([H])[H])C(=C2N=C([H])N=C(N([H])C([H])([H])C3=C([H])C([H])=C(OC([H])([H])[H])C(Cl)=C3[H])C2=C1[H])C([H])([H])C([H])=C([H])[H]
[H]N(C(=O)C1([H])C([H])([H])C1([H])[H])C1=C(OC([H])([H])[H])C(=C2N=C([H])N=C(N([H])C([H])([H])C3=C([H])C([H])=C(OC([H])([H])[H])C(Cl)=C3[H])C2=C1[H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]N(C(=O)C(F)(F)F)C1=C(OC([H])([H])[H])C(=C2N=C([H])N=C(N([H])C([H])([H])C3=C([H])C([H])=C(OC([H])([H])[H])C(Cl)=C3[H])C2=C1[H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]N([H])C([H])([H])C(=O)N([H])C1=C(OC([H])([H])[H])C(=C2N=C([H])N=C(N([H])C([H])([H])C3=C([H])C([H])=C(OC([H])([H])[H])C(Cl)=C3[H])C2=C1[H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]N(C(=O)C([H])([H])[H])C1=C(OC([H])([H])[H])C(=C2N=C([H])N=C(N([H])C([H])([H])C3=C([H])C([H])=C(OC([H])([H])[H])C(Cl)=C3[H])C2=C1[H])C([H])([H])C([H])([H])C([H])([H])[H]
[H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])N1C(=NC2=C1C(=O)N(C1=NC3(C([H])([H])N21)C([H])([H])C([H])([H])C([H])([H])C3([H])[H])C([H])([H])[H])C1=C([H])C([H])=C(C([H])=C1[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
[H]OC([H])([H])C([H])([H])C1=C2N=C([H])N=C(N([H])C([H])([H])C3=C([H])C([H])=C(OC([H])([H])[H])C(Cl)=C3[H])C2=C([H])C(N([H])S(=O)(=O)C([H])([H])[H])=C1OC([H])([H])[H]
[H]OC([H])([H])C([H])([H])C1=C2N=C([H])N=C(N([H])C([H])([H])C3=C([H])C([H])=C(OC([H])([H])[H])C(Cl)=C3[H])C2=C([H])C(N([H])S(=O)(=O)N(C([H])([H])[H])C([H])([H])[H])=C1OC([H])([H])[H]
[H]OC([H])([H])C([H])([H])C1=C2N=C([H])N=C(N([H])C([H])([H])C3=C([H])C([H])=C(OC([H])([H])[H])C(Cl)=C3[H])C2=C([H])C(N([H])C(=O)OC([H])([H])[H])=C1OC([H])([H])[H]
[H]OC([H])([H])C([H])([H])C1=C2N=C([H])N=C(N([H])C([H])([H])C3=C([H])C([H])=C(OC([H])([H])[H])C(Cl)=C3[H])C2=C([H])C(N([H])C(=O)OC([H])([H])C([H])([H])[H])=C1OC([H])([H])[H]
[H]OC([H])([H])C([H])([H])C1=C2N=C([H])N=C(N([H])C([H])([H])C3=C([H])C([H])=C(OC([H])([H])[H])C(Cl)=C3[H])C2=C([H])C(N(C(=O)OC([H])([H])[H])C([H])([H])[H])=C1OC([H])([H])[H]
[H]OC([H])([H])C([H])([H])C1=C2N=C([H])N=C(N([H])C([H])([H])C3=C([H])C([H])=C(OC([H])([H])[H])C(Cl)=C3[H])C2=C([H])C(N(C(=O)C([H])([H])C([H])([H])[H])C([H])([H])[H])=C1OC([H])([H])[H]
[H]OC([H])([H])C([H])([H])C1=C2N=C([H])N=C(N([H])C([H])([H])C3=C([H])C([H])=C(OC([H])([H])[H])C(Cl)=C3[H])C2=C([H])C(N(C(=O)C([H])([H])C([H])([H])[H])C([H])([H])C([H])([H])[H])=C1OC([H])([H])[H]
[H]OC([H])([H])C([H])([H])C1=C2N=C([H])N=C(N([H])C([H])([H])C3=C([H])C([H])=C(OC([H])([H])[H])C(Cl)=C3[H])C2=C([H])C(N(C(=O)C([H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])[H])=C1OC([H])([H])[H]
[H]OC([H])([H])C([H])([H])C1=C2N=C([H])N=C(N([H])C([H])([H])C3=C([H])C([H])=C(OC([H])([H])[H])C(Cl)=C3[H])C2=C([H])C(N(C(=O)C2([H])C([H])([H])C2([H])[H])C([H])([H])[H])=C1OC([H])([H])[H]
