Degrades casein, gelatins of types I, III, IV, and V, and fibronectin. Activates procollagenase.
Uniprot primary ID | P09237 |
PDB ID | 1MMP 2DDY 1MMQ 2Y6D 1MMR 2Y6C |
DrugBank ID | DB00786 |
BioGrid ID | 110459 |
GuidetoPHARMACOLOGY ID | 1631 |
PharmGKB ID | PA30887 |
KEGG ID | hsa:4316 |
DIP ID | |
STRING ID | 9606.ENSP00000260227 |
IntAct ID | P09237 |
DMDM | 116861 |
BRENDA | 3.4.24.23 |
Reactome | R-HSA-1592389 R-HSA-2022090 R-HSA-1474228 R-HSA-1442490 |
SignaLink | |
BioCyc | |
Entrez Gene (Gene ID) | 4316 |
BindingDB | P09237 |
Fingerprint type | Sensitivity | SEN_std | Specificity | SPE_std | Accuracy | ACC_std | F1-score | F1-score_std | AUC | AUC_std | MCC | MCC_std | Download model |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
FP2 fingerprints | 0.793 | 0.007 | 0.917 | 0.004 | 0.855 | 0.005 | 0.845 | 0.005 | 0.950 | 0.000 | 0.715 | 0.005 | Download |
Estate fingerprints | 0.888 | 0.004 | 0.832 | 0.005 | 0.860 | 0.000 | 0.863 | 0.005 | 0.944 | 0.005 | 0.718 | 0.004 | Download |
MACCS fingerprints | 0.870 | 0.000 | 0.872 | 0.003 | 0.871 | 0.003 | 0.870 | 0.000 | 0.950 | 0.000 | 0.746 | 0.005 | Download |
Daylight fingerprints | 0.709 | 0.007 | 0.959 | 0.000 | 0.834 | 0.005 | 0.809 | 0.006 | 0.960 | 0.000 | 0.688 | 0.006 | Download |
ECFP2 fingerprints | 0.973 | 0.005 | 0.949 | 0.000 | 0.961 | 0.003 | 0.961 | 0.003 | 0.990 | 0.000 | 0.926 | 0.005 | Download |
ECFP4 fingerprints | 0.971 | 0.003 | 0.969 | 0.000 | 0.970 | 0.000 | 0.970 | 0.000 | 0.990 | 0.000 | 0.946 | 0.005 | Download |
ECFP6 fingerprints | 0.968 | 0.004 | 0.974 | 0.000 | 0.971 | 0.003 | 0.971 | 0.003 | 0.990 | 0.000 | 0.946 | 0.005 | Download |
Positive dataset | Negative dataset |
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E-mail: biomed@csu.edu.cn