Target name

O14939: Phospholipase D2


  Protein function

May have a role in signal-induced cytoskeletal regulation and/or endocytosis.

  Database links

Uniprot primary ID O14939
PDB ID
DrugBank ID DB00122
BioGrid ID 111354
GuidetoPHARMACOLOGY ID 1434
PharmGKB ID PA33397
KEGG ID hsa:5338
DIP ID DIP-38903N
STRING ID 9606.ENSP00000263088
IntAct ID O14939
DMDM
BRENDA 3.1.4.4 4.2.1.1
Reactome R-HSA-2029485 R-HSA-1483148 R-HSA-1483166
SignaLink O14939
BioCyc
Entrez Gene (Gene ID) 5338
BindingDB O14939

  Model Performance Metrics

Fingerprint type Sensitivity SEN_std Specificity SPE_std Accuracy ACC_std F1-score F1-score_std AUC AUC_std MCC MCC_std Download model
FP2 fingerprints 0.982 0.004 0.986 0.000 0.984 0.005 0.984 0.005 1.000 0.000 0.971 0.009 Download
Estate fingerprints 0.990 0.000 0.930 0.003 0.960 0.000 0.960 0.000 0.995 0.005 0.923 0.005 Download
MACCS fingerprints 0.987 0.005 0.985 0.003 0.986 0.005 0.986 0.005 1.000 0.000 0.975 0.007 Download
Daylight fingerprints 0.970 0.000 0.990 0.000 0.980 0.000 0.980 0.000 1.000 0.000 0.970 0.000 Download
ECFP2 fingerprints 1.000 0.000 1.000 0.000 1.000 0.000 1.000 0.000 1.000 0.000 1.000 0.000 Download
ECFP4 fingerprints 1.000 0.000 1.000 0.000 1.000 0.000 1.000 0.000 1.000 0.000 1.000 0.000 Download
ECFP6 fingerprints 1.000 0.000 1.000 0.000 1.000 0.000 1.000 0.000 1.000 0.000 1.000 0.000 Download

  Download datasets

Positive dataset Negative dataset


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School of Pharmaceutical Sciences, Central South University. All rights reserved.

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