[H]N1C2=C(C([H])=C([H])C([H])=C2[H])C2=C1[C@@]([H])(N1C(=O)N(C(=O)[C@@]1([H])C2([H])[H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]N1C2=C([H])C([H])=C([H])C([H])=C2C2=C1[C@]([H])(N1C(=O)N(C(=O)[C@@]1([H])C2([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C1=C([H])C([H])=C([H])C(Cl)=C1[H]
[H]N1C([H])=C2N=C3C([H])=C([H])C([H])=C([H])C3=C2C([H])=C1C(=O)OC([H])([H])C([H])([H])[H]
[H]N1C2=C(C([H])=C([H])C([H])=C2[H])C2=C1[C@@]([H])(N1C(=O)N(C(=O)[C@@]1([H])C2([H])[H])C1([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]N1C(=O)N2[C@@]([H])(C1=O)C([H])([H])C1=C(N([H])C3=C1C([H])=C([H])C([H])=C3[H])[C@]2([H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]N1C2=C([H])C([H])=C([H])C([H])=C2C2=C1[C@@]([H])(N1C(=O)N(C(=O)[C@@]1([H])C2([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C1=C(OC([H])([H])[H])C([H])=C([H])C([H])=C1[H]
[H]N1C2=C([H])C([H])=C([H])C([H])=C2C2=C1[C@@]([H])(N1C(=O)N(C(=O)[C@@]1([H])C2([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C1=C([H])C([H])=C(C#N)C([H])=C1[H]
[H]N1C2=C(C([H])=C([H])C([H])=C2[H])C2=C1[C@]([H])(N1C(=O)N(C(=O)[C@@]1([H])C2([H])[H])C([H])([H])C([H])([H])[H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]N1C2=C(C([H])=C([H])C([H])=C2[H])C2=C1[C@@]([H])(N1C(=O)N(C(=O)[C@@]1([H])C2([H])[H])C([H])([H])C1=C([H])N=C([H])C([H])=C1[H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]N1C2=C([H])C([H])=C([H])C([H])=C2C2=C1[C@]([H])(N1C(=O)N(C(=O)[C@@]1([H])C2([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C1=C([H])OC([H])=C1[H]
[H]N1C2=C([H])C([H])=C([H])C([H])=C2C2=C1[C@]([H])(N1C(=O)N(C(=O)[C@@]1([H])C2([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]N1C2=C(C([H])=C([H])C([H])=C2[H])C2=C1[C@@]([H])(N1C(=O)N(C(=O)[C@@]1([H])C2([H])[H])C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=N1)C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]C1=C([H])C([H])=C2C(=C1[H])N(C1=C2C([H])([H])[C@@]2([H])N(C(=O)N(C2=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])[C@@]1([H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])C([H])([H])[H]
[H]N1C2=C([H])C([H])=C([H])C([H])=C2C2=C1[C@]([H])(N1C(=O)N(C(=O)[C@@]1([H])C2([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C1=C([H])SC([H])=C1[H]
[H]N1C2=C(C([H])=C([H])C([H])=C2[H])C2=C1[C@@]([H])(N1C(=O)N(C(=O)[C@@]1([H])C2([H])[H])C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])[H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]N1C2=C([H])C([H])=C([H])C([H])=C2C2=C1[C@@]([H])(N1C(=O)N(C(=O)[C@@]1([H])C2([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C1=C([H])C([H])=C(Cl)C([H])=C1[H]
[H]N1C2=C([H])C([H])=C([H])C([H])=C2C2=C1[C@]([H])(N1C(=O)N(C(=O)[C@@]1([H])C2([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])C1=C([H])N=C([H])C([H])=C1[H]
