Details-Calcnet-TargetNet

Target name

P04058: Acetylcholinesterase

Protein function

Terminates signal transduction at the neuromuscular junction by rapid hydrolysis of the acetylcholine released into the synaptic cleft. May be involved in cell-cell interactions.

Database links

Uniprot primary ID	P04058
PDB ID	5BWB 5BWC 1GPK 1GPN 2VT7 1EEA 2V97 1ZGB 1ZGC 2CKM 2V98 2W6C 2XI4 2V96 1H23 1H22 1JGA 2J4F 2VJA 2C4H 3ZV7 4W63 2BAG 2WG0 1W4L 1JGB 1OCE 3I6Z 2C58 1VXO 1VOT 1GQR 1VXR 2VT6 2VJB 2VJC 3I6M 2C5F 2C5G 2VJD 2J3Q 1GQS 2W9I 4TVK 2J3D 1ODC 1EA5 2WG1 2WG2 1AMN 4ACE
DrugBank ID
BioGrid ID
GuidetoPHARMACOLOGY ID
PharmGKB ID
KEGG ID
DIP ID
STRING ID
IntAct ID
DMDM
BRENDA	3.1.1.7
Reactome
SignaLink
BioCyc	MetaCyc:MONOMER-16823
Entrez Gene (Gene ID)
BindingDB	P04058

Model Performance Metrics

Fingerprint type	Sensitivity	SEN_std	Specificity	SPE_std	Accuracy	ACC_std	F1-score	F1-score_std	AUC	AUC_std	MCC	MCC_std	Download model
FP2 fingerprints	0.773	0.007	0.883	0.010	0.828	0.004	0.815	0.007	0.900	0.000	0.656	0.008	Download
Estate fingerprints	0.630	0.009	0.804	0.005	0.717	0.007	0.690	0.007	0.815	0.005	0.440	0.014	Download
MACCS fingerprints	0.727	0.012	0.807	0.003	0.767	0.011	0.757	0.011	0.836	0.005	0.540	0.019	Download
Daylight fingerprints	0.781	0.037	0.895	0.017	0.838	0.023	0.827	0.028	0.905	0.012	0.679	0.043	Download
ECFP2 fingerprints	0.859	0.003	0.879	0.005	0.869	0.003	0.863	0.005	0.939	0.003	0.732	0.006	Download
ECFP4 fingerprints	0.872	0.009	0.932	0.007	0.902	0.004	0.899	0.003	0.959	0.003	0.804	0.007	Download
ECFP6 fingerprints	0.859	0.003	0.955	0.004	0.907	0.005	0.900	0.005	0.958	0.004	0.817	0.008	Download

Download datasets

Positive dataset

Negative dataset