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E-mail: biomed@csu.edu.cn
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Acid protease active in intracellular protein breakdown. Involved in the pathogenesis of several diseases such as breast cancer and possibly Alzheimer disease.
| Uniprot primary ID | P07339 |
| PDB ID | 1LYA 1LYB 4OBZ 4OC6 4OD9 1LYW |
| DrugBank ID | DB00030 |
| BioGrid ID | 107889 |
| GuidetoPHARMACOLOGY ID | 2345 |
| PharmGKB ID | PA27029 |
| KEGG ID | hsa:1509 |
| DIP ID | DIP-43906N |
| STRING ID | 9606.ENSP00000236671 |
| IntAct ID | P07339 |
| DMDM | 115717 |
| BRENDA | 3.4.23.5 |
| Reactome | R-HSA-1442490 R-HSA-2022377 R-HSA-2132295 |
| SignaLink | |
| BioCyc | MetaCyc:HS04183-MONOMER |
| Entrez Gene (Gene ID) | 1509 |
| BindingDB | P07339 |
| Fingerprint type | Sensitivity | SEN_std | Specificity | SPE_std | Accuracy | ACC_std | F1-score | F1-score_std | AUC | AUC_std | MCC | MCC_std | Download model |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| FP2 fingerprints | 0.901 | 0.003 | 0.879 | 0.003 | 0.890 | 0.000 | 0.891 | 0.003 | 0.950 | 0.000 | 0.783 | 0.005 | Download |
| Estate fingerprints | 0.830 | 0.000 | 0.770 | 0.000 | 0.800 | 0.000 | 0.806 | 0.005 | 0.890 | 0.000 | 0.601 | 0.003 | Download |
| MACCS fingerprints | 0.800 | 0.000 | 0.842 | 0.004 | 0.821 | 0.003 | 0.820 | 0.000 | 0.910 | 0.000 | 0.650 | 0.000 | Download |
| Daylight fingerprints | 0.880 | 0.000 | 0.920 | 0.000 | 0.900 | 0.000 | 0.893 | 0.005 | 0.910 | 0.000 | 0.790 | 0.000 | Download |
| ECFP2 fingerprints | 0.920 | 0.000 | 0.940 | 0.000 | 0.930 | 0.000 | 0.930 | 0.000 | 0.980 | 0.000 | 0.862 | 0.004 | Download |
| ECFP4 fingerprints | 0.921 | 0.003 | 0.979 | 0.004 | 0.950 | 0.000 | 0.950 | 0.000 | 0.990 | 0.000 | 0.902 | 0.004 | Download |
| ECFP6 fingerprints | 0.897 | 0.005 | 0.985 | 0.000 | 0.941 | 0.003 | 0.940 | 0.000 | 0.990 | 0.000 | 0.889 | 0.003 | Download |
| Positive dataset | Negative dataset |
The recommended browsers: Safari, Firefox, Chrome, IE(Ver.>8).
E-mail: biomed@csu.edu.cn
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