Catalyzes the first step in leukotriene biosynthesis, and thereby plays a role in inflammatory processes.
Uniprot primary ID | P12527 |
PDB ID | |
DrugBank ID | |
BioGrid ID | |
GuidetoPHARMACOLOGY ID | |
PharmGKB ID | |
KEGG ID | rno:25290 |
DIP ID | DIP-48659N |
STRING ID | 10116.ENSRNOP00000017633 |
IntAct ID | |
DMDM | |
BRENDA | 1.13.11.34 |
Reactome | |
SignaLink | |
BioCyc | |
Entrez Gene (Gene ID) | 25290 |
BindingDB | P12527 |
Fingerprint type | Sensitivity | SEN_std | Specificity | SPE_std | Accuracy | ACC_std | F1-score | F1-score_std | AUC | AUC_std | MCC | MCC_std | Download model |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
FP2 fingerprints | 0.854 | 0.005 | 0.844 | 0.004 | 0.849 | 0.003 | 0.849 | 0.003 | 0.929 | 0.003 | 0.700 | 0.007 | Download |
Estate fingerprints | 0.794 | 0.005 | 0.788 | 0.003 | 0.791 | 0.003 | 0.792 | 0.004 | 0.860 | 0.000 | 0.586 | 0.005 | Download |
MACCS fingerprints | 0.797 | 0.005 | 0.843 | 0.003 | 0.820 | 0.000 | 0.810 | 0.000 | 0.900 | 0.000 | 0.636 | 0.005 | Download |
Daylight fingerprints | 0.670 | 0.000 | 0.810 | 0.000 | 0.740 | 0.000 | 0.720 | 0.000 | 0.770 | 0.000 | 0.488 | 0.004 | Download |
ECFP2 fingerprints | 0.940 | 0.000 | 0.900 | 0.005 | 0.920 | 0.000 | 0.920 | 0.000 | 0.973 | 0.005 | 0.839 | 0.003 | Download |
ECFP4 fingerprints | 0.943 | 0.005 | 0.937 | 0.005 | 0.940 | 0.000 | 0.940 | 0.000 | 0.980 | 0.000 | 0.881 | 0.003 | Download |
ECFP6 fingerprints | 0.933 | 0.005 | 0.929 | 0.000 | 0.931 | 0.003 | 0.931 | 0.003 | 0.980 | 0.000 | 0.866 | 0.005 | Download |
Positive dataset | Negative dataset |
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E-mail: biomed@csu.edu.cn