Dopamine receptor whose activity is mediated by G proteins which inhibit adenylyl cyclase. Promotes cell proliferation (By similarity).
| Uniprot primary ID | P19020 |
| PDB ID | |
| DrugBank ID | |
| BioGrid ID | |
| GuidetoPHARMACOLOGY ID | 216 |
| PharmGKB ID | |
| KEGG ID | rno:29238 |
| DIP ID | |
| STRING ID | 10116.ENSRNOP00000031550 |
| IntAct ID | |
| DMDM | |
| BRENDA | |
| Reactome | R-RNO-418594 R-RNO-390651 |
| SignaLink | |
| BioCyc | |
| Entrez Gene (Gene ID) | 29238 |
| BindingDB | P19020 |
| Fingerprint type | Sensitivity | SEN_std | Specificity | SPE_std | Accuracy | ACC_std | F1-score | F1-score_std | AUC | AUC_std | MCC | MCC_std | Download model |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| FP2 fingerprints | 0.923 | 0.005 | 0.849 | 0.000 | 0.886 | 0.005 | 0.891 | 0.003 | 0.960 | 0.000 | 0.774 | 0.005 | Download |
| Estate fingerprints | 0.859 | 0.003 | 0.731 | 0.004 | 0.795 | 0.005 | 0.808 | 0.004 | 0.871 | 0.003 | 0.593 | 0.007 | Download |
| MACCS fingerprints | 0.948 | 0.004 | 0.812 | 0.005 | 0.880 | 0.000 | 0.889 | 0.003 | 0.950 | 0.000 | 0.771 | 0.006 | Download |
| Daylight fingerprints | 0.860 | 0.000 | 0.800 | 0.000 | 0.830 | 0.000 | 0.831 | 0.003 | 0.867 | 0.005 | 0.660 | 0.000 | Download |
| ECFP2 fingerprints | 0.964 | 0.005 | 0.916 | 0.000 | 0.940 | 0.000 | 0.940 | 0.000 | 0.990 | 0.000 | 0.877 | 0.005 | Download |
| ECFP4 fingerprints | 0.950 | 0.000 | 0.950 | 0.003 | 0.950 | 0.000 | 0.950 | 0.000 | 0.990 | 0.000 | 0.904 | 0.005 | Download |
| ECFP6 fingerprints | 0.908 | 0.006 | 0.974 | 0.004 | 0.941 | 0.003 | 0.941 | 0.003 | 0.990 | 0.000 | 0.887 | 0.007 | Download |
| Positive dataset | Negative dataset |
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E-mail: jiedong@csu.edu.cn
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