Target name

P20288: D(2) dopamine receptor


  Protein function

Dopamine receptor whose activity is mediated by G proteins which inhibit adenylyl cyclase.

  Database links

Uniprot primary ID P20288
PDB ID
DrugBank ID
BioGrid ID
GuidetoPHARMACOLOGY ID
PharmGKB ID
KEGG ID bta:281126
DIP ID
STRING ID 9913.ENSBTAP00000014422
IntAct ID
DMDM
BRENDA
Reactome
SignaLink
BioCyc
Entrez Gene (Gene ID) 281126
BindingDB P20288

  Model Performance Metrics

Fingerprint type Sensitivity SEN_std Specificity SPE_std Accuracy ACC_std F1-score F1-score_std AUC AUC_std MCC MCC_std Download model
FP2 fingerprints 0.905 0.007 0.837 0.008 0.871 0.003 0.877 0.005 0.930 0.000 0.744 0.008 Download
Estate fingerprints 0.821 0.014 0.803 0.009 0.812 0.009 0.814 0.012 0.900 0.000 0.626 0.019 Download
MACCS fingerprints 0.919 0.006 0.795 0.005 0.857 0.005 0.865 0.005 0.927 0.005 0.718 0.006 Download
Daylight fingerprints 0.790 0.005 0.816 0.007 0.803 0.005 0.802 0.004 0.855 0.005 0.609 0.007 Download
ECFP2 fingerprints 0.973 0.005 0.863 0.008 0.918 0.004 0.924 0.005 0.980 0.000 0.842 0.008 Download
ECFP4 fingerprints 0.983 0.005 0.931 0.005 0.957 0.005 0.960 0.000 0.990 0.000 0.915 0.005 Download
ECFP6 fingerprints 0.981 0.003 0.961 0.005 0.971 0.003 0.971 0.003 0.995 0.005 0.943 0.005 Download

  Download datasets

Positive dataset Negative dataset


Copyright @ 2012-2014 Computational Biology & Drug Design Group,
School of Pharmaceutical Sciences, Central South University. All rights reserved.

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 E-mail: biomed@csu.edu.cn