Catalyzes the hydrolysis of ATP coupled with the exchange of H(+) and K(+) ions across the plasma membrane. Responsible for acid production in the stomach.
| Uniprot primary ID | P19156 |
| PDB ID | 3IXZ 1IWF 1IWC 2YN9 2XZB 4UX1 4UX2 |
| DrugBank ID | |
| BioGrid ID | |
| GuidetoPHARMACOLOGY ID | |
| PharmGKB ID | |
| KEGG ID | ssc:397552 |
| DIP ID | |
| STRING ID | 9823.ENSSSCP00000003126 |
| IntAct ID | P19156 |
| DMDM | |
| BRENDA | 3.6.3.10 |
| Reactome | |
| SignaLink | |
| BioCyc | |
| Entrez Gene (Gene ID) | 397552 |
| BindingDB | P19156 |
| Fingerprint type | Sensitivity | SEN_std | Specificity | SPE_std | Accuracy | ACC_std | F1-score | F1-score_std | AUC | AUC_std | MCC | MCC_std | Download model |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| FP2 fingerprints | 0.920 | 0.000 | 1.000 | 0.000 | 0.960 | 0.000 | 0.956 | 0.005 | 0.990 | 0.000 | 0.916 | 0.005 | Download |
| Estate fingerprints | 0.963 | 0.005 | 0.889 | 0.003 | 0.926 | 0.005 | 0.928 | 0.004 | 0.980 | 0.000 | 0.856 | 0.005 | Download |
| MACCS fingerprints | 0.918 | 0.004 | 0.958 | 0.003 | 0.938 | 0.004 | 0.938 | 0.004 | 0.990 | 0.000 | 0.878 | 0.006 | Download |
| Daylight fingerprints | 0.854 | 0.005 | 0.994 | 0.000 | 0.924 | 0.005 | 0.920 | 0.000 | 0.970 | 0.000 | 0.860 | 0.000 | Download |
| ECFP2 fingerprints | 0.979 | 0.003 | 0.999 | 0.000 | 0.989 | 0.003 | 0.989 | 0.003 | 1.000 | 0.000 | 0.970 | 0.000 | Download |
| ECFP4 fingerprints | 0.969 | 0.003 | 1.000 | 0.000 | 0.985 | 0.005 | 0.985 | 0.005 | 1.000 | 0.000 | 0.972 | 0.006 | Download |
| ECFP6 fingerprints | 0.930 | 0.000 | 1.000 | 0.000 | 0.967 | 0.005 | 0.967 | 0.005 | 1.000 | 0.000 | 0.930 | 0.000 | Download |
| Positive dataset | Negative dataset |
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E-mail: jiedong@csu.edu.cn
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