Target name

O96020: G1/S-specific cyclin-E2


  Protein function

Essential for the control of the cell cycle at the late G1 and early S phase.

  Database links

Uniprot primary ID O96020
PDB ID
DrugBank ID
BioGrid ID 114582
GuidetoPHARMACOLOGY ID
PharmGKB ID PA26155
KEGG ID hsa:9134
DIP ID DIP-31733N
STRING ID 9606.ENSP00000309181
IntAct ID O96020
DMDM
BRENDA
Reactome R-HSA-2559586 R-HSA-69202 R-HSA-69200 R-HSA-69563 R-HSA-1538133 R-HSA-187577
SignaLink O96020
BioCyc
Entrez Gene (Gene ID) 9134
BindingDB O96020

  Model Performance Metrics

Fingerprint type Sensitivity SEN_std Specificity SPE_std Accuracy ACC_std F1-score F1-score_std AUC AUC_std MCC MCC_std Download model
FP2 fingerprints 0.911 0.010 0.943 0.003 0.927 0.005 0.925 0.007 0.970 0.000 0.853 0.011 Download
Estate fingerprints 0.857 0.012 0.831 0.006 0.844 0.005 0.846 0.005 0.928 0.004 0.689 0.009 Download
MACCS fingerprints 0.920 0.000 0.864 0.004 0.892 0.004 0.894 0.005 0.963 0.005 0.789 0.006 Download
Daylight fingerprints 0.710 0.000 0.990 0.000 0.850 0.000 0.820 0.000 0.960 0.000 0.720 0.000 Download
ECFP2 fingerprints 0.916 0.005 0.942 0.005 0.929 0.003 0.927 0.005 0.980 0.000 0.861 0.011 Download
ECFP4 fingerprints 0.947 0.005 0.991 0.000 0.969 0.003 0.969 0.003 0.990 0.000 0.937 0.005 Download
ECFP6 fingerprints 0.925 0.008 0.999 0.003 0.962 0.004 0.961 0.006 0.990 0.000 0.928 0.006 Download

  Download datasets

Positive dataset Negative dataset


Copyright @ 2012-2014 Computational Biology & Drug Design Group,
School of Pharmaceutical Sciences, Central South University. All rights reserved.

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