Target name

P19156: Potassium-transporting ATPase alpha chain 1


  Protein function

Catalyzes the hydrolysis of ATP coupled with the exchange of H(+) and K(+) ions across the plasma membrane. Responsible for acid production in the stomach.

  Database links

Uniprot primary ID P19156
PDB ID 3IXZ 1IWF 1IWC 2YN9 2XZB 4UX1 4UX2
DrugBank ID
BioGrid ID
GuidetoPHARMACOLOGY ID
PharmGKB ID
KEGG ID ssc:397552
DIP ID
STRING ID 9823.ENSSSCP00000003126
IntAct ID P19156
DMDM
BRENDA 3.6.3.10
Reactome
SignaLink
BioCyc
Entrez Gene (Gene ID) 397552
BindingDB P19156

  Model Performance Metrics

Fingerprint type Sensitivity SEN_std Specificity SPE_std Accuracy ACC_std F1-score F1-score_std AUC AUC_std MCC MCC_std Download model
FP2 fingerprints 0.920 0.000 1.000 0.000 0.960 0.000 0.956 0.005 0.990 0.000 0.916 0.005 Download
Estate fingerprints 0.963 0.005 0.889 0.003 0.926 0.005 0.928 0.004 0.980 0.000 0.856 0.005 Download
MACCS fingerprints 0.918 0.004 0.958 0.003 0.938 0.004 0.938 0.004 0.990 0.000 0.878 0.006 Download
Daylight fingerprints 0.854 0.005 0.994 0.000 0.924 0.005 0.920 0.000 0.970 0.000 0.860 0.000 Download
ECFP2 fingerprints 0.979 0.003 0.999 0.000 0.989 0.003 0.989 0.003 1.000 0.000 0.970 0.000 Download
ECFP4 fingerprints 0.969 0.003 1.000 0.000 0.985 0.005 0.985 0.005 1.000 0.000 0.972 0.006 Download
ECFP6 fingerprints 0.930 0.000 1.000 0.000 0.967 0.005 0.967 0.005 1.000 0.000 0.930 0.000 Download

  Download datasets

Positive dataset Negative dataset


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 E-mail: biomed@csu.edu.cn