Target name

P00760: Cationic trypsin


  Protein function

extracellular space, serine-type endopeptidase activity, proteolysis

  Database links

Uniprot primary ID P00760
PDB ID 1GHZ 1C1O 1C1N 3UY9 3LJJ 1C1T 3LJO 1SBW 1C1Q 1C1P 1O35 1TIO 2FTL 1LQE 1O3A 4ABJ 1O3C 1O3B 1O3E 1O3D 1O3G 2BZA 1O3I 1O3H 1O3K 1O3J 1O3M 1O3L 1O3O 1O3N 1O31 1O30 1O33 1O32 2ZHD 1O34 1O37 1O36 1O39 1O38 1O3F 3NK8 2FI5 2FI4 2FI3 1O2V 3UNR 3UNS 3UNQ 1AZ8 1C1R
DrugBank ID
BioGrid ID
GuidetoPHARMACOLOGY ID
PharmGKB ID
KEGG ID bta:615026 bta:780933
DIP ID
STRING ID 9913.ENSBTAP00000033392
IntAct ID P00760
DMDM
BRENDA 3.4.21.4
Reactome
SignaLink
BioCyc
Entrez Gene (Gene ID) 780933;615026
BindingDB P00760

  Model Performance Metrics

Fingerprint type Sensitivity SEN_std Specificity SPE_std Accuracy ACC_std F1-score F1-score_std AUC AUC_std MCC MCC_std Download model
FP2 fingerprints 0.742 0.004 0.898 0.005 0.820 0.000 0.806 0.005 0.930 0.000 0.650 0.007 Download
Estate fingerprints 0.789 0.003 0.895 0.005 0.842 0.004 0.836 0.005 0.938 0.004 0.690 0.007 Download
MACCS fingerprints 0.839 0.003 0.875 0.007 0.857 0.005 0.852 0.004 0.930 0.000 0.712 0.004 Download
Daylight fingerprints 0.742 0.008 0.892 0.005 0.817 0.005 0.802 0.006 0.860 0.000 0.640 0.008 Download
ECFP2 fingerprints 0.937 0.005 0.941 0.000 0.939 0.003 0.939 0.003 0.970 0.000 0.877 0.005 Download
ECFP4 fingerprints 0.970 0.000 0.956 0.003 0.963 0.005 0.963 0.005 0.980 0.000 0.930 0.005 Download
ECFP6 fingerprints 0.951 0.003 0.971 0.000 0.961 0.003 0.961 0.003 0.980 0.000 0.926 0.005 Download

  Download datasets

Positive dataset Negative dataset


Copyright @ 2012-2014 Computational Biology & Drug Design Group,
School of Pharmaceutical Sciences, Central South University. All rights reserved.

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