Target name

P05186: Alkaline phosphatase, tissue-nonspecific isozyme


  Protein function

This isozyme may play a role in skeletal mineralization.

  Database links

Uniprot primary ID P05186
PDB ID
DrugBank ID DB01143 DB06716
BioGrid ID 106750
GuidetoPHARMACOLOGY ID
PharmGKB ID PA24729
KEGG ID hsa:249
DIP ID
STRING ID 9606.ENSP00000363965
IntAct ID P05186
DMDM 68067533
BRENDA 3.1.3.1
Reactome
SignaLink
BioCyc
Entrez Gene (Gene ID) 249
BindingDB P05186

  Model Performance Metrics

Fingerprint type Sensitivity SEN_std Specificity SPE_std Accuracy ACC_std F1-score F1-score_std AUC AUC_std MCC MCC_std Download model
FP2 fingerprints 0.755 0.005 0.879 0.004 0.817 0.005 0.806 0.005 0.883 0.005 0.639 0.007 Download
Estate fingerprints 0.770 0.011 0.764 0.009 0.767 0.007 0.767 0.007 0.828 0.004 0.539 0.016 Download
MACCS fingerprints 0.774 0.007 0.768 0.006 0.771 0.003 0.774 0.005 0.856 0.005 0.547 0.007 Download
Daylight fingerprints 0.707 0.007 0.787 0.005 0.747 0.007 0.737 0.007 0.770 0.000 0.496 0.007 Download
ECFP2 fingerprints 0.846 0.008 0.782 0.013 0.814 0.007 0.819 0.007 0.910 0.000 0.631 0.011 Download
ECFP4 fingerprints 0.831 0.007 0.867 0.011 0.849 0.003 0.847 0.005 0.930 0.000 0.699 0.009 Download
ECFP6 fingerprints 0.803 0.005 0.889 0.005 0.846 0.005 0.839 0.003 0.925 0.005 0.692 0.006 Download

  Download datasets

Positive dataset Negative dataset


Copyright @ 2012-2014 Computational Biology & Drug Design Group,
School of Pharmaceutical Sciences, Central South University. All rights reserved.

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