Target name

O60755: Galanin receptor type 3


  Protein function

Receptor for the hormone galanin. Receptor for the hormone spexin-1 (PubMed:24517231).

  Database links

Uniprot primary ID O60755
PDB ID
DrugBank ID
BioGrid ID 114058
GuidetoPHARMACOLOGY ID 245
PharmGKB ID PA28547
KEGG ID hsa:8484
DIP ID
STRING ID 9606.ENSP00000249041
IntAct ID
DMDM
BRENDA
Reactome R-HSA-418594 R-HSA-375276
SignaLink
BioCyc
Entrez Gene (Gene ID) 8484
BindingDB O60755

  Model Performance Metrics

Fingerprint type Sensitivity SEN_std Specificity SPE_std Accuracy ACC_std F1-score F1-score_std AUC AUC_std MCC MCC_std Download model
FP2 fingerprints 0.516 0.015 0.764 0.013 0.640 0.009 0.590 0.013 0.757 0.008 0.292 0.019 Download
Estate fingerprints 0.696 0.013 0.616 0.014 0.656 0.011 0.671 0.007 0.695 0.008 0.314 0.018 Download
MACCS fingerprints 0.687 0.016 0.661 0.020 0.674 0.014 0.678 0.015 0.735 0.011 0.347 0.027 Download
Daylight fingerprints 0.558 0.015 0.710 0.000 0.634 0.007 0.604 0.013 0.697 0.007 0.271 0.014 Download
ECFP2 fingerprints 0.685 0.012 0.727 0.015 0.706 0.007 0.698 0.009 0.783 0.007 0.414 0.018 Download
ECFP4 fingerprints 0.589 0.020 0.801 0.021 0.695 0.016 0.658 0.019 0.773 0.009 0.401 0.032 Download
ECFP6 fingerprints 0.489 0.019 0.837 0.012 0.663 0.012 0.592 0.015 0.762 0.010 0.349 0.022 Download

  Download datasets

Positive dataset Negative dataset


Copyright @ 2012-2014 Computational Biology & Drug Design Group,
School of Pharmaceutical Sciences, Central South University. All rights reserved.

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