Target name

P19020: D(3) dopamine receptor


  Protein function

Dopamine receptor whose activity is mediated by G proteins which inhibit adenylyl cyclase. Promotes cell proliferation (By similarity).

  Database links

Uniprot primary ID P19020
PDB ID
DrugBank ID
BioGrid ID
GuidetoPHARMACOLOGY ID 216
PharmGKB ID
KEGG ID rno:29238
DIP ID
STRING ID 10116.ENSRNOP00000031550
IntAct ID
DMDM
BRENDA
Reactome R-RNO-418594 R-RNO-390651
SignaLink
BioCyc
Entrez Gene (Gene ID) 29238
BindingDB P19020

  Model Performance Metrics

Fingerprint type Sensitivity SEN_std Specificity SPE_std Accuracy ACC_std F1-score F1-score_std AUC AUC_std MCC MCC_std Download model
FP2 fingerprints 0.923 0.005 0.849 0.000 0.886 0.005 0.891 0.003 0.960 0.000 0.774 0.005 Download
Estate fingerprints 0.859 0.003 0.731 0.004 0.795 0.005 0.808 0.004 0.871 0.003 0.593 0.007 Download
MACCS fingerprints 0.948 0.004 0.812 0.005 0.880 0.000 0.889 0.003 0.950 0.000 0.771 0.006 Download
Daylight fingerprints 0.860 0.000 0.800 0.000 0.830 0.000 0.831 0.003 0.867 0.005 0.660 0.000 Download
ECFP2 fingerprints 0.964 0.005 0.916 0.000 0.940 0.000 0.940 0.000 0.990 0.000 0.877 0.005 Download
ECFP4 fingerprints 0.950 0.000 0.950 0.003 0.950 0.000 0.950 0.000 0.990 0.000 0.904 0.005 Download
ECFP6 fingerprints 0.908 0.006 0.974 0.004 0.941 0.003 0.941 0.003 0.990 0.000 0.887 0.007 Download

  Download datasets

Positive dataset Negative dataset


Copyright @ 2012-2014 Computational Biology & Drug Design Group,
School of Pharmaceutical Sciences, Central South University. All rights reserved.

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 E-mail: biomed@csu.edu.cn