[H]\C(=C(\[H])C1=C(OC([H])([H])[H])C([H])=C(OC([H])([H])[H])C(OC([H])([H])[H])=C1[H])C(=O)C1=C(OC([H])([H])[H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]\C(=C(\[H])C1=C(OC([H])([H])[H])C([H])=C([H])C(OC([H])([H])[H])=C1[H])C(=O)C1=C(OC([H])([H])[H])C([H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]\C(=C(\[H])C1=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C([H])=C1[H])C(=O)C1=C(OC([H])([H])[H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C([H])=C1OC([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H]
[H]\C(=C(\[H])C1=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C([H])=C1[H])C(=O)C1=C([H])C(OC([H])([H])[H])=C([H])C([H])=C1OC([H])([H])[H]
[H]\C(=C(\[H])C1=C([H])C(OC([H])([H])[H])=C([H])C([H])=C1[H])C(=O)C1=C2OC([H])([H])OC2=C(OC([H])([H])[H])C2=C1C([H])([H])C([H])([H])N(C([H])([H])[H])C2([H])[H]
[H]N1C2=C([H])C([H])=C([H])C([H])=C2C2=C1[C@]([H])(N1C(=O)C([H])([H])N(C(=O)[C@@]1([H])C2([H])[H])[C@@]1([H])C([H])([H])N(C([H])([H])C2=NC([H])=C([H])N2C([H])([H])[H])C([H])([H])C1([H])[H])C1=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]OC1=C(OC([H])([H])[H])C([H])=C([H])C(=C1[H])[C@@]1([H])N2C(=O)C([H])([H])N(C(=O)[C@@]2([H])C([H])([H])C2=C1N([H])C1=C([H])C([H])=C([H])C([H])=C21)[C@@]1([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]
[H]N1C2=C(C([H])=C([H])C([H])=C2[H])C2=C1[C@]([H])(N1C(=O)C([H])([H])N(C(=O)[C@@]1([H])C2([H])[H])[C@@]1([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H])C1=C([H])C(OC([H])([H])[H])=C(OC([H])([H])[H])C([H])=C1[H]
[H]N(C(=O)OC(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])[C@@]([H])(N2C(=O)[C@]3([H])N(C(=O)C2([H])[H])[C@@]([H])(C2=C(C4=C([H])C([H])=C([H])C([H])=C4N2[H])C3([H])[H])C2=C([H])C3=C(OC([H])([H])O3)C([H])=C2[H])C1([H])[H]
[H]N1C2=C([H])C([H])=C([H])C([H])=C2C2=C1[C@]([H])(N1C(=O)C([H])([H])N(C(=O)[C@@]1([H])C2([H])[H])[C@@]1([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H])C1=C([H])C2=NSN=C2C([H])=C1[H]
[H]N1C2=C([H])C([H])=C([H])C([H])=C2C2=C1[C@]([H])(N1C(=O)C([H])([H])N(C(=O)[C@@]1([H])C2([H])[H])[C@@]1([H])C([H])([H])N(C([H])([H])C(=O)N(C([H])([H])[H])C([H])([H])[H])C([H])([H])C1([H])[H])C1=C([H])C2=C(OC([H])([H])O2)C([H])=C1[H]
[H]N1C2=C([H])C([H])=C([H])C([H])=C2C2=C1[C@]([H])(N1C(=O)C([H])([H])N(C(=O)[C@@]1([H])C2([H])[H])[C@@]1([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C([H])C([H])=N2)C([H])([H])C1([H])[H])C1=C([H])C2=C(OC([H])([H])O2)C([H])=C1[H]
[H]N1C2=C([H])C([H])=C([H])C([H])=C2C2=C1[C@]([H])(N1C(=O)C([H])([H])N(C(=O)[C@@]1([H])C2([H])[H])[C@@]1([H])C([H])([H])N(C([H])([H])C2=NC([H])=C([H])N2C([H])([H])[H])C([H])([H])C1([H])[H])C1=C([H])C2=C(OC([H])([H])O2)C([H])=C1[H]
[H]OC1=C(OC([H])([H])[H])C([H])=C(C([H])=C1[H])[C@@]1([H])N2C(=O)C([H])([H])N(C(=O)[C@@]2([H])C([H])([H])C2=C1N([H])C1=C([H])C([H])=C([H])C([H])=C21)[C@@]1([H])C([H])([H])N(C([H])([H])C2=C([H])C([H])=C([H])C([H])=C2[H])C([H])([H])C1([H])[H]