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E-mail: biomed@csu.edu.cn
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Integrin alpha-V/beta-5 (ITGAV:ITGB5) is a receptor for fibronectin. It recognizes the sequence R-G-D in its ligand.
| Uniprot primary ID | P18084 |
| PDB ID | |
| DrugBank ID | |
| BioGrid ID | 109899 |
| GuidetoPHARMACOLOGY ID | |
| PharmGKB ID | PA29959 |
| KEGG ID | hsa:3693 |
| DIP ID | |
| STRING ID | 9606.ENSP00000296181 |
| IntAct ID | P18084 |
| DMDM | 124970 |
| BRENDA | |
| Reactome | R-HSA-216083 R-HSA-2129379 R-HSA-1236973 R-HSA-3000178 R-HSA-3000170 R-HSA-445355 |
| SignaLink | P18084 |
| BioCyc | |
| Entrez Gene (Gene ID) | 3693 |
| BindingDB | P18084 |
| Fingerprint type | Sensitivity | SEN_std | Specificity | SPE_std | Accuracy | ACC_std | F1-score | F1-score_std | AUC | AUC_std | MCC | MCC_std | Download model |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| FP2 fingerprints | 0.907 | 0.008 | 0.947 | 0.005 | 0.927 | 0.007 | 0.923 | 0.005 | 0.980 | 0.000 | 0.853 | 0.008 | Download |
| Estate fingerprints | 0.962 | 0.004 | 0.846 | 0.007 | 0.904 | 0.005 | 0.909 | 0.006 | 0.969 | 0.003 | 0.813 | 0.009 | Download |
| MACCS fingerprints | 0.957 | 0.009 | 0.907 | 0.005 | 0.932 | 0.004 | 0.936 | 0.005 | 0.971 | 0.003 | 0.865 | 0.012 | Download |
| Daylight fingerprints | 0.824 | 0.008 | 0.924 | 0.000 | 0.874 | 0.005 | 0.868 | 0.004 | 0.905 | 0.005 | 0.752 | 0.008 | Download |
| ECFP2 fingerprints | 0.971 | 0.006 | 0.965 | 0.006 | 0.968 | 0.004 | 0.968 | 0.004 | 0.990 | 0.000 | 0.933 | 0.007 | Download |
| ECFP4 fingerprints | 0.977 | 0.009 | 0.987 | 0.000 | 0.982 | 0.004 | 0.982 | 0.004 | 0.998 | 0.004 | 0.968 | 0.008 | Download |
| ECFP6 fingerprints | 0.937 | 0.007 | 0.995 | 0.000 | 0.966 | 0.005 | 0.966 | 0.005 | 0.999 | 0.003 | 0.935 | 0.007 | Download |
| Positive dataset | Negative dataset |
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E-mail: biomed@csu.edu.cn
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