Target name

P02550: Tubulin alpha-1A chain


  Protein function

Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain.

  Database links

Uniprot primary ID P02550
PDB ID 3J6H 2HXF 1TUB 3J7I 2HXH 3J6E 3J6G 3J6F 4ABO 1IA0 1FFX 2P4N 3J6P
DrugBank ID
BioGrid ID
GuidetoPHARMACOLOGY ID
PharmGKB ID
KEGG ID
DIP ID
STRING ID 9823.ENSSSCP00000000199
IntAct ID P02550
DMDM
BRENDA
Reactome
SignaLink
BioCyc
Entrez Gene (Gene ID)
BindingDB P02550

  Model Performance Metrics

Fingerprint type Sensitivity SEN_std Specificity SPE_std Accuracy ACC_std F1-score F1-score_std AUC AUC_std MCC MCC_std Download model
FP2 fingerprints 0.880 0.009 0.938 0.005 0.909 0.007 0.907 0.011 0.962 0.004 0.817 0.018 Download
Estate fingerprints 0.790 0.012 0.818 0.013 0.804 0.012 0.801 0.012 0.908 0.004 0.611 0.022 Download
MACCS fingerprints 0.881 0.012 0.869 0.007 0.875 0.007 0.878 0.010 0.946 0.005 0.753 0.018 Download
Daylight fingerprints 0.712 0.018 0.940 0.011 0.826 0.013 0.805 0.014 0.928 0.004 0.668 0.025 Download
ECFP2 fingerprints 0.937 0.007 0.851 0.014 0.894 0.008 0.898 0.006 0.962 0.004 0.790 0.016 Download
ECFP4 fingerprints 0.932 0.008 0.910 0.006 0.921 0.006 0.921 0.006 0.970 0.000 0.838 0.009 Download
ECFP6 fingerprints 0.938 0.006 0.952 0.005 0.945 0.007 0.945 0.007 0.974 0.005 0.884 0.010 Download

  Download datasets

Positive dataset Negative dataset


Copyright @ 2012-2014 Computational Biology & Drug Design Group,
School of Pharmaceutical Sciences, Central South University. All rights reserved.

The recommended browsers: Safari, Firefox, Chrome, IE(Ver.>8).
 E-mail: biomed@csu.edu.cn