Target name

P06737: Glycogen phosphorylase, liver form


  Protein function

Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.

  Database links

Uniprot primary ID P06737
PDB ID 1FC0 1L7X 2QLL 2ZB2 1FA9 3CEM 3DDW 1XOI 3DD1 1L5Q 1L5R 1L5S 3CEH 3DDS 3CEJ 1EXV 2ATI 1EM6
DrugBank ID DB00131
BioGrid ID 111794
GuidetoPHARMACOLOGY ID
PharmGKB ID PA34068
KEGG ID hsa:5836
DIP ID
STRING ID 9606.ENSP00000216392
IntAct ID P06737
DMDM 6648082
BRENDA 2.4.1.1
Reactome R-HSA-70221
SignaLink
BioCyc MetaCyc:HS02099-MONOMER
Entrez Gene (Gene ID) 5836
BindingDB P06737

  Model Performance Metrics

Fingerprint type Sensitivity SEN_std Specificity SPE_std Accuracy ACC_std F1-score F1-score_std AUC AUC_std MCC MCC_std Download model
FP2 fingerprints 0.957 0.005 0.961 0.000 0.959 0.003 0.959 0.003 0.990 0.000 0.915 0.005 Download
Estate fingerprints 0.941 0.003 0.919 0.000 0.930 0.000 0.930 0.000 0.970 0.000 0.859 0.003 Download
MACCS fingerprints 0.937 0.005 0.905 0.004 0.921 0.003 0.921 0.003 0.971 0.003 0.840 0.005 Download
Daylight fingerprints 0.879 0.003 0.981 0.003 0.930 0.000 0.930 0.000 0.959 0.003 0.869 0.003 Download
ECFP2 fingerprints 0.979 0.003 0.963 0.000 0.971 0.003 0.971 0.003 1.000 0.000 0.947 0.005 Download
ECFP4 fingerprints 0.979 0.003 0.981 0.000 0.980 0.000 0.980 0.000 1.000 0.000 0.968 0.004 Download
ECFP6 fingerprints 0.979 0.003 1.000 0.000 0.990 0.000 0.990 0.000 1.000 0.000 0.978 0.004 Download

  Download datasets

Positive dataset Negative dataset


Copyright @ 2012-2014 Computational Biology & Drug Design Group,
School of Pharmaceutical Sciences, Central South University. All rights reserved.

The recommended browsers: Safari, Firefox, Chrome, IE(Ver.>8).
 E-mail: biomed@csu.edu.cn