Details-Calcnet-TargetNet

Target name

P02550: Tubulin alpha-1A chain

Protein function

Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain.

Database links

Uniprot primary ID	P02550
PDB ID	3J6H 2HXF 1TUB 3J7I 2HXH 3J6E 3J6G 3J6F 4ABO 1IA0 1FFX 2P4N 3J6P
DrugBank ID
BioGrid ID
GuidetoPHARMACOLOGY ID
PharmGKB ID
KEGG ID
DIP ID
STRING ID	9823.ENSSSCP00000000199
IntAct ID	P02550
DMDM
BRENDA
Reactome
SignaLink
BioCyc
Entrez Gene (Gene ID)
BindingDB	P02550

Model Performance Metrics

Fingerprint type	Sensitivity	SEN_std	Specificity	SPE_std	Accuracy	ACC_std	F1-score	F1-score_std	AUC	AUC_std	MCC	MCC_std	Download model
FP2 fingerprints	0.880	0.009	0.938	0.005	0.909	0.007	0.907	0.011	0.962	0.004	0.817	0.018	Download
Estate fingerprints	0.790	0.012	0.818	0.013	0.804	0.012	0.801	0.012	0.908	0.004	0.611	0.022	Download
MACCS fingerprints	0.881	0.012	0.869	0.007	0.875	0.007	0.878	0.010	0.946	0.005	0.753	0.018	Download
Daylight fingerprints	0.712	0.018	0.940	0.011	0.826	0.013	0.805	0.014	0.928	0.004	0.668	0.025	Download
ECFP2 fingerprints	0.937	0.007	0.851	0.014	0.894	0.008	0.898	0.006	0.962	0.004	0.790	0.016	Download
ECFP4 fingerprints	0.932	0.008	0.910	0.006	0.921	0.006	0.921	0.006	0.970	0.000	0.838	0.009	Download
ECFP6 fingerprints	0.938	0.006	0.952	0.005	0.945	0.007	0.945	0.007	0.974	0.005	0.884	0.010	Download

Download datasets

Positive dataset

Negative dataset