Target name

P07478: Trypsin-2


  Protein function

In the ileum, may be involved in defensin processing, including DEFA5.

  Database links

Uniprot primary ID P07478
PDB ID
DrugBank ID
BioGrid ID 111627
GuidetoPHARMACOLOGY ID
PharmGKB ID PA33833
KEGG ID
DIP ID
STRING ID
IntAct ID
DMDM 136413
BRENDA
Reactome R-HSA-1592389 R-HSA-1462054 R-HSA-1442490
SignaLink
BioCyc
Entrez Gene (Gene ID) 5645
BindingDB P07478

  Model Performance Metrics

Fingerprint type Sensitivity SEN_std Specificity SPE_std Accuracy ACC_std F1-score F1-score_std AUC AUC_std MCC MCC_std Download model
FP2 fingerprints 0.778 0.008 0.928 0.003 0.853 0.005 0.841 0.006 0.950 0.000 0.713 0.008 Download
Estate fingerprints 0.939 0.003 0.921 0.004 0.930 0.000 0.931 0.003 0.950 0.000 0.863 0.007 Download
MACCS fingerprints 0.790 0.005 0.892 0.003 0.841 0.003 0.831 0.003 0.930 0.000 0.687 0.005 Download
Daylight fingerprints 0.738 0.004 0.832 0.005 0.785 0.005 0.775 0.005 0.842 0.004 0.572 0.006 Download
ECFP2 fingerprints 0.930 0.000 0.936 0.006 0.933 0.005 0.933 0.005 0.971 0.003 0.870 0.005 Download
ECFP4 fingerprints 0.968 0.006 0.948 0.000 0.958 0.004 0.958 0.004 0.992 0.004 0.913 0.008 Download
ECFP6 fingerprints 0.956 0.007 0.982 0.005 0.969 0.006 0.969 0.006 0.997 0.005 0.938 0.009 Download

  Download datasets

Positive dataset Negative dataset


Copyright @ 2012-2014 Computational Biology & Drug Design Group,
School of Pharmaceutical Sciences, Central South University. All rights reserved.

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