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Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.
| Uniprot primary ID | P06737 |
| PDB ID | 1FC0 1L7X 2QLL 2ZB2 1FA9 3CEM 3DDW 1XOI 3DD1 1L5Q 1L5R 1L5S 3CEH 3DDS 3CEJ 1EXV 2ATI 1EM6 |
| DrugBank ID | DB00131 |
| BioGrid ID | 111794 |
| GuidetoPHARMACOLOGY ID | |
| PharmGKB ID | PA34068 |
| KEGG ID | hsa:5836 |
| DIP ID | |
| STRING ID | 9606.ENSP00000216392 |
| IntAct ID | P06737 |
| DMDM | 6648082 |
| BRENDA | 2.4.1.1 |
| Reactome | R-HSA-70221 |
| SignaLink | |
| BioCyc | MetaCyc:HS02099-MONOMER |
| Entrez Gene (Gene ID) | 5836 |
| BindingDB | P06737 |
| Fingerprint type | Sensitivity | SEN_std | Specificity | SPE_std | Accuracy | ACC_std | F1-score | F1-score_std | AUC | AUC_std | MCC | MCC_std | Download model |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| FP2 fingerprints | 0.957 | 0.005 | 0.961 | 0.000 | 0.959 | 0.003 | 0.959 | 0.003 | 0.990 | 0.000 | 0.915 | 0.005 | Download |
| Estate fingerprints | 0.941 | 0.003 | 0.919 | 0.000 | 0.930 | 0.000 | 0.930 | 0.000 | 0.970 | 0.000 | 0.859 | 0.003 | Download |
| MACCS fingerprints | 0.937 | 0.005 | 0.905 | 0.004 | 0.921 | 0.003 | 0.921 | 0.003 | 0.971 | 0.003 | 0.840 | 0.005 | Download |
| Daylight fingerprints | 0.879 | 0.003 | 0.981 | 0.003 | 0.930 | 0.000 | 0.930 | 0.000 | 0.959 | 0.003 | 0.869 | 0.003 | Download |
| ECFP2 fingerprints | 0.979 | 0.003 | 0.963 | 0.000 | 0.971 | 0.003 | 0.971 | 0.003 | 1.000 | 0.000 | 0.947 | 0.005 | Download |
| ECFP4 fingerprints | 0.979 | 0.003 | 0.981 | 0.000 | 0.980 | 0.000 | 0.980 | 0.000 | 1.000 | 0.000 | 0.968 | 0.004 | Download |
| ECFP6 fingerprints | 0.979 | 0.003 | 1.000 | 0.000 | 0.990 | 0.000 | 0.990 | 0.000 | 1.000 | 0.000 | 0.978 | 0.004 | Download |
| Positive dataset | Negative dataset |
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E-mail: biomed@csu.edu.cn
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