Catalyzes the oxidative deamination of biogenic and xenobiotic amines and has important functions in the metabolism of neuroactive and vasoactive amines in the central nervous system and peripheral tissues. MAOB preferentially degrades benzylamine and phenylethylamine.
Uniprot primary ID | P19643 |
PDB ID | |
DrugBank ID | |
BioGrid ID | |
GuidetoPHARMACOLOGY ID | 2490 |
PharmGKB ID | |
KEGG ID | rno:25750 |
DIP ID | |
STRING ID | 10116.ENSRNOP00000043466 |
IntAct ID | |
DMDM | |
BRENDA | 1.4.3.4 |
Reactome | R-RNO-141333 |
SignaLink | |
BioCyc | |
Entrez Gene (Gene ID) | 25750 |
BindingDB | P19643 |
Fingerprint type | Sensitivity | SEN_std | Specificity | SPE_std | Accuracy | ACC_std | F1-score | F1-score_std | AUC | AUC_std | MCC | MCC_std | Download model |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
FP2 fingerprints | 0.900 | 0.000 | 0.904 | 0.005 | 0.902 | 0.004 | 0.901 | 0.003 | 0.957 | 0.005 | 0.803 | 0.005 | Download |
Estate fingerprints | 0.761 | 0.009 | 0.811 | 0.007 | 0.786 | 0.005 | 0.781 | 0.003 | 0.884 | 0.005 | 0.575 | 0.008 | Download |
MACCS fingerprints | 0.888 | 0.004 | 0.828 | 0.004 | 0.858 | 0.004 | 0.860 | 0.000 | 0.930 | 0.000 | 0.716 | 0.007 | Download |
Daylight fingerprints | 0.816 | 0.005 | 0.802 | 0.000 | 0.809 | 0.003 | 0.810 | 0.000 | 0.860 | 0.000 | 0.617 | 0.007 | Download |
ECFP2 fingerprints | 0.922 | 0.004 | 0.906 | 0.007 | 0.914 | 0.005 | 0.914 | 0.005 | 0.980 | 0.000 | 0.828 | 0.006 | Download |
ECFP4 fingerprints | 0.923 | 0.007 | 0.949 | 0.000 | 0.936 | 0.005 | 0.936 | 0.005 | 0.990 | 0.000 | 0.876 | 0.005 | Download |
ECFP6 fingerprints | 0.898 | 0.004 | 0.976 | 0.005 | 0.937 | 0.005 | 0.934 | 0.005 | 0.990 | 0.000 | 0.874 | 0.005 | Download |
Positive dataset | Negative dataset |
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E-mail: biomed@csu.edu.cn