Target name

P08842: Steryl-sulfatase


  Protein function

Conversion of sulfated steroid precursors to estrogens during pregnancy.

  Database links

Uniprot primary ID P08842
PDB ID 1P49
DrugBank ID DB06713
BioGrid ID 106905
GuidetoPHARMACOLOGY ID
PharmGKB ID PA36225
KEGG ID hsa:412
DIP ID
STRING ID 9606.ENSP00000217961
IntAct ID P08842
DMDM 135006
BRENDA 3.1.6.2
Reactome R-HSA-1660662 R-HSA-1663150
SignaLink
BioCyc
Entrez Gene (Gene ID) 412
BindingDB P08842

  Model Performance Metrics

Fingerprint type Sensitivity SEN_std Specificity SPE_std Accuracy ACC_std F1-score F1-score_std AUC AUC_std MCC MCC_std Download model
FP2 fingerprints 0.946 0.008 0.946 0.004 0.946 0.005 0.946 0.005 0.988 0.004 0.890 0.007 Download
Estate fingerprints 0.946 0.005 0.850 0.008 0.898 0.004 0.901 0.003 0.957 0.005 0.794 0.010 Download
MACCS fingerprints 0.957 0.005 0.907 0.003 0.932 0.004 0.932 0.004 0.970 0.000 0.868 0.006 Download
Daylight fingerprints 0.835 0.008 0.903 0.009 0.869 0.006 0.863 0.007 0.922 0.004 0.737 0.009 Download
ECFP2 fingerprints 0.987 0.005 0.961 0.003 0.974 0.005 0.974 0.005 1.000 0.000 0.948 0.004 Download
ECFP4 fingerprints 0.996 0.005 0.984 0.003 0.990 0.000 0.990 0.000 1.000 0.000 0.986 0.005 Download
ECFP6 fingerprints 0.980 0.007 0.998 0.005 0.989 0.003 0.989 0.003 1.000 0.000 0.977 0.008 Download

  Download datasets

Positive dataset Negative dataset


Copyright @ 2012-2014 Computational Biology & Drug Design Group,
School of Pharmaceutical Sciences, Central South University. All rights reserved.

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