Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1G gives rise to T-type calcium currents. T-type calcium channels belong to the
| Uniprot primary ID | O43497 |
| PDB ID | |
| DrugBank ID | DB00661 DB05246 DB00593 DB00568 DB04841 DB00909 DB00347 |
| BioGrid ID | 114427 |
| GuidetoPHARMACOLOGY ID | 535 |
| PharmGKB ID | PA381 |
| KEGG ID | hsa:8913 |
| DIP ID | |
| STRING ID | 9606.ENSP00000352011 |
| IntAct ID | O43497 |
| DMDM | |
| BRENDA | |
| Reactome | R-HSA-419037 |
| SignaLink | |
| BioCyc | |
| Entrez Gene (Gene ID) | 8913 |
| BindingDB | O43497 |
| Fingerprint type | Sensitivity | SEN_std | Specificity | SPE_std | Accuracy | ACC_std | F1-score | F1-score_std | AUC | AUC_std | MCC | MCC_std | Download model |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| FP2 fingerprints | 0.929 | 0.003 | 0.863 | 0.005 | 0.896 | 0.005 | 0.900 | 0.000 | 0.960 | 0.000 | 0.796 | 0.005 | Download |
| Estate fingerprints | 0.856 | 0.008 | 0.744 | 0.007 | 0.800 | 0.007 | 0.810 | 0.007 | 0.885 | 0.005 | 0.604 | 0.012 | Download |
| MACCS fingerprints | 0.881 | 0.003 | 0.755 | 0.003 | 0.818 | 0.004 | 0.828 | 0.004 | 0.911 | 0.003 | 0.641 | 0.007 | Download |
| Daylight fingerprints | 0.774 | 0.011 | 0.814 | 0.007 | 0.794 | 0.005 | 0.791 | 0.007 | 0.870 | 0.000 | 0.590 | 0.011 | Download |
| ECFP2 fingerprints | 0.988 | 0.004 | 0.900 | 0.000 | 0.944 | 0.005 | 0.946 | 0.005 | 0.990 | 0.000 | 0.891 | 0.003 | Download |
| ECFP4 fingerprints | 0.980 | 0.000 | 0.940 | 0.000 | 0.960 | 0.000 | 0.960 | 0.000 | 0.990 | 0.000 | 0.916 | 0.005 | Download |
| ECFP6 fingerprints | 0.969 | 0.003 | 0.969 | 0.003 | 0.969 | 0.003 | 0.969 | 0.003 | 0.990 | 0.000 | 0.940 | 0.007 | Download |
| Positive dataset | Negative dataset |
The recommended browsers: Safari, Firefox, Chrome, IE(Ver.>8).
E-mail: jiedong@csu.edu.cn
 |
 |
 |
 |
 |
 |