Cell-surface glycoprotein having a role in immunoadhesion. Mediates in the adhesion of blood neutrophils in cytokine-activated endothelium through interaction with PSGL1/SELPLG. May have a role in capillary morphogenesis.
Uniprot primary ID | P16581 |
PDB ID | 1KJA 1ESL 1G1T 4C16 4CSY |
DrugBank ID | DB01136 |
BioGrid ID | 112301 |
GuidetoPHARMACOLOGY ID | |
PharmGKB ID | PA35640 |
KEGG ID | hsa:6401 |
DIP ID | DIP-58639N |
STRING ID | 9606.ENSP00000331736 |
IntAct ID | P16581 |
DMDM | 126180 |
BRENDA | |
Reactome | R-HSA-202733 |
SignaLink | |
BioCyc | |
Entrez Gene (Gene ID) | 6401 |
BindingDB | P16581 |
Fingerprint type | Sensitivity | SEN_std | Specificity | SPE_std | Accuracy | ACC_std | F1-score | F1-score_std | AUC | AUC_std | MCC | MCC_std | Download model |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
FP2 fingerprints | 0.889 | 0.003 | 1.000 | 0.000 | 0.949 | 0.003 | 0.940 | 0.000 | 0.989 | 0.003 | 0.899 | 0.003 | Download |
Estate fingerprints | 0.910 | 0.000 | 0.950 | 0.004 | 0.930 | 0.000 | 0.930 | 0.000 | 0.970 | 0.000 | 0.862 | 0.004 | Download |
MACCS fingerprints | 0.886 | 0.010 | 0.934 | 0.009 | 0.910 | 0.000 | 0.909 | 0.003 | 0.980 | 0.000 | 0.825 | 0.005 | Download |
Daylight fingerprints | 0.868 | 0.004 | 0.992 | 0.000 | 0.930 | 0.000 | 0.928 | 0.004 | 0.978 | 0.004 | 0.878 | 0.004 | Download |
ECFP2 fingerprints | 0.910 | 0.007 | 0.990 | 0.003 | 0.950 | 0.000 | 0.947 | 0.005 | 0.990 | 0.000 | 0.899 | 0.007 | Download |
ECFP4 fingerprints | 0.900 | 0.009 | 1.000 | 0.003 | 0.952 | 0.006 | 0.947 | 0.005 | 0.990 | 0.000 | 0.904 | 0.008 | Download |
ECFP6 fingerprints | 0.880 | 0.000 | 1.000 | 0.000 | 0.940 | 0.000 | 0.934 | 0.005 | 0.992 | 0.004 | 0.884 | 0.005 | Download |
Positive dataset | Negative dataset |
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E-mail: biomed@csu.edu.